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Дисертації з теми "The UCPD"

Автор: Grafiati

Опубліковано: 11 березня 2023

Оновлено: 31 липня 2025

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1

Liebig, Michaela. "Funktionsanalyse der mitochondrialen Transportproteine UCP2, UCP3, UCPx und SOUP." [S.l. : s.n.], 2004. http://archiv.ub.uni-marburg.de/diss/z2004/0138/.

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2

Kim, Dongho, and n/a. "Regulation of mouse UCP2 and UCP3 gene expression." University of Otago. Department of Biochemistry, 2006. http://adt.otago.ac.nz./public/adt-NZDU20070424.131549.

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Uncoupling protein, UCP, present in the inner mitochondrial membrane of brown adipose tissue (BAT) contributes to adaptive thermogenesis. UCP functions as a proton pore and can dissipate the proton electrochemical gradient established by the respiratory chain during fuel oxidation, and thus generates heat without producing ATP. However, the brown adipose tissue thermogenesis is not likely to be a major mechanism in controlling energy expenditure for humans because adults have only residual amounts of the tissue. Two new members of the UCP family have been identified based on their high seque

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3

Cassell, Paul Geoffrey. "Genetic susceptibility to type II diabetes and obesity : the role of UCP2, UCP3 and CAPN10 genes." Thesis, Queen Mary, University of London, 2002. http://qmro.qmul.ac.uk/xmlui/handle/123456789/28813.

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The global prevalence of type 2 diabetes (T2DM) and obesity is increasing, with obesity the most important predisposing factor contributing to the development of T2DM. Epidemiological and genetic evidence supports a major genetic component in both multifactorial and heterogeneous disorders. The identification of disease susceptibility genes in humans could greatly assist in the elucidation of underlying pathophysiological mechanisms and allow the development of more effective preventative and therapeutic strategies for these conditions. Three candidate genes, uncoupling proteins 2 and 3 (UCP2;

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4

Couplan, Elodie. "Invalidation du gène Ucp2 et surexpression du gène Ucp1 dans le muscle : études de bioénergétique mitochondriale." Paris 6, 2003. http://www.theses.fr/2003PA066073.

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5

Van, Der Merwe Pieter de Wet. "UCTD." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/96877.

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Thesis (MSc)--Stellenbosch University, 2015.<br>ENGLISH ABSTRACT: Zygophyllum orbiculatum Welwitsch ex Oliv. from Angola and Zygophyllum stapffii Schinz from Namibia were described in the late 1800’s. Recent comparisons of these two species revealed that they were morphologically very similar except that Zygophyllum orbiculatum has unifoliolate leaves and Zygophyllum stapffii has bifoliolate leaves. The similarity of these two species was investigated using nuclear ITS (Internal Transcribed Spacer, i.e. ITS1, 5.8SrDNA, ITS2) region sequence data as phylogenetic markers. Due to almost iden

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6

Schnor, Noa Pereira Prada [UNESP]. "Associação de polimorfismos dos genes da UCP2 e UCP3 com características sociodemográficas e nutricionais de mulheres em pré operatório para cirurgia bariátrica." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/100963.

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Made available in DSpace on 2014-06-11T19:31:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-06-27Bitstream added on 2014-06-13T20:01:33Z : No. of bitstreams: 1 schnor_npp_dr_arafcf.pdf: 558138 bytes, checksum: cdccd5cf2a3b51b49ef822ebbbd26df7 (MD5)<br>Sabe-se que a obesidade possui etiologia multifatorial com forte influência de componentes genéticos. Os genes das UCPs, devido à influência no dispêndio de energia, no metabolismo lipídico, na utilização de glicose, na sensibilidade à insulina, na regulação de espécies reativas de oxigênio, se apresentam associados tanto com a obesi

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7

Schnor, Noa Pereira Prada. "Associação de polimorfismos dos genes da UCP2 e UCP3 com características sociodemográficas e nutricionais de mulheres em pré operatório para cirurgia bariátrica /." Araraquara, 2013. http://hdl.handle.net/11449/100963.

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Orientador: Maria Rita Marques de Oliveira<br>Coorientação: Rozangela Verlengia<br>Banca: Thaís Borges César<br>Banca: Anderson Marliere Navarro<br>Banca: Celso Vieira de Souza Leite<br>Banca: Telma Maria Braga Costa<br>Resumo: Sabe-se que a obesidade possui etiologia multifatorial com forte influência de componentes genéticos. Os genes das UCPs, devido à influência no dispêndio de energia, no metabolismo lipídico, na utilização de glicose, na sensibilidade à insulina, na regulação de espécies reativas de oxigênio, se apresentam associados tanto com a obesidade quanto com suas comorbidades. Po

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8

Barros, Maria Esmeralda. "Monitorização e Gestão da Dor na UCPA." Master's thesis, Instituto Politécnico de Setúbal. Escola Superior de Saúde, 2015. http://hdl.handle.net/10400.26/8352.

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Relatório de Trabalho de Projeto apresentado para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Enfermagem Médico-Cirúrgica<br>No âmbito do 2º Mestrado em Enfermagem Médico-Cirúrgica da Escola Superior de Saúde – Instituto Politécnico de Setúbal, o presente relatório pretende transmitir todo o processo desenvolvido para a aquisição das Competências Comuns e Específicas do Enfermeiro Especialista em Enfermagem em Pessoa em Situação Crítica. Inserido em contexto da Unidade Curricular Enfermagem Médico-Cirúrgica II, o Estágio III, compreende a implementação do projeto de

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9

Sancerni, Tiphaine. "Rôle du transporteur mitochondrial UCP2 dans la leucémie." Thesis, Sorbonne Paris Cité, 2019. http://www.theses.fr/2019USPCC088.

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La protéine mitochondriale UCP2 est un transporteur membranaire, pouvant exporter les intermédiaires du cycle de Krebs 4 carbones. Quand cette protéine est surexprimée dans des cellules de mélanome, elle réoriente le métabolisme cellulaire depuis la glycolyse vers la phosphorylation oxydative diminuant ainsi leur tumorigénicité. UCP2 est également présente dans les cellules immunitaires, contrôlant la prolifération des lymphocytes T activés et limitant la production des espèces réactives de l'oxygène des macrophages. Au cours de ma thèse, nous avons cherché à comprendre quel était le rôle de l

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10

Adjeitey, Cyril. "Control of Uncoupling Protein-1 (UCP1) by Phosphorylation and the Metabolic Impact of Ectopic UCP1 Expression in Skeletal Muscle of Mice." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24231.

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UCP1 is a member of the mitochondrial transmembrane anion carrier protein superfamily and is required to mediate adaptive thermogenesis in brown adipose tissue (BAT). Once activated, UCP1 uncouples mitochondrial respiration from ATP synthesis, thereby wasting the protonmotive force formed across the mitochondrial inner membrane as heat. It is hypothesized that proton leaks through UCP1 could be a molecular target to combat certain forms of obesity. Although it is well established that UCP1 is regulated by allosteric mechanisms, alternative methods such as post-translational modification still

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11

Silva, Miller da Costa Lima Batista e. "Produção de lipídeos e biomassa por mucorales (Mucor subtilíssimus UCP 1262, Cunninghamella echinulata UCP 1299 e Rhizopus microsporus UCP 1304) isolados da caatinga de Pernambuco." Universidade Católica de Pernambuco, 2017. http://tede2.unicap.br:8080/handle/tede/991.

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Submitted by Biblioteca Central (biblioteca@unicap.br) on 2018-05-23T18:20:35Z No. of bitstreams: 2 miller_costa_lima_batista_silva.pdf: 1168809 bytes, checksum: 52a7f74cbe8669231c56555fc6d1ad2b (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>Made available in DSpace on 2018-05-23T18:20:35Z (GMT). No. of bitstreams: 2 miller_costa_lima_batista_silva.pdf: 1168809 bytes, checksum: 52a7f74cbe8669231c56555fc6d1ad2b (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2017-04-10<br>Lipids obtained from microorganisms app

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12

Antoniou, Anna-Mari. "Complying shipping documents under UCP 600." Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/210539/.

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This thesis analyses the Uniform Customs and Practice for Documentary Credits (UCP) against the backdrop of the question: ‘what documents must a beneficiary, acting as seller under an international sale of goods carried by sea, present to a bank, and how must he present them, in order for the presentation to be considered compliant?’. It interprets the rules through the answer to this question by looking at national law but also the range of supporting material published by the International Chamber of Commerce. This includes the International Standard Banking Practice, Banking Commission Opin

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13

Esteves, Pauline. "Etude de l’action anti-tumorale de la protéine mitochondriale UCP2." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05T024.

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Les cellules tumorales sont caractérisées par un métabolisme hautement glycolytique à l’inverse des cellules normales qui utilisent préférentiellement un métabolisme oxydatif. Cette adaptation métabolique permet aux cellules d’être moins dépendantes de l’oxygène et favorise les processus d’invasion. D’autres mécanismes associés aux espèces réactives de l’oxygène qui induisent des dommages de l’ADN contribuent à la transformation cellulaire et à l’initiation tumorale. Le transporteur mitochondrial UCP2 est le deuxième membre identifié dans la famille des UCP dont la fonction mitochondriale rest

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14

Newman, Michael John 1976. "Design and control of a Universal Custom Power Conditioner (UCPC)." Monash University, Dept. of Electrical and Computer Systems Engineering, 2003. http://arrow.monash.edu.au/hdl/1959.1/5651.

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15

Kwok, Hon-hung Ken, and 郭漢洪. "The role of UCP5 in mitochondrial dysfunction in Parkinsonian models." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41508233.

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16

Rouger, Laurie. "Implication de la protéine Mitochondriale UCP2 dans la réponse immunitaire." Thesis, Université Laval, 2008. http://www.theses.ulaval.ca/2008/25244/25244.pdf.

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17

Alves-Guerra, Marie-Clotilde. "Le rôle anti-oxydant de la protéine découplante mitochondriale UCP2." Paris 11, 2003. http://www.theses.fr/2003PA11TO49.

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18

Kwok, Hon-hung Ken. "The role of UCP5 in mitochondrial dysfunction in Parkinsonian models." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41508233.

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19

Rousset, Sophie. "La protéine découplante mitochondriale UCP2 : implications dans la réponse inflammatoire." Paris 11, 2005. http://www.theses.fr/2005PA11T059.

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20

Zhang, Jingbo. "Document examination and rejection under UCP 600." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/378253/.

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Letters of credit, which are a well-recognised payment instrument, have bridged international trade between different countries. The UCP, which is often regarded as “soft regulation” has provided a solid backing for the operation of documentary credits and nowadays the latest revision, UCP600 is universally incorporated into nearly all letters of credit. This thesis focuses on two vital but controversial parts in a documentary credit operation, i.e. document examination and rejection under UCP600. The central research question addressed by this thesis is: Has the UCP600 provided a sufficient f

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21

Kenji, Shiosaki Ricardo. "Aspectos bioquímicos e fisiológicos da biorremoção de pireno por Rhizopus arrhizus UCP 402 e R. arrhizus UCP 402X (mutante)." Universidade Federal de Pernambuco, 2004. https://repositorio.ufpe.br/handle/123456789/1902.

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Made available in DSpace on 2014-06-12T15:53:04Z (GMT). No. of bitstreams: 2 arquivo5098_1.pdf: 917807 bytes, checksum: 66a5977f89199b35877ba7324a3e991f (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2004<br>Os fungos da ordem Mucorales têm se destacado pelo seu excelente potencial biológico na eliminação de contaminantes tóxicos do ambiente. Investigações foram realizadas no sentido de utilizar processos de biorremediação para a remoção de pireno por Rhizopus arrhizus. Estudos iniciais foram realizados para obtenção de um mutante fisi

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22

Lin, Jian-Man. "Islet insulin secretory patterns in diabetes and the role of UCP2." Doctoral thesis, Uppsala University, Department of Medical Cell Biology, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2989.

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<p>During development of type 1 and type 2 diabetes plasma insulin patterns are altered. Since the islet insulin release pattern has been implicated in this development, insulin secretion from single islets was studied and linked to the islet protein levels of uncoupling protein-2 (UCP2). Islets were isolated from NOD- and KKA<sup>y</sup>- mice, GK- and GK-derived congenic rats, which are animal models of diabetes, and three human subjects with type 2 diabetes. At basal glucose (3 mM), insulin release from such islets was pulsatile and the amount released was comparable to that of control isle

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23

Chu, Chi-yuen Andrew. "A study on mitochondrial uncoupling protein 4 (UCP4) in Parkinsonian models." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B39634449.

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24

Chu, Chi-yuen Andrew, and 朱志遠. "A study on mitochondrial uncoupling protein 4 (UCP4) in Parkinsonian models." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39634449.

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25

MORAES, FILHO Marcos Antônio de. "Avaliação do potencial biotecnológico de Phanerochaete chrysosporium UCP 963 e Cunninghamella elegans UCP 596 na remoção de cobre e zinco." Universidade Federal de Pernambuco, 2005. https://repositorio.ufpe.br/handle/123456789/799.

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Made available in DSpace on 2014-06-12T15:05:32Z (GMT). No. of bitstreams: 2 arquivo4553_1.pdf: 555608 bytes, checksum: 9cb94ebf40323d8ad913699e17a82f12 (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2005<br>Investigações foram realizadas comparativamente sobre a habilidade de biossorção de cobre e zinco pela biomassa de Phanerochaete chrysosporium UCP 963 e Cunninghamella elegans UCP 596. A remoção dos metais pesados foi avaliada utilizando-se diferentes quantidades de biomassa (120 mg e 240 mg), viva e inativada, adicionadas a so

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26

Daňo, Peter. "Dokumentárny akreditív a zmeny vyvolané revíziou UCP 600." Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-4905.

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Práce charakterizuje dokumentární akreditiv jako jeden z významných platebních a zajišťovacích instrumentů v mezinárodním obchodě. V jednotlivých kapitolách jsou uvedené výhody a nevýhody jeho použití, typy dokumentárních akreditivů, použitelnost akreditivu a dokumenty používané při akreditivních operacích. Poslední kapitola je zaměřená na eUCP, elektronický akreditiv a systémy elektronického akreditivu.

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27

Pedraza, González Neus. "Estudi de la regulació transcripcional del gen de la proteïna desacobladora UCP3." Doctoral thesis, Universitat de Barcelona, 2004. http://hdl.handle.net/10803/2987.

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El gen <i>UCP3</i> s'expressa majoritàriament al múscul esquelètic i al TAM en rosegadors, i pràcticament de manera exclusiva al múscul esquelètic en humans. El gen s'activa en resposta a diferents estímuls, entre els quals trobem l'àcid retinoic, els àcids grassos no esterificats i les hormones tiroïdals. L'estudi de la regulació de la transcripció del gen <i>UCP3</i> en cèl·lules musculars ens ha permès obtenir informació sobre els mecanismes moleculars responsables de l'expressió d'<i>UCP3</i> al múscul esquelètic i de la modulació d'aquesta expressió deguda als estímuls esmentats. L'estud

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28

Modas, Diana Andreia Santos. "Cuidados de enfermagem ao cliente internado na UCPA submetido a cateterização vesical." Master's thesis, Instituto Politécnico de Setúbal. Escola Superior de Saúde, 2016. http://hdl.handle.net/10400.26/14233.

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Relatório de Trabalho de Projeto apresentado para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Enfermagem Médico-Cirúrgica<br>O presente documento reporta ao relatório de trabalho de projeto realizado no âmbito do curso de Mestrado em Enfermagem Médico-Cirúrgica (EMC), que contempla o Projeto de Intervenção em Serviço (PIS), englobando a metodologia de projeto, o qual consistiu na elaboração da Norma de Procedimento (NP) relativa aos cuidados de enfermagem ao cliente na cateterização vesical na Unidade de Cuidados Pós-Anestésicos (UCPA), suportada na evidência científ

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29

McBride, Skye. "Elucidating a Role for UCP3 in the Control of Mitochondrial Superoxide Flashes." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31588.

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Mitochondria are a major site of reactive oxygen species (ROS) production in cells. While ROS can cause oxidative damage, they are vital in many signaling processes. Recently, mitochondrial superoxide flashes (mSOF) were defined through sensitive measurements of temporal and spatial differences in superoxide production. mSOF are stochastic events of quantal bursts in superoxide production, which are temporally linked to transient mitochondrial inner membrane depolarizations. The aims of the present study were to characterize a hydrogen peroxide sensitive biosensor to monitor these events and e

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30

Roy, Marie-Claude. "Implication de la protéine découplante 2 (UCP2) dans la réponse au stress." Thesis, Université Laval, 2014. http://www.theses.ulaval.ca/2014/30788/30788.pdf.

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Les protéines découplantes (UCPs) sont situées dans la membrane interne des mitochondries. La première découverte, UCP1, est connue pour son potentiel à découpler la synthèse de l’adénosine 5’ triphosphate (ATP) de l’oxydation des substrats énergétiques, ce qui entraîne une accélération du métabolisme et une production de chaleur. La protéine découplante 2 (UCP2), est distribuée de façon ubiquitaire et semble plutôt réguler la production des espèces réactives de l’oxygène (ROS) et l’utilisation des substrats énergétiques. À notre connaissance, le rôle d’UCP2 dans les différents segments de l’a

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31

Piel, Mathilde. "Les bases moléculaires de la thermogenèse induite par la protéine découplante UCP1." Thesis, Université de Paris (2019-....), 2019. http://www.theses.fr/2019UNIP7025.

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La protéine découplante UCP1 est localisée dans la membrane interne des mitochondries du tissu adipeux brun. Elle fait partie de la famille des transporteurs mitochondriaux (SLC25). En présence d’acide gras à chaîne longue, UCP1 permet le passage des protons de l’espace intermembranaire vers la matrice, découplant ainsi la chaîne respiratoire de la production d’ATP. Ceci provoque un emballement de l’oxydation des substrats dans la mitochondrie et mène à la production de chaleur. Plusieurs mécanismes ont été proposés pour expliquer la conductance aux protons provoquée par l’ajout d’acides gras

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32

Liu, Qian. "The role of C/EBPbeta in regulating UCP1 expressions in 3T3-L1 adipocytes." Thesis, University of Nottingham, 2012. http://eprints.nottingham.ac.uk/12469/.

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Uncoupling protein 1 (UCP1) is essential for non-shivering thermogenesis in brown adipose tissue (BAT) by dissipating proton-motive force to stimulate maximum mitochondrial respiration. cAMP-dependent protein kinase induction of UCP1, as well as the PPAR coactivator1α (PGC1α), is a typical characteristic in BAT but not in white adipose tissue (WAT). Previous work demonstrated that the overexpression of CCAAT/Enhancer Binding Protein β (C/EBPβ) could rescue the cAMP-induced PGC1α and UCP1 expression in white preadipocytes 3T3-L1 cell line, indicating a key regulatory role of C/EBPβ in brown adi

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33

Green, K. "UCP2 in pancreatic beta-cells : a radical way to short circuit glucose sensing?" Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599662.

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Uncoupling proteins (UCPs) catalyse proton transport across the mitochondrial inner membrane, thereby uncoupling oxidative phosphorylation. UCP2 is expressed in several mammalian tissues including pancreatic β-cells. Since UCP2 activity uncouples the processes that link glucose metabolism (oxidation) to insulin secretion (phosphorylation), it is expected to attenuate glucose-stimulated insulin secretion (GSIS). Published studies using UCP2 over-expressing and UCP2 ablated β-cells support this hypothesis. Therefore, identifying regulators of β-cell UCP2 activity may help develop novel ways to t

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34

Aheng, Marie-Caroline. "Etude de la protéine mitochondriale UCP2 au cours de l'encéphalite auto-immune expérimentale." Paris 6, 2010. http://www.theses.fr/2010PA066106.

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La protéine découplante UCP2 fait partie de la famille des transporteurs mitochondriaux. Son expression prédomine dans les cellules immunitaires. Chez la souris, le gène est situé dans une région chromosomique fortement associée à l’Encéphalite Auto-immune Expérimentale (EAE), un modèle murin de sclérose en plaques (SEP). En absence d’UCP2, la réponse auto-immune est amplifiée. Sur le plan clinique, cela se traduit par des troubles moteurs beaucoup plus sévères. Le but de ce travail était, dans un premier temps, de comprendre les relations entre UCP2 et la NO synthase inductible (iNOS), une en

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Brondani, Letícia de Almeida. "Polimorfismo -3826A/G no gene UCP1 : investigação de sua possível associação com retinopatia diabética em pacientes com diabetes mellitus tipo 1 e de seu efeito na expressão da UCP1 na retina." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/32860.

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Está bem definido que fatores genéticos têm um papel importante no desenvolvimento do diabetes mellitus (DM) e de suas complicações crônicas. Sendo assim, grandes esforços têm sido feitos para se identificar os genes associados com estas doenças. A proteína desacopladora 1 (UCP1), principalmente expressa no tecido adiposo marrom, desacopla a oxidação dos substratos da síntese de ATP pela ATPsintase, dessa forma, dissipando o potencial de membrana e, consequentemente, diminuindo a produção de ATP pela cadeia respiratória mitocondrial. Esse desacoplamento então leva à regulação do gasto energéti

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Ryan, Orna. "Modularisation at UCD : an exploration of governance in higher education." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/5795.

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Rizvi and Lingard (2010) suggest that there have been shifts in the development and institutional implementation of education policies, as the values promoted by national systems of education are not just established by the policy actors within the nation state but forged through transnational and global entities. In current studies, there are a number of reductionist accounts of global effects on education policy which do not take account of historical context. Drawing on the policy sociology literature, this thesis empirically investigates the policy process at University College Dublin when

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Pecqueur-Hellman, Claire. "Une nouvelle protéine découplant mitochondriale UCP2 : le gène, la protéine et ses rôles physiologiques." Paris 11, 2000. http://www.theses.fr/2000PA11T047.

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La protéine découplante UCP2 est une protéine mitochondriale exprimée dans de nombreux tissus. Les variations du niveau d'expression de l'ARNm UCP2 observées dans certaines situations physiologiques suggéraient l'existence d'une régulation transcriptionnelle. Le clonage du gène humain a permis de mettre en évidence un promoteur riche en bases GC, ne comportant ni boîte TATA, ni boîte CAAT. Des transfections transitoires dans une lignée d'adipocytes bruns avec des constructions CAT ont permis de mettre en évidence une activité promotrice relativement forte. La mise en évidence d'une ORF1 dans l

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Ana, Yuliana. "Study on the regulatory mechanism for Uncoupling protein 1 (Ucp1) expression in beige adipocytes." Kyoto University, 2019. http://hdl.handle.net/2433/244554.

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Monteiro, Tatiana Cavalcanti. "Pontos de caso de uso técnicos (TUCP) : uma extensão da UCP." Universidade de Fortaleza, 2005. http://dspace.unifor.br/handle/tede/69800.

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Made available in DSpace on 2019-04-05T23:04:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2005-08-05<br>The software engineering argues the implantation of activities of size estimates, effort, period and cost, as forms of improving the software projects planning and tracking. In spite of there being several techniques of estimates, the use of the same ones in software companies is not still such a common practice. The technique UCP (Use Case Points), for instance, it is adherent to object-oriented software products and based on use cases. However, they have been finding some situati

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Cristina, Lapenda Lins Jeanne. "Produção e caracterização de prodigiosina isolada de Serratia marcescens UCP 1549." Universidade Federal de Pernambuco, 2010. https://repositorio.ufpe.br/handle/123456789/1725.

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Made available in DSpace on 2014-06-12T15:52:02Z (GMT). No. of bitstreams: 2 arquivo2808_1.pdf: 3862930 bytes, checksum: e749256848081d690dbce7c04ef3958f (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2010<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>Prodigiosinas é uma família de pigmentos naturais, de cor vermelha caracterizado por um esqueleto comum pirrolilpirrometano, produzido por várias bactérias, porém primeiro produzido por Serratia marcescens. Este pigmento é uma droga promissora, devido às suas caracterí

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Espinoza, Jorge, Pamela Loarte, Carlos Espinoza, Freddy Paz, and Juan Arenas. "A new software development model: Innovation through mobile application with UCD." Springer Verlag, 2018. http://hdl.handle.net/10757/624691.

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El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.<br>Pursuit of innovation projects with the absent of a methodology to follow hampers the development of the software product as its complexity grows since the freedom of its own advancement is confused with the lack of order on it. Traditional and agile methodologies do not adapt to this kind of projects therefore, in this paper we aim to design a model that incorporates characteristics of both of them to get a solution of a need found in society.

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Varatharajah, Thujeepan. "Integrating UCD with Agile Methods : From the perspective of UX-Designers." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-262705.

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With the increasing popularity of Agile methods in software development projects, an emerging question is how Agile incorporates user needs to their process – which is the staple of User Centered Design (UCD). Existing reports indicate that integrating Agile and UCD has shown to improve the process and end product and that they are a natural fit. However, there is also a general lack of guidelines of how an effective integration may be done, and further research is requested. This study aims to provide that by portraying some aspects of how Agile and UCD may be integrated in practice, but also

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Emre, Yalin. "Influence de la protéine découplante mitochondriale UCP2 sur la signalisation et le métabolisme des macrophages." Phd thesis, Université René Descartes - Paris V, 2007. http://tel.archives-ouvertes.fr/tel-00182672.

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La protéine UCP2 (UnCoupling Protein 2) appartient à la famille des transporteurs de la membrane interne de la mitochondrie. Son expression est restreinte à certains tissus comme la rate, l'estomac ou l'intestin. Au niveau cellulaire, UCP2 est particulièrement présente dans les macrophages où elle régule la production de radicaux libres (ROS). L'analyse des souris Ucp2-KO a montré qu'elles survivent mieux à une infection par le parasite Toxoplasma gondii que les animaux sauvages grâce à des macrophages superactifs en terme de production de ROS. Par ailleurs, dans le modèle murin de l'athéroscl

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Siepen, Maria [Verfasser]. "Die Bedeutung des mitochondrialen Proteins UCP2 in der Ausbildung eines Myokardinfarktes im Mausmodell / Maria Siepen." Köln : Deutsche Zentralbibliothek für Medizin, 2015. http://d-nb.info/1079848118/34.

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Silva, Diana Perin da. "Efeitos do polimorfismo -866g/a no gene ucp2 sobre respostas metabólicas agudas ao exercício aeróbio." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2011. http://hdl.handle.net/10183/85186.

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Proteínas desacopladoras (UCPs) estão presentes na membrana mitocondrial interna e por meio do transporte de prótons do espaço intermembranas para a matriz mitocondrial desacoplam a oxidação dos substratos da síntese de ATP, dissipando a energia do potencial de membrana e, conseqüentemente, diminuindo a produção de ATP pela cadeia respiratória mitocondrial. O aumento na expressão de UCP2 está relacionado com um risco diminuído de obesidade e risco aumentado de desenvolvimento de diabetes melito. O polimorfismo - 866G/A na região promotora do gene da UCP2 está associado a um aumento da expressã

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FLEURY, CHRISTOPHE. "Etude fonctionnelle des proteines decouplantes mitochondriales (ucps) par expression heterologue dans la levure saccharomyces cerevisiae." Paris 11, 1998. http://www.theses.fr/1998PA112237.

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La proteine ucp1 (uncoupling protein-1) est un transporteur dans la membrane interne mitochondriale, specifique des adipocytes bruns thermogeniques. Ucp1 permet la rentree des protons dans la matrice mitochondriale et dissipe le gradient de protons genere par la chaine respiratoire. L'energie liberee par ce decouplage entre la respiration cellulaire et la phosphorylation de l'atp est dissipee sous forme de chaleur. Cette activite decouplante est inhibee par les nucleotides et activee par les acides gras libres. L'etude fonctionnelle d'ucp1 par expression heterologue dans la levure saccharomyce

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Hurtaud, Corinne. "Contrôle de la traduction d' UCP2 : mise en évidence d' une régulation par la glutamine." Paris 7, 2005. http://www.theses.fr/2005PA077100.

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Ozcelik, Ozgur. "A mechanics-based virtual model of NEES-UCSD shake table theoretical development and experimental validation /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3320217.

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Thesis (Ph. D.)--University of California, San Diego, 2008.<br>Title from first page of PDF file (viewed September 22, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.

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MILANESI, SILVIA. "IL GRUPPO LOMBARDO DELL'UNIONE CRISTIANA IMPRENDITORI DIRIGENTI (UCID), DALLA FONDAZIONE (1945) AI PRIMI ANNI '70." Doctoral thesis, Università Cattolica del Sacro Cuore, 2019. http://hdl.handle.net/10280/61870.

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Il Gruppo Lombardo dell’UCID fu costituito a Milano l’11 maggio 1945 per iniziativa di uomini provenienti dall’ambiente dell’Azione Cattolica, del SEDAS e dell’ICAS, nonché importanti esponenti dell’imprenditoria, del management e del mondo bancario lombardo e milanese del tempo. Scopo primo dell’Associazione era “formare gli aderenti ai principi della morale professionale e […] promuovere l’attuazione del pensiero sociale nel campo dell’industria e del lavoro”. Il Gruppo Lombardo è stato studiato con riferimento al periodo compreso tra la sua costituzione e la fine degli anni Sessanta/primi S

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MILANESI, SILVIA. "IL GRUPPO LOMBARDO DELL'UNIONE CRISTIANA IMPRENDITORI DIRIGENTI (UCID), DALLA FONDAZIONE (1945) AI PRIMI ANNI '70." Doctoral thesis, Università Cattolica del Sacro Cuore, 2019. http://hdl.handle.net/10280/61870.

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Il Gruppo Lombardo dell’UCID fu costituito a Milano l’11 maggio 1945 per iniziativa di uomini provenienti dall’ambiente dell’Azione Cattolica, del SEDAS e dell’ICAS, nonché importanti esponenti dell’imprenditoria, del management e del mondo bancario lombardo e milanese del tempo. Scopo primo dell’Associazione era “formare gli aderenti ai principi della morale professionale e […] promuovere l’attuazione del pensiero sociale nel campo dell’industria e del lavoro”. Il Gruppo Lombardo è stato studiato con riferimento al periodo compreso tra la sua costituzione e la fine degli anni Sessanta/primi S

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