Добірка наукової літератури з теми "Subclinical organ damage"

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Статті в журналах з теми "Subclinical organ damage"

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Kizer, Jorge R. "Enhancing Detection of Subclinical End-Organ Damage." Circulation 128, no. 10 (September 3, 2013): 1045–47. http://dx.doi.org/10.1161/circulationaha.113.004793.

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Stavropoulos, Konstantinos, Konstantinos P. Imprialos, Michael Doumas, Vasilios G. Athyros, and Asterios Karagiannis. "Subclinical target organ damage in primary aldosteronism." Journal of Hypertension 36, no. 3 (March 2018): 701. http://dx.doi.org/10.1097/hjh.0000000000001642.

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Sehestedt, Thomas, and Michael H. Olsen. "Subclinical organ damage and cardiovascular risk prediction." Blood Pressure 19, no. 3 (January 2010): 132–39. http://dx.doi.org/10.3109/08037051.2010.483054.

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Tornese, F., R. Arsena, G. Geraci, F. Incalcaterra, L. Guarino, G. Cerasola, and S. Cottone. "FETUIN-A AND SUBCLINICAL ORGAN DAMAGE IN RENAL DYSFUNCTION." Journal of Hypertension 29 (June 2011): e55. http://dx.doi.org/10.1097/00004872-201106001-00138.

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Olszanecka, Agnieszka, Aneta Pośnik-Urbańska, Kalina Kawecka-Jaszcz, and Danuta Czarnecka. "Subclinical organ damage in perimenopausal women with essential hypertension." Polish Archives of Internal Medicine 120, no. 10 (October 1, 2010): 390–98. http://dx.doi.org/10.20452/pamw.977.

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Ayub, Ahsan, Hammad Ur Rehman Bhatti, Muhammad Farooq, Aftab Rabbani, and Muhammad Ayyaz. "Subclinical Target Damage of Organ and Creatinine Clearance in Patients with Primary Hypertension." Pakistan Journal of Medical and Health Sciences 16, no. 1 (January 30, 2022): 978–80. http://dx.doi.org/10.53350/pjmhs22161978.

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Background: In spite of the broadly documented risk-factors of uncontrolled hypertension, this ailment is still not cured in most patients. This may be due largely to the symptomless disease nature in the initial 15-20 years, also with progressive damage to the cardio-vascular system. Therefore, the valuation of target damage of organs due to hypertension subclinically is an important procedure for diagnosis of risk-factors stratification in patients with hypertension. The aim of this study is to determine the subclinical target damage of organ among patients with primary hypertension Study Design: A prospective case-control study. Methods: A total of 120 patients were included in this study. Patients with >60 creatinine clearance rate were taken as controls and < 60 creatinine clearance rate as the case group. The 2 groups were made of equal patients 60 in each group. The Cockcroft-Gault formula was applied for determination of renal function and echocardiography was used for valuation of Left ventricular hypertrophy. Direct ophthalmoscopy was done in all patients to assess the retinal vascular changes. Urine microalbumin was evaluated from the morning spot sample. Results: 120 total patients were included in this study. There were 55 males and 65 females. 52.50 ± 8.61 years was the mean age in the control group and in the case group it was 62.20 ± 7.99 years. The incidence of left ventricular hypertrophy with CCR <60 was 23.3% and 48.3% in patients with CCR >60 (p = 0.001). The incidence of microalbuminuria in this analysis was 41.6% in the case group (p = 0.004) and it was 16.7% in the control group. Of the 120 patients in the study, 65 (54.2%) were taking medications for hypertension while 73.3% of the patients in the control group were using drugs for hypertension, the proportion of patients using antihypertensive drugs was 63.7%. Blood pressure was controlled in only 25.8% of the cases taking antihypertensive drugs Conclusions: The obtained outcomes indicate that decreased clearance of creatinine and / or the existence of microalbuminuria is indication of subclinical damage of organ and taken as a marker among individuals with essential hypertension and standard creatinine clearance, independent of BP burden and additional risk factors. Keywords: Target organ damage, primary hypertension, subclinical and creatinine clearance.
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Azevedo, O., F. Ferreira, F. Almeida, C. Ferreira, J. Guardado, M. Fernandes, I. Machado, R. Medeiros, and J. Almeida. "BLOOD PRESSURE VARIABILITY AND SUBCLINICAL TARGET ORGAN DAMAGE: PP.35.472." Journal of Hypertension 28 (June 2010): e590. http://dx.doi.org/10.1097/01.hjh.0000383809.05535.da.

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Gardikioti, V., C. Vlachopoulos, D. Terentes-Printzios, E. Sigala, S. Pantou, N. Ioakeimidis, K. Aznaouridis, P. Mitropoulou, G. Christopoulou, and D. Tousoulis. "ALBUMIN-TO-CREATININE RATIO AND SUBCLINICAL ORGAN DAMAGE IN HYPERTENSIVES." Journal of Hypertension 36, Supplement 1 (June 2018): e271-e272. http://dx.doi.org/10.1097/01.hjh.0000539784.26235.51.

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Handschin, Anja, Stefanie Brighenti-Zogg, Jonas Mundwiler, Stéphanie Giezendanner, Claudia Gregoriano, Benedict Martina, Peter Tschudi, Jörg D. Leuppi, Andreas Zeller, and Thomas Dieterle. "Cardiovascular risk stratification in primary care patients with arterial hypertension: Results from the Swiss Hypertension Cohort Study (HccH)." European Journal of Preventive Cardiology 26, no. 17 (June 12, 2019): 1843–51. http://dx.doi.org/10.1177/2047487319856732.

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Aims Few data are available on cardiovascular risk stratification in primary care patients treated for arterial hypertension. This study aimed at evaluating the cardiovascular risk profile of hypertensive patients included into the Swiss Hypertension Cohort Study according to the 2013 European Society of Hypertension/European Society of Cardiology Guidelines. Methods The Swiss Hypertension Cohort Study is a prospective, observational study conducted by the Centre for Primary Health Care of the University of Basel from 2006 to 2013. Patients with a diagnosis of arterial hypertension (office blood pressure measurement ≥140/90 mmHg) were enrolled. Office blood pressure measurement, cardiovascular risk factors, subclinical organ damage, diabetes mellitus, and established cardiovascular and renal disease were recorded at baseline and at an annual interval during routine consultations by general practitioners in Switzerland. Results In total, 1003 patients were eligible for analysis (55.6% male, mean age: 64.0 ± 13.2 years). At baseline, 78.5% of patients presented with either more than three additional cardiovascular risk factors, diabetes mellitus or subclinical organ damage, while 44.4% of patients had a high or very high overall cardiovascular risk. Cardiovascular risk factors and information about diabetes mellitus, established cardiovascular disease and renal disease were recorded mostly completely, whereas substantial gaps were revealed regarding the assessment of subclinical organ damage. Conclusion The present findings demonstrate that the majority of primary care patients with arterial hypertension bear a substantial number of additional cardiovascular risk factors, subclinical and/or established organ damage. This emphasizes the need for continuous cardiovascular risk stratification and adequate treatment of arterial hypertension in Switzerland.
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Linde, Anja, Eva Gerdts, Kåre Steinar Tveit, Ester Kringeland, and Helga Midtbø. "Subclinical Cardiac Organ Damage in Patients with Moderate to Severe Psoriasis." Journal of Clinical Medicine 10, no. 11 (May 31, 2021): 2440. http://dx.doi.org/10.3390/jcm10112440.

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We explored the association between subclinical cardiac organ damage (OD) with comorbidities and psoriasis severity in 53 psoriasis patients on infliximab treatment (age 47 ± 15 years, 30% women) and 99 controls without psoriasis (age 47 ± 11 years, 28% women). Cardiac OD was assessed by echocardiography as the presence of increased left ventricular (LV) relative wall thickness (RWT), LV hypertrophy or dilated left atrium. Psoriasis severity was graded using the psoriasis area and severity index (PASI). The prevalence of hypertension was 66% in psoriasis vs. 61% in controls (p = 0.54) and cardiac OD seen in 51 and 73%, respectively (p = 0.007). Psoriasis was associated with a lower prevalence of cardiac OD (odds ratio (OR) 0.32, 95% confidence interval (CI) 0.13–0.77, p = 0.01) independent of age, sex, smoking, body mass index, and hypertension. Among psoriasis patients, hypertension was associated with increased risk of subclinical cardiac OD (OR 6.88, 95% CI 1.32–35.98, p = 0.02) independent of age, sex, and body mass index. PASI at treatment initiation was associated with a higher RWT at follow-up, independent of sex, age, and hypertension (β 0.36, p = 0.006) while no association with current PASI was found. In conclusion, cardiac OD was less prevalent in psoriasis patients on infliximab treatment than controls. Hypertension was the major covariable for subclinical cardiac OD in psoriasis.
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Дисертації з теми "Subclinical organ damage"

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Tagetti, Angela. "EARLY PREDICTION OF SUBCLINICAL VASCULAR DAMAGE IN RISKY POPULATIONS." Doctoral thesis, 2022. http://hdl.handle.net/11562/1062695.

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Background. Atherosclerosis is a progressive disease that starts during adoles-cence and exerts its negative effects later in life. High blood pressure is one of the principal risk factors for cardiovascular disease. Central blood pressure is the pressure that directly insists and other major arteries and is linked to target organ damage and cardiovascular events. The aim of the thesis was to assess the role of traditional and novel risk factors (central blood pressure, cBP) on children and adolescents with type I diabetes (T1D; study number 1) and in children and ado-lescents with solitary functional kidney (SFK; study n.2). Methods. Carotid intima-media thickness (cIMT), carotid distensibility coeffi-cient (cDC), and carotid-femoral pulse wave velocity (PWV), were measured in children and adolescents with T1D and SFK. Blood Pressure (BP; both central and peripheral), echocardiographic measurements, biochemical data from blood and urine sample and other cardiovascular risk factors were evaluated in multi-variate linear regressions to assess the association with the measured indices of subclinical vascular damage. Results study 1. One hundred and twenty-six children and adolescents with T1D were included. cIMT was above the 95th percentile for age and height in 61% of the population. Bivariate correlations showed that cBP but not peripheral blood pressure (pBP) were positively associated with cIMT (r = 0.285; p = 0.001). In-dependent determinants of cIMT according to the regression models were only gender, type of glucose monitoring and central systolic BP (cSBP). PWV was as-sociated with age, sex, heart rate, and cSBP; cDC with age and both cSBP, and, alternatively, peripheral BP (pBP). Neither pBP nor any of the tested metabolic parameters, including glycated hemoglobin, were associated with PWV and cIMT. Results study 2. 48 SFK children and adolescents were included. Of them 50% had increased cIMT. cBP was correlated with all vascular indices measured and with the left ventricular mass (r = 0.417; p = 0.005) but not with RWT. pBP cor-related with distensibility, with PWV and with the LVMi. Daytime systolic blood pressure was found to be associated with all vascular indices but not with echo-cardiographic ones. BMI correlated with the variables indicative of organ dam-age and with many pressure variables. No correlation was found between the vas-cular or echocardiographic indices and either estimated glomerulaf filtration rate or urinary albumin to creatinine ratio. In linear regression pBP were not associat-ed with the above-mentioned vascular variables whereas cBP was positively as-sociated with cIMT (even when we consider z-score values). To the contrary, cDC and PWV were not associated with cBP. In binary logistic regression analy-sis, cBP was a predictor for increased cIMT. Conclusions: Taken together, our data show a high prevalence of increased cIMT in children and adolescents with T1D and SFK. cBP more than pBP or other tra-ditional risk factors associates with subclinical organ damage.
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Книги з теми "Subclinical organ damage"

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Vannuzzo, Diego, and Simona Giampaoli. Primary prevention: principles and practice. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656653.003.0007.

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Cardiovascular primary prevention is a coordinated set of actions at community and individual level aimed at eradicating, eliminating, or compressing at later ages the impact of cardiovascular diseases and their related disability. Its aim is healthy ageing. Cardiovascular epidemiology has elucidated the role of cardiovascular risk factors, forming the basis of strategies to reduce cardiovascular risk and subsequent disease. There is evidence that cardiovascular primary prevention works if three strategies are implemented together: a population strategy (particularly through a widespread adoption of healthy lifestyles) which aims to keep everyone at low risk from infancy and reduces the cardiovascular risk profile of the whole community; an individualized high-risk strategy through lifestyle changes also prophylactic evidence-based drugs if necessary; and an individualized intermediate-risk strategy which may benefit from non-invasive assessment of subclinical disease and end organ damage.
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Vannuzzo, Diego, and Simona Giampaoli. Primary prevention: principles and practice. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199656653.003.0007_update_001.

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Анотація:
Cardiovascular primary prevention is a coordinated set of actions at community and individual level aimed at eradicating, eliminating, or compressing at later ages the impact of cardiovascular diseases and their related disability. Its aim is healthy ageing. Cardiovascular epidemiology has elucidated the role of cardiovascular risk factors, forming the basis of strategies to reduce cardiovascular risk and subsequent disease. There is evidence that cardiovascular primary prevention works if three strategies are implemented together: a population strategy (particularly through a widespread adoption of healthy lifestyles) which aims to keep everyone at low risk from infancy and reduces the cardiovascular risk profile of the whole community; an individualized high-risk strategy through lifestyle changes also prophylactic evidence-based drugs if necessary; and an individualized intermediate-risk strategy which may benefit from non-invasive assessment of subclinical disease and end organ damage.
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Частини книг з теми "Subclinical organ damage"

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Mancia, Giuseppe, and Stéphane Laurent. "Assessment of subclinical organ damage for stratification of total cardiovascular risk." In Reappraisal of European guidelines on hypertension management: A European Society of Hypertension Task Force document, 5–18. Tarporley: Springer Healthcare Ltd., 2011. http://dx.doi.org/10.1007/978-1-907673-40-5_2.

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Erbel, Raimund, Nils Lehmann, Andreas Stang, Sofia Churzidse, Susanne Moebus, and Karl-Heinz Jöckel. "Blood Pressure and Atherosclerosis: Subclinical Arteriosclerosis as an Early Sign of Organ Damage." In Updates in Hypertension and Cardiovascular Protection, 363–81. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-75310-2_26.

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Cífková, Renata. "Assessment of Total Cardiovascular Risk in Hypertension: The Role of Subclinical Organ Damage." In Special Issues in Hypertension, 199–211. Milano: Springer Milan, 2012. http://dx.doi.org/10.1007/978-88-470-2601-8_16.

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Novo, J., A. Hermida, M. Ortega, N. Barreira, M. G. Penedo, J. E. López, and C. Calvo. "“White Coat” Effect Study as a Subclinical Target Organ Damage by Means of a Web Platform." In Innovation in Medicine and Healthcare 2016, 279–87. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-39687-3_27.

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Gonzlez-Quevedo, Alina, Sergio Gonzlez, Otman Fernndez, Rosaralis Santiesteban, Luis Quevedo, Marisol Pea, Rebeca Fernndez, and Zenaida Hernndez. "Demonstration of Subclinical Organ Damage to the Central Nervous System in Essential Hypertension." In Brain Damage - Bridging Between Basic Research and Clinics. InTech, 2012. http://dx.doi.org/10.5772/38494.

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