Дисертації з теми "Single spike"
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Miller, Christopher L. "Variation in single kernel hardness within the wheat spike." Thesis, Manhattan, Kan. : Kansas State University, 2008. http://hdl.handle.net/2097/925.
Повний текст джерелаBenda, Jan. "Single neuron dynamics." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2002. http://dx.doi.org/10.18452/14684.
Повний текст джерелаThe single neuron is the basic element of information processing in nervous systems. In this thesis several properties of the dynamics of the generation of spikes are investigated theoretically as well as experimentally. Phase oscillators of different complexity are introduced as models to predict the timing of spikes. The neuron's intensity-response curve is used as a basic parameter in these models to make them easily applicable to real neurons. As a second important aspect of the spiking dynamics, the neuron's phase-resetting curve is used to extend the models. The phase oscillators turn out to be a good approximation of the spiking behavior of a neuron as long as it is stimulated in its super-threshold regime. However, it is shown by comparison with conductance-based models that these models, as well as all other one-dimensional models including the common integrate-and-fire model, fail, if the neuron is stimulated with currents fluctuating around its threshold. Spike-frequency adaptation is a common feature of many neurons. For various ionic currents, as a possible reason for adaptation, a general phenomenological model for the firing rate of adapting neurons is derived from their biophysical properties. This model is defined by the neuron's intensity-response curves and an adaptation time-constant. By means of this model the high-pass properties of spike-frequency adaptation can be quantified. Also the role of adaptation in supression of background noise is discussed. Both the phase oscillators and the adaptation-model are tested on auditory receptor neurons of locusts and the AN1, a primary auditory interneuron of the cricket {Teleogryllus oceanicus}. In both cases the models are in good agreement with the experimental data. By means of the models it is shown that adaptation in the receptor neurons is caused by ionic currents of the spike generator while in the interneuron it is the input which is already adapting. In addition, the influence of spike-frequency adaptation on the recognition of courtship songs is analysed.
Du, Nan, Mahdi Kiani, Christian G. Mayr, Tiangui You, Danilo Bürger, Ilona Skorupa, Oliver G. Schmidt, and Heidemarie Schmidt. "Single pairing spike-timing dependent plasticity in BiFeO3 memristors with a time window of 25ms to 125µs." Universitätsbibliothek Chemnitz, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-171458.
Повний текст джерелаMalvestio, Irene. "Detection of directional interactions between neurons from spike trains." Doctoral thesis, Universitat Pompeu Fabra, 2019. http://hdl.handle.net/10803/666226.
Повний текст джерелаUn problema important en la neurociència és determinar la connexió entre neurones utilitzant dades dels seus trens d’impulsos. Un mètode recent que afronta la detecció de connexions direccionals entre dinàmiques utilitzant processos puntuals és la mesura d’interdependència no lineal L. En aquesta tesi, utilitzem el model de Hindmarsh-Rose per testejar L en presència de soroll i per diferents règims dinàmics. Després comparem el desempenyorament de L en comparació al correlograma lineal i a dues mesures de trens d’impulsos. Finalment, apliquem totes aquestes mesures a dades d’impulsos de neurones obtingudes de senyals intracranials electroencefalogràfiques gravades durant una nit a un pacient amb epilèpsia. Quan utilitzem dades simulades, L demostra que és versàtil, robusta i més sensible que les mesures lineals. En canvi, utilitzant dades reals, les mesures lineals troben més connexions que L, especialment entre neurones en la mateixa àrea del cervell i durant la fase de son d’ones lentes.
Landry, Richard Spencer Jr. "Simulating the Affects of Glutamatergic Afferents on the Firing Pattern of Midbrain Dopamine Neurons." ScholarWorks@UNO, 2006. http://scholarworks.uno.edu/td/299.
Повний текст джерелаHerrera-Valdez, Marco Arieli. "Relationship Between Nearly-Coincident Spiking and Common Excitatory Synaptic Input in Motor Neurons." Diss., The University of Arizona, 2008. http://hdl.handle.net/10150/196051.
Повний текст джерелаTelenczuk, Bartosz. "Crossing the scales." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2011. http://dx.doi.org/10.18452/16404.
Повний текст джерелаDuring its normal function the brain generates strong and measurable electric signals. This phenomenon, which has been known for more than a century, makes it possible to investigate the signal processing in the brain. Nowadays the cellular processes taking part in the generation of the electric signals are well understood. However, most of the neuronal events recruit large populations of cells, whose activities are coordinated spatially and temporally. This coordination allows for summation of activities generated by many neurons leading to extracellular electric signals that can be recorded non-invasively from the scalp by means of electroencephalography (EEG). The temporal structure of the EEG signal does not depend only on the properties of single neurons, but also on their interactions that may be very complex. The complexity hinders the evaluation of the recoded signal with respect to the number of active neurons, the type of response, the degree of synchronisation and the contribution of other processes (such as, learning and attention). In the thesis, the relations between the microscopic (single-neuron) and their macroscopic (EEG) properties will be investigated by means of experimental, data-analytic and theoretical approaches.
Blankenburg, Sven. "Theoretical mechanisms of information filtering in stochastic single neuron models." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät, 2016. http://dx.doi.org/10.18452/17577.
Повний текст джерелаNeurons transmit information about time-dependent input signals via highly non-linear responses, so-called action potentials or spikes. This type of information transmission can be frequency-dependent and allows for preferences for certain stimulus components. A single neuron can transmit either slow components (low pass filter), fast components (high pass filter), or intermediate components (band pass filter) of a time-dependent input signal. Using methods developed in theoretical physics (statistical physics) within the framework of information theory, in this thesis, cell-intrinsic mechanisms are being investigated that can lead to frequency selectivity on the level of information transmission. Various stochastic single neuron models are examined numerically and, if tractable analytically. Ranging from simple spiking models to complex conductance-based models with and without nonlinearities, these models include integrator as well as resonator dynamics. First, spectral information filtering characteristics of different types of stochastic current-based integrator neuron models are being studied. Subsequently, the simple deterministic PIF model is being extended with a stochastic spiking rule, leading to positive correlations between successive interspike intervals (ISIs). Thereafter, models are being examined which show subthreshold resonances (so-called resonator models) and their effects on the spectral information filtering characteristics are being investigated. Finally, the spectral information filtering properties of stochastic linearnonlinear cascade neuron models are being researched by employing different static nonlinearities (SNLs). The trade-off between frequency-dependent signal transmission and the total amount of transmitted information will be demonstrated in all models and constitutes a direct consequence of the nonlinear formulation of the models.
Darling, Ryan Daniel. "Single Cell Analysis of Hippocampal Neural Ensembles during Theta-Triggered Eyeblink Classical Conditioning in the Rabbit." Miami University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=miami1225460517.
Повний текст джерелаNguyen, Van Dong. "Speciation analysis of butyl- and phenyltin compounds in environmental samples by GC separation and atomic spectrometric detection." Doctoral thesis, Umeå : Department of Chemistry, Umeå University, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-892.
Повний текст джерелаErrico, Carmine. "Determination of the influence of SRG anchors on the bond behavior of SRG/FRCM strips bonded to a quasi-brittle substrate." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019.
Знайти повний текст джерелаKurz, Thorben Andreas. "Development of techniques for single dendritic spine analysis." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-148813.
Повний текст джерелаKurz, Thorben Andreas [Verfasser], and Alexander [Akademischer Betreuer] Borst. "Development of techniques for single dendritic spine analysis : spinomics / Thorben Andreas Kurz. Betreuer: Alexander Borst." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2012. http://d-nb.info/102706616X/34.
Повний текст джерелаAmbati, Divya V. "Effect of Design Variables on Biomechanics of Lumbar Spine Implanted with Single, Multilevel and Hybrid Posterior Dynamic Stabilization Systems." University of Toledo / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1290226430.
Повний текст джерелаMorris, Tracy Louise. "Investigation of thoracic spine kinematics in adult sports participants with chronic groin pain during a single leg drop landing task." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86314.
Повний текст джерелаENGLISH ABSTRACT: Chronic groin pain is widespread across many sporting disciplines. The aim of our research was to determine if there are kinematic differences of the thoracic spine in active sports people with chronic groin pain, compared with healthy controls. A cross-sectional descriptive design was followed. Participants were required to complete six single leg drop landings with each leg from a 20cm height. The study was done in the 3D Movement Analysis Laboratory at the University of Stellenbosch. Ten male participants with unilateral or bilateral chronic groin pain of more than 3 months duration and 10 asymptomatic males, matched for age and sports participation, were recruited. The main outcome measures were: thoracic spine angle at initial foot contact, maximum thoracic spine angle, range of movement (ROM) (difference between the minimum and maximum values) and thoracic spine angle at lowest vertical point of the pelvis. This was assessed in all 3 movement planes: the sagittal plane (X plane), the coronal plane (Y plane) and the transverse plane (Z plane). The results of our study showed that for the unilaterally affected groin pain group, the cases landed in significantly more thoracic flexion (P<0.001 with large effect size) and were in significantly more thoracic flexion still at the lowest point. Peak thoracic flexion was significantly more in the cases than the controls. (P<0.001 with medium effect size) The same was true for the bilaterally affected group when landing on the most painful side, although this was not statistically significant. There were no significant differences in the frontal or transverse planes. In the bilaterally painful group, axial rotation ROM was significantly reduced when landing on either leg (worst affected side: P=0.040 with medium effect size and least affected side: p=0.006 with large effect size). The same occurred in the unilaterally affected group, although this was not statistically significant. Our study suggests that, in participants with chronic groin pain, there is greater thoracic forward flexion away from neutral during landing and that total axial rotation ROM during landing is diminished.
AFRIKAANSE OPSOMMING: Kroniese liespyn kom dikwels en in verskeie sportsoorte voor. Die doel van ons studie was om te bepaal of daar kinematiese verskille van die torakale werwelkolom is in aktiewe sportmense met chroniese liespyn, in vergelyking met gesonde kontroles. ‘n Dwars-deursnit beskrywende studiemetode is gevolg, en uitgevoer in die 3D Beweging Analise Laboratorium, Universiteit van Stellenbosch. Deelnemers moes ses landings op een been doen, met elke been, vanaf 'n 20cm hoogte. Tien mans met eensydige of bilaterale chroniese liespyn vir langer as 3 maande, en 10 asimptomatiese mans (ooreenstemmende ouderdom en sport deelname) het deelgeneem. Die hoof uitkomste wat gemeet is, was torakale werwelkolom krommingshoek by aanvanklike voet-kontak, maksimum torakale werwelkolom krommingshoek, omvang van beweging (OVB) (verskil tussen die minimum en maksimum waardes) en torakale werwelkolom krommingshoek by die laagste punt van die bekken. Dit is beoordeel in al 3 beweging vlakke: die sagittale (X) vlak, die koronale/frontale (Y) vlak en die transversale (Z) vlak. Die resultate van die studie het getoon dat, in die eensydig-geaffekteerde liespyn groep, die deelnemers in beduidend meer torakale fleksie geland het(P < 0.001, met 'n groot effekgrootte), asook met aansienlik meer torakale fleksie by die laagste punt na landing. Piek torakale fleksie was aansienlik meer in die liespyn-gevalle as in die kontroles. (P < 0.001, met middelmatige effekgrootte ) Dieselfde het vir die bilateraalgeaffekteerde groep gegeld wanneer hulle op hul mees pynlike kant geland het, hoewel dit nie statisties beduidend was nie. Daar was geen betekenisvolle verskille in die frontale of transversale vlakke van beweging nie. In die bilateraal pynlike groep, was aksiale rotasie OVB aansienlik verminder wanneer die gevalle op hul pynlikste been óf op hul minder pynlike been geland het ( mees pynlike been : P = 0,040, met 'n middelmatige effekgrootte en minder pynlike been : p = 0,006, met 'n groot effekgrootte ). Dieselfde het in die eensydig-geaffekteerde groep gebeur, hoewel dit nie statisties beduidend was nie. Ons studie dui daarop dat, in deelnemers met chroniese liespyn, daar meer torokale fleksie weg van neutraal tydens landing is en dat die totale aksiale rotasie OVB tydens die landing verminder is, in vergelyking met die kontrolegroep.
Küffner, Mercedes [Verfasser], and Michael [Akademischer Betreuer] Frotscher. "Ultrastructural analysis of spine apparatus in CA3 pyramidal neurons following single cell electroporation in Synaptopodin Knockout - mice = Elektronenmikroskopische Untersuchung des Spine-Apparats in CA3 Pyramidenzellen mittels Einzelzell-Elektroporation in Synaptopodin-defizienten Mäusen." Freiburg : Universität, 2013. http://d-nb.info/1115495283/34.
Повний текст джерелаDare, Michael Robert. "Investigation of hip kinematics in adult sports participants during single leg drop landing with chronic groin pain." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86334.
Повний текст джерелаENGLISH ABSTRACT: Introduction-Groin injuries are among the top six most cited injuries in soccer and account for 10-18 per cent of all injuries reported in contact sport. Groin pain can result from a variety of pathologies, but according to literature, 63 per cent of groin pain is due to adductor pathology. Objective-The objective of this study was to explore if there are kinematic differences in the hip joint in sports participants with groin pain compared to matched healthy controls. Study design A cross sectional, descriptive study was conducted. Study setting-The study was conducted at the FNB -3D motion analysis laboratory at the University of Stellenbosch, South Africa. Outcome variables-The dependent variables included hip kinematics in the sagittal, frontal and transverse planes at foot strike, lowest vertical point of the pelvis and total range of hip motion during a single leg drop landing. Methodology-The study sample comprised 20 male club level soccer-and, rugby players, running and cycling participants between the ages of 18-55 years of age. Ten of the subjects had chronic groin pain and the other ten were healthy matched controls. An eight-camera Vicon system was used to analyse the kinematics of the hip joint during single leg drop landing. For the purpose of comparison, the data was analysed for participants with unilateral groin pain and matched controls (n=14) and participants with bilateral groin pain and controls (n=6). The full set of data was subdivided for analysis into three distinct sub-groups. Unilaterally injured groin cases (n=7) were matched with seven healthy controls for analysis. Bilaterally injured groin cases (n=3) were matched with three healthy controls. Results-Cases with unilateral groin pain at initial contact had significantly more abduction of the hip joint when compared to controls (p<0.05). The effect size of this difference was large (0.94). Cases with unilateral groin pain also demonstrated greater hip internal rotation while the controls had external rotation (p<0.05) during a drop landing activity. Bilaterally injured groin cases landed with significantly (p=?) greater ranges of hip flexion as well as in significantly (p=?) more hip abduction during a drop landing activity. They also demonstrated greater total range of motion in the frontal plan when compared to controls. Groin pain cases overall demonstrated greater ranges of motion and tended to land in more abduction compared to controls. Conclusion-This study found that during a single leg drop landing, sports participants with unilateral chronic groin pain landed with significantly greater hip abduction and exhibited larger total range of motion in the transverse plane, which may indicate impaired stability of the hip complex when compared to controls.
AFRIKAANSE OPSOMMING: Inleiding-Liesbeserings is een van die top ses mees prominente sokker beserings. Dit beloop 10-18 persent van alle beserings wat in kontaksport aangemeld word. Liespyn kan die gevolg wees van ‘n verskeidenheid patologië, maar volgens die literatuur is 63 persent van liespyn as gevolg adduktor patologie. Doelwitte-Die doelwit van hierdie studie was om ondersoek in te stel of daar enige kinematiese veranderinge in die heupgewrig is in spelers met liespyn in vergelyking met dieselfde vergelykbare spelers sonder liespyn. Studie Ontwerp-‘n Deursnit, beskrywende studie was onderneem. Studie Omgewing-Die studie was uitgevoer by die FNB-3D bewegingsanalise laboratorium van die Stellenbosch Universiteit, Suid-Afrika. Uitkomsveranderlikes-Die afhanklike veranderlikes het in gesluit die heup kinematika in die sagitale, frontale en transvers vlakke met voet kontak endie laagste vertikale punt van die pelvis sowel as die totale heup omvang van beweging gedurende een been landing. Metodologie-Die studie populasie het bestaan uit 20 manlike sokker- en, rugbyspelers, hardlopers en fietsryers tussen die ouderdomme van 18 en 55 jaar. Tien van die deelnemers het kroniese liespyn gehad en die ander tien in die gelyke gesonde groep was sonder liespyn. Die agt kamera Vicon sisteem was gebruik om die kinematika van die heupgewrig te analseer tydens een been landing. Vir die doel om ‘n vergelyking te kan maak, was die data geanaliseer van deelnemers met unilaterale liespyn en die vergelykende groep sonder liespyn (n=14) en deelnemers met bilaterale liespyn en hulle vergelykende groep sonder liespyn (n=6).. Die volledige stel data was onderverdeel in drie afsonderlike sub groepe. Vir die analiese was unilaterale liesbeserings (n=7) vergelyk met sewe deelnemers sonder liespyn in die kontrolegroep. Deelnemers met bilaterale liesbeserings (n=3) was vergelyk met drie in die kontrolegroep. Resultate-Die deelnemers met unilaterale liespyn het met eerste kontak beduidend meer abduksie van die heupgewrig gehad in vergelyking met die kontrolegroep (p<0.05). Die effek van hierdie verskil was groot (0.94). Die deelnemers met unilaterale liespyn het ook ‘n grooter interne rotasie getoon, terwyl die kontrole groep meer eksterne rotasie gedemonstreer het (p<0.05) met landing. Deelnemers met bilaterale liespyn het beduidend (p=?) meer heup fleksie en abduksie omvang van beweging tydens landing. Hulle het ook ‘n groter totale heup omvang van beweging in die frontale vlak gehad in vergelyking met die kontrolegroep. Deelnemers met liespyn het oor die algemeen ‘n grooter omvang van beweging getoon, en was geneig om met meer abduksie van die heup te land as die kontrolegroep. Gevolgtrekking-Die studie toon dat deelnemers met kroniese unilaterale liespyn, tydens een been landing, beduidende meerheup abduksie toon en dat die heup in die transverse vlak meer totale omvang van beweging gebruik wat kan dui op onstabiliteit in die heupkompleks in vergelyking met die kontrolegroep.
Chen, Jian Hua [Verfasser], Peter Jomo [Akademischer Betreuer] Walla, Reinhard [Akademischer Betreuer] Jahn, and Andreas [Akademischer Betreuer] Janshoff. "Spatial-temporal actin dynamics during synaptic plasticity of single dendritic spine investigated by two-photon fluorescence correlation spectroscopy / Jian Hua Chen. Gutachter: Reinhard Jahn ; Andreas Janshoff. Betreuer: Peter Jomo Walla." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://d-nb.info/1045776246/34.
Повний текст джерелаChen, Jian Hua Verfasser], Peter Jomo [Akademischer Betreuer] [Walla, Reinhard [Akademischer Betreuer] Jahn, and Andreas [Akademischer Betreuer] Janshoff. "Spatial-temporal actin dynamics during synaptic plasticity of single dendritic spine investigated by two-photon fluorescence correlation spectroscopy / Jian Hua Chen. Gutachter: Reinhard Jahn ; Andreas Janshoff. Betreuer: Peter Jomo Walla." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://nbn-resolving.de/urn:nbn:de:gbv:7-11858/00-1735-0000-0022-609F-1-7.
Повний текст джерелаMayo, Andrew. "A biomechanical study of top screw pullout in anterior scoliosis correction constructs." Thesis, Queensland University of Technology, 2007. https://eprints.qut.edu.au/17152/1/Andrew_Elton_Mayo_Thesis.pdf.
Повний текст джерелаMayo, Andrew. "A biomechanical study of top screw pullout in anterior scoliosis correction constructs." Queensland University of Technology, 2007. http://eprints.qut.edu.au/17152/.
Повний текст джерелаChazeau, Anael. "Rôle de l’organisation du cytosquelette d’actine branché et des adhésions N-cadhérine dans la dynamique des épines dendritiques." Thesis, Bordeaux 2, 2012. http://www.theses.fr/2012BOR21967/document.
Повний текст джерелаDendritic spines are tiny post-synaptic protrusions exhibiting changes in morphology correlated with synaptic plasticity. They originate from motile dendritic filopodia, which enlarge after contacting axons. These morphological changes involve a wide number of molecular actors, including actin-binding proteins, and adhesion molecules. However, how these various molecular components are coordinated temporally and spatially to tune changes in spine shape remains unclear. Furthermore, conventional photonic microscopy techniques could not achieved the spatial resolution required to study the dynamic nanoscale organization of these proteins within the micron size dendritic spines. The objective of my Ph.D. was to unravel how actin-binding proteins and N-cadherin adhesion regulate the organization and dynamics of F-actin network in dendritic spines. In a first study, we measured the motility of dendritic filopodia and spines by time lapse imaging of actin-GFP in primary hippocampal neurons. We combined those measurements with: 1) manipulation of N-cadherin coated beads with optical tweezers, or micropatterns to control the timing and location of nascent N-cadherin adhesions, 2) pharmacological stimulation of myosin II to trigger contraction of the F-actin/myosin network and 3) expression of non-adhesive N-cadherin mutants to compete for the interaction between N-cadherin adhesion and F-actin. Using these different approaches we demonstrated that the stabilization of dendritic filopodia into mature spines was dependent on the engagement of a molecular clutch between trans-synaptic N-cadherin adhesions and the myosin driven F-actin flow. In a second study, we used super resolution microscopy (PALM and dSTORM) and single protein tracking (sptPALM) to study the dynamic nanoscale organizations of branched actin networks within dendritic spines. Using these technics, we characterized within dendritic spines, the localization and dynamics of actin, Arp2/3 complex, WAVE complex, IRSp53, VASP and Rac-1. We established that, opposite to classical motile structures such as the lamellipodium, branched F-actin networks in dendritic spines are not formed at the tip of membrane protrusions and incorporated in a retrograde flow. On the contrary, they are growing outwards from the PSD generating membrane protrusions responsible for spine motility. We also show that a thigh control of Rac1 activity is required to maintain dendritic spine morphology and branched actin network organization. Altogether, these studies point out the role of the nanoscale functional organization of F-actin networks and its linkage to adhesion proteins in the regulation of dendritic spine formation and dynamics. These findings may have important implications in the understanding of spine morphology changes driven by synaptic activity
Yang, Fuchan, and 楊富全. "Unsupervised Spike Sorting with Improved Single-Linkage Method." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/76462628804011661813.
Повний текст джерела國立交通大學
電機與控制工程系所
95
Spike sorting is the one of the based in many neuroscience researches. The targets of spike sorting are to research the action potential of neuron and to classify the difference spikes produced by difference neurons. The recorded neuron signals is often diffusion and astronomical. It may also record the signals produced by two or more neurons. A lot of neuron signals make the procedure of spike sorting slow and weighty. Hence the spike sorting needs much artificial operations to complete. Many researches attach importance to the accuracy of classification and the performance under the simulate situation. The first lead to the lack of convenience, and the later lacks the test of real applications to support. Hence the spike sorting can’t conveniently be used for signal analysis. The thesis uses a new spike sorting method for multiunit neuron signals. The method respectively use wavelet transform and principal components analysis to extract the spike waveform features. Then the spike classification method is based on improved signal linkage method and grey theory to arrive automatically procedure. The procedure is unsupervised and reasonable and hence it can make a fast, effective and convenient spike sorting method. The method is tested by strict simulation spikes and compared with some other classification methods. Subsequently the method analyzes the neuron signals recorded from human. The results also show that the method of the thesis has an unsupervised spike sorting procedure.
Chuang, Chung-Ting, and 莊仲庭. "Biomechanical analysis of take-off spike movement by single-foot." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/98482240037652424042.
Повний текст джерела國立臺北教育大學
體育學系碩士班
95
The purpose of this study was to investigate the kinematics and kinetics parameters change of human body take-off spike movement by single-foot in women’s volleyball players. Five female volleyball players (ages:21.4±3.05yrs , weight:66.2±4.66kg , height:172±4.64cm,practice experience: 11.4±1.95 yrs ; mean±SD) were served as subject for the study. Two CPL MS25K high speed cameras(100Hz)was synchronized with an AMTI force platform(1000Hz) to collect the biomechanical parameters of taking-off spike movement by single-foot . The images were processed with Kwon motion analysis system to obtain kinematics parameters of run-up period, take-off period, and air-motion period, and the values were analyzed with Dasy Lab 6.0 software to obtain kinetics parameters changes of take-off period. After comparing with previously report, conclusion was as follow: when players use take-off spike movement by single-foot, the strides should increase progressively after observing the ball’s direction, and raise the height of jump by getting faster horizontal and vertical velocity of body gravity. In order to avoid increasing the time of take-off, the body gravity is inadvisable to drop so much. In air motion period, player’s movement of arm swing will influences the time of spike, if we emphasize the quick offensive, it should reduce the movement of arm swing to decrease the time of spike. When spiking, the joint of elbow should flex by a little range to make forearm powerful.
Quang, Trong-Nha, and 廣眾雅. "Single-Stage Current-Fed Power Factor Correction Converters with Low Voltage Spike." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/26277710377739885342.
Повний текст джерела國立臺灣科技大學
電子工程系
102
Previous studies on the single-stage power factor correction (PFC) converters expose some shortcomings such as high voltage spike on power devices, discontinuous conduction mode (DCM) input current and switching frequency variation. These undesired factors cause efficiency limitation, high electromagnetic interference (EMI) intensity and high-voltage high-cost power device use. In this dissertation, three topologies are proposed for PFC applications. For low power applications, two topologies named current-fed flyback and zero-voltage-switching (ZVS) current-fed flyback PFC converters featuring voltage-spike-free on MOSFET, high power quality and ZVS achievement are proposed. For high power applications, a novel current-fed full-bridge (CFFB) PFC converter is proposed to improve efficiency, input current quality and reduce common mode (CM) noise. Utilizing quasi z-source configuration, the voltage spike on the MOSFETs is effectively eliminated by capacitive clamping circuit without power loss consumption. Low voltage MOSFETs with low on-resistance Rds(on) are used to improve efficiency. The input current is continuous conduction mode (CCM) operation. Additionally, to evaluate the conducted EMI behavior, the differential mode (DM) loop and CM loop models are also thoroughly analyzed and presented in this study. Several laboratory prototypes of the conventional PFC converters and proposed PFC converters were built to compare their performances and demonstrate the circuit feasibility. The experimental results showed that the proposed topologies completely eliminated the voltage spikes on the MOSFETs. The efficiency improved by using low Rds(on) MOSFETs. The input current was CCM operation.
Narayana, Gopalakrishna. "Investigation of an Axisymmetric Spiked Body in a Hypersonic Shock Tunnel." Thesis, 2019. https://etd.iisc.ac.in/handle/2005/4401.
Повний текст джерелаISRO
Harward, Stephen Cannada. "BDNF-TrkB Signaling in Single-Spine Structural Plasticity." Diss., 2016. http://hdl.handle.net/10161/12096.
Повний текст джерелаMultiple lines of evidence reveal that activation of the tropomyosin related kinase B (TrkB) receptor is a critical molecular mechanism underlying status epilepticus (SE) induced epilepsy development. However, the cellular consequences of such signaling remain unknown. To this point, localization of SE-induced TrkB activation to CA1 apical dendritic spines provides an anatomic clue pointing to Schaffer collateral-CA1 synaptic plasticity as one potential cellular consequence of TrkB activation. Here, we combine two-photon glutamate uncaging with two photon fluorescence lifetime imaging microscopy (2pFLIM) of fluorescence resonance energy transfer (FRET)-based sensors to specifically investigate the roles of TrkB and its canonical ligand brain derived neurotrophic factor (BDNF) in dendritic spine structural plasticity (sLTP) of CA1 pyramidal neurons in cultured hippocampal slices of rodents. To begin, we demonstrate a critical role for post-synaptic TrkB and post-synaptic BDNF in sLTP. Building on these findings, we develop a novel FRET-based sensor for TrkB activation that can report both BDNF and non-BDNF activation in a specific and reversible manner. Using this sensor, we monitor the spatiotemporal dynamics of TrkB activity during single-spine sLTP. In response to glutamate uncaging, we report a rapid (onset less than 1 minute) and sustained (lasting at least 20 minutes) activation of TrkB in the stimulated spine that depends on N-methyl-D-aspartate receptor (NMDAR)-Ca2+/Calmodulin dependent kinase II (CaMKII) signaling as well as post-synaptically synthesized BDNF. Consistent with these findings, we also demonstrate rapid, glutamate uncaging-evoked, time-locked release of BDNF from single dendritic spines using BDNF fused to superecliptic pHluorin (SEP). Finally, to elucidate the molecular mechanisms by which TrkB activation leads to sLTP, we examined the dependence of Rho GTPase activity - known mediators of sLTP - on BDNF-TrkB signaling. Through the use of previously described FRET-based sensors, we find that the activities of ras-related C3 botulinum toxin substrate 1 (Rac1) and cell division control protein 42 (Cdc42) require BDNF-TrkB signaling. Taken together, these findings reveal a spine-autonomous, autocrine signaling mechanism involving NMDAR-CaMKII dependent BDNF release from stimulated dendritic spines leading to TrkB activation and subsequent activation of the downstream molecules Rac1 and Cdc42 in these same spines that proves critical for sLTP. In conclusion, these results highlight structural plasticity as one cellular consequence of CA1 dendritic spine TrkB activation that may potentially contribute to larger, circuit-level changes underlying SE-induced epilepsy.
Dissertation
Shi-Tin, Lin, and 林式庭. "Study of Single-electron Transistor Model for SPICE Analysis." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/59323458785523715586.
Повний текст джерела國立暨南國際大學
電機工程學系
91
Due to the rapid progress in nano-fabrication technologies, various nano devices have been successfully fabricated. Among them, single-electron devices have drawn many researchers’ attention due to their very promising characteristics, such as ultimate low power consumption, down-scalability to nano-scale, high density and high switching speed. Basic logic circuits constructed with single electron devices as the basic building unit have been practically implemented. Therefore, the need for new circuit simulator that can simulate single- electron circuits is urgent. If the simulator can be combined with the existing circuits simulator such as SPICE, one can further simulate those hybrid circuits that include both the single electron devices and the conventional circuit elements. Since single electron simulators based on Monte Carlo method usually involve complicated calculations and take very long computation time, in this thesis we focus on single-electron transistors’ macro model and analytical model suitable for SPICE analysis. Based on the existing macro model and analytical model found in the literature, we developed an improved macro model and an improved analytical model for single electron transistors that can be used in SPICE circuit analysis. When compared with the well-accepted Monte Carlo single electron simulator SIMON 2.0, we found that both of our proposed models can correctly predict the terminal characteristics of single electron transistors with little computation time. We also applied our proposed macro model to single electron inverters and a practical single electron XOR logic gates and obtained the voltage transfer characteristics and output waveforms successfully. In this thesis, we also reported the fabrication of a nanowire transfer resistor by using atomic force microscopy based on scanning probe lithography. From the measured characteristics of the nanowire transfer resistor, we found that they are quite different from those of the single electron transistors. We believed that it is worthy of further study of the nature of the nanowire transfer resistor.
Blakeney, Carmen. "The effect of a single versus multiple cervical spine manipulations on peak torque of the rotator cuff muscles in asymptomatic subjects with cervical spine fixation." Thesis, 2009. http://hdl.handle.net/10321/457.
Повний текст джерелаAim: The aim of the study was to assess the effect of a single versus multiple cervical spine manipulations, over a two week period, on peak torque of the rotator cuff muscles utilizing the Cybex Orthotron II Isokinetic Rehabilitation System. This study was a pre and post experimental investigation. Method: Forty asymptomatic (in terms of neck and shoulder pain) male chiropractic students were stratified into two equal groups of twenty subjects to ensure that each group consisted of an equal number of subjects from each year of study. All subjects underwent a familiarisation session on the Cybex Orthotron II Isokinetic Rehabilitation System. Group One received a single manipulation. Rotator cuff peak torque was measured pre-manipulation, immediately post manipulation and at a two-week follow up. Group Two received four manipulations over a two week period. Rotator cuff peak torque was measured pre and immediately post the first manipulation. A third rotator cuff peak torque measurement was taken two weeks after the first manipulation. Results: There was no statistically significant effect of a single or multiple manipulations on rotator cuff peak torque (abduction, adduction, internal rotation and external rotation). Inter-group analysis revealed a trend of an effect for abduction as the single manipulation increased at the two-week follow up and the multiple manipulation group decreased; however, this was not statistically significant. Conclusion: No statistically significant results were found possibly due to small sample size and the fact that objective measurements were only taken at the beginning and the end of the research processes and not at regular intervals throughout the study.Further studies are needed to determine the effects of multiple manipulations on peripheral muscle activity, including the treatment of symptomatic patients with rotator cuff pathology. It is also recommended that EMG readings be done in conjunction with peak torque measures to determine muscle activity.
Gregory, Diane Elizabeth. "The Influence of the Tensile Material Properties of Single Annulus Fibrosus Lamellae and the Interlamellar Matrix Strength on Disc Herniation and Progression." Thesis, 2009. http://hdl.handle.net/10012/4525.
Повний текст джерелаChen, Jian Hua. "Spatial-temporal actin dynamics during synaptic plasticity of single dendritic spine investigated by two- photon fluorescence correlation spectroscopy." Doctoral thesis, 2013. http://hdl.handle.net/11858/00-1735-0000-0022-609F-1.
Повний текст джерелаRogers, Tamara. "The effect of a single application of muscle energy technique on pressure pain thresholds in the lumbar spine." Thesis, 2005. https://vuir.vu.edu.au/887/.
Повний текст джерелаRogers, Tamara. "The effect of a single application of muscle energy technique on pressure pain thresholds in the lumbar spine." 2005. http://eprints.vu.edu.au/887/1/Rogers_et.al_2005.pdf.
Повний текст джерелаCeong, Hailey Hyekyeong. "The morphosyntax of clause typing: single, double, periphrastic, and multifunctional complementizers in Korean." Thesis, 2019. http://hdl.handle.net/1828/10815.
Повний текст джерелаGraduate
Lee, Seok-Jin. "Spatiotemporal Dynamics of Calcium/calmodulin-dependent Kinase II in Single Dendritic Spines During Synaptic Plasticity." Diss., 2011. http://hdl.handle.net/10161/3818.
Повний текст джерелаSynaptic plasticity is the leading candidate for the cellular/molecular basis of learning and memory. One of the key molecules involved in synaptic plasticity is Calcium/calmodulin-dependent Kinase II (CaMKII). Synaptic plasticity can be expressed at a single dendritic spine independent of its neighboring dendritic spines. Here, we investigated how long the activity of CaMKII lasts during synaptic plasticity of single dendritic spines. We found that CaMKII activity lasted ~2 minutes during synaptic plasticity and was restricted to the dendritic spines undergoing synaptic plasticity while nearby dendritic spines did not show any change in the level of CaMKII activity. Our experimental data argue against the persistent activation of CaMKII in dendritic spines undergoing synaptic plasticity and suggest that the activity of CaMKII is a spine-specific biochemical signal necessary for synapse-specificity of synaptic plasticity. We provide a biophysical explanation of how spine-specific CaMKII activation can be achieved during synaptic plasticity. We also found that CaMKII is activated by highly localized calcium influx in the proximity of Voltage-dependent Calcium Channels (VDCCs) and a different set of VDCCs and their respective Ca2+ nanodomains are responsible for the differential activation of CaMKII between dendritic spines and dendritic shafts.
Dissertation
Rowley, Neil Charles. "The relative effectiveness of a single dry needle insertion compared to multiple fanning dry needle insertions in the treatment of myofasciitis in the cervical and upper thoracic spine." Thesis, 2001. http://hdl.handle.net/10321/1863.
Повний текст джерелаMyofascial Pain Syndrome (MPS) is a clinical syndrome of soft tissue pain arising from skeletal muscle. It is manifested by characteristic trigger points (TrPs) in palpable taut bands of muscle fibres with typical referred pain patterns, restricted range of motion and local twitch responses. Treatment of MPS appears to be aimed at disrupting the reverberating neural circuits responsible for the self-perpetuation of the pain-spasm pain cycle. This occurs through inactivating the active TrP through releasing the taut bands with various techniques including massage, ischaemie compression, spray and stretch, ultrasound, hydrocollator moist heat, trigger point injection, dry needling, and TENS. There are many treatments available yet little research substantiating efficiency of one specific therapy over another, with the result that choice of treatment often becomes based on personal preferences rather than clinical evidence. Among many authors, dry needling has been shown to be an effective form of treatment. The therapeutic effect of dry needling relies on the mechanical disruption or direct stimulation of the TrP and that the strongest analgesic effect is achieved when the most painful spot is precisely reached with a fme needle, normally an acupuncture needle. This immediate analgesia produced by needle puncture of a TrP has been termed the
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