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Статті в журналах з теми "Slu7-2"

1

Xu, Deming, Deborah J. Field, Shou-Jiang Tang, Arnaud Moris, Brian P. Bobechko, and James D. Friesen. "Synthetic Lethality of Yeast slt Mutations with U2 Small Nuclear RNA Mutations Suggests Functional Interactions between U2 and U5 snRNPs That Are Important for Both Steps of Pre-mRNA Splicing." Molecular and Cellular Biology 18, no. 4 (April 1, 1998): 2055–66. http://dx.doi.org/10.1128/mcb.18.4.2055.

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ABSTRACT A genetic screen was devised to identify Saccharomyces cerevisiae splicing factors that are important for the function of the 5′ end of U2 snRNA. Six slt (stands for synthetic lethality with U2) mutants were isolated on the basis of synthetic lethality with a U2 snRNA mutation that perturbs the U2-U6 snRNA helix II interaction. SLT11 encodes a new splicing factor andSLT22 encodes a new RNA-dependent ATPase RNA helicase (D. Xu, S. Nouraini, D. Field, S. J. Tang, and J. D. Friesen, Nature 381:709–713, 1996). The remaining four sltmutations are new alleles of previously identified splicing genes:slt15, previously identified as prp17(slt15/prp17-100), slt16/smd3-1,slt17/slu7-100, and slt21/prp8-21. slt11-1 andslt22-1 are synthetically lethal with mutations in the 3′ end of U6 snRNA, a region that affects U2-U6 snRNA helix II; however,slt17/slu7-100 and slt21/prp8-21 are not. This difference suggests that the latter two factors are unlikely to be involved in interactions with U2-U6 snRNA helix II but rather are specific to interactions with U2 snRNA. Pairwise synthetic lethality was observed among slt11-1 (which affects the first step of splicing) and several second-step factors, includingslt15/prp17-100, slt17/slu7-100, andprp16-1. Mutations in loop 1 of U5 snRNA, a region that is implicated in the alignment of the two exons, are synthetically lethal with slu4/prp17-2 and slu7-1 (D. Frank, B. Patterson, and C. Guthrie, Mol. Cell. Biol. 12:5179–5205, 1992), as well as with slt11-1, slt15/prp17-100,slt17/slu7-100, and slt21/prp8-21. These same U5 snRNA mutations also interact genetically with certain U2 snRNA mutations that lie in the helix I and helix II regions of the U2-U6 snRNA structure. Our results suggest interactions among U2 snRNA, U5 snRNA, and Slt protein factors that may be responsible for coupling and coordination of the two reactions of pre-mRNA splicing.
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2

Gárate-Rascón, María, Miriam Recalde, Maddalen Jimenez, María Elizalde, María Azkona, Marina Bárcena-Varela, Leticia Colyn, et al. "SLU7 downregulation potentiates liver damage through hepatic de-differentiation." Journal of Hepatology 73 (August 2020): S212. http://dx.doi.org/10.1016/s0168-8278(20)30930-2.

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Tobing, Edward ML. "UJI SENSITIVITAS VOLUME SLUG PADA INJEKSI ALKALI MELALUI MODEL SIMULASI CORE FLOODING EOR." Lembaran publikasi minyak dan gas bumi 53, no. 1 (April 2, 2019): 15–27. http://dx.doi.org/10.29017/lpmgb.53.1.360.

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Penerapan salah satu metode enhanced oil recovery (EOR) yaitu menginjeksikan alkali ke dalam reservoir dengan tujuan agar dapat meningkatkan produksi dari lapangan minyak tua. Fungsi alkali adalah untuk menurunkan tegangan antar muka dan mengubah sifat kebasahan batuan dari oil wet menjadi water wet. Tulisan ini membahas tentang pengembangan model simulasi coreflooding injeksi alkali dengan menggunakan data percobaan di laboratorium, dan validasi dari model simulasi tersebut dilakukan dengan cara menyelaraskan terhadap hasil uji coreflooding. Percobaan coreflooding alkali dilakukan pada core standar batu pasir Bentheimer sampai tahap produksi tersier dalam kondisi reservoir, yang dibagi dalam 5(lima) segmen slug: (1). Slug Alkali dengan konsentrasi NaOH 0.005 fraksi mol sebanyak 0.25 Pore Volume. (2). Slug Polimer spike dengan konsentrasi polimer 4.0x10-6 fraksi mol sebanyak 0.25 PV. (3). Slug Decreasing polimer-1 dengan konsentrasi polimer 3.2x10-6 fraksi mol sebanyak 0.25 PV. (4). Slug Decreasing polimer-2 dengan konsentrasi polimer 2.56x10-6 fraksi mol sebanyak 0.25 PV. (5). Slug air sebanyak 2.0 PV. Dari hasil uji core flooding tersebut menunjukkan perolehan minyak sebesar 68.75% original in place dari saturasi minyak tersisa setelah injeksi air. Analisis uji sensitivitas dilakukan dengan mengkombinasikan secara bertahap volume slug alkalin, slug polimer-spike, slug decreasing-polimer-1, slug decreasing-polimer-2 dan slug air untuk memperkirakan adanya perubahan perolehan minyak dengan serangkaian run model simulasi. Berdasarkan hasil uji sensitivitas tersebut, maka perolehan minyak maksimum didapat sebesar 81.41% original in place dari saturasi minyak tersisa untuk kasus volume slug: alkali 0.15PV, polimer-spike 0.30PV, decreasing polimer-1 sebanyak 0.30PV, decreasing-polimer-2 sebanyak 0.25PV dan slug air 1.5PV. Atau bertambah 12.65 % original in place dari saturasi minyak tersisa dibandingkan hasil uji coreflooding.
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Kim, Joori, In-Ho Kim, Han Hee Lee, Sung Hak Lee, and Jae Myung PARK. "Slug overexpression and association with clinicopathological features in gastric cancer." Journal of Clinical Oncology 38, no. 4_suppl (February 1, 2020): 426. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.426.

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426 Background: Slug is a suppressive transcriptional factor of E-cadherin, acting as an activator of epithelial-mesenchymal transition(EMT). Its clinical relevance in gastric cancer(GC) is not fully known. Methods: Our study evaluated the expression patterns of EMT and cancer stem cell markers in GC patients who had clinical stage 2-3, underwent gastrectomy, D2 lymph node dissection (LND), adjuvant chemotherapy. Immunohistochemistry of E-cadherin, vimentin, CD133, ABCG2, NEDD9, SMAD4, XB130, Slug, Snail were investigated from 210 gastric cancer samples using tissue microarrays. The correlation between each markers expressed and the association with clinicopathological factors were analyzed. Results: Slug expression was more frequent in stage 3 than stage 2 (p=0.000), advanced T (p=0.007) and N stage (p=0.001), while histologic type did not make difference. Slug expression correlated with the expression of cancer stem cell marker CD133 (r=0.180, p=0.015) and CD133 expression was also related with ABCG2 (r=0.412, p=0.000). High Slug group showed shorter overall survival, compared to low Slug group (median OS 134 vs 124 months, p=0.044). The 2-year and 5-year disease-free (DF) rate for patients with high Slug and low Slug was 87.1% and 79.8%, 68.1% and 79.8%, respectively(p=0.038). The DFS curve reached an earlier plateau at 11-month in low Slug group, while in high Slug group took as long as 99 months. A multivariate analysis using the Cox proportional hazards regression model demonstrated Slug to be an independent prognostic factor for overall survival; hazard ratio 0.504 [95% CI 0.278-0.916] (p=0.025). Conclusions: In stage 2-3 GC patients who underwent gastrectomy with D2 LND and adjuvant chemotherapy, high Slug expression is associated with better disease-free and overall survival. Patients may benefit by testing Slug immunohistochemistry to predict prognosis after gastrectomy.
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Telmesani, Reem, Jada A. H. White, and Aaron B. Beeler. "Liquid-Liquid Slug-Flow-Accelerated [2+2] Photocycloaddition of Cinnamates." ChemPhotoChem 2, no. 10 (June 6, 2018): 865–69. http://dx.doi.org/10.1002/cptc.201800081.

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Telmesani, Reem, Jada A. H. White, and Aaron B. Beeler. "Liquid-Liquid Slug-Flow-Accelerated [2+2] Photocycloaddition of Cinnamates." ChemPhotoChem 2, no. 10 (October 2018): 829. http://dx.doi.org/10.1002/cptc.201800192.

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KENNEDY, T. F., J. CONNERY, T. FORTUNE, D. FORRISTAL, and J. GRANT. "A comparison of the effects of minimum-till and conventional-till methods, with and without straw incorporation, on slugs, slug damage, earthworms and carabid beetles in autumn-sown cereals." Journal of Agricultural Science 151, no. 5 (September 19, 2012): 605–29. http://dx.doi.org/10.1017/s0021859612000706.

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SUMMARYThe present study compared slug, earthworm and carabid beetle abundance and slug damage to plants in minimum tillage (MT) and conventional tillage (CT) autumn-sown cereals. Winter barley was sown by CT and MT for 3 years followed by winter wheat for 6 years on a light-textured soil (Trial 1). Each cultivation was split so that straw was incorporated into the soil during cultivation in one split while the other did not receive straw. A similar investigation with winter wheat, over the same period, was undertaken on a nearby heavy-textured soil (Trial 2). The effects of method of cultivation and soil incorporation of straw on slug abundance and damage, and on earthworm populations were measured. Additionally, at Trial 1, the effects of cultivation and straw treatments on carabid beetle occurrence were measured in years 5–9. Over the 9 years, the method of cultivation had a significant effect on slug numbers in each trial. Slugs were more numerous in MT than CT plots, significantly so in 3 of the 9 years in Trial 1 and in 5 years in Trial 2. In Trial 1, slug numbers were significantly greater on no-straw than straw plots in 3 years as well as for the 9 years combined. Slug numbers did not differ between straw and no-straw plots in Trial 2. Slug numbers varied significantly between years and were influenced by factors other than the method of cultivation and straw application. Slug damage to seed and seedlings was quite low in each year (1–2%). Slug damage to cereal leaves at GS 23 was widespread in both trials, and severe in some years. MT had more leaf damage than CT in 5 of the 9 years in each trial, significantly so in 3 years in Trial 1 and in 4 years in Trial 2. Straw did not affect leaf damage in either MT or CT. Slug damage was not related to, nor did it affect either ear density or grain yield. The dominant slug species was Deroceras reticulatum. Earthworm numbers were significantly greater in MT than CT, for combined years, in each trial. Annually, these differences were significant for 5 years in Trial 1 and 2 years in Trial 2. Straw plots had significantly more earthworms than no-straw, for combined years, in each trial. The latter differences were significant for 5 years in Trial 1 and 3 years in Trial 2. In MT, the positive effect of straw on earthworm numbers was significant in Trial 2 but not in Trial 1. In CT, the latter effect was significant in each trial. Lumbricus species were more numerous in MT than CT and in straw than no-straw treatments. The impact of cultivation on numbers of carabid beetles was species-specific. The large beetle, Pterostichus melanarius, was significantly more numerous in MT than CT in 2 of the 5 years and for the aggregate of 5 years. Small carabids (Bembidion species and Trechus quadristriatus) were significantly more abundant in CT than MT in 3 of the 5 years as well as for the aggregate of 5 years. Straw did not affect the number of any or all carabid species either for combined cultivations (MT + CT) or within either MT or CT. It is concluded that MT increases slug numbers, slug damage and earthworm numbers relative to CT cultivations. MT favours large carabid beetles and CT favours small beetles. Straw incorporation increases earthworm numbers but not slugs, slug damage or carabid beetles. Slug damage to cereal leaves does not affect ear density or grain yield in either MT or CT crops when sown to a depth of 40 mm and before 18 September.
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Ernawati, Masitoh, Kismartini Kismartini, and Maryono Maryono. "The Evaluation Of Slums Level In Jatibarang, Semarang." E3S Web of Conferences 73 (2018): 03019. http://dx.doi.org/10.1051/e3sconf/20187303019.

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One of the village that get first priority in slums handling in in Semarang City based on mayor decree of Semarang’s number 050/801/2014 is Jatibarang Village. According the Ministry of Public Works through the KOTAKU (Kota Tanpa Kumuh) Program, in 2017 Jatibarang Village received funding for road and drainage construction. This research is to evaluate the slum reduction of road and drainage construction in a neighborhood. The method of research is quantitative and comparative through data calculation on 2 (two) criteria after handling and compari ed with baseline data. Based on the results of the research it can be seen that the slum handling of 2 (two) slum criteria did not give big impact to the slum value that is 40 before the handling and 30 after handling with the difference of 10 points. The results of this research indicate that there is still a need for handling slum reduction in this area. It is also necessary to evaluate the value of slum periodically of slum areas that have been set in order to know the changes that occur. involving the local community in the maintenance of settlement environment is necessary as well, so it is expected that the slum reduction increases, insteade of decreasing..
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Kirino, Yutaka. "7-2 Associative learning in the terrestrial slug." Neuroscience Research Supplements 18 (January 1993): S14. http://dx.doi.org/10.1016/s0921-8696(05)80708-x.

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Sun, Yan, Zack Zhengyu Wang, and Wen-Shu Wu. "Slug Is Required for a Functional Hematopoietic Stem Cell (HSC) Niche." Blood 116, no. 21 (November 19, 2010): 2579. http://dx.doi.org/10.1182/blood.v116.21.2579.2579.

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Abstract Abstract 2579 Slug belongs to the highly conserved Slug/Snail family of zinc-finger transcription factors found in diverse species ranging from C. elegans to humans. Our previous study has already demonstrated that Slug serves intrinsic role in the regulation of HSC fates (Blood, 2010, 115(9):1709-1717). There is bone defect in Slug-/- mice, while Slug is expressed in osteoblast cells which are niche cells for HSCs, suggesting that Slug might be also extrinsically required for HSC regulation. To address this issue, the following experiments and assays were performed. Firstly, the cell proliferation of wild-type (WT) hematopoietic stem/progenitor cells (HS/PCs) (loaded with carboxyfluorescein succinimidyl ester (CFSE)) placed on bone marrow (BM) stromal layers (prepared from either Slug-/- or WT mice) was analyzed. Co-culture proliferation assay illustrated a clear increasing in the ability of Slug-/-BM stroma to support normal proliferation of WT HS/PCs, suggesting a significant and qualitative change in Slug-/- BM stromal cells so that they were able to support normal proliferation by Slug-competent HS/PCs. Secondly, BM microenvironment altered by Slug deficiency was defined by RT-PCR. Slug-/- BM had altered cell cycle profiles associated with increased stromal Notch1, N-cadherin, Vcam and Angiopoietin-1 expression. These findings indicate that Slug may participate in signaling in BM niche cells and thus is capable of influencing their function. Thirdly, the transplantation analysis was performed to address whether Slug impact was stem cell stroma dependent. WT hematopoietic cells in Slug knockout environment (8 weeks after transplantation) displayed a dramatic increase in LSK and LSK-Flk-2 ratio and in total number in BM, but not in spleen, indicating a stroma-determined effect by Slug on HSCs. It also showed a mobilization phenotype similar to that originally observed in Slug+/+ environment. Moreover, the annexin V apoptosis assay and cell-cycle analysis by the Edu incorporation assay suggested that Slug deficiency microenvironment promoted HSC expansion largely by increasing their proliferation, but not cell survival. Fourthly, each cell lineage in BM and spleen after WT BM transplanted into Slug+/+ and Slug-/- recipients was fully analyzed. The total number and ratio of T cells (CD3e, CD4+CD8-, CD4-CD8+ and CD4+CD8+) was markedly decreased in BM, but not in spleen, while the other lineages (granulocytes CD11b+Gr-1+, macrophages CD11b+, immature B lymphoid IgM-B220+, mature B lymphoid IgM+B220+, mature Erythroid CD71-Ter119+, and immature erythroid CD71+Ter119+) had an equivalent number and ratio in BM and spleen. Overall, Slug-/- BM microenvironment results in T cell loss. Finally, the recent study shows BM adipocytes as negative regulators of haematopoietic microenvironment, while the in vivo and in vitro evidences indicate that Slug is a key regulator of the adipocyte differentiation. Thus, in this study, we try to address whether Slug as a key factor adjusts adipocytes in BM niche. The fat of the whole body and the femurs and tibias were measured by DXA (Dual-energy X-ray Absorptiometry). Our data showed Slug-/- mice at 8 wk of age had lowest total fat, as well as ROI (region of interest) fat compared to Slug+/+ mice. In vitro adipocyte differentiation assay indicated there was less adipocyte formation from Slug-/- MSCs from BM. Furthermore, a dramatic loss of adipocytes in the femur in Slug-/- recipient was observed in 8 weeks after transplanting WT hematopoietic cells into Slug+/+ and Slug-/- recipients. Combining the above-mentioned data from WT hemtopoisis in Slug-/- microenvironment showed a dramatic increase in LSK and LSK-Flk-2 ratio and total numbers, lack of BM adipocytes after irradiation in fatless mice (Slug-/- recipient), suggesting a role of Slug-/- BM microenvironment in enhancing haematopoietic progenitor expansion via inhibition of BM adipocytes and post-transplant recovery. Taken together, our previously and present findings demonstrate that Slug serves intrinsic and extrinsic roles in the regulation of HSC fates. Disclosures: No relevant conflicts of interest to declare.
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Дисертації з теми "Slu7-2"

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Wang, Hongwei. "CO 2corrosion mechanistic modeling in horizontal slug flow." Ohio University / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1178306674.

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2

Toppila, Timo, Ulrich Rohde, Bengt Hemström, Yuri Bezrukov, and Sören Kliem. "The European project FLOMIX-R: Description of the slug mixing and buoyancy related experiments at the different test facilities(Final report on WP 2)." Forschungszentrum Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-28632.

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The goal of the work described in this report was the experimental investigation of the mixing of coolant with different quality (temperature, boron concentration) in nuclear reactors on the way from the cold leg through the downcomer and lower plenum to the core inlet in a systematic way. The obtained data were used for the clarification of the mixing mechanisms and form a data basis for the validation of computational fluid dynamics (CFD) codes. For these purposes, experiments on slug mixing have been performed at two test facilities, modelling different reactor types in scale 1:5, the Rossendorf and Vattenfall test facilities. The corresponding accident scenario is the start-up of first main coolant pump (MCP) after formation of a slug of lower borated water during the reflux-condenser mode phase of a small break loss of coolant accident (LOCA). The matrices for the experiments were elaborated on the basis of the key phenomena, being responsible for the coolant mixing during pump start-up. Slug mixing tests have also been performed at the VVER-1000 facility of EDO Gidropress to meet the specifics of this reactor type. The mixing of slugs of water of different quality is also very important for pre-stressed thermal shock (PTS) situations. In emergency core cooling (ECC) situations after a LOCA, cold ECC water is injected into the hot water in the cold leg and downcomer. Due to the large temperature differences, thermal shocks are induced at the reactor pressure vessel (RPV) wall. Temperature distributions near the wall and temperature gradients in time are important to be known for the assessment of thermal stresses. One of the important phenomena in connection with PTS is thermal stratification, a flow condition with a vertical temperature profile in a horizontal pipe. Due to the fluctuating character of the flow, this may cause thermal fatigue in the pipe. Besides of thermal fatigue, a single thermal shock can also be relevant for structural integrity, if it is large enough, especially in the case, that the brittle fracture temperature of the RPV material is reduced due to radiation embrittlement. Therefore, additional to the investigations of slug mixing during re-start of coolant circulation, the mixing of slugs or streams of water with higher density with the ambient fluid in the RPV was investigated. The aim of these investigations was to study the process of turbulent mixing under the influence of buoyancy forces caused by the temperature differences. Heat transfer to the wall and thermal conductivity in the wall material have not been considered. Experiments on density driven mixing were carried out at the Rossendorf and the Fortum PTS facilities.
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3

Toppila, Timo, Ulrich Rohde, Bengt Hemström, Yuri Bezrukov, and Sören Kliem. "The European project FLOMIX-R: Description of the slug mixing and buoyancy related experiments at the different test facilities(Final report on WP 2)." Forschungszentrum Rossendorf, 2005. https://hzdr.qucosa.de/id/qucosa%3A21690.

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Анотація:
The goal of the work described in this report was the experimental investigation of the mixing of coolant with different quality (temperature, boron concentration) in nuclear reactors on the way from the cold leg through the downcomer and lower plenum to the core inlet in a systematic way. The obtained data were used for the clarification of the mixing mechanisms and form a data basis for the validation of computational fluid dynamics (CFD) codes. For these purposes, experiments on slug mixing have been performed at two test facilities, modelling different reactor types in scale 1:5, the Rossendorf and Vattenfall test facilities. The corresponding accident scenario is the start-up of first main coolant pump (MCP) after formation of a slug of lower borated water during the reflux-condenser mode phase of a small break loss of coolant accident (LOCA). The matrices for the experiments were elaborated on the basis of the key phenomena, being responsible for the coolant mixing during pump start-up. Slug mixing tests have also been performed at the VVER-1000 facility of EDO Gidropress to meet the specifics of this reactor type. The mixing of slugs of water of different quality is also very important for pre-stressed thermal shock (PTS) situations. In emergency core cooling (ECC) situations after a LOCA, cold ECC water is injected into the hot water in the cold leg and downcomer. Due to the large temperature differences, thermal shocks are induced at the reactor pressure vessel (RPV) wall. Temperature distributions near the wall and temperature gradients in time are important to be known for the assessment of thermal stresses. One of the important phenomena in connection with PTS is thermal stratification, a flow condition with a vertical temperature profile in a horizontal pipe. Due to the fluctuating character of the flow, this may cause thermal fatigue in the pipe. Besides of thermal fatigue, a single thermal shock can also be relevant for structural integrity, if it is large enough, especially in the case, that the brittle fracture temperature of the RPV material is reduced due to radiation embrittlement. Therefore, additional to the investigations of slug mixing during re-start of coolant circulation, the mixing of slugs or streams of water with higher density with the ambient fluid in the RPV was investigated. The aim of these investigations was to study the process of turbulent mixing under the influence of buoyancy forces caused by the temperature differences. Heat transfer to the wall and thermal conductivity in the wall material have not been considered. Experiments on density driven mixing were carried out at the Rossendorf and the Fortum PTS facilities.
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Kayhan, Bulent Abbas. "Prediction Of The Transient Force Subsequent To A Liquid Mass Impact On An Elbow Of An Initially Voided Line." Phd thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/12610489/index.pdf.

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The aim of the thesis, is to find the transient force applied by an individual transient liquid slug on an elbow at the end of a horizontal line due to an impact. The liquid slug is driven by pressurized air in a tank located upstream of the pipeline. The time dependent pressure distribution along the elbow and a vertical extension segment after the elbow was solved, with a 1-D numerical approach along a curved line mesh. For this purpose
firstly, a 3-D axial turbulent velocity profile function was assumed for the slug, with its shape allowed to sway towards the convex side of the elbow along the curved mesh with the aid of a calibration tool. Then, the pressure values were calculated by using 1-D application of Reynolds Equations in cylindrical polar and cartesian coordinates for the elbow and the vertical extension segment, respectively. The transient force acting on the elbow and the following vertical extension segment was found by using these calculated pressure values and applying conservation of momentum principle over the volume elements selected along the elbow and the vertical extension segment. For the analysis of the slug motion from the pressurizer tank to the elbow, a previously written computer code BOZKUS-2 was utilized. Then, the elbow and the vertical extension segment calculations in this study were made with a new code KAYHAN, which is an improved version of BOZKUS-2. The calculated transient force and impact pressures at the elbow were also compared with those from previous studies.
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Jordão, Haline Moura. "INTERVENÇÕES URBANAS EM ÁREAS DE POSSE EM GOIÂNIA." Pontifícia Universidade Católica de Goiás, 2013. http://localhost:8080/tede/handle/tede/2813.

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Made available in DSpace on 2016-08-10T10:49:56Z (GMT). No. of bitstreams: 1 PARTE 1 - HALINE MOURA JORDAO.pdf: 5886183 bytes, checksum: c1152a24406090bb6e88043f28d3cd0c (MD5) Previous issue date: 2013-03-25
Este trabalho tem como objeto de estudo as experiências de intervenções urbanas em áreas de posse realizadas no município de Goiânia no período de 1997 a 2012, com ênfase na área de posse do Jardim Goiás I. A análise engloba da gestão ao complexo processo de concepção e execução de projetos e obras de urbanização nessas áreas, demonstrando, por meio do relato das experiências realizadas no período citado, que é possível a proposição de diretrizes adequadas às especificidades e características físicas, socioeconômicas e culturais dos assentamentos, baseadas em parâmetros de qualidade que garantam intervenções que ampliem o acesso à moradia adequada e à integração da favela à cidade. No entanto, nem sempre as intervenções urbanas propostas atingem níveis satisfatórios de adequação. Para que os programas de urbanização, regularização e integração de assentamentos precários obtenham sucesso torna-se necessária uma gestão integrada entre as políticas habitacionais, sociais, econômicas e ambientais, com uma estratégia unificada para o desenvolvimento das cidades.
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6

Sen, Titash. "Deciphering Functions & Interactions of Fission Yeast Splicing Factor SpSlu7 Relevant to Constitutive & Alternative Splicing." Thesis, 2017. http://etd.iisc.ac.in/handle/2005/4130.

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The fission yeast genome with abundant multi-intronic transcripts, degenerate splice signals and presence of alternative splicing machinery is an attractive unicellular fungal model to investigate splice-site recognition and assemblymechanisms relevant to other fungal, worm, fly and higher eukaryotic genomes.Earlier work in the laboratory showed fission yeast SpSlu7 (homolog of budding yeast Slu7, Synergistic Lethal with U5-snRNA) has pre-catalytic intron context dependent splicing functions contrasting the predominant second step splicing role of budding yeast Slu7. Here we have investigated partners of SpSlu7 to discover its role splicing and other regulatory processes. Part I: Understanding SpSlu7 functional interactome by genetic and biochemical approaches We took up investigations todelineate the functional interactome of SpSlu7 that would mechanistically explain the pre-catalytic splicing arrest of spslu7-2 cells.Affinity purification of epitope tagged Slu7 associated complexes was donefollowed by mass spectrometry. The proteins associated with SpSlu7indicate its presence inboth pre-catalytic and second step spliceosomes. Genetic interaction assays were then carried out to validate and interpret these physical associations. Double mutants of slu7-2 with other splicing factor mutants, acting at distinct stages of the splicing pathway, were generated and studied. Taken together, we deduce an early pre-catalytic recruitment of SpSlu7 and a continued association afterthe first catalytic reaction. Further, in cells metabolically depleted of SpSlu7-2 the intron lariat intermediateRNA species was detected for intron 1 in transcript tfIID. This is a signature of poor second step splicing and thus demonstratesSpSlu7+functions improve second step splicing. Notably, other data from proteomic and genetic interaction studies showfunctional SpSlu7association with components of transcription, gene silencing and RNA decay machineries. Additionally the data uncovered a novel non-canonical Slu7function in meiotic RNA elimination in mitotically growing cells. In a parallel genetic screen for suppressorsof the cold sensitive slu7-2 therevertant UV10was obtained. Careful assessment of growth and cellular phenotypesconfirmed thatsuppression in UV10 was interactional and hinted an unanticipated effects on cellular pathways of mating and cell septation. Whole genome re-sequencing has been employed to identify candidate for the suppressor. Part II: Probing physiological relevance and mechanistic insights into SpSlu7 dependent fission yeast alternative splice events. The second part of the study probed possible physiological relevance and mechanistic insights of certain fission yeast exon skipping, intron retention and alternative splice site selection events and their dependence on SpSlu7. We identifiedstress and growth condition specific splice isoforms for certain transcripts.By assessment of the combinatorial effects of the intronic cis features, transcription elongation kinetics and splicing factor SpSlu7 activity, we deduced that suboptimal splice signals were the primary determinants of the low frequency usage of alternative splice sites. Additionally, we inferred use of certain alternative splice sites is co-transcriptional. Interestingly under conditions of mild thermal stress while SpSlu7 nuclear localization was unchanged, a distinct puncta like nuclear aggregation was noted foran interactor- branchpoint recognition protein U2AF59. These data underscorethe likelihood of stress-mediated remodelling of splicing factor complexes in fission yeast akin to higher eukaryotes.Overall, this study derived important insights on spliceosomal associations of splicing factor SpSlu7 and elucidated functions in splicing, meiotic RNA elimination, and stress-specific alternative splicing.
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Donat, Richard Walker. "Relationship between slug-test and effective hydraulic conductivities for 2-dimensional heterogeneous aquifers." 2008. http://etd.utk.edu/August2008MastersTheses/DonatRichardWalker.pdf.

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Книги з теми "Slu7-2"

1

Erik, Beckman. Nykomlingarna med en början och ett slut: Två olika saker, 2. [Stockholm]: Bonnier, 1992.

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Wei, Gina. Slut for You 2. Independently Published, 2019.

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Marchesa, La. SLUT 2 (bdsm, Bondage). Independently Published, 2019.

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nude69. Redhead Slut 2: Uncensored Pussies. Independently Published, 2017.

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Staff, Houghton Mifflin Company. Houghton Mifflin Reading Leveled Readers: Level 1. 2. 3 Lang Supp Slug and Bug. Houghton Mifflin Harcourt Publishing Company, 2003.

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Arx, Gabriella Baumann-von. Madame Lotti: Im Slum von Abidjan zählt nur die Liebe (Lotti Latrous 2) (German Edition). Wörterseh Verlag, 2011.

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Sourna, Neale. Neale Sourna's North Coast Academies' Diary, Volume 3, #1. 2_Laila - Daddy's Willing Little Slut: NCAD_v3n1. 2. PIE: Perception Is Everything, 2008.

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Hotel Bar Slut #1 and #2: Homewrecker Bartender Fucks a Married Man and Gets a Threesome Bukkake. Independently Published, 2017.

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Lee, Amy. Paperback Collection Sophie the Slut 1 and 2, High Class Hottie 1, a Letter Home about Jesse. Independently Published, 2018.

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Частини книг з теми "Slu7-2"

1

"2 SLUT: Shaming Sexual Activity." In Sexual Harassment Online, 23–52. Lynne Rienner Publishers, 2018. http://dx.doi.org/10.1515/9781626377035-003.

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"2. Slum Health: Research to Action." In Slum Health, 38–50. University of California Press, 2019. http://dx.doi.org/10.1525/9780520962798-007.

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"2. From the Catcall to the Slur: Recipients." In Everyday Violence, 51–78. Rutgers University Press, 2021. http://dx.doi.org/10.36019/9781978824034-004.

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Afsar, Rita, and Mahabub Hossain. "Rapid Urbanization and Population Changes in Dhaka City." In Dhaka's Changing Landscape, 31–68. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190121112.003.0002.

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Chapter 2 provides a brief overview of Dhaka’s demographic transition. It compares Dhaka with other mega cities across the world to understand its current challenges and potential to achieve prosperity and inclusivity. It shows a clear trend of decline in fertility for slum women and a demographic transition in Dhaka city. It analyses population changes in the communities over time, why and how these changes have occurred, and what trends are emerging in this process that need policy attention. These demographic trends and patterns are compared with the ward-level data from the 2011 Population and Housing Census, wherever it was available, to help readers understand population changes in the broader context. The question of decline in fertility for women in slum households, is examined with different hypotheses drawing on relevant theories related to the demographic transition and the demographic dividend. Accordingly, it analyses the factors contributing to the changes and outcomes.
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Khosrokhavar, Farhad. "Subcultures of Humiliation and Counter-Humiliation." In Jihadism in Europe, 33–104. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780197564967.003.0003.

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Chapter 2 discusses the fact that jihadism cannot be solely attributed to the disaffected young Muslims. A sizeable minority of jihadis consists of converts (from 8 percent to more than 20 percent, according to the European countries), as well as middle-class Muslims. Nevertheless, male disaffected Muslim youth, mostly from the first and the second generations, living chiefly in ghettoized neighborhoods, represent the major part of the jihadis in Europe. They come from at least three types of “slum subculture” which are marked by poverty, humiliation, and discontent. These are: the European slum subculture proper, the subculture of religious introversion (Salafism and Tabligh), and the subculture of violent religious confrontation (jihadism). These themes of poverty, humiliation, and discontent are discussed at length in this chapter and are reflected in interviews presented throughout, which were conducted by the author with some of the young men affected by these conditions. Also discussed are the ways in which secular society and its social freedoms contribute to the frustration and discontent expressed by these individuals.
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Vale, Lawrence J. "After Urban Renewal." In After the Projects, 41–65. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190624330.003.0002.

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Chapter 2 traces the changing nature of urban governance and participation between the 1940s and the present. It argues that much of HOPE VI variation is rooted in a city’s experience with earlier efforts at slum clearance, urban renewal, and central-city highways. In those cities where past backlashes against perceived excesses in land taking and displacement in residential areas led to lasting citywide movements to prevent this from happening again, there seems to be much greater protection for the poorest citizens under HOPE VI. Instead of more narrowly constructed urban regimes or growth machines focused in public-private partnerships, broader coalitions develop. Using the metaphor of constellations, the chapter identifies four types of poverty governance: the Big Developer, Publica Major, Nonprofitus, and Plebs. Each of these encompasses diverse players in development initiatives, but corresponds, respectively, to a polestar located in the private sector, public sector, not-for-profit sector, or community sector.
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Gransow, Bettina. "“Bewitched by the History Behind the Walls”." In The City in China, 17–40. Policy Press, 2019. http://dx.doi.org/10.1332/policypress/9781529205473.003.0002.

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This chapter examines how urban sociology in and of China is interconnected in historical and disciplinary terms with Robert Park and the Chicago School. It analyses four dimensions thereof: 1) personal relations between Robert Park and Chinese students and colleagues who enabled his visit to China, namely Xu Shilian, Wu Jingchao and Wu Wenzao; 2) institutional embeddedness of the sociology departments at both the University of Chicago and Yanjing University within the funding structures and strategies of the Rockefeller Foundation in the 1920s and 1930s and amongst competing approaches to research in (urban) sociology; 3) empirical fieldwork and comparative community studies in the form of Fei Xiaotong’s research on small towns in China (early 1980s) and his conceptualization of rural urbanization which built on his earlier classic rural community study and influenced official Chinese urbanization strategies until the recent National Plan on New Urbanization (2014-2020); and 4) theorizing China’s “villages in the city” (城中村‎) in light of previous debates inspired by the Chicago School on “cities within cities” (Park 2015), the “slum” and “urban villages”. Based on these four perspectives the chapter addresses questions of legacy, creative impetus and possible limitations arising from Park’s program vis-à-vis urban sociology in China today.
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Diwakar, Philip, Yuqing Liu, and Ismat ElJaouhari. "Evaluation of Flange Leakage due to Thermal Bowing and Shock." In Ageing and Life Extension of Offshore Facilities, 267–74. ASME, 2022. http://dx.doi.org/10.1115/1.885789_ch21.

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During a flaring event, some operating conditions in an LNG plant cause liquid refrigerant to be introduced into a flare header causing large temperature gradients between the bottom and top wall and lead to vertical and lateral displacements along with rotation of the horizontal header. This thermal bowing is a serious problem with risk of flange leakage due to differential thermal expansion between bolts and flange and pipe cracks at high stress concentration location as it lifts off the supports. This paper evaluates the introduction of warm gas into the flare header to prevent a flange leakage as a mitigation attempt. This paper recounts the use of Fluid Structure Interaction (FSI) to study bowing and flange leakage mitigation. The liquid flowing from the lateral into the main header pipe is multiphase in the dispersed, stratified, slug or annular flow régime. Multiphase flows with heat transfer are analyzed using Computational Fluid Dynamics (CFD) and conjugate heat transfer for steel. The temperatures on the metal are then transferred to a Finite Element Analysis (FEA) and analyzed for thermal stresses and deformation due to bowing. Elastic plastic Service Criteria Assessment per ASME BPVC Sec-VIII, Div.2 Part 5.2.4.3 (b) is performed to calculate Von-Mises, peak stresses and derive membrane and bending stresses on the hub, bolts, and gasket. These stresses are compared to ASME standard allowable limits. Based on these results, risk of flange leakage is evaluated, and mitigations are recommended to reduce the risk.
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"IPnad lm ex e r (P Darlomuegrh1t Sev United States, an 9d6t5hea ri n ty dI1n9d6e8x , aAnldl Crop Moisture et al. 1987). On the other hand, it is indeed ra e Yield Moistur eey In 1d9e8x4 ) ( Jionsetheetedv ro er uygyhetanr. oFttooreexxiasmtipnlea , pFo ig rt uiroen1o .5 f th il e lu ssetrcao te usnttrrieesfo in r al. 1991 hat in tiinve th ly enU ew ) in the Philip ni tienddeSxtatth es atisistpgia ne he iSnstiaanngndid elsew anrcdriezaesd in h g ere. Pr epcopAu ipit la re ri ltay ­ tdhreouU gh ntitiesdofSttean te g s, retahteerp th er acnen1t0agpeerarceeanta . f T fe hcu te s d , th beyI1n9d9e5x ) . (SPI), developed by McKee et al. (1993 ation governments of these larger countries are more drough Atisdiisncculsusd io ed nionfc se li v m er aatliccihnadpitceerssfionrtm hi osnvio to r a in ngdaec st caubsltio sh meedda to dealing with water shortages and have in Part III (Monitoring and e lume actively. For n sm ianlf le ra rsc tr ouucn tu tr riees, toitriesspmoonrde , l a ik lb el eyit th re a -t n lo igqiuceasl ) . inFdo ic reas , csoemepOalriid so ap noo ( f1s9 ev 8e5raarl ly p op wualranr in mge te te ocrh o­ ­ tuhseuael ntire coun ). scale ly anroem gi aoln ie asltrpyhm en aoymbeenaaff -e cttheedysrienscueltdrfo ro u m gh ltasrgae re -dur A at n io o n th . eDrrdoiusg ti hntgsuu is shuian ll gyrfeeqau tu ir reeaomfidnr im ou ugmhtof is t its that become es ta in b li asthm ed o sp ahnedr ic p er csiirsctulfaotr io n p er piaotdtse rn osftcoontthirneueemfoonr th msotnothbsecoormeyeeasrtsa . bl T is hheedmbaugt then cwaon mo Fnrtohms, sae as p o la nns, n o in r longer. drought impacts is closely related t nitude of teristics of drought ghapveerssp er eicotu iv sei , mtphle ic astp io a n ti s a . lNcahtairoancs ­ tohnesedtuorfattihoenporfectihpei ta etv io e n nt . shTohre ta g fi e o , tih ts eitn im te ing of the should know the probability that drought may simul­ dr ve-year ( n1s9i7 ty 9 , -a 8n3d ) r ta enge io onuss ly w a it f h fe in cttah ll eiorrbsoervdee ra rs l m an aj dordcervoep lo -p procdounctiinng ­ y th eiosusge ht in northeast Brazil is a good case in point. In gencies if such an event were to occur. Likewise, it is du arrisngirn ie tsh th oefcyleaas rs, 1979 and 1980 were both drought important for governments to know the chances of a sonal rain e fa lplritnocsiipcaslernasieny ( i s .e e . a , so a significant deficiency regional drought simultaneously affecting agricultura tals were slightl n y ) . a b In ov 1e9n8o1r , m th ael, sbeuat ­ pnreoad rb uyctn iv aittiyonisnotnhew ir hocm ou tnhte ry yaarsew de e p ll e n as deandtjafcoernftooodrltdhreo ug te hmt. po Irnal 19 d 8 is 2 tr , ib tuhtei on ra in re fa slul lte to d t al isnwaegrrei cu ble tu lo ral supplies. In some inst normal, but the temporal distribution of precipitatio wnfdrroomugnhetam rb i y ti gnaattiioonnss , tr iagtneagny ces, a nation’s primary was conducive to crop development. Agricultural drought may have signif o ic ri nmgatyhebel ik to e li ihmopoodrtthfaotodaw im e p re a ct fsow llo e w re e d le ss bya dv th er ese. mTohset se ant regional impa sefvoeurre ‘d drroouugghhtt ’ yyeeaa rs r w fo oord ld w su ipdpelioers . inLtihkeewpirs in e, citphaelgorcac in u -r e re xnpcoer ti onfgdnrco ts ugohntm (1 a9t8 ic 3 ) ago ri fcu th lt e u ra plre im vi poaucststw (M en atgya -f lih ve years, with dra­ such as occurred during the ENSO event of 1a9t8 ions, aes et al. 1988). (Glantz et al. 1987, Glantz e2-3 cha D ra rco te urg is httiscs. al T so hedair ffer in terms of their spatial nificantly alter a developing cou tnatlr . y’ 1s9a9c1c ) e , ssmtaoy fo si ogd ­ e sh viofltve fr ogm ra dsueaalsloyn , a to ndser as affect ea esgoino . nIsnoefdb lar m ge ayrxism ev uem re idnrt ought from donor governments. as Brazil, China, India, the Unit ceodunS tr tiaetse , e n su si cthy." In Droughts, 43–44. Routledge, 2016. http://dx.doi.org/10.4324/9781315830896-31.

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Тези доповідей конференцій з теми "Slu7-2"

1

Shon, Suwon, Siddhant Arora, Chyi-Jiunn Lin, Ankita Pasad, Felix Wu, Roshan S. Sharma, Wei-Lun Wu, Hung-yi Lee, Karen Livescu, and Shinji Watanabe. "SLUE Phase-2: A Benchmark Suite of Diverse Spoken Language Understanding Tasks." In Proceedings of the 61st Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers). Stroudsburg, PA, USA: Association for Computational Linguistics, 2023. http://dx.doi.org/10.18653/v1/2023.acl-long.496.

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2

Zhao, Bo, Christopher Sanabria, Terry Hon, and Alex Arayata. "A 2-Stage GaN IMFET Power Amplifier in an Embedded Heat Slug Laminate." In 2021 IEEE Radar Conference (RadarConf21). IEEE, 2021. http://dx.doi.org/10.1109/radarconf2147009.2021.9455303.

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3

Al-Lababidi, S., and M. L. Sanderson. "Non-Invasive Method for Velocity and Slug Length Measurements in Gas/Liquid Flow in Horizontal Pipes." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-82885.

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A method was developed for the measurement of slug frequency, slug velocity and slug length of two-phase gas/liquid flow under slug conditions in 2-inch horizontal pipe. The method consists of two pairs of ultrasonic transducers with 1MHz frequency. Non-invasive detection for slugs was achieved over a range of (0.1–1 ms−1) superficial liquid velocity and (0.1–3 ms−1) superficial gas velocity. The slug translational velocity was measured using a cross correlation technique for the modulated ultrasonic signals received. The slug length was measured after measuring the slug time t(slug) and slug translational velocity. The slug parameters measured were extensively compared with conductivity probes measurements and experimental correlations.
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4

Zhang, Hong-Quan, Qian Wang, Cem Sarica, and James P. Brill. "Unified Model for Gas-Liquid Pipe Flow Via Slug Dynamics: Part 2 — Model Validation." In ASME 2002 Engineering Technology Conference on Energy. ASMEDC, 2002. http://dx.doi.org/10.1115/etce2002/prod-29113.

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In Zhang et al. [1], a unified hydrodynamic model is developed for prediction of gas-liquid pipe flow behavior based on slug dynamics. In this study, the new model is validated with extensive experimental data acquired with different pipe diameters, inclination angles, fluid physical properties, gas-liquid flow rates and flow patterns. Good agreement is observed in every aspect of the two-phase pipe flow.
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5

Reinoso, Antonio, Luis E. Gomez, Shoubo Wang, Ram S. Mohan, Ovadia Shoham, and Gene Kouba. "Design and Performance of Slug Damper." In ASME 2007 26th International Conference on Offshore Mechanics and Arctic Engineering. ASMEDC, 2007. http://dx.doi.org/10.1115/omae2007-29387.

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A novel flow conditioning device, namely, the slug damper, which can be used upstream of compact separation systems, is investigated theoretically and experimentally. In the experimental part, a 3” ID slug damper facility has been installed in an existing 2” diameter two-phase flow loop. This flow loop includes an upstream slug generator, a Gas-Liquid Cylindrical Cyclone (GLCC©) attached to the slug damper downstream, and a set of conductance probes for measuring the propagation of the dissipated slug along the damper. Over 200 experimental runs were conducted with artificially generated inlet slugs of 50 ft length (Ls/d = 300) that were dumped into the loop upstream of the slug damper, varying the superficial liquid velocity from 0.5 to 2.5 ft/s and superficial gas velocity between 10 to 40 ft/ (in the 2” inlet pipe) and utilizing segmented orifice opening heights of 1”, 1.5”, 2” and 3”. For each experimental run, the measured data included: propagation of the liquid slug front in the damper, differential pressure across the segmented orifice, GLCC liquid level, GLCC outlet liquid flow and static pressure in the GLCC. The data prove that the slug damper is capable of dissipating long slugs, ensuring fairly constant liquid flow rate into the downstream GLCC. Also, the damper capacity to process large slugs is a strong function of the superficial gas velocity (and mixture velocity). The theoretical part includes the development of a mechanistic model for the prediction of the hydrodynamic flow behavior in the slug damper. The model enables the predictions of the outlet liquid flow rate and the available damping time, and in turn the prediction of the slug damper capacity. Comparison between the model predictions and the acquired data reveals an accuracy of 30% with respect to the available damping time and outlet liquid flow rate. The developed model can be used for design of slug damper units in the field.
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Zhu, Qianwei, Yilin Fan, Eduardo Pereyra, and Cem Sarica. "Flow Characteristics of Intermittent Flow in Inclined Pipes." In Offshore Technology Conference. OTC, 2023. http://dx.doi.org/10.4043/32633-ms.

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Abstract The importance of churn and pseudo-slug flow has been recognized, especially during recent years. Churn and pseudo-slug flow characteristics study in inclined pipes are still quite limited. An experimental study was conducted to investigate the inclination angle effect on slug to churn/pseudo-slug transition and the slug (Taylor Bubble) flow existence in large diameter pipes. The tests were conducted in a 0.1016-m ID pipe facility for inclination angles ranging from 2 to 90 degrees at 84-psia test section pressure. Tap water and compressed air were used as the test fluids. Wire-Mesh-Sensors (WMS) were used for flow characteristics measurement and visualizations.
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7

Yang, Jiede, Cem Sarica, Xuanzheng Chen, and James P. Brill. "A Study of Intermittent Flow in Downward Inclined Pipes." In ASME 1996 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/imece1996-0101.

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Abstract The downward simultaneous flow of gas and liquid is often encountered in hilly terrain pipelines and steam injection wells. Most of the available methods for predicting the behavior of gas-liquid flow in pipes have been developed for horizontal and upward inclined pipes. In this study, co-current steady state slug flow in downward inclined pipes is investigated, experimentally and theoretically. A series of slug flow experiments are conducted with an air-kerosene system in a 2-in. diameter, 75-ft long pipe installed on an inclinable structure. Liquid holdup and pressure drop measurements are obtained for downward inclination angles from 0° to −90° at different flow conditions. Correlations for slug flow characteristics are obtained based on the experimental data. A mechanistic model based on a unit cell approach has been proposed for the prediction of the detailed slug structure, and subsequently the pressure gradient. Fully developed slug flow could not be observed from −50° to −90°. A correlation was obtained for slug liquid holdup, and an analytical model and a correlation were developed for slug translational velocity. The lognormal distribution was found to best fit all the experimental slug length data. Equations for mean and design slug length were derived from the lognormal distribution function for inclination angles ranging from 0° to −30°. A slug frequency correlation was also developed. The model can be used to predict intermittent flow behavior in downward inclined pipes. The correlations for slug liquid holdup, slug translational velocity, and slug length and frequency are closure relationships applicable to any model. Slug frequency information is also imperative for erosion and corrosion rate predictions.
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8

Kang, Cheolho, and Parimal More. "Variation of Flow Regimes in +2 Degree Inclined Wet Gas Environments and Drag Reduction." In 2006 International Pipeline Conference. ASMEDC, 2006. http://dx.doi.org/10.1115/ipc2006-10367.

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Experiments were carried out to examine the study of flow patterns and the performance of drag reducing agents in a 40 m long, 10.16 cm diameter, + 2 degree inclined wet gas pipeline environments. Superficial liquid velocities ranging from 0.03 to 0.1 m/s and gas velocities from 2 to 10 m/s were investigated with the commercial DRA concentration of 0, 25 and 50 ppm. Light viscosity oil was used as the liquid phase and carbon dioxide was used as the gas phase. Variation of flow patterns in horizontal and +2 degree pipes are reported in this paper. The effect of inclinations on the pressure gradient is also presented. The stratified flow was dominant flow pattern in horizontal wet gas pipelines. However, for certain conditions, slug flow along with big wave forms was observed in 2 degree upward flow. The pressure gradient for 2 degree upward flow was higher than horizontal flow since the height of the liquid film was higher in case of upward flow. The pressure gradient decreased significantly as drag reducing agent was added in the pipeline. For slug flow in + 2 degree inclination, the pressure gradient reduction of 19 % was achieved for superficial liquid and gas velocities of 0.03 and 2 m/s at a flow improver concentration of 50 ppm. This was because the flow characteristics such as slug frequency and wave activity were changed with the addition of DRA.
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9

Zhang, Wei, and Jinliang Xu. "Multichannel Effect of Condensation Flow and Heat Transfer in Horizontally Positioned Silicon Microchannels With the Channel Depth Down to Thirty Microns." In ASME 2008 First International Conference on Micro/Nanoscale Heat Transfer. ASMEDC, 2008. http://dx.doi.org/10.1115/mnht2008-52315.

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Multichannel effect is an important issue in micro condensers. In the present paper, we fabricated a silicon chip, consisting of three rectangular microchannels, with each width of 800 microns but depth down to 30 microns. Saturated vapor of water enters the entrance of microchannels which were horizontally positioned. There are two types of flow patterns: (1) the annular flow at high inlet pressures; (2) the quasi-stable bubble slug in the microchannel upstream followed by the isolated bubbles downstream, at moderate or low inlet pressures. For the second flow pattern, the downstream isolated bubble is formed by breaking up: (1) the single vapor thread connecting the upstream bubble slug and the detaching bubble; (2) the dual vapor threads synchronously in the center microchannel; (3) the dual vapor threads non-synchronously in the side microchannels. The flow patterns in the two side channels are symmetry against the center microchannel. The upstream bubble slug is shorter in the side channels than in the center channel. The temperature gradient across the chip width direction accounts for the non-synchronously break-up of the dual vapor threads connecting the bubble slug and the detaching bubble, in the side channels, indicating the multichannel effects.
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10

Kang, C., and W. P. Jepson. "The Use of Flow Improvers to Decrease Pressure Drop in Multiphase Pipelines." In 2002 4th International Pipeline Conference. ASMEDC, 2002. http://dx.doi.org/10.1115/ipc2002-27353.

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Experiments were performed in a 10-cm diameter, 44 m long Plexiglas pipes, multiphase flow loop to examine the effect of flow improver in slug flow at inclinations of ±5degrees. Superficial liquid velocities between 0.5 and 1.5 m/s and superficial gas velocities between 2 and 6 m/s were studied. A 2.5 cP oil at 25 °C was used and water cut was 10%. The experiments were undertaken at a pressure of 0.13 MPa and a temperature of 25 °C with carbon dioxide as the gas. The effectiveness of flow improver on pressure drop and slug frequency was examined for concentrations ranging from 0 ppm to 50 ppm. The results showed that the flow improver was effective in reducing the pressure drop significantly at all superficial liquid and gas velocities. The flow improver concentration of 50 ppm was more effective than 25 ppm for all cases. At superficial gas velocities of less than 4 m/s and all liquid velocities with 50 ppm flow improver, the effectiveness of flow improver in upward flow was around 30%. At superficial liquid and gas velocities of 1.0 and 2 m/s with 50 ppm flow improver concentration, the effectiveness of up to 64% was achieved in downward flow. The slug frequency in both upward and downward flows decreased significantly in all cases with addition of flow improver. For example, at superficial liquid and gas velocities of 1.5 and 2 m/s, the slug frequency in downward flow decreased from 43 to 14 slugs/min. when 50 ppm of chemical was added. The flow pattern in downward flow was changed from slug flow to stratified flow at several velocities, which led to a large decrease in the pressure drop.
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Звіти організацій з теми "Slu7-2"

1

Zanoni, Wladimir, Paloma Acevedo, Giulia Zane, and Hugo Hernández. Discrimination Against Workers From Slums: What Is its Extent, What Explains It, and How Do We Tackle It? Inter-American Development Bank, March 2023. http://dx.doi.org/10.18235/0004799.

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Nearly 120 million people reside in urban slums in Latin America and the Caribbean, where precarious housing and socioeconomic circumstances testify to deep inequality. This paper investigates whether labor market discrimination influences the realities of fewer formal jobs and lower wages with which slum dwellers contend. We implemented a field experiment in Buenos Aires, Argentina, in which we hired human resource recruiters and tasked them with evaluating several pairs of similarly productive job applicants. Out of every 10 applicants, the recruiters chose slum dwellers 4.2 times and other applicants 5.8 times. They also evaluated slum dwellers as less fit for the vacancies and offered them lower wages (nearly 2 percent lower). An intervention showed recruiters the discrimination rate in Buenos Aires, after which they began favoring slum dwellers.
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2

Kiefner and Duffy. L51509 Two-Phase Flow in Horizontal and Inclined Pipes at Large Pipe Size and High Gas Density. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), February 1986. http://dx.doi.org/10.55274/r0010275.

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Knowledge of flow regime, holdup and pressure drop is needed in order to design gas and oil pipelines confidently and to minimize construction and operating costs. Previous public studies of two-phase flow in inclined pipes have used small diameter pipes two inches in diameter or less, and have primarily used air and water as the working fluids at low pressure (near one atmosphere). Present design methods are based upon the results of these experiments. In most advanced analyses available today, the flow regime transition is governed by a Froude number, the balance between inertial and buoyancy forces. The primary objective of the work has been to obtain experimental data to challenge the present two-phase flow analysis methods for large pipe size, high gas density, and pipe inclination. Present analysis and design methods for two-phase flow in pipelines are based on correlations of data from small pipes of order 2-inches diameter or less, for air-water flows at pressures near one atmosphere. To achieve this objective, Creare performed experiments in an existing test facility with a special test section assembled for this project. Pipe diameter and gas density are closer to prototypical oil and gas pipeline conditions than previous experiments reported in the literature. The key experimental results include flow regime observations, pressure drops, and holdup measurements. The instrumentation in the test facility allows detailed characteristics of the flow such as slug velocity, slug frequency, liquid film velocity, and slug length to be measured in the slug flow regime.
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3

Engard, Brett R., Carl D. McElwee, Rick Devlin, Brian Wachter, and Benjamin Ramaker. Hydraulic Tomography and High-Resolution Slug Testing to Determine Hydraulic Conductivity Distributions - Year 2. Fort Belvoir, VA: Defense Technical Information Center, December 2006. http://dx.doi.org/10.21236/ada478723.

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4

Nilsson, Hans, Magnus Appelberg, and Thomas Axenros. Provtagningsmetoder av akvatiska resurser med 3R i fokus. Institutionen för akvatiska resurser, Sveriges lantbruksuniversitet, 2023. http://dx.doi.org/10.54612/a.5o01b216ml.

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Flertalet av de övervakningsmetoder av fisk- och skaldjur som idag används globalt är dödande eller invasiva. Under 2020 hanterade SLU Aqua över 9 miljoner individer av fisk under fiskerioberoende provtagning. I Sverige, till skillnad från övriga Europa, räknas även de fiskar som fångas i provfiske till försöksdjur och regeringen har anmodat att myndigheter som använder försöksdjur bör upprätta strategier för sitt arbete med frågor som rör 3R, dvs. Replace (ersätta), Reduce (minska) och Refine (förfina). I syfte att undersöka möjligheterna att implementera 3R i SLU Aquas övervakning av fiskbestånd, redovisas i denna rapport möjliga metoder för att: Ersätta – Genom fiskeriberoende provtagning i syfte att ta fram förvaltningsunderlag för bedömning av beståndsstatus för Vänerns gösbestånd och kartlägga effekter av fiske på gös i Vänern (Kapitel 5) Minska – Genom studier av hydroakustisk frekvensrespons hos fisk och/eller användandet av trålmonterad stereovideo se på möjligen att reducera behovet av trålning under hydroakustiska trålundersökningar (Kapitel 2 och 3). Genom att komplettera nätprovfiske med hydroakustik, elfiske och eDNA reducera mängden dödad fisk i denna undersökningstyp (Kapitel 4). Förfina – Genom att kombinera olika metoder öka mängden kunskap varje provtagen individ ger samt hela ekosystem (Kapitel 3 och 4).
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5

Newcomer, Darrell R. 300 Area VOC Program Slug Test Characterization Results for Selected Test/Depth Intervals for Wells 399-2-5, 399-3-22, and 399-4-14. Office of Scientific and Technical Information (OSTI), March 2008. http://dx.doi.org/10.2172/926941.

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6

Naddafi, Rahmat, Göran Sundblad, Alfred Sandström, Lachlan Fetterplace, Jerker Vinterstare, Martin Ogonowski, and Nataliia Kulatska. Developing management goals and associated assessment methods for Sweden’s nationally managed fish stocks : a project synthesis. Department of Aquatic Resources, Swedish University of Agricultural Sciences, 2023. http://dx.doi.org/10.54612/a.31cfjep2i0.

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This report summarizes and synthesizes results from the Swedish Agency of Marine and Water Management (SwAM, or HaV) funded project “Förvaltningsmål för nationella arter (Management goals for nationally managed species)”. The objectives of the project have been to promote the development of management goals and associated status assessment methods and indicators, as well as reference points, for some nationally managed fish stocks both in coastal as well as freshwater areas. The report focusses largely on species and stocks that can be defined as data-poor. Such stocks are characterised by marked limitations in data availability and/or resources allocated to detailed analytical stock projections. Data-poor stocks also often lack carefully formulated management goals and associated methods and indicators for assessing stock status. In this report, we provide an overview of potential assessment methods and indicators and try to synthesise how they work and what the strengths and weaknesses are by applying them to selected data poor stocks such as pikeperch, pike, whitefish, and vendace. We also discuss how they relate to different potential management goals and provide recommendations for their application. We grouped the indicators and assessment methods by the three categories that are now used in the yearly status assessment framework provided by SLU Aqua (Resursöversikten/Fiskbarometern) – i) mortality, ii) abundance/biomass and iii) size/age structure. The results are also described for these three main categories of assessment indicators. Included is also a status report from a size- and age-based population dynamics model (Stock Synthesis 3) that is being developed for pikeperch in Lake Hjälmaren. An important experience from the project is that to improve the assessment methods for Swedish national fish stocks, it is important that managers develop both general as well as more detailed quantitative goals for the individual stocks. This should ideally be conducted in various forms of collaboration with the main stakeholders and scientists involved with assessment as participatory processes foster legitimacy. Carefully articulated management goals, which are possible to translate into quantitative targets, will facilitate the development of various approaches and methods to monitor stock statuses. Given the strong and complex interactions of fish and their environments it is also important to consider other pressures than fisheries when developing indicators and assessment methods. Our synthesis highlights a number of areas where the assessment of data-poor stocks can be improved: 1. Apply precautionary principles for data-limited stocks, particularly ones that are known to be vulnerable to exploitation. 2. Tailor approaches to how fisheries are managed in Sweden. Swedish nationally managed fish stocks are not managed by quotas (with one exception, vendace in the Bothnian Bay) and do not aim for maximum sustainable yield. Instead, the coastal and inland fisheries are managed by regulating the effort in the small-scale commercial fisheries (number of fishers/licenses and amount of gear). Regulation of recreational and subsistence fisheries effort, in terms of licenses or number of fishers) is not applied, nor possible since the fisheries is lacking obligatory notification and reporting systems. All national fisheries, however, are regulated by various technical measures (closed areas, size-limits, bag-limits, gear restrictions etc). Thus, goals and assessment methods that result in harvest limits or quota recommendations expressed in e.g. biomass/numbers are difficult to use as basis for management. Instead, there is a need for alternative management goals and associated assessment methods. 3. Use best practice methods and indicators and adapt as scientific knowledge is developed. Data-limited methods are developing rapidly, and new methods/approaches are proposed in the scientific literature every year. It is thus important to be updated on the most recent developments. 4. Clearly describe limitations/assumptions of methods used. It is important to be aware of and critically evaluate the assumptions underlying the analyses, and to carefully communicate uncertainty together with the stock status assessment. 5. Be particularly careful with low sample numbers. Many indicators and methods can be applied also on small sample sizes, however, the accuracy and precision of the estimates risk being low in such cases. 6. Accept that there is no "gold standard" for fisheries assessment. Each case study is unique and needs to be balanced against data availability, local needs and other important factors. This also means that analysts need to be careful when using generic reference levels or “borrowing” data from other stocks. 7. If possible, use several different methods/indicators. Although several indicators aim to measure similar aspects of the stock, small methodological differences can support the overall interpretation of individual indicator values. It is particularly important to incorporate many aspects and indicators (size/age/abundance/mortality) in order to produce a balanced assessment. 8. Develop means of communication. Indicators and goals should be easy to understand. However, interpretation of results from multi-indicator frameworks can be challenging. There is thus a need for finding ways of communication that can convey complicated results in a simple-to-understand manner. 9. For details on additional improvements, we refer the reader to the sub-header “recommendations for the future” found under each chapter. The implementation of Stock Synthesis for pikeperch in Lake Hjälmaren showed that it is possible to develop a more ambitious and detailed stock assessment model for a relatively data-poor stock. The model results partly support earlier interpretations of the development of the stock and the importance of the changes in regulations in 2001 (increased minimum size, increased mesh size and reduced mortality of undersized pikeperch). Before the model can be implemented and used for practical management, a number of actions for improvement are needed, which are highlighted in the relevant chapter. The most important next step is establishing management goals and reference levels for this stock. We recommend that such a dialogue is initiated by managers. The fisheries management goals should consider both biomass, fisheries mortality and size-based targets. To conclude, we stress the importance of improving all ongoing aspects related to the assessments of data-poor Swedish stocks. Strong local stocks and sustainable fisheries are vital for a variety of fisheries-related businesses and practices, particularly in rural areas, providing economical and societal value. Fishes also have important roles in aquatic food-webs and it is important that ecological values are managed wisely in order to reach targets for water quality, ecosystem structure and diversity. Given the strong and complex interactions of fish and their environments it is also important to consider other pressures than fisheries when developing indicators and assessment methods.
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7

Baseline survey results: Integrating adolescent livelihood activities within a reproductive health program for urban slum dwellers in India. Population Council, 2002. http://dx.doi.org/10.31899/rh2002.1007.

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The Population Council’s Frontiers in Reproductive Health Program and Policy Research Division, in collaboration with CARE India, is conducting an operations research study of an intervention designed to improve the lives and prospects of young women in several urban slum areas of Allahabad, Uttar Pradesh. The project aims to take a preexisting reproductive health program for adolescents and test the feasibility and impact of adding four additional components to it: 1) counseling about savings formation and livelihoods, 2) training in vocational skills, 3) assistance in opening savings accounts, and 4) follow-up support. CARE India is managing the larger adolescent reproductive health project, called the Action for Slum Dwellers’ Reproductive Health, Allahabad (ASRHA). Previous project updates have reported on the design and implementation of the study’s intervention and how it is integrated within the CARE ASRHA Project. This report presents key findings from the study’s baseline survey.
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