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Статті в журналах з теми "Sequential controlled sensing"
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Deshmukh, Aditya, Venugopal V. Veeravalli, and Srikrishna Bhashyam. "Sequential controlled sensing for composite multihypothesis testing." Sequential Analysis 40, no. 2 (April 3, 2021): 259–89. http://dx.doi.org/10.1080/07474946.2021.1912525.
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Nitinawarat, Sirin, and Venupogal V. Veeravalli. "Controlled Sensing for Sequential Multihypothesis Testing with Controlled Markovian Observations and Non-Uniform Control Cost." Sequential Analysis 34, no. 1 (January 2, 2015): 1–24. http://dx.doi.org/10.1080/07474946.2014.961864.
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Ghosh, Debanjana, Austin Atkinson, Jaclyn Gibson, Harini Subbaiahgari, Weihua Ming, Clifford Padgett, Karelle S. Aiken, and Shainaz M. Landge. "1,2,3-Triazoles: Controlled Switches in Logic Gate Applications." Sensors 23, no. 15 (August 7, 2023): 7000. http://dx.doi.org/10.3390/s23157000.
Повний текст джерелаАнотація:
A 1,2,3-triazole-based chemosensor is used for selective switching in logic gate operations through colorimetric and fluorometric response mechanisms. The molecular probe synthesized via “click chemistry” resulted in a non-fluorescent 1,4-diaryl-1,2,3-triazole with a phenol moiety (PTP). However, upon sensing fluoride, it TURNS ON the molecule’s fluorescence. The TURN-OFF order occurs through fluorescence quenching of the sensor when metal ions, e.g., Cu2+, and Zn2+, are added to the PTP-fluoride ensemble. A detailed characterization using Nuclear Magnetic Resonance (NMR) spectroscopy in a sequential titration study substantiated the photophysical characteristics of PTP through UV-Vis absorption and fluorescence profiles. A combination of fluorescence OFF-ON-OFF sequences provides evidence of 1,2,3-triazoles being controlled switches applicable to multimodal logic operations. The “INH” gate was constructed based on the fluorescence output of PTP when the inputs are F− and Zn2+. The “IMP” and “OR” gates were created on the colorimetric output responses using the probe’s absorption with multiple inputs (F− and Zn2+ or Cu2+). The PTP sensor is the best example of the “Write-Read-Erase-Read” mimic.
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Chang, Hsing Cheng, Ya Hui Chen, Shyan Lung Lin, and San Shan Hung. "An Optical Centrifugal-and-Pneumatic Controlled Microfluidic System for Sensing Real-Time Biochemical Reactions." Applied Mechanics and Materials 397-400 (September 2013): 1733–37. http://dx.doi.org/10.4028/www.scientific.net/amm.397-400.1733.
Повний текст джерелаАнотація:
An optical real-time pneumatic-and-centrifugal controlled microfluidic detection system for dynamic information acquisition is developed based on the quasi-stationary imaging technique. The programmable airflow applied on the centrifugal microstructures for improving efficiency in samples separation. The dynamic characteristic of a loaded disc is stable with vibrating under 0.3 mm at a speed of 1000 rpm by applying 3 bar-induced pneumatic forces on a 12 cm-diameter disc. A conversion model for converting RGB images into CIEL*a*b*color space have been used to enhance the inspection images. A linear relationship between threshold frequency and sample density is 167 rpm/g/cm3. The pressures between 0.1 and 0.5 bars are applied to bias microflow from 15° to 80°. The conduction angles between 30° and 90° have better pneumatic control. The control efficiency observed up to 89% and the largest microflow biased angle reached 80°. The pneumatic force dominates microfluidic behaviors when the force is greater than 10 times the centrifugal force. A sequential of triple-reservoir tests has been verified by analyzing enhanced optical images in separation using arranged acid-base indicators for pH reactions.
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Lupp, Claudia, and Edward G. Ruby. "Vibrio fischeri Uses Two Quorum-Sensing Systems for the Regulation of Early and Late Colonization Factors." Journal of Bacteriology 187, no. 11 (June 1, 2005): 3620–29. http://dx.doi.org/10.1128/jb.187.11.3620-3629.2005.
Повний текст джерелаАнотація:
ABSTRACT Vibrio fischeri possesses two quorum-sensing systems, ain and lux, using acyl homoserine lactones as signaling molecules. We have demonstrated previously that the ain system activates luminescence gene expression at lower cell densities than those required for lux system activation and that both systems are essential for persistent colonization of the squid host, Euprymna scolopes. Here, we asked whether the relative contributions of the two systems are also important at different colonization stages. Inactivation of ain, but not lux, quorum-sensing genes delayed initiation of the symbiotic relationship. In addition, our data suggest that lux quorum sensing is not fully active in the early stages of colonization, implying that this system is not required until later in the symbiosis. The V. fischeri luxI mutant does not express detectable light levels in symbiosis yet initiates colonization as well as the wild type, suggesting that ain quorum sensing regulates colonization factors other than luminescence. We used a recently developed V. fischeri microarray to identify genes that are controlled by ain quorum sensing and could be responsible for the initiation defect. We found 30 differentially regulated genes, including the repression of a number of motility genes. Consistent with these data, ain quorum-sensing mutants displayed an altered motility behavior in vitro. Taken together, these data suggest that the sequential activation of these two quorum-sensing systems with increasing cell density allows the specific regulation of early colonization factors (e.g., motility) by ain quorum sensing, whereas late colonization factors (e.g., luminescence) are preferentially regulated by lux quorum sensing.
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Ni, Songbo, Jessica Leemann, Ivo Buttinoni, Lucio Isa, and Heiko Wolf. "Programmable colloidal molecules from sequential capillarity-assisted particle assembly." Science Advances 2, no. 4 (April 2016): e1501779. http://dx.doi.org/10.1126/sciadv.1501779.
Повний текст джерелаАнотація:
The assembly of artificial nanostructured and microstructured materials which display structures and functionalities that mimic nature’s complexity requires building blocks with specific and directional interactions, analogous to those displayed at the molecular level. Despite remarkable progress in synthesizing “patchy” particles encoding anisotropic interactions, most current methods are restricted to integrating up to two compositional patches on a single “molecule” and to objects with simple shapes. Currently, decoupling functionality and shape to achieve full compositional and geometrical programmability remains an elusive task. We use sequential capillarity-assisted particle assembly which uniquely fulfills the demands described above. This is a new method based on simple, yet essential, adaptations to the well-known capillary assembly of particles over topographical templates. Tuning the depth of the assembly sites (traps) and the surface tension of moving droplets of colloidal suspensions enables controlled stepwise filling of traps to “synthesize” colloidal molecules. After deposition and mechanical linkage, the colloidal molecules can be dispersed in a solvent. The template’s shape solely controls the molecule’s geometry, whereas the filling sequence independently determines its composition. No specific surface chemistry is required, and multifunctional molecules with organic and inorganic moieties can be fabricated. We demonstrate the “synthesis” of a library of structures, ranging from dumbbells and triangles to units resembling bar codes, block copolymers, surfactants, and three-dimensional chiral objects. The full programmability of our approach opens up new directions not only for assembling and studying complex materials with single-particle-level control but also for fabricating new microscale devices for sensing, patterning, and delivery applications.
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Oviedo-Boyso, Javier, Alejandro Bravo-Patiño, and Víctor M. Baizabal-Aguirre. "Collaborative Action of Toll-Like and Nod-Like Receptors as Modulators of the Inflammatory Response to Pathogenic Bacteria." Mediators of Inflammation 2014 (2014): 1–16. http://dx.doi.org/10.1155/2014/432785.
Повний текст джерелаАнотація:
Early sensing of pathogenic bacteria by the host immune system is important to develop effective mechanisms to kill the invader. Microbial recognition, activation of signaling pathways, and effector mechanisms are sequential events that must be highly controlled to successfully eliminate the pathogen. Host recognizes pathogens through pattern-recognition receptors (PRRs) that sense pathogen-associated molecular patterns (PAMPs). Some of these PRRs include Toll-like receptors (TLRs), nucleotide-binding oligomerization domain-like receptors (NLRs), retinoic acid-inducible gene-I- (RIG-I-) like receptors (RLRs), and C-type lectin receptors (CLRs). TLRs and NLRs are PRRs that play a key role in recognition of extracellular and intracellular bacteria and control the inflammatory response. The activation of TLRs and NLRs by their respective ligands activates downstream signaling pathways that converge on activation of transcription factors, such as nuclear factor-kappaB (NF-κB), activator protein-1 (AP-1) or interferon regulatory factors (IRFs), leading to expression of inflammatory cytokines and antimicrobial molecules. The goal of this review is to discuss how the TLRs and NRLs signaling pathways collaborate in a cooperative or synergistic manner to counteract the infectious agents. A deep knowledge of the biochemical events initiated by each of these receptors will undoubtedly have a high impact in the design of more effective strategies to control inflammation.
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Nakane, Daisuke, and Takayuki Nishizaka. "Asymmetric distribution of type IV pili triggered by directional light in unicellular cyanobacteria." Proceedings of the National Academy of Sciences 114, no. 25 (June 5, 2017): 6593–98. http://dx.doi.org/10.1073/pnas.1702395114.
Повний текст джерелаАнотація:
The type IV pili (T4P) system is a supermolecular machine observed in prokaryotes. Cells repeat the cycle of T4P extension, surface attachment, and retraction to drive twitching motility. Although the properties of T4P as a motor have been scrutinized with biophysics techniques, the mechanism of regulation remains unclear. Here we provided the framework of the T4P dynamics at the single-cell level inSynechocystissp. PCC6803, which can recognize light direction. We demonstrated that the dynamics was detected by fluorescent beads under an optical microscope and controlled by blue light that induces negative phototaxis; extension and retraction of T4P was activated at the forward side of lateral illumination to move away from the light source. Additionally, we directly visualized each pilus by fluorescent labeling, allowing us to quantify their asymmetric distribution. Finally, quantitative analyses of cell tracking indicated that T4P was generated uniformly within 0.2 min after blue-light exposure, and within the next 1 min the activation became asymmetric along the light axis to achieve directional cell motility; this process was mediated by the photo-sensing protein, PixD. This sequential process provides clues toward a general regulation mechanism of T4P system, which might be essentially common between archaella and other secretion apparatuses.
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Salamé, Elige, Stefano Brizzolara, Marta Rodriguez, Matteo Iob, Pietro Tonutti, and Benedetto Ruperti. "Ethanol fermentation- and ethylene physiology-related gene expression profiles in Red Delicious apples stored under variable hypoxic conditions and protocols." Advances in Horticultural Science 37, no. 1 (March 13, 2023): 89–99. http://dx.doi.org/10.36253/ahsc-14180.
Повний текст джерелаАнотація:
Dynamic Controlled Atmosphere (DCA) is beneficial in maintaining specific quality parameters but, due to the extreme oxygen levels applied, can cause adverse effects on the fruit by inducing excessive anaerobic metabolism and the production of off-flavors. The metabolic adaptation and responses of apples (Malus domestica Borkh.) cv. Red Delicious to static or dynamic oxygen concentrations (0.3 and 0.8%, with sequential shifts) during cold storage for 7 months were studied by monitoring quality parameters and the expression of genes involved in sugar, fermentative metabolism, and ethylene physiology. Ethanol content reached the highest levels (around 400 mg/kg FW) under 0.3% oxygen concentration and fruit firmness appeared to be reduced in samples accumulating the highest levels of ethanol. Oxygen switch was effective in reducing the ethanol concentrations with timing-dependent variable effects. The expression of fermentative (alcohol dehydrogenase, lactate dehydrogenase, pyruvate decarboxylase) and sugar metabolism (β-amylase; phosphofructokinase; sucrose synthase) genes resulted to be differently affected by the hypoxic conditions imposed, in particular during the early stages of storage. Sucrose synthase expression appeared to be highly sensitive to changes in low oxygen concentration. Ethylene biosynthesis (ACC synthase and oxidase) genes showed marked differences in their expression in relation to the static and dynamic protocols and the hypoxic conditions, as well as six Ethylene Responsive Factors (ERF) genes, some of them possibly involved in the oxygen sensing mechanism operating in fruit tissues.
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Guillen-Climent, M. L., H. Mas, A. Fernández-Landa, N. Algeet-Abarquero, and J. L. Tomé. "Uso de imágenes hiperespectrales para la predicción del marchitamiento de Pinus halepensis (Mill.) en el bosque mediterráneo." Revista de Teledetección, no. 55 (June 23, 2020): 59. http://dx.doi.org/10.4995/raet.2020.13289.
Повний текст джерелаАнотація:
<p>The increasing negative effects of climate change and the emergence of invasive species in forests around the world require the development of innovative methods to monitor and quantitatively measure the health status of woodlands. These effects are especially notable in the Mediterranean area, where the decline of stands due to recurrent droughts has increased the damage caused by secondary pests whose populations would otherwise be in balance. Remote sensing technologies allow us to work on large surfaces with reasonable precision. In particular, new spectral indices obtained from high-resolution hyperspectral and thermal images have been shown to be good predictors for the early detection of physiological changes related to diseases. In this pilot study developed in a stand of Pinus halepensis in the Comunitat Valenciana, a controlled simulation of a decay is carried out by means of sequential girdling of trees, making a subsequent field monitoring of the caused decay. Through a hyperspectral camera, the spectral information of each of these trees is analyzed in relation to their discoloration and state of observed decay. The proposed methodology allows the detection of affected trees three months before the appearance of visual symptoms, obtaining a precision higher than 0.9 with Random Forest and Support Vector Machine classifiers. The vegetation indices with better results were PRI, VGO1, VGO2, GM1 and OSAVI. This pilot study allows us to think that some of these indices can be used in the early detection of general pine wilt and, therefore, have application in the monitoring of the main threats to European forests, borer pests or quarantine organisms such as <em>Bursaphelenchus xylophilus.</em></p>
Дисертації з теми "Sequential controlled sensing"
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Narayanaprasad, Karthik Periyapattana. "Sequential Controlled Sensing to Detect an Anomalous Process." Thesis, 2021. https://etd.iisc.ac.in/handle/2005/5514.
Повний текст джерелаАнотація:
In this thesis, we study the problem of identifying an anomalous arm in a multi-armed bandit as quickly as possible, subject to an upper bound on the error probability. Also known as odd arm identification, this problem falls within the class of optimal stopping problems in decision theory and can be embedded within the framework of active sequential hypothesis testing. Prior works on odd arm identification dealt with independent and identically distributed observations from each arm. We provide the first known extension to the case of Markov observations from each arm. Our analysis and results are in the asymptotic regime of vanishing error probability.
We associate with each arm an ergodic discrete time Markov process that evolves on a common, finite state space. The notion of anomaly is that the transition probability matrix (TPM) of the Markov process of one of the arms (the {\em odd arm}) is some $P_{1}$, and that of each non-odd arm is a different $P_{2}$, $P_{2}\neq P_{1}$. A learning agent whose goal it is to find the odd arm samples the arms sequentially, one at any given time, and observes the state of the Markov process of the sampled arm. The Markov processes of the unobserved arms may either remain frozen at their last observed states until their next sampling instant ({\em rested arms}) or continue to undergo state evolution ({\em restless arms}). The TPMs $P_{1}$ and $P_{2}$ may be known to the learning agent beforehand or unknown. We analyse the following cases: (a) rested arms with TPMs unknown, (b) restless arms with TPMs known, and (c) restless arms with TPMs unknown. For each of these cases, we first present an asymptotic lower bound on the {\color{black} growth rate of the }expected time required to find the odd arm, and subsequently devise a sequential arm selection policy which we show achieves the lower bound and is therefore asymptotically optimal.
A key ingredient in our analysis of the setting of rested arms is the observation that for the Markov process of each arm, the long term fraction of entries into a state is equal to the long term fraction of exits from the state (global balance). When the arms are restless, it is necessary for the learning agent to keep track of the time since each arm was last sampled (arm's {\em delay}) and the state of each arm when it was last sampled (arm's {\em last observed state}). We show that the arm delays and the last observed states form a controlled Markov process which is ergodic under any stationary arm selection policy that picks each arm with a strictly positive probability. Our approach of considering the delays and the last observed states of all the arms jointly offers a global perspective of the arms and serves as a `lift' from the local perspective of dealing with the delay and the last observed state of each arm separately, one that is suggested by the prior works. Lastly, when the TPMs are unknown and have to be estimated along the way, it is important to ensure that the estimates converge almost surely to their true values asymptotically, i.e., the system is {\em identifiable}. We show identifiability follows from the ergodic theorem in the rested case, and provide sufficient conditions for it in the restless case.Department of Science and Technology, Ministry of Human Resource Development, Center for Networked Intelligence, Robert Bosch Center for Cyber-Physical Systems
Тези доповідей конференцій з теми "Sequential controlled sensing"
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Atia, George, and Shuchin Aeron. "Controlled sensing for sequential estimation." In 2013 IEEE Global Conference on Signal and Information Processing (GlobalSIP). IEEE, 2013. http://dx.doi.org/10.1109/globalsip.2013.6736831.
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Atia, George K., and Venugopal V. Veeravalli. "Controlled sensing for sequential multihypothesis testing." In 2012 IEEE International Symposium on Information Theory - ISIT. IEEE, 2012. http://dx.doi.org/10.1109/isit.2012.6283841.
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Nitinawarat, Sirin, and Venugopal V. Veeravalli. "Controlled sensing for sequential multihypothesis testing with non-uniform sensing cost." In 2013 Asilomar Conference on Signals, Systems and Computers. IEEE, 2013. http://dx.doi.org/10.1109/acssc.2013.6810462.
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McEver, Mark, and Donald J. Leo. "Autonomous Vibration Suppression Using On-Line Pole-Zero Identification." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-1731.
Повний текст джерелаАнотація:
Abstract An on-line identification and control algorithm is developed based on the properties of collocated sensing and actuation. The feedback control law consists of second-order compensators that achieve equivalent damping in both the filter dynamics and resonant structural dynamics, thus maximizing the damping in the structure and controller. Optimal design of the feedback compensator is obtained using a pole placement algorithm applied to a single, undamped resonant mode. Numerical analysis indicates that multiple modes and structural damping do not appreciably change the damping achieved using the optimal parameters. The pole placement analysis demonstrates that only the pole-zero spacing and DC gain of the collocated transfer function are required to choose the optimal parameters. An on-line identification procedure is developed that sequentially determines the DC gain and pole-zero spacing and automatically designs the feedback compensator. This forms the basis for the autonomous control algorithm. Experimental results on a flexible beam demonstrate that the procedure can accurately identify the pole-zero spacing and automatically design the feedback compensator. A fivefold increase in damping is achieved in the first mode and a twofold increase in damping is achieved in the second mode. Discrepancies between predicted and measured damping are attributed to phase lags due to signal conditioning and low-pass filtering of the sensor signal.
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Nguyen, Mary-Anne, and Stephen A. Sarles. "Microfluidic Generation, Encapsulation and Characterization of Asymmetric Droplet Interface Bilayers." In ASME 2016 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/smasis2016-9034.
Повний текст джерелаАнотація:
Our research focuses on creating smart materials that utilize synthetic cell membranes assembled at liquid interfaces for autonomic sensing, actuation, and energy conversion. Unlike single membrane assemblies, systems featuring many membranes have the potential to offer multi-functionality, greater transduction sensitivity, and even emergent behaviors in response to environmental stimuli, similar to living tissue, which utilizes networks of highly packed cells to accomplish tasks. Here, we present for the first time a novel microfluidic platform capable of generating a stream of alternating droplet compositions, i.e. A-B-A-B, and sequentially capturing these droplets in precise locations to enable the spontaneous formation of synthetic lipid bilayers between droplets of different compositions (i.e. A and B) in an enclosed substrate. This platform preserves a key feature of the droplet interface bilayer (DIB) method, which allows asymmetric conditions within and across the membrane to be prescribed by simply using droplets containing different species. In this work, we demonstrate the ability to assemble bilayers consisting of asymmetric lipid compositions and, separately, show that alternating droplets containing the same lipid type can also be used to control the direction of ion channel insertion. In the first study, A and B droplet types contain liposomes comprised of different lipid types, which are used to establish an asymmetric composition of the leaflets that make up the lipid bilayer. This asymmetry results in a dc, non-zero membrane potential, which we measure via membrane capacitance versus bias voltage. In the second study, alamethicin peptides are included in only one of the droplet types, which enable voltage-dependent insertion to occur only at one polarity. Cyclic voltammetry measurements are performed to confirm the direction of insertion of alamethicin channels in bilayers. Also, these results show the ability to perform simultaneously electrical measurements on multiple DIB, which increases the experimental capacity and efficiency of a microfluidic approach. The ability to produce alternating droplets in a high throughput manner with electrical access provides a system to investigate the effects of lipid asymmetry on the function of membrane proteins in a controlled model system.