Дисертації з теми "Total synthesis of GA18"
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Watson, Christine Anne Louise. "Total synthesis of bistheonellic acid B/ total synthesis of scytophycin C." Thesis, University of Cambridge, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627216.
Повний текст джерелаChan, Bryan Ka Ip. "Total synthesis of streptonigrone." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/31581.
Повний текст джерелаScience, Faculty of
Chemistry, Department of
Graduate
Shelton, Ruth E. "Total synthesis of peduncularine." Thesis, University of Oxford, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526451.
Повний текст джерелаSparling, Brian Andrew. "Total Synthesis of Hyperforin." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:11098.
Повний текст джерелаChemistry and Chemical Biology
Baldwin, Ian Robert. "Total synthesis of acetoxyodontoschismenol." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284653.
Повний текст джерелаChen, Cheng Yi. "Total synthesis of (+)-stenine /." The Ohio State University, 1990. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487684245465948.
Повний текст джерелаLi, Fang. "Total Synthesis of (-)-Acutumine." BYU ScholarsArchive, 2009. https://scholarsarchive.byu.edu/etd/2193.
Повний текст джерелаShamim, Khalida. "I. Total synthesis of stemonine. II. Studies towards the total synthesis of kendomycin." [Bloomington, Ind.] : Indiana University, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3243781.
Повний текст джерелаTitle from PDF t.p. (viewed Nov. 18, 2008). Source: Dissertation Abstracts International, Volume: 67-12, Section: B, page: 7099. Adviser: David R. Williams.
Liu, Qingsong. "Large scale total synthesis of apoptolidinone and progress towards the total synthesis of ammocidin." [College Station, Tex. : Texas A&M University, 2006. http://hdl.handle.net/1969.1/ETD-TAMU-1054.
Повний текст джерелаZhang, Yan Crimmins Michael T. "Total synthesis of (-)-mucocin and studies toward the asymmetric total synthesis of brianthein A." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1414.
Повний текст джерелаTitle from electronic title page (viewed Apr. 25, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry." Discipline: Chemistry; Department/School: Chemistry.
Hassan, Haitham. "Total synthesis of eucophylline : a free-radical approach towards total synthesis of cytotoxic leucophyllidine." Thesis, Bordeaux, 2016. http://www.theses.fr/2016BORD0153/document.
Повний текст джерелаThe thesis describes the first total synthesis of Eucophylline, the south fragment of the Leucophyllidine alkaloid recently isolated from Leuconotis griffithiiand L. eugenifolius. The 10-step synthesis encompasses a new straight forward method to access to the azabicyclo[3.3.1]nonane skeleton through a free-radical three-component olefinic carbo-oximation process. During these studies, we also isolated enamines exhibiting unusual stabilities resulting from their strained bicyclicconformation. The synthesis of the Eburnane part, the north fragment of Leucophyllidine, was developed relying on a new free-radical three-component Carbo-Cyanation reaction. This new reaction showed high tolerance toward different functional groups and provided an efficient mean to install the nitrile group in complex structures and to introduce quaternary centers. The biomimetic coupling between the Eburnane and Eucophylline fragments was finally studied using structurally similar models. Preliminary results of this model study showed that absence of a gemdimethyleffect in the Eburnane model probably prevents the formation of the cyclicimine, key intermediate for the desired coupling
Ballette, Roberto. "Total synthesis of (+)-Madangamine D." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/145559.
Повний текст джерелаLas esponjas del orden Haplosclerida representan una importante fuente de alcaloides estructuralmente diversos pero biogenéticamente relacionados, siendo las madangaminas uno de los menos estudiados desde el punto de vista sintético. En 1994 fue aislada el primer alcaloide de este grupo, la Madangamina A de la esponja marina Xestospongia ingens1 y unos años más tarde se aislaron cuatro nuevos alcaloides, las madangaminas BE.2 Estructuralmente, las madangamines son alcaloides pentacíclicos y se caracterizan por presentar un núcleo diazatricíclico (anillos ABC) y dos puentes de carbonados. El anillo macrocíclico D es diferente en cada madangamina en tamaño, así como en el grado y la posición de insaturación, mientras que el anillo E es idéntico en todas ellas. En la presente Tesis Doctoral presentamos la síntesis enantioselectiva de ()-madangamine D,3 que ofrece por primera vez una muestra pura de este producto natural y constituye la primera síntesis total de un alcaloide de la grupo de las madangamines. Usando de una lactama bicíclica derivada del fenilglicinol como el scafold enantiomérico de partida, nuestro enfoque consiste en la construcción inicial del núcleo diazatricíclico ABC y la posterior construcción de los anillos macrocíclicos D y E. La lactama de partida 2 es fácilmente accesible por ciclocondensación de oxoester 1 con el (R)-fenilglicinol, en un proceso en donde se instala el primer estereocentro. El intermedio diazatríclico se prepara a partir de una lactama insaturada derivada de 2. En este proceso son claves una reacción de adición conjugada estereoselectiva, el cierre del anillo carbocíclico mediante metátesis, una alquilación estereoselectiva y finalmente cierre del anillo A por aminohidroxilación. La anulación de los anillos macrocíclicos se lleva a cabo mediante una reacción de cierre del anillo por metátesis (anillo D) y una olefinación de Wittig seguida de macrolactamización (anillo E). Los datos de RMN de 1H y 13C de nuestra madangamina sintética fueron coincidentes con los reportados para el producto natural. La madangamina D sintética muestra citotoxicidad in vitro contra las líneas celulares de cáncer HT29 de colon humano y PSN1 páncreas.
Kleinbeck, Florian Karl. "Total synthesis of bafilomycin A₁ /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17777.
Повний текст джерелаBosch, Caroline. "Total Synthesis of Phlegmarine Alkaloids." Doctoral thesis, Universitat de Barcelona, 2016. http://hdl.handle.net/10803/399380.
Повний текст джерелаChiba, Hiroaki. "Total Synthesis of Tetrahydroisoquinoline Alkaloids." 京都大学 (Kyoto University), 2013. http://hdl.handle.net/2433/174544.
Повний текст джерелаXu, Sanjia. "Formal total synthesis of (±)-tetrodotoxin." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/59489.
Повний текст джерелаScience, Faculty of
Chemistry, Department of
Graduate
Lefranc, David. "Total synthesis of micrococcin P1." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/3626.
Повний текст джерелаAulakh, Virender Singh. "Total synthesis of thiocillin I." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/29493.
Повний текст джерелаScutt, James Nicholas. "Total synthesis of (+)-belactosin A." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419852.
Повний текст джерелаBebbington, David. "Total synthesis of hypoglycin A." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306112.
Повний текст джерелаHayes, Stewart. "The total synthesis of vigulariol." Thesis, University of Nottingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495554.
Повний текст джерелаAnderson, Regan J. "Total synthesis of variolin B." Thesis, University of Canterbury. Chemistry, 2002. http://hdl.handle.net/10092/6061.
Повний текст джерелаBrooke, Darby Gerard. "Total synthesis of hydroxystrobilurin A." Thesis, University of Canterbury. Chemistry, 2002. http://hdl.handle.net/10092/6541.
Повний текст джерелаBeiger, Jason James. "Total Synthesis of Aflastatin A." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:11040.
Повний текст джерелаChemistry and Chemical Biology
George, Ian R. "The total synthesis of lodopyridone." Thesis, University of Nottingham, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.663246.
Повний текст джерелаLineswala, Jayana P. "Total synthesis of lavendamycin amides." Virtual Press, 1996. http://liblink.bsu.edu/uhtbin/catkey/1036197.
Повний текст джерелаDepartment of Chemistry
Stocksdale, Mark G. "Total synthesis of lavendamycin analogs." Virtual Press, 1992. http://liblink.bsu.edu/uhtbin/catkey/834647.
Повний текст джерелаDepartment of Chemistry
Olang, Fatemeh. "Total synthesis of lavendamycin analogs." Virtual Press, 1995. http://liblink.bsu.edu/uhtbin/catkey/958797.
Повний текст джерелаDepartment of Chemistry
Stonehouse, Jeffrey Paul. "Total synthesis of (+)-rhizoxin D." Thesis, University of Nottingham, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395458.
Повний текст джерелаMartin, Bruce John. "A total synthesis of myxothiazol." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283643.
Повний текст джерелаSherlock, Alexandra. "A total synthesis of (+)-lactacystin." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431860.
Повний текст джерелаOehlrich, Daniel. "Total synthesis of luminacin D." Thesis, University of Warwick, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412862.
Повний текст джерелаTometzki, G. B. "d1-Progesterone : A total synthesis." Thesis, University of Manchester, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374578.
Повний текст джерелаKay, Claire-Louise. "The total synthesis of membrarollin." Thesis, University of Southampton, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438693.
Повний текст джерелаRussell, M. A. "Total synthesis of the nikkomycins." Thesis, Imperial College London, 1985. http://hdl.handle.net/10044/1/37839.
Повний текст джерелаBroughton, Howard Barff. "A total synthesis of showdomycin." Thesis, Imperial College London, 1985. http://hdl.handle.net/10044/1/37646.
Повний текст джерелаSaint-Dizier, François. "The total synthesis of concavine." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/7135/.
Повний текст джерелаStraub, Julie Ann. "The total synthesis of carbohydrates." Thesis, Massachusetts Institute of Technology, 1987. http://hdl.handle.net/1721.1/14622.
Повний текст джерелаButtler, Thomas. "A total synthesis of (+/-)-sparteine." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616083.
Повний текст джерелаFlorence, Gordon John. "The total synthesis of (+)-discodermolide." Thesis, University of Cambridge, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621038.
Повний текст джерелаBotha, Marc Edgar. "The total synthesis of aristolindiquinone." Master's thesis, University of Cape Town, 1986. http://hdl.handle.net/11427/22134.
Повний текст джерелаAristolindiquinone (1), a novel natural compound possibly: possessing anti-fertility activity, was synthesized via two independent routes. First, a Stobbe reaction unambiguously gave the naphthalene nucleus with the required substitution pattern (3,8-dioxygenated-2,5-dimethyl naphthalene), starting from 2-hydroxy-5-methylbenzaldehyde (31). Second, a general synthesis, of substituted C-5 oxygenated- 1,4-naphthoquinones is applied to the synthesis of (1). The critical step in the synthesis is the reaction of the novel Diels-Alder partners, dienophile (90), synthesized from 2,6-dihydroxytoluene (56), and diene (109).
Hong, Won-Pyo. "Total synthesis of (±)-lythrancepine-II /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu148726191911152.
Повний текст джерелаLai, Chin-Shan. "Total synthesis of axane sesquiterpenoids /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487758680163008.
Повний текст джерелаKennedy, Robert M. "A total synthesis of aphidicolin." Diss., Virginia Polytechnic Institute and State University, 1985. http://hdl.handle.net/10919/54307.
Повний текст джерелаPh. D.
Liu, Yong-Peng. "Total Synthesis of Microsclerodermin D." Thesis, université Paris-Saclay, 2020. http://www.theses.fr/2020UPASF024.
Повний текст джерелаMicrosclerodermin D is a macrocyclic peptide of marine origin which contains six amino acids, of which two are commercially available: glycine (Gly) and sarcosine (Sar). The four other amino acids: (R)-γ-amino-β-hydroxybutyric acid (GABOB), D-6-chlorotryptophan (6-Cl-Trp), a polyhydroxylated β-amino acid (APTO) and 3-amino-4-hydroxypyrrolidinoacetic acid (PyrrAA) will be accessible by new synthetic routes. Our goal is to develop a modular synthetic route to microsclerodermin D that could be applicable for the preparation of other microsclerodermin family members and analogues thereof. We are also looking forward to make some investigations on their biological activities or potential as anticancer drug
Morris, Joanne Charleen. "The total synthesis of chamuvarinin." Thesis, University of St Andrews, 2013. http://hdl.handle.net/10023/4114.
Повний текст джерелаFouche, Marianne. "Total synthesis of cruentaren A." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/14610.
Повний текст джерелаSalehi-Rad, Ramin. "Total synthesis of auripyrone A." Diss., Restricted to subscribing institutions, 2009. http://proquest.umi.com/pqdweb?did=1973896461&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.
Повний текст джерелаGoh, Simin Shermin. "Total synthesis of rubriflordilactone A." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:796adfdf-b4d5-474d-85a6-d2e19c1085db.
Повний текст джерелаWada, Hiroki. "Total synthesis of plantazolicin A." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/37595/.
Повний текст джерела