Статті в журналах: "Weak reactivity"

1

Johnson, Elizabeth J., Claudia Kleinlein, Rebecca A. Musgrave, and Theodore A. Betley. "Diiron oxo reactivity in a weak-field environment." Chemical Science 10, no. 25 (2019): 6304–10. http://dx.doi.org/10.1039/c9sc00605b.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

A dinucleating cofacial Pacman dipyrrin ligand platform was utilized to isolate diiron bridging oxo complexes in a variety of oxidation states. The interplay between oxidation state and acid/base reactivity in diiron μ-oxo units is explored herein.

2

Neumann, Eberhard. "Digression on biochemical membrane reactivity in weak electromagnetic fields." Bioelectrochemistry and Bioenergetics 16, no. 3 (December 1986): 565–67. http://dx.doi.org/10.1016/0302-4598(86)80078-2.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

3

Morelati, F., N. Revelli, F. Drago, P. Mancuso, and G. Sirchia. "Reactivity of 62 Rh MAbs with weak and variant antigens." Transfusion Clinique et Biologique 3, no. 6 (January 1996): 359–66. http://dx.doi.org/10.1016/s1246-7820(96)80044-9.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

4

Botti, C., E. Seregni, S. Ménard, P. Collini, E. Tagliabue, M. Campiglio, B. Vergani, et al. "Two Novel Monoclonal Antibodies against the MUC4 Tandem Repeat Reacting with an Antigen Overexpressed by Lung Cancer." International Journal of Biological Markers 15, no. 4 (October 2000): 312–20. http://dx.doi.org/10.1177/172460080001500406.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

In this study we investigated the immunochemical and cytochemical reactivity of two monoclonal antibodies against the 16-amino acid tandem repeat of MUC4 to demonstrate a possible variation of the mucin core peptide expression related to lung cancer. The immunocytochemical anti-MUC4 reactivity was analyzed in four lung cancer cell lines (Calu-1, Calu-3, H460, SKMES) and in other tumor cell lines, as well as in frozen materials from 21 lung adenocarcinomas (ACs), including five bronchioloalveolar carcinomas (BACs), and 11 squamous cell lung carcinomas (SqCCs). A weak fluorescence anti-MUC4 positivity (range: 10.3–16.2) was observed only in acetone-fixed lung cancer cell lines Calu-1, Calu-3 and H460. These three lung cancer cell lines also showed a cytoplasmic immunoperoxidase reactivity. The immunostaining in lung cancer tissues showed a granular cytoplasmic reactivity: 15/21 (71%) and 17/21 (80%) ACs were positive with BC-LuC18.2 and BC-LuCF12, respectively. All BACs were positive. Moderate to strong reactivity was present in well-differentiated ACs. In the normal lung parenchyma counterparts weak reactivity was found only in bronchiolar cells. All SqCCs were negative. Anti-MUC4 reactivity was also observed in the alveolar mucus. In conclusion, our anti-MUC4 MAbs detect a secretion product present in mucus and this product is elaborated by lung cancer cells and overexpressed in well-differentiated lung ACs.

5

Shiozawa, M., K. Yasuda, S. Yamashita, and S. Aiso. "Distribution of gamma-glutamyl transpeptidase in human salivary glands: immunohistochemical study using a monoclonal antibody." Journal of Histochemistry & Cytochemistry 41, no. 2 (February 1993): 205–13. http://dx.doi.org/10.1177/41.2.8093456.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

We studied in detail the distribution pattern of gamma-glutamyl transpeptidase (gamma-GT) in human salivary glands using a monoclonal antibody (MAb) to human kidney gamma-GT. In the sublingual gland, a strong reactivity of the enzyme was recognized along the luminal and lateral membranes of serous cells. Weak but positive reactivity was noted on the luminal membrane of mucous cells. The intercellular canaliculi in the demilune and luminal surfaces of excretory duct cells were also immunoreactive. In the submandibular gland, a weak reaction was observed on the luminal membrane of intercalated duct cells and striated duct cells. Faint reactivity was seen on the luminal membrane of striated duct cells of the parotid gland. No reaction was observed in serous cells of the parotid gland. The immunoreaction in the sublingual gland was stronger than that in submandibular or parotid glands.

6

Wozniak, Derek I., Andrew J. Hicks, William A. Sabbers, and Graham E. Dobereiner. "Imidazolyl-phenyl (IMP) anions: a modular structure for tuning solubility and coordinating ability." Dalton Transactions 48, no. 37 (2019): 14138–55. http://dx.doi.org/10.1039/c9dt03511g.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

7

Sacramento, Jireh Joy D., and David P. Goldberg. "The hydrogen atom transfer reactivity of a porphyrinoid cobalt superoxide complex." Chemical Communications 55, no. 7 (2019): 913–16. http://dx.doi.org/10.1039/c8cc08453j.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

8

Hossain, M. Azad, Myung-Jong Jin, and William A. Donaldson. "Reactivity of acyclic (pentadienyl)iron(1+) cations with weak carbon nucleophiles." Journal of Organometallic Chemistry 630, no. 1 (July 2001): 5–10. http://dx.doi.org/10.1016/s0022-328x(01)00869-5.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

9

Bhagavathi, M. S., N. Das, S. Prakash, A. Sahu, S. Routray, and S. Mukherjee. "Blood group discrepancy in A_h para-Bombay phenotype: a rare blood group variant and its clinical significance." Immunohematology 37, no. 4 (January 1, 2021): 160–64. http://dx.doi.org/10.21307/immunohematology-2021-026.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Abstract Individuals with the rare para-Bombay phenotype have inherited defects in producing H associated with FUT1 and/or FUT2 genes. We report a case of blood group discrepancy in a para-Bombay patient from a tertiary care hospital of eastern India. A 31-year-old woman with rheumatic heart disease presented with fatigue and breathlessness and was then scheduled for valvuloplasty, for which a blood transfusion request was sent to the blood center. During pre-transfusion testing, red blood cell (RBC) testing showed group O, and serum testing showed strong reactivity with group B RBCs, weak reactivity with group O RBCs, and very weak reactivity with group A RBCs. Saliva inhibition testing and enzyme treatment of RBCs concluded the patient to be of “Ah para-Bombay” phenotype. The patient’s Lewis phenotype was Le(a–b+). This patient’s serum also had cold-reacting anti-IH along with anti-B. This case report highlights the importance of performing an advanced immunohematologic workup, including adsorption, elution, enzyme treatment, and saliva inhibition testing for identification of weak A or B subgroups as well as the rare para-Bombay blood group, when routine ABO typing, using forward and reverse grouping, is inconclusive. Accurate identification of blood group helps in preventing transfusion-related adverse events and encouraging safe transfusion practice.

10

Gongora-Rivera, Fernando, Adolfo Cordero-Perez, Alejandro Gonzalez-Aquines, Antonio Anaya-Escamilla, Eduardo Villarreal-Garza, Meztli Espinosa-Ortega, Mario C. Salinas-Carmona, and Xochilt Ortiz-Jimenez. "Impaired Cerebral Vasomotor Reactivity in Alzheimer’s Disease." International Journal of Alzheimer's Disease 2018 (September 9, 2018): 1–5. http://dx.doi.org/10.1155/2018/9328293.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Background. Recent studies have shown that cerebral vascularity may be impaired in Alzheimer’s disease. Cerebral vasomotor reactivity could be an important biomarker for this pathology.Aims. The aim of this study was to investigate the alterations in cerebral vascular motor reactivity in Alzheimer’s disease subjects and to associate these changes with their cognitive scores.Methods. We recruited subjects with a diagnosis of Alzheimer’s disease and healthy controls. Demographic, clinical, imaging, and cognitive test were obtained. Then all participants performed a cerebral vascular motor reactivity test with 7% CO2 and cerebral blood flow velocities (CBFV) were recorded with transcranial doppler ultrasound before and after the test.Results. We recruited 45 subjects, 26 (21 female) Alzheimer’s disease participants and 19 (15 female) healthy controls. There were no differences in baseline cerebral blood flow velocities between the groups. After the cerebral vasomotor reactivity test, absolute mean difference in mean CBFV (ΔCBFV-m) was 8.70±4.14 versus 4.81±6.96 (p<0.01), respectively. Calculated percentage of change (%CVMR) was lower in the AD group 7.45±18.25 versus 23.29±17.48, and there was a positive but weak correlation with mini-mental scores (ρ=0.337, p=0.023).Conclusions. In this study, Alzheimer’s disease subjects showed significant changes in all absolute cerebral blood flow velocities after the cerebral vasomotor reactivity test with CO2, but only diastolic phase responses were statistically significant. There was a positive but weak correlation between cerebral vasomotor reactivity and cognitive scores. Further studies are needed to investigate these effects in larger Latin-American samples.

11

Nishikawa, Sumio. "Presence of Anti-cystatin C–positive Dendritic Cells or Macrophages and Localization of Cysteine Proteases in the Apical Bud of the Enamel Organ in the Rat Incisor." Journal of Histochemistry & Cytochemistry 53, no. 5 (May 2005): 643–51. http://dx.doi.org/10.1369/jhc.4a6533.2005.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Cystatin C, a cysteine protease inhibitor, was examined in the apical buds of rat incisors by immunohistochemistry, because in transition and maturation zones most of the dendritic cells in the papillary layer are anti-cystatin C–positive. Anti-cystatin C–labeled cells were sparse and localized to the proliferation and differentiation zones, constituting the apical bud of 5-week-old rat incisors. These cells were considered macrophages or dendritic cells, based on their reactivity with OX6 and ED1, as well as their ultrastructure. Basement membrane at the periphery of apical bud was also labeled by anti-cystatin C antibody. The apical buds included a few apoptotic fragments and weak reactivity with antibody to cathepsin L, a cysteine protease. Reactivity to anti-cystatin C and anti-cathepsin ∗∗∗L antibodies was also detected in the apical bud of newborn rat incisors. These results suggest that the cystatin C–positive macrophages or dendritic cells are involved in normal incisor formation. They may be related to the clearance of apoptotic cells or protection from putative cysteine protease activity.

12

Schreiber, A. M., and J. L. Specker. "Metamorphosis in the summer flounder Paralichthys dentatus: changes in gill mitochondria-rich cells." Journal of Experimental Biology 202, no. 18 (September 15, 1999): 2475–84. http://dx.doi.org/10.1242/jeb.202.18.2475.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Salinity tolerance changes during larval development and metamorphosis in the summer flounder (Paralichthys dentatus) and other teleosts. The physiological mechanisms responsible for osmoregulation during these early stages of development are not well understood. This study characterized changes in ultrastructure, intracellular membranes and immunoreactive Na(+)/K(+)-ATPase of mitochondria-rich cells (MRCs) in the gills of summer flounder during metamorphosis. Gill ultrastructure at the start of metamorphosis revealed only one type of MRC, which had weak reactivity to osmium and lacked a well-defined apical pit. In juveniles, two types of MRCs were observed: light-staining MRCs (LMRCs) with weak reactivity to osmium, and dark-staining MRCs (DMRCs) with strong reactivity to osmium and positioned adjacent to LMRCs. Compared with MRCs at the start of metamorphosis, the mitochondria of juvenile MRCs appeared smaller, with more transverse cristae and electron-dense matrices. Changes in MRCs during metamorphosis were also accompanied by increased immunoreactive Na(+)/K(+)-ATPase. These findings suggest that gill MRCs develop during the metamorphosis of summer flounder as the gill takes on an increasingly important osmoregulatory role.

13

Pandey, Sarvesh Kumar, Mohammad Faheem Khan, Shikha Awasthi, Reetu Sangwan, and Sudha Jain. "A Quantum Theory of Atoms-in-Molecules Perspective and DFT Study of Two Natural Products: Trans-Communic Acid and Imbricatolic Acid." Australian Journal of Chemistry 70, no. 3 (2017): 328. http://dx.doi.org/10.1071/ch16406.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

The topological features of the charge densities, ρ(r), and the chemical reactivity of two most biologically relevant and chemically interesting scaffold systems i.e. trans-communic acid and imbricatolic acid have been determined using density functional theory. To identify, characterize, and quantify efficiently, the non-covalent interactions of the atoms in the molecules have been investigated quantitatively using Bader's quantum theory of atoms-in-molecules (QTAIM) technique. The bond path is shown to persist for a range of weak H···H as well as C···H internuclear distances (in the range of 2.0–3.0 Å). These interactions exhibit all the hallmarks of a closed-shell weak interaction. To get insights into both systems, chemical reactivity descriptors, such as HOMO–LUMO, ionization potential, and chemical hardness, have been calculated and used to probe the relative stability and chemical reactivity. Some other useful information is also obtained with the help of several other electronic parameters, which are closely related to the chemical reactivity and reaction paths of the products investigated. Trans-communic acid seems to be chemically more sensitive when compared with imbricatolic acid due to its experimentally observed higher half-maximal inhibitory concentration (bioactivity parameter) value, which is in accordance with its higher chemical reactivity as theoretically predicted using density functional theory-based reactivity index. The quantum chemical calculations have also been performed in solution using different solvents, and the relative order of their structural and electronic properties as well as QTAIM-based parameters show patterns similar to those observed in gas phase only. This study further exemplifies the use and successful application of the bond path concept and the quantum theory of atoms-in-molecules.

14

Kuwabara, Junpei, Maxim V. Ovchinnikov, Charlotte L. Stern, and Chad A. Mirkin. "Reactivity of Dinuclear Rhodium(I) Macrocycles Formed via the Weak-Link Approach." Organometallics 27, no. 4 (February 2008): 789–92. http://dx.doi.org/10.1021/om700926d.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

15

Cooksley, Helen, Shilpa Chokshi, Yafit Maayan, Heiner Wedemeyer, Pietro Andreone, Richard Gilson, Thomas Warnes, et al. "Hepatitis B Virus e Antigen Loss during Adefovir Dipivoxil Therapy Is Associated with Enhanced Virus-Specific CD4+ T-Cell Reactivity." Antimicrobial Agents and Chemotherapy 52, no. 1 (November 5, 2007): 312–20. http://dx.doi.org/10.1128/aac.00467-07.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

ABSTRACT Weak T-cell reactivity to hepatitis B virus (HBV) is thought to be the dominant cause for chronic HBV infection. Treatment with adefovir dipivoxil (ADV) increases the rate of HBV e antigen (HBeAg) loss; however, the immune mechanisms associated with this treatment response are not understood. Serial analysis of HBV-specific CD4+ T-cell reactivity was performed during 48 weeks of therapy with ADV and correlated with treatment outcome for 19 HBeAg-positive patients receiving ADV (n = 13) or the placebo (n = 6). We tested T-cell reactivity to HBV at seven protocol time points by proliferation, cytokine production, and enzyme-linked immunospot assays. A panel of serum cytokines was quantitated by cytokine bead array. ADV-treated patients showed increased CD4+ T-cell responses to HBV and lower serum levels of cytokines compared to those of placebo-treated patients. Enhanced CD4+ T-cell reactivity to HBV, which peaked at treatment week 16, was confined to a subgroup of ADV-treated patients who achieved greater viral suppression (5.3 ± 0.3 log10 copies/ml [mean ± standard error of the mean {SEM}] serum HBV DNA reduction from baseline) and HBeAg loss, but not to ADV-treated patients with moderate (3.4 ± 0.2 log10 copies/ml [mean ± SEM]) viremia reduction who remained HBeAg positive or to patients receiving the placebo. In conclusion, T-cell reactivity to HBV increases in a proportion of ADV-treated patients and is associated with greater suppression of HBV replication and HBeAg loss.

16

Ibni Hashim, Ishfaq, Thomas Scattolin, Nikolaos V. Tzouras, Laurens Bourda, Kristof Van Hecke, Ida Ritacco, Lucia Caporaso, Luigi Cavallo, Steven P. Nolan, and Catherine S. J. Cazin. "Straightforward synthesis of [Cu(NHC)(alkynyl)] and [Cu(NHC)(thiolato)] complexes (NHC = N-heterocyclic carbene)." Dalton Transactions 51, no. 1 (2022): 231–40. http://dx.doi.org/10.1039/d1dt03710b.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Synthetic access to monomeric copper-alkynyl and copper-thiolato complexes of the type [(NHC)Cu(R)] (R = alkynyl or thiolato) using a weak base approach is reported. Computational studies and reactivity tests are also presented.

17

Kroll, Alexander, Henning Steinert, Lennart T. Scharf, Thorsten Scherpf, Bert Mallick, and Viktoria H. Gessner. "A diamino-substituted carbodiphosphorane as strong C-donor and weak N-donor: isolation of monomeric trigonal-planar L·ZnCl2." Chemical Communications 56, no. 58 (2020): 8051–54. http://dx.doi.org/10.1039/d0cc02496a.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Studies of the reactivity and coordination properties of the diamino-carbodiphosphorane 1 revealed that 1 is a weak N donor, but strongly coordinates via the carbon atom thus allowing the isolation of low-valent metal species.

18

Mittra, Kaustuv, Asmita Singha, and Abhishek Dey. "Iron porphyrins with a hydrogen bonding cavity: effect of weak interactions on their electronic structure and reactivity." Dalton Transactions 45, no. 47 (2016): 18796–802. http://dx.doi.org/10.1039/c6dt03597c.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

19

Sun, Xiuyun, Xia Yao, Chao Zhang, and Yu Rao. "Pd(ii) catalyzed ortho C–H iodination of phenylcarbamates at room temperature using cyclic hypervalent iodine reagents." Chemical Communications 51, no. 49 (2015): 10014–17. http://dx.doi.org/10.1039/c5cc02533h.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

The first example to access ortho iodinated phenols using cyclic hypervalent iodine(iii) reagents through palladium(ii) catalyzed C–H activation has been developed via weak coordination. The reaction showed excellent regioselectivity, reactivity and good functional group tolerance. A unique mechanism was proposed.

20

Haustein, U. F., B. Pustowoit, U. Krusche, and K. Herrmann. "Antibodies to retrovirus proteins in scleroderma." Acta Dermato-Venereologica 73, no. 2 (April 1, 1993): 116–18. http://dx.doi.org/10.2340/0001555573116118.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

In 8 out of 29 patients with scleroderma we found antibodies to HIV retroviral proteins in the Western blot analysis. The sera reacted only to one or two of the following bands: p 18, p 24, p 55, p 65 in relatively weak grades. There were no evident clinical correlations with the reactivity of certain bands, nor signs of direct HIV infection in our patients. Apart from 3 cases with positive CMV reactivity (IgM), there was no cross/reactivity to HTLV I or EBV (IgM) and to topoisomerase (Scl 70) or other autoantibodies to various nuclear antigens related to scleroderma. It is not clear whether retroviruses are involved in the pathogenesis of scleroderma or whether these antibodies are due to molecular mimicry.

21

Lin, Tao, Xin Zhang, Rong Li, Gui Quan Zhang, and Ting Bai. "Sol-Gel Synthesized Fe-P-O Catalyst for the Benzylation of Benzene with Benzyl Chloride." Advanced Materials Research 284-286 (July 2011): 2141–45. http://dx.doi.org/10.4028/www.scientific.net/amr.284-286.2141.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Three Fe-P-O catalysts were prepared by different methods. The as-prepared catalysts were comparatively characterized by N2 isothermal adsorption-desorption, XRD, SEM and Py-IR techniques. The reactivity of these catalysts was tested in the benzylation of benzene with benzyl chloride. So-gel prepared Fe-P-O catalyst showed the highest activity among these catalysts and could keep high reactivity even after six reactions cycled because it is not only the large-surface-area superfine particle but also has a large amount of weak and medium Lewis acid sites.

22

Hossain, M. Azad, Myung-Jong Jin, and William A. Donaldson. "ChemInform Abstract: Reactivity of Acyclic (Pentadienyl)iron(1+) Cations with Weak Carbon Nucleophiles." ChemInform 33, no. 3 (May 23, 2010): no. http://dx.doi.org/10.1002/chin.200203184.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

23

Syed, Sajjad, Anne-Marie Martin, Helen Haupt, Victoria Podolski, and John J. Brooks. "Frequent Detection of Androgen Receptors in Spindle Cell Lipomas: An Explanation for This Lesion's Male Predominance?" Archives of Pathology & Laboratory Medicine 132, no. 1 (January 1, 2008): 81–83. http://dx.doi.org/10.5858/2008-132-81-fdoari.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Abstract Context.—Spindle cell lipoma (SCL) is a tumor with marked male predilection. We discovered one SCL that exhibited strong immunoreactivity for androgen receptors (ARs) in the spindle cells. Objective.—The hypothesis was that ARs in SCLs would not be rare and that all or nearly all SCLs would be AR positive, perhaps explaining its male predominance. Design.—Twenty-eight cases of SCL (22 men, 6 women) and a control group of 20 conventional lipomas (10 men, 10 women) were stained with monoclonal AR antibody (1: 150; Dako, Carpinteria, Calif) using the Ventana Discovery. Only nuclear reactivity was considered positive, as noted in prostate controls. Cell types (fat, spindle cells) and extent of staining were recorded as rare, considered negative, focal (1+), or diffuse (2+/3+). Results.—All 22 cases of SCL in men were positive for ARs. Twenty showed diffuse (2+/3+) reactivity mainly in the spindle cells. Of the 6 SCLs in women, 1 was AR negative, 1 showed a 3+ reaction in the spindle cells, and 4 had weak (1+) staining of spindle cells. Overall, 96% of SCLs were AR positive, including 83% of SCLs in women. Seventy percent of conventional lipomas showed positive staining in fat, but only 2 showed 2+ staining. In the rest, staining was rare or weak (1+). Conclusions.—Nearly all SCLs exhibited AR reactivity. However, the presence of ARs in a substantial percentage of ordinary lipomas and in SCLs in females mitigates against the hypothesis that AR reactivity alone can explain the marked male predominance of SCL.

24

Shader, Tiffany M., Lisa M. Gatzke-Kopp, Sheila E. Crowell, M. Jamila Reid, Julian F. Thayer, Michael W. Vasey, Carolyn Webster-Stratton, Ziv Bell, and Theodore P. Beauchaine. "Quantifying respiratory sinus arrhythmia: Effects of misspecifying breathing frequencies across development." Development and Psychopathology 30, no. 1 (May 30, 2017): 351–66. http://dx.doi.org/10.1017/s0954579417000669.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

AbstractLow resting respiratory sinus arrhythmia (RSA), and to a lesser extent excessive RSA reactivity to emotion evocation, are observed in many psychiatric disorders characterized by emotion dysregulation, including syndromes spanning the internalizing and externalizing spectra, and other conditions such as nonsuicidal self-injury. Nevertheless, some inconsistencies exist. For example, null outcomes in studies of RSA–emotion dysregulation relations are sometimes observed among younger participants. Such findings may derive from use of age inappropriate frequency bands in calculating RSA. We combine data from five published samples (N = 559) spanning ages 4 to 17 years, and reanalyze RSA data using age-appropriate respiratory frequencies. Misspecifying respiratory frequencies results in overestimates of resting RSA and underestimates of RSA reactivity, particularly among young children. Underestimates of developmental shifts in RSA and RSA reactivity from preschool to adolescence were also observed. Although correlational analyses revealed weak negative associations between resting RSA and aggression, those with clinical levels of externalizing exhibited lower resting RSA than their peers. No associations between RSA reactivity and externalizing were observed. Results confirm that age-corrected frequency bands should be used when estimating RSA, and that literature-wide overestimates of resting RSA, underestimates of RSA reactivity, and underestimates of developmental shifts in RSA and RSA reactivity may exist.

25

Marcus, Assaf, Dinorah Friedmann-Morvinski, Eran Elinav, Tova Waks, and Zelig Eshhar. "Hierarchy of T cell lineage decision is regulated by thymic self-reactive signaling (36.45)." Journal of Immunology 184, no. 1_Supplement (April 1, 2010): 36.45. http://dx.doi.org/10.4049/jimmunol.184.supp.36.45.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Abstract During T cell development, thymic recognition of self antigens leads to negative selection of effector T cells with high TCR avidity. Similar interactions are implicated with emergence of regulatory subsets, including Tregs, NKT, and CD8αα cells. How the degree of self-reactive signaling coordinates the development of the effector and regulatory subpopulations is not fully understood. To elucidate this, we employed transgenic mice, featuring gradually increasing self-reactivity by expression of different levels of a cross-reactive tripartite chimeric receptor targeting 2,4,6-trinitrophenol (TNP). In these mice, increasing cell self-reactivity inversely correlated with effector cell numbers, and led to skewing towards CD4 phenotype, compatible with the kinetic signaling model. In parallel, coreceptor levels of expression were diminished in correlation with gradually increasing self-reactivity, reflecting coreceptor tuning. Higher levels of self-reactive signaling promoted the thymic expansion of CD8αα and NKT cells. T cells with the highest self-reactive TPCR featured defective TCR rearrangement stemming from down regulation of RAG1, RAG2 and PTα. Altogether, we demonstrate a hierarchical order in coping of the immune system with auto-reactivity. In case of weak self-reactivity, coreceptor tuning is implemented, while in stronger self-reactivity, regulatory subsets develop, as possible means of modulating dangerous autoreactive cells into protective guardians of host.

26

Smits, Fenne M., Dennis J. L. G. Schutter, Jack van Honk, and Elbert Geuze. "Does non-invasive brain stimulation modulate emotional stress reactivity?" Social Cognitive and Affective Neuroscience 15, no. 1 (January 2020): 23–51. http://dx.doi.org/10.1093/scan/nsaa011.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Abstract Excessive emotional responses to stressful events can detrimentally affect psychological functioning and mental health. Recent studies have provided evidence that non-invasive brain stimulation (NBS) targeting the prefrontal cortex (PFC) can affect the regulation of stress-related emotional responses. However, the reliability and effect sizes have not been systematically analyzed. In the present study, we reviewed and meta-analyzed the effects of repetitive transcranial magnetic (rTMS) and transcranial direct current stimulation (tDCS) over the PFC on acute emotional stress reactivity in healthy individuals. Forty sham-controlled single-session rTMS and tDCS studies were included. Separate random effects models were performed to estimate the mean effect sizes of emotional reactivity. Twelve rTMS studies together showed no evidence that rTMS over the PFC influenced emotional reactivity. Twenty-six anodal tDCS studies yielded a weak beneficial effect on stress-related emotional reactivity (Hedges’ g = −0.16, CI95% = [−0.33, 0.00]). These findings suggest that a single session of NBS is insufficient to induce reliable, clinically significant effects but also provide preliminary evidence that specific NBS methods can affect emotional reactivity. This may motivate further research into augmenting the efficacy of NBS protocols on stress-related processes.

27

Serrada-Tejeda, Sergio, Patricia Sánchez-Herrera-Baeza, Rosa M. Martínez-Piédrola, Nuria Máximo-Bocanegra, Nuria Trugeda-Pedrajo, M. ª. Pilar Rodríguez-Pérez, Gemma Fernández-Gómez, and Marta Pérez-de-Heredia-Torres. "Prospective One-Year Follow-Up of Sensory Processing in Phelan–McDermid Syndrome." Children 10, no. 6 (June 20, 2023): 1086. http://dx.doi.org/10.3390/children10061086.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Background: Phelan–McDermid syndrome (PMS) is caused by the loss (deletion) of a small portion of chromosome 22 in a region designated q13.3 (22q13.3 deletion). PMS is one of the most common genetic forms of autism spectrum disorder (ASD) in which sensory reactivity difficulties have been described on limited occasions. Methods: The objective of this study is to identify whether changes in sensory reactivity skills occur after one year of follow-up in a group of 44 participants diagnosed with PMS. All participants completed the Short Sensory Profile (SSP). Two-factor ANOVA tests were performed with repeated measures for the study of the evolution of the scores. Results: Participants with PMS showed significant changes after one year of follow-up in sensory reactivity skills associated with tactile hyperreactivity (p = 0.003). The rest of the study variables did not show significant differences compared to the baseline assessment, showing definite differences associated with patterns of hypo-responsiveness and sensory seeking, low/weak energy, and difficulties in auditory filtering. Conclusions: Understanding the evolution of sensory reactivity skills can facilitate the adjustment to behavioral changes in people with PMS and design-targeted interventions to address sensory reactivity challenges.

28

Xia, Chenjie, Alexandra Touroutoglou, Karen S. Quigley, Lisa Feldman Barrett, and Bradford C. Dickerson. "Salience Network Connectivity Modulates Skin Conductance Responses in Predicting Arousal Experience." Journal of Cognitive Neuroscience 29, no. 5 (May 2017): 827–36. http://dx.doi.org/10.1162/jocn_a_01087.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Individual differences in arousal experience have been linked to differences in resting-state salience network connectivity strength. In this study, we investigated how adding task-related skin conductance responses (SCR), a measure of sympathetic autonomic nervous system activity, can predict additional variance in arousal experience. Thirty-nine young adults rated their subjective experience of arousal to emotionally evocative images while SCRs were measured. They also underwent a separate resting-state fMRI scan. Greater SCR reactivity (an increased number of task-related SCRs) to emotional images and stronger intrinsic salience network connectivity independently predicted more intense experiences of arousal. Salience network connectivity further moderated the effect of SCR reactivity: In individuals with weak salience network connectivity, SCR reactivity more significantly predicted arousal experience, whereas in those with strong salience network connectivity, SCR reactivity played little role in predicting arousal experience. This interaction illustrates the degeneracy in neural mechanisms driving individual differences in arousal experience and highlights the intricate interplay between connectivity in central visceromotor neural circuitry and peripherally expressed autonomic responses in shaping arousal experience.

29

Zhang, Zhiyuan, Kenichi Niikura, Xue-Fei Huang, and Chi-Huey Wong. "A strategy for the one-pot synthesis of sialylated oligosaccharides." Canadian Journal of Chemistry 80, no. 8 (August 1, 2002): 1051–54. http://dx.doi.org/10.1139/v02-131.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

A new strategy has been developed for the synthesis of branched sialylated oligosaccharides using one-pot technology. Sialyl donors are in general too weak in reactivity to be used as the first glycosyl donors in the one-pot synthesis. When sialic acid is linked to a different sugar such as galactose, the reactivity is, however, significantly enhanced and can be tuned to enable the one-pot synthesis. A combination of NISTfOHAgOTf was used for activation of the thioglycosides to improve the glycosylation yield when a hindered acceptor was used, as illustrated in the one-pot assembly of sialylated hexasaccharide.Key words: one-pot synthesis, sialyl oligosaccharides, new activation.

30

SUZUKI, Takanori. "Weak Intermolecular Interaction in Crystal Affecting the Recognition Properties and the Solid-State Reactivity." Journal of Synthetic Organic Chemistry, Japan 53, no. 5 (1995): 403–12. http://dx.doi.org/10.5059/yukigoseikyokaishi.53.403.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

31

Haseba, Takeshi, Kazuhiro Matsushita, Toshihiro Asakura, Kouji Kameyama, Takeshi Tamaki, Shoichi Okouchi, Tokinori Watanabe, and Hisashi Uedaira. "Diminution of Biological Reactivity of Ethanol by Changing the Solution Structure by Weak Ultrasonication." Alcoholism: Clinical and Experimental Research 17, no. 5 (September 1993): 963–67. http://dx.doi.org/10.1111/j.1530-0277.1993.tb05649.x.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

32

Santos, V., K. Barthelet, I. Gener, C. Canaff, and P. Magnoux. "Development of a new model reaction to characterize the weak reactivity of cationic zeolites." Microporous and Mesoporous Materials 114, no. 1-3 (September 2008): 262–69. http://dx.doi.org/10.1016/j.micromeso.2008.01.012.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

33

Gao, Ang, Krishna Shrinivas, Paul Lepeudry, Hiroshi I. Suzuki, Phillip A. Sharp, and Arup K. Chakraborty. "Evolution of weak cooperative interactions for biological specificity." Proceedings of the National Academy of Sciences 115, no. 47 (November 7, 2018): E11053—E11060. http://dx.doi.org/10.1073/pnas.1815912115.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

A hallmark of biological systems is that particular functions and outcomes are realized in specific contexts, such as when particular signals are received. One mechanism for mediating specificity is described by Fisher’s “lock and key” metaphor, exemplified by enzymes that bind selectively to a particular substrate via specific finely tuned interactions. Another mechanism, more prevalent in multicellular organisms, relies on multivalent weak cooperative interactions. Its importance has recently been illustrated by the recognition that liquid-liquid phase transitions underlie the formation of membraneless condensates that perform specific cellular functions. Based on computer simulations of an evolutionary model, we report that the latter mechanism likely became evolutionarily prominent when a large number of tasks had to be performed specifically for organisms to function properly. We find that the emergence of weak cooperative interactions for mediating specificity results in organisms that can evolve to accomplish new tasks with fewer, and likely less lethal, mutations. We argue that this makes the system more capable of undergoing evolutionary changes robustly, and thus this mechanism has been repeatedly positively selected in increasingly complex organisms. Specificity mediated by weak cooperative interactions results in some useful cross-reactivity for related tasks, but at the same time increases susceptibility to misregulation that might lead to pathologies.

34

Gomila, Isabel, Maria Ángeles Leciñena, Miguel Ángel Elorza, Yolanda Pastor, Laura Sahuquillo, Miguel Servera, Jordi Puiguriguer, and Bernardino Barcelo. "Detectability of Dissociative Psychoactive Substances in Urine by Five Commercial Phencyclidine Immunoassays." Journal of Analytical Toxicology 43, no. 6 (April 23, 2019): 497–503. http://dx.doi.org/10.1093/jat/bkz026.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Abstract Methoxetamine (MXE) and the arylcyclohexylamines 3-methoxy-PCP (3-MeO-PCP) and 4-methoxy-PCP (4-MeO-PCP) are substituted analogs of the dissociative psychoactive substances ketamine and phencyclidine (PCP), respectively. They have emerged on the new psychoactive substances (NPS) market as legal alternatives to these classically banned dissociatives. Little data has been published regarding the cross-reactivity of these NPS in PCP immunoassays (IAs). The aim of this work was to explore the possibilities of detecting 3-MeO-PCP, 4-MeO-PCP, MXE and ketamine in commercial IAs for PCP. The cross-reactivity study was performed in five different PCP IAs using urine-free, spiked samples and urine samples obtained from two 3-MeO-PCP overdose cases. 3-MeO-PCP and 4-MeO-PCP showed cross-reactivity (ranging from 1–143%) in all PCP IAs evaluated. MXE only showed very weak cross-reactivity (ranged from 0.04 to 0.25%) and ketamine was not detected in any PCP IA evaluated. Urine samples from the two overdose cases were positive for PCP in all IAs evaluated. The commercial PCP IAs evaluated exhibited utility as rapid, preliminary screening techniques for 3-MeO-PCP and 4-MeO-PCP, but not for ketamine. The low reactivity of MXE limits its detectability in the PCP IAs evaluated.

35

Naghavi, Morteza, Albert A. Yen, Alex W. H. Lin, Hirofumi Tanaka, and Stanley Kleis. "New Indices of Endothelial Function Measured by Digital Thermal Monitoring of Vascular Reactivity: Data from 6084 Patients Registry." International Journal of Vascular Medicine 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/1348028.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Background. Endothelial function is viewed as a barometer of cardiovascular health and plays a central role in vascular reactivity. Several studies showed digital thermal monitoring (DTM) as a simple noninvasive method to measure vascular reactivity that is correlated with atherosclerosis risk factors and coronary artery disease. Objectives. To further evaluate the relations between patient characteristics and DTM indices in a large patient registry. Methods. DTM measures were correlated with age, sex, heart rate, and systolic and diastolic blood pressure in 6084 patients from 18 clinics. Results. DTM vascular reactivity index (VRI) was normally distributed and inversely correlated with age (r=-0.21, p<0.0001). Thirteen percent of VRI tests were categorized as poor vascular reactivity (VRI < 1.0), 70 percent as intermediate (1.0 ≤ VRI < 2.0), and 17 percent as good (VRI ≥ 2.0). Poor VRI (<1.0) was noted in 6% of <50 y, 10% of 50–70 y, and 18% of ≥70 y. In multiple linear regression analyses, age, sex, and diastolic blood pressure were significant but weak predictors of VRI. Conclusions. As the largest database of finger-based vascular reactivity measurement, this report adds to prior findings that VRI is a meaningful physiological marker and reflects a high level of residual risk found in patients currently under care.

36

Favaloro, Emmanuel J., Nick Moraitis, Jerry Koutts, Thomas Exner, and Kenneth F. Bradstock. "Endothelial Cells and Normal Circulating Haemopoietic Cells Share a Number of Surface Antigens." Thrombosis and Haemostasis 61, no. 02 (1989): 217–24. http://dx.doi.org/10.1055/s-0038-1646562.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

SummaryHuman endothelial cells, cultured from umbilical cord veins, have been evaluated for expression of a large number of cell surface antigens with known haemopoietic, particularly myeloid, cell distribution. This was achieved by evaluating endothelial reactivity (using non-fixed cells) with groups of monoclonal antibodies (MAB) belonging to distinct Clusters of Differentiation (CD), as defined by the Third International Workshop on Leukocyte Differentiation Antigens (ILWS). Results indicate that many antigens known to be present on haemopoietic cells, including those on platelets, are co-expressed on endothelial cells. The most intense degree of reactivity was seen using MAB to CD-9 and CD-13, although significant reactivity was also observed using MAB to CD-31 and CD-32. Data also suggests weak binding to endothelial cells of MAB belonging to CD-14, CD-15 and CD-16. A number of unclustered MAB reactive with haemopoietic antigens can also be shown to bind to endothelial cells.

37

Launois, Pascal, Annie Drowart, Eliane Bourreau, Pierre Couppie, Claire-Michèle Farber, Jean-Paul Van Vooren, and Kris Huygen. "T Cell Reactivity against Mycolyl Transferase Antigen 85 ofM. tuberculosisin HIV-TB Coinfected Subjects and in AIDS Patients Suffering from Tuberculosis and Nontuberculous Mycobacterial Infections." Clinical and Developmental Immunology 2011 (2011): 1–10. http://dx.doi.org/10.1155/2011/640309.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

The mycolyl transferase antigen 85 complex is a major secreted protein family from mycobacterial culture filtrate, demonstrating powerful T cell stimulatory properties in most HIV-negative, tuberculin-positive volunteers with latentM.tuberculosisinfection and only weak responses in HIV-negative tuberculosis patients. Here, we have analyzed T cell reactivity against PPD and Ag85 in HIV-infected individuals, without or with clinical symptoms of tuberculosis, and in AIDS patients with disease caused by nontuberculous mycobacteria. Whereas responses to PPD were not significantly different in HIV-negative and HIV-positive tuberculin-positive volunteers, responses to Ag85 were significantly decreased in the HIV-positive (CDC-A and CDC-B) group. Tuberculosis patients demonstrated low T cell reactivity against Ag85, irrespective of HIV infection, and finally AIDS patients suffering from NTM infections were completely nonreactive to Ag85. A one-year follow-up of twelve HIV-positive tuberculin-positive individuals indicated a decreased reactivity against Ag85 in patients developing clinical tuberculosis, highlighting the protective potential of this antigen.

38

Farrell, Anthony P., and Peter S. Davie. "Coronary artery reactivity in the mako shark, Isurus oxyrinchus." Canadian Journal of Zoology 69, no. 2 (February 1, 1991): 375–79. http://dx.doi.org/10.1139/z91-058.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Vasoactivity was examined in isolated vascular rings from the coronary arteries of the mako shark, Isurus oxyrinchus, a representative of the athletic elite among elasmobranch fishes. Adenosine relaxed vascular rings. ADP contracted vascular rings at concentrations less than 0.1 mM and relaxed them at higher concentrations. Theophylline inhibited both the ADP-mediated contraction and adenosine-mediated relaxation. Prostaglandin F2α produced strong constrictions. Serotonin had no vasoactive effect. Adrenaline and noradrenaline produced relaxations, indicating a population of β-adrenoceptors. ACh produced weak relaxations at concentrations greater than 10 μM. With the notable exception of the response to adenosine, these vasoactive responses were similar to those previously observed for the coronary arteries in another elasmobranch, the rough skate (Raja nasuta).

39

Liebmann, Jonathan M., Jennifer B. A. Muller, Dagmar Kubistin, Anja Claude, Robert Holla, Christian Plass-Dülmer, Jos Lelieveld, and John N. Crowley. "Direct measurements of NO<sub>3</sub> reactivity in and above the boundary layer of a mountaintop site: identification of reactive trace gases and comparison with OH reactivity." Atmospheric Chemistry and Physics 18, no. 16 (August 22, 2018): 12045–59. http://dx.doi.org/10.5194/acp-18-12045-2018.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Abstract. We present direct measurements of the summertime total reactivity of NO3 towards organic trace gases, kOTGNO3, at a rural mountain site (988 m a.s.l.) in southern Germany in 2017. The diel cycle of kOTGNO3 was strongly influenced by local meteorology with high reactivity observed during the day (values of up to 0.3 s−1) and values close to the detection limit (0.005 s−1) at night when the measurement site was in the residual layer and free troposphere. Daytime values of kOTGNO3 were sufficiently large that the loss of NO3 due to reaction with organic trace gases competed with its photolysis and reaction with NO. Within experimental uncertainty, monoterpenes and isoprene accounted for all of the measured NO3 reactivity. Averaged over the daylight hours, more than 25 % of NO3 was removed via reaction with biogenic volatile organic compounds (BVOCs), implying a significant daytime loss of NOx and the formation of organic nitrates due to NO3 chemistry. Ambient NO3 concentrations were measured on one night and were comparable to those derived from a stationary-state calculation using measured values of kOTGNO3. We present and compare the first simultaneous, direct reactivity measurements for the NO3 and OH radicals. The decoupling of the measurement site from ground-level emissions resulted in lower reactivity at night for both radicals, though the correlation between OH and NO3 reactivity was weak as would be anticipated given their divergent trends in rate constants with many organic trace gases.

40

Mercier, Bertrand, Di Yang, Ziyue Zhuang, and Jiajie Liang. "A simplified analysis of the Chernobyl accident." EPJ Nuclear Sciences & Technologies 7 (2021): 1. http://dx.doi.org/10.1051/epjn/2020021.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

We show with simplified numerical models, that for the kind of RBMK operated in Chernobyl: The core was unstable due to its large size and to its weak power counter-reaction coefficient, so that the power of the reactor was not easy to control even with an automatic system. Xenon oscillations could easily be activated. When there was xenon poisoning in the upper half of the core, the safety rods were designed in such a way that, at least initially, they were increasing (and not decreasing) the core reactivity. This reactivity increase has been sufficient to lead to a very high pressure increase in a significant amount of liquid water in the fuel channels thus inducing a strong propagating shock wave leading to a failure of half the pressure tubes at their junction with the drum separators. The depressurization phase (flash evaporation) following this failure has produced, after one second, a significant decrease of the water density in half the pressure tubes and then a strong reactivity accident due to the positive void effect reactivity coefficient. We evaluate the fission energy released by the accident

41

Finkel, Eli J., and Erica B. Slotter. "An I3 Theory analysis of human sex differences in aggression." Behavioral and Brain Sciences 32, no. 3-4 (August 2009): 279. http://dx.doi.org/10.1017/s0140525x09990410.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

AbstractAccording to I3 Theory, individuals enact aggressive behaviors when (a) instigating triggers are severe, (b) impelling forces are strong, and/or (c) inhibiting forces are weak. Archer's analysis of human sex differences in aggression could be bolstered by a careful analysis of male-female discrepancies in reactivity (or exposure) to instigating triggers, proneness toward impelling forces, and/or proneness toward inhibiting forces.

42

Behim, Mourd, Miloud Beddar, and Pierre Clastres. "Reactivity of Granulated Blast Furnace Slag." Slovak Journal of Civil Engineering 21, no. 2 (June 1, 2013): 7–14. http://dx.doi.org/10.2478/sjce-2013-0007.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Abstract The Algerian iron and steel complex of El Hadjar, near the city of Annaba, produces a granulated blast furnace slag (GBFS) mainly used by the local cement factories as an addition to clinker of up to 30 % as maximum content, for manufacturing a compound CEM II type cement (Algerian Standard). With the aim, on the one hand, of limiting the use of high clinker content in Algerian cement plants and replacing it with other constituents such as granulated blast furnace slag and, on the other hand, to use this slag as an addition to local concrete, we have attempted to characterize it according to its degree of reactivity. The use of chemical activity indexes and caustic soda tests lead to disappointing results that are contradicted by the results obtained on mortar within the scope of the standard determination of a hydraulic efficient index. The results obtained indicated that the classification of El Hadjer slag strongly depends on its degree of fineness; it also has weak short-term activity, denoting a slower kinetics of reaction compared to classical slag. These results permit us to recommend a minimal Blaine of 3500 cm2/g for this slag. A more intensive use of this slag in cement and concrete is undoubtedly possible, but this must be demonstrated by conducting tests on mortar and validating by a study on concrete.

43

Wachi, Naruhiko, Takeshi Kondo, Satoru Ito, Satoru Hiroto, Ji-Young Shin, and Hiroshi Shinokubo. "Synthesis, reactivity and property of 5,15-dithiaporphyrin copper(II) complex." Journal of Porphyrins and Phthalocyanines 18, no. 08n09 (August 2014): 675–78. http://dx.doi.org/10.1142/s1088424614500412.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Preparation of 5,15-dithiaporphyrin copper(II) complex was carried out by treatment of 5,15-dithiaporphyrin free-base with copper(II) acetate. X-ray diffraction analysis elucidated its dimeric structure in the solid state, in which the meso-sulfur atom served as an axial ligand to each pentacoordinated Cu ( II ) center. Temperature dependent magnetic susceptibility of the complex was measured to reveal the weak antiferromagnetic interaction between two Cu ( II ) centers in the solid state. 5,15-dithiaporphyrin Cu ( II ) complex was converted into 10-thiacorrole Cu ( II ) complex in good yield upon heating with triphenylphosphine in refluxing toluene.

44

Frostegård, J., C. Hellström, P. Nilsson, A. G. Frostegård, and S. Ajeganova. "Autoantibody profiling reveals four protein candidate autoantigens associated with systemic lupus erythematosus." Lupus 27, no. 10 (July 24, 2018): 1670–78. http://dx.doi.org/10.1177/0961203318788153.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Objectives In systemic lupus erythematosus (SLE) there are typically many autoantibodies. The disease heterogeneity could be better understood with discovery of phenotype-specific antigens targeted by autoantibodies. We here aimed to identify novel autoantigens potentially related to SLE disease and a major complication, atherosclerosis. Methods Antigen microarrays were used to profile IgG autoantibody reactivity against 77 protein fragments (20–140 amino acids (aa) long, median 89 aa) produced within the Human Protein Atlas project, in serum samples from SLE patients ( n = 107) and age- and sex-matched population-based controls ( n = 107). Common carotid intima-media thickness, plaque occurrence and echogenicity were determined by B-mode ultrasound. Results We determined significant differences between patients and controls in IgG reactivity against four proteins. In patients compared to controls, there was an increase of IgG reactivity against zinc finger protein 688 (ZNF688), early B cell factor 2 (EBF2), crystallin, alpha B (CRYAB) and tumor necrosis factor receptor superfamily member 13C (TNFRSF13C). Of these four antigens, only anti-ZNF688 was associated with carotid atherosclerosis (plaque occurrence) and vulnerable plaques in SLE. There was a weak association between anti-EBF2 and SLE disease activity but no significant associations were determined for other measured IgG reactivity. Conclusions In this discovery screening we here demonstrate new candidate autoantigens with differential reactivity (reflecting autoantibody levels) in SLE patients and in controls and in relation to atherosclerosis in SLE.

45

Yao, Jiong, and Ronald F. Evilia. "Deuteration of Extremely Weak Organic Acids by Enhanced Acid-Base Reactivity in Supercritical Deuteroxide Solution." Journal of the American Chemical Society 116, no. 25 (December 1994): 11229–33. http://dx.doi.org/10.1021/ja00104a003.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

46

Hososhima, Shoko, Shunta Shigemura, Hideki Kandori, and Satoshi P. Tsunoda. "Novel optogenetics tool: Gt_CCR4, a light-gated cation channel with high reactivity to weak light." Biophysical Reviews 12, no. 2 (March 12, 2020): 453–59. http://dx.doi.org/10.1007/s12551-020-00676-7.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

47

Rother, S., S. Kollrich, K. Borns, J. Klempnauer, and R. Schwinzer. "Altered CD161 Reactivity Triggers and Enhances Activation of Cytotoxic NK Cells Following Weak Receptor Stimulation." Transplantation 98 (July 2014): 316–17. http://dx.doi.org/10.1097/00007890-201407151-01004.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

48

Chan, Michael C W. "Weak Attractive Ligand–Polymer and Related Interactions in Catalysis and Reactivity: Impact, Applications, and Modeling." Chemistry – An Asian Journal 3, no. 1 (January 4, 2008): 18–27. http://dx.doi.org/10.1002/asia.200700226.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

49

Salisbury, Brian A., John F. Young, Glenn P. A. Yap, and Klaus H. Theopold. "Synthesis and Reactivity of Pyrrolide-Diimine Complexes of Chromium." Collection of Czechoslovak Chemical Communications 72, no. 5-6 (2007): 637–48. http://dx.doi.org/10.1135/cccc20070637.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

Lithium 2,5-bis{[(2,6-diisopropylphenyl)imino]methyl}pyrrol-1-ide (LiL) reacts with [CrCl3(thf)3] to yield the octahedral complex [(η2-L)CrCl2(thf)2] (1), in which only two of the three potential nitrogen donors are coordinated to chromium. In the presence of various alkyl aluminum cocatalysts, 1 catalyzes the polymerization of ethylene. Attempts to prepare alkyl derivatives of 1 were thwarted by an apparent disproportionation, yielding divalent [(η2-L)(η1-L)Cr(thf)] (2). The molecular structures of 1 and 2 have been determined by X-ray diffraction. The structure of 2 is unusual in that it features weak, but equivalent interactions of both imine groups of the η1-pyrrolide ligands with the chromium, giving rise to an approximately octahedral coordination geometry with two extremely long Cr-N distances.

50

Sundström, B. E., W. B. Nathrath, and T. I. Stigbrand. "Diversity in immunoreactivity of tumor-derived cytokeratin monoclonal antibodies." Journal of Histochemistry & Cytochemistry 37, no. 12 (December 1989): 1845–54. http://dx.doi.org/10.1177/37.12.2479674.

Повний текст джерела

Стилі APA, Harvard, Vancouver, ISO та ін.

Анотація:

The cytokeratins 8, 18, and 19, expressed in many normal and malignant epithelial cells, were purified from human gastrointestinal tumors and used as immunogen for hybridoma generation. The reactivity pattern of five of the generated ten monoclonal antibodies (MAb) was characterized biochemically and immunohistochemically. All of the generated MAb were reactive with the central rod portion of the cytokeratins, as determined after partial enzymatic degradation, and displayed characteristic reactivity patterns. MAb TS 4 exhibits pan-epithelial immunohistochemical reactivity staining of all epithelial structures, including all layers of epidermis and non-keratinizing squamous epithelium and myoepithelial cells. The determinant involved is present on several different cytokeratins, i.e., nos. 1, 5, 7, 8, and 15, as determined by immunoblotting experiments from different tissues and cell lines. MAb TS 1, TS 3, and TS 7 reveal pluri-epithelial reactivity pattern immunohistochemically, similar to TS 4, but they are unreactive with whole epidermis and with superficial cell layers of non-keratinizing squamous cells. MAb TS 1 was found to be highly specific and reactive only with cytokeratin 8. Furthermore, the TS 1 MAb alone can precipitate the antigen, indicating reactivity with repetitive epitopes on cytokeratin 8. MAb TS 3 and 7 bind to cytokeratins 7 and 8. Finally, MAb TS 8 was found to be immunohistologically the most restricted, in general lacking reactivity to hepatocytes, pancreatic and salivary gland acinar cells, proximal renal tubules, and luminal cells of the epididymis. TS 8 was mainly reactive with cytokeratin 19 and showed weak binding to cytokeratin 8 and 14.

Статті в журналах з теми "Weak reactivity"

Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями