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Статті в журналах з теми "Warfarin dosage"
Lala, Mallika, Gilbert J. Burckart, Cheryl M. Takao, Vera Pravica, Jeremiah D. Momper, and Jogarao V. S. Gobburu. "Genetics-Based Pediatric Warfarin Dosage Regimen Derived Using Pharmacometric Bridging." Journal of Pediatric Pharmacology and Therapeutics 18, no. 3 (September 1, 2013): 209–19. http://dx.doi.org/10.5863/1551-6776-18.3.209.
Повний текст джерелаRecker, Mark W., and Karen L. Kier. "Potential Interaction between Clarithromycin and Warfarin." Annals of Pharmacotherapy 31, no. 9 (September 1997): 996–98. http://dx.doi.org/10.1177/106002809703100907.
Повний текст джерелаZatuchni, Jacob. "Guidelines for Warfarin Dosage." Drug Intelligence & Clinical Pharmacy 22, no. 10 (October 1988): 825–26. http://dx.doi.org/10.1177/106002808802201022.
Повний текст джерелаLiu, Hong-Qiang, Chang-Po Zhang, Chang-Zhen Zhang, Xiang-Chen Liu, and Zun-Jing Liu. "Influence of Two Common Polymorphisms in theEPHX1Gene on Warfarin Maintenance Dosage: A Meta-Analysis." BioMed Research International 2015 (2015): 1–12. http://dx.doi.org/10.1155/2015/564149.
Повний текст джерелаKim, Karissa Y., and Michael A. Mancano. "Fenofibrate Potentiates Warfarin Effects." Annals of Pharmacotherapy 37, no. 2 (February 2003): 212–15. http://dx.doi.org/10.1177/106002800303700210.
Повний текст джерелаDang, Mai-Trang N., Julie Hambleton, and Steven R. Kayser. "The Influence of Ethnicity on Warfarin Dosage Requirement." Annals of Pharmacotherapy 39, no. 6 (June 2005): 1008–12. http://dx.doi.org/10.1345/aph.1e566.
Повний текст джерелаMüller, C. R., S. Rost, M. Watzka, C. G. Bevans, and J. Oldenburg. "Comparative genetics of warfarin resistance." Hämostaseologie 34, no. 02 (2014): 143–59. http://dx.doi.org/10.5482/hamo-13-09-0047.
Повний текст джерелаAbsher, Randall K., M. Elisabeth Moore, and Mary H. Parker. "Patient-Specific Factors Predictive of Warfarin Dosage Requirements." Annals of Pharmacotherapy 36, no. 10 (October 2002): 1512–17. http://dx.doi.org/10.1345/aph.1c025.
Повний текст джерелаZhu, Yusheng, Michael Shennan, Kristen K. Reynolds, Nancy A. Johnson, Matthew R. Herrnberger, Roland Valdes, and Mark W. Linder. "Estimation of Warfarin Maintenance Dose Based on VKORC1 (−1639 G>A) and CYP2C9 Genotypes." Clinical Chemistry 53, no. 7 (July 1, 2007): 1199–205. http://dx.doi.org/10.1373/clinchem.2006.078139.
Повний текст джерелаEdwards, Clive, Timothy Butler, Hilary Wynne, and Farhad Kamali. "The Influence of (R)- and (S)-Warfarin, Vitamin K and Vitamin K Epoxide upon Warfarin Anticoagulation." Thrombosis and Haemostasis 84, no. 07 (2000): 39–42. http://dx.doi.org/10.1055/s-0037-1613964.
Повний текст джерелаДисертації з теми "Warfarin dosage"
Ibrahim, Saied. "Investigating methods of improving the safety of oral anticoagulation with computer assisted dosage and standardisation of the International Normalised Ratio." Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/investigating-methods-of-improving-the-safety-of-oral-anticoagulation-with-computer-assisted-dosage-and-standardisation-of-the-international-normalised-ratio(a51f3881-e55b-4b99-abba-6d2c6cfe7564).html.
Повний текст джерелаEriksson, Niclas. "On the Prediction of Warfarin Dose." Doctoral thesis, Uppsala universitet, Klinisk farmakologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-172864.
Повний текст джерелаKing, Barry Philip. "Genetic factors affecting warfarin dose requirements and clearance." Thesis, University of Newcastle Upon Tyne, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417716.
Повний текст джерелаHamberg, Anna-Karin. "Pharmacometric Models for Individualisation of Warfarin in Adults and Children." Doctoral thesis, Uppsala universitet, Klinisk farmakogenomik och osteoporos, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-197599.
Повний текст джерелаMajeed, Habeeb. "Supplementation to Improve Anticoagulation Control with Low Dose Vitamin K as an Adjuvant to Warfarin Therapy: A Double-blind, Placebo-controlled Randomized Controlled Trial." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/23237.
Повний текст джерелаMakambwa, Edson. "The role of warfarin pharmacogenomics on the time it takes to reach stable therapeutic International Normalized Ratio (INR) and on warfarin dose required to maintain stable therapeutic INR in Black African and Mixed Ancestry South Africans: a focus on CYP2C9 and VKORC1." Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/31178.
Повний текст джерелаTai, Chuntien, and 戴俊典. "A Research of Data Mining in Warfarin Dosage Decisions." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/12554411984456215497.
Повний текст джерела國立中正大學
資訊管理學系暨研究所
99
Drug safety has become one of the most critical indicators in patient safety. In recent years, the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) has paid considerable attention to the safety of anticoagulant administration. Among all anticoagulants, Warfarin has long been listed among the top ten drugs causing adverse drug events (ADE). This paper investigates a number of supervised learning techniques, including artificial neural network (ANN), model tree (M5), support vector machines (SVM), and k-nearest neighbors (kNN), to construct a Warfarin dosage prediction model. To achieve higher prediction accuracy, we further consider both Bagging algorithms and ensemble classifiers in experimental evaluation. For performance evaluation, the initial dose of Warfarin prescribed by clinicians is established as the baseline of our study. The experimental data collection consists of complete historical records of 587 inpatients who received Warfarin treatment. The overall evaluation results show that all of the learning based systems are significantly more accurate than the baseline. Among all prediction models, Bagging VOTE with four classifiers is suggested as the most effective prediction model due to its lower mean absolute errors (MAE) and variation of errors. The investigated models can not only facilitate clinicians in dosage decision-making, but also help reduce patient risk from adverse drug events.
Wu, Meng-Lin, and 吳孟霖. "The Association of Warfarin Dosage in Clinical Use and Pharmacogenomics." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/05321073967456502525.
Повний текст джерела國立臺灣大學
藥學研究所
94
Background Warfarin is an anticoagulant that is prescribed widely for the treatment and prevention of thrombosis. However, risks caused by warfarin vary, depending on the individuals, mainly genetic variations, environment, diseases and the severity of disease. It is important to adjust the dose of warfarin in clinical use based on the International Normalized Ratio (INR) value monitoring. All the possible factors involving dose adjustment will be investigated in this study in order to approach the individualized drug use. Methods Outpatients receiving long-term therapy were enrolled in National Taiwan University Hospital from July to October 2005. We collected the data including sex, age, indication, concomitant agents, INR value and the genotype of certain SNP sites in CYP1A2, CYP2C9, CYP2C19, CYP3A4, coagulation factor II, factor VII, factor IX, factor X, protein C, protein S, EPHX1, GGCX, GSTA1 and VKORC1. Furthermore, we detected the concentration of warfarin enantiomers and studied the association of pharmacogenomics and personalized warfarin doses. Results There were 75 patients enrolled in the study but two were excluded due to the failure of identifying the genotype. Deep vein thrombosis is the main indication in all patients. The mean maintenance dose was 3.9 mg/day and the mean INR value was 2.02. Results showed the variants of the positions -1639, 1173, 2225 in VKORC1 and the position 681 in CYP2C19 were highly related with warfarin maintenance dose. Also, there was negative relationship between age and warfarin maintenance dose in our study. Linkage disequilibrium of factor IX, GGCX and VKORC1 in certain SNP sites occurred in the study. The concentration of enantiomers was positively related to the maintenance dose of warfarin, but not to drug response. It is not applicable to adjustment of the dose by monitoring the concentration of racemic warfarin, or to its enantiomers. Conclusion The maintenance dose of warfarin was determined by multiple factors. The ethnic effect of Taiwanese and Caucasian might be partly caused by the different frequency of SNP sites of VKORC1 and CYP2C19. According to the regression model, we can calculate the warfarin maintenance dose by age and the genotype of these SNP sites so as to decrease the adverse drug effects and increase the safety of the drug.
Wang, An-Li, and 王安利. "A Research of Generalized Linear Model in Warfarin Dosage Decisions." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/04559429061938288386.
Повний текст джерела臺北市立大學
數學系數學教育碩士班統計組
102
Warfarin is the anti-coagulation and it is irreplaceable. Warfarin dose is affected by many factors, such as related drugs and diseases. Using warfarin has to be careful. If patients take inadequate doses, they will be blood clots. On the other hand, if patients take excessive doses, they will be bleeding. Currently, we refer to warfarin-used guide for Europeans and Americans in Taiwan, and there are few domestic papers about warfarin dose. In addition, it has not published a study of warfarin dose which is based on Chinese case history. Therefore, this research in warfarin dose is based on case history of patints who used warfarin in a perid in a large hospital. This data is composed of 87 patints, including 45 females and 42 males. Each patient getting warfarin prescription is counted as one sample, and the data amounts to 415 samples comprisig age, INR, related drugs and related diseases. Thence, it is a repeat measurement data, so using generalized estimating equations (GEE) to estimate warfarin dose in each case. The GEE results are found that (1) all related diseases we selected reduced dose about 0.1mg, (2) related drugs bring about 0.1mg of adjustment in dose at least. (3)As other conditions remain unchanged, the INR rise 1 degree, the average of warfarin dose takes more about 0.27mg - 0.28mg.
Mitchell, Cathrine. "Evaluation of CYP2C9 and VKORC1 gene variants that may result in warfarin dosage sensitivity and poor pregnancy outcomes." Thesis, 2008. http://hdl.handle.net/10539/5757.
Повний текст джерелаКниги з теми "Warfarin dosage"
J, Newton George, Inhalation Toxicology Research Institute, Sandia National Laboratories, and United States. Dept. of Energy, eds. Human radiation exposures related to nuclear weapons industries. Albuquerque, NM: Inhalation Toxicology Research Institute, Lovelace Biomedical and Environmental Research Institute, 1985.
Знайти повний текст джерелаRajakaruna, Senerat. A mathematical prediction of warfarin maintenance dosage. Bradford, 1987.
Знайти повний текст джерелаScott, Julie. The implementation and evaluation of a warfarin dosage protocol in orthopedic surgery patients. 2000.
Знайти повний текст джерелаMcDonald, Vickie, and Marie Scully. Anticoagulants and antithrombotics in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0051.
Повний текст джерелаKilkelly, Shannon. Coagulation System. Edited by Matthew D. McEvoy and Cory M. Furse. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190226459.003.0090.
Повний текст джерелаMedicine, Institute of. An Evaluation of Radiation Exposure Guidance for Military Operations: Interim Report (Compass Series). National Academies Press, 1997.
Знайти повний текст джерела1945-, Mettler Fred A., Johnson J. Christopher, Thaul Susan, and Institute of Medicine (U.S.). Committee on Battlefield Radiation Exposure Criteria., eds. An evaluation of radiation exposure guidance for military operations: Interim report. Washington, D.C: National Academy Press, 1997.
Знайти повний текст джерела(US), National Research Council. Exposure of the American Population to Radioactive Fallout from Nuclear Weapons Tests: A Review of the CDC-NCI Draft Report on a Feasibility Study of the ... by the United States and Other Nations. National Academies Press, 2003.
Знайти повний текст джерелаNational Research Council (U.S.). Committee to Review the CDC-NCI Feasibility Study of the Health Consequences from Nuclear Weapons Tests, ed. Exposure of the American population to radioactive fallout from nuclear weapons tests: A review of the CDC-NCI draft report on a feasibility study of the health consequences to the American population from nuclear weapons tests conducted by the United States and other nations. Washington, D.C: National Academies Press, 2003.
Знайти повний текст джерелаЧастини книг з теми "Warfarin dosage"
Wessler, Stanford. "What’s the Dose?" In The New Dimensions of Warfarin Prophylaxis, 149–52. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4757-5985-3_11.
Повний текст джерелаTao, Yanyun, Dan Xiang, Yuzhen Zhang, and Bin Jiang. "Swarm ANN/SVR-Based Modeling Method for Warfarin Dose Prediction in Chinese." In Lecture Notes in Computer Science, 351–58. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-61833-3_37.
Повний текст джерелаKang, Joonghee, Masato Sakon, and Jun-Ichi Kambayashi. "Reevaluation of Effectiveness of Low-Dose Warfarin as Antithrombotic Therapy After Vascular Reconstruction." In Modern Vascular Surgery, 424–29. New York, NY: Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2632-1_42.
Повний текст джерелаYang, Lu, and Mark W. Linder. "Development of Predictive Models for Estimating Warfarin Maintenance Dose Based on Genetic and Clinical Factors." In Methods in Molecular Biology, 337–44. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-435-7_22.
Повний текст джерелаKapoor, Indu, Charu Mahajan, and Hemanshu Prabhakar. "Anesthesia in a Patient on Anticoagulant Dabigatran Presenting for Emergency Surgery." In Anesthesiology: A Problem-Based Learning Approach, edited by Tracey Straker and Shobana Rajan, 315–19. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190850692.003.0036.
Повний текст джерелаEzekowitz, Michael D., and Amanulla N. Khaji. "Stroke prevention in atrial fibrillation." In ESC CardioMed, 2185–95. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0514.
Повний текст джерела"Alterations to Warfarin Dose Maintenance Therapy." In Peripheral Brain for the Pharmacist, 2016 - 17. 2215 Constitution Avenue, NW, Washington, DC 20037-2985: The American Pharmacists Association, 2015. http://dx.doi.org/10.21019/9781582122403.ch7.
Повний текст джерела"Alterations to Warfarin Dose Maintenance Therapy." In Peripheral Brain for the Pharmacist, 2017 - 18. 2215 Constitution Avenue, N.W. Washington, DC 20037-2985: The American Pharmacists Association, 2017. http://dx.doi.org/10.21019/9781582122885.warfarindosemaintenace.
Повний текст джерела"Alterations to Warfarin Dose Maintenance Therapy (2 cards)." In Peripheral Brain for the Pharmacist, 2018 - 19. 2215 Constitution Avenue, N.W. Washington, DC 20037-2985: The American Pharmacists Association, 2018. http://dx.doi.org/10.21019/9781582123028.warfarindosemaintenace.
Повний текст джерелаAndreotti, Felicita, Eliano Pio Navarese, and Filippo Crea. "The NOACs in special situations: the elderly, renal impairment, combination with antiplatelet agents and thrombolytics." In ESC CardioMed, edited by Raffaele DeCaterina, 273–78. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0057.
Повний текст джерелаТези доповідей конференцій з теми "Warfarin dosage"
Crow, M. J., A. B. Latif, A. I. Critchley, C. Stainton, P. Nealon, and S. M. Rajah. "COMPUTER PREDICTION OF ANTICOAGULATION STATUS AND WARFARIN DOSE FOLLOWING CARDIAC SURGERY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643275.
Повний текст джерелаAltay, Osman, Mustafa Ulas, Mahmut OZER, and Ece GENC. "An Expert System to Predict Warfarin Dosage in Turkish Patients Depending on Genetic and Non-Genetic Factors." In 2019 7th International Symposium on Digital Forensics and Security (ISDFS). IEEE, 2019. http://dx.doi.org/10.1109/isdfs.2019.8757526.
Повний текст джерелаSaeeda, Hina, and Muhammad Adil Abid. "An Ideology for the Prediction of Critical Haplotype Blocks of Variants in Genes (Cyp2c9 And Vkorc1) for Warfarin (Anticoagulant) Drug Dosage to Treat Heart Patients Efficiently by Using Ml (Machine Learning) and Data Stream Mining Techniques." In ICAIP 2019: 2019 3rd International Conference on Advances in Image Processing. New York, NY, USA: ACM, 2019. http://dx.doi.org/10.1145/3373419.3373424.
Повний текст джерелаMcKernan, A., J. M. Thomson, and L. Poller. "A PROSPECTIVE RANDOMISED CONTROLLED STUDY OF MINI-DOSE WARFARIN PROPHYLAXIS OF DEEP VEIN THROMBOSIS IN MAJOR SURGERY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643879.
Повний текст джерелаPowers, P. J., M. Gent, R. Jay, J. Hirsh, M. Levine, and G. Turpie. "DEEP VEIN THROMBOSIS PROPHYLAXIS IN SURGICALLY TREATED FRACTURED HIP PATIENTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643692.
Повний текст джерелаWang, Zeyuan, Josiah Poon, Jie Yang, and Simon Poon. "Warfarin Dose Estimation on High-dimensional and Incomplete Data." In Hawaii International Conference on System Sciences. Hawaii International Conference on System Sciences, 2021. http://dx.doi.org/10.24251/hicss.2021.419.
Повний текст джерелаGerna, M., and M. B. Donati. "HYPERCOAGULABILITY AND REDUCED SENSITIVITY TO WARFARIN IN RATS FOLLOWING CAFFEINE INTAKE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643399.
Повний текст джерелаTao, Yanyun, Yuzhen Zhang, and Bin Jiang. "Evolutionary learning-based modeling for warfarin dose prediction in Chinese." In GECCO '17: Genetic and Evolutionary Computation Conference. New York, NY, USA: ACM, 2017. http://dx.doi.org/10.1145/3067695.3082492.
Повний текст джерелаKarpurapu, Anish, Adam Krekorian, Ye Tian, Leslie M. Collins, Ravi Karra, Aaron D. Franklin, and Boyla O. Mainsah. "Evaluating the Effect of Longitudinal Dose and INR Data on Maintenance Warfarin Dose Predictions." In 2021 IEEE EMBS International Conference on Biomedical and Health Informatics (BHI). IEEE, 2021. http://dx.doi.org/10.1109/bhi50953.2021.9508510.
Повний текст джерелаRackauskiene, Jolita, Vaida Gedvilaite, Mindaugas Mataciunas, Mazvile Abrutyte, Olga Kusner, and Edvardas Danila. "Therapeutic warfarin dose dependence on age and smoking in acute pulmonary embolism." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa700.
Повний текст джерелаЗвіти організацій з теми "Warfarin dosage"
Oh, SangHyeon, Seoyong Choi, and Jee-Eun Chung. Comparative efficacy and safety of reduced dose of DOACs in patients with atrial fibrillation. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2022. http://dx.doi.org/10.37766/inplasy2022.8.0073.
Повний текст джерела