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Статті в журналах з теми "YAP/TEAD COMPLEX"
Pobbati, Ajaybabu V., and Brian P. Rubin. "Protein-Protein Interaction Disruptors of the YAP/TAZ-TEAD Transcriptional Complex." Molecules 25, no. 24 (December 18, 2020): 6001. http://dx.doi.org/10.3390/molecules25246001.
Повний текст джерелаKim, Jisook, Seung Hyun Jung, Seon Yeong Han, Jihee Yoon, Minjeong Kim, Jooyun Byun, Heesun Moon, et al. "Abstract 1614: Antitumor activity of novel and potent YAP/TAZ-TEAD inhibitorstargeting the Hippo pathway in solid tumors." Cancer Research 83, no. 7_Supplement (April 4, 2023): 1614. http://dx.doi.org/10.1158/1538-7445.am2023-1614.
Повний текст джерелаMoure, Casey J., Christopher Sondey, Mangeng Cheng, My Mansueto, Rafael Fernandez, Sebastian E. Schneider, Julia V. Ramirez, et al. "Abstract 3938: Discovery of a novel small molecule inhibitor of the YAP1/TAZ-TEAD transcriptional complex." Cancer Research 82, no. 12_Supplement (June 15, 2022): 3938. http://dx.doi.org/10.1158/1538-7445.am2022-3938.
Повний текст джерелаLi, Z., B. Zhao, P. Wang, F. Chen, Z. Dong, H. Yang, K. L. Guan, and Y. Xu. "Structural insights into the YAP and TEAD complex." Genes & Development 24, no. 3 (February 1, 2010): 235–40. http://dx.doi.org/10.1101/gad.1865810.
Повний текст джерелаLauriola, Angela, Elisa Uliassi, Matteo Santucci, Maria Laura Bolognesi, Marco Mor, Laura Scalvini, Gian Marco Elisi, et al. "Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library." Pharmaceutics 14, no. 2 (February 10, 2022): 391. http://dx.doi.org/10.3390/pharmaceutics14020391.
Повний текст джерелаSheldon, Caroline, Aaron Farley, Qing Ma, William T. Pu, and Zhiqiang Lin. "Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development." Cells 11, no. 18 (September 10, 2022): 2832. http://dx.doi.org/10.3390/cells11182832.
Повний текст джерелаKim, Eui Hyun, and Seok-Gu Kang. "CSIG-25. DIFFERENTIAL YAP ACTIVITY IN HUMAN GLIOBLASTOMA TUMORSPHERES AS A POTENTIAL BIOMARKER." Neuro-Oncology 24, Supplement_7 (November 1, 2022): vii44. http://dx.doi.org/10.1093/neuonc/noac209.174.
Повний текст джерелаKim, Cho-Long, Yu-Su Shin, Sue-Hee Choi, Seroc Oh, Kyeongseob Kim, Han-Sol Jeong, and Jung-Soon Mo. "Extracts of Perilla frutescens var. Acuta (Odash.) Kudo Leaves Have Antitumor Effects on Breast Cancer Cells by Suppressing YAP Activity." Evidence-Based Complementary and Alternative Medicine 2021 (February 15, 2021): 1–13. http://dx.doi.org/10.1155/2021/5619761.
Повний текст джерелаde Andrade, Leonardo Guedes, Valério Marques Portela, Esdras Corrêa Dos Santos, Karine de Vargas Aires, Rogério Ferreira, Daniele Missio, Zigomar da Silva, et al. "FSH Regulates YAP-TEAD Transcriptional Activity in Bovine Granulosa Cells to Allow the Future Dominant Follicle to Exert Its Augmented Estrogenic Capacity." International Journal of Molecular Sciences 23, no. 22 (November 16, 2022): 14160. http://dx.doi.org/10.3390/ijms232214160.
Повний текст джерелаCheng, Wen-Chih, Osnat Bohana-Kashtan, Sebastien Morisot, Nailing Zhang, Qian Chen, Duojia Pan, and Curt I. Civin. "The YAP Transcriptional Co-Activator Is Not Required for Mouse Hematopoiesis, at Steady State or After 5FU Treatment." Blood 116, no. 21 (November 19, 2010): 1592. http://dx.doi.org/10.1182/blood.v116.21.1592.1592.
Повний текст джерелаДисертації з теми "YAP/TEAD COMPLEX"
Gibault, Floriane. "Conception, synthèse et évaluation d’inhibiteurs du complexe protéique YAP-TEAD à visée anticancéreuse." Thesis, Lille 1, 2017. http://www.theses.fr/2017LIL10097.
Повний текст джерелаThe Hippo pathway, firstly described in Drosophila and highly conserved in mammals, has been demonstrated to play a crucial role in the organ size control. This kinase cascade regulates the phosphorylation of the downstream effector YAP (or its paralogue TAZ), a transcriptional coactivator with oncogenic activity. Its function is mediated by its nuclear translocation and interaction with the transcriptional factor TEAD, to form YAP-TEAD complex which activates the genes expression in charge of cell proliferation triggering organ growth. Overexpression of YAP/TAZ/TEAD protein in several cancers disrupts the Hippo pathway balance and urges on YAP-TEAD complex formation causing excessive proliferation and cancer development. Inhibiting this protein-protein interaction is thus a promising therapeutic target for the design of new anti-cancer drugs. In this goal, the laboratory has considered two strategies. The first one consists in targeting the YAP protein by synthesizing dipyrrins, representing Verteporfin fragments to define the minimal requirement yielding the expected biological activity. A second approach involves synthesizing TEAD ligands able to fit in specific interface 3. Based on molecular modeling, a triazole scaffold family was optimized to establish structure-activity relationship. Thanks to the biological and binding tests development, synthesized molecules evaluation is still in progress and the present first results have already allowed identifying a promising compound
SINGH, SIMRAN. "EXPLORING NATURAL COMPOUNDS TARGETING THE HIPPO PATHWAY FOR POTENTIAL TREATMENT OF MENINGIOMA." Thesis, 2023. http://dspace.dtu.ac.in:8080/jspui/handle/repository/19944.
Повний текст джерелаКниги з теми "YAP/TEAD COMPLEX"
Cappuccio, Massimiliano L., ed. Handbook of Embodied Cognition and Sport Psychology. The MIT Press, 2019. http://dx.doi.org/10.7551/mitpress/10764.001.0001.
Повний текст джерелаЧастини книг з теми "YAP/TEAD COMPLEX"
Hsu, Wynne, Mong Li Lee, and Junmei Wang. "Mining Spatio-Temporal Graph Patterns." In Temporal and Spatio-Temporal Data Mining, 227–61. IGI Global, 2008. http://dx.doi.org/10.4018/978-1-59904-387-6.ch011.
Повний текст джерелаТези доповідей конференцій з теми "YAP/TEAD COMPLEX"
Velazquez, Antonio, and R. Andrew Swartz. "Gyroscopic Effects of Horizontal Axis Wind Turbines Using Stochastic Aeroelasticity via Spinning Finite Elements." In ASME 2012 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/smasis2012-8118.
Повний текст джерелаDurali, Mohammad, and Mohammad Mahdi Jalili. "Time Saving Simulation of Long Train Derailment." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-66885.
Повний текст джерелаAlexandre, Armando, Raffaello Antonutti, Theo Gentils, Laurent Mutricy, and Pierre Weyne. "Simplified Aerodynamic Loading Model for Non-Production Conditions for Floating Wind Systems Design." In ASME 2021 3rd International Offshore Wind Technical Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/iowtc2021-3516.
Повний текст джерелаRuiz Toledo, Maria Mercedes. "Propuesta de material didáctico desde el diseño visual acotado en la inclusión y el entorno educativo infantil autista del centro Neurokids." In Encuentro de investigación formativa en Diseño – Semilleros y Grupos de investigación RAD 2019. Pasto, Colombia: Red Académica de Diseño - RAD, 2019. http://dx.doi.org/10.53972/rad.eifd.2019.2.5.
Повний текст джерела