Добірка наукової літератури з теми "Tri-delivery"
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Статті в журналах з теми "Tri-delivery"
Zhao, Yinan, Shubiao Zhang, Yuan Zhang, Shaohui Cui, Huiying Chen, Defu Zhi, Yuhong Zhen, Shufen Zhang, and Leaf Huang. "Tri-peptide cationic lipids for gene delivery." Journal of Materials Chemistry B 3, no. 1 (2015): 119–26. http://dx.doi.org/10.1039/c4tb01312c.
Повний текст джерелаNorris, Debra A., Joy P. Burke, and Anna L. Speer. "Tri-level service delivery: An alternative consultation model." School Psychology Quarterly 5, no. 2 (1990): 89–110. http://dx.doi.org/10.1037/h0090605.
Повний текст джерелаMondal, Pravakar, Hemant H. Alur, and Thomas P. Johnston. "Evaluation of TRI-726 as a drug delivery matrix." Drug Development and Industrial Pharmacy 37, no. 8 (March 21, 2011): 995–1001. http://dx.doi.org/10.3109/03639045.2011.555913.
Повний текст джерелаRao, Shasha, Yunmei Song, Frank Peddie, and Allan M. Evans. "A novel tri-layered buccal mucoadhesive patch for drug delivery: assessment of nicotine delivery." Journal of Pharmacy and Pharmacology 63, no. 6 (May 3, 2011): 794–99. http://dx.doi.org/10.1111/j.2042-7158.2011.01283.x.
Повний текст джерелаZaw Thin, May, Helen Allan, Robin Bofinger, Tomas D. Kostelec, Simon Guillaume, John J. Connell, P. Stephen Patrick, et al. "Multi-modal imaging probe for assessing the efficiency of stem cell delivery to orthotopic breast tumours." Nanoscale 12, no. 31 (2020): 16570–85. http://dx.doi.org/10.1039/d0nr03237a.
Повний текст джерелаZhao, Y. N., Y. Z. Piao, C. M. Zhang, Y. M. Jiang, A. Liu, S. H. Cui, D. F. Zhi, Y. H. Zhen, and S. B. Zhang. "Replacement of quaternary ammonium headgroups by tri-ornithine in cationic lipids for the improvement of gene delivery in vitro and in vivo." J. Mater. Chem. B 5, no. 39 (2017): 7963–73. http://dx.doi.org/10.1039/c7tb01915g.
Повний текст джерелаGamache, Raymond F., Kirstin A. Zettlitz, Wen-Ting K. Tsai, Jeffrey Collins, Anna M. Wu, and Jennifer M. Murphy. "Tri-functional platform for construction of modular antibody fragments for in vivo18F-PET or NIRF molecular imaging." Chemical Science 11, no. 7 (2020): 1832–38. http://dx.doi.org/10.1039/c9sc05007h.
Повний текст джерелаGajendiran, M., and S. Balasubramanian. "Biodegradable Amphiphilic Tri-Block Copolymeric Nanoparticles for Controlled MTB Drug Delivery." Advanced Materials Research 584 (October 2012): 460–64. http://dx.doi.org/10.4028/www.scientific.net/amr.584.460.
Повний текст джерелаNewby, Gemma E., Erik B. Watkins, Daniel Hermida Merino, Paul A. Staniec, and Oier Bikondoa. "In situ Rheo-GISANS of triblock copolymers: gelation and shear effects on quasi-crystalline structures at interfaces." RSC Advances 5, no. 126 (2015): 104164–71. http://dx.doi.org/10.1039/c5ra20215a.
Повний текст джерелаMegawari, Megawari, Djoni Djoni, and Culita Culita. "Analisis dan Perancangan Sistem Pembelian dan Pengolahan TBS pada PT. Tri Bahtera Srikandi." remik 6, no. 1 (November 30, 2021): 70–81. http://dx.doi.org/10.33395/remik.v6i1.11223.
Повний текст джерелаДисертації з теми "Tri-delivery"
Zheng, Xian-Ling, and 丁先玲. "Risk factors of preterm delivery of tri-service general hospital a case-control study." Thesis, 1987. http://ndltd.ncl.edu.tw/handle/91312089189074654128.
Повний текст джерелаDING, XIAN-LING, and 丁先玲. "Risk factors of preterm delivery of tri-service general hospital a case-control study." Thesis, 1987. http://ndltd.ncl.edu.tw/handle/13015420107419128591.
Повний текст джерелаChoonara, Bibi Fatima. "A Tri-Functionalized Oral Core-Melt Tablet (OCMT) for enhanced delivery of gastro-sensitive proteins and synthetic peptides." Thesis, 2017. https://hdl.handle.net/10539/24911.
Повний текст джерелаThe global pharmaceutical biotechnology industry is continually growing and increased amounts of protein and peptide-based therapeutics are entering into the market. Conventionally, these therapeutic proteins and peptides are administered intravenously, subcutaneously or intramuscularly as oral routes of administration may result in their degradation in the gastrointestinal tract (O’ Connor, 2009). The parenteral route limits patient acceptability and convenience. Oral dosage forms, particularly tablets, are considered one of the most common and widely used routes of drug administration and accounts for approximately 50% of all dosage forms on the market (Oh et al., 2012). Thus, the development of oral technologies for therapeutic proteins and peptides remain a dynamic research field despite its many challenges. Successful oral delivery of proteins and peptides require the accomplishment of three key tasks: protection of the macromolecules from degradation in the gastrointestinal tract (GIT), permeation through the intestinal barrier and the absorption of molecules into the systemic circulation. Currently, no clinically useful oral formulations have been approved but several attempts have been made to overcome the challenges of low oral bioavailability resulting from poor absorption, poor permeation and enzymatic degradation of the proteins and peptides in the GIT. Present strategies attempt to provide structural protection of the proteins and peptides and improved absorption through the use of enzyme inhibitors, absorption enhancers, novel polymeric delivery systems and chemical modification. However, each of these technologies possesses limitations that preclude the successful oral delivery of proteins and peptides. The design and development of the novel Tri-functionalized OCMT attempts to breakthrough this market by triple targeting the major challenges governing successful oral delivery of proteins and peptides. Essentially, the Tri-functionalized OCMT is made up of three distinct functional components; the core-eutectic region, the outer polymer shell and the ‘smart’ polymeric sheet. Triple targeting was achieved by incorporating the bioactive into a core-melt archetype within the tablet and facilitating the process of in situ crosslinking which significantly affects the way the bioactive is protected within the compressed tablet matrix as well providing desirable bioactive release kinetics. In addition, the incorporation of a co-inhibitory ‘smart’ polymeric sheet provided added protection and enabled an improved absorption by virtue of its intrinsic properties and co-inhibition of the major determinants, CYP3A4 and Pgp, of poor absorption and low oral bioavailability. Lastly, targeting of enzymatic degradation was achieved by incorporation of a pH modifier that functions to transiently lower the micro-environmental pH and reduce the optimal environment for enzyme activity. The combination of the distinct formulatory components contained within the Tri-functionalized OCMT was extensively evaluated through in-depth in vitro physicochemical and physicomechanical characterization, ex vivo analyses and in vivo performance. In vitro and ex vivo characterization enabled the optimization of design variables and promoted the achievement of desirable functionalities for the attainment of optimum in vivo performance. In vivo analyses of the Tri-functionalized OCMT in the Large White pig model revealed an enhanced oral bioavailability of the incorporated peptides, octreotide and exenatide, following oral administration, as compared to their conventionally administered subcutaneous counterparts. In addition, pharmacokinetic analysis of the Tri-functionalized OCMT confirmed the maintenance of sustained, therapeutic levels of both octreotide and exenatide over the 24 hour period, supporting a convenient once-daily dosing. The rate at which protein and peptide-based therapeutics are developing is astounding, and this consequently increases the demand and focus towards achieving a simpler and more effective oral delivery of therapeutic proteins and peptides. The Tri-functionalized OCMT has successfully demonstrated its feasibility in enhancing the oral delivery of therapeutic proteins and peptides up to a preclinical stage. It may potentially serve as a viable alternative to the conventional parenteral route of administration for the treatment of various disease conditions by incorporating a multitude of proteins and peptides into its versatile design. The advancement of the Tri-functionalized OCMT to the clinical stage and beyond may ultimately improve patient outcomes and change the face of therapeutic protein and peptide delivery globally.
LG2018
Yun, Seonho. "Intracellular Microenvironment Triggered Co-delivery of Anticancer Drugs and Genes." Thesis, 2019. http://hdl.handle.net/2440/120605.
Повний текст джерелаThesis (Ph.D.) -- University of Adelaide, School of Chemical Engineering and Advanced Materials, 2019
Книги з теми "Tri-delivery"
Schneider, Dona. Public health and public health services: The Connecticut-New Jersey-New York, Tri-State Region. New Brunswick, N.J: Center for Urban Policy Research, 1992.
Знайти повний текст джерелаЧастини книг з теми "Tri-delivery"
Zhai, Congcong, Junni Zou, and Yunfei Zhang. "Video Content Caching and Delivery for Tri-Party Joint Profit Optimization." In Lecture Notes in Computer Science, 239–51. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-71589-6_22.
Повний текст джерелаNasongkla, N., P. Akarajiratun, and S. Hongeng. "Development of Tri-component Copolymer Rods as Implantable Drug Delivery Systems for Liver Cancer Therapy." In IFMBE Proceedings, 317–20. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03887-7_92.
Повний текст джерелаManisekaran, Ravichandran. "Designing a Nanocargo with Fe3O4@Au: A Tri-pronged Mechanism for MR Imaging, Synaphic Drug-Delivery, and Apoptosis Induction in Cancer Cells." In Springer Theses, 91–113. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-67609-8_4.
Повний текст джерелаТези доповідей конференцій з теми "Tri-delivery"
Kwon, Ohyeon, and Jong-Un Won. "Measurement of the Delivery Environment Using Demo Parcel with Tri-axial Accelerometer." In 2019 34th International Technical Conference on Circuits/Systems, Computers and Communications (ITC-CSCC). IEEE, 2019. http://dx.doi.org/10.1109/itc-cscc.2019.8793436.
Повний текст джерелаMair, Hugh, Gordon Lin, Achuta Thippana, Kent Li, Manzur Rahman, Wuan Kuo, David Yen, et al. "3.4 A 10nm FinFET 2.8GHz tri-gear deca-core CPU complex with optimized power-delivery network for mobile SoC performance." In 2017 IEEE International Solid-State Circuits Conference (ISSCC). IEEE, 2017. http://dx.doi.org/10.1109/isscc.2017.7870258.
Повний текст джерелаKelsey, Matthew, Thomas Fanchin, Steffen Van Der Veen, Espen Dahl, and Kristina Harila Skjold. "Multilateral Technology Enables Record Reservoir Contact in North Sea Subsea Well." In SPE Annual Technical Conference and Exhibition. SPE, 2022. http://dx.doi.org/10.2118/210399-ms.
Повний текст джерелаKrishnakumar, D., and K. S. Jaganathan. "Development of nasal HPV vaccine formulations." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685403.
Повний текст джерелаKuyken, Chris Wilhelm, Mohamed Elsaied Elkasrawy, Ali Mubarak Saeed Al Breiki, Yahia Abdelfattah Mahmoud Elgendy, and Ahmed Gamal Abdelaal. "High Performance Drilling Onshore Abu Dhabi." In SPE/IADC Middle East Drilling Technology Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/202142-ms.
Повний текст джерелаKelsey, Matthew, Thomas Fanchin, Steffen Van Der Veen, and Marie Houge Nesheim. "Multilateral Re-Entry Technology Compounding Benefits and Extending Production Life Past Two Decades." In Offshore Technology Conference. OTC, 2022. http://dx.doi.org/10.4043/31855-ms.
Повний текст джерелаKelsey, Matthew, Thomas Fanchin, Steffen Van Der Veen, and Marie Houge Nesheim. "Multilateral Re-Entry Technology Compounding Benefits and Extending Production Life Past Two Decades." In Offshore Technology Conference. OTC, 2022. http://dx.doi.org/10.4043/31855-ms.
Повний текст джерелаЗвіти організацій з теми "Tri-delivery"
Gaffney, Anne, Richard Boardman, Shannon Bragg-Sitton, Gary Groenewold, Daniel Ginosar, Jeff Aguiar, Gabriel Ilevbare, et al. Materials Challenges and Opportunities for Energy Generation, Conversion, Delivery, and Storage (Applied Energy Tri-Laboratory Consortium Workshop Report). Office of Scientific and Technical Information (OSTI), June 2021. http://dx.doi.org/10.2172/1785315.
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