Дисертації з теми "T385"

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1

Pharasi, Bhuwan. "Murray polygons as a tool in image processing." Thesis, University of St Andrews, 1990. http://hdl.handle.net/10023/13580.

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This thesis reports on some applications of murray polygons, which are a generalization of space filling curves and of Peano polygons in particular, to process digital image data. Murray techniques have been used on 2-dimensional and 3-dimensional images, which are in cartesian/polar co-ordinates. Attempts have been made to resolve many associated aspects of image processing, such as connected components labelling, hidden surface removal, scaling, shading, set operations, smoothing, superimposition of images, and scan conversion. Initially different techniques which involve quadtree, octree, and linear run length encoding, for processing images are reviewed. Several image processing problems which are solved using different techniques are described in detail. The steps of the development from Peano polygons via multiple radix arithmetic to murray polygons is described. The outline of a software implementation of the basic and fast algorithms are given and some hints for a hardware implementation are described The application of murray polygons to scan arbitrary images is explained. The use of murray run length encodings to resolve some image processing problems is described. The problem of finding connected components, scaling an image, hidden surface removal, shading, set operations, superimposition of images, and scan conversion are discussed. Most of the operations described in this work are on murray run lengths. Some operations on the images themselves are explained. The results obtained by using murray scan techniques are compared with those obtained by using standard methods such as linear scans, quadtrees, and octrees. All the algorithms obtained using murray scan techniques are finally presented in a menu format work bench. Algorithms are coded in PS-algol and the C language.
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2

Taylor, Mark W. "Special finite elements for modelling adhesively bonded joints in two- and three-dimensions." Thesis, This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-12232009-020637/.

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3

Tate, Deborah F. "Promoting exercise adoption through computer networks." Thesis, This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-12232009-020633/.

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4

Tappert, Peter M. "Damage identification using inductive learning." Thesis, This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-05092009-040651/.

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5

Tavenner, Cloyd Tallman. "FAIRSHARE:an investigation into driving a pay for performance system with the multi-criteria measurement technique." Master's thesis, Virginia Tech, 1991. http://hdl.handle.net/10919/40609.

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6

Liu, Ta-Ming. "Kinase Targeting Therapies in Chronic Lymphocytic Leukemia: Mechanisms of Acquired Ibrutinib Resistance and the Pre-Clinical Development of OSU-T315." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1404917090.

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7

Tatarka, Bernadette. "Relationships among body-self relations, exercise involvement, and exercise clothing attitude for women in regular exercise programs." Diss., This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-06062008-162917/.

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8

Taylor, Delana. "Cytoskeletal changes in SY5Y neuroblastoma cells exposed to acrylamide : an immunocytochemical study /." Thesis, This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-07102009-040505/.

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9

Tabisz, Wojciech Antoni. "High-frequency multi-resonant power conversion techniques." Diss., Virginia Tech, 1990. http://hdl.handle.net/10919/37404.

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10

Tankel, Jesslyn Elise. "A Teaching Toy: Free Forms in an Abstract Landscape." Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/45220.

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As a young student, I enjoyed a passion for the studio arts and an interest in art history. I ardently pursued these areas in college, continuing their exploration in graduate school in the field of Industrial Design. For the thesis project, my objective is to foster in children an appreciation for art and, possibly, to help them develop a critical and appreciative eye toward their environment. In my research, I find inspiration in child psychology and the toys of child's play, in 15th-century Islamic art and 20th-century Abstraction, and in naturally occurring events such as ivy twisting up a knotty tree trunk and soft ripples in a pond. The assimilation of these elements, together with the ideas that they generate, evolve into the foundation for my project. My intent is to design a toy which provides children ages six to twelve years with insight into both the world of nature and the realm of art. Further, the toy will heighten each child's visual vocabulary to acknowledge the organic, natural line that exists in nature and which is, perhaps, represented in abstract art. These goals are the guiding principles for my work.
Master of Science
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11

Tavakkoli, Shahriar. "Shape design using intrinsic geometry." Diss., Virginia Tech, 1991. http://hdl.handle.net/10919/39421.

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12

Tarrago, Medina Maria Teresa. "Isolation of a human milk sialyloligosaccharide by affinity chromotography with wheat germ agglutinin (WGA)." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/94481.

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Lectin affinity chromatography has been applied to the separation of the sialyloligosaccharides of human milk. A human milk sialyloligosaccharide fraction was tritium labeled and applied to a highly substituted WGA-agarose column (20 mg/ml). Only a single component from the complete sialyloligosaccharide fraction was retarded in the WGA-agarose column. The WGA-bound fraction when applied to paper chromatography migrated with identical mobility as the sialylhexasaccharide fraction (S-5) of human milk, previously isolated and described by Kobata and Ginsburg in 1972 [Arch. Biochem. Biophys., 150:273-281]. A purified sialylhexasaccharide fraction (S-5), isolated according to the method of Kobata and Ginsburg, was radiolabeled and applied to the WGA-agarose column. The WGA-bound (60%) and WGA-unbound (40%) sialylhexasaccharide fractions were isolated. The WGA-bound sialylhexasaccharide fraction was subjected to neuraminidase digestion to remove sialic acid, and the resulting neutral oligosaccharide had more affinity for the WGA-agarose column. Sequential exoglycosidase digestion of the asialo derivative of the WGA-bound fraction with jack bean β -galactosidase and β -hexosaminidase demonstrated the presence of a lacto-N-neohexaose core. The position of sialic acid in the sialyllacto-N-neohexaose was determined by simultaneous digestion of the sialylhexaose with jack bean β -galactosidase and β -hexosaminidase, which removed the non-sialylated branch from the sialylhexaose and produced a sialyltetraose. The sialyltetraose was found to be sialyltetrasaccharide c as demonstrated by its elution time on HPLC and direct binding to monospecific anti-sialyltetrasccharide c serum. The structural data indicated that the WGA-bound sialylhexaose is a sialyl derivative of lacto-N-neohexaose with sialic acid linked to the 3 branch of this core structure which represents a previously undescribed sialyloligosaccharide in human milk. The structure of the WGA-bound sialylhexaose is,
M.S.
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13

Tarrago-Trani, Maria T. "Isolation of a human milk sialyloligosaccharide by affinity chromotography with wheat germ agglutinin (WGA)." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/94481.

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Анотація:
Lectin affinity chromatography has been applied to the separation of the sialyloligosaccharides of human milk. A human milk sialyloligosaccharide fraction was tritium labeled and applied to a highly substituted WGA-agarose column (20 mg/ml). Only a single component from the complete sialyloligosaccharide fraction was retarded in the WGA-agarose column. The WGA-bound fraction when applied to paper chromatography migrated with identical mobility as the sialylhexasaccharide fraction (S-5) of human milk, previously isolated and described by Kobata and Ginsburg in 1972 [Arch. Biochem. Biophys., 150:273-281]. A purified sialylhexasaccharide fraction (S-5), isolated according to the method of Kobata and Ginsburg, was radiolabeled and applied to the WGA-agarose column. The WGA-bound (60%) and WGA-unbound (40%) sialylhexasaccharide fractions were isolated. The WGA-bound sialylhexasaccharide fraction was subjected to neuraminidase digestion to remove sialic acid, and the resulting neutral oligosaccharide had more affinity for the WGA-agarose column. Sequential exoglycosidase digestion of the asialo derivative of the WGA-bound fraction with jack bean β -galactosidase and β -hexosaminidase demonstrated the presence of a lacto-N-neohexaose core. The position of sialic acid in the sialyllacto-N-neohexaose was determined by simultaneous digestion of the sialylhexaose with jack bean β -galactosidase and β -hexosaminidase, which removed the non-sialylated branch from the sialylhexaose and produced a sialyltetraose. The sialyltetraose was found to be sialyltetrasaccharide c as demonstrated by its elution time on HPLC and direct binding to monospecific anti-sialyltetrasccharide c serum. The structural data indicated that the WGA-bound sialylhexaose is a sialyl derivative of lacto-N-neohexaose with sialic acid linked to the 3 branch of this core structure which represents a previously undescribed sialyloligosaccharide in human milk. The structure of the WGA-bound sialylhexaose is,
M.S.
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14

Théberge, Antoine. "Société civile, une réalité à l'étroi [sic] dans son concept." Master's thesis, Université Laval, 2010. http://hdl.handle.net/20.500.11794/22041.

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Pourquoi une réflexion sur la société civile? Parce que depuis quelques années on assiste à un retour du concept. Presqu'oubliée au long du XXe siècle, elle est maintenant porteuse de grands espoirs; se présentant sous ces nouvelles formes de solidarité qui émergent, elle révèle une importante force de démocratisation. Deux causes viennent rapidement à l'esprit pour expliquer son retour: d'un côté la chute des régimes totalitaires communistes à laquelle ont participé les sociétés civiles des pays de l'Est; de l'autre, le phénomène des grandes mobilisations citoyennes qui poussent leurs causes sans passer par les canaux politiques traditionnels et sans égards aux frontières des États. Par contre, malgré le rôle politique de premier plan qu'on lui attribue, malgré que plusieurs l'appellent, l'interpellent ou s'y réfèrent, trop souvert le concept est utilisé sans qu'il sort défini. Et même lorsqu'il l'est, les définitions proposées diffèrent et les désaccords conceptuels demeurent. Bref l'objet reste flou: représente-t-elle un phénomène de génération spontané ou la manifestation récente d'une tendance ancrée dans l'histoire? Est-elle une simple marchandise politique ou le terreau démocratique du XXIe siècle? La réflexion proposée cernera d'abord l'ampleur du phénomène et les difficultés liées à la notion avant de s'attarder aux événements ayant ramené l'expression. Nous cheminerons en puisant autant dans la politique, l'économie que dans la sociologie comme telle mais également dans la philosophie puisque trouvant son fondement dans le riche héritage qu'ont légué ceux qu'on peut appeler les pères du concept, l'essai s'intéressera de phis près aux contributions de Rousseau, Smith, mais Hegel surtout, pour ensuite interpeller Gramsci, ce penseur marxiste de la modernité qui, partant de Hegel, a repris et réactualisé la catégorie. C'est par ce détour que notre réflexion se donnera les assises lui permettant de s'attaquer à la théorie phare de la société civile qu'Andrew Arato et Jean L. Cohen ont développée dans leur ouvrage, devenu référence, Civil Society and Political Theory (1992). Suivant leur réflexion nous répondrons à trois questions structurelles fondamentales pour la catégorie. Premièrement, à ceux qui le remettaient en question, nous verrons que, malgré quelques ajustements, Hegel fourni toujours un cadre conceptuel adéquat à la compréhension de notre objet. Puis nous réfléchirons à la place de la société civile par rapport au marché, et finalement aux liens qu'elle entretient avec la société politique.
Cette démarche sera bienvenue puisque trop souvent sont esquivées les prémisses conceptuelles, références théoriques et bases historiques indispensables. C'est pour y remédier que nous prendrons ainsi le temps de mobiliser autant les théoriciens plus anciens du XVIIe, XVIIIe et XIXe qui ont forgé le concept, que les auteurs modernes et contemporains. Empruntant ce détour par les "anciens", nous éclairerons les multiples significations dont le concept a été dépositaire, puis dégagerons, à l'aide des recoupements et filiations trouvés entre auteurs, les acquis les plus fermes. Proposé comme effort de synthèse, ce mémoire qui explorera autant les racines que les nouveaux aspects du concept, aspire évidemment à mieux en cerner les contours et à faciliter la compréhension de sa théorie mais plus encore, à penser adéquatement cette "chose nouvelle". Catégorie particulièrement équivoque en théorie politique et sociale, nous chercherons ce dénominateur commun qui permettra d'ériger un pont entre ce que le concept traîne avec lui et ce qui s'y colle aujourd'hui Au-delà du produit composite des cheminements militants, il devrait être possible d'élaborer une réflexion pouvant ancrer ce qui finalement reste une discussion commune outrepassant les frontières temporelles et physiques. Quel intérêt et quelle pertinence sociologique cette démarche peut-elle avoir? Descriptive, théorique et analytique, elle permettra d'abord en s'attardant principalement au concept de dissiper le flou l'entourant, de mieux en saisir et en apprécier l'immense potentiel, puis... de prendre position. Voilà, serait-il possible que ce nouveau phénomène ne soit ni tout à fait un phénomène de génération spontané, ni non plus entièrement la manifestation récente d'une tendance ancrée dans l'histoire? Serait-il possible que dans un certain sens cette "chose nouvelle" soit mal nommée? Clair auparavant, le concept utilisé pour la désigner, où nouveauté et continuité bataillent, devient flou. Et justement, le phénomène récent de mobilisation que nous observons s'y empêtre. Comment penser adéquatement cette conscience globale s'attaquant au problème local, ce phénomène d'influence économique qui n'est pas marchand, ce nouveau rapport au politique qui ne fait phis l'arrêt par la politique? En établissant un cadre commun entre les différentes réalités nationales, nous dépasserons l'image de simple marchandise politique que d'aucuns collent au concept et la présenterons comme véritable force démocratique, mais pour lui redonner toute sa valeur nous devrons libérer la chose du mot qui la défini en travaillant cette asymétrie révélée entre ses racines historiques et la forme qu'elle prend à désigner ce monde d'alternatives. Pour outrepasser les frontières physiques autant que temporelles du concept nous devrons mettre en lumière la dimension communautaire et dégager ces nouvelles formes de solidarité qui apparaissent maintenant mais qui se situent à un autre niveau que celui décrit par Hegel d'une totalité citoyenne vécue à l'intérieur de l'État. Bref, à travers ces nouveaux phénomènes d'opposition ou de résistance c'est l'aspect de mobilisation, la dimension de la solidarité, de ces nouvelles formes de solidarité, qui garantira une cohésion conceptuelle et qu'il faudra mettre en valeur.
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15

Tate, Andrew E. "Maturation, spawning and fertility of hybrid striped bass (Morone chrysops x Morone saxatilis) exposed to 6- and 9-month photothermal cycles." Thesis, This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-02132009-170956/.

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16

Tasissa, Gudaye. "Modeling thinning effects on ring width distribution and wood specific gravity of loblolly pine (Pinus taeda L.)." Diss., This resource online, 1996. http://scholar.lib.vt.edu/theses/available/etd-06062008-145022/.

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17

Tackett, Jared Franklin. "Directing Movement and the Perception of Space." Thesis, Virginia Tech, 2009. http://hdl.handle.net/10919/33437.

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An investigation on how architectural elements can direct movement and affect the way we perceive space. The idea is implemented in the design of a playground and pavilion for Elkhorn Lake, located in Jenkins, Kentucky. Wall, column, color, roof, and floor are explored to create a variety of spatial arrangements that affect ways of perceiving and moving through the pavilion and playground.
Master of Architecture
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18

Tatem, Joseph Edward. ""ENGRAVE - An expert system that understands and generates musical notation"." Thesis, Virginia Tech, 1987. http://hdl.handle.net/10919/43378.

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19

Tatis, Anabel G. "The toxic effects of the pesticide lindane on the early developmental stages of the fathead minnow." Thesis, Virginia Tech, 1990. http://hdl.handle.net/10919/42196.

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Toxic effects of the pesticide Lindane on the eggs, yolksac fry and larvae of the fathead minnow (Pimephales promelas) were investigated over 14 days at 25 and 18°C. The general objective was to understand the effects of the pesticide on the early life stages of the fish, and to evaluate the suitability of these stages as indicators of contaminated environments. Egg, yolk-sac and larval stages that had been exposed to 300, 120, 90, 60, 30, 10, 5, and 0 μg/L of Lindane at 25°C exhibited a 14d-LC₅₀ of 44 μg/L. Similarly, the same stages exposed to 300, 120, 90, 60, 30, 10, and 0 μg/L of Lindane at 18°C exhibited a 14d-LC₅₀ of 37 μg/L. Lower temperature thus seemed to increase the susceptibility of the fish to the pesticide. Mortality data were also used to determine the sensitivity of the early developmental stages of fish to the pesticide. At 25°C, the larval stage was the most sensitive stage. At 18°C, on the other hand, the most sensitive stage was the yolk-sac. Results obtained from experiments in which Lindane doses were applied at different intervals within the 14d-period supported these observations. Low temperatures had a marked effect on the sensitivity of the fathead minnow to Lindane. Embryos exposed to Lindane at 18°C showed different temporal distribution of mortality than those at 25°C. A delay in hatching and emergence of smaller larvae were also noted at 18°C. Lordoscoliosis, edemas and hemorrhages were the most common morphological changes induced by the pesticide during the larval stage. The frequency of these abnormalities was linearly related to doses of Lindane. Impaired swimming behavior was also noted, but it was not related to dosages.
Master of Science
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20

Tatem, James E. "Automatic image analysis methods for use with local operators." Thesis, This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-05092009-040743/.

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21

Taylor, Lynn Elizabeth. "Acid-base regulation during sprint exercise in horses fed lecithin." Diss., This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-06062008-163251/.

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22

Taiyabi, Asif A. "A multi-attribute analysis of nuclear waste disposal alternatives." Master's thesis, This resource online, 1991. http://scholar.lib.vt.edu/theses/available/etd-02022010-020127/.

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23

Taylor, Jonathan Lorin. "Lines of Discovery." Thesis, Virginia Tech, 2004. http://hdl.handle.net/10919/35461.

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An entry for the World Trade Center Memorial Competition was expanded upon as a study into the nature of design. The project influenced its own evolution and revealed exciting outcomes. The memorial is a reinforced concrete tower with an acrylic water tank at the top. The water tank acts as a prism casting colorful light displays both in the tower and around the site. The tank is also the source for continually falling droplets of water. The drops fall 450 feet through an open chamber to land in a shallow overflowing pool and then wash over a stone sepulcher containing the unidentified remains of victims.
Master of Architecture
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24

Tao, Dongping. "A comprehensive study of the electrochemistry and floatibility of pyrite in coal flotation." Diss., This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-11182008-063055/.

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25

Texier, Anne. "The fabrication of carbon-fiber composites by aqueous suspension prepregging with larc-tpi and peek." Thesis, This resource online, 1991. http://scholar.lib.vt.edu/theses/available/etd-03172010-020638/.

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26

Taylor, Linda Diane. "A descriptive study of special education costs to local education agencies and program administrators' perceptions of quality in self-contained and regional programs for seriously emotionally disturbed students in the Hampton Roads area of Virginia." Diss., This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-07282008-135932/.

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27

Taan, Aly H. "A wall within a wall." Thesis, Virginia Polytechnic Institute and State University, 1990. http://hdl.handle.net/10919/53277.

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28

Taylor, Alfred O. "Black engineering and science student dropouts at the University of the District of Columbia from 1987 to 1991." Diss., Virginia Tech, 1994. http://hdl.handle.net/10919/39146.

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29

Théberge, Tommy. "La politique étrangère de la France à l'égard de la "Serbie" et de la "Yougoslavie" entre 1878 et 1995." Master's thesis, Université Laval, 2001. http://hdl.handle.net/20.500.11794/28576.

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30

Taylor, Rita Neville. "Teachers' perceptions of the effects of their collaborative involvement in the school operating plan : a descriptive case study of three schools /." Diss., This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-10042006-143847/.

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31

"3D visibility analysis for visual quality assessment: approaches based on modelling tools, VGE and WebGIS." 2016. http://repository.lib.cuhk.edu.hk/en/item/cuhk-1291457.

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Анотація:
In this thesis, the author has explored the feasibility of 3D visibility analysis for visual quality assessment via the aid of modelling tools, virtual geographic environment (VGE) and WebGIS, which may be beneficial to build a measurable evaluating standard of visual environment in urban open spaces, and referential to create an atmosphere with improved visual comfort in guiding planning or design processing. Considered as long-term significance, 3D visibility analysis for visual quality assessment is potential in enabling the quantitative analysis between urban open spaces and visual perception of human, providing appropriate standard for evaluation of visual environment, and bringing the future urban planning and design fields into rational and reasonable.
Due to the development of 3D modelling software and VGE, their applications have been attempted in 3D visibility analysis by a few previous scholars, exploring the possibility of representation for urban environment in 3D and the feasibility of spatial relationship analysis with visual factors. Lots of progress has been made with the participation of the modelling software such as AutoCAD and 3Ds Max, or analytical platforms such as ArcGIS and VGE. As the extension of preceding study, the author is going to discuss improvements and innovations of some tools applied in visibility analysis and visual quality computation, such as Open Simulator as a VGE Platform. Moreover, due to the easy access for entry-level programmer and the public, Google SketchUp (a type of modelling software) and WebGIS have also been tested whether suitable for the analysis handling, considerably decreasing the programming development difficulty. Both SketchUp and WebGIS are thought to be well accepted by thepublic, as SketchUp has been popularised in 3D modelling and WebGIS has been familiar as the form of websites for a long period, which may enable the dissemination of visibility analysis to the public.
From a pilot study of progresses based on the researches of past scholars, the author developed an improved method for 3D visibility analysis, by mathematically deriving the visual factors from the spatial relationship analysis of buildings, terrain and other geographical features. A few quantitative factors as the distance, solid angle and visual field (a distribution of occupied solid angle in all directions) valued in spherical coordinate system were adopted as the basic units for visibility levels. Starting from the space prototype, the research has also focused on several aspects possibly associated to the visual effects in open spaces, including the openness, enclosure and ground coverage for edge, the distribution and dispersion for skyline, and the visibility of individual building for landmark. For further comparison, the variances of those figures were also noticed during space scales changing for the prototype, in order to find possible connection or changing trend before and after. Moreover, experiments of 3D visibility analysis have been designed and put into practice for real scenes to discover the similarities or differences among prototypical spaces and reality, and Piazza del Campo (Siena, Italy), Piazza San Marco (Venice, Italy) and Olomouc centre area (Olomouc, Czech) have been selected as the first group of candidates. As a complementary study, the central campus area of the Chinese University of Hong Kong (CUHK) were also taken into consideration as an experimental site, for comparison of disparities with those classical scenes. Those would be possible references for conclusion of similarity or discrepancy among various spaces, in order to find out spatial general pattern, or reveal the actual affections of visual factor values in the reality.
在本論文中,作者基於建模工具、虛擬地理環境和网络地理信息系統(WebGIS),對三維可視性分析和視覺評估的可行性進行了探討。概括而言,這項探討將有助於在城市開放空間可評估測量屬性的輔助下實施城市規劃和設計,以期打造具有更佳視覺舒適性的城市環境。而從長遠意義上考量,三維可視性分析和視覺評估亦是實現城市開放空間和視覺感知之間聯繫的定量分析前提,並為城市環境評價提供適當標準,使今後的規劃和設計更趨理性。
由於三維建模軟件和虛擬地理環境的發展,部分學者已在三維可視性分析中進行些許嘗試,試圖了解在城市環境中的三維空間關係與視覺因素進行相關分析的可行性。且在此研究之前,部分實驗已於個別建模軟件如AutoCAD和3ds Max、或分析平台如ArcGIS和虛擬地理環境中取得可觀進展。基於以上前人的成就,筆者一方面期望在分析工具上進行適度革新,另一方面追尋可視性分析和視覺評估算法上改進的可能,從而在本文中做出個人領域上的創新。在此之中,考慮到入門難易程度和公眾接納程度,筆者採納了若干開發難度較低的工具相互搭配,如谷歌草图大师(Google SketchUp,一種輕量級建模軟件)、Open Simulator(虛擬地擬環境平台)和网络地理信息系統,來輔助進行城市開放空間的可視性分析。谷歌草图大师常被用作於平民化的三維建模,Open Simulator可提供形象化的現實模擬和交互環境,而WebGIS以眾人熟知的網站形式進行交互操作,這些工具在大眾中擁有較高的普及程度和較低的接納門檻,同時亦為可視性分析在大眾中普及提供了一定的可能。
而從三維可視性分析的方法改進上,筆者基於先前學者的部分試點研究,在數學推導上對地形、建築物等地理特徵產生空間關係的計算方法提供合理改進。基於球坐標系,作者用距離、球面度和視角分佈(各方向上視角的分佈)等量化數值為城市開放空間進行基本可視單元的度量;亦從空間原型出發,研究集中討論了若干視覺效果,如開放度、圍合度和地面覆蓋度,天際線的分佈和離散程度,個別建築物的可視性分佈等,在城市開放空間可視效果度量上的作用。此外,通過進一步比較各空間之間可視數值上的差異,量化地去理解空間的視覺效果差異,並可依照參數變化的對比尋找可能存在的變化趨勢和相關性,對空間的可視性有更深的理解。
在本論文的實驗中,作者亦採用了部分真實場景進行三維可視性和視覺評估的分析,以期發現與原型空間相似性或差異性。坎波廣場(意大利錫耶納)、聖馬可廣場(意大利威尼斯)和奧洛穆茨中心區域(捷克奧洛穆茨)作為城市經典空間作為第一批實驗場景,而後續的香港中文大學中央校園作為普通場景的對比亦被納入實驗場景之中,以便進行相似性和差異性的探討。採用真實場景的實驗有助於更好地將現實中城市開放空間的視覺特性與演算結果進行結合,揭示各可視數值的實際表現意義,並在空間原型的相似性上進行合理探討。
Lin, Tianpeng.
Thesis Ph.D. Chinese University of Hong Kong 2016.
Includes bibliographical references (leaves 110-116).
Abstracts also in Chinese.
Title from PDF title page (viewed on 05, October, 2016).
Detailed summary in vernacular field only.
Detailed summary in vernacular field only.
Detailed summary in vernacular field only.
Detailed summary in vernacular field only.
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32

Lin, Shih-Wei, and 林仕偉. "T315 Induces G2/M Cell Cycle Arrest in Oral Squamous Carcinoma Cells." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/mv5q9t.

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Анотація:
碩士
中國醫藥大學
生物科技學系碩士班
101
Oral squamous cell carcinoma is the main malignant neoplasm of the oral cavity and the fifth most common cancer worldwide, with variations in its global incidence. Integrin-linked kinase (ILK) overexpression has been associated with the oncogenesis and tumor progression of many types of malignancies. ILK is a β1-integrin cytoplasmic domain interacting protein, and functions as a scaffold in forming multiprotein complexes connecting integrins to the actin cytoskeleton and signalling pathways. And ILK represents a relevant target for cancer therapy in light of its role in promoting oncogenesis and tumor progression. T315 acts a potent ILK inhibitor, which exhibited high in vitro potency against a panel of prostate and breast cancer cell lines. Here, the anti-tumor effects of T315 were investigated in a panel of oral cancer cells. In this study, the in vitro effects of T315 were evaluated in HSC3, SCC2095, SCC9, and SCC4 cell lines, T315 inhibited cell viability of HSC3, SCC2095, SCC9, and SCC4 cells with IC50 of 1.1, 1.1, 1.2, and 1.2 μM, respectively. T315 induced G2/M arrest by modulating the expression of Cyclin B1 and other cell cycle regulators. Furthermore, T315 upregulated the expression of autophagy related proteins LC3B-II in a dose-dependent manner. Taken together, this data suggest that T315 exerts anti-tumor effects by inducing cell cycle arrest in G2/M phase and autophagy in human oral squamous cell carcinoma.
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33

Huang, Kuo-Yen, and 黃國彥. "Characterization of the Small Compounds -T315 on EGFR Degradation in EGFR-TKI Resistant Lung Adenocarcinoma." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/cw66dg.

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Анотація:
博士
國防醫學院
生命科學研究所
104
ABSTRACT Several nature or synthetic small compounds can be helpful in improving the symptoms of diseases and treating patients. Post-translational modification (PTM) plays a vital role in various biological processes and disease progression such as cellular differentiation, signaling transduction, and protein stability and localization. Aberrant epidermal growth factor receptor (EGFR) signaling is one of the most critical oncogenic pathways in non-small-cell lung carcinoma (NSCLC) that triggers the tumor progression. However, suppression of the EGFR downstream signaling cascade has been considered a main therapeutic approach of intervention for cancer patients. In this thesis, we report that a therapeutically regulatory mechanism utilizing a new small compound T315-mediated EGFR degradation. Exposure to T315 induces apoptosis in lung cancer cell lines, including EGFR wild-type A549 as well as EGFR mutant PC9 and H1975 cells. T315 dose-dependently decreases the EGFR protein level and facilitates dephosphorylation of its downstream targets (AKT and ERK), and both of them play critical roles for lung cancer cell survival. We further demonstrate that T315 induces autophosphorylation at Tyr-1045 in the autophosphorylation domain of EGFR and boosts EGFR degradation through the ubiquitin proteasome pathway by increasing the interaction between the ubiquitin E3 ligase, Casitas B-lineage Lymphoma (CBL), and EGFR. The mass spectrometry implies that T315 may be bound to the extracellular domain of EGFR and subsequent triggers Tyr-1045 autophosphorylation. Finally, the combination of T315 with a commercial tyrosine kinase inhibitor of BIBW2992 additively suppresses in vitro NSCLC cell growth and the mouse xenograft model. Our evidences suggest that T315 is a next-generation of anticancer drug to inhibit the growth of EGFR TKI-resistant lung adenocarcinoma cells via EGFR degradation.
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34

Takahashi, Taro. "Three essays on assessment of foreign aid." Phd thesis, 2004. http://hdl.handle.net/1885/150591.

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35

Abdul, Majeed A'qilah Banu binte. "Effects of multi-site phosphorylation on CaMKII function." Thesis, 2012. http://hdl.handle.net/1959.13/936838.

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Masters Research - Master of Philosophy (Medical Biochemistry)
CaMKII, or calcium/calmodulin stimulated protein kinase II, is a multifunctional Serine/Threonine protein kinase. CaMKII regulates a number of cell processes including synaptic function and plasticity, learning and memory and cell proliferation. CaMKII is ubiquitously expressed and it is crucial to understand how the enzyme is regulated to produce various functional outcomes in the body. CaMKII is regulated in three ways: an increase in intracellular Ca²⁺increases the binding of Ca²⁺/CaM to CaMKII and activates the enzyme, multi-site autophosphorylation and targeting. The activated enzyme can phosphorylate a number of residues on CaMKII itself (autophosphorylation). Phosphorylation of these residues can alter the proteins that CaMKII binds to (targeting). CaMKII can autophosphorylate at several sites such as T253, T286 and T305/306. Phosphorylation of CaMKII at T286 induces autonomous activity (activity in the absence of Ca²⁺/CaM), whereas phosphorylation of CaMKII at T305/306 prevents activation of CaMKII by preventing Ca²⁺/CaM from binding. Phosphorylation of CaMKII at T253 on the contrary has no direct effect on CaMKII activity. Phosphorylation of CaMKII at T253, T286 and T305/306 can change the targeting of CaMKII, and alter the proteins CaMKII binds to. There is evidence that phosphorylation of CaMKII at more than one site can produce different functional outcomes. It is not known how double phosphorylation produces the effects of altered CaMKII function. Therefore, the aim of this project is to investigate if the functional properties of doubly phosphorylated CaMKII will be different from the sum total of the functional properties of the corresponding singly phosphorylated CaMKII. In order to address this aim the functional properties of αCaMKII with phosphomimic mutations at T253, T286 and T305, were compared with αCaMKII containing phosphomimic mutations of two of these sites in various combinations (T253/T286, T286/T305). The comparison was first addressed in vitro by examining the effects of the T253D/T286D, and the T286D/T305D-αCaMKII double phosphomimic mutants compared to the corresponding single phosphomimic mutants on CaM binding, kinase activity and protein binding (targeting). In terms of CaM binding, the results obtained with the double phosphomimic mutants directly reflected the effects of the single phosphomimic mutations. The effects of the T253D/T286D-αCaMKII double phosphomimic mutant on kinase activity reflected that of the combination of the single phosphomimic mutants. In contrast, the effect of the T286D/T305D-αCaMKII double phosphomimic was different to that which would be expected from the sum of the effects of the individual sites. In terms of targeting, both of the double phosphomimics bound a subset of proteins which did not interact with either of the corresponding single phosphomimics. The comparison was then addressed in situ by examining the effects of the T253D/T286D, and T286D/T305D-αCaMKII double phosphomimic mutants on cellular proliferation and cell cycle progression. The effects of expression of the T253D/T286D-αCaMKII, T253D/T305D-αCaMKII and T286D/T305D-αCaMKII double phosphomimic on cellular proliferation/cell cycle were completely different from that of the sum of the effects of its corresponding single phosphomimic mutants. T253D/T286D-αCaMKII expressing cells had a higher proliferation as compared to cells expressing the corresponding individual phosphomimics, T253D-αCaMKII and T286D-αCaMKII. Our results examining CaMKII activity, targeting, and effects on cell cycle progression indicate that phosphorylation of CaMKII at mutiple sites regulate CaMKII function in a co-operative manner.
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36

Talaulikar, Dipti. "The clinical role of ancillary investigations in staging diffuse large B-cell lymphoma." Phd thesis, 2009. http://hdl.handle.net/1885/150942.

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37

Tahiliani, Vikas. "Humoral immunity in secondary poxvirus infection." Phd thesis, 2010. http://hdl.handle.net/1885/151471.

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The studies described in this thesis have utilised the orthopoxvirus ectromelia (ECTV), a natural mouse pathogen that causes a disease termed mousepox, to address the roles of specific innate cell types and T cell subsets in virus control during a secondary infection and more importantly, whether CD4{u207A} T cell help is important for generation of protective recall antibody responses. There are 3 key reasons why the experiments detailed in this thesis were undertaken. First, much of our current understanding of the induction and maintenance of long-lived antibody responses is based on studies using non-replicating model antigens, however, these may not be relevant to replicating viruses. Second, humoral immunity to smallpox (caused by the orthopoxvirus variola), has been reported to be stable and last longer than memory CD4{u207A} or CD8{u207A} T cell responses. Third, recent studies from the ECTV and monkeypox virus models suggest that T cell responses may be redundant but antibody is necessary and sufficient for recovery from a secondary infection. The current thinking in the poxvirus field is that CD4{u207A} T cell help is not required for recall antibody responses for recovery from secondary poxvirus infection. To study the requirements for protection against secondary infection, a prime-challenge regime was used, in which avirulent ECTV (ECTV-TK{u207B}) was used to prime mice that were then challenged with virulent ectromelia virus (ECTV-WT). In mice primed with ECTV-TK{u207B}, the level of virus-neutralizing Ab returned to minimal levels 35 days after priming. Based on this observation it was assumed that the ECTV-TK{u207B} might not be efficient in inducing a B cell memory response. Results presented in Chapter 3 established that mice primed with ECTV-TK{u207B} were able to induce an efficient memory response through the induction of long-lived ECTV - specific ASCs. Neutrophils, plasmacytoid dendritic cells (pDCs), natural killer (NK) cells, T cell subsets and antibody are critical for recovery of mice from primary ECTV infection. Previous studies have shown that recovery of mice from the acute phase of secondary ECTV infection is strictly dependent on antibody responses and does not require CD4{u207A} T cell help or effector functions of CD8{u207A} cytotoxic T lymphocytes. However, neutrophils, pDC and NK cells could contribute to virus control in the absence of T cell subsets. The results presented in Chapter 4 show that the ability of mice individually depleted of neutrophils, pDC and NK cells subsets with specific monoclonal antibodies to overcome a secondary ECTV challenge was not diminished but concurrent depletion of NK cells, pDCs and neutrophils affected virus control and this was clearly evident when one or more T cell subsets were also depleted. Mice depleted of one or both T cell subsets, NK cells, pDCs and neutrophils were unable to control viral load, had a severe reduction in ECTV -specific ASCs and a reduction in the serum neutralising antibody response. Thus, the antibody response alone is not sufficient to mediate protection during the acute phase of secondary ECTV infection. The roles of CD4{u207A} T cell help for antibody production and effector functions of CD8{u207A} T cells over the longer term, past the acute stage of a secondary infection, were canvassed in Chapter 5. Although CD4{u207A} T cell help was apparently not required during the acute phase of a secondary infection, this subset was clearly important in the maintenance of ECTV-specific long-lived ASCs and in the generation of neutralizing antibody as the infection progressed and the response developed. In the continued absence of CD4{u207A} T cells over 35 days post-challenge (achieved by CD4{u207A} T cell depletion), there was a significant increase in the viral load, which correlated with a reduction in ECTV-specific ASCs in the BM, a significant reduction in splenic GC B cells and a significant decrease in levels of virus-neutralizing antibody by D 35 p.c. This was further confirmed using the HEL-specific B cell receptor transgenic system and recombinant viruses that express a mutant version of the antigen, hen-egg lysozyme (HEL) as a viral envelope protein. In spleens of mice depleted of CD4{u207A} T cells, there was a reduction in SW(HEL) GC B cells and a significant decrease in SWHEL GC B cells by D 35 p.c., which SW(HEL) correlated with the reduction in levels of anti-HEL IgG. The effector function of CD8{u207A} T cells becomes critical for virus control in the absence of CD4{u207A} T cells. In the absence of CD4{u207A} T cell help, the effector molecules perforin and possibly granzymes A and B expressed by CD8{u207A} T cells contribute to viral control during the later phases of secondary ECTV infection. Taken together, the results from experiments reported in this thesis provide key findings on the mechanism(s) of protection during a secondary ECTV infection during the acute phase (6-8 days post-challenge), maintenance phase (9-21 days post-challenge) and the long-term maintenance (22-35 days post-challenge). During the acute phase of a secondary ECTV infection, the NK cells, pDCs, neutrophils, T cells and extrafollicular antibodies are important in mediating protection. As the infection progresses, the extrafollicular response continues to be important in mediating protection during the maintenance phase of infection in the absence of CD4{u207A} T cell help. However as the infection further progresses, CD4{u207A} T cell help becomes important for long-term maintenance of antigen-specific memory B cells and long-lived ASCs. Protection mediated during this phase of infection requires CD4{u207A} T cell helper-dependent production of ECTV-specific antibody and also CD8{u207A} T effector cells.
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38

Taube, Richard. "Improving process stability in stamping operations through design of experiments methods." Master's thesis, 1998. http://hdl.handle.net/1885/144505.

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39

Tailby, Nicholas David. "New experimental techniques for studying : (i) trace element substitution in minerals, and (ii) determining S-L-V relationships in silicate-H2O systems at high pressure." Phd thesis, 2009. http://hdl.handle.net/1885/149676.

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Ti site occupancy in zircon (ZrSiO{u2074}) is fundamental to thermobarometry because substitution mechanisms control Ti content-temperature relations. Described here are the results of three independent methods used to demonstrate that Ti predominately substitutes for Si and not Zr in zircon. Zircons were synthesized from oxide powders held in a Na{u2082}WO{u2084} flux at 1 bar and 1,100-1,400 {u00B0}C. Fully buffered experiments run at 1,300 {u00B0}C show zircons equilibrated with rutile + cristobalite have Ti contents (1201 ppm) nearly half that of zircons equilibrated with srilankite + tetragonal zirconia (2640 ppm). The lower Ti content of zircons produced under silica-saturated conditions indicates that Ti substitution predominately occurs on the Si site. Moreover, the higher Ti contents of silica-saturated experiments at 1 bar (1201 ppm), relative to those at 10 kbar (457 ppm, Ferry and Watson, 2007), indicate a substantial pressure effect on Ti solubility in zircon (correcting for different silica species present). Measured Ti K-a edge X-ray Absorption Near Edge Structure (XANES) spectra of synthetic zircons show energies and normalized intensities akin to those seen among tetrahedrally coordinated Ti-bearing standard minerals, strongly suggesting that Ti occupies the Si site. Density functional theory (DFT) calculations confirm that Ti substitution is most likely to occur on the Si site and predict a Ti-O bond length of 1.797 {u00C5} (compared to an average of 2.160 A for substitution on the Zr site), in excellent agreement with X-ray Absorption Fine Structure (EXAFS) spectra of experimentally grown zircons which indicate a value of 1.76(1) {u00C5}. The software FEFF8.4 was used to simulate XANES spectra from the defect structures determined by OFT for Ti substituting on both the Si and Zr sites. The predicted spectrum for Ti on the Si site reproduces all the key features of the experimental zircon spectra, whereas Ti on the Zr site is markedly different. All applied methods confirm that Ti predominately substitutes for Si in zircon. Consequently, the Ti content of zircon is not only a function of temperature, but increases with decreasing silica activity. Because elements that activate or quench cathodoluminescence (CL) in zircon are incorporated into the Zr site, a decoupling of CL signal and Ti distribution (which occurs on the Si site in zircon) is expected. This hypothesis has been verified by a systematic CL-trace element study of natural and experimental zircon.
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40

Take, Reiko. "Autonomy under hegemony in Japanese foreign policy : an irresolvable contradiction?" Phd thesis, 2006. http://hdl.handle.net/1885/146694.

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41

Tang, Kam Ki. "One country, two systems, how many monies? : essays on the exchange rate arrangement of Hong Kong." Phd thesis, 1999. http://hdl.handle.net/1885/147154.

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42

Tahir, Mohammad Iqbal. "Measurement of inflation gains and losses on monetary items : application of stochastic calculus." Phd thesis, 2001. http://hdl.handle.net/1885/148144.

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43

Tan, Kok Piang. "The regolith of the Portia and North Portia prospects, Benagerie Ridge Magnetic Complex, Curnamona, South Australia." Phd thesis, 2001. http://hdl.handle.net/1885/110394.

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This dissertation characterizes the stratigraphic units (sediments and underlying Proterozoic bedrock and its satprolite) across the Portia and North Portia prospects, Situated on the Benagerie Ridge Magnetic Complex (BRMC), bssed on drill core and chip samples. The distribution of mineralization related elements (Cu, Au, Mo, Pb, Zn, and As) in the saprolite and the overlying sediments, their host and secondary minerals, and the factors controlling their distribution (e.g. Eh and pH of the groundwater) have been determined, The nature and origin of gold at the Portia prospect were investigated, and the threshold Au concentrations in the overlying sediments established. Finally, a landscape evolution model at the Portia and North Portia prospects is developed, including weathering and sedimentatiotion chronology, and implications for mineral exploitation are evaluated. The stratigraphic units include the Quaternary sediments, the Tertiary Namba Fornmation (NF) and Portia Unit (PU), and the saprolite of the Proterozoic bedrock. The Quaternary sediments include fluvial sediments, and soils developed in dune sand and present-day floodplain deposits. The sediments are unconsolidated, and range from 2 to 10 m thick. The top l to 2 m are light brown sandy soil with regolith carbonate and groundwater gypsum in the subsoil. Underlying is 3 to 8 m of moderately sorted, fine- to medium-grained olive brown sand and clayey sand. The Namba Formation covers the Benageric Ridge Magnetic Complex, and the thicker Nambu sequence (≈ 50 m) in the north hns been informally named as the upper-, middle-, and lower-Numban Formation (NPU, NFM und NFL respectively) and consists of various grey coloured heavy clays with red and brown mottles. The sand-rich NFU is interpreted as fluvial and flood plain deposits whereas the clay-rich NFM and NFL were deposited In low-energy shallow lucustrine environments. The NF sediments contain threshold element concentrations (up lo 14 ppb Au), except for the NFL sediments at depths greater than 5O m, which accommodate elevated concentrations of chalcophile elements derived from the mineralized saprolite through chemical and physical hydromorphic dispersions. The geochemistry delineates smectite·bearing sediments from kaolinite- and mica- bearing sediments. During diagenesis the NF sediments underwent varying degrees of compaction, pressure and tension from wetting and drying of the smectite-bearing sediments, which resulted in the absence of voids and the presence of masepic fabrics and argillans formed around quartz grains. The Portia Unit comprises light grey c1ay with abundant kaolinite and a varying proportion of mica, and very low in quartz (< 2 %), except at the base of thicker parts which are quartz·rich. Poorly stacked pseudohexagonal kaolinite plates of varying sizes are indicative of a transported origin. Nevertheless, the PU is sourced from proximal saprolite and fills a north-flowing palaeo-channel across the North Portia, Portia and Lorenzo prospects. PU is also present at the Shylock prospect, but is mostly absent or sporadically distributed across the BRMC. The fining upward sequence of the PU results in partitioning of elements into groups that show either upwardlly increasing (Sr, Tl, Te, Cu, Zn, Ni, Ce, La, Pr, Nd, P und S) or downwardly increasing (Zr, Hf, Ti, Sn, Ta, Nb K, Rb, Cs, Au, Y, Se and Si) trends. The bedrock comprises phyllite (carbonaceous) and various albitite lithologies. The major minerals present include carbonate (vein and ellipsoid calcite and dolomite), feldspars (K-feldspar and albite), biotite, chlorite, scapolite, tremolite, pyrite, Fe-oxides, rutile and quartz. XRD analysis shows that the mineral abundances vary significantly within each unit, establishing significant spatial heterogeneity of minerals present. The saprolites developed over the Proterozoic bedrock range from 5 to up to 100 m thick and are dominated by quartz and kaolinite, with varying amounts of goethite and hematite, and mica. The presence of stacks of kaolinite "books" suggests in situ weathering of the saprolite. Zircon and rutile are residually concentrated in highly weathered Al-rich suprolite. Overall, the clement distribution in the saprolite is charecterized by the factors: (As, Pb, V); (Cu, Au, Mo); (Au); (Co. Ni); and (Fe, P). The first three factors represents mineralization in the albitite and phyllite saprolites, whereas (Ni, Co) indicates the presence of pyrite, which is preserved under reducing conditions in the water saturated zone. The fifth group (Fe, Pl represents the presence of ferruginous zones a-nd REEphosphates. Native Cu, covcelite and chalcocite are present in the lower saprolite and remain stable under the weakly reducing and circum-neutral pH conditions of the current groundwater, whereas uraniunite and coffinite are likely to precipitate, as suggested by the positive saturation indices. The surfaces of Au grains with numerous eich pits, dissolution grooves and voids, indicate prolonged dissolution. The presence or galena and altaite fully enclosed within the grains, and the Ag contents similar (<10 %) to those from the Proterozoic bedrock suggest a primary origin for the Au grains. Hence, the Au grains in the saprolite are interpreted as in situ primary Au, whereas those in the PU are placer Au. In comparison, the presence of Ag-depleted rims on the Au grains and small colloidal Au particles (1 μm) are interpreted as secondary Au. The placer Au concentrated at the base of the PU is sourced from the bedrock, preserved in the saprolite, and eroded together with the saprolitic materials and deposited as sediments. Carbonaceous phyllite with abundant quartz, muscovite, and K-feldspar, hosts coarse-grained Au in veins With low sulfide and has the potential to preserve primary Au in the saprolite. Rapid erosion of the saprolite and quick burial by the PU would lower the oxidation potential and preserve the detrotal Au. The curremt reducing and neutral pH groundwater does not favour the formation of chloride, thlosulphate and monohydroxide complexing ligands, but allows the precipitation of Au to form Au colloids, and for detrital and in situ primary Au to remain stable. The BRMC cropped out during the Eocene and weathered under oxidizing conditions to produce a thick and mature saprolite. Subsequently, a period or landscape instability occurred with the incision of the paeleo-channel across the North Portia, Portia and Lorenzo prospects. Sedimentation of the shallow lacustrine Namba Formation followed under reducing conditions and the sedimentary facies changed to f1uvial and flooplain deposits. A change to arid climate in the Quaternary resulted in the formation of dunes, and playa lakes, and the precipitation of groundwter gypsum und regolith carbonate. It
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44

Tan, Michelle. "An analysis of economic problems related to social policy issues in Australia." Phd thesis, 2009. http://hdl.handle.net/1885/150111.

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45

Tanasaldy, Taufiq. "Regional ethnic politics and national political transitions : the Dayaks of West Kalimantan." Phd thesis, 2008. http://hdl.handle.net/1885/110189.

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Анотація:
When the Indonesian New Order regime fell in 1998, regional politics with strong ethnic content resurged across the country. This trend of local politics was enhanced by the promulgation of the Decentralisation Law in 1999 which transferred greater autonomy to the regions. Since the fall of the New Order, West Kalimantan has experienced strong ethnic politics, particularly relating to the Dayaks. Strong Dayak politics in West Kalimantan after the fall of the New Order was not unprecedented. After centuries of occupying a subordinate place in the political and social hierarchy under the nominal rule of the Malay sultanates, Dayaks had begun an enthusiastic political emancipation movement in 1945. It was quite successful and led to the installation of some Dayak elite in the executive council in the provincial and district (kabupaten) governments. Dayaks had an insignificant political role at the provincial level in the early 1950s as a result of their support of the pro-Dutch DIKB. However, when the Partai Dayak, the only Dayak political party, contested the general election in 1955 and the local elections in 1958, it was able to obtain a significant number of votes. Very soon after the election in 1958, four Dayaks were elected as district heads (bupati) and one as governor of the province. The Dayak leadership was replaced after the coming of the New Order because of their association with the leftist Partindo. The Dayaks did not regain their pre-1965 political status until after the regime change in 1998, when Soeharto was forced to resign. This thesis examines the determinants of ethnic politics through an analysis of the case of the Dayaks of West Kalimantan. It asks how and why Dayak politics have experienced drastic changes since 1945. This thesis argues that the oscillations of Dayak politics have been determined largely by events outside the control of Dayak elites, particularly changes in the regime and policies in Jakarta. Some changes restricted Dayak opportunities for political participation, while other changes opened up opportunities. Marginalisation, which has been a strong propeller for ethnic movements elsewhere, has been particularly important in the case of the Dayaks of West Kalimantan. When the opportunities have arisen, the Dayaks have used the issue of marginalisation to pursue their ethnic goals, both in politics and in other sectors. Ethnic identity formation has also determined the course of Dayak politics, particularly during the 1940s and 1950s. Finally, this study finds that the resurgence of Dayak politics after the fall of the New Order was also influenced by the two massive ethnic conflicts in 1997 and 1999. The causes of these and other previous conflicts involving the Madurese were non-political. This thesis finds that historical, cultural, ethnic geographical factors as well as Dayak marginalisation are the most important underlying causes for conflict.
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