Дисертації з теми "Sleep outcomes"
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Caddas, Andrew. "Blue Light and Adult Sleep Outcomes." Otterbein University Distinction Theses / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=otbndist1620462993096741.
Повний текст джерелаCloonan, Yona Keich. "Sleep outcomes in children with craniofacial microsomia /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/10877.
Повний текст джерелаAltaf, Quratul-ain. "Sleep in patients with type 2 diabetes : the impact of sleep apnoea, sleep duration, and sleep quality on clinical outcomes." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8270/.
Повний текст джерелаImel, Janna L. "Positivity Ratio: Predicting Sleep Outcomes Across The Adult Lifespan." VCU Scholars Compass, 2016. http://scholarscompass.vcu.edu/etd/4604.
Повний текст джерелаJain, Sulabh. "Event-Driven Dynamic Query Model for Sleep Study Outcomes Research." Case Western Reserve University School of Graduate Studies / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=case1323377417.
Повний текст джерелаKoebke, Nicole C. "PHYSICAL ACTIVITY, SLEEP PATTERNS, AND HEALTH OUTCOMES IN UNIVERSITY LAW ENFORCEMENT OFFICERS." UKnowledge, 2012. http://uknowledge.uky.edu/khp_etds/6.
Повний текст джерелаAl-Rawashdeh, Sami. "Sleep Disturbance and Outcomes in Patients with Heart Failure and their Family Caregivers." UKnowledge, 2014. http://uknowledge.uky.edu/nursing_etds/11.
Повний текст джерелаAlghamdi, Amal. "The associations between poor sleep in pregnancy and obstetric, perinatal and neonatal outcomes." Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/18998/.
Повний текст джерелаReid, Morgan P. "Social Jetlag, Depressive Symptoms, and Longitudinal Outcomes in College Students." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5737.
Повний текст джерелаHoekema, Aarnoud. "Oral-appliance therapy in obstructive sleep apnea-hypopnea syndrome a clinical study on therapeutic outcomes /." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2007. http://irs.ub.rug.nl/ppn/300340222.
Повний текст джерелаSampasa, Kanyinga Hugues. "Sleep Duration, Sedentary Behaviour, Physical Activity, Depression, and Other Mental Health Outcomes Among Children and Adolescents." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/42304.
Повний текст джерелаPawl, Jean. "Sleep Loss and its Health Impact Among Family Caregivers of Persons with a Primary Malignant Brain Tumor." Digital Archive @ GSU, 2011. http://digitalarchive.gsu.edu/nursing_diss/25.
Повний текст джерелаRoane, Brandy Michelle. "Adolescent Insomnia as a Predictor of Early Adulthood Outcomes." Thesis, University of North Texas, 2006. https://digital.library.unt.edu/ark:/67531/metadc5399/.
Повний текст джерелаKüth, Simon. "Job Insecurity and its Association with Specific Health and Well-Being Outcomes." Thesis, Umeå universitet, Institutionen för psykologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-136035.
Повний текст джерелаWilliams, Kate Elizabeth. "Self-regulation from birth to age seven : associations with maternal mental health, parenting, and social, emotional and behavioural outcomes for children." Thesis, Queensland University of Technology, 2014. https://eprints.qut.edu.au/71568/1/Kate_Williams_Thesis.pdf.
Повний текст джерелаHense, Sabrina [Verfasser], Wolfgang [Akademischer Betreuer] Ahrens, and Gianvincenzo [Akademischer Betreuer] Barba. "Sleep duration and its role in the aetiology of cardio-metabolic health outcomes / Sabrina Hense. Gutachter: Wolfgang Ahrens ; Gianvincenzo Barba. Betreuer: Wolfgang Ahrens." Bremen : Staats- und Universitätsbibliothek Bremen, 2011. http://d-nb.info/107189790X/34.
Повний текст джерелаBoland, Elaine. "Sleep Disruption in Cognitive and Occupational Functioning in Bipolar Disorder." Diss., Temple University Libraries, 2014. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/283354.
Повний текст джерелаPh.D.
Bipolar Disorder is frequently associated with a number of poor outcomes including, but not limited to, a significant impairment in the ability to return to premorbid levels of occupational and psychosocial functioning, often despite the remission of mood symptoms. An extensive line of research has pointed toward deficits in cognitive functioning as playing an important role in this persistent disability, with a number of studies demonstrating the presence of numerous cognitive impairments during the inter-episode period. Also present during affective episodes as well as the inter-episode periods are reports of pervasive sleep disturbance. Sleep disturbance has been associated with the onset of manic episodes and is an oft-reported prodrome of illness onset. Despite the presence of deficits in these two domains of functioning during affective episodes as well as the inter-episode phase, there has been no evaluation of the degree to which these systems may interact to maintain such high rates of functional disability. The current study attempted to integrate these three separate lines of research to examine the role sleep disruption plays in both cognitive and occupational functioning in individuals with bipolar disorder. Seventy-two males and females with bipolar disorder in the euthymic phase (n=24), primary insomnia (n=24) or no psychological or medical diagnoses (n=24) completed a week of prospective assessment of sleep disruption via self-report and actigraphy. At the culmination of the sleep assessment period, all participants were administered a battery of neuropsychological tests of executive functioning, working memory, verbal learning, and attention. Additionally, participants completed self-reports of mood symptoms and current and lifetime occupational functioning. Results were mixed relative to hypotheses. Data supports persistent sleep disturbance among individuals with bipolar disorder when assessed via self-report, but no significant differences were observed compared to controls when assessed via actigraphy. Bipolar participants exhibited significantly poorer performance on measures of verbal learning and working memory, but no other cognitive deficits were observed relative to insomnia and control participants. Bipolar participants had a greater lifetime history of being fired compared to insomnia or control participants, and deficits in executive inhibition and switching were associated with increased lifetime firings across the sample. Sleep disturbance, either subjective or objective, failed to mediate this association. Findings are partially consistent with previous reports of persistent sleep disturbance and cognitive impairment among individuals with BD in the euthymic phase. More research should be conducted to better understand the underpinnings of functional impairment in BD.
Temple University--Theses
Kucharczyk, Erica. "The occupational impact of sleep quality." Thesis, Loughborough University, 2013. https://dspace.lboro.ac.uk/2134/11336.
Повний текст джерелаBarlow, Simcock Gail Mary-Rose. "Community sleep clinics run by health visitors : an evaluation of outcome." Thesis, University of Plymouth, 1997. http://hdl.handle.net/10026.1/1763.
Повний текст джерелаChamp-Rigot, Laure. "Nouvelles perspectives diagnostiques et thérapeutiques dans la prise en charge rythmologique des patients en situation d'insuffisance cardiaque Rationale and Design for a Monocentric Prospective Study: Sleep Apnea Diagnosis Using a Novel Pacemaker Algorithm and Link With Aldosterone Plasma Level in Patients Presenting With Diastolic Dysfunction (SAPAAD Study) Usefulness of sleep apnea monitoring by pacemaker sensor in elderly patients with diastolic dysfunction : the SAPAAD Study Clinical outcomes after primary prevention defibrillator implantation are better predicted when the left ventricular ejection fraction is assessed by magnetic resonance imaging Predictors of clinical outcomes after cardiac resynchronization therapy in patients ≥75 years of age: a retrospective cohort study Comparison between novel and standard high-density 3D electro-anatomical mapping systems for ablation of atrial tachycardia Safety and acute results of ultra-high density mapping to guide catheter ablation of atrial arrhythmias in heart failure patients Long-term clinical outcomes after catheter ablation of atrial arrhythmias guided by ultra-high density mapping system in heart failure patients." Thesis, Normandie, 2019. http://www.theses.fr/2019NORMC430.
Повний текст джерелаHeart failure is a major public health issue in developed countries, with a prevalence of 1-2% of global population, rising to 10% after 70 years of age. Therapeutic progresses have succeeded in improving patients’ prognosis, particularly in case of reduced left ventricular ejection fraction. Rhythm abnormalities are frequent, and need special consideration in case of heart failure. Meanwhile, there are still some gaps in the evidence: heart failure with preserved systolic function is complex and difficult to treat, primary prevention of sudden cardiac death is effective but there is a need to better select candidates, whether elderly patients should be treated as younger individuals, and finally how to improve outcomes of atrial fibrillation catheter ablation. Firstly, we have conducted a prospective study to evaluate the Sleep Apnea Monitoring algorithm provided in a novel pacemaker in patients with diastolic dysfunction. Besides, we analyzed whether magnetic resonance imaging could predict cardiac outcomes in patients with an implantable cardioverter defibrillator better than echocardiography. We also reported the outcomes of the cardiac resynchronization therapy in patients ≥75 years old compared to younger patients. Finally, we studied the results of a novel ultra-high density mapping system to guide ablation procedures of complex atrial arrhythmias in heart failure patients compared to controls
Wall, Ann-Marie. "The influence of maternal attributions and personality on recommendations of, and outcome expectancies, for infant sleep interventions." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2899/.
Повний текст джерелаMok, Yuk-wan Wendy. "A validation of the Calgary Sleep Apnea quality of life index (Chinese version) and an evaluation of treatment effectiveness and patient perference by physiological and neurobehavioural outcome measures in Chinese sleep apnea patients /." Hong Kong : University of Hong Kong, 2002. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2520564x.
Повний текст джерела莫玉雲 and Yuk-wan Wendy Mok. "A validation of the Calgary Sleep Apnea quality of life index (Chineseversion) and an evaluation of treatment effectiveness and patientperference by physiological and neurobehavioural outcome measures inChinese sleep apnea patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2002. http://hub.hku.hk/bib/B3122653X.
Повний текст джерелаMilioti, Styliani G. "Long-term neuromotor outcome in full term infants with prolonged central sleep apnoeas : a follow-up study until puberty." Thesis, Brunel University, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.445920.
Повний текст джерелаHsu, C. Y. "The impact of obstructive sleep apnoea/hypopnoea and its treatment with continuous positive airway pressure on the outcome of stroke." Thesis, University of Edinburgh, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.652659.
Повний текст джерелаGuimarães, Kátia Cristina Carmello. "Efeitos dos exercícios orofaríngeos em pacientes com apnéia obstrutiva do sono moderada: estudo controlado e randomizado." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-22082008-170703/.
Повний текст джерелаIntroduction: Obstructive sleep apnea is a public health problem due to the high prevalence and high morbidity. Continuous positive airway pressure (CPAP) is the treatment of choice for severe cases. However, adherence to CPAP is variable among moderate obstructive sleep apnea patients and alternative treatments are necessary. Upper airway muscle weakness plays an important role in the genesis of obstructive sleep apnea. Oropharyngeal exercises (myofunctional therapy) are derived from phonoaudiological therapy within orofacial motricity specialty, and were developed for the treatment of sleep obstructive apnea. The myofunctional therapy consists of isometric and isotonic exercises directed to tongue, soft palate and lateral pharyngeal wall, including adequate functioning of suction, swallowing, chewing, breathing and speech. Objective: To test the hypothesis that myofunctional therapy will attenuate obstructive sleep apnea syndrome severity. Methods: We included 37 moderate obstructive sleep apnea patients apnea-hypopnea index (AHI) between 15 and 30 events/hour that were randomized to 3 months of general measures, including nasal lavage, orientation of alternated bilateral chewing and exercises of inspiration and expiration in the seated position (control group). The treatment with myofunctional therapy consisted of oropharyngeal exercises performed without supervision daily and under supervision once a week (20 minutes), in adition to the orientations given to the control group. Anthropometric measurements, questionnaires evaluating snoring frequency and intensity (Berlin), daytime subjective sleepiness (Epworth), sleep quality (Pittsburgh) and full polysomnography were performed at baseline and in the end of the study. Results: 45 patients were included in the study, 8 were excluded because they failed to return regularly. The final group consisted of 37 patients age (mean ± SD) = 51±9 years, body mass index = 30±4 Kg/m2 and apnea hypopnea index = 23±5 apneas/hour), seventeen were randomized to the control group and twenty to the treatment group. The control group did not changes in all parameters along the study. In contrast, the patients treated with myofunctional therapy presented a significant decrease (p<0.05) in neck circumference (39.5±3.4 vs. 38.3±3.7 cm), daytime somnolence (13.2±5.4 vs. 8.2±6.0), sleep quality (10.3±3.5 vs. 7.1±2.3), snoring frequency (3.9±0.5 vs. 2.7±1.1), snoring intensity (3.4±0.5 vs. 1.8±0.9) and apnea hypopnea index (23.2±4.8 vs. 14.6±8.1 events/hour; p<0.01). Considering the entire group, changes in neck circumference correlated with the changes in AHI (r=0.55; p <0.001). Conclusions: Myofunctional therapy, over 3 months, reduce symptons and severity of moderate obstructive sleep apnea. The improvement correlates with the decrease of cervical diameter, suggesting that the musculature tonus of upper airway while awake correlates with the severity of obstructive sleep apnea and can be modified with myofunctional therapy.
Ieto, Vanessa. "Efeitos da terapia miofuncional orofacial sobre o ronco e a qualidade de sono em pacientes com ronco primário e apneia obstrutiva do sono leve a moderada." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-01122014-112917/.
Повний текст джерелаSnoring is generated by pharyngeal obstruction and vibration during sleep. Snoring is extremely common and may cause severe social problems and may indicate obstructive sleep apnea (OSA). However, there are no standardized methods for measuring snoring and the treatment of primary snoring or snoring associated with mild forms of OSA is controversial. Orofacial Myofunctional Therapy consists of isometric and isotonic exercises directed to tongue and soft palate for the treatment of moderated OSA. However, the effects of Orofacial Myofunctional Therapy on snoring were not objectively measured. OBJECTIVES: Primary: to determine the efficiency of Orofacial Myofunctional Therapy in reducing snoring of patients with primary snoring, mild and moderated OSA. Secondary: to develop a methodology to objectively quantify snoring; to assess the relation of snoring characteristics with OSA severity; to assess the effect of Orofacial Myofunctional Therapy upon the perception of snoring and sleep quality of the bed partner. METHODS: We included patients of both genders aged between 20 to 65 years old with polissomnographyc diagnoses of primary snoring, mild or moderated OSA. Patients were randomized for treatment with Orofacial Myofunctional Therapy or Control (use of nasal dilator strips and respiratory exercises) for 3 months. All patients were evaluated at the beginning and end of the study by questionnaires (Epworth, Pittsburgh), orofacial motricity assessment and complete polysomnography with the register of snoring. Bed partners assessed snoring and their own sleep quality (Pittsburgh). RESULTS: Thirty nine patients aged (mean ± standard deviation) =46 ± 13 yeas old and body mass index (BMI) (mean ± standard deviation) = 28,2 ± 3,1 Kg/m2, apnea hypopnea index (AHI)= 15,3 ± 9,3 events/hour, being 6 patients with primary snoring, 17 with mild OSA and 16 with moderated OSA completed the study. No significant change occurred in the Control Group in all variables. In contrast, patients treated with Orofacial Myofunctional Therapy presented (as compared to baseline) a significant decrease (p < 0.05) in neck circumference (38,0 [36,4-39,5] vs. 37,5 [36,0-39,0] cm), Orofacial Motricity Assessment (37,0 [23,0-42,0] vs. 19 [13,0-24,0]), Snoring Index (99,5 [49,6-221,3] vs. 48,2 [25,5-219,2]) and Total Snoring (60,4 [21,8-220,6] vs. 31,0 [10,1-146,5]). Bed partners of patients treated with Orofacial Myofunctional Therapy (n=13) reported a significant improvement in the perceived intensity (4,0 [2,5-4,0]) vs. 1,0 [1,0-2,0]) and snoring frequency (4,0 [3,0-4,0] vs. 2,0 [1,5-3,0]). Sleep quality of bed partners also improved but did not reach statistical significance (p=0.0618). Snoring Index and Total Snoring at basal and after 3 months presented a moderated correlation to OSA severity, measured by AHI (r between 0,505 to 0,603). CONCLUSIONS: Orofacial Myofunctional Therapy for 3 months is effective in reducing objectively measured snoring frequency and intensity. Orofacial Myofunctional Therapy can be effective for a great number of the population who present primary snoring or mild OSA forms
Yagihara, Fabiana Tokie. "Beauty CPAP: o impacto do tratamento da apneia obstrutiva do sono com aparelho de pressão aérea contínua sobre a percepção da idade e da aparência saudável, descansada e atraente num estudo prospectivo, randomizado, cruzado e placebo controlado." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-06092017-134606/.
Повний текст джерелаObjectives: To compare the effects of one month with continuous positive airway pressure (CPAP) treatment and placebo intervention on the appearance and objective facial skin characteristics of patients with obstructive sleep apnea (OSA) in a randomized crossover study. Methods: Consecutive sleepy patients with severe OSA were included. The patients underwent three polysomnograms (PSG): first one to confirm OSA and two additional ones using placebo (nasal dilator) and for CPAP titration before starting each treatment period. All patients were randomly included into two treatment groups: 1) placebo use and 2) CPAP use. After one month with the first treatment and 15 days of washout, patients were crossed-over for the second treatment. Photographs from the patients\' faces were obtained in the three experimental moments. The photographs were presented in a random order by the Qualtrics Survey Software, and were evaluated online by 704 observers for quantifying healthy appearance (unhealthy to extremely healthy), attractive (unattractive to extremely attractive) and tired (not tired to extremely tired). Apparent age was also rated for each observer. Quantitative evaluations of the skin characteristics of the patients\' faces were also carried out at each experimental moment, including the presence of acne, patches, porosity, wrinkles, texture, and skin tone uniformity, through the capture of images by VISIATM System equipment. Results: 30 patients (age = 46±9 years, 21 men) were evaluated. During treatment period, the patients wearing placebo intervention on 98% of the nights and adherence to CPAP was 94%, with a mean of 6.0 ± 1.7 hours of use per day of treatment. After CPAP treatment, compared to baseline and after placebo treatment, improvement in the objective sleep quality, sleepiness, quality of life and depressive symptoms were observed (P <0.05). Observational assessment of the photographs showed that patients were evaluated as being younger after using CPAP (P < 0.001), but no quantitative changes in face skin characteristics were observed compared to the baseline and after the use of placebo. Linear regression analysis identified the number of days with CPAP treatment, total sleep time and percentage of total sleep time with oxyhemoglobin saturation below 90% were predictors of decreasing of rated age after CPAP treatment. Conclusion: Sleepy patients with severe OSA had a younger appearance after one month of CPAP treatment
Kayamori, Fabiane. "Efeitos da terapia miofuncional orofacial em pacientes com ronco primário e apneia obstrutiva do sono na anatomia e função da via aérea." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5150/tde-05012016-153030/.
Повний текст джерелаINTRODUCTION: Obstructive sleep apnea (OSA) is a public health problem, with high prevalence and severe consequences. The gold standard treatment for severe OSA is the application of continuous positive airway pressure (CPAP) during sleep. However, adherence to CPAP is low, especially in patients with primary snore and mild OSA. A previous study from our laboratory demonstrated that oropharyngeal exercises are effective in patients with moderate OSA (Guimaraes et. al, AJRCCM 2009:(179);962-966). Nonetheless, in this first study the number of patients included in the randomized trial was relatively small (n=31) and evaluated only patients with moderate OSA. Moreover, the number of oropharyngeal exercises the patients had to do 3 times a day was large (n=10) and raised doubt about the compliance to treatment, and the mechanism by which the therapy was effective was not elucidated. OBJECTIVE: The primary objective was to evaluate the effectiveness to reduce OSA severity of a short program of oropharyngeal exercises (6 exercises) in patients with primary snore, mild, moderate and severe OSA. The secondary objective was to evaluate the impact of reduced oropharyngeal exercises program on apnea hypopnea index (AHI) in patients stratified by baseline AHI, the anatomy of upper airway by magnetic resonance (MR), strength and fatigue of the tongue and critical closing pressure (Pcrit). METHODOLOGY: Patients of both sexes, with age between 20 and 65 years old, recently diagnosed with primary snore, mild, moderate or severe OSA who refused to use CPAP were included. Patients with body mass index (BMI) >= 35kg/m2, craniofacial deformities, edentulous, regular use of hypnotic medication, severe nasal obstruction, patients undergoing other treatments for OSA and patients with unavailability to comply with the protocol were excluded. The patients were evaluated at the beginning and end of the study by questionnaire of daytime sleepiness (Epworth, ranging from 0 to 24 points), quality of sleep (Pittsburgh, ranging from 0 to 21 points), oral myofunctional evaluation for OSA (ranging from 0 to 20 points), MR of the upper airway, tongue strength and fatigue, critical closing pressure (Pcrit) and polysomnography. The patients were randomized to 3 months of oropharyngeal exercises (6 exercises) or Control (use of nasal dilator strip and respiratory non specific respiratory exercises). All patients were instructed to perform the exercises 3 times a day and evaluated by a speech pathologist once a week. The primary endpoints were evaluated primarily by two-way repeated-measures ANOVA. A paired t test was also used as a secondary evaluation. RESULTS: A total of 251 patients were evaluated and 60 patients were randomized. The 2 groups (n=30) were similar at study entry for all the parameters and 58 patients completed the study (58.6% males, age: 45.9±12.2 years, BMI: 28.8±4.3 kg/m2, AHI=18.4±12.6 events/h and minimum saturation84.9±6.4%). All variables remained unchanged in the Control group. There were no changes in Epworth and Pittsburgh questionnaires as well as BMI in patients randomized to oropharyngeal exercises. As compared to study entry, there was a significantly reduction on neck circumference (38.8 ± 3.3 vs 38.4±4.4cm), arousals index (21.3 ± 10.9 vs 16.9 ± 7.9 arousals/h), AHI (19.5 ± 14.2 vs 15 ± 10.2 events/h), oral myofunctional evaluation for OSA (9.3 ± 2.9 vs 3.6 ± 2.4) in the patients randomized for oropharyngeal exercises. Oropharyngeal exercises only reduced AHI significantly among patients with moderate OSA (23.8 ± 5.2 vs 17.7 ± 5.2) and severe OSA (43.9 ± 19.5 vs 24.7 ± 21.4) at study entry. No significantly changes as evaluated by two-way repeated-measures ANOVA were observed on upper airway MR anatomy (10 Control and 14 oropharyngeal exercises), tongue force and fatigue (19 Control and 19 oropharyngeal exercises) and Pcrit (7 Control and 10 oropharyngeal exercises). As compared to study entry there was a significant reduction as evaluated by paired T test on tongue volume (p=0.031), tongue fat (p=0.008) and a significant increase of tongue strength (p=0.046) of patients randomized to oropharyngeal exercises. CONCLUSION: A short program of oropharyngeal exercises is effective to reduce OSA severity in patients with moderate and severe OSA. The trend to increase tongue strength and reduce tongue fat may explain the beneficial effects of oropharyngeal exercises
Chatrathi, Meenakshi. "The effects of sleep duration and sleep quality on health outcomes in the Marshallese population in Northwest Arkansas." Thesis, 2020. https://hdl.handle.net/2144/41210.
Повний текст джерелаMoleus, Philippe Stuart. "Determining treatment outcomes of traumatic brain injury." Thesis, 2018. https://hdl.handle.net/2144/31264.
Повний текст джерелаLabrosciano, Clementine. "Readmissions in Australian Patients with Cardiovascular Disease." Thesis, 2019. http://hdl.handle.net/2440/123508.
Повний текст джерелаThesis (Ph.D.) -- University of Adelaide, Adelaide Medical School, 2019
Lai, Yin-Chieh, and 賴穎婕. "Clinical Outcomes and Genetic Contribution in Mood Disorders: The Role of Sleep Features." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/52694793795430211132.
Повний текст джерела國立臺灣大學
流行病學與預防醫學研究所
103
Sleep problems are commonly observed in mood disorder patients, the sleep profiles among subgroups (major depressive (MDD), bipolar disorder (BD) patients, their relatives, and controls) and the familiality of sleep problems in MDD and BD families have not been well known. Sleep disturbance is important because it impairs quality of life (QOL), contributes to relapse, and has adverse consequences. Moreover, less is known about the longitudinal time effect between sleep and mood change. Sleep disturbance has caused by abnormal circadian function in mood disorders. Several genes that are involved in the regulation of circadian rhythms implicated in the susceptibility to mood disorders and sleep related problems. This suggests a connection between proper mood regulation and a normal functioning circadian clock. While sleep disturbance and circadian dysregulation are critical pathophysiological elements in mood disorders, many questions about the sleep profiles and the mechanisms remain. The current study aimed to explore the role of sleep in clinical outcomes and genetic contribution in mood disorders. First, we compare the sleep disturbances among subgroups and evaluated familiality in MDD and BD families. We examined the associations of sleep quality and patients’ QOL and functional impairment. Second, we evaluated the time effects of sleep and mood, and whether poor sleepers predict poorer clinical outcomes at follow up period. Third, we investigated the relationships between genetic variants in circadian genes with BD and with sleep phenotypes in the Han Chinese population. We recruited around ~1300 participants, including around ~700 probands ( ~350 DSM-IV diagnosed BD-I, 150 BD-II, and 200 MDD), 618 relatives and 235 healthy controls were completed structural diagnostic interview, sleep measurements including Pittsburgh Sleep Quality Index (PSQI), and Mornigness-Eveningness scale (M/E scale); the severity of symptoms measurements including Beck Depression Inventory (BDI-II), and Young Mania Rating Scale (YMRS); and World Health Organization Quality of Life brief version (WHOQOL) questionnaires. Single nucleotide polymorphisms in the circadian genes were genotyped using Affymetrix Genome-Wide CHB Array. Familiality of components of sleep was evaluated using mixed regression models and intraclass correlation coefficients (ICC). The relation of sleep on symptom severity and impairments during the same interval longitudinally across the 6-month period was also examining by mixed regression models. Genetic association analyses were performed using PLINK software. Three-quarter of mood disorder patients divided to “poor sleepers”, and with worse QOL and more functional impairment (p<0.01) than good sleepers. MDD patients had significantly worse sleep quality than BD patients, whereas there was no difference between unaffected relatives and controls. Moderate familial aggregation observed in subjective sleep quality, sleep latency and disturbance. Sleep disturbances such as poor sleep quality and nightmares increased the risk for suicidal ideation and suicide attempts. After a six month follow up, the persistence rates of sleep disturbance were 77.8% and 82.60% in BD and MDD, respectively. Multivariate analyses in linear/logistic regression models revealed that sleep disturbances at baseline including global score and frequent nightmares were significantly increased the consequence of depression (OR=1.07-4.56), suicide ideation (OR= 1.25-3.35) and suicide plan (OR= 1.20-6.21). A longitudinal relationship was showed of global score with poor clinical outcomes expect mania during the follow up. Our data suggested the idea that chronotypes have an impact on depressive features, with higher severity of depressive and suicide ideation for the eveningness type. For genetic association analysis, there were five genes (ARNTL2, BHLHE41, CNR1, RORA, RORB) showed significant with BD. Our results support for the involvement of RORs family in the risk of developing BD. For sleep phenotypes, we found ARNTL, ARNTL2, CNR1, CRY1, CSNK1E, CSNK2A1, GSK3b, NPAS2, PER3, RORA, RORB, TIMELESS, TIPIN genes with positive associations. Due to the notable sleep problems in mood disorders and the patients with sleep disturbances heightened the risk of recurrence and suicidality was demonstrated in the study. The special sleep intervention in mood disorders is required in clinical settings. The genes in circadian pathway may be an important candidate. Further replication studies are needed to investigate the functional properties of the genes in studying the pathogenesis of mood disorders and sleep problems.
Lee, Shuo-Fang, and 李碩芳. "The effect of residential insecticide exposure and sleep disturbance during pregnancy on birth outcomes." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/852zum.
Повний текст джерела慈濟大學
公共衛生學系碩士班
104
Abstract Background: Pyrethroids and organophosphate insecticides are commonly used in residential environment. Previous studies revealed that organophosphate insecticides have negative effects on infant birth outcomes and neurobehavioral development, but few studies focused on pyrethroids. According to the report from National Sleep Foundation, 79% of the pregnant women has changes in sleeping habits. Furthermore, 25% of the pregnant women has sleep disturbance in second trimester; and the percentage increased to 75% in third trimester. There are studies investigating the associations between sleep disturbance and preterm birth and low birth weight, however, inconsistent results were reported. Therefore, the objective of this study is to explore the effects of residential insecticide exposure and sleep disturbance during pregnancy on birth outcomes. Materials and Methods: This study is a prospective birth cohort study initiated from October 2013 to June 2016. Pregnant women were recruited from the department of obstetrics and gynecology in a medical center in east Taiwan. In second trimester (25 weeks), we used a structural questionnaire to collect the information of insecticide using habits, types, formulations, and frequencies before and during pregnancy. Additionally, we used the Pittsburgh Sleep Quality Index to measure the sleep characteristics such as sleep duration and quality. The birth outcomes including birth weight, length, head circumference, and chest circumference were obtained from medical records. Independent t-test and chi-square test were used to analyze the associations between demographic variables and exposure variables. Multiple linear regressions were used to explore the synergic effects of residential insecticide exposure and sleep disturbance during pregnancy on birth outcomes with adjusted maternal age, parity, pre-pregnancy BMI, education, passive smoking and newborn sex. Besides, we applied land use survey data to calculate the percentage of the agriculture area in different buffer zones as the proxy of pesticides exposure. Results: We found residential mosquito coil use during pregnancy may decrease chest circumference 0.791± 0.414 cm (0.05
"Childhood sleep/wake patterns: local norms, associations, health outcomes and interventions = 兒童睡眠節律 : 正常參考值, 相關因素, 對健康的影響, 和幹預改善". 2014. http://repository.lib.cuhk.edu.hk/en/item/cuhk-1291272.
Повний текст джерелаThesis Ph.D. Chinese University of Hong Kong 2014.
Includes bibliographical references (leaves 188-207).
Abstracts also in Chinese; appendixes in Chinese.
Title from PDF title page (viewed on 14, September, 2016).
Yu, Xinting.
Quinn, Melanie. "Psychosocial Outcomes and Predictors of Distress Among Military Spouses." Thesis, 2017. https://vuir.vu.edu.au/35043/.
Повний текст джерелаKuo, Wen-Yu, and 郭玟佑. "Relationship Between Post-Operative Sleep Hours and Physical Activity Level and Health Outcomes of Hip Fracture Elders With Diabetes." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/22440454695152910756.
Повний текст джерела長庚大學
護理學系
102
Purpose:The purpose of this study was to explore the post-operative changes of sleep hours and physical activity level and their correlation between physical functional recovery, muscular strength of the affected side, quality of life, self-rated health, and blood sugar control for hip fractured elders with diabetes. Research Design and Methods:This study was a secondary analysis of data on 36 community-dwelling elders with hip fracture and diabetes who were 60 years or older from a prior longitudinal study. SenseWear armband (BodyMedia, Inc., USA) was used to record sleeping hours and physical activity level. Hand-held dynamometer was used to examine muscular strength of the affected side. One Touch machine was used to examine the blood sugar. Other measures include Chinese Barthel Index, Lawton’s Instrumental Activities of Daily Living Scale, Short Form-36 Taiwan version and EQ-VAS visual analog scale. Data were analyzed by the generalized estimating equations approach to examine correlation between longitudinal changes of sleep hours and physical activity level and hip fractured elders’ health outcomes during the first 6 months after hospital discharge. Results:We found that hip fractured elders with diabetes who did not have normal sleep hours had poorer outcomes in self-care ability of medication management, muscular strength of the affected side, and blood sugar control (post cibum, after meals;ante cibum, before meals) than those who had normal sleep hours. However, there were no statistically significant differences between two sleep type groups in quality of life and self-rated health during the first 6 months after postsurgical discharge. We also found that better physical activity level of the patients during the first 6 month following discharge was associated with better health outcomes especially in ADL performances, transfer ability, walking ability, and overall IADL ability to use telephone, ability to do laundry, ability to handle finances, muscular strength of the affected side and general health perceptions. However, there were no significant relationships between physical activity level and self-rated health, blood sugar control.Considering both sleep hours and physical activity level , we found that did not have normal sleep hours also had poorer outcomes in self-care ability of medication management, muscular strength of the affected side, and blood sugar control (post cibum, after meals;ante cibum, before meals) than those who had normal sleep hours. Better physical activity level was associated with better ADL performances, transfer ability, walking ability, and overall IADL ability to use telephone, ability to do laundry, ability to handle finances, muscular strength of the affected side. Based on this study, more attention needs to be paid to the consistent sleep hours and activities of hip fractured older persons with diabetes during the first 6 months following the surgery, in order to improve their self-care ability, muscular strength, quality of life and blood sugar control.
Tsai, Ming-Show, and 蔡名秀. "The Effects of Sleep Quality, Depressive Symptoms, and Physical Activities on Pregnancy Outcomes among Pregnant Women in Their Third Trimester." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/56117168104029475799.
Повний текст джерела國立陽明大學
臨床護理研究所
94
The purposes of this research were to examine the effects of sleep quality, depressive symptoms, and physical activities on pregnancy outcomes among pregnant women in their third trimester. With prospective and descriptive correlational design, the subjects of this research were 220 pregnant women in their third trimester. At antepartum outpatient clinics, a face-to-face interview with structured questionnaires was conducted toward the subjects. The study variables included socio-demographic characteristics, sleep quality, depressive symptoms, and physical activities. The data was analyzed by descriptive statistics, t-test, one way ANOVA, chi-square, pearson correlation and logistic regression. The results showed: (1)Most of women in the research had positive pregnancy outcomes. Non-plan cesarean section and vacuum vaginal delivery only took 8.7% and 20.2% respectively. The rate of preterm birth and low birth weight were 3.2% and 4.1% respectively. Average gestational age of newborn was 39.03±1.30 weeks. Average birth weight was 3177 ± 424 grams.(2)79.5% pregnant women had poor sleep quality problems. The main problem was sleep disturbance.(3)34.5% of research subjects had serious depressive symptoms. The most severe of all was somatic complaints.(4)The research subjects had nearly the same energy expenditure on record of ordinary days, holidays, and 3 days. They were 38.54 kcal/kg/day、38.58 kcal/kg/day、38.56 kcal/kg/ day respectively. The main moderate-to-vigorous physical activities of pregnant women were strolling, shopping, and climbing stairs.(5)The sleep quality and depressive symptoms of the research subjects were positively correlated, which indicated that the better the sleep quality, the less the depressive symptoms. No significant correlations are found between sleep quality and depressive symptoms, and the amount of physical activities on ordinary days, holidays, and the 3 days. However, negative correlations were evident in moderate-to-vigorous physical activities on holidays and the 3 days. That indicated pregnant women need a certain amount of energy expenditure in moderate-to-vigorous physical activities to improve sleep quality and reduce depressive symptoms.(6)Examined factors related to non-plan cesarean section, the results revealed that primipara, poor sleep quality, and low physical activities took more risk of non-plan cesarean section. Further examined the correlation between individual sleep variables and non-plan cesarean section, it showed that women who suffered from non-plan cesarean section have had fewer sleep hours, more sleep disturbance, and fewer moderate-to-vigorous physical activities. (7)Sleep quality (PSQI) and physical activities are important predictive factors of non-plan cesarean section. It indicated that pregnant women who had poor sleep quality and low physical activities had higher risk of non-plan cesarean section. (8)Depressive symptoms was a related factor of vacuum vaginal delivery. 58.8% of pregnant women who suffered from vacuum vaginal delivery have severe depressive symptoms. From this research it was found that a higher risk of non-plan cesarean section was found in pregnant women who experienced poorer sleep quality and less amount of physical activities. 60% of pregnant women who adopted for vacuum vaginal delivery suffered from serious depressive symptoms. Only moderate-to-vigorous physical activities could improve sleep quality and depressive symptoms. Thus, it is recommended that health practitioners should encourage pregnant women to do some moderate-to-vigorous activities, such as stroll, and antepartum exercise. Pregnant women should avoid static activities to improve sleep quality, decrease depressive symptoms, and decrease negative pregnancy outcomes.
Xin-MinLiao and 廖信閔. "Patients With Asthma COPD Overlap Syndrome (ACOS) Have Higher Risk of Obstructive Sleep Apnea (OSA) And The Severity of OSA May Affect Outcomes of ACOS Patients." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/2shvbq.
Повний текст джерелаZielke, Desiree Joy. "Ecological momentary assessment versus traditional retrospective self-reports as predictors of health-relevant outcomes." Thesis, 2013. http://hdl.handle.net/1805/3523.
Повний текст джерелаEcological momentary assessment (EMA) has been asserted by proponents of the technique as being superior to standard paper-and-pencil measurements in terms of the reliability and validity of the information obtained; however, this claim has not yet been fully evaluated in the literature. Accordingly, the purpose of this study was to evaluate one aspect of this assertion by comparing the utility of EMA and retrospective measures of depressive symptoms in predicting health-relevant biological and behavioral outcomes. It was hypothesized that (1) the EMA measure will have better predictive utility when examining objective sleep quality (a biological outcome), and that (2) the retrospective measure will have better predictive utility when examining blood donation intention (a behavioral outcome). Ninety-six undergraduate females participated in this 2-week study. Depressive symptoms were measured momentarily and retrospectively using the Center for Epidemiological Studies-Depression Scale (CES-D). The biological outcome was assessed by actigraphy, whereas the behavioral outcome was measured via a self-report questionnaire. Unfortunately, it was not possible to fully test these hypotheses due to the failure to observe relationships between the predictor variables and the outcomes. The reported results, although limited, did not provide support for the hypotheses. Supplemental analyses revealed a moderate to high amount of shared variance between the EMA and retrospective measures, a similar extent of random error in both measures, and potentially a greater degree of systematic error in the retrospective measure. Due to the paucity of literature examining the claim of superior reliability and validity of EMA versus retrospective measures, as well as the failure of the current study to evaluate this assertion sufficiently, it appears that this claim remains unfounded. Therefore, suggestions for future research are provided.
Sheehan, Jennifer M. "Maternal factors affecting reported infant sleep outcome." Thesis, 2012. https://vuir.vu.edu.au/21332/.
Повний текст джерела鈴木, 啓介, and Keisuke Suzuki. "Prediction of oral appliance treatment outcome in obstructive sleep apnoea syndrome: a preliminary study." Thesis, 2014. http://hdl.handle.net/2237/20416.
Повний текст джерела"A study of the mediating effects of sleep on stress, health outcome and exam performance." NOVA SOUTHEASTERN UNIVERSITY, 2009. http://pqdtopen.proquest.com/#viewpdf?dispub=3331344.
Повний текст джерелаLEE, MING-CHUNG, and 李明聰. "The Effects Of treating Obstructive Sleep Apnea With Continuous Positive Airway Pressure On Illness Outcome、Anxiety And Depressive Symptoms、And Quality Of Life In Patients Comorbid Obstructive Sleep Apnea With Coronary Artery Disease." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/esdz2n.
Повний текст джерела慈濟大學
人類發展學系碩士班
104
The obstructive sleep apnea (OSA) has been verified to be an important risk factor for causing the cardiovascular diseases. For patients that have suffered from the cardiovascular disease, OSA might increase complications of the cardiovascular disease and lead to bad prognosis. Besides, patients who suffer from OSA generally have high degrees of depression and anxiety. Furthermore, depression and anxiety are also risk factors of prognosis for the coronary artery disease (CAD). The primary therapy method for OSA patients is continuous positive airway pressure (CPAP). This study mainly discusses patients who suffer from both CAD and OSA, and probes into influences exerted on the prognosis of CAD, degrees of depression and anxiety and the quality of life when treating OSA by CPAP. In the recruited hospital of the study, patients who present a stable status and leave hospital after doing a cardiac catheterization procedure for the CAD and simultaneously merge the OSA with the diagnosis of doctors were divided into two groups according to the fact that whether they have accepted CPAP treatment. Within 1 month and after 6 months after taking the treatment of cardiac catheter, six types of questionnaires were tested in two tests, including the Beck Depression Inventory (BDI), the Beck Anxiety Inventory (BAI), the Epworth Sleepiness Scale (ESS), the Berlin Questionnaire-for sleep apnea (BQ), the WHO Quality of Life-BREF (WHOQOL-BREF) and Short - Form 36 (SF-36). In this way, the study compared changes and differences between degrees of depression and anxiety and quality of life of patients who have accepted the CPAP treatment and those who haven’t. In addition, the study also recorded Major Adverse Cardiac and Cerebrovascular Events (MACCEs) of patients in the past six months and one year to compare the correlation between the fact that whether have accepted the CPAP treatment and the prognosis of CAD or different degrees of depression and anxiety and the prognosis of CAD. Patients suffered from both OSA and CAD were divided into two groups according to the fact that whether they have accepted the CPAP treatment. By comparison, basic data, the severity of CAD and the severity of OSA were undifferentiated between two groups, which means that they have the common starting point. MACCEs within 6 months for two groups did not express significant differences while the occurrence of MACCEs of the untreated group after 1 year significantly increased. As to the untreated group, different degrees of depression and anxiety were not significantly associated with MACCEs within 6 months and 1 year. As to conditions of depression and anxiety, changes of BAI and BDI within six months for two groups did not achieve significant difference. Regarding the sleepiness case, ESS within 6 months of two groups also did not present significant differences. With respect to the quality of sleep, BQ fatigue sense for the group with CPAP treatment within 6 months were improved while various classes of BO of the untreated group within 6 months did not show significant variation. As to the quality of life, satisfaction degrees concerning the quality of life shown on the self-assessment in the WHOQOL-BREF by the group of CPAP treatment within 6 months obviously improved. Nevertheless, pains of bodies, according to the SF-36, were remarkably regressed due to the limitation on emotional factors. For the untreated group, the social relationship and self-assessment for satisfaction degrees concerning the quality of life in the WHOQOL-BREF within 6 months, and body functions in SF-36 showed a substantially setback out of the limitation of emotional factors. Moreover, when dividing patients into four groups on the basis of the fact that whether they have taken the CAD/CPAP treatment: (A) a group that takes the CPAP treatment with OSA combines with CAD, (B) an untreated group with OSA combines with CAD, (C) a group that takes the CPAP treatment without OSA combing with CAD, and (D) an untreated group without OSA combining with CAD. From the perspective of anxiety, it could be found that the anxiety of (A) group, (C) group and (D) group presented a more significant improvement than that of (B) group. With same groups as mentioned above, regarding the aspect of depression, (A) group and (C) group presented a more substantial improvement to that of (B) group, while (C) group presented a more significant improvement than that of (D) group in BDI. In recent years, the correlation between OSA and CAD has been repeatedly mentioned. The study reveals that the occurrence of MACCEs would increase if not treating OSA appropriately. It is suggested that CAD patients shall positively screen and take the treatment for dealing with OSA. In the study, depression and anxiety are not main risk factors of the prognosis of CAD. The possible reason for the case is that influences of comorbidities have outdistanced influences of depression and anxiety when OSA merging with CAD. That is, influences of depression and anxiety on the prognosis will be less important when diseases are becoming complex. The sleepiness and quality of sleep in the study did not show great differences throughout the course, whether the patient was or wasn’t treated. It might be caused for the fact that most of subjects of the study are severe OSA patients. Therefore, unlike the treatment for mild illnesses, no significant improvement could be found here in spite of the CPAP treatment of six months. As to differences of the quality of life in the study, the self-assessment of the treated group showed that they feel the improvement of the quality of life, patients, however, have to wear CPAP when sleeping which might make them feel inconvenient, give rise to mental disorders or complications of CPAP and then further lead to bad evaluation concerning some items of the quality of life. In the end, if make comparisons about improvements of depression and anxiety by classifying patients according to facts that whether they suffer from comorbidities of CAD or whether they accept the CPAP treatment, it could be shown that: degrees of comorbidities and whether accept the CPAP treatment could decide differences of improvements of anxiety and depression. In conclusion, this study discovers that the treatment of CPAP positively assists in the prognosis of CAD. Actively screening and treating OSA within CAD patients can reduce the deterioration or relapse of CAD so as to prolong patients’ life-span.