Статті в журналах: "Sephin1"

1

Ruiz, Asier, Jone Zuazo, Carolina Ortiz-Sanz, Celia Luchena, Carlos Matute, and Elena Alberdi. "Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response." International Journal of Molecular Sciences 21, no. 17 (August 24, 2020): 6088. http://dx.doi.org/10.3390/ijms21176088.

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Sephin1 is a derivative of guanabenz that inhibits the dephosphorylation of the eukaryotic initiation factor 2 alpha (eIF2α) and therefore may enhance the integrated stress response (ISR), an adaptive mechanism against different cellular stresses, such as accumulation of misfolded proteins. Unlike guanabenz, Sephin1 provides neuroprotection without adverse effects on the α2-adrenergic system and therefore it is considered a promising pharmacological therapeutic tool. Here, we have studied the effects of Sephin1 on N-methyl-D-aspartic acid (NMDA) receptor signaling which may modulate the ISR and contribute to excitotoxic neuronal loss in several neurodegenerative conditions. Time-course analysis of peIF2α levels after NMDA receptor overactivation showed a delayed dephosphorylation that occurred in the absence of activating transcription factor 4 (ATF4) and therefore independently of the ISR, in contrast to that observed during endoplasmic reticulum (ER) stress induced by tunicamycin and thapsigargin. Similar to guanabenz, Sephin1 completely blocked NMDA-induced neuronal death and was ineffective against AMPA-induced excitotoxicity, whereas it did not protect from experimental ER stress. Interestingly, both guanabenz and Sephin1 partially but significantly reduced NMDA-induced cytosolic Ca2+ increase, leading to a complete inhibition of subsequent calpain activation. We conclude that Sephin1 and guanabenz share common strong anti-excitotoxic properties with therapeutic potential unrelated to the ISR.

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2

Crespillo-Casado, Ana, Zander Claes, Meng S. Choy, Wolfgang Peti, Mathieu Bollen та David Ron. "A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2α". Journal of Biological Chemistry 293, № 20 (4 квітня 2018): 7766–76. http://dx.doi.org/10.1074/jbc.ra118.002325.

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3

Thapa, Simrika, Dalia H. Abdelaziz, Basant A. Abdulrahman, and Hermann M. Schatzl. "Sephin1 Reduces Prion Infection in Prion-Infected Cells and Animal Model." Molecular Neurobiology 57, no. 5 (January 24, 2020): 2206–19. http://dx.doi.org/10.1007/s12035-020-01880-y.

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4

Chen, Yanan, Joseph R. Podojil, Rejani B. Kunjamma, Joshua Jones, Molly Weiner, Wensheng Lin, Stephen D. Miller, and Brian Popko. "Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis." Brain 142, no. 2 (January 17, 2019): 344–61. http://dx.doi.org/10.1093/brain/awy322.

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5

Callejo, Gerard, Luke A. Pattison, Jack C. Greenhalgh, Sampurna Chakrabarti, Evangelia Andreopoulou, James R. F. Hockley, Ewan St John Smith, and Taufiq Rahman. "In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3." Biochemical Pharmacology 174 (April 2020): 113834. http://dx.doi.org/10.1016/j.bcp.2020.113834.

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6

Maltsev, Alexander V., Anna B. Nikiforova, Natalia V. Bal та Pavel M. Balaban. "Amyloid Aβ25-35 Aggregates Say ‘NO’ to Long-Term Potentiation in the Hippocampus through Activation of Stress-Induced Phosphatase 1 and Mitochondrial Na+/Ca2+ Exchanger". International Journal of Molecular Sciences 23, № 19 (6 жовтня 2022): 11848. http://dx.doi.org/10.3390/ijms231911848.

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The search for strategies for strengthening the synaptic efficiency in Aβ25-35-treated slices is a challenge for the compensation of amyloidosis-related pathologies. Here, we used the recording of field excitatory postsynaptic potentials (fEPSPs), nitric oxide (NO) imaging, measurements of serine/threonine protein phosphatase (STPP) activity, and the detection of the functional mitochondrial parameters in suspension of brain mitochondria to study the Aβ25-35-associated signaling in the hippocampus. Aβ25-35 aggregates shifted the kinase–phosphatase balance during the long-term potentiation (LTP) induction in the enhancement of STPP activity. The PP1/PP2A inhibitor, okadaic acid, but not the PP2B blocker, cyclosporin A, prevented Aβ25-35-dependent LTP suppression for both simultaneous and delayed enzyme blockade protocols. STPP activity in the Aβ25-35-treated slices was upregulated, which is reverted relative to the control values in the presence of PP1/PP2A but not in the presence of the PP2B blocker. A selective inhibitor of stress-induced PP1α, sephin1, but not of the PP2A blocker, cantharidin, is crucial for Aβ25-35-mediated LTP suppression prevention. A mitochondrial Na+/Ca2+ exchanger (mNCX) blocker, CGP37157, also attenuated the Aβ25-35-induced LTP decline. Aβ25-35 aggregates did not change the mitochondrial transmembrane potential or reactive oxygen species (ROS) production but affected the ion transport and Ca2+-dependent swelling of organelles. The staining of hippocampal slices with NO-sensitive fluorescence dye, DAF-FM, showed stimulation of the NO production in the Aβ25-35-pretreated slices at the dendrite-containing regions of CA1 and CA3, in the dentate gyrus (DG), and in the CA1/DG somata. NO scavenger, PTIO, or nNOS blockade by selective inhibitor 3Br-7NI partly restored the Aβ25-35-induced LTP decline. Thus, hippocampal NO production could be another marker for the impairment of synaptic plasticity in amyloidosis-related states, and kinase–phosphatase balance management could be a promising strategy for the compensation of Aβ25-35-driven deteriorations.

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7

BRAILOVSKY, HARRY, and ERNESTO BARRERA. "Illustrated key to the species in the genus Sephina (Hemiptera: Heteroptera: Coreidae: Coreinae: Spartocerini), with descriptions of three new species and new distributional records." Zootaxa 5048, no. 1 (October 5, 2021): 77–98. http://dx.doi.org/10.11646/zootaxa.5048.1.4.

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Three new species of Sephina Amyot and Serville 1843, are described: S. crassa from Ecuador, S. effrena from Colombia and S. ornata from Panama. A key to the 27 known species and photographs of the dorsal habitus are included. Also included are photographs of the male genital capsule of S. vinula Stål 1862, and parameres of S. indierae Wolcott 1924 and S. vinula. New distributional records for S. dorsalis (White 1842), S. esquivelae Brailovsky & Sánchez 1983, S. faceta Brailovsky 2001, S. formosa (Dallas 1852), S. geniculata Distant 1881, S. limbata Stål 1862, S. nigripes Schmidt 1907, S. pagella Brailovsky & Sánchez 1983, S. pubera (Erichson 1848), S. pustulata (Fabricius 1803), S. rogersi Distant 1881, S. subulata Brailovsky & Sánchez 1983, and S. vinula are included. Sephina excellens Schmidt, 1907 is synonymized under S. pubera (Erichson 1848). The synonymy of Sephina grayi Van Duzee, 1909 under S. gundlachi (Guérin-Méneville 1857) is here corroborated.

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8

Jung, Jisu, Yoomin Kim, Jiwoon Na, Lu Qiao, Jeyoung Bang, Dongin Kwon, Tack-Jin Yoo, et al. "Constitutive Oxidative Stress by SEPHS1 Deficiency Induces Endothelial Cell Dysfunction." International Journal of Molecular Sciences 22, no. 21 (October 28, 2021): 11646. http://dx.doi.org/10.3390/ijms222111646.

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The primary function of selenophosphate synthetase (SEPHS) is to catalyze the synthesis of selenophosphate that serves as a selenium donor during selenocysteine synthesis. In eukaryotes, there are two isoforms of SEPHS (SEPHS1 and SEPHS2). Between these two isoforms, only SEPHS2 is known to contain selenophosphate synthesis activity. To examine the function of SEPHS1 in endothelial cells, we introduced targeted null mutations to the gene for SEPHS1, Sephs1, in cultured mouse 2H11 endothelial cells. SEPHS1 deficiency in 2H11 cells resulted in the accumulation of superoxide and lipid peroxide, and reduction in nitric oxide. Superoxide accumulation in Sephs1-knockout 2H11 cells is due to the induction of xanthine oxidase and NADPH oxidase activity, and due to the decrease in superoxide dismutase 1 (SOD1) and 3 (SOD3). Superoxide accumulation in 2H11 cells also led to the inhibition of cell proliferation and angiogenic tube formation. Sephs1-knockout cells were arrested at G2/M phase and showed increased gamma H2AX foci. Angiogenic dysfunction in Sephs1-knockout cells is mediated by a reduction in nitric oxide and an increase in ROS. This study shows for the first time that superoxide was accumulated by SEPHS1 deficiency, leading to cell dysfunction through DNA damage and inhibition of cell proliferation.

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9

Bang, Jeyoung, Minguk Han, Tack-Jin Yoo, Lu Qiao, Jisu Jung, Jiwoon Na, Bradley A. Carlson, et al. "Identification of Signaling Pathways for Early Embryonic Lethality and Developmental Retardation in Sephs1−/− Mice." International Journal of Molecular Sciences 22, no. 21 (October 28, 2021): 11647. http://dx.doi.org/10.3390/ijms222111647.

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Selenophosphate synthetase 1 (SEPHS1) plays an essential role in cell growth and survival. However, the underlying molecular mechanisms remain unclear. In the present study, the pathways regulated by SEPHS1 during gastrulation were determined by bioinformatical analyses and experimental verification using systemic knockout mice targeting Sephs1. We found that the coagulation system and retinoic acid signaling were most highly affected by SEPHS1 deficiency throughout gastrulation. Gene expression patterns of altered embryo morphogenesis and inhibition of Wnt signaling were predicted with high probability at E6.5. These predictions were verified by structural abnormalities in the dermal layer of Sephs1−/− embryos. At E7.5, organogenesis and activation of prolactin signaling were predicted to be affected by Sephs1 knockout. Delay of head fold formation was observed in the Sephs1−/− embryos. At E8.5, gene expression associated with organ development and insulin-like growth hormone signaling that regulates organ growth during development was altered. Consistent with these observations, various morphological abnormalities of organs and axial rotation failure were observed. We also found that the gene sets related to redox homeostasis and apoptosis were gradually enriched in a time-dependent manner until E8.5. However, DNA damage and apoptosis markers were detected only when the Sephs1−/− embryos aged to E9.5. Our results suggest that SEPHS1 deficiency causes a gradual increase of oxidative stress which changes signaling pathways during gastrulation, and afterwards leads to apoptosis.

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10

Varol, Marie-Christine Bornes. "Haïm Vidal Sephiha (1923 – 2019)." Tsafon, no. 79 (July 1, 2020): 181–83. http://dx.doi.org/10.4000/tsafon.2993.

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11

Pasaribu, Aria Masdiana. "Pengukuran Kinerja Perusahaan Dengan Konsep Balance Scorecard (Studi Kasus CV. Sephine Eta Carinae)." Jurnal Wira Ekonomi Mikroskil 8, no. 1 (April 26, 2018): 93–102. http://dx.doi.org/10.55601/jwem.v8i1.561.

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Tujuan pada penelitian ini adalah untuk mengetahui pengukuran kinerja perusahaan jika diukur dengan metode balance scorecard dalam perspektif keuangan, perspektif proses bisnis internal dan perspektif pembelajaran dan pertumbuhan. Penelitian ini menggunakan metode penelitian deskriptif karena dalam pelaksanaannya meliputi data, analisis dan interpretasi tentang arti dan data yang diperoleh selain itu juga membicarakan kemungkinan pemecahan masalah yang actual dengan mendeskripsikan, mencatat, dan menganalisis kondisi perusahaan. Dalam penelitian ini, CV.Sephin Eta Carinae digunakan sebagai objek penelitian untuk mengetahui system pengukuran balance scorecard. Hasil penelitian ini menunjukkan pada perspektif keuangan ini menunjukkan kinerja perusahaan semakin baik. Pada perspektif proses bisnis internal dalam CV.Sephine Eta Carinae proses inovasi akan terus dikemabangkan oleh para karyawannya. Pada perspektif pembelajaran dan pertumbuhan perusahaan mengalami kenaikan. Penerapan balance scorecard di CV.Sephine Eta Carinae di mungkinkan dengan adanya faktor?¢â?¬â?? faktor pendukung, seperti pernyataan misi dan strategi yang memadai, motivasi karyawan , lingkungan bisnis yang kompetitif , dan kecakupan data

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12

Medler, John T. "The types of Flatidae (Homoptera) in the Stockholm Museum described by Stat, Melichar, Jacobi and Walker." Insect Systematics & Evolution 17, no. 3 (1986): 323–37. http://dx.doi.org/10.1163/187631286x00251.

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AbstractLectotypes and paralectotypes are designated for species of flatid planthoppers described by StÅl, Melichar, Jacobi and Walker. The location of other syntypes known to exist is given. The genitalia of lectotype males are illustrated. NEW SYNONYMY (junior synonym first), as follows: Colgaroides circumcincta Jacobi = Colgaroides acuminala (Walker); Mesophylla inclinala Melichar = Phylliana serva (Walker); Copsyrna leucophaea StÅl = Bythopsyrna lineoides (Olivier); Hypsiphanta minax Jacobi = Euphanta munda (Walker); Euphanta obscura Jacobi = Euryphantia tristis (Kirkaldy); Idume plicala Melichar = Idurne deducta (Walker); Phromnia rubescens StÅl = Flatida floccosa (Guérin-Ménèville. NEW COMBINATIONS (previous combination first), as follows: Poeciloptera cereris StÅl = Cromna sinensis (Walker); Paratella fusconigra Melichar = Sephena fusconigra (Melichar); Phyllyphanla hyalinata StÅl= Colgar peracuta (Walker); Paratella modesta Melichar = Sephena modesta (Melichar); Delostenopium rubripes Jacobi = Euphanta rubripes (Jacobi); Microflata stictica Melichar = Mimophantia sliclica (Melichar). NEW STATUS: Melicharia alba (Melichar) not a varitey of Melicharia deducta (Melichar); Lawana inornata (Melichar) not a variety of Lawana candida (Fabricius); Cerynia maria lutescens Melichar not a variety of Cerynia maria (White); Melicharia pallida (Melichar) not a synonym of Melicharia lactifera (Walker).

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13

Hughes, Bernard. "Barry's ‘The Intelligence Park’." Tempo 60, no. 238 (October 2006): 36–37. http://dx.doi.org/10.1017/s004029820622031x.

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BARRY: The Intelligence Park. Richard Jackson (bass bar), Paul Harhy (ten), Sephen Richardson (bass), Angela Tunstall (sop), Nicholas Clapton (counter-ten), Buddug Verona James (contralto), Almeida Ensemble c. Robert Houlihan. NMC D122

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14

Wikanta, Thamrin, Riyadini Perwita, Prih Sarnianto, and Murdinah Murdinah. "ISOLASI DAN KARAKTERISASI SENYAWA GLIKOSAMINOGLIKAN DARI ORGAN IKAN PARI (Trygon sepfren)." Jurnal Penelitian Perikanan Indonesia 8, no. 6 (March 21, 2017): 11. http://dx.doi.org/10.15578/jppi.8.6.2002.11-20.

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Tulisan ini melaporkarq hasil penelitian tentang isolasi dan karakterisasi senyawaglikosaminoglikan dari beberapa organ ikan pari (Trygon sephen) yang mencakup proses ekstraksi melalui tahapan pencernaan, presipitasi dan pemurnian, serta identifikasi senyawa menggunakan teknik spektrofotometri inframerah, khromatografi cair kinerja tinggi dan elektroforesis.

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15

Gómez Núñez, Nicolás. "La plaza laboral como espacio de legitimación del sociólogo. Apuntes para el caso chileno." Revista Temas Sociológicos, no. 14 (January 25, 2017): 99. http://dx.doi.org/10.29344/07194145.14.245.

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ResumenLo que se encuentra bajo análisis es la estructura posible de las relaciones sociales que logran dotar de poder material y simbólico a los mecanismos de inclusión del sociólogo en el Mercado de Trabajo. El artículo fue presentado en el II Workshop sobre Dependencia Académica: “El desafío de construir Ciencias Sociales autónomas en el Sur”, organizado por la Universidad Nacional de Cuyo de la ciudad de Mendoza en Argentina, el Programa Sur-Sur del Consejo Latinoamericano de Ciencias Sociales, SEPHIS, PIDAAL y SRIIRU, y que se realizó entre el 3 y 6 de noviembre de 2010.Palabras clave: Identidad Profesional, Mecanismos de Legitimación y Mercado LaboralAbstractWhat is under analysis here is the possible structure of social relationships that provide material and symbolic power to inclusive mechanisms of sociologists within the Labour Market. The article was presented at the Second Workshop on Academic dependence: “The challenge of building autonomous Social Sciences in the South”, organized by the Universidad Nacional de Cuyo in Mendoza in Argentina, the South-South Program of the Latin American Council of Social Sciences, SEPHIS, PIDAAL and SRIIRU, which was conducted between the 3rd and 6th of November, 2010.Key words: Professional identity, Legitimating mechanisms and Labor Market

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16

Gómez Núñez, Nicolás. "La plaza laboral como espacio de legitimación del sociólogo. Apuntes para el caso chileno." Revista Temas Sociológicos, no. 14 (January 25, 2017): 99. http://dx.doi.org/10.29344/07196458.14.245.

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ResumenLo que se encuentra bajo análisis es la estructura posible de las relaciones sociales que logran dotar de poder material y simbólico a los mecanismos de inclusión del sociólogo en el Mercado de Trabajo. El artículo fue presentado en el II Workshop sobre Dependencia Académica: “El desafío de construir Ciencias Sociales autónomas en el Sur”, organizado por la Universidad Nacional de Cuyo de la ciudad de Mendoza en Argentina, el Programa Sur-Sur del Consejo Latinoamericano de Ciencias Sociales, SEPHIS, PIDAAL y SRIIRU, y que se realizó entre el 3 y 6 de noviembre de 2010.Palabras clave: Identidad Profesional, Mecanismos de Legitimación y Mercado LaboralAbstractWhat is under analysis here is the possible structure of social relationships that provide material and symbolic power to inclusive mechanisms of sociologists within the Labour Market. The article was presented at the Second Workshop on Academic dependence: “The challenge of building autonomous Social Sciences in the South”, organized by the Universidad Nacional de Cuyo in Mendoza in Argentina, the South-South Program of the Latin American Council of Social Sciences, SEPHIS, PIDAAL and SRIIRU, which was conducted between the 3rd and 6th of November, 2010.Key words: Professional identity, Legitimating mechanisms and Labor Market

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17

Rodríguez-Mozos, J. M., and A. Moya. "Statistical-likelihood Exo-Planetary Habitability Index (SEPHI)." Monthly Notices of the Royal Astronomical Society 471, no. 4 (August 28, 2017): 4628–36. http://dx.doi.org/10.1093/mnras/stx1910.

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18

LEE, YOUNG JUNE. "Apaturinae (Lepidoptera: Nymphalidae) from the Korean Peninsula: Synonymic Lists and Keys to Tribes, Genera and Species." Zootaxa 2169, no. 1 (July 28, 2009): 1–20. http://dx.doi.org/10.11646/zootaxa.2169.1.1.

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This paper provides keys to tribes, genera and species and synonymic lists for the 12 butterfly species belonging to eight genera of Apaturinae (Lepidoptera: Nymphalidae) from the Korean Peninsula: Apatura ilia (Denis and Schiffermüller), Apatura metis Freyer, Apatura iris (Linnaeus), Hestina japonica (Felder and Felder), Hestina assimilis (Linnaeus), Sasakia charonda (Hewitson), Mimathyma schrenckii (Ménétriès), Mimathyma nycteis (Ménétriès), Sephisa princeps (Fixsen), Chitoria ulupi (Doherty), Dilipa fenestra (Leech) and Dichorragia nesimachus (Doyère). Species accounts include brief summaries of each taxon’s biology, taxonomy and life history. The distributional ranges of the Hestina persimilis species complex are discussed and illustrated.

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19

Bang, Jeyoung, Donghyun Kang, Jisu Jung, Tack-Jin Yoo, Myoung Sup Shim, Vadim N. Gladyshev, Petra A. Tsuji, Dolph L. Hatfield, Jin-Hong Kim, and Byeong Jae Lee. "SEPHS1: Its evolution, function and roles in development and diseases." Archives of Biochemistry and Biophysics 730 (November 2022): 109426. http://dx.doi.org/10.1016/j.abb.2022.109426.

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20

Herrero, E. V., J. P. Mitchell, W. T. Lanini, S. R. Temple, E. M. Miyao, R. D. Morse, and E. Campiglia. "Use of Cover Crop Mulches in a No-till Furrow-irrigated Processing Tomato Production System." HortTechnology 11, no. 1 (January 2001): 43–48. http://dx.doi.org/10.21273/horttech.11.1.43.

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No-till processing tomato (Lycopersicum esculentum Mill.) production in four winter cover crop-derived mulches was evaluated in 1997 and 1998 in Five Points, Calif. The effectiveness of two medics, `Sava' snail medic (Medicago scutellata Mill.) (sava), and `Sephi' barrel medic (Medicago truncatula Gaertn.) (sephi), and two cereal/legume cover crop mixtures, triticale/`Lana' woolypod vetch (X Triticosecale Wittm./Vicia dasycarpa Ten.) (triticale/vetch) and rye/`Lana' woolypod vetch (Secale cereale L./V. dasycarpa) (rye/vetch), was compared with two conventionally tilled fallow controls (with and without herbicide) (fallow+h and fallow-h) in suppressing weeds and maintaining yields with reduced fertilizer inputs. The comparison was conducted as a split plot, with three N fertilization rates (0, 100, and 200 lb/acre; 0, 112, and 224 kg·ha-1) as main plots and cover crops and fallow controls as subplots. Tomato seedlings were transplanted 3 weeks after the cover crops had been mowed and sprayed with herbicide. There were no significant differences in weed cover in the no-till cover crop treatments relative to the fallow controls in 1997. Early season weed suppression in rye/vetch and triticale/vetch plots was similar to herbicide-treated fallow (fallow+h) in 1998, however, later in the 1998 season weed suppression was best in the fallow+h. Tissue N was highest in the fallow treatments in both 1997 and 1998. Yields were highest in the triticale/vetch and fallow and lowest in sephi treatments in 1997, but there were no differences among treatments in 1998. These results demonstrate the feasibility of no-till mulch production of furrow irrigated processing tomatoes and identify opportunities for further optimization of the system.

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Talaie*, Alireza, Vali Rabiei, and Ali Ebadi. "Physiological and Morphological Responses of Some Iranian Commercial Grapevine Cultivars to Water Stress." HortScience 39, no. 4 (July 2004): 857C—857. http://dx.doi.org/10.21273/hortsci.39.4.857c.

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Grapevine under arid and semi-arid are subjected to low soil water availability, accompanied by high levels of temperature and severe transpiration in the summer period. In spite of their deep root system, severe water stress may occur during that period. Therefore, study of morphological and physiological responses of grapevine cultivars to water stress, especially during the different phenological stages, are necessary. The effect of water deficit stress on morphological and physiological responses of four Iranian grapevine cultivars (Vitis vinifera L. cvs. Bidaneh Sephid, Yaghooti Shiraz, Khoshnav, and Siaveh) were studied. This investigation was conducted as a factorial experiment in a complete randomized block design with four replications. In this study, 1-year-old own rooted vines were planted outdoor in plastic bags. Water stress was begun 115 days after bud break and contained for 2 months. Some vegetative and biochemical characters of leaves were evaluated; photosynthesis and gas exchange was measured. The results of analysis of variance indicated that water deficit stress decreased total dry weight, root dry weight, leaf area, non soluble carbohydrate concentration, and chlorophyll content. The reduction of leaf area in `Yaghooti Shiraz' and total dry weight and root dry weight in `Bidaneh Sephid' were higher than two other cultivars. Under water deficit stress condition, the soluble carbohydrate concentration and proline content in grapevine cultivars increased. Net photosynthesis and gas exchange rate were markedly reduced in water deficit stressed vines.

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22

Lodge, GM. "The effects of native grass cover, species, herbicide and sowing method on legume establishment on the northern slopes of New South Wales." Australian Journal of Experimental Agriculture 31, no. 4 (1991): 485. http://dx.doi.org/10.1071/ea9910485.

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The effects of sowing method (direct drilling or broadcasting), level of cover of native grass and pre-sowing herbicide application on pasture legume introduction were evaluated from 1984 to 1987 at a low elevation (425 m) site on the Northern Slopes of New South Wales. Two perennial (Medicago sativa cv. CUF101 and Onobrychis viciijolia cv. Eski) and 3 annual legumes (Trifolium subterraneum ssp. brachycalycinum cv. Clare; M. truncatula cv. Sephi; Vicia villosa ssp. dasycarpa cv. Namoi) were sown each year from 1984 to 1986. Seedling establishment was measured 3-4 months after sowing, and where possible, the dry matter yields of the sown legume were also estimated. Seedling regeneration was measured in 1987 and the yield of legumes sown in 1985 was determined in 1986. All species failed to establish under the dry conditions experienced in 1984. In subsequent years seedling numbers of the annuals were higher than those of the perennials. Direct drilling increased establishment of all species compared with broadcasting. The provision of a large amount of cover by the resident native grasses (4.6-7 t/ha of dry matter, 0.6-0.7 In in height) also substantially increased seedling establishment in cvv. Clare, Sephi and CUFlO1. None of the treatments used were successful in establishing cv. Eski. Herbicide application prior to sowing did not significantly affect seedling numbers in the establishment year but resulted in higher numbers of seedlings regenerating in subsequent years, particularly in cv. Sephi. Seedling regeneration of the annuals was also increased (P<0.05) by direct drilling into moderate or high levels of vegetative cover. Dry matter yields of all sown species except cv. Namoi were low, and the environment was difficult for legume survival and production. This was attributed mainly to the variable rainfall that occurs at this low elevation, while for lucerne high summer temperatures probably affected its performance.

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LAST, PETER R., B. MABEL MANJAJI, and GORDON K. YEARSLEY. "Pastinachus solocirostris sp. nov., a new species of Stingray (Elasmobranchii: Myliobatiformes) from the Indo-Malay Archipelago." Zootaxa 1040, no. 1 (August 23, 2005): 1. http://dx.doi.org/10.11646/zootaxa.1040.1.1.

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A new stingray, Pastinachus solocirostris sp. nov., is described from material collected from Malaysian Borneo and Indonesia. It differs from the only other recognised member of the genus, P. sephen, in having a smaller adult size, more elongate disc and head, longer and more acute snout covered to its apex with enlarged denticles, more posteriorly located sting, longer and more slender ventral cutaneous fold, enlarged pearl-shaped nuchal thorns, and fewer pectoral-fin radials and vertebrae. It appears to occur primarily in estuaries and turbid coastal marine habitats off Borneo and Sumatra.

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Jameleddine, Mouna, Nabil Harzallah, Jaafar Chemli, Hela Grati, Marie Christine Jebali, and Chokri Hamouda. "PP101 Development Process Of The Economic Guidelines In Tunisia." International Journal of Technology Assessment in Health Care 38, S1 (December 2022): S73—S74. http://dx.doi.org/10.1017/s0266462322002276.

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IntroductionHealth technology assessment (HTA) has become a critical support to health policy decision-making. The HTA evaluation process requires transparency, formalized processes, clear timelines, and standardization according to international best practice. Tunisia is establishing an HTA-based decision-making system through the National Authority for Accreditation and Assessment in Healthcare (INEAS) to ensure impartiality and fairness in decision-making, which is important for an emerging democracy. INEAS opted for a participatory approach in developing the national health economic guidelines to better engage healthcare sector stakeholders in the HTA process. We aimed to present the main phases of the process used to develop the Tunisian health economic guidelines, the methodological choices for pharmacoeconomic evaluations, and the methodological choices for budget impact analyses.MethodsThe different phases of developing the guidelines were listed and reported.ResultsThe guidelines were developed under a technical cooperation program of the World Health Organization and involved collaboration between the Institut national d’excellence en santé et en services sociaux (INESSS in Quebec, Canada) and INEAS. The first version of the guidelines was drafted following a review of international HTA guidelines and best practice reference books, taking into account the Tunisian healthcare system context. This first draft was discussed in a workshop with the main health system stakeholders and then peer reviewed by international experts. Based on the feedback from experts, a second version was prepared and published on the INEAS website for public consultation. The Union of Innovative Pharmaceutical Research Companies (SEPHIRE), the National Health Insurance Fund (CNAM), and healthcare professionals provided the majority of feedback. The comments provided by SEPHIRE were discussed during a second workshop. The guidelines were revised and updated based on the comments provided and the final version was published in November 2021.ConclusionsINEAS adopted a participatory approach for developing its economic guidelines, which enhanced engagement of the major health system stakeholders in the HTA implementation process in Tunisia.

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Nthoi, Leslie. "Kereke Ya Sephiri: A Study of a Secret Society in Botswana and South Africa." Journal for the Study of Religion 35, no. 1 (July 27, 2022): 1–24. http://dx.doi.org/10.17159/2413-3027/2022/v35n1a6.

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The difference between esotericism and exoterism is unlike the difference between circles and rectangles. It is also not the difference between the size and relevance of a specific body of knowledge in circulation. It is rather the extent of the circulation, acceptance, understanding, and meaning of a particular body of knowledge, philosophy, or worldview, over the spiritual and socio-political life of diverse categories of people in society. The infancy of the academic study of esotericism, as well as its interdisciplinary nature, militate against the crystallization of a universally accepted definition of the term 'esotericism'. The various definitions of the term by researchers consistently relate to their research interests. In line with Faivre's concern with the forms of thought of esoteric movements (Faivre 1996), as well as the preoccupation that Versluis has with gnosis generation in esoteric movements (Versluis n.d), our study of Kereke ya Sephiri in Botswana and South Africa examines a) the cultural and religious contexts in which Frederick Modise, a gnostic in his own right, generated the underlying gnosis of his secret society, and b) the import of the content of this visionary mystical revelation in the spiritual and social lives of members of this secret society1. The study of the Setswana term, Kereke ya Sephiri (church of a secret, referring to a Christian-based secret society), is a study of African esotericism in South Africa and Botswana. The principal academic interest in the study of esotericism lies in our quest to identify the fundamental tenets of the worldviews of the specific esoteric society, the eclectic nature of its philosophy, and how this philosophy relates to the orthodoxy of the day (Christianity in this instance). We do so by concentrating on the form of thinking, engendered by esoteric practices. Esoteric groups do not appear or exist within cultural voids. For this reason, by identifying the eclectic or syncretic nature of the fundamental philosophy (gnosis) of these groups, we trace the cultural influences involved in the emergence and consolidation of these worldviews and philosophies. This study shows that African esotericism is not always antithetic or subversive of dominant or institutionalized Christianity.

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Poernomo, Achmad. "FRACTIONATION OF PROTEASES FROM COWTAIL RAY (Trygon sephen) VISCERA USING POLYACRYLIC ACIDS." Indonesian Fisheries Research Journal 5, no. 1 (June 7, 2017): 61. http://dx.doi.org/10.15578/ifrj.5.1.1999.61-67.

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Poernomo, Achmad. "THE EXTRACTION AND ACTIVITY OF CRUDE ENZYMES FROM COWTAIL RAY (Trygon sephen) VISCERA." Indonesian Fisheries Research Journal 4, no. 1 (June 7, 2017): 39. http://dx.doi.org/10.15578/ifrj.4.1.1998.39-45.

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The viscera are usually wasted in the processing of cowtail ray, although they may contain many valuable substances such as proteolytic enzymes. This study investigates the possibility of using these enzymes to produce fish protein hydrolysates

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Ristia Rahman, Ika, and Athiah Masykuroh. "KARAKTERISTIK DAN NILAI SUN PROTECTING FACTOR (SPF) KITOSAN DARI TULANG SOTONG (Sephia officinalis)." Jurnal Insan Farmasi Indonesia 3, no. 2 (December 28, 2020): 298–306. http://dx.doi.org/10.36387/jifi.v3i2.539.

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Cuttlefish (sepia officinalis) have internal shells commonly called cuttlebones which produce more chitin than shrimp shells and crab skins. The purpose of this study was to determine the characteristics of chitosan from cuttlebone including the degree of deacetylation, water content, solubility, organoleptic test (color, odor, texture) as well as testing the value of chitosan protecting the sun protection factor. Chitosan is made in 3 stages, namely deproteination, demineralization, and deacetylation. Deproteination with 4% NaOH at 100 ° C for 60 minutes. Demineralization at room temperature using 1M HCl solution for 120 minutes. Deacetylation using 50% NaOH concentration at 100 ° C for 60 minutes. Chitosan characterization includes the degree of deacetylation, moisture content, solubility, organoleptic test (color, odor, texture). Testing the value of sun protection factor using a UV-VIS spectrophotometer read at wavelengths from 290 to 320 nm. Characteristics of chitosan produced according to chitosan standards used in industry with a deacetylation rate of 71%, yield 31%, moisture content of 0.93%, soluble in acetic acid2% solution, white odorless and powdery. Chitosan with a concentration of 3% gives the value of sun protecting factor 9 as a potential sunscreen that provides maximum protection power.

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Adday, Thamir K., and Najim R. Khamees. "Praniza (Isopoda: Gnathia) Parasitic on Gills of Arabian carpetshark Chiloscyllium arabicum with Notes of its Occurrence on some Marine Fishes of Iraq." Basrah Journal of Agricultural Sciences 35, no. 1 (March 11, 2022): 132–39. http://dx.doi.org/10.37077/25200860.2022.35.1.11.

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Praniza larvae of Gnathia sp. were reported on the gills of 18 Iraqi sea fish species. Hosts were eight elasmobranchs and 10 teleosts. Cartilaginous hosts belong to four families, with highest mean prevalence was 100% in Pastinachus sephen, while the lowest prevalence was 25% in Gymnura poecilura. Teleost hosts belong to seven families, the highest prevalence was 50% in Rabdosargus haffara and the lowest was 1.6% in Tenualosa ilisha. The higher mean intensity of infection was 12.3 in Chiloscyllium arabicum, and only one in all teleost fish species. Praniza parasite of C. arabicum has long body, concave cephalon, narrowing anteriorly with truncate frontal margin, the compound eyes large, pleotelson triangular, uropods have endopods not extending beyond the end of the pleotelson.

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Semeniuk, Christina A. D., and Lawrence M. Dill. "Cost/benefit analysis of group and solitary resting in the cowtail stingray, Pastinachus sephen." Behavioral Ecology 16, no. 2 (November 3, 2004): 417–26. http://dx.doi.org/10.1093/beheco/ari005.

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Lee, Mi-Ok, and Yee Sook Cho. "The role of selenium-mediated redox signaling by selenophosphate synthetase 1 (SEPHS1) in hESCs." Biochemical and Biophysical Research Communications 520, no. 2 (December 2019): 406–12. http://dx.doi.org/10.1016/j.bbrc.2019.09.123.

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Qiao, Lu, So Hee Dho, Ji Young Kim, and Lark Kyun Kim. "SEPHS1 is dispensable for pluripotency maintenance but indispensable for cardiac differentiation in mouse embryonic stem cells." Biochemical and Biophysical Research Communications 590 (January 2022): 125–31. http://dx.doi.org/10.1016/j.bbrc.2021.12.091.

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Oudouhou, Flore, Bastien Casu, Arnold Steve Dopgwa Puemi, Jurgen Sygusch, and Christian Baron. "Analysis of Novel Interactions between Components of the Selenocysteine Biosynthesis Pathway, SEPHS1, SEPHS2, SEPSECS, and SECp43." Biochemistry 56, no. 17 (April 20, 2017): 2261–70. http://dx.doi.org/10.1021/acs.biochem.6b01116.

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Suprapto, H., S. Kumalaningsih, W. Wignyanto, I. Santoso, and S. Sucipto. "Optimization of stingray (Trygon sephen) smoking to extend shelf life and consumer preferences using response surface methodology." IOP Conference Series: Earth and Environmental Science 733, no. 1 (April 1, 2021): 012114. http://dx.doi.org/10.1088/1755-1315/733/1/012114.

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Suprapto, H., S. Kumalaningsih, W. Wignyanto, I. Santoso, and S. Sucipto. "Chemical and microbial changes of stingray fish (Trygon sephen) during soaking in salt solution before smoking process." Food Research 6, no. 5 (September 9, 2022): 68–75. http://dx.doi.org/10.26656/fr.2017.6(5).445.

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The salting process at a fisherman's level is still traditional and does not yet have a standard for salt concentration and soaking time, thus affecting the freshness and quality of fish for further processing. For this reason, it is necessary to conduct research that can maintain the quality of fish before the smoking process to ensure results can be recommended for fellow fishermen. This research aimed to find the best quality of lowsalted stingray fish (Trygon sephen) treated with different salt solution concentrations and soaking time durations before the smoking process. This study used three levels of salt solution concentration (10%, 20%, and 30% w/v, respectively) as the first factor and soaking time duration (1 hr, 2 hrs, and 3 hrs) as the second factor. Chemical and microbial analyses of samples were performed during treatment to investigate their quality. The results showed that stingray fish soaked in 10% salt solution for 1 hr was the best treatment. In this treatment, the pH, total plate count (TPC), total volatile base nitrogen (TVB-N), and trimethylamine nitrogen (TMA-N) values were 6.92, 4.98×105 CFU/g, 6.12 mg N/100 g, and 5.56 mg N/100 g, respectively. Meanwhile, protein loss in this treatment was 2.66. In conclusion, treatment with 10% salt solution for 1 hr could be used in stingray fish considering that this treatment resulted in good quality with the lowest protein loss. Furthermore, this treatment is used as a reference for the smoking process because the concentration of the salt solution is low and the soaking time duration is short.

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Semeniuk, Christina A. D., and Lawrence M. Dill. "Anti-Predator Benefits of Mixed-Species Groups of Cowtail Stingrays (Pastinachus sephen) and Whiprays (Himantura uarnak) at Rest." Ethology 112, no. 1 (January 2006): 33–43. http://dx.doi.org/10.1111/j.1439-0310.2006.01108.x.

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Rajesh Kumar, Kalainesan, Rathinam Vennila, Shankar Kanchana, Muthuvel Arumugam, and Thangavel Balasubramaniam. "Fibrinogenolytic and anticoagulant activities in the tissue covering the stingers of marine stingrays Dasyatis sephen and Aetobatis narinari." Journal of Thrombosis and Thrombolysis 31, no. 4 (December 17, 2010): 464–71. http://dx.doi.org/10.1007/s11239-010-0537-6.

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Santesmasses, Didac, and Vadim Gladyshev. "Selenocysteine Machinery Primarily Supports TXNRD1 and GPX4 Functions and Together They Are Functionally Linked with SCD and PRDX6." Biomolecules 12, no. 8 (July 28, 2022): 1049. http://dx.doi.org/10.3390/biom12081049.

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The human genome has 25 genes coding for selenocysteine (Sec)-containing proteins, whose synthesis is supported by specialized Sec machinery proteins. Here, we carried out an analysis of the co-essentiality network to identify functional partners of selenoproteins and Sec machinery. One outstanding cluster included all seven known Sec machinery proteins and two critical selenoproteins, GPX4 and TXNRD1. Additionally, these nine genes were further positively associated with PRDX6 and negatively with SCD, linking the latter two genes to the essential role of selenium. We analyzed the essentiality scores of gene knockouts in this cluster across one thousand cancer cell lines and found that Sec metabolism genes are strongly selective for a subset of primary tissues, suggesting that certain cancer cell lineages are particularly dependent on selenium. A separate outstanding cluster included selenophosphate synthetase SEPHS1, which was linked to a group of transcription factors, whereas the remaining selenoproteins were linked neither to these clusters nor among themselves. The data suggest that key components of Sec machinery have already been identified and that their primary role is to support the functions of GPX4 and TXNRD1, with further functional links to PRDX6 and SCD.

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Lake, AWH. "Spotted alfalfa aphid survival and reproduction on annual medics with various levels of aphid resistance." Australian Journal of Agricultural Research 40, no. 1 (1989): 117. http://dx.doi.org/10.1071/ar9890117.

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Annual medics (Medicago spp.) with resistance to spotted alfalfa aphid (Therioaphis trifolii (Monell) fm. maculata) (SAA) are progressively replacing older susceptible cultivars in new sowings in Australian pastures. Six lines and cultivars from the species M. truncatula and M. littoralis with varying degrees of SAA resistance were studied for their effect on SAA survival, development and reproduction.Antibiosis in the form of decreased nymph and adult survival, increased developmental times and decreased nymph production per adult and production rate were detected. In the resistant lines tested, Sephi and 2-243 had very high levels of antibiosis to SAA: sufficient to prevent any nett multiplication of SAA. Two less resistant lines, Parabinga and SA 12591, also had significant antibiosis to SAA compared to the susceptible cultivars Harbinger and Borung, but aphid survival and multiplication were still moderately high. Behavioural patterns suggest antixenosis is insignificant as a resistance mechanism in all these lines in a no-choice situation.

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Lodge, GM. "Seedling emergence and survival of annual pasture legumes in northern New South Wales." Australian Journal of Agricultural Research 47, no. 4 (1996): 559. http://dx.doi.org/10.1071/ar9960559.

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Seedling emergence and survival of 15 annual pasture legumes was studied in the field at Tamworth, northern New South Wales. Emergence was measured in permanent quadrats (0.09 m2) in covered and uncovered areas approximately every 15 days from 30 November 1983 to 30 November 1984. Survival of seedlings was estimated from 15 December 1983 to 31 August 1984, before plants senesced. Emergence was generally highest in summer and autumn following seed set and lowest in winter and spring. Two legumes, Medicago scutellata cv. Sava and Trifolium subterraneum cv. Seaton Park, had high emergence in winter (mid July). Total seedling emergence was highest ( P < 0.05) in covered areas of cv. Seaton Park and uncovered areas of T. hirtum cv. Hykon. All T. subterraneum cultivars, M. minima, Astragalus hamosus cv. Ioman, Vicia villosa cv. Namoi, and M. truncatula cv. Paraggio had higher total emergence in covered compared with uncovered areas. In contrast, total emergence of M. aculeata, M. truncatula cv. Jemalong, Sava, and Hykon was lowest in covered areas. Cover had little effect on the total emergence of M. truncatula cv. Sephi and T. glomeratum. Of the 7700 individual seedlings marked from November 1983 to August 1984, a mean of only 31% (covered) and 41% (uncovered) survived until 31 August 1984. For each emergence time, highest ( P < 0.05) survival rate coincided with the highest (P < 0.05) number of emerged seedlings in 4 of the legumes in covered areas (cv. Namoi, 31 January; cv. Ioman, 31 March; cv. Hykon, 15 April; cv. Sava, 15 July; Table 4) and 9 in uncovered areas (cvv. Nungarin, Seaton Park, and Namoi, 31 January; M. aculeata and cv. Sephi, 28 February; cvv. Jemalong and Ioman, 31 March; T. glomeratum, 15 April; cv. Sava, 15 July). In all other legumes there was no optimum time for emergence, since the highest (P < 0.05) survival rates were associated with seedling survivals <50%. Generally, survival curves with a mortality constant rather than a mortality rate were a better fit ( P < 0.05) for most legumes and times. This implied that these survival curves were determined at the time of recruitment, and declined at a constant rate, despite below-average post-emergence rainfall in May-June. Low rates of survival at times of highest ( P < 0.05) emergence indicated that there may have been some density-dependent regulation in some of the legumes.

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Lodge, G. M., and R. D. B. Whalley. "Fate of annual pasture legumes seeds on a two-way thermo-gradient plate." Rangeland Journal 24, no. 2 (2002): 227. http://dx.doi.org/10.1071/rj02013.

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Effects of diurnally alternating temperatures (5/5–45/45�C) were examined on a two-way thermogradient plate for non-dormant seeds of 14 annual pasture legumes. Seed fates (germination, temperature induced non-viability and temperature induced dormancy) were determined from daily seed counts over a 14-day period on-plate and a further 14 days after removal from the plate. These data clearly demonstrate the existence and extent of seed fates other than germination. Maximum dormancy occurred over a broad range of temperatures for seeds of Trifolium subterraneum L. var. subterraneum (Katzn. et Morley) Zohary and Heller cv. Woogenellup (40/35–30/25�C), Astragalus hamosus L. cv. Ioman (40/25–30/5�C) and Trifolium hirtum All. cv. Hykon (35/30–30/5�C). In contrast, maximum dormancy occurred over a narrow temperature range for Medicago truncatula Gaertn. var. truncatula cv. Paraggio (35/30–30/25�C), M. aculeata Willd. var. inermis (Aschers.) Heyn (30/25 and 30/20�C), and M. minima L. (35/20–35/5�C) seeds. Generally, non-viability was highest in all legumes when temperatures were greater than 35/30�C and not significantly different from the maximum value (100%) at temperatures greater than 40/30�C. At temperatures less than 35/30�C non-viability was less than the maximum (P<0.05) for seeds of all legumes, except M. truncatula cvs. Jemalong and Sephi, M. aculeata, and Vicia villosa ssp. dasycarpa (Ten.) Cav. cv. Namoi. Compared with the other subterranean clover cultivars germination levels T. subterraneum var. brachycalycinum (Katzn. et Morley) Zohary and Heller cv. Clare seeds were not significantly different from the maximum value at higher temperatures. In all annual medics, except M. aculeata germination was not significantly different to the maximum at temperatures greater than 25/20�C, with high germination (P<0.05) occurring at 30/25�C in Jemalong and M. scutellata (L.) Mill cv. Sava and at 30/20�C in Paraggio, Sephi, M. minima and M. polymorpha L. Maximum germination in Ioman and Hykon seeds occurred over a broader temperature range (35/20–15/10�C and 30/20–15/5�C, respectively) than in Namoi (30/15�C and 25/20–25/5�C). Probable implications of these data for field emergence of non-dormant seeds and soil seed reserves are discussed.

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Manna, Sanjukta, and Buddhadeb Manna. "A New Genus of the Tetraphyllidean Cestodes from Dasyatis sephen Forsskal, 1775 Captured from Digha Coastal Water, Bay of Bengal, India." Proceedings of the Zoological Society 71, no. 4 (November 18, 2016): 305–12. http://dx.doi.org/10.1007/s12595-016-0190-y.

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Maleki, Loghman, Masoumeh Malek, and Harry W. Palm. "Two new species of Acanthobothrium (Tetraphyllidea: Onchobothriidae) from Pastinachus cf. sephen (Myliobatiformes: Dasyatidae) from the Persian Gulf and Gulf of Oman." Folia Parasitologica 60, no. 5 (November 27, 2013): 448–56. http://dx.doi.org/10.14411/fp.2013.048.

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HASELI, MOHAMMAD, MASOUMEH MALEK, and HARRY WILHELM PALM. "Trypanorhynch cestodes of elasmobranchs from the Persian Gulf." Zootaxa 2492, no. 1 (June 2, 2010): 28. http://dx.doi.org/10.11646/zootaxa.2492.1.2.

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The first large scale study of trypanorhynch cestodes of elasmobranchs from the Persian Gulf was carried out during November to December 2007. A total of 194 elasmobranch specimens belonging to six families and 15 species was infested with the following cestodes, most representing new locality and 23 new host records: Kotorella pronosoma (Stossich, 1901), Kotorella sp. and Nybelinia spp. from the stomach, and Pterobothrium lesteri Campbell & Beveridge, 1996, Pseudogrillotia perelica (Shuler, 1938), Callitetrarhynchus gracilis Pintner, 1931, Proemotobothrium southwelli Beveridge & Campbell, 2001, Otobothrium carcharidis (Shipley & Hornell, 1906), Otobothrium sp., Halysiorhynchus macrocephalus (Shipley & Hornell, 1906), Trygonicola macropora (Shipley & Hornell, 1906), Eutetrarhynchus platycephali Palm, 2004, Eutetrarhynchus sp., Oncomegoides celatus Beveridge & Campbell, 2005, Parachristianella monomegacantha Kruse, 1959, P. indonesiensis Palm, 2004, Parachristianella sp., Pseudochristianella southwelli Campbell & Beveridge, 1990, Prochristianella macracantha Palm, 2004, Prochristianella spp. and Dollfusiella spp. from the host intestine. The most abundant trypanorhynchs were Dollfusiella that were found inseven different elasmobranch species. Pastinachus cf. sephen (Forsskål) was most species rich, with at least eight different trypanorhynch species. Highest prevalence (100%) was recorded for Pseudochristianella southwelli with a maximum intensity of 24 in Rhinobatos cf. punctifer Compagno & Randall (n=5). Within the elasmobranchs, highest prevalence (83.3%) was seen for Otobothrium carcharidis with a maximum intensity of 39 in Rhizoprionodon acutus (Rüppell). Host specificity values were recalculated for Kotorella pronosoma, Pseudogrillotia perelica, Callitetrarhynchus gracilis and Proemotobothrium southwelli.

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Mukhtar, Maryam, Niall Ashfield, Ludmila Vodickova, Veronika Vymetalkova, Miroslav Levy, Václav Liska, Jan Bruha, et al. "The Associations of Selenoprotein Genetic Variants with the Risks of Colorectal Adenoma and Colorectal Cancer: Case–Control Studies in Irish and Czech Populations." Nutrients 14, no. 13 (June 29, 2022): 2718. http://dx.doi.org/10.3390/nu14132718.

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Background: Selenium manifests its biological effects through its incorporation into selenoproteins, which play several roles in countering oxidative and inflammatory responses implicated in colorectal carcinogenesis. Selenoprotein genetic variants may contribute to colorectal cancer (CRC) development, as we previously observed for SNP variants in a large European prospective study and a Czech case–control cohort. Methods: We tested if significantly associated selenoprotein gene SNPs from these studies were also associated with CRC risk in case–control studies from Ireland (colorectal neoplasia, i.e., cancer and adenoma cases: 450, controls: 461) and the Czech Republic (CRC cases: 718, controls: 646). Genotyping of 23 SNPs (20 in the Irish and 13 in the Czechs) was performed by competitive specific allele-specific PCR (KASPar). Multivariable adjusted logistic regression was used to assess the associations with CRC development. Results: We found significant associations with an increased CRC risk for rs5859 (SELENOF) and rs2972994 (SELENOP) in the Irish cohort but only with rs4802034 (SELENOV) in the Czechs. Significant associations were observed for rs5859 (SELENOF), rs4659382 (SELENON), rs2972994 (SELENOP), rs34713741 (SELENOS), and the related Se metabolism gene variant rs2275129 (SEPHS1) with advanced colorectal neoplasia development. However, none of these findings retained significance after multiple testing corrections. Conclusions: Several SNPs previously associated with CRC risk were also associated with CRC or colorectal neoplasia development in either the Irish or Czech cohorts. Selenoprotein gene variation may modify CRC risk across diverse European populations, although the specific variants may differ.

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Salami, Olusola, and Oluuolc Osonuhi. "Growth and yield of maize and cassava cultivars as affected by mycorrhizal inoculation and alley cropping regime." Journal of Agricultural Sciences, Belgrade 51, no. 2 (2006): 123–32. http://dx.doi.org/10.2298/jas0602123s.

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Effect of myeorrhizal inoculation and two pruning regimes in experimental alley cropping treatments on the leaf biomass and nutrient yield of sole and mixed Gliricidica septum (a Modulating plant) ami Senna siamea (a non-nodulating plant) were investigated both in the greenhouse and in the field. The impact of the mixtures of these legumes as hedgerows on maize and one cultivar of cassava was also studied on the Held. Gliricidia sepiuni prunnings were found to have high nutrient yields, notably 358.4 kg ha-1 of N and 14.7 kg ha-1 of P as well as fast decomposition and nutrient release. In both Giricidia and Senna. there was similar leaf dry matter values in sole and mixed inoculated or non-inoculated trees for either of the pruning regime and for most of the pruning harvests, although significant differences occurred between inoculated and non-inoculated mixed or sole trees. There was no difference between the total leaf dry matter of the two- and three-month pruning regimes in G. sepium. However, in contrast to G. sepium, the total leaf dry matter of the two-month pruning regime of iS'. sianica was lower than its three-month pruning regime, except for sole non-inoculated trees. Generally, inoculation and mixing of trees in the same hedgerows significantly increased the total N and P yield in G. sepium and S. siantea with greater values in the former than the latter. In G. sephium and except for mixed inoculated trees, while total N yield in the leaf was higher in three-monthly primed than two-monthly pruned trees, the converse was the case for P. For S. siamea the total N and P yield were higher in three-monthly than two-monthly pruned trees. Myeorrhizal inoculations consistently increased the yield of the cassava root tuber and maize grain over their non-inoculated counterparts.

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DAVARYNEJAD, Gholamhossein, Mehdi ZAREI, and Peter Tamas NAGY. "Identification and Quantification of Heavy Metals Concentrations in Pistacia." Notulae Scientia Biologicae 5, no. 4 (November 30, 2013): 438–44. http://dx.doi.org/10.15835/nsb549115.

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The levels of heavy metals are very important in pistachio nuts, because the edible nuts have an important and increasing role in human nutrition. Pistachio is one of the native nuts of Iran which contains high genetic resources, but there is insufficient information regarding nutritional properties and other elements like heavy metals. The objective of the present study was to investigate and compare heavy metals contents in the kernels of various pistachio samples including; ‘Daneshmandi’, ‘Sephid’, ‘Garmeh’, ‘Momtaz’, ‘Ahmad Aghaei’, ‘Badami Zarand’, Pistacia atlantica Desf. (‘Baneh’), Pistacia vera ‘Sarakhs’ and chance seedling as ‘Non-grafted 1’, ‘Non-grafted 2’ and ‘Non-grafted 3’. Inductively coupled plasma emission spectrophotometer (ICP) was used for the determination of aluminium, chromium, nickel, copper, strontium, arsenic, cadmium and cobalt concentrations in pistachio kernels. This study showed that there were significant differences among the samples in all measured heavy metals except the arsenic, cadmium and cobalt. The content of aluminium varied from 3.22 to 9.59 (mg kg-1 of dry matter) and chromium concentration from 0.60 to 1.86 (mg kg-1 of dry matter). The nickel content of examined pistachio samples was found between 0.43 and 3.63 (mg kg-1 of dry matter) and copper ranged from 3.20 to 12.33 (mg kg-1 of dry matter). The strontium content was observed between 4.96 and 24.93 (mg kg-1 of dry matter). The contents of arsenic, cadmium and cobalt not reported, because their amounts were lower than the detection limit of the applied measuring method (ICP). These data demonstrated that the concentrations of heavy metals in pistachios varied by cultivar.

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48

Chisholm, L. A., and I. D. Whittington. "A revision ofDendromonocotyleHargis, 1955 (Monogenea: Monocotylidae) with a description of a new species fromPastinachus sephen(Forsskål) (Myliobatiformes: Dasyatididae) from the Great Barrier Reef, Australia." Journal of Natural History 29, no. 5 (October 1995): 1093–119. http://dx.doi.org/10.1080/00222939500770461.

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49

ROBERTS, TYSON R. "Francis Hamilton and the freshwater stingrays described in his Gangetic fishes (1822)." Archives of Natural History 25, no. 2 (June 1998): 267–79. http://dx.doi.org/10.3366/anh.1998.25.2.267.

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Direct evidence bearing on identification of the two new species of Gangetic stingrays named Raia fluviatilis and R. sancur by Hamilton, 1822 comprises 1) the first written account by Hamilton (then Buchanan) of his encounters with Gangetic stingrays in 1807–1813, written at the time in manuscript, but not published until 1877; 2) Hamilton's accounts of Raia fluviatilis and Raia sancur published in 1822; 3) Hamilton drawing IV 7 in the archives of the Asiatic Society of Bengal (never published, original now lost); and 4) Hamilton drawing IV 65 in the same archives (published by Hora, 1929, original now lost; this drawing is not a copy or a version of drawing IV 7). The description of R. sancur clearly is based on a species of the genus Pastinachus. Drawing IV 7 presumably is the unfinished drawing of R. sancur mentioned by Hamilton, 1822, and is therefore also of a Pastinachus. Drawing IV 65, not mentioned by Hamilton, a complete drawing with dorsal and ventral views of a newborn male Pastinachus with an intact sting, is identified as based on Raia fluviatilis. Pending revision of the genus Pastinachus, the Gangetic species is tentatively identified as P. sephen (Forsskål, 1775). Identification of Raia fluviatilis with a large freshwater species of Gangetic Himantura advocated by Annandale, 1910; Chaudhuri, 1912; Compagno and Cook, 1996; and Zorzi, 1996 is based on unwarranted assumptions. There is no definite evidence that Hamilton ever saw a Gangetic Himantura. Himantura chaophraya Monkolprasit and Roberts, 1990 is the only available name applicable to huge large tropical Asian freshwater stingrays of the dasyatid genus Himantura. No specimens of Gangetic Himantura exist in present museum collections.

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Mitchell, J. P., W. T. Lanini, S. R. Temple, E. V. Herrero, E. M. Miyao, P. Brostrom, R. Morse, and F. Thomas. "449 Conservation Tillage Row Crop Production in California." HortScience 34, no. 3 (June 1999): 522A—522. http://dx.doi.org/10.21273/hortsci.34.3.522a.

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Conservation tillage (CT) row crop production is currently not widely adopted in California. Recently, however, interest in evaluating the potential of CT systems to reduce production costs and improve soil quality is growing in many areas in the state. In 1997 and 1998, we evaluated four cover crop mulches (rye/vetch, triticale/vetch, Sava medic, and Sephi medic) in a CT-transplanted tomato system relative to the conventional winter fallow (CF) practice. In both years, yields were comparable to the CF under the triticale/vetch and rye/vetch mulches. Earthworm populations after 2 years of CT production were increased 2- to 5-fold under mulches relative to the CF system. Soil carbon was increased by 16% and 6% after 2 years of CT production under the triticale/vetch and rye/vetch mulches, respectively. Weed suppression under the triticale/vetch and rye/vetch was comparable to the CF with herbicide system early in the season in both years but was maintained through harvest in only one season. Soil water storage (0-90 cm) was similar at the beginning of the tomato season in triticale/vetch, rye/vetch, and fallow plots but was higher under the mulches during much of the last 45 days of the 1998 season. Further refinement of CT practices in California's vegetable production regions is needed before wider adoption is likely.

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