Добірка наукової літератури з теми "Vésicule membranaire"
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Статті в журналах з теми "Vésicule membranaire"
Ghossoub, Rania, Raphael Leblanc, Guido David, and Pascale Zimmermann. "Tétraspanines et syndécanes." médecine/sciences 37, no. 12 (December 2021): 1101–7. http://dx.doi.org/10.1051/medsci/2021202.
Повний текст джерелаBlandin, Alexia, and Soazig Le Lay. "Vésicules extracellulaires et maladies métaboliques." médecine/sciences 37, no. 12 (December 2021): 1125–32. http://dx.doi.org/10.1051/medsci/2021209.
Повний текст джерелаLotteau, V. "Des récepteurs membranaires définissent la spécificité du transport des vésicules." médecine/sciences 9, no. 6-7 (1993): 802. http://dx.doi.org/10.4267/10608/2996.
Повний текст джерелаBéliveau, R. "Vésicules membranaires purifiées : un outil d'étude de la réabsorption rénale." médecine/sciences 3, no. 10 (1987): 589. http://dx.doi.org/10.4267/10608/3611.
Повний текст джерелаMercier, Vincent, Jorge Larios, Guillaume Molinard, Antoine Goujon, Stefan Matile, Aurélien Roux, and Jean Gruenberg. "La formation des vésicules intraluminales de l’endosome est contrôlée par la tension membranaire." médecine/sciences 37, no. 8-9 (August 2021): 697–700. http://dx.doi.org/10.1051/medsci/2021096.
Повний текст джерелаPodbilewicz, Benjamin. "Membrane fusion as a morphogenetic force in nematode development." Nematology 2, no. 1 (2000): 99–111. http://dx.doi.org/10.1163/156854100508818.
Повний текст джерелаДисертації з теми "Vésicule membranaire"
Pansu, Robert. "Photochimie dans les membranes synthétiques de chlorure de di-octadecyl, di-méthyl ammonium (DODAC) : la vésicule de DODAC, mythe ou réalité ?" Paris 11, 1988. http://www.theses.fr/1988PA112122.
Повний текст джерелаCastagnos, Pauline. "Vésicules catanioniques : design et mécanismes de délivrance de principes actifs." Toulouse 3, 2011. http://thesesups.ups-tlse.fr/1412/.
Повний текст джерелаSugar-derived catanionic surfactants self-assemble spontaneously into vesicles, which can encapsulate either hydrophilic drugs inside their aqueous core or hydrophobic and amphiphilic drugs inside their bilayer. Their biocompatibility, as well as their stability under time and dilution in biological media, allow to consider the use of these organized molecular systems for drug vectorization and delivery. In the present work, a mechanistic study showed these eco-designed and adjustable systems are able to fuse spontaneously with lipid assemblies mimicking cell membranes, provided that these latter present organization defects inside the bilayer. Cellular interaction mechanisms of such supramolecular systems were elucidated on cancer cell lines, by confocal microcopy and flow cytometry techniques. On the one hand, macropinocytosis, clathrin and caveolae pathways were shown to intervene as major active processes of cellular uptake of vesicles. The simultaneous intervention of these three pathways of endocytosis enables a progressive drug release through complementary mechanisms. On the other hand, experimental results verified that catanionic vesicles are capable of fusing with cell membranes. This spontaneous membrane fusion, concomitant with endocytosis, provides to these innovative systems the ability to deliver hydrophilic compounds directly inside cytoplasm. Numerous perspectives of such systems can thus be foreseen. An application towards vectorization of photosensible drugs was initiated in the present work, in order to fight cutaneous cancer through photodynamic therapy. These vectors, charged with hydrophobic active principles, showed enhanced stability and promising in vitro results for treatment of skin melanoma and oral squamous carcinoma
Silva, Rosa da Luz Brenda. "Caractérisation des vésicules extracellulaires dérivées de staphylococcus aureus et leur impact sur la réponse de l'hôte." Electronic Thesis or Diss., Rennes, Agrocampus Ouest, 2022. http://www.theses.fr/2022NSARB361.
Повний текст джерелаBacterial extracellular vesicles (EVs) are nanoparticles carrying macromolecules that can influence host-pathogen interactions. The pathogen Staphylococcus aureus (SA) releases EVs whose characteristics are still largely explored. This thesis’s project provides the first work extensively characterizing the RNA and protein content of profile of SA clinical HG003 strain and its producing cells. We found that EVs comprised all RNA classes including small regulatory RNA. The protein content of EVs was also diverse with various important elements such as virulence factors, transcriptional regulators, and metabolic enzymes. Interestingly, the protein and RNA content of EVs differed from that of its producing cells, suggesting that selective cargo packing exists. The intra- and interspecies role of EVs was also investigated.We found that the addition of HG003 EVs to bacterial cultures improved their growth in restrictive media. In the context of host-pathogen interactions, the cellular response induced by EVs differed from that induced by the living bacteria in both human and bovine models, indicating that EVs could display other physiological functions than those of bacteria which may be important to the infection process. Overall, our data evidence that SA EVs carry important newly discovered elements, and modulate the host response with different intensities, exposure periods, and by different routes from that of live bacteria. This study brings new knowledge about SA EVs potential functional roles in the context of bacterial physiology and staphylococcal infections
Kremer, Sébastien. "Extrusion de nanotubes membranaires : de la vésicule à la cellule vivante." Paris 6, 2009. http://www.theses.fr/2009PA066066.
Повний текст джерелаBorghi, Nicolas. "Nanotubes membranaires : extrusion hydrodynamique." Paris 6, 2006. http://www.theses.fr/2006PA066556.
Повний текст джерелаSolon, Jérôme. "Interactions entre membranes lipidiques chargées : instabilités, déformations et mouvement." Paris 6, 2004. http://www.theses.fr/2004PA066580.
Повний текст джерелаL'Heureux, Gaétan. "Utilisation de sondes fluorescentes dans la caractérisation des vésicules lipidiques : application au transfert d'énergie membranaire." Thèse, Université du Québec à Trois-Rivières, 1990. http://depot-e.uqtr.ca/6783/1/000583341.pdf.
Повний текст джерелаGaudin, Marie. "Etude des vésicules membranaires produites par les Archées hyperthermophiles marines de l'ordre des Thermococcales." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00716699.
Повний текст джерелаGaudin, Marie. "Etude des vésicules membranaires produites par les Archées hyperthermophiles marines de l’ordre des Thermococcales." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA112093/document.
Повний текст джерелаSecretion of membrane vesicles (MVs) is an important physiological process that has been extensively studied in Bacteria and Eukarya. The recent discovery that Archaea produce MVs shows that this process is universal and suggests that the Last Universal Common Ancestor, LUCA, certainly produced MVs. As these archaeal MVs have been only studied in some Crenarchaeota (ex: G/ Sulfolobus), we started characterizing MVs produced by Thermococcales, a group of hyperthermophilic anaerobic Euryarchaeota.In the first part of this study we examined the mechanism of production as well as the protein and lipid composition of MVs produced by three strains of Thermococcales: Thermococcus kodakaraensis, Thermococcus gammatolerans and Thermocococus sp. 5-4. We observed that MVs are released by a budding process from the cell envelope that is similar to ectosome formation in eukaryotic cells. Moreover, clusters of MVs often form filamentous structures and protuberances on cell surfaces, resembling recently described bacterial nanopods. Differences in structure are observable between MVs of the three species, as well as in their protein composition. However, MVs and cell membranes from the same species have a quite similar protein and lipid composition, confirming that MVs are produced from cell membranes. A major protein present in cell membranes and MVs from the three strains is the oligopeptide-binding proteins (OppA), which has homologues in MVs from Sulfolobus species. Thermococcales MVs harbor DNA and protect this DNA against thermodegradation. Here, we show that T. kodakaraensis cells transformed with the shuttle plasmid pLC70 release MVs harboring this plasmid. Interestingly, these MVs can be used to transfer pLC70 into plasmid-free cells, suggesting that MVs could be involved in DNA transfer between cells at high temperature. In the second part of this study, we were specially interested in the strain Thermococcus nautilus, a Thermococcale that produces MVs selectively enriched in two plasmids from the cell. Notably, one of them corresponds to the genome of a defective virus from PRD1-adenovirus lineage. This indicates that MVs can be used as vehicles for the transport of viral genomes and suggests that production of MVs by ancestral cells could have played a role in the origin of viruses.In addition to be involved in transport of plasmids/viruses, MVs from T. nautilus display a toxic effect on some strains of Thermococcales, maybe due to the delivery of toxins. Even if these “thermococcins” remain to be characterized, this is the first time that a toxic activity associated with MVs has been shown in Thermococcales
Dilda, Pierre. "Caractérisation de CFTR dans des vésicules membranaires purifiées a partir d'épithélium de trachée bovine : approche pharmacologique." Paris 5, 1995. http://www.theses.fr/1994PA05CD08.
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