Дисертації з теми "Typhoid and paratyphoid fever"
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Britto, Carl D. "The molecular epidemiology of paediatric enteric fever in Nepal between 2008 and 2016, and South India between 2016 and 2017." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:b58d6ae6-ba7d-4277-ba8a-8cf84dd56455.
Повний текст джерелаArjyal, Amit. "Clinical studies on enteric fever." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:7b82ceef-96de-4159-adcf-a06dc14c581a.
Повний текст джерелаWaddington, Claire Shelley. "Understanding typhoid disease : a controlled human infection model of typhoid fever." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:679ef7ec-b871-47a8-adea-d3fb3478e4b9.
Повний текст джерелаTsang, Shiu-wah Raymond. "An immunochemical and serological study of the surface antigens of Salmonella typhi /." [Hong Kong : University of Hong Kong], 1987. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12345933.
Повний текст джерелаHampton, Margaret. "Typhoid fever in colonial Toowoomba and Brisbane." University of Southern Queensland, Faculty of Arts, 2005. http://eprints.usq.edu.au/archive/00001435/.
Повний текст джерелаHue, Nguyen Thi. "The host genetics of typhoid fever in Vietnam." Thesis, Open University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486508.
Повний текст джерелаHouse, Deborah Louise. "Immune studies in patients with typhoid fever from Vietnam." Thesis, Imperial College London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396026.
Повний текст джерелаParry, Christopher M. "The treatment of multidrug resistant typhoid fever in Vietnam." Thesis, Open University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422008.
Повний текст джерелаPulickal, Anoop Sebastian. "Kinetics of natural and acquired immunity to typhoid fever." Thesis, University of Oxford, 2008. http://ora.ox.ac.uk/objects/uuid:335b4dd5-ab34-4bb0-8841-89476fc0855d.
Повний текст джерелаTsang, Shiu-wah Raymond, and 曾肇華. "An immunochemical and serological study of the surface antigens of Salmonella typhi." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1987. http://hub.hku.hk/bib/B31230994.
Повний текст джерелаOchiai, Rion Leon. "Control of typhoid fever : evaluating herd protection through public health use of typhoid VI polysaccharide vaccine." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:a6c8fa2f-66c7-46d8-9640-f1ebe3070113.
Повний текст джерелаMaharjan, Sabina. "Antimicrobial resistance and gallbladder carriage of Salmonella Typhi and Salmonella Paratyphi A in Kathmandu, Nepal." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:f303e4c4-90c9-4e50-be8e-682ac1e38512.
Повний текст джерелаKarkey, Abhilasha. "Evaluation of strain circulation and the epidemiology of enteric fever caused." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:ed1b578e-1589-46dc-9de4-20f2d1593fbc.
Повний текст джерелаPierce, Gerald J. "Public and private voices : the typhoid fever experience at Camp Thomas, 1898 /." unrestricted, 2007. http://etd.gsu.edu/theses/available/etd-11192007-161527/.
Повний текст джерелаTitle from file title page. Wendy H. Venet, committee chair; Stuart Galishoff, Charles G. Steffen, committee members. Electronic text (338 p.) : digital, PDF file. Description based on contents viewed Feb. 4, 2008. Includes bibliographical references (p. 308-338).
Pierce, Gerald Joseph. "Public and Private Voices: The Typhoid Fever Experience at Camp Thomas, 1898." Digital Archive @ GSU, 2007. http://digitalarchive.gsu.edu/history_diss/7.
Повний текст джерелаCromwell, Natasha Renée. "Typhoid Fever InAthens County, OhioFrom 1867-1903:Mortality, Social NetworksAnd Cultural Status." Ohio University Art and Sciences Honors Theses / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ouashonors1430344483.
Повний текст джерелаHart, Peter. "Comparison of the immune response to typhoid fever and invasive nontyphoidal Salmonella disease." Thesis, University of Birmingham, 2015. http://etheses.bham.ac.uk//id/eprint/6023/.
Повний текст джерелаЛиповська, Вікторія Вікторівна, Виктория Викторовна Липовская, Viktoriia Viktorivna Lypovska та А. В. Галушко. "О возможности ликвидации брюшного тифа в Украине". Thesis, Сумский государственный университет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/32131.
Повний текст джерелаTsoi, Hoi-wah. "Effect of antibiotics on the immune response induced by live-attenuated Salmonella typhi /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2121315X.
Повний текст джерелаGonzalez-Escobedo, Geoffrey. "Salmonella spp. Interactions with the Gallbladder during Chronic Carriage." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1374146434.
Повний текст джерелаJenkins, Aaron. "A nested environmental approach to typhoid epidemiology in Central Division, Fiji." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2017. https://ro.ecu.edu.au/theses/1992.
Повний текст джерелаGarcia, Lopez Claudia Monica. "From medical geography to germ theory in Colombia, 1860-1900." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/4303.
Повний текст джерелаTsoi, Hoi-wah, and 蔡海華. "Effect of antibiotics on the immune response induced by live-attenuated Salmonella typhi." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31223540.
Повний текст джерела李星凡. "脾胃湿热证治的文献研究". HKBU Institutional Repository, 2008. http://repository.hkbu.edu.hk/etd_ra/967.
Повний текст джерелаWatson, C. H. "Seroepidemiological investigations of Salmonella enterica serovar Typhi infection and the potential role of vaccination in the control of typhoid fever in Fiji." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2018. http://researchonline.lshtm.ac.uk/4649219/.
Повний текст джерелаDimech, Cristiane Penaforte do Nascimento. "Avaliação do sistema de vigilância epidemiológica da Febre Tifóide no Brasil." Programa de pós-graduação em saúde coletiva, 2005. http://www.repositorio.ufba.br/ri/handle/ri/10329.
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A febre tifóide (FT) é uma doença de distribuição universal, associada às precárias condições higiênico-sanitárias. Nas regiões Norte e Nordeste do Brasil a doença é endêmica, com ocorrência freqüente de surtos. A vigilância epidemiológica (VE) da FT representa importante ferramenta para detecção oportuna de surtos visando impedir ou dificultar a sua propagação. Objetivos: Avaliar o sistema de vigilância da febre tifóide no Brasil, entre os anos de 2001 a 2003. Métodos: Um estudo descritivo foi realizado baseado nas Diretrizes dos Centers for Disease Control and Prevention (CDC, EUA) publicado em 1988. A fonte de dados incluiu informações do Sistema de Informação de Agravos de Notificação (Sinan) e o Sistema de Informação sobre Mortalidade (SIM). Os atributos avaliados foram qualitativos (simplicidade, flexibilidade, aceitabilidade) e quantitativos (sensibilidade, valor preditivo positivo- VPP, representatividade, oportunidade). Resultados: O sistema de vigilância é complexo envolvendo vários níveis de gestão para transferência dos dados, com mais de 30 mil unidades notificadoras vários formulários para notificação de caso ou surto. A ficha individual de investigação apresenta mais de 70 campos. A aceitabilidade é baixa pela ausência de preenchimento de campos importantes para a VE: 54% das variáveis estavam incompletas em mais de 50% dos dados. A flexibilidade do sistema não foi possível avaliar pela ausência de informações. A sensibilidade do Sinan para óbitos foi baixa (19%) e ambos os sistemas detectaram apenas 54% dos óbitos estimados (N=52). O VPP dos casos encerrados pelo critério laboratorial foi abaixo: 29% em 2001, 44% em 2002 e 41% em 2003. O sistema foi oportuno, com uma mediana de 07 dias para a notificação após o início dos sintomas, < de 01 dia para a investigação e 25 dias para o encerramento dos casos. O sistema é representativo pela alta cobertura do Sinan e SIM no país, no entanto, há limitações quanto ao subregistro de casos. Conclusão: Apesar do baixo desempenho, o sistema de vigilância da FT é útil para análise das informações de morbidade e mortalidade e o efeito das medidas de controle e prevenção. Porém, o sistema precisa melhorar a sensibilidade e aceitabilidade para alcançar seus objetivos mais eficientemente. Desta forma, recomendamos capacitação dos profissionais de saúde na detecção, notificação e investigação de FT.
Salvador
李捍東. "《傷寒論》脾胃學說之探討". HKBU Institutional Repository, 2008. http://repository.hkbu.edu.hk/etd_ra/968.
Повний текст джерелаFusari, M. M. "SYNTHESIS OF FRAGMENTS OF SALMONELLA TYPHI CAPSULAR POLYSACCHARIDE AND THEIR ZWITTERIONIC ANALOGUES." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/243479.
Повний текст джерелаKaur, Avinash. "Nucleic acid based method for the rapid diagnosis of salmonella typhi and paratyphi a." Thesis, 2018. http://localhost:8080/xmlui/handle/12345678/7694.
Повний текст джерелаNwakuwa, Esther Promise. "Time series analysis on rate of malaria and typhoid fever: case study Nigeria (2003-2017)." Master's thesis, 2020. http://hdl.handle.net/10362/109203.
Повний текст джерелаMalaria and typhoid fever are major causes of death in Sub-Saharan African countries. Due to the high risk of these two diseases in Sub-Saharan African countries and Nigeria in particular, this dissertation investigate the incidence of malaria and typhoid fever in Nigeria from January 2003 to December 2017 with the aim of identifying an appropriate statistical model that can be used to describe the trend of malaria and typhoid fever and make future projections of the two diseases in Nigeria which will serve as guide to policy makers in reducing the incidence of the two diseases. Several statistical methods were used in this research work. The Least Square Estimation was used to estimate the trend of both malaria and typhoid fever and the trend line equation obtained shows a gradual downward trend movement for both diseases. Arima modeling was used to describe the general behavior and pattern of occurrence of both diseases over the period under study and forecasts of future occurrence were made. SARIMA model was identified as the appropriate model for both malaria and typhoid fever. This result shows that the incidence of both diseases is influenced by seasonal factor. High occurrence of both diseases is expected around May to August according to the forecasts obtained in this study. The Chi-square test of association was used to ascertain if any form of association exists between gender and the diseases and the result obtained shows that there is no significant association between gender and the diseases. Correlation analysis conducted shows that there is a strong relationship between the two diseases.
Highet, Megan J. "Gold fever: death and disease during the Klondike gold rush, 1898-1904." 2008. http://hdl.handle.net/1993/3076.
Повний текст джерелаOctober 2008
Chatterjee, Ritika. "Deciphering the mechanisms employed by Salmonella to mediate modulation of host endo-lysosomal machinery." Thesis, 2022. https://etd.iisc.ac.in/handle/2005/5955.
Повний текст джерелаCSIR
Charles, Marthe K. "Caractérisation du produit du gène sty4221, unique à Salmonella enterica sérovar Typhi." Thèse, 2008. http://hdl.handle.net/1866/2657.
Повний текст джерелаSalmonella enterica serovar Typhi (Typhi) is a human restricted pathogen causing typhoid fever, a systemic infection. Annually, at least 16 million new cases with 600, 000 associated deaths are reported. It has been demonstrated that Salmonella has to survive in the macrophages of its host, in order to produce a systemic disease. This ability to cause a disseminated infection in human is unique to Typhi. Our laboratory had isolated 36 genes that were unique to Typhi (absent from Typhimurium’s genome), and that were expressed during human macrophages infection. One of these genes, sty4221, a putative aminotransferase, was of high interest since it shares sequence similarities with a known hemolysin (Hly), which also possesses an aminotransferase activity. That hemolysin is produced by Treponema denticola, it catabolizes cysteine and produces H2S, a toxic metabolite for the host. Our hypothesis is that host specificity and the ability to cause a systemic infection might be explained by the expression of genes that are not found in other salmonellas. The goal of this study was to characterize the gene sty4221, in terms of hemolytic and cytotoxic activity and to determine its role in virulence. The sty4221gene has been cloned in a vector under an arabinose inducible promoter and transformed in a strain of E. coli. The hemolytic activity has been investigated on blood-agar medium. To evaluate the cytotoxicity of the STY4221 protein on human cultured cells, direct observation by photonic microscopy was done. The cytotoxicity activity on human cultured cells has been quantitatively measured with a lactate dehydrogenase release assay. Moreover, the sty4221 gene has been deleted in order to study its implication in the infection and the survival within human macrophages and for adhesion/invasion on epithelial. Protein purification was also attempted. We now know that protein STY4221 has a hemolytic activity that is enhanced by cysteine. Also, we proved that the expression of sty4221 has a cytotoxic effect on THP-I macrophages, but not on epithelial HeLa cells. Meanwhile, sty4221 does not seem to be important during adhesion, invasion, infection nor survival. The characterization of protein STY4221 might extend the list of known exotoxin of Typhi.
von, Grumbkow Philipp. "Das Leben in der napoleonischen Armee - interdisziplinäre Untersuchung eines Massengrabs aus Kassel, Hessen." Doctoral thesis, 2013. http://hdl.handle.net/11858/00-1735-0000-0001-BC00-A.
Повний текст джерелаBéland, Maxime. "Implication des gènes de Salmonella enterica sérovar Typhi dans les différentes étapes d'infection." Thèse, 2008. http://hdl.handle.net/1866/7636.
Повний текст джерелаSabbagh, Sébastien. "Identification et caractérisation de gènes chez Salmonella enterica sérovar Typhi impliqués dans l’interaction avec les macrophages humains." Thèse, 2013. http://hdl.handle.net/1866/10868.
Повний текст джерелаThe bacterial genus Salmonella holds over 2500 serovars, but few are responsible for human pathologies. Salmonella enterica serovar Typhi (S. Typhi) is recognized across the globe for its medical importance. S. Typhi causes typhoid fever in humans, a lethal infectious disease characterized by systemic dissemination of the bacteria to organs of the reticulo-endothelial system. Typhoid fever represents a burden for public health, notably in developing countries where sanitary conditions are obsolete. The situation is further complicated by the appearance of strains resistant to antibiotics. Moreover, both of the licensed vaccines are of moderate efficiency, present certain technical constraints and are not appropriate for young children and newborns. The systemic phase of infection by Salmonella relies on its survival within macrophages of the immune system. In this intracellular compartment, the bacterium modulates antimicrobial defenses thanks to multiple virulence factors encoded within its genome. Molecular mechanisms taking place are complex and finely regulated. Despite scientific advances made previously, many misunderstandings persist concerning the adaptation of this pathogen within host macrophages. To better conceive the genetic determinants of S. Typhi involved in interaction with these cells, a negative selection strategy was applied to systematically verify the direct effect of genes during infection. Firstly, a library of transposon insertion mutants in S. Typhi was created for infection of cultured human macrophages. After 24 hours of infection, the presence of mutants was evaluated simultaneously by analysis on Salmonella microarrays. In total, 130 genes were selected for their potential contribution within infected macrophages. These genes included bacterial envelope components, fimbrial elements, portions of the flagellum, regulators, pathogenesis factors, and many proteins of unknown function. Secondly, this collection of genes led to the creation of 28 defined deletion mutants in S. Typhi. The ability of entry and intracellular replication of these mutants within human macrophages were characterized. To start, macrophages were coinfected with mutants in the presence of the wild-type strain, in order to verify the competitiveness of each of them against the latter. Then, mutants were inoculated individually into macrophages and their infectiveness was measured in comparison with the wild-type strain. In summary, 26 mutants presented defects when in competition, whereas 14 mutants were shown defective when tested alone. Furthermore, 12 mutants exposed a deficiency during mixed and individual infection experiments, including mutants acrA, exbDB, flhCD, fliC, gppA, mlc, pgtE, typA, waaQGP, STY1867-68, STY2346, and SPI-4. In particular, 35 new defective phenotypes of Salmonella entry or intracellular survival were revealed in this study. Data generated here provides significant novel insight for elucidating how S. Typhi manipulates its intracellular niche, leading to systemic infection. Genes described represent potential targets for attenuating the bacteria in the human host and could contribute to the development of better vaccine strains to immunize against typhoid fever.