Статті в журналах з теми "S1P receptor antagonists"
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Sumida, Grant M., and W. Daniel Stamer. "S1P2 receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology." American Journal of Physiology-Cell Physiology 300, no. 5 (May 2011): C1164—C1171. http://dx.doi.org/10.1152/ajpcell.00437.2010.
Повний текст джерелаLukas, Susan, Lori Patnaude, Sokol Haxhinasto, Anthony Slavin, Melissa Hill-Drzewi, Josh Horan, and Louise Kelly Modis. "No Differences Observed among Multiple Clinical S1P1 Receptor Agonists (Functional Antagonists) in S1P1 Receptor Down-regulation and Degradation." Journal of Biomolecular Screening 19, no. 3 (September 3, 2013): 407–16. http://dx.doi.org/10.1177/1087057113502234.
Повний текст джерелаZhang, Dong Dong, Bona Linke, Jing Suo, Aleksandra Zivkovic, Yannick Schreiber, Nerea Ferreirós, Marina Henke, Gerd Geisslinger, Holger Stark, and Klaus Scholich. "Antinociceptive effects of FTY720 during trauma-induced neuropathic pain are mediated by spinal S1P receptors." Biological Chemistry 396, no. 6-7 (June 1, 2015): 783–94. http://dx.doi.org/10.1515/hsz-2014-0276.
Повний текст джерелаHafizi, Redona, Faik Imeri, Roland H. Wenger та Andrea Huwiler. "S1P Stimulates Erythropoietin Production in Mouse Renal Interstitial Fibroblasts by S1P1 and S1P3 Receptor Activation and HIF-2α Stabilization". International Journal of Molecular Sciences 22, № 17 (31 серпня 2021): 9467. http://dx.doi.org/10.3390/ijms22179467.
Повний текст джерелаWerth, Stephan, Helge Müller-Fielitz, and Walter Raasch. "Obesity-stimulated aldosterone release is not related to an S1P-dependent mechanism." Journal of Endocrinology 235, no. 3 (December 2017): 251–65. http://dx.doi.org/10.1530/joe-16-0550.
Повний текст джерелаZhang, Gengqian, Sulei Xu, Yan Qian, and Pingnian He. "Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules." American Journal of Physiology-Heart and Circulatory Physiology 299, no. 5 (November 2010): H1494—H1504. http://dx.doi.org/10.1152/ajpheart.00462.2010.
Повний текст джерелаCorvino, Angela, Ida Cerqua, Alessandra Lo Bianco, Giuseppe Caliendo, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, et al. "Antagonizing S1P3 Receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis." International Journal of Molecular Sciences 22, no. 16 (August 17, 2021): 8861. http://dx.doi.org/10.3390/ijms22168861.
Повний текст джерелаToebbe, JT, and Mary Beth Genter. "An Update on Sphingosine-1-Phosphate and Lysophosphatidic Acid Receptor Transcripts in Rodent Olfactory Mucosa." International Journal of Molecular Sciences 23, no. 8 (April 14, 2022): 4343. http://dx.doi.org/10.3390/ijms23084343.
Повний текст джерелаGodessart, Nuria, Sanam Mustafa, Vlad Dolgachev, Mariona Aulí, Núria Aguilar, Judit Cabedo, Marta Calbet, et al. "The S1P1 receptor antagonist W146 induces lymphopenia in mice. Demonstration that functional antagonism of S1P1 is the mechanism of lymphopenia evoked by fingolimod-like compounds. (140.15)." Journal of Immunology 184, no. 1_Supplement (April 1, 2010): 140.15. http://dx.doi.org/10.4049/jimmunol.184.supp.140.15.
Повний текст джерелаJuarez, Julius G., Nadia Harun, Marilyn Thien, Robert Welschinger, Rana Baraz, Aileen Dela Pena, Stuart M. Pitson, et al. "Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice." Blood 119, no. 3 (January 19, 2012): 707–16. http://dx.doi.org/10.1182/blood-2011-04-348904.
Повний текст джерелаSeitz, Gabriele, Sedat Yildirim, Andreas M. Boehmler, Lothar Kanz, and Robert Möhle. "Sphingosine 1-Phosphate (S1P) Induces Migration and ERK/MAP-Kinase-Dependent Proliferation in Chronic Lymphocytic Leukemia (B-CLL) Due to Expression of the G Protein-Coupled Receptors S1P1/4." Blood 106, no. 11 (November 16, 2005): 4996. http://dx.doi.org/10.1182/blood.v106.11.4996.4996.
Повний текст джерелаKitada, Yoshihiko, Kazuo Kajita, Koichiro Taguchi, Ichiro Mori, Masahiro Yamauchi, Takahide Ikeda, Mikako Kawashima, et al. "Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice." Endocrinology 157, no. 5 (March 4, 2016): 1839–51. http://dx.doi.org/10.1210/en.2015-1768.
Повний текст джерелаGandy, K. Alexa Orr, Daniel Canals, Mohamad Adada, Masayuki Wada, Patrick Roddy, Ashley J. Snider, Yusuf A. Hannun, and Lina M. Obeid. "Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins." Biochemical Journal 449, no. 3 (January 9, 2013): 661–72. http://dx.doi.org/10.1042/bj20120213.
Повний текст джерелаZhu, Qing, Min Xia, Zhengchao Wang, Pin-Lan Li, and Ningjun Li. "A novel lipid natriuretic factor in the renal medulla: sphingosine-1-phosphate." American Journal of Physiology-Renal Physiology 301, no. 1 (July 2011): F35—F41. http://dx.doi.org/10.1152/ajprenal.00014.2011.
Повний текст джерелаChumanevich, Alena, Piper Wedman, and Carole A. Oskeritzian. "Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2." Mediators of Inflammation 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/1503206.
Повний текст джерелаBalthasar, Sonja, Johanna Samulin, Hanna Ahlgren, Nina Bergelin, Mathias Lundqvist, Emil C. Toescu, Margaret C. Eggo, and Kid Törnquist. "Sphingosine 1-phosphate receptor expression profile and regulation of migration in human thyroid cancer cells." Biochemical Journal 398, no. 3 (August 29, 2006): 547–56. http://dx.doi.org/10.1042/bj20060299.
Повний текст джерелаNiedernberg, Anke, Sorin Tunaru, Andree Blaukat, Bruce Harris, and Evi Kostenis. "Comparative Analysis of Functional Assays for Characterization of Agonist Ligands at G Protein-Coupled Receptors." Journal of Biomolecular Screening 8, no. 5 (October 2003): 500–510. http://dx.doi.org/10.1177/1087057103257555.
Повний текст джерелаStandoli, Sara, Sara Pecchioli, Daniel Tortolani, Camilla Di Meo, Federico Fanti, Manuel Sergi, Marina Bacci, et al. "The TRPV1 Receptor Is Up-Regulated by Sphingosine 1-Phosphate and Is Implicated in the Anandamide-Dependent Regulation of Mitochondrial Activity in C2C12 Myoblasts." International Journal of Molecular Sciences 23, no. 19 (September 21, 2022): 11103. http://dx.doi.org/10.3390/ijms231911103.
Повний текст джерелаDel Gaudio, Ilaria, Sebastian Hendrix, Christina Christoffersen, and Christian Wadsack. "Neonatal HDL Counteracts Placental Vascular Inflammation via S1P–S1PR1 Axis." International Journal of Molecular Sciences 21, no. 3 (January 25, 2020): 789. http://dx.doi.org/10.3390/ijms21030789.
Повний текст джерелаChen, Zhoumou, Timothy M. Doyle, Livio Luongo, Tally M. Largent-Milnes, Luigino Antonio Giancotti, Grant Kolar, Silvia Squillace, et al. "Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain." Proceedings of the National Academy of Sciences 116, no. 21 (May 8, 2019): 10557–62. http://dx.doi.org/10.1073/pnas.1820466116.
Повний текст джерелаTao, Rong, Holly E. Hoover, Norman Honbo, Mikaila Kalinowski, Conrad C. Alano, Joel S. Karliner, and Robert Raffai. "High-density lipoprotein determines adult mouse cardiomyocyte fate after hypoxia-reoxygenation through lipoprotein-associated sphingosine 1-phosphate." American Journal of Physiology-Heart and Circulatory Physiology 298, no. 3 (March 2010): H1022—H1028. http://dx.doi.org/10.1152/ajpheart.00902.2009.
Повний текст джерелаLatif, Ahmed Abdel, Anush K. Karapetyan, Yuri Klyachkin, Manjula Sunkara, Susan Smyth, Mariusz Z. Ratajczak, and Andrew J. Morris. "Novel Role for Bioactive Lipids in Mobilization of Bone Marrow Stem Cells During Myocardial Ischemia: Sphingosine-1 Phosphate (S1P) As Potential Therapeutic Target." Blood 120, no. 21 (November 16, 2012): 1911. http://dx.doi.org/10.1182/blood.v120.21.1911.1911.
Повний текст джерелаSchira-Heinen, Jessica, Luzhou Wang, Seda Akgün, Sofia Blum, Brigida Ziegler, André Heinen, Hans-Peter Hartung, and Patrick Küry. "Modulation of Specific Sphingosine-1-Phosphate Receptors Augments a Repair Mediating Schwann Cell Phenotype." International Journal of Molecular Sciences 23, no. 18 (September 7, 2022): 10311. http://dx.doi.org/10.3390/ijms231810311.
Повний текст джерелаStockstill, Katherine, Timothy M. Doyle, Xisheng Yan, Zhoumou Chen, Kali Janes, Joshua W. Little, Kathryn Braden, et al. "Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain." Journal of Experimental Medicine 215, no. 5 (April 27, 2018): 1301–13. http://dx.doi.org/10.1084/jem.20170584.
Повний текст джерелаLandeen, Lee K., Dorothy A. Dederko, Colleen S. Kondo, Betty S. Hu, Nakon Aroonsakool, Jason H. Haga, and Wayne R. Giles. "Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 2 (February 2008): H736—H749. http://dx.doi.org/10.1152/ajpheart.00316.2007.
Повний текст джерелаStepanovska Tanturovska, Bisera, Aleksandra Zivkovic, Faik Imeri, Thomas Homann, Burkhard Kleuser, Holger Stark, and Andrea Huwiler. "ST-2191, an Anellated Bismorpholino Derivative of Oxy-Fingolimod, Shows Selective S1P1 Agonist and Functional Antagonist Potency In Vitro and In Vivo." Molecules 26, no. 17 (August 24, 2021): 5134. http://dx.doi.org/10.3390/molecules26175134.
Повний текст джерелаHla, Timothy, Sylvain Galvani, Shahin Rafii, and Ralph Nachman. "S1P and the birth of platelets." Journal of Experimental Medicine 209, no. 12 (November 19, 2012): 2137–40. http://dx.doi.org/10.1084/jem.20122284.
Повний текст джерелаMaceyka, Michael, Sergio E. Alvarez, Sheldon Milstien, and Sarah Spiegel. "Filamin A Links Sphingosine Kinase 1 and Sphingosine-1-Phosphate Receptor 1 at Lamellipodia To Orchestrate Cell Migration." Molecular and Cellular Biology 28, no. 18 (July 21, 2008): 5687–97. http://dx.doi.org/10.1128/mcb.00465-08.
Повний текст джерелаLuo, Dongdong, Zhikun Guo, Xuecui Zhao, Lijuan Wu, Xiaochun Liu, Yingzhi Zhang, Yuhang Zhang, et al. "Novel 5-fluorouracil sensitizers for colorectal cancer therapy: Design and synthesis of S1P receptor 2 (S1PR2) antagonists." European Journal of Medicinal Chemistry 227 (January 2022): 113923. http://dx.doi.org/10.1016/j.ejmech.2021.113923.
Повний текст джерелаLee, Chi-Ho, and Ji Woong Choi. "S1P/S1P2 Signaling Axis Regulates Both NLRP3 Upregulation and NLRP3 Inflammasome Activation in Macrophages Primed with Lipopolysaccharide." Antioxidants 10, no. 11 (October 27, 2021): 1706. http://dx.doi.org/10.3390/antiox10111706.
Повний текст джерелаLee, Jen-Fu, Sharon Gordon, Rosendo Estrada, Lichun Wang, Deanna L. Siow, Binks W. Wattenberg, David Lominadze, and Menq-Jer Lee. "Balance of S1P1and S1P2signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature." American Journal of Physiology-Heart and Circulatory Physiology 296, no. 1 (January 2009): H33—H42. http://dx.doi.org/10.1152/ajpheart.00097.2008.
Повний текст джерелаYoon, Chang Min, Bok Sil Hong, Hyung Geun Moon, Seyoung Lim, Pann-Ghill Suh, Yoon-Keun Kim, Chi-Bom Chae, and Yong Song Gho. "Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways." Blood 112, no. 4 (August 15, 2008): 1129–38. http://dx.doi.org/10.1182/blood-2007-11-125203.
Повний текст джерелаZhang, Yujin, Shushan Zhao, Hongyu Wu, Xia Hu, Renna Luo, Nicholas Parchim, Rodney E. Kellems, and Yang Xia. "Sphingosine 1-Phosphate (S1P)/S1P Receptor 1 Pathway Has an Essential Role for Sickle Cell Disease." Blood 124, no. 21 (December 6, 2014): 4063. http://dx.doi.org/10.1182/blood.v124.21.4063.4063.
Повний текст джерелаKoch, Alexander, Manuel Jäger, Anja Völzke, Georgios Grammatikos, Dagmar Meyer zu Heringdorf, Andrea Huwiler, and Josef Pfeilschifter. "Downregulation of sphingosine 1-phosphate (S1P) receptor 1 by dexamethasone inhibits S1P-induced mesangial cell migration." Biological Chemistry 396, no. 6-7 (June 1, 2015): 803–12. http://dx.doi.org/10.1515/hsz-2014-0288.
Повний текст джерелаEl-Shewy, Hesham M., Mimi Sohn, Parker Wilson, Mi Hye Lee, Samar M. Hammad, Louis M. Luttrell, and Ayad A. Jaffa. "Low-Density Lipoprotein Induced Expression of Connective Tissue Growth Factor via Transactivation of Sphingosine 1-Phosphate Receptors in Mesangial Cells." Molecular Endocrinology 26, no. 5 (May 1, 2012): 833–45. http://dx.doi.org/10.1210/me.2011-1261.
Повний текст джерелаDamirin, Alatangaole, Hideaki Tomura, Mayumi Komachi, Jin-Peng Liu, Chihiro Mogi, Masayuki Tobo, Ju-Qiang Wang, et al. "Role of lipoprotein-associated lysophospholipids in migratory activity of coronary artery smooth muscle cells." American Journal of Physiology-Heart and Circulatory Physiology 292, no. 5 (May 2007): H2513—H2522. http://dx.doi.org/10.1152/ajpheart.00865.2006.
Повний текст джерела&NA;. "INTERNALIZATION OF THE S1P-1 RECEPTOR IS MEDIATED BY AGONISTS AND NOT BY ANTAGONISTS BUT DOES NOT REQUIRE INTRACELLULAR SIGNALING." Transplantation 82, Suppl 2 (July 2006): 426–27. http://dx.doi.org/10.1097/00007890-200607152-01067.
Повний текст джерелаPelz, Andreas, Hanne Schaffert, Radharani Diallo, Falk Hiepe, Andreas Meisel, and Siegfried Kohler. "S1P receptor antagonists fingolimod and siponimod do not improve the outcome of experimental autoimmune myasthenia gravis mice after disease onset." European Journal of Immunology 48, no. 3 (December 19, 2017): 498–508. http://dx.doi.org/10.1002/eji.201747187.
Повний текст джерелаGerminario, Elena, Samantha Peron, Luana Toniolo, Romeo Betto, Francesca Cencetti, Chiara Donati, Paola Bruni, and Daniela Danieli-Betto. "S1P2 receptor promotes mouse skeletal muscle regeneration." Journal of Applied Physiology 113, no. 5 (September 1, 2012): 707–13. http://dx.doi.org/10.1152/japplphysiol.00300.2012.
Повний текст джерелаIgawa, Satomi, Jae Eun Choi, Zhenping Wang, Yu-Ling Chang, Chia-Chi Wu, Tyler Werbel, Akemi Ishida-Yamamoto, and Anna Di Nardo. "Sphingosine 1-phosphate is a harbinger of S. aureus invasion and activates host defense in epithelial barriers." Journal of Immunology 202, no. 1_Supplement (May 1, 2019): 126.30. http://dx.doi.org/10.4049/jimmunol.202.supp.126.30.
Повний текст джерелаCohan, Stanley, Elisabeth Lucassen, Kyle Smoot, Justine Brink, and Chiayi Chen. "Sphingosine-1-Phosphate: Its Pharmacological Regulation and the Treatment of Multiple Sclerosis: A Review Article." Biomedicines 8, no. 7 (July 18, 2020): 227. http://dx.doi.org/10.3390/biomedicines8070227.
Повний текст джерелаWhetzel, Angela M., David T. Bolick, and Catherine C. Hedrick. "Sphingosine-1-phosphate inhibits high glucose-mediated ERK1/2 action in endothelium through induction of MAP kinase phosphatase-3." American Journal of Physiology-Cell Physiology 296, no. 2 (February 2009): C339—C345. http://dx.doi.org/10.1152/ajpcell.00293.2008.
Повний текст джерелаSchwalm, Stephanie, Tankica Maneva Timcheva, Iuliia Filipenko, Mahsa Ebadi, Lotte P. Hofmann, Uwe Zangemeister-Wittke, Josef Pfeilschifter, and Andrea Huwiler. "Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts." Biological Chemistry 396, no. 6-7 (June 1, 2015): 813–25. http://dx.doi.org/10.1515/hsz-2014-0289.
Повний текст джерелаKalhori, Veronica, Melissa Magnusson, Muhammad Yasir Asghar, Ilari Pulli, and Kid Törnquist. "FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion." Endocrine-Related Cancer 23, no. 5 (May 2016): 457–68. http://dx.doi.org/10.1530/erc-16-0050.
Повний текст джерелаPergolizzi, Jr., Joseph V., and Jo Ann LeQuang. "Sigma Antagonists for Treatment of Neuropathic Pain Syndromes in Cancer Patients: A Narrative Review." Journal of Cancer Research Updates 11 (October 27, 2022): 70–77. http://dx.doi.org/10.30683/1929-2279.2022.11.10.
Повний текст джерелаCurry, F. E., J. F. Clark, and R. H. Adamson. "Erythrocyte-derived sphingosine-1-phosphate stabilizes basal hydraulic conductivity and solute permeability in rat microvessels." American Journal of Physiology-Heart and Circulatory Physiology 303, no. 7 (October 1, 2012): H825—H834. http://dx.doi.org/10.1152/ajpheart.00181.2012.
Повний текст джерелаOskeritzian, Carole A., Megan M. Price, Nitai C. Hait, Dmitri Kapitonov, Yves T. Falanga, Johanna K. Morales, John J. Ryan, Sheldon Milstien, and Sarah Spiegel. "Essential roles of sphingosine-1–phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema." Journal of Experimental Medicine 207, no. 3 (March 1, 2010): 465–74. http://dx.doi.org/10.1084/jem.20091513.
Повний текст джерелаdela Paz, Nathaniel G., Benoît Melchior та John A. Frangos. "Shear stress induces Gαq/11 activation independently of G protein-coupled receptor activation in endothelial cells". American Journal of Physiology-Cell Physiology 312, № 4 (1 квітня 2017): C428—C437. http://dx.doi.org/10.1152/ajpcell.00148.2016.
Повний текст джерелаBandhuvula, Padmavathi, Norman Honbo, Guan-Ying Wang, Zhu-Qiu Jin, Henrik Fyrst, Meng Zhang, Alexander D. Borowsky, Lisa Dillard, Joel S. Karliner, and Julie D. Saba. "S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart." American Journal of Physiology-Heart and Circulatory Physiology 300, no. 5 (May 2011): H1753—H1761. http://dx.doi.org/10.1152/ajpheart.00946.2010.
Повний текст джерелаShah, Mithun Vinod, Ranran Zhang, Rosalyn Irby, Ravi Kothapalli, Xin Liu, Ty Arrington, Bryan Frank, Norman H. Lee, and Thomas P. Loughran. "Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes." Blood 112, no. 3 (August 1, 2008): 770–81. http://dx.doi.org/10.1182/blood-2007-11-121871.
Повний текст джерела