Готові списки джерел за темами / Synaptonemal Complex Morphogenesis

Добірка наукової літератури з теми "Synaptonemal Complex Morphogenesis"

Автор: Grafiati
Опубліковано: 10 грудня 2022
Оновлено: 28 січня 2023

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Статті в журналах з теми "Synaptonemal Complex Morphogenesis"

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Espagne, E., C. Vasnier, A. Storlazzi, N. E. Kleckner, P. Silar, D. Zickler, and F. Malagnac. "Sme4 coiled-coil protein mediates synaptonemal complex assembly, recombinosome relocalization, and spindle pole body morphogenesis." Proceedings of the National Academy of Sciences 108, no. 26 (June 10, 2011): 10614–19. http://dx.doi.org/10.1073/pnas.1107272108.

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2

Bailis, J. M., and G. S. Roeder. "Synaptonemal complex morphogenesis and sister-chromatid cohesion require Mek1-dependent phosphorylation of a meiotic chromosomal protein." Genes & Development 12, no. 22 (November 15, 1998): 3551–63. http://dx.doi.org/10.1101/gad.12.22.3551.

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3

Brar, Gloria A., Andreas Hochwagen, Ly-sha S. Ee, and Angelika Amon. "The Multiple Roles of Cohesin in Meiotic Chromosome Morphogenesis and Pairing." Molecular Biology of the Cell 20, no. 3 (February 2009): 1030–47. http://dx.doi.org/10.1091/mbc.e08-06-0637.

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Анотація:
Sister chromatid cohesion, mediated by cohesin complexes, is laid down during DNA replication and is essential for the accurate segregation of chromosomes. Previous studies indicated that, in addition to their cohesion function, cohesins are essential for completion of recombination, pairing, meiotic chromosome axis formation, and assembly of the synaptonemal complex (SC). Using mutants in the cohesin subunit Rec8, in which phosphorylated residues were mutated to alanines, we show that cohesin phosphorylation is not only important for cohesin removal, but that cohesin's meiotic prophase functions are distinct from each other. We find pairing and SC formation to be dependent on Rec8, but independent of the presence of a sister chromatid and hence sister chromatid cohesion. We identified mutations in REC8 that differentially affect Rec8's cohesion, pairing, recombination, chromosome axis and SC assembly function. These findings define Rec8 as a key determinant of meiotic chromosome morphogenesis and a central player in multiple meiotic events.
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4

Sepsi, Adél, James D. Higgins, John S. Pat Heslop-Harrison, and Trude Schwarzacher. "CENH3 morphogenesis reveals dynamic centromere associations during synaptonemal complex formation and the progression through male meiosis in hexaploid wheat." Plant Journal 89, no. 2 (January 2017): 235–49. http://dx.doi.org/10.1111/tpj.13379.

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5

Mytlis, Avishag, Vineet Kumar, Tao Qiu, Rachael Deis, Neta Hart, Karine Levy, Markus Masek, et al. "Control of meiotic chromosomal bouquet and germ cell morphogenesis by the zygotene cilium." Science, May 12, 2022. http://dx.doi.org/10.1126/science.abh3104.

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Анотація:
A hallmark of meiosis is chromosomal pairing, which requires telomere tethering and rotation on the nuclear envelope via microtubules, driving chromosome homology searches. Telomere pulling toward the centrosome forms the “zygotene chromosomal bouquet”. Here, we identified the “zygotene cilium” in oocytes. This cilium provides a cable system for the bouquet machinery, extending throughout the germline cyst. Using zebrafish mutants and live manipulations, we demonstrate that the cilium anchors the centrosome to counterbalance telomere pulling. The cilium is essential for bouquet and synaptonemal complex formation, oogenesis, ovarian development, and fertility. Thus, a cilium represents a conserved player in zebrafish and mouse meiosis, which sheds light on reproductive aspects in ciliopathies, and suggests that cilia can control chromosomal dynamics.
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Osman, Kim, Uthman Algopishi, James D. Higgins, Ian R. Henderson, Keith J. Edwards, F. Chris H. Franklin, and Eugenio Sanchez-Moran. "Distal Bias of Meiotic Crossovers in Hexaploid Bread Wheat Reflects Spatio-Temporal Asymmetry of the Meiotic Program." Frontiers in Plant Science 12 (February 12, 2021). http://dx.doi.org/10.3389/fpls.2021.631323.

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Анотація:
Meiotic recombination generates genetic variation and provides physical links between homologous chromosomes (crossovers) essential for accurate segregation. In cereals the distribution of crossovers, cytologically evident as chiasmata, is biased toward the distal regions of chromosomes. This creates a bottleneck for plant breeders in the development of varieties with improved agronomic traits, as genes situated in the interstitial and centromere proximal regions of chromosomes rarely recombine. Recent advances in wheat genomics and genome engineering combined with well-developed wheat cytogenetics offer new opportunities to manipulate recombination and unlock genetic variation. As a basis for these investigations we have carried out a detailed analysis of meiotic progression in hexaploid wheat (Triticum aestivum) using immunolocalization of chromosome axis, synaptonemal complex and recombination proteins. 5-Bromo-2′-deoxyuridine (BrdU) labeling was used to determine the chronology of key events in relation to DNA replication. Axis morphogenesis, synapsis and recombination initiation were found to be spatio-temporally coordinated, beginning in the gene-dense distal chromosomal regions and later occurring in the interstitial/proximal regions. Moreover, meiotic progression in the distal regions was coordinated with the conserved chromatin cycles that are a feature of meiosis. This mirroring of the chiasma bias was also evident in the distribution of the gene-associated histone marks, H3K4me3 and H3K27me3; the repeat-associated mark, H3K27me1; and H3K9me3. We believe that this study provides a cytogenetic framework for functional studies and ongoing initiatives to manipulate recombination in the wheat genome.
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Дисертації з теми "Synaptonemal Complex Morphogenesis"

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Ahuja, Jasvinder Singh. "A ROLE OF THE PROTEASOME IN RECOMBINATION AND SYNAPTONEMAL COMPLEX MORPHOGENESIS." Cleveland State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=csu1418175456.

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