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1

Bunea, Marina, Radu Bosoanca, Adrian Cojan, and Iulian Gabriel Birsan. "Thermomechanical and Electrical Properties of Fabric Reinforced Laminates with Filled Stratified Epoxy Matrix." Materiale Plastice 55, no. 3 (September 30, 2018): 269–73. http://dx.doi.org/10.37358/mp.18.3.5011.

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Анотація:
The thermal coefficient of linear expansion, the electrical conductivity and dielectric permittivity of fabric reinforced hybrid composites with filled stratified epoxy matrix were investigated. The measurements of electrical conductivity and dielectric permittivity had been performed, using standard method regarding electrical resistance and electrical capacity. In order to point out the effect of filler and of the spatial distribution of reinforcement layers, the medial layer of fabric was especially prepared by introducing copper wires in the woven. So, the medial layer is made of different types of tows (carbon, aramid, glass). This attempt is made in order to design a composite able to provide information about its state during various loading. The results showed that the fillers did not improve the electrical parameters of epoxy matrix, but they led to reduce the thermal coefficient of linear expansion. The thermal and electrical behavior of hybrid composites varied in dependence of number of carbon layers and fiber orientation.
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2

Stefanescu, Victorita, Ana Boboc, A. Cojan, R. Bosoanca, cristian Muntenita, and Marina Bunea. "The Thermal Behavior of Hybrid Fabric Reinforced Composites with Stratified Filled Epoxy Matrix." Materiale Plastice 55, no. 2 (June 30, 2018): 161–67. http://dx.doi.org/10.37358/mp.18.2.4986.

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Анотація:
In this research, the thermal performance of the hybrid composites with modified epoxy matrix was investigated. The results were compared with those presented by the hybrid composites with homogeneous epoxy matrix. For understand the effects of the replacement of lower specific density glass fabric by higher specific density glass fabric, the thermal properties of the hybrid epoxy composites were determined by comparison to the thermal results of composites reinforced with lower specific density glass fabric with those of the hybrid epoxy materials reinforced with higher specific density glass fabric. Also, the effects on the specific heat and thermal expansion coefficient of the used fabric types in outer sheets of the composites were studied.
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3

Birsan, Iulian Gabriel, Vasile Bria, Marina Bunea, and Adrian Circiumaru. "An Experimental Investigation of Thermal Properties of Fabric Reinforced Epoxy Composites." Materiale Plastice 57, no. 2 (July 1, 2019): 159–68. http://dx.doi.org/10.37358/mp.20.2.5362.

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Specific heat and thermal linear expansion coefficient of epoxy composites reinforced with carbon, aramid, glass and hybrid fabrics with unfilled and filled stratified matrices were studied. The thermal measurements of specific heat were performed with Differential Scanning Calorimeter (DSC instrument) and those of thermal coefficient of linear expansion were realized with Thermomechanical Analyzer (TMA instrument). It was analyzed the influence of fiber orientation at various angles (�15�, �30� and �45�) and the effects of two types of filler mixtures added into polymeric matrix on the thermal behavior of composite materials. It was found that in case of epoxy matrix the added filler mixtures reduced its thermal coefficient of linear expansion and had an insignificant influence on specific heat. In case of epoxy composites reinforced with fabrics, the fiber orientation and fillers addition showed different effects on the investigated thermal parameters in dependence of the used reinforcement types.
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4

Bunea, Marina, Iulian Gabriel Birsan, and Adrian Circiumaru. "An Experimental Study on the Low Velocity Impact Behavior of Hybrid Epoxy Composites." Materiale Plastice 57, no. 2 (July 1, 2019): 179–90. http://dx.doi.org/10.37358/mp.20.2.5364.

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Анотація:
The low velocity impact response of hybrid epoxy composites reinforced with plain weave fabrics, ply orientation at various angles and filled stratified matrix was analyzed in this study. The hybrid epoxy composites were subjected to impact tests at 45J and 90J of energy levels with drop weight impact machine. The damaged areas were investigated by visual inspection of impacted and non-impacted surfaces and by tomographic images. It was found that the replacement of certain carbon inner plies with glass ones and the modification of fiber orientation improved the damage resistance of the hybrid composites with aramid outer layers subjected to impact loading at 45J of energy level.
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5

Szymańska, Jowita, Mohamed Bakar, Anita Białkowska, and Marcin Kostrzewa. "Study on the adhesive properties of reactive liquid rubber toughened epoxy-clay hybrid nanocomposites." Journal of Polymer Engineering 38, no. 3 (March 28, 2018): 231–38. http://dx.doi.org/10.1515/polyeng-2017-0099.

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AbstractThe present work investigates the adhesive properties and morphology of diglycidyl ether of bisphenol A nanocomposites modified with reactive butadiene acrylonitrile copolymers having different amine equivalent weight. Tensile adhesive strength and shear adhesive strength of epoxy resin were significantly increased due to reactive rubbers and nanoparticles (ZW1) incorporation to the epoxy matrix. Hybrid composites based on 1 wt% ZW1 and 10 wt% ATBN-16, 1 wt% ZW1 and 15 wt% ATBN-21 exhibited maximum adhesive strength in comparison with neat epoxy resin as well as epoxy nanocomposite containing 1% ZW1. Tensile adhesive strength of hybrid composites containing 1% ZW1 and 10% ATBN-16 as well as 1% ZW1 and 15% ATBN-21 was maximally enhanced. The fracture surfaces of epoxy hybrid composites showed significant plastic yielding together with delaminated and stratified structures, explaining thus the increase of the adhesive strength of tested composites. This finding was confirmed by FTIR spectra in terms of chemical reactions occurrence between the reactive rubbers and epoxy matrix.
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6

Bunea, M., A. Cîrciumaru, M. Buciumeanu, I. G. Bîrsan, and F. S. Silva. "Low velocity impact response of fabric reinforced hybrid composites with stratified filled epoxy matrix." Composites Science and Technology 169 (January 2019): 242–48. http://dx.doi.org/10.1016/j.compscitech.2018.11.024.

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7

Szymańska, Jowita, Mohamed Bakar, Marcin Kostrzewa, and Marino Lavorgna. "Preparation and characterization of reactive liquid rubbers toughened epoxy-clay hybrid nanocomposites." Journal of Polymer Engineering 36, no. 1 (January 1, 2016): 43–52. http://dx.doi.org/10.1515/polyeng-2014-0393.

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Анотація:
Abstract The present work investigates the effect of organomodified nanoclay (ZW1) and butadiene-acrylonitrile copolymer terminated with different amine groups (amine-terminated butadiene-acrylonitrile, ATBN) on the properties and morphology of epoxy resin. The morphologies of the nanocomposites were analyzed by X-ray diffraction (XRD) analysis, transmission electron microscopy (TEM) and scanning electron microscopy (SEM). The nanocomposites structure was confirmed by Fourier transform infrared (FTIR) spectroscopy, XRD and TEM. The properties evaluation showed that the polymeric modifier and nanoclays strongly influence the fracture toughness and flexural properties of the nanocomposites. Hybrid epoxy composites containing 1% ZW1 and ATBN rubbers showed improved fracture toughness and flexural properties in comparison with unmodified epoxy resin. FTIR spectra showed an increase in the hydroxyl peak height peak height of 3360 cm-1 due to reactive rubber incorporation. SEM micrographs of hybrid epoxy resin nanocomposites showed significant plastic yielding of the polymer matrix with stratified structures and more cavitations, explaining thus the enhancement of fracture toughness and flexural strength of the nanocomposites.
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8

Jyani, Gaurav, Shankar Prinja, Sitanshu Sekhar Kar, Mayur Trivedi, Binod Patro, Fredrick Purba, Star Pala, et al. "Valuing health-related quality of life among the Indian population: a protocol for the Development of an EQ-5D Value set for India using an Extended design (DEVINE) Study." BMJ Open 10, no. 11 (November 2020): e039517. http://dx.doi.org/10.1136/bmjopen-2020-039517.

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IntroductionQuality-adjusted life year (QALY) has been recommended by the government as preferred outcome measure for Health Technology Assessment (HTA) in India. As country-specific health-related quality of life tariff values are essential for accurate measurement of QALYs, the government of India has commissioned the present study. The aim of this paper is to describe the methods for the Development of an EQ-5D Value set for India using an Extended design (DEVINE) Study. Additionally, this study aspires to establish if the design of 10-time trade-off (TTO) blocks is enough to generate valid value sets.Methods and analysisA cross-sectional survey using the EuroQol Group’s Valuation Technology (EQ-VT) will be undertaken in a sample of 2700 respondents selected from six different states of India using a multistage stratified random sampling technique. The participants will be interviewed using computer-assisted personal interviewing technique. The TTO valuation will be done using 10 composite TTO (c-TTO) tasks and 7 discrete choice experiment (DCE) tasks. Hybrid modelling approach using both c-TTO and DCE data to estimate the potential value set will be applied. Values of all 3125 health states will be predicted using both the conventional EQ-VT design of 10 blocks of 10 TTO tasks, and an extended design of 18 blocks of 10 TTO tasks. The potential added value of the eight additional blocks in overall validity will be tested. The study will deliver value set for India and assess the adequacy of existing 10-blocks design to be able to correctly predict the values of all 3125 health states.Ethics and disseminationThe ethical approval has been obtained from Institutional Ethics Committee of PGIMER, Chandigarh, India. The anonymised EQ-5D-5L value set will be available for general use and in the HTAs commissioned by India’s central HTA Agency.
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9

Perez Beltran, Saul, and Perla B. Balbuena. "Lithium Dissolution and SEI Formation on Lithium Metal Anodes: Electrolyte and Surface Effects." ECS Meeting Abstracts MA2022-02, no. 2 (October 9, 2022): 145. http://dx.doi.org/10.1149/ma2022-022145mtgabs.

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The lithium metal battery (LMB) rises as one of the most promising energy storage alternatives primarily due to the lithium metal’s high theoretical specific capacity (3860 mAh/g vs. 372 mAh/g for graphite) and high achievable operation voltage [1, 2]. However, and regardless of the coupling cathode electrode, one of the main challenges before the practical application of LMBs comes down to engineering electrolyte formulations compatible with lithium metal to eliminate dendrite formation and the uncontrolled loss of electrolyte and active lithium by forming a robust, ionic-conductive, and electron insulating, solid electrolyte interphase (SEI). Any improvement of the electrolyte/lithium metal interface passes through a thorough understanding of the reaction mechanisms behind the electrolyte degradation and the subsequence formation of the SEI. Characterizing this interface via experimental techniques is a challenge because of its delicate nature and simultaneous presence of liquid and solid phases. Here, we successfully narrowed this gap via computational modeling by using a recently introduced hybrid ab initio and reactive molecular dynamics (HAIR) scheme that uses in sequence the ab-initio molecular dynamics (AIMD) and the reactive force field (ReaxFF) methods to extend the time window achievable with the AIMD method alone. We performed a series of HAIR calculations with multiple electrolytes formulations on a lithium metal slab (Li(100)) with varying electrolyte/anode (E/A) ratios to evaluate the impact of the lithium salt concentration, type of solvent, presence of a diluent, and lithium thickness on the rate of electrolyte depletion, lithium dissolution, and SEI morphology. It is found that increasing salt concentration in a LiFSI/DMC electrolyte from 1 to 5 and then to 10 M yields significant changes in SEI morphology. The 1 M electrolyte led to DMC degradation into -O-CH3 with no significant LiO formation. In contrast, the 5 and 10 M formulations evolved into an SEI structure dominated by continuous and stratified LiO and LiF phases. Changes in the SEI morphology based on the E/A ratio for the 10 M LiFSI/DMC electrolyte revealed the existence of an intermediate E/A ratio leading to a more compact and more inorganic-rich SEI; the formed LiO phase density was higher than that in other ensembles representative of dry and flooded electrolyte operation conditions. Our third set of calculations focused on the effect of solvent chemistry. The 5 M LiFSI/DME electrolyte led to the formation of a LiO phase surrounded by some residual DME solvent; in this wetted SEI, the residual solvent provides diffusion channels for Li+ ions. Finally, we tested the impact of adding 1,1,2,2-tetrafluoroethylene 2,2,3,3-tetrafluoropropyl ether (TTE) as a diluent into the electrolyte using a 1.3 M LIFSI:DMC:TTE (1:1.2:3 molar ratio) formulation. The TTE diluent showed decomposition and helped grow a LiF-dominated SEI film with a lower LiO/LiF phase ratio than the equivalent 5.0 M LiFSI/DMC formulation with no electrolyte. These results form the basis for a deeper understanding of the SEI formation mechanisms and provide a design guideline for SEI films based on the lithium salt concentration, relative electrolyte/electrode content, and presence of a diluent. References: 1. Asenbauer, J., et al., The Success Story of Graphite as a Lithium-Ion Anode Material – Fundamentals, Remaining Challenges, and Recent Developments Including Silicon (Oxide) Composites. Sustainable Energy & Fuels, 2020. 4(11): p. 5387-5416. 2. Liu, B., J.-G. Zhang, and W. Xu, Advancing Lithium Metal Batteries. Joule, 2018. 2(5): p. 833-845.
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10

Birk, Manjot, Vivien Chan, Nicholas J. Yee, Evan Dimentberg, Jessica Wenghofer, Matias Pereira Duarte, Tara Gholamian, et al. "Canadian Spine SocietyCPSS-1. Abstract ID 108. Radiographic reporting in adolescent idiopathic scoliosis: Is there a discrepancy between radiologists’ reports and surgeons’ assessments?CPSS-2. Abstract ID 21. Pediatric posterior spinal deformity correction: 30-day postoperative infection rate and risk factorsCPSS-3. Abstract ID 17. “Ultra-low dose” computed tomography without sedation is feasible and should be considered as part of the preoperative optimization pathway in paediatric patients with neuromuscular scoliosisCPSS-4. Abstract ID 20. SeeSpine: a novel surface topography smartphone application for monitoring curve progression in adolescent idiopathic scoliosisCPSS-5. Abstract ID 78. Pilot study: a machine learning algorithm for the detection of adolescent idiopathic scoliosis from images taken with modern smartphone technologyCPSS-6. Abstract ID 101. Preoperative parameters influencing vertebral body tethering outcomes: patient characteristics play an important role in determining the outcomes at 2 years after surgeryCPSS-7. Abstract ID 63. Preoperative bending radiographs are the best predictor of scoliosis correction on the first erect radiograph in vertebral body tethering: a single-centre retrospective studyCPSS-8. Abstract ID 18. Adverse events after zoledronate infusion in medically complex patients with neuromuscular scoliosisCPSS-9. Abstract ID 5. Sequential rod rolling for surgical correction of Lenke type 2 adolescent idiopathic scoliosis: a 3D analysisCPSS-10. Abstract ID 123. A comparative study of protocols for spinal casting as a surgical delay strategy in severe early-onset scoliosisA-11. Abstract ID 50. Does the type of pelvic fixation affect pelvic incidence after adult spinal deformity surgery? A retrospective analysisA-12. Abstract ID 51. How does pelvic fixation affect the compensatory mechanisms after adult spinal deformity surgery? A retrospective analysisA-13. Abstract ID 44. Development of a biomechanical model to identify risk factors in sagittal alignment contributing to proximal junctional kyphosisA-14. Abstract ID 32. Biomechanical characterization of semirigid constructs and the potential effect on proximal junctional kyphosisA-15. Abstract ID 65. Early adjacent disc characteristics are not associated with reoperation in short-segment lumbar fusionsA-16. Abstract ID 39. Concurrent validation of a novel inertial measurement unit–based method to evaluate spinal motion in clinical settingsA-17. Abstract ID 68. Distal lordosis is associated with reoperation for adjacent segment disease in patients with degenerative lumbar fusionA-18. Abstract ID 69. Automatic extraction of spinopelvic parameters using artificial intelligence methods and a review on the effects of spine stiffness, spinal fusion and spinopelvic parameters on lower limb motion and total hip arthroplasty outcomesA-19. Abstract ID 38. Gender differences in fusion rates in the treatment of degenerative lumbar spondylolisthesis: analysis from the CSORN prospective degenerative lumbar spondylolisthesis studyA-20. Abstract ID 29. L3–4 hyperlordosis after a reduction in lower lumbar lordosis with L4–L5 fusion surgery is common in patients requiring L3–4 revision surgery for adjacent segment diseaseB-21. Abstract ID 40. Predictors of dynamic instability in the decision to fuse in degenerative lumbar spondylolisthesis: results from the Canadian Spine Outcomes and Research Network prospective degenerative lumbar spondylolisthesisstudyB-22. Abstract ID 49. Impact of preoperative insomnia on poor postoperative pain control after elective spine surgery and the Modified Calgary Postoperative Pain After Spine Surgery scoreB-23. Abstract ID 115. Influence of high pelvic incidence on operative difficulty in patients treated surgically for degenerative lumbar spondylolisthesisB-24. Abstract ID 45. Reoperation rates for adjacent segment disease in degenerative lumbar fusion surgery: a comparison between minimally invasive versus open surgical approachesB-25. Abstract ID 118. Assessment of changes in opioid utilization 1 year after elective spine surgery: a Canadian Spine Outcomes and Research Network studyB-26. Abstract ID 93. Preoperative neuroleptic and opioid use effects on postoperative pain and disability after spinal surgery for lumbar radiculopathyB-27. Abstract ID 52. The importance of lower extremity compensation mechanisms in lumbar degenerative pathology: a retrospective analysisB-28. Abstract ID 107. Persistent poor sleep is associated with worse pain and quality of life in patients with degenerative thoracolumbar conditions undergoing surgery: a retrospective cohort studyB-29. Abstract ID 126. Opioid use in low back pain is associated with increased utilization of health care services and likelihood of work absenteeismB-30. Abstract ID 53. Wait times for degenerative lumbar spine consultation and surgery: a repeated cross-sectional analysis of the Canadian Spine Outcomes and Research NetworkC-31. Abstract ID 33. Patients with radicular pain improve more than those with axial pain alone after treatment for metastatic spine diseaseC-32. Abstract ID 46. Association between nutritional status and survival in patients requiring treatment for spinal metastasesC-33. Abstract ID 47. Introduction of the new Patient Expectations in Spinal Oncology questionnaireC-34. Abstract ID 74. Medium-term follow-up outcomes in palliative transpedicular corpectomy with cement-based anterior vertebral reconstruction performed for patients with spinal metastasisC-35. Abstract ID 10. Perception of frailty in spinal metastatic disease: international survey of the AO Spine CommunityC-36. Abstract ID 73. COVID-19: Were we able to get back to the prepandemic level of spine surgery activity? An experience from a tertiary referral centre in QuebecC-37. Abstract ID 114. Provider confidence with virtual spine exams 2 years after COVID-19 lockdown restrictionsC-38. Abstract ID 76. The impact of nasal decontamination by photodisinfection in spine surgery: a feasibility pilot studyC-39. Abstract ID 116. Exploring the bacterial hypothesis of low back pain: a prospective cohort studyC-40. Abstract ID 7. Management of deep surgical site infections of the spine: a Canadian surveyD-41. Abstract ID 26. Earlier tracheostomy reduces complications in complete cervical spinal cord injury in real-world practice: analysis of a multicentre cohort of 2001 patientsD-42. Abstract ID 87. Neuroprotection after traumatic spinal cord injury through mitochondrial calcium uniporter inhibitionD-43. Abstract ID 16. The impact of specialized versus nonspecialized acute hospital care on survival among patients with acute incomplete traumatic spinal cord injuries: a population-based observational study from British Columbia, CanadaD-44. Abstract ID 59. Stem cells from human spinal cord exhibit reduced oligodendrogenesis compared with rodent stem cellsD-45. Abstract ID 122. Harnessing the endogenous stem cell response after spinal cord injuryD-46. Abstract ID 62. Comparison of age and 5-Item Modified Frailty Index as predictors of in-hospital mortality for patients with complete traumatic cervical spinal cord injuryD-47. Abstract ID 109. Unplanned readmissions after traumatic spinal cord injury: perspective from the British Columbian populationD-48. Abstract ID 9. The radiographic characteristics that lead surgeons to agree and disagree on making treatment recommendations in thoracolumbar burst fractures without neurologic deficitsD-49. Abstract ID 19. The effect of Enhanced Recovery After Surgery protocols for elective cervical and lumbar spine procedures on hospital length of stay: a systematic review and meta-analysisD-50. Abstract ID 23. Exploring end-of-life decision-making and perspectives on medical assistance in dying through the eyes of individuals living with cervical spinal cord injuries in Nova ScotiaE-51. Abstract ID 88. Neurologically intact thoracolumbar burst fractures (AO Spine A3, A4) improve on Oswestry Disability Index equally when treated surgically versus nonoperativelyE-52. Abstract ID 28. Predictive algorithm for surgery recommendation in thoracolumbar burst fractures without neurological deficitsE-53. Abstract ID 36. A randomized trial of cervical orthosis versus no orthosis after multilevel posterior cervical fusionE-54. Abstract ID 11. Deterioration after surgery for degenerative cervical myelopathy: an observational study from the Canadian Spine Outcomes and Research NetworkE-55. Abstract ID 66. Canadian cohort of older patients with cervical spinal cord injury: Do radiologic parameters correlate with initial neurological impairment?E-56. Abstract ID 6. Surgical complications or neurologic decline? A patient discrete-choice experiment for cervical myelopathyE-57. Abstract ID 82. Laminectomy alone for cervical spondylotic myelopathy: a Canadian Spine Outcomes and Research Network StudyE-58. Abstract ID 95. The effect of surgical approach on patient outcomes of degenerative cervical myelopathy: a pooled analysis of individual patient data from 1031 casesE-59. Abstract ID 81. Occiput and upper cervical fusions: Does navigation matter? A Canadian Spine Outcomes and Research Network studyE-60. Abstract ID 89. Preoperative therapies improve postoperative disability in patients who undergo anterior cervical discectomy and fusion surgery for cervical radiculopathyF-61. Abstract ID 58. The influence of wait time on surgical outcomes in elective lumbar degenerative surgery: a Canadian Spine Outcomes and Research Network studyF-62. Abstract ID 77. A cost consequence analysis comparing spinal fusion versus decompression alone for lumbar degenerative spondylolisthesisF-63. Abstract ID 96. Economic impact of wait time in degenerative lumbar stenosis surgery: association with time away from work, chronic persistent opioid use and patient satisfactionF-64. Abstract ID 121. Optimal timing of surgery for symptomatic single-level lumbar disc herniation: a cost-effectiveness analysisF-65. Abstract ID 67. Impact of scheduled spine surgery for degenerative spinal disorders on patient health-related quality of life compared with the general Canadian populationF-66. Abstract ID 84. Decompression and decompression and fusion and the influence of spinopelvic alignment in the outcome of patients with degenerative lumbar spondylolisthesisF-67. Abstract ID 43. Association between poor postoperative pain control and surgical outcomes after elective spine surgeryF-68. Abstract ID 56. Factors associated with shorter wait times for lumbar degenerative spinal surgeryF-69. Abstract ID 25. Is navigation a game changer in single-level transforaminal lumbar interbody fusions?F-70. Abstract ID 34. Radiologic and clinical evaluation of posterolateral versus interbody fusion in degenerative lumbar spondylolisthesisG-71. Abstract ID 15. Timing of recovery after surgery for patients with degenerative cervical myelopathy: an observational study from the Canadian Spine Outcomes and Research NetworkG-72. Abstract ID 30. Development of a patient-centred cervical myelopathy severity index: measurement property testing, item generation and item reductionG-73. Abstract ID 75. The preoperative expectations of patients with degenerative cervical myelopathyG-74. Abstract ID 61. Satisfaction with surgical treatment for degenerative cervical myelopathy is driven by improvement in patient-reported outcomesG-75. Abstract ID 98. Identification of surgical candidates for mild degenerative cervical myelopathy: a trajectory-based analysisG-76. Abstract ID 100. The impact of surgery on pain in degenerative cervical myelopathy: a pooled analysis of 1047 patients from CSM-North America, CSM-International and CSM-Protect trialsG-77. Abstract ID 104. National adverse event rates after cervical spine surgery for degenerative disorders, and impact on patient satisfactionG-78. Abstract ID 8. The unsustainable growth of out-of-hours emergent surgery for degenerative spinal disease in Canada: a retrospective cohort study from a national registryG-79. Abstract ID 102. Effect of compensation claim status on perioperative outcomes in patients with degenerative spine conditionsG-80. Abstract ID 13. Outcomes of spinal cord stimulation for management of neuropathic pain in patients with spinal cord injuryP-81. Abstract ID 97. Meaningfulness in clinical improvements at 12 months after surgery for degenerative cervical myelopathy: comparison of 30% change versus absolute change values of minimal clinically important differenceP-82. Abstract ID 22. An exploration of the evolving perception of quality of life from the perspective of individuals living with a cervical spinal cord injury in Nova ScotiaP-83. Abstract ID 41. Delays in diagnosis of degenerative cervical myelopathy: a population-based study using the Clinical Practice Research DatalinkP-84. Abstract ID 119. Sex, drugs and spine surgery: a nationwide analysis of opioid utilization and patient-reported outcomes in males and femalesP-85. Abstract ID 117. The feasibility of a multidisciplinary transitional pain service in patients undergoing spine surgery to minimize opioid use and improve perioperative outcomes: a quality improvement studyP-86. Abstract ID 103. Predictors of poor postoperative patient satisfaction in patients undergoing elective spine surgery with pre-existing compensation claimsP-87. Abstract ID 60. The efficacy and safety of P-15 peptide enhanced bone graft in bone regeneration: a systematic reviewP-88. Abstract ID 113. The influence of preoperative back pain on patient-rated outcomes after decompression with or without fusion for degenerative lumbar spondylolisthesis: results from the Canadian Spine Outcomes and Research Network prospective degenerative lumbar spondylolisthesis studyP-89. Abstract ID 55. Publication retraction in spine surgery: a systematic reviewP-90. Abstract ID 12. The use of a standardized surgical case log to document operative exposure to procedural competencies in a spine surgery fellowship curriculum: a university-wide initiativeP-91. Abstract ID 90. Preoperative psychosocial factors affect the outcomes experienced by patients who undergo anterior cervical discectomy and fusion surgery for cervical radiculopathyP-92. Abstract ID 91. Virtual reality for patient-specific, multidisciplinary planning of complex orthopedic oncological surgery including the spineP-93. Abstract ID 35. Malposition in robotic-assisted cortical bone trajectory screw placement: analysis of 1025 consecutive screwsP-94. Abstract ID 79. Accuracy of computer-assisted spine navigation platforms: a meta-analysis of 16 040 screwsP-95. Abstract ID 86. Which is better: percutaneous or open robot-assisted spine surgery? Prospective, multicentre study of 2524 screws in 336 patientsP-96. Abstract ID 124. Opioid use in low back pain is associated with decreased quality of life, increased disability and worse treatment outcomes: a stratified propensity score analysisP-97. Abstract ID 85. Incidence and management of deep spine surgical-site infections: a systematic review and meta-analysisP-99. Abstract ID 110. Associations of preoperative analgesic use with postoperative pain and disability after spinal surgery for cervical myelopathy and radiculopathyP-100. Abstract ID 42. Cervical myelopathy and social media: a mixed-methods analysisP-101. Abstract ID 24. The use of machine learning to predict the presence of cauda equina syndrome among patients with disc herniationP-102. Abstract ID 112. A systematic review of the content and structure of composite end points in spine surgery interventional trialsP-103. Abstract ID 106. Surveying the knowledge and attitudes of moving to a high-quality, low-carbon health care systemP-104. Abstract ID 125. Variability in treatment of adult spinal deformity, a Canadian surveyP-105. Abstract ID 83. Anterior cervical hybrid constructs reduce upper adjacent segment hypermobility compared with anterior cervical discectomy and fusionP-106. Abstract ID 48. A preliminary report of robotic screw insertion in cadaveric vertebrae using the Mazor X systemP-107. Abstract ID 54. Invasive brain–computer interface for motor restoration in spinal cord injury: a systematic reviewP-108. Abstract ID 27. A new cost-effective technique to mimic pedicle screw trajectory in cadavers: a robotic validation studyP-109. Abstract ID 14. Developments and applications of augmented and virtual reality technology in spine surgery training: a systematic reviewP-110. Abstract ID 80. Comprehensive accuracy analysis of robotic models in spine surgery: a pooled analysis of 14 462 screwsP-111. Abstract ID 99. Familial chiari malformation: a systematic reviewP-112. Abstract ID 31. Ninety-day complication and revision surgery rates using navigated robotics in thoracolumbar spine surgeryP-113. Abstract ID 111. Which baseline clinical factors and clinical indications are most correlated with outcome after lumbar fusion surgery?P-114. Abstract ID 92. Characterization of the mechanical state of human mesenchymal stem cells on micro- or nano-textured Ti6Al4V surfacesP-115. Abstract ID 72. Short-term outcomes associated with the use of macro–micro–nano rough Ti6Al4V (nanoLOCK) interbody cages in patients with lumbar spine degenerative conditionsP-116. Abstract ID 127. Introduction of a novel concept to decompress foramen magnum in chiari-1 malformation without affecting stabilityP-117. Abstract ID 57. Minimally invasive tubular lumbar decompression without fusion in lumbar stenosis with underlying deformity: Friend or foe?P-118. Abstract ID 64. The role of intraoperative ultrasound in nononcological intradural lumbar spine conditions: intradural lumbar disc herniation and subdural spinal abscessP-119. Abstract ID 120. Prospective Prophylactic Antibiotics Regimen in Spine Surgery: the PPARiSS cohortP-121. Abstract ID 70. Decompression versus decompression and fusion in cauda equina syndrome secondary to massive lumbar disc herniationP-122. Abstract ID 105. Implementation of robot-assisted surgery for elective spine surgeryP-123. Abstract ID 37. Spine surgery in patients with morbid obesity: tips and tricksP98: Abstract ID 71. Pelvic incidence is associated with reoperation for adjacent segment disease in degenerative lumbar spinal fusion surgery." Canadian Journal of Surgery 66, no. 4 Suppl 1 (August 11, 2023): S1—S53. http://dx.doi.org/10.1503/cjs.006523.

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11

Boccarusso, Luca, Fulvio Pinto, Stefano Cuomo, Dario De Fazio, Kostas Myronidis, Massimo Durante, and Michele Meo. "Design, Manufacturing, and Characterization of Hybrid Carbon/Hemp Sandwich Panels." Journal of Materials Engineering and Performance, September 3, 2021. http://dx.doi.org/10.1007/s11665-021-06186-1.

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AbstractAdvanced sandwich composite structures that incorporate foams or honeycombs as core materials, have been extensively investigated and used in various applications. One of the major limitations of the conventional materials used is their weak impact resistance and their end-of-life recyclability and overall sustainability. This paper is focused on the study of the production and mechanical characterization of hybrid sandwich panels using hemp bi-grid cores that were manufactured with an ad hoc continuous manufacturing process. Bi-grid structures were stratified in multiple layers, resulting in cores with different thicknesses and planar density. Sandwich panels made with carbon fibers skins were then subjected to Low Velocity Impact, compression and indentation and the damaged panels were investigated via CT-Scan. Results show that the high tailorability of the failure modes and the very good energy absorption properties of the hybrid material open new exciting perspectives for the development of new sandwich structures that can extend the use of natural fibers into several industrial applications.
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12

Yao, Xiaoxi, Margaret Paulson, Michael J. Maniaci, Ajani N. Dunn, Chad R. Nelson, Emma M. Behnken, Melissa S. Hart, et al. "Effect of hospital-at-home vs. traditional brick-and-mortar hospital care in acutely ill adults: study protocol for a pragmatic randomized controlled trial." Trials 23, no. 1 (June 16, 2022). http://dx.doi.org/10.1186/s13063-022-06430-6.

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Abstract Background Delivering acute hospital care to patients at home might reduce costs and improve patient experience. Mayo Clinic’s Advanced Care at Home (ACH) program is a novel virtual hybrid model of “Hospital at Home.” This pragmatic randomized controlled non-inferiority trial aims to compare two acute care delivery models: ACH vs. traditional brick-and-mortar hospital care in acutely ill patients. Methods We aim to enroll 360 acutely ill adult patients (≥18 years) who are admitted to three hospitals in Arizona, Florida, and Wisconsin, two of which are academic medical centers and one is a community-based practice. The eligibility criteria will follow what is used in routine practice determined by local clinical teams, including clinical stability, social stability, health insurance plans, and zip codes. Patients will be randomized 1:1 to ACH or traditional inpatient care, stratified by site. The primary outcome is a composite outcome of all-cause mortality and 30-day readmission. Secondary outcomes include individual outcomes in the composite endpoint, fall with injury, medication errors, emergency room visit, transfer to intensive care unit (ICU), cost, the number of days alive out of hospital, and patient-reported quality of life. A mixed-methods study will be conducted with patients, clinicians, and other staff to investigate their experience. Discussion The pragmatic trial will examine a novel virtual hybrid model for delivering high-acuity medical care at home. The findings will inform patient selection and future large-scale implementation. Trial registration ClinicalTrials.gov NCT05212077. Registered on 27 January 2022
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Todesco, Martina, Carlo Zardin, Laura Iop, Tiziana Palmosi, Pietro Capaldo, Filippo Romanato, Gino Gerosa, and Andrea Bagno. "Hybrid membranes for the production of blood contacting surfaces: physicochemical, structural and biomechanical characterization." Biomaterials Research 25, no. 1 (August 10, 2021). http://dx.doi.org/10.1186/s40824-021-00227-5.

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Abstract Background Due to the shortage of organs’ donors that limits biological heart transplantations, mechanical circulatory supports can be implanted in case of refractory end-stage heart failure to replace partially (Ventricular Assist Device, VAD) or completely (Total Artificial Heart, TAH) the cardiac function. The hemocompatibility of mechanical circulatory supports is a fundamental issue that has not yet been fully matched; it mostly depends on the nature of blood-contacting surfaces. Methods In order to obtain hemocompatible materials, a pool of hybrid membranes was fabricated by coupling a synthetic polymer (polycarbonate urethane, commercially available in two formulations) with a decellularized biological tissue (porcine pericardium). To test their potential suitability as candidate materials for realizing the blood-contacting surfaces of a novel artificial heart, hybrid membranes have been preliminarily characterized in terms of physicochemical, structural and mechanical properties. Results Our results ascertained that the hybrid membranes are properly stratified, thus allowing to expose their biological side to blood and their polymeric surface to the actuation system of the intended device. From the biomechanical point of view, the hybrid membranes can withstand deformations up to more than 70 % and stresses up to around 8 MPa. Conclusions The hybrid membranes are suitable for the construction of the ventricular chambers of innovative mechanical circulatory support devices.
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Maenpaa, M., I. Kujala, E. Harjulahti, I. Stenstrom, W. Nammas, J. Knuuti, A. Saraste, and T. Maaniitty. "Hybrid CTA/PET imaging of coronary artery disease in non-diabetic, prediabetic and diabetic patients evaluated for chest pain." European Heart Journal - Cardiovascular Imaging 24, Supplement_1 (June 2023). http://dx.doi.org/10.1093/ehjci/jead119.340.

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Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Academy of Finland Finnish foundation for cardiovascular research. Background Patients with prediabetes or diabetes are at increased risk of developing cardiovascular disease and cardiac events. First-line coronary computed tomography angiography (CTA) followed by selective use of positron emission tomography (PET) myocardial perfusion imaging is a feasible strategy to diagnose and risk-stratify patients with suspected coronary artery disease (CAD). Purpose To study whether prediabetes or diabetes affects the relationship between imaging-defined CAD and patient outcome. Methods We retrospectively identified consecutive symptomatic patients who underwent coronary CTA for suspected CAD. In patients with suspected obstructive CAD on CTA, myocardial ischemia was routinely evaluated by 15O-water PET myocardial perfusion imaging. The relationship of CAD phenotype and long-term outcome was investigated according to patient’s diabetic status. A composite outcome included all-cause mortality, myocardial infarction (MI), and unstable angina pectoris. Results A total of 1743 patients were included: 1214 (70%) non-diabetic, 259 (15%) prediabetic, and 270 (16%) type 2 diabetic patients. During 6.43 years of follow-up, 164 (9%) adverse events occurred, including 106 deaths, 41 MIs and 17 episodes of unstable angina. The prevalence of normal coronary arteries on CTA was highest in the non-diabetic patients (39%). The prevalence of hemodynamically significant CAD (i.e., obstructive stenosis and abnormal perfusion) increased from 14% in non-diabetic patients to 20% in prediabetic and to 27% in diabetic patients. The lowest event rate was seen in patients with normal coronary arteries (annual event rate 0.2%) and highest in patients with concomitant type 2 diabetes and hemodynamically significant CAD (annual event rate 4.7%). However, neither prediabetes nor diabetes were independent predictors of the composite adverse outcome after adjustment for the clinical risk factors and imaging findings. Conclusions Coronary CTA followed by selective downstream use of PET myocardial perfusion imaging predicts long-term outcome similarly in type 2 diabetic, prediabetic, and non-diabetic patients.
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Kogame, N., R. Modolo, P. Chichareon, H. Komiyama, D. Taggart, J. Escaned, A. Banning, V. Farooq, Y. Onuma, and P. W. Serruys. "121Clinical impact of residual SYNTAX score after physiology guided state-of-art PCI in 3VD: insight from the SYNTAX II trial." European Heart Journal 40, Supplement_1 (October 1, 2019). http://dx.doi.org/10.1093/eurheartj/ehz747.0037.

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Abstract Background The clinical implication of residual SYNTAX score in patients treated with state-of- art PCI including hybrid iFR-FFR for three vessel disease is undetermined. Purpose The purpose of this study was to investigate the clinical impact of residual SYNTAX Score (rSS) after hybrid iFR-FFR guided state-of-art PCI in patients with three vessel disease (3VD). Methods The SYNTAX-II study was a multicentre, single arm study that investigated the impact of the state-of-art PCI strategy on clinical outcomes in 454 patients with de novo 3VD, without left main disease. All the patients treated with the state-of-art PCI in the SYNTAX II trial were retrospectively screened and analysed for rSS. The rSS was defined as the SYNTAX Score (SS) recalculated after PCI. The state-of-art PCI strategy included: heart team decision-making utilizing the SYNTAX score II, hybrid iFR-FFR decision-making strategy, intravascular ultrasound guided stent implantation, contemporary chronic total occlusion revascularization techniques and guideline-directed medical therapy. The primary endpoint of this substudy was major adverse cardiac and cerebrovascular events (MACCE – a composite of all-cause death, any stroke, myocardial infarction, or revascularization) at 2 years. Patients with rSS were stratified according to angiographically complete revascularization (rSS of 0) and previously proposed rSS cut-off value of 8 (>0 to 8, and >8). Results A total of 454 patients were screened and rSS were analysable in 441 patients (97.1%). Before PCI, anatomical SS was 20.3±6.4 which was after PCI reduced to 3.9±4.5 (rSS). Only 67 patients (15.2%) had rSS >8 (mean 12.3±4.1). Two-year MACCE occurred in 58 patients (13.2%). Patients with MACCE had similar rSS to those without MACCE (2.0 (IQR: 0.0 to 6.0) vs. 2.0 (IQR: 0.0 to 5.0), p=0.313). Kaplan-Meier analysis showed similar 2- year incidence of MACCE with rSS stratifications (rSS of 0 (n=140): 15.0%, >0 to 8 (n=234): 12.0%, >8 (n=67): 13.4%, log-rank p for overall = 0.703). Conclusion After hybrid iFR-FFR guided state-of-art PCI in 3VD, residual SYNTAX Score was very low, suggesting that complete or reasonable incomplete revascularization was achieved in majority of cases. Previously proposed rSS cut-off value of 8 was not associated with a worse clinical outcome. Acknowledgement/Funding European Cardiovascular Research Institute (ECRI) with unrestricted research grants from Volcano and Boston Scientific
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Zhang, Bowen, Xiaogang Sun, Yanxiang Liu, Yaojun Dun, Shenghua Liang, Cuntao Yu, Xiangyang Qian, et al. "Hybrid Technique on the Total Arch Replacement for Type A Aortic Dissection: 12-year Clinical and Radiographical Outcomes From a Single Center." Frontiers in Cardiovascular Medicine 9 (February 28, 2022). http://dx.doi.org/10.3389/fcvm.2022.820653.

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ObjectiveHybrid total arch replacement (HTAR) was an alternative for type A aortic dissection (TAAD). This study aimed to evaluate the clinical and radiographical outcomes of HTAR for TAAD and to evaluate the clinical outcomes of performing this procedure under mild hypothermia.MethodsA total of 209 patients who underwent HTAR for TAAD were retrospectively analyzed and stratified into mild (n = 48) and moderate (n = 161) hypothermia groups to evaluate the effects of mild hypothermia on the clinical outcomes. Long-term clinical outcomes were evaluated by the overall survival and adverse aortic events (AAEs). A total of 176 patients with preoperative and at least one-time postoperative aortic computed tomography angiography in our institute were included for evaluating the late aortic remodeling (aortic diameter and false lumen thrombosis).ResultsThe median follow-up period was 48.3 (interquartile range [IQR] = 28.4–73.7) months. The overall survival rate was 88.0, 83.2, and 77.1% at the 1, 5, and 10 years, respectively, and in the presence of death as a competing risk, the cumulative incidence of AAEs was 4.8, 9.9, and 12.1% at the 1, 5, and 10 years. The aortic diameters were stable in the descending thoracic and abdominal aorta (P > 0.05 in all the measured aortic segments). A total of 100% complete false lumen thrombosis rate in the stent covered and distal thoracic aorta were achieved at 1 year (64/64) and 4 years (18/18), respectively after HTAR. The overall composite adverse events morbidity and mortality were 18.7 and 10.0%. Mild hypothermia (31.2, IQR = 30.2–32.0) achieved similar composite adverse events morbidity (mild: 14.6 vs. moderate: 19.9%, P = 0.41) and early mortality (mild: 10.4 vs. moderate: 9.9%, P = 1.00) compared with moderate hypothermia (median 27.7, IQR = 27–28.1) group, but mild hypothermia group needed shorter cardiopulmonary bypass (mild: 111, IQR = 93–145 min vs. moderate: 136, IQR = 114–173 min, P < 0.001) and aortic cross-clamping (mild: 45, IQR = 37–56 min vs. moderate: 78, IQR = 54–107 min, P < 0.001) time.ConclusionHybrid total arch replacement achieved desirable early and long-term clinical outcomes for TAAD. Performing HTAR under mild hypothermia was as safe as under moderate hypothermia. After HTAR for TAAD, dissected aorta achieved desirable aortic remodeling, presenting as stable aortic diameters and false lumen complete thrombosis. In all, HTAR is a practical treatment for TAAD.
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Harskamp, Ralf E., Henry A. Liberman, Rajendra H. Mehta, Wissam Jaber, Thomas A. Vassiliades, Habib Samady, and Michael E. Halkos. "Abstract 17781: Surgical Revascularization in Acute Coronary Syndromes: Minimally Invasive Hybrid Strategy versus Conventional Coronary Artery Bypass Grafting." Circulation 132, suppl_3 (November 10, 2015). http://dx.doi.org/10.1161/circ.132.suppl_3.17781.

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Background: Hybrid coronary revascularization (HCR), which combines minimally invasive bypass surgery and percutaneous coronary intervention of non-LAD vessels, constitute a less invasive alternative to conventional coronary artery bypass grafting (CABG). The safety and effectiveness of HCR in acute coronary syndromes (ACS) as a surgical coronary revacularization strategy is unknown. Methods: Patients presenting with ACS who underwent HCR at a U.S. academic center (1/2008-9/2013) were included. These patients were matched 1:4 to similar individuals who underwent CABG using a propensity-score matching algorithm. Conditional logistic regression and Cox regression stratified on matched pairs were performed to evaluate the association of HCR versus CABG on the outcomes of 30-day MACCE (a composite of mortality, myocardial infarction (MI) and stroke), peri-procedural complications, and 3-year mortality. Results: Of 585 patients (HCR=117, CABG=468) in the propensity-score matched cohort, the 30-day MACCE was comparable after HCR and CABG (4.3% vs. 3.6%, odds ratio: 1.19, 95%-CI:0.43-3.19, p=0.75). Compared with CABG, HCR resulted in fewer procedural complications (7.7% vs. 16.0%, p=0.037), fewer blood transfusions (0 95%-CI:0-0 vs 1 95%-CI:0-2, p<0.001), lower chest-tube drainage (760cc 95%-CI:555-1090 vs. 890cc 95%-CI:660-1130, p<0.001) and shorter length-of-stay (4, 95%-CI:3-5 versus 5, 95%-CI:4-7 days, p<0.001). Over a 3-year follow-up period, mortality was similar after HCR and CABG (6.0% vs. 7.0%, hazard ratio: 0.92, 95%-CI:0.33-2.54, p=0.87). Conclusion: In this exploratory analysis we found that among patients with ACS the use of HCR appeared safe, with fewer procedural complications, less blood product use, and faster recovery with similar longitudinal outcomes relative to conventional CABG surgery. Future multi-center studies involving a large number of patients with ACS are needed to confirm these findings.
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