Дисертації з теми "Titanium biomedical implants"
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Hoffmann, Ilona. "MAGNESIUM-TITANIUM ALLOYS FOR BIOMEDICAL APPLICATIONS." UKnowledge, 2014. http://uknowledge.uky.edu/cme_etds/36.
Повний текст джерелаThompson, Rebecca. "Effect of locally delivered alendronic acid on bone formation around porous titanium implants." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116924.
Повний текст джерелаL'objectif de cette étude était de déterminer les effets d'une administration localedu biphosphonate acide alendronique (AA) sur la formation osseuse sur, autour età l'intérieur d'implants poreux en titanium. Des tiges cyclindriques de 9mm dediamètre et de 90mm de longueur ont été enduites avec 0.2mg ou 1.0mg de AApréalablement à leur implantation chirurgicale bilatérale dans les canaux fémorauxintramédullaires sur 10 canins expérimentaux. Douze semaines après lachirurgie, les fémurs ont été prélevés et scannés par tomodensitométrie (microCT)avant l'histologie de sections minces décalcifiées et l'analyse par microscopie àbalayage d'électrons rétrodiffusés (BSEM). Les analyses microCT ont montréque les deux doses de AA amélioraient significativement la formation osseuse périimplantautour des implants enduits comparativement aux implants contrôles ; ladose de 1.0mg de AA résultant en une augmentation 3.5 fois supérieure à celleobtenue avec la dose de 0.2mg de AA. Les analyses BSEM de la formationosseuse péri-implant ont montré une bonne corrélation avec les analyses microCTpar une comparaison directe des sections correspondantes microCT ethistologiques. Les analyses BSEM n'ont montré d'effet significatif ni de la dose0.2mg ou 1.0mg AA sur l'apposition os-implant ou sur le niveau de croissanceosseuse dans l'implant poreux enduit. Cette thèse a permis de fournir desdonnées utiles sur la dose réponse pour une administration locale de AA ainsi quesur son potentiel pour améliorer la fixation d'implants orthopédiques en accroissantla quantité osseuse qui se forme aux environs immédiats de la zone péri-implant.
Ayyala, Somayajula Dilip. "Biocompatibility of osteoblast cells on titanium implants." Cleveland State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=csu1207322725.
Повний текст джерелаEhrensberger, Mark T. "The in-vitro biological and electrochemical interactions of electrically polarized commercially pure titanium used for orthopedic and dental applications." Related electronic resource: Current Research at SU : database of SU dissertations, recent titles available, full text:, 2008. http://wwwlib.umi.com/cr/syr/main.
Повний текст джерелаSosale, Guruprasad. "Measurement and analysis of surface topography over multiple length scales: application to titanium bone implants." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18433.
Повний текст джерелаLa performance des implants osseux dépend de façon critique de l'interaction entre la surface de l'implant et le tissu osseux environment. Le but de cette thèse est de développer une méthodologie fiable pour mesurer et analyser la topographie de surfaces non périodiques à différentes échelles. Ainsi, deux techniques de mesure extrêmement utilisées, la microscopie à force atomique et l'interférométrie à lumière blanche ont été comparées et confrontées. Un programme développé sur le logiciel MATLAB a été conçu pour analyser les images obtenues par ses deux instruments et en extraire quatorze différents paramètres topographiques statistiques. Les erreurs associées à la mesure et à l'analyse d'image ont été ensuite identifiées et des recommandations ont été suggérées pour minimiser leurs effets. Cette méthodologie a été ensuite appliquée pour mesurer les topographies de deux implants en titane communément utilisés. Il apparaît que ces deux surfaces ont une moyenne quadratique similaire pour la rugosité, mais présentent néanmoins des réponses biologiques différentes. Dans cette recherche, il a été démontré que les deux surfaces présentent, en plus, plusieurs différences pour d'autres paramètres topographiques, notamment de façon significative, pour l'inclinaison des surfaces, la courbure des pics et l'aire interraciale développée. Ces différences dépendent fortement d'un facteur d'échelle, et forment la base pour d'autres études afin de développer des relations quantitatives entre la topologie de la surface et les réponses biologiques associées.
Yeung, Che-yan, and 楊芷茵. "Antibacterial properties and biocompatibility of novel peptide incorporated titanium alloy biomaterials for orthopaedic implants." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hdl.handle.net/10722/197133.
Повний текст джерелаFang, Mimi. "The role of phospholipase d in osteoblasts in response to titanium surfaces." Thesis, Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/26462.
Повний текст джерелаCommittee Chair: Boyan, Barbara; Committee Member: Eskin, Suzanne; Committee Member: Lobachev, Kirill; Committee Member: Schwartz, Zvi. Part of the SMARTech Electronic Thesis and Dissertation Collection.
Siddiqui, Mohammad S. "Vacuum Brazing of Alumina Ceramic to Titanium Using Pure Gold as Filler Metal for Biomedical Implants." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/497.
Повний текст джерелаLeung, Kit-ying. "Anti-bacteria plasma-treated metallic surface for orthopaedics use." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41633994.
Повний текст джерелаPark, Hyuen Me (Mia) Park. "Numerical and experimental analysis of stress behavior of plasma-sprayed Bioglass on titanium /." Full text open access at:, 1996. http://content.ohsu.edu/u?/etd,587.
Повний текст джерелаVan, Zyl Willem Heber. "Investigation into the production and application of porous titanium within the biomedical field." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/96097.
Повний текст джерелаENGLISH ABSTRACT: In this study, commercially pure titanium foam was produced using space holder powder metallurgy techniques. Titanium foam is attractive as a scaffolding material for bone replacement and implants in the body. The porous morphology of the foam promotes osteogenesis, while the mechanical behaviour of the foam is closer to that of bone, which has an elastic moduli range of 5 - 40 GPa. Titanium foam was manufactured from powder mixtures of commercially pure titanium (CPTi) powder mixed with 41.4 wt% ammonium bicarbonate (ABC) powder and 1.45 wt% polyethyl glycol (PEG) powder. In this study, two CPTi powders with different particle size distributions, < 75 μm (-200 mesh, designated TiAA) and < 200 μm (-100 mesh, designated TiG), were mixed with the space holder ABC powder, that had been sieved into specified particle size ranges. The size ranges of space holder material studied were: 0 - 710, 250 - 425, 425 - 560, and 560 - 710 μm. This allowed foams with different large or macropore distributions to be produced from the different mixtures. The mixtures were uniaxially compacted at 100 MPa into transverse rupture bars. The ABC and PEG was then removed by thermal debinding in air for 5 hours at 100 °C and 1 hour at 330 °C each, consecutively. The debound samples are then sintered under high (10-6 mbar) vacuum on yttria-stabilised zirconia substrates, heating at 5 °C/min to 1200 °C, with a 2 hour hold at temperature. The microstructures of the different foams were evaluated by examining the polished samples using light optical microscopy. Three point bend tests were conducted on the sintered bars in order to determine the flexural strength and flexural modulus of the different foams. The produced foams had a relative density range between 37.5 - 62.5 % and average macro pore size range between 300 - 500 μm. The foams were found to have an elastic modulus similar to that of bone, 2 - 7 GPa. Finally, the mechanical properties of the foams were compared to known open foam mechanical models and other research projects. It was found that: (i) changes in either metal or space holder powder influences the sintering behaviour of metal foams, (ii) sintered titanium foams with similar densities but different macro/micropore size distributions have different mechanical responses to stress and (iii) the Ashby-Gibson model, based on foam density alone, gives a rough estimate of mechanical properties for the titanium foams studied, but does not capture variations due to pore size distribution.
AFRIKAANSE OPSOMMING: In hierdie studie is kommersiële suiwer titaanskuim geproduseer met behulp van ruimtehouer poeier metallurgie tegnieke. Titaanskuim is aantreklik as 'n raamwerkmateriaal vir beenvervanging en -inplantings in die liggaam. Die poreuse morfologie van die skuim bevorder osteogenese, terwyl die meganiese gedrag van die skuim naby aan dié van been is, met ‘n elasticiteitsmodulus tussen 5 - 40 GPa. Titaanskuim is vervaardig van ‘n poeier mengsel van kommersiële suiwer titaan (CPTi) poeier gemeng met 41,4 gew% ammonium bikarbonaat (ABC) poeier en 1.45 gew% poli-etileenglikol (PEG) poeier. In hierdie studie is twee tipes CPTi poeiers met verskillende deeltjiegrootteverspreiding, < 75 μm (-200 stofdigtheid, TiAA genoem) en <200 μm (-100 stofdigtheid, TiG genoem), met die ruimtehouer ABC-poeier, wat in bepaalde deeltjiegroottereekse gesif is, gemeng. Die wisselende groottes van ruimtehouer wat bestudeer is, was: 0 - 710, 250 - 425, 425 - 560, 560 - 710 μm. Dit het die vervaardiging van skuim met verskillende groot of macroporeuse vanaf die verskillende mengsels toegelaat. Die mengsel is teen 100 MPa in een rigting gekompakteer. Die ABC en PEG is dan verwyder word deur termiese ontbinding in lug vir 5 uur by 100 °C en 1 uur by 330 °C elk, onderskeidelik. Die ontbinde monsters is dan onder hoë (10-6 mbar) leemte op yttrium-gestabiliseer zirconia-substraat, met verwarming teen 5 °C/min tot 1200 °C met 'n verdere 2 uur by 1200 °C, gesinterd. Die mikrostrukture van die verskillende skuim is geëvalueer deur gepoleerde monsters met behulp van ‘n ligmikroskopie te ondersoek . Driepunt draaitoetse is op die gesinterd stawe uitgevoer om die buigsterkte en buigmodulus van die verskillende skuime te bepaal. Die vervaardigde skuime se relatiewe digtheid het tussen 37,5 - 62,5 % gewissel en die gemiddelde makroporiegrootte tussen 300 - 500 μm gewissel. Die skuim het 'n elastisiteitsmodulus soortgelyk aan dié van been getoon, 2 – 7 GPa. Ten slotte is die meganiese eienskappe van die skuim met bekende oop skuim meganiese modelle en ander navorsingsprojekte vergelyk. Daar is bevind dat: (i) veranderinge in óf metaal of ruimtehouer poeier beïnvloed die sinteringgedrag van metaalskuime, (ii) gesinterd titaniumskuim met soortgelyke digthede, maar verskillende makro / mikroporeuse verdelings, toon verskillende meganiese reaksies op stres en die Ashby-Gibson model, gebaseer op die skuimdigtheid alleen, (iii) wat 'n rowwe skatting van die meganiese eienskappe vir die bestudeerde titaniumskuime gee, maar nie die variasies ingrootteverspreiding van porieë ondervang nie.
Martin, Holly Joy. "The chemical and mechanical effects of binding chitosan to implant quality titanium." Diss., Mississippi State : Mississippi State University, 2006. http://library.msstate.edu/etd/show.asp?etd=etd-09112006-150127.
Повний текст джерелаLeung, Kit-ying, and 梁潔瑩. "Anti-bacteria plasma-treated metallic surface for orthopaedics use." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41633994.
Повний текст джерелаBell, Bryan Frederick. "Mechanisms regulating osteoblast response to surface microtopography and vitamin D." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/31711.
Повний текст джерелаCommittee Chair: Barbara Boyan; Committee Member: Andres Garcia; Committee Member: Anthony Norman; Committee Member: Nael McCarty; Committee Member: Zvi Schwartz. Part of the SMARTech Electronic Thesis and Dissertation Collection.
Reyes, Catherine Diane. "Collagen- and Fibronectin-Mimetic Integrin-Specific Surfaces That Promote Osseointegration." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/11599.
Повний текст джерелаBasso, Hellem Cristine de Souza. "Avaliação da influência dosimétrica dos implantes dentários de titânio em VMAT de cabeça e pescoço." Universidade Tecnológica Federal do Paraná, 2015. http://repositorio.utfpr.edu.br/jspui/handle/1/1422.
Повний текст джерелаThe head and neck cancer is more prevalent in men, predominantly middle or elderly age, featuring a group of individuals with high probability of having done osseointegrated dental implants. Most of these implants are made of titanium and the interaction of X-ray photons with this high atomic number material and high electron density generates scattering and disturbance on radiation dose in their interfaces, generating dosimetric uncertainties in the head and neck radiotherapy treatments. The aim of this study is to assess the dosimetric impact of dental implants of titanium in head and neck VMAT. For this, irradiation of phantom was performed in the presence of a titanium dental implant for direct field and with application of CShape Easy and Head and Neck tests proposed by the TG 119, adapted to VMAT. The planning of these cases was conducted according to criteria determined by the AAPM, with Monaco 5.0 software, and the treatment is in Linear Accelerator Synergy Elekta. The measurements were performed with Semiflex ionization chamber and electrometer US PTW, radiochromic film GafChromic EBT3 scanned with the Epson Expression XL scanner and analysis with the software VeriSoft 6.0. The results of the distribution and dose profiles found in direct irradiation field show that the presence of titanium dental implant causes significant dose disturbance. Due to the presence of the material was also increased the difference between the calculated and the measured dose when compared to irradiation of the homogeneous phantom. But in the dosimetry of TG 119 cases this difference was irrelevant. The dose calculated by the software and the measure with the ionization chamber had negligible differences, as well as the consent of the gamma criterion for cases with and without the presence of dental titanium implant. The results are satisfactory and consistent with other author’s tests in homogeneous phantoms. The impact of dental titanium implant presence can be minimized through the manual delimitation of the metal object and artifact generated and by assigning the electron density values corrected them, and include them as organs with dose constraints on optimization planning. From the testing CShape Easy and Head and Neck TG 119 of the AAPM, we have verified that following the recommendations described, the planning system Monaco 5.0 is capable of performing dose calculations with high degree of accuracy for head and neck VMAT in patients with titanium dental implant.
Forsgren, Johan. "Functional Ceramics in Biomedical Applications : On the Use of Ceramics for Controlled Drug Release and Targeted Cell Stimulation." Doctoral thesis, Uppsala universitet, Nanoteknologi och funktionella material, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-132377.
Повний текст джерелаFelaktigt tryckt som Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 710
Jensen, Rebecca Leah. "Live Cell Imaging to Investigate Bone Marrow Stromal Cell Adhesion and Migration on Titanium Surfaces: A Micro-Incubator in vitro Model." Cleveland State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=csu1391128419.
Повний текст джерелаMazinani, Arash. "Development of advanced biomedical coatings via plasma electrolytic oxidation." Thesis, 2021. https://hdl.handle.net/2440/133696.
Повний текст джерелаThesis (Ph.D.) -- University of Adelaide, School of Chemical Engineering and Advanced Materials, 2021
Ricker, Zachary Hunter. "Evaluation of a segmental titanium implant for mandibular reconstruction using a critical size defect model in the dog a pilot study /." 2009. http://digital.library.okstate.edu/etd/Ricker_okstate_0664M_10251.pdf.
Повний текст джерелаCHIN, WEI-HAN, and 陳維翰. "Study the Effects of Mechanical and Biomedical Properties of Progressive Porous Tantalum Coatings on Titanium Alloy Implant by Vacuum Plasma Spraying." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/g69nj3.
Повний текст джерела南臺科技大學
機械工程系
105
This study adopts the use of selected vacuum plasma spray (VPS) as the coating process because it produces fewer oxides and has a stable crystalline nature and excellent adhesion during cladding. Titanium alloy (Ti-6Al-4V) was chosen as the substrate and Ta powder as the coating material. Spraying was carried out in three layers. The melting rate of Ta powder was controlled by applying fine, medium, and coarse powder particle diameters to the inner, middle, and outer layer respectively to form a coating that increases porosity from inside out. In addition, the substrate was preheated at 650 ° C to enhance the interface fusing effect. After the completing of Ta powder coating, it was examined by mechanical property test and biomedical property test. Experimental results exhibited that Ta powder coating has a good cohesion with Ti-6Al-4V substrate interface. The average porosity of the coating surface is about 13%, the average roughness is about Ra: 22.2 μm, the average porosity of the cross-section (about 380 μm thick) is increased from 0.6 % of the inner layer to 7.6 % of the outer layer, and the corresponding hardness and elastic modulus (E) are decreased from 240 to 167 HV0.1 and from 148.3 to 123.1GPa, respectively. It then helps reduce the stress shielding effect of the coating and reduce the risk of coats flaking. In addition, the average bonding strength of the coating to the substrate is up to 54.5±2 MPa and the failure mode is in the coating surface and the tensile bar of the glue. In biomedical property test, when the coating was immersed in the simulated body fluid (SBF) for 3 days after alkali-(1M NaOH) and heat- treatment (300 ° C), the surface was almost full of apatite, which increases according to the soaking time, and the bioactivity is significantly higher than the non- alkali- and heat- treatment term. However, when the test items were cultured in MG-63 cells, the cells had started to spread to the surroundings 3 hours later for both with alkali- and heat- treatment and without alkali-heat treatment. The longer the cultivating time is, the greater the area expands. The two test items showed excellent biocompatibility. The results of the whole study indicate that the coating formed by Ta coating on Ti-6Al-4V substrate by VPS process can obtain excellent bonding quality and biocompatibility, and the bioactivity can be improved by alkali- and heat- treatment.