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Статті в журналах з теми "Stade prénatal"
Rodrigue, Catherine. "Le diagnostic prénatal ou un bébé « normal » svp !" Dossier : La bioéthique 2, no. 2 (April 13, 2018): 27–34. http://dx.doi.org/10.7202/1044647ar.
Повний текст джерелаDonner, C., and J. Désir. "Noninvasive prenatal testing (NIPT) : state of the art." Revue Medicale de Bruxelles 40, no. 2 (2019): 111–16. http://dx.doi.org/10.30637/2019.18-096.
Повний текст джерелаAdolphe, KOUADIO Kouassi Kan, Fêtê Ernest KOFFI, and Sangaré Moussa. "Représentation Sociale De La Grossesse, Rapport À La Grossesse Et Consultations Prénatales Dans La Sous-Préfecture De Kokomian." Research and Analysis Journal 4, no. 12 (December 28, 2021): 15–21. http://dx.doi.org/10.18535/raj.v4i12.267.
Повний текст джерелаДисертації з теми "Stade prénatal"
Zhu, Hongmei. "Prenatal dysfunctions of chloride-related inhibition in lumbar motoneurons of the SOD1G93A ALS." Electronic Thesis or Diss., Bordeaux, 2023. http://www.theses.fr/2023BORD0026.
Повний текст джерелаAmyotrophic lateral sclerosis (ALS) is a fatal and adult-onset neurodegenerative disease characterized by a progressive degeneration of motoneurons (MNs) with complex multifactorial aetiology. Most ALS studies have focused on symptomatic stages based on the hypothesis that ALS pathogenesis occurs when the disease becomes symptomatic. However, growing evidence indicates that ALS pathogenesis might start long before symptom onset. My PhD thesis work was based on the hypothesis that ALS - familial and sporadic - stems from deficits taking place during early development. With the aim of identifying early changes underpinning ALS neurodegeneration, the first part of my thesis analysed the GABAergic/glycinergic inhibitory postsynaptic currents (IPSCs) to embryonic (E) E17.5 MNs located in the ventro-lateral motor column from SOD1G93A (SOD) mice, in parallel with the analyse of chloride homeostasis. Our results showed that IPSCs are less frequent in SOD animals in accordance with a reduction of synaptic VIAAT-positive terminals in the close proximity of MN somata. SOD MNs exhibited an ECI 10 mV more depolarized than wild type (WT) MNs. This deficit in GABA/glycine inhibition was due to a reduction of the neuronal chloride transporter KCC2. SOD spontaneous IPSCs and evoked GABAAR-currents exhibited a slower decay correlated to elevated [Cl-]i. Using computer modelling approach, we revealed that the slower relaxation of synaptic inhibitory events acts as a compensatory mechanism to strengthen or increase the efficacy of GABA/glycine inhibition when ECI is more depolarized. Interestingly, simulations revealed an excitatory effect of low frequency (<50Hz) depolarizing GABA/glycine post-synaptic potentials (dGPSPs) in SOD-like MNs but not in WT-like littermates. At high frequency, dGPSPs switched to inhibitory effect resulting from the summation of the shunting components. The second part of my PhD thesis focussed on the effect of electrically evoked-dGPSPs, at different frequencies (7.5 to 100 Hz), on real lumbar E17.5 MNs in which a depolarized ECI (below spike threshold) was imposed. The aim was to examine whether the excitatory effect could be linked to morphological changes previously described in E17.5 SOD MNs. Results showed that some MNs were excited by low frequency dGPSPs and inhibited by high frequency dGPSPs (Dual MNs) and others were inhibited at all frequencies (Inhibited MNs). Dual effect was more often detected in SOD MNs. WT MNs were classified into two clusters according to their input resistance (Rin), Dual MNs being specific to high Rin and Inhibited MNs to low Rin. Morphometric data pointed out a reduced dendritic tree in high Rin WT Dual MNs and a large dendritic tree in low Rin Inhibited MNs. This was not the case in SOD MNs that were excited or inhibited whatever their morphology and Rin. In agreement with simulation showing that a less density of inhibitory current on MNs soma favours excitatory dGPSPs, we found less synaptic VIAAT terminals on the soma and proximal dendrites of SOD MNs, compared to littermate WT MNs, as well as a lower frequency of spontaneous dGPSPs. Altogether, my thesis data emphasize a prenatal defect in the CI- homeostasis and GABA/glycine innervation in the SOD1G93A ALS MNs. Before birth, a dominant population of MNs with low Rin emerges in WT animals. These MNs that are inhibited by dGPSPs could represent future ALS vulnerable fast MNs (putative FF). Interestingly, those MNs are not inhibited in SOD animals. The inhibitory dysfunction could be attributed to two distinct factors: morphology and perisomatic inhibitory synapse density. Of these two factors, the latter plays a major role by controlling capability of GABAergic/glycinergic neurons for shaping spinal motor output
Lange, Léa. "Influences environnementales précoces et plasticité phénotypique : étude d’un modèle amphibien avec soins parentaux prénataux, l’Alyte accoucheur." Thesis, La Rochelle, 2020. http://www.theses.fr/2020LAROS016.
Повний текст джерелаThe common Midwife toad (Alytes obstetricans) is a species of amphibian in which parental care is performed exclusively by the male. Indeed, after mating, during which the male actively helps the female for the emission of the eggs, he attaches the clutch around the joints of his hind limbs and thus carries it throughout embryonic development. Amphibians are very sensitive to the abiotic environment, especially to hydric and thermal conditions. To avoid extreme temperatures, they can behaviourally thermoregulate, for example by selecting refuges with favourable microclimatic conditions. The common Midwife toad has shown a selection of their refuges based on their hydric and thermal properties. The early stages of development are particularly sensitive to temperature. Parents can then carry out parental care to limit the effects. A paternal phenological effect has been observed in common Midwife toad, whose males favour higher temperatures when they carry eggs. Parental care is costly for adults, however. The common Midwife toad exhibited decreased locomotion performances during egg carrying, which could lead to decreased fitness. In addition, parental care strongly influences the development of young. The thermal environment encountered during the embryonic stage, and therefore during the period of parental care in the common Midwife toad, had both short-term and persistent effects on the phenology. The thermal environment encountered during the larval stage can also be decisive. In the common Midwife toad, the postnatal thermal environment induced a switch to multi-year development during development at 16 ° C, with overwintering at the tadpole stage, whereas it was annual during development at 20 ° C and 24 ° C. The postnatal thermal environment has also involved morphological, physiological, and behavioural changes. Finally, an involvement of physiology, and in particular heart rate, has been observed throughout the embryonic and larval development of the young
Книги з теми "Stade prénatal"
Robinson, Lynne, and Jacqueline Knox. Pilates Pregnanacy Guide: Optimum Health and Fitness for Every Stage of Your Pregnancy. Firefly Books, 2006.
Знайти повний текст джерелаЧастини книг з теми "Stade prénatal"
"Le développement moteur du stade prénatal à l’adolescence." In Motricité humaine - Tome 2, 135–266. Presses de l'Université du Québec, 2003. http://dx.doi.org/10.2307/j.ctv18ph6rw.7.
Повний текст джерела