Дисертації з теми "Regulatory DC"
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COMI, MICHELA. "Unravelling the fingerprint and regulatory functions of human tolerogenic DC-10." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2016. http://hdl.handle.net/10281/137397.
Повний текст джерелаTeaster, Neal D. Chapman Kent Dean. "A regulatory role for N-acylethanolamine metabolism in Arabidopsis thaliana seeds and seedlings." [Denton, Tex.] : University of North Texas, 2009. http://digital.library.unt.edu/permalink/meta-dc-10978.
Повний текст джерелаZeRuth, Gary T. "Isolation and Functional Characterization of a Dioxin-Inducible CYP1A Regulatory Region From Zebrafish (Danio rerio)." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002447.
Повний текст джерелаRuzek, Mitch James. "Evolution of a conserved gene regulatory network among echinoderms : a comparison of genes expressed in the skeletogenetic lineage of the ophuroid Ophiocoma wendtii and the echinoid Strongylocentrotus purpuratus." [Tampa, Fla] : University of South Florida, 2009. http://purl.fcla.edu/usf/dc/et/SFE0003181.
Повний текст джерелаJackson, Erin M. "Integrating Leader-Member Exchange and Organizational Justice: Why Justice Depends on Relationship Quality." [Tampa, Fla] : University of South Florida, 2008. http://purl.fcla.edu/usf/dc/et/SFE0002366.
Повний текст джерелаBlumenthal, Pamela M. "Local Land Use Regulatory Regimes and Residential Development Outcomes| An Analysis of Subdivision Review in Four Counties in the DC Region." Thesis, The George Washington University, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=3598490.
Повний текст джерелаLand use regulations affect housing prices, with more restrictive regulatory environments associated with higher prices. Yet, regulations are only a part of the regulatory regime in which land use decisions are made, leading to the question: how do land use regulatory regimes affect housing prices? This study examines and compares the land use regulatory regimes of four counties, Frederick, MD, Montgomery, MD, Fairfax, VA, and Loudoun, VA through interviews, project files, and regulatory review to learn how the combination of structures, rules, norms, principles, and expectations, relate to housing prices. State differences in the tools available lead to Virginia counties having a more predictable, but not faster, subdivision review process than Maryland counties. More importantly, local differences in developer contributions for mitigating the impact of development, community involvement, and perspectives on development affect the cost and predictability of the residential development review process. These jurisdictional differences support the need to focus research on regulatory regimes rather than simply regulations to identify changes to reduce unnecessary costs that increase house prices.
Karnam, Anupama. "Role of Wnt/β-catenin pathway in the anti-inflammatory mechanism of therapeutic normal immunoglobulins Wuchereria bancrofti filaria activates human dendritic cells and polarizes T helper 1 and regulatory T cells via toll-like receptor 4 Regulatory T cells induce activation rather than suppression of human basophils". Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS642.
Повний текст джерелаIntravenous immunoglobulin (IVIG) is a therapeutic preparation of pooled normal IgG obtained from the several thousand healthy donors. It is established as first-line therapy for many autoimmune and inflammatory diseases. In the first part of my thesis, I have investigated if IVIG therapy interferes with the serological detection of Zika virus infection in Guillain–Barré syndrome (GBS) patients. By analyzing the plasma of GBS patients treated with IVIG for anti-Zika IgG, I have demonstrated that IVIG therapy in GBS patients does not interfere with the serological Zika detection. The second part addresses the immunoregulatory role of IVIG on human basophil function. Unlike in mice, IVIG does not require DC-SIGN-dependent IL-33 for the activation of human basophils. IVIG directly induces the activation of IL-3-primed human basophils and secretion of IL-4, IL-6, and IL-8 by directly interacting with the basophil surface-bound IgE. This function was F(ab’)2-dependent and involves Syk activation. These results demonstrate a novel mechanism of human basophil activation by IVIG. The last part unravels the signaling pathways associated with IVIG-mediated anti-inflammatory effects specifically the Wnt/β-catenin pathway, which imparts tolerogenic properties to dendritic cells (DCs) and protection against experimental autoimmune encephalomyelitis (EAE). My data shows that IVIG activates β-catenin in human DC along with upregulation of Wnt 5a. Activation of β-catenin requires intact IgG and LRP5/6 co-receptors. However, despite the activation of β-catenin by IVIG, this pathway is dispensable for its anti-inflammatory actions both in vitro and in vivo in the EAE model
Nghe, Brandon K. "Cascaded Linear Regulator with Positive Voltage Tracking Switching Regulator." DigitalCommons@CalPoly, 2020. https://digitalcommons.calpoly.edu/theses/2173.
Повний текст джерелаGe, Ting. "Resonant Cross-Commutated Dc-Dc Regulators with Omni-Coupled Inductors." Diss., Virginia Tech, 2018. http://hdl.handle.net/10919/84936.
Повний текст джерелаPh. D.
Bevrani, Hassan. "Modeling, Nonlinear and Robust control of DC-DC Switching Regulators." Thesis, K. N. Toosi University of Technology, 1997.
Знайти повний текст джерелаNisar, Kashif. "DC to DC converter for smart dust." Thesis, Linköpings universitet, Institutionen för systemteknik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-77247.
Повний текст джерелаChiaruttini, Giulia. "Identification of vesicular SNARE proteins involved in the secretoryintracellular trafficking of IL-12 in dendritic cells." Doctoral thesis, Università degli studi di Trieste, 2013. http://hdl.handle.net/10077/8636.
Повний текст джерелаDendritic cells (DCs) are professional antigen presenting cells. They have the unique ability of recognizing antigens, internalizing and processing them for presentation on MHC complexes. DCs also express pattern-recognition receptors like Toll-like receptors (TLRs), which recognize pathogen-associated molecular patterns and induce DCs maturation. As a consequence DCs increase their antigens presenting ability, their levels of co-stimulatory molecules on the cell surface, and their production of cytokines, which are critical for inducing specific T cell activation. All these functions make DCs key elements in the immunological response against pathogens, viruses and tumors. One of the most important cytokines in T cell priming, interleukine-12 (IL-12), begins to be largely transcribed immediately after TLR activation. We have previously shown that in DCs engaged in antigen specific immunological synapses (IS), IL-12 is found enriched in the proximity of the contact site between DC and T cells, and several evidences suggest that its secretion is polarized towards the T cell. These data indicate that polarized trafficking of cytokines containing vesicles in DCs is a mechanism to optimize T cell priming. Polarized trafficking of soluble mediators through defined subcellular areas has been described as fundamental for the function of several other immune cells, but at present a clear characterization of the pathways and organelles implicated in the regulation of cytokine secretion in dendritic cells is still missing. The family of SNARE (soluble-N ethylmaleimide sensitive-factor accessory-protein (SNAP) receptor) proteins, which regulate the membrane fusion process during the intracellular trafficking of soluble mediators, has emerged as the most informative for the identification of such pathways. Indeed different SNAREs regulate diverse mechanisms such as the constitutive secretion of immune mediators, phagocytosis and endocytosis, or also the release of inflammatory mediators and products from secretory granules. During my thesis I have investigated the role of SNAREs in IL-12 secretion by DCs. I have analyzed the expression and modulation during maturation of three SNAREs, Syntaxin6, VAMP3 and VAMP7, that were previously shown to play a role in other immune cells. The subcellular localization and co-localization with the IL-12 subunits were analyzed in DCs alone and in the context of IS by immunofluorescence. I performed functional analyses by silencing SNAREs with the siRNA strategy to detect impairment in DC cytokines secretion and in T cell priming. These studies led to the identification of the lysosomal-late endosomal VAMP7 as a specific regulator in the polarized secretion of IL-12 during T cell priming. This suggest a role, in the secretion of soluble newly synthesized mediators, of late endosomal organelles, until now thought to be implicated only in the regulated secretion of pre-constituted mediators such as cytotoxic granules. Furthermore VAMP3 was found to downregulate the production of all the cytokines tested; we propose this SNARE as regulator of the TLR9 signaling pathway. The second part of the work stems from the concept that DCs properties become suppressed by the tumor microenvironment and many evidences suggest that tolerogenic DCs may be a crucial element in the development of tumor-mediated immune anergy. Different steps in the antigen presentation process are impaired, but also the pattern of secreted cytokines is skewed. In particular, how secretion of inflammatory cytokines becomes impaired in tumor-exposed DCs has not been investigated. I set up a model of mice bearing Lewis lung carcinoma (3LL) to analyze DCs in vitro (co-colture) and in vivo (spleen and tumor-bearing lungs). In all the models I observed a strong impairment in IL-12 production, upon restimulation with TLR agonists. In spleen DCs subtypes remained unchanged during tumor progression, whereas in tumor-bearing lungs the DC composition varied, with an expansion of CD11bhi DCs and a reduction in CD103+ DCs. DCs were isolated from all the three models to analyze the expression of trafficking proteins, and I found that tumor-exposed DCs downregulate all the SNAREs and in particular VAMP3. Moreover Rab27a, a GTPase implicated in the regulation of the exocytosis of secretory granules and lysosome-related organelles is also downregulated at protein level. These preliminary observations suggest that regulation of trafficking proteins in DCs may represent a novel pathway targeted during immunosuppression.
Le cellule dendritiche (DC) sono una importante classe di cellule presentanti l'antigene. Hanno l'esclusiva abilità di riconoscere gli antigeni, internalizzarli e processarli per la loro presentazione con il complesso maggiore di istocompatibilità. Le DC esprimono anche recettori "riconoscitori di pattern" come i recettori Toll-like (TLR), che riconoscono pattern molecolari associati ai patogeni e inducono la maturazione delle DC. Come conseguenza le DC aumentano la loro capacità di presentare gli antigeni, i loro livelli di molecole costimolatorie sulla superficie cellulare, e la loro produzione di citochine, che sono fondamentali per indurre l'attivazione specifica delle cellule T. Tutte queste funzioni rendono le DC elementi chiave nella risposta immunologica contro i patogeni, i virus e i tumori. Una delle più importanti citochine per l'induzione delle cellule T, l'interleuchina 12 (IL-12), inizia ad essere estensivamente trascritta immediatamente dopo l'attivatione dei TLR. Il nostro gruppo ha precedentemente mostrato che nelle DC impegnate in sinapsi immunologiche-antigene specifiche (IS), l'IL-12 si trova arricchita in prossimità del sito di contatto tra la DC e le cellule T, e varie evidenze suggeriscono che la sua secrezione è polarizzata verso la cellula T. Questi dati indicano che il traffico polarizzato di vescicole contenenti citochine nelle DC è un meccanismo per ottimizzare l'induzione delle cellule T. Il traffico polarizzato di mediatori solubili attraverso definite aree intracellulari è stato descritto come fondamentale per la funzione di varie cellule immunitarie, ma attualmente una chiara caratterizzazione delle vie di secrezione delle citochine nelle cellule dendritiche è ancora mancante. La famiglia delle proteine SNARE (soluble-N ethylmaleimide sensitive-factor accessory-protein (SNAP) receptor), che regolano il processo di fusione tra le membrane durante il traffico intracellulare di mediatori solubili, è emersa come la più informativa nell'identificazione di questo tipo di vie. Infatti diverse SNARE regolano diversi meccanismi, come la secrezione costitutiva di mediatori immunologici, la fagocitosi e l'endocitosi, o anche il rilascio di mediatori infiammatori e di prodotti sui granoli secretori. Durante la mia tesi ho investigato il ruolo delle SNARE nella secrezione dell'IL-12 nelle DC. Ho analizzato l'espressione e la modulazione durante la maturazione delle SNARE syntaxin6, VAMP3 e VAMP7, precedentemente descritte in altre cellule immunitarie. La localizzazione subcellulare e la colocalizzazione con le subunità dell'IL-12 sono state analizzate nelle DC da sole e nel contesto dell'IS attraverso l'immunofluorescenza. Ho svolto studi funzionali silenziando le SNARE con la strategia dei siRNA, per osservare diminuzioni nella secrezione delle citochine nelle DC. Questi studi hanno portato all'identificazione della lisosomale VAMP7 come regolatore specifico nella secrezione polarizzata dell'IL-12 durante l'induzione delle cellule T. Questo suggerisce un ruolo nella secrezione di mediatori solubili neosintetizzati, degli organelli endosomiali tardivi , finora ritenuti implicati solo nella secrezione regolata di mediatori pre-costituiti come i granuli citotossici. Inoltre si è visto che VAMP3 deregola la produzione di tutte le cotochine testate; proponiamo che questa SNARE sia un regolatore della via di segnalazione del TLR9. La seconda parte del lavoro parte dal concetto che le proprietà delle DC sono soppresse dal microambiente tumorale e molte evidenze suggeriscono che le DC tollerogeniche sarebbero un elemento fondamentale nello sviluppo dello spegnimento immunologico mediato dal tumore. Diversi punti nel processo di presentazione dell'antigene sono deregolate, ma anche il pattern di citochine secrete è modificato. In particolare, come la secrezione di citochine infiammatorie diventi deregolata nelle DC esposte al tumore non è stato investigato. Ho messo a punto un modello di topi con carcinoma polmonare di Lewis (3LL) per analizzare le DC in vitro (con co-colture) e in vivo (nella milza e nel polmone). In tutti i modelli ho osservato una forte diminuzione nella produzione dell'IL-12, dopo stimolazione con agonisti del TLR. Nella milza i sottotipi di DC sono rimasti simili durante la progressione tumorale, mentre nei polmoni affetti da tumore la composizione delle DC è variata, con un'espansione delle DC CD11b e una riduzione delle DC CD103. Le DC sono state isolate da tutti e tre i modelli per analizzare l'espressione delle proteine di traffico e ho osservato che le DC esposte al tumore deregolano tutte le SNARE e in particolare VAMP3. Inoltre anche Rab27a, una GTPasi implicata nella regolazione dell'esocitosi dei granuli secretori e degli organelli lisosomiali è trovata de-regolata a livello della proteina. Queste osservazioni preliminari suggeriscono che la regolazione delle proteine di traffico nelle DC potrebbe rappresentare una nuova via bersagliata durante lo sviluppo tumorale.
XXV Ciclo
1985
Raley, Jack. "Efficient DC-DC switch regulator applied iterative learning and anti-windup control /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p1457288.
Повний текст джерелаTitle from first page of PDF file (viewed November 14, 2008). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 65-66).
Ying, Tianrui. "Area efficient charge pumps and post low dropout regulators /." View Abstract or Full-Text, 2002. http://library.ust.hk/cgi/db/thesis.pl?ELEC%202002%20YING.
Повний текст джерелаWan, Kai. "Advanced current-mode control techniques for DC-DC power electronic converters." Diss., Rolla, Mo. : Missouri University of Science and Technology, 2009. http://scholarsmine.mst.edu/thesis/pdf/Wan_09007dcc80642d38.pdf.
Повний текст джерелаVita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed May 4, 2009) Includes bibliographical references.
Lei, Ernest. "Cascaded Linear Regulator with Negative Voltage Tracking Switching Regulator." DigitalCommons@CalPoly, 2020. https://digitalcommons.calpoly.edu/theses/2176.
Повний текст джерелаGummi, Karteek. "Derivation of new double-input DC-DC converters using the building block methodology." Diss., Rolla, Mo. : Missouri University of Science and Technology, 2008. http://scholarsmine.mst.edu/thesis/pdf/Gummi_09007dcc804fa7b9.pdf.
Повний текст джерелаVita. The entire thesis text is included in file. Title from title screen of thesis/dissertation PDF file (viewed May 12, 2008) Includes bibliographical references (p. 102-107).
Hunter, Daniel Scott. "Variable-frequency pulse-width-modulation for zero-voltage switching in a boost DC-DC regulator." Thesis, Monterey, California. Naval Postgraduate School, 1990. http://hdl.handle.net/10945/37543.
Повний текст джерелаA technique for operating a pulse-width-modulated (PWM) dc-dc regulator in the boost mode while switching the MOSFET when the drain-to-source potential is near zero volts was developed and is described in this thesis. This is accomplished by using frequency-modulation in addition to pulse-width-modulation. Zero-voltage switching will provide power converter designers an alternative for designing high-frequency converters with minimal transient turn-on losses, the predominant form of converter losses experienced in high frequency operation. High frequency operation will result in smaller reactive components, which produce higher power density converters, as well as increasing the transient response of the regulated converter. In addition to allowing for high frequency operation, the design exhibits many desirable power switch properties, such as limiting the peak voltage to the output voltage level and operating with the minimum possible current levels for a given power requirement. A circuit built and tested utilizing zero-voltage switching in a regulated boost converter verified the principles of operation for yielding a high-efficiency, high-frequency converter.
Åberg, Emil. "Optimering av styrsystem för DC-servo." Thesis, Uppsala universitet, Signaler och System, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-346489.
Повний текст джерелаManh, Vir Varinder. "An Integrated High Efficiency DC-DC Converter in 65 nm CMOS." Thesis, Linköpings universitet, Elektroniksystem, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-61237.
Повний текст джерелаAbdelfattah, Moataz. "Switched-Capacitor DC-DC Converters for Near-Threshold Design." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1500631539574741.
Повний текст джерелаAy, Gokce Mehmet. ""." Master's thesis, METU, 2004. http://etd.lib.metu.edu.tr/upload/12605283/index.pdf.
Повний текст джерелаknow-how&rdquo
required for building high performance (and high power) DC motor drives is gained in this research.
Shao, Hui. "System design and power management for ultra low energy applications using energy harvesting techniques /." View abstract or full-text, 2009. http://library.ust.hk/cgi/db/thesis.pl?ECED%202009%20SHAO.
Повний текст джерелаForghani-zadeh, Hassan Pooya. "An Integrated, Lossless, and Accurate Current-Sensing Technique for High-Performance Switching Regulators." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/16164.
Повний текст джерелаMolepo, Seaga Abram. "A multilevel inverter for DC reticulation." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/53253.
Повний текст джерелаENGLISH ABSTRACT: This report presents the design and development of a multilevel inverter for DC reticulation. Two main multilevel inverter topologies are introduced and discussed. The research focusses on the flying capacitor multilevel topology, since it became evident that it is more suitable for DC reticulation than the diode clamped multilevel topology. A bootstrap power supply for the gate drive circuits of a multilevel inverter is developed and its feasibility verified experimentally. A self-starting auxiliary power supply, that aims at addressing the power supply problem of DC to AC and DC to DC converters, is designed and its functionality demonstrated on a flying capacitor multilevel inverter. An FPGA based digital controller for implementing the inverter's control algorithms is also discussed. This controller incorporates a feed-forward output voltage regulation technique. Experimental results obtained with the four-level flying capacitor multilevel inverter, using the FPGA based digital controller and the self-starting auxiliary power supply, are presented in this report.
AFRIKAANSE OPSOMMING: In hierdie verslag word die ontwerp en ontwikkelling van 'n multivlak omsetter vir GS retikulasie bespreek. Twee hoof multivlak omsetter topologië word voorgestel en bespreek. Die navorsing fokus op die "vlieënde-kapasitor" multivlak topologië omdat dit duidelik geword het dat dit 'n beter opsie is vir die GS retikulasie as die diode-klamp multivlak topologië. 'n Kragbron vir die hekaandryfbane van die multivlak omsetter is ontwikkel en die werking daarvan is met experimentele toetse bevestig. 'n Self-begin kragbron, wat die probleem van die kragtoevoer aan die GS na WS en die GS na GS omsetters aanspreek, is ontwerp en die funksionaliteit is gedemonstreer met die "vlieënde-kapasitor" multivlak . omsetter. 'n Digitale beheerder, gebaseer op 'n FPGA, wat gebruik word om die omsetter se beheer algoritmes te implementeer, word ook bespreek. Hierdie beheerder inkorporeer 'n vorentoe-voer uittree spannings regulasie tegniek. Eksperimentele resultate wat gekry is met 'n vier-vlak "vlieënde-kapasitor" multivlak omsetter, wat van die FPGA gebaseerde digitale beheerder en die self-begin kragbron gebruik maak, word ook in die verslag bespreek.
Gunaydin, Zekiye. "Analysis And Design Of A Cuk Switching Regulator." Master's thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/12610606/index.pdf.
Повний текст джерелаZrikem, Nezha. "Circuiti per il miglioramento della qualità di sorgenti dc." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/8103/.
Повний текст джерелаPapargyris, Loukas. "Mécanismes de génération des macrophages immunorégulateurs humains : rôle de l’axe IL-27 / Adénosine / PGE2 The ecto-ATPDase CD39 is involved in the acquisition of the immunoregulatory phenotype by M-CSF-macrophages and ovarian cancer tumor-associated macrophages: Regulatory role of IL-27 Faecalibacterium prausnitzii Skews Human DC to Prime IL10-Producing T Cells Through TLR2/6/JNK Signaling and IL-10, IL-27, CD39, and IDO-1 Induction." Thesis, Angers, 2019. http://www.theses.fr/2019ANGE0038.
Повний текст джерелаThe purpose of the present thesis is to study the molecular mechanisms associated with the polarization of human macrophages towards an immunoregulatory phenotype, similar to that of tumor associated macrophages (TAM). Laboratory data have shown the role of IL-27 in this process, mostly by its capacity to modulate CD39 expression, which controls, at least in part, the acquisition of an immunoregulatory phenotype by human macrophages.The purpose of this work was to specify the molecular mechanisms involved in the acquisition of the regulatory phenotype, downstream IL-27. The results confirm the central role of adenosine, and therefore of the ectonucleotidase CD39, and identify the molecule PGE2 in the functional polarization of immunoregulatory macrophages. These data confirm the importance of IL-27 in the generation of human immunoregulatory macrophages and specify the involved molecular mechanisms. Over the long term, these results will allow to evaluate new strategies in the treatment of solid tumors, whose local immunosuppression is associated with a strong infiltrate of CD39-expressing macrophages
Sammons, Wendy L. "Generation and characterization of an attenuated mutant in a response-regulator gene of Francisella tularensis live vaccine strain (LVS)." [Tampa, Fla.] : University of South Florida, 2007. http://purl.fcla.edu/usf/dc/et/SFE0002268.
Повний текст джерелаDuz, Aleksei. "Modul pro řízení stejnosměrných motorů." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2020. http://www.nusl.cz/ntk/nusl-413030.
Повний текст джерелаWu, Jia. "Implementation of a 100kW Soft-Switched DC Bus Regulator Based on Power Electronics Building Block Concept." Thesis, Virginia Tech, 2000. http://hdl.handle.net/10919/32468.
Повний текст джерелаMaster of Science
Kadic, Safet, Alen Kazazic, and Florim Mustafa. "Exempel på användning av LabVIEW vid : mätning, reglering och signalbehandling." Thesis, Växjö University, School of Mathematics and Systems Engineering, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-636.
Повний текст джерелаArbetet handlar om hur man med hjälp av LabVIEW 8.0 kan lösa olika uppgifter. Uppgifterna löses med hjälp av ett DAQ-kort. DAQ-kortet gör det möjligt att mata in signaler, som sedan behandlas efter behov i programmet och därefter skickas ut genom DAQ- kortet till olika komponenter som man vill styra. DAQ-kortet klarar att behandla både analoga och digitala signaler. LabVIEW 8.0 och dess historia, DAQ-kortet samt de olika processerna/uppgifter beskrivs mer utförligt i arbetet.
Jeong, Timothy. "Zero Voltage Switching Hybrid Voltage Divider Converter." DigitalCommons@CalPoly, 2021. https://digitalcommons.calpoly.edu/theses/2290.
Повний текст джерелаAhmed, Muhammad Swilam Abdelhaleem. "Highly-efficient Low-Noise Buck Converters for Low-Power Microcontrollers." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1542277717997166.
Повний текст джерелаWerkstetter, Mario. "Hocheffizienter DC/DC-Wandler auf Basis von GaN-Leistungsschaltern für Hochleistungs-Leuchtdioden im Kraftfahrzeug." Universitätsverlag der Technischen Universität Chemnitz, 2017. https://monarch.qucosa.de/id/qucosa%3A20870.
Повний текст джерелаThis thesis deals with the research of possibilities for maximising efficiency of current-regulating DC/DC-Converters for driving high-power-LEDs in passenger-car- and motorcycle-lighting-devices. The ambition is to reduce weight and energy-consumption of the electronic-control-units, to contribute to reach the continuously decreasing target-values for vehicle-emissions. Therefor different approaches in topology, components, design and operating mode are considered. A key-challenge for the circuit-design is the common-part-strategy for usage in many individual vehicle-headlamp-systems with a wide range of output-current and LED-string-voltages. Basis for the reduction of power-losses is the simplification of the converters topology in terms of quantity of components. This is achieved by using the 48 V -vehicle-electrical-system as voltage-supply and a step-down-topology. Mainpart of this research is about the potential benefits of applying novel Galliumnitride High-electron-mobility-transistors (GaN-HEMTs) instead of silicon MOS-FETs. Initially this is done by calculations and parasitic-afflicted, timevariant circuit-simulations. Already in hardswitching operation under conventional switching-frequencies significant improvements in converter-efficiency can be achieved. Furthermore the advantages of higher switching-frequencies, offered by the GaN-transistors, are investigated. Up to 20 times higher switching-frequencies necessitate a resonant operating mode of the circuit (Zero-voltage-switching) and the use of an aircoil as main-inductor. On ECU-level power-losses can be reduced down to less than one third, which enables a more simplified and compact housing-concept, so that the overall weight can drop to about the half. Finally the designed circuit is build up in a prototype and the functional capability is verified in ZVS-mode with up to 10 MHz switching-frequency.
Jong, Owen. "Multi Resonant Switched-Capacitor Converter." Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/88019.
Повний текст джерелаMS
Following the recent trend, most internet services are moving towards cloud computing. Large data applications and growing popularity of cloud computing require hyperscale data centers and it will continue to grow rapidly in the next few years to keep up with the demand [4]. These cutting-edge data centers will require higher performance multi-core CPU and GPU installations which translates to higher power consumption. From 10MWatts of power, typical data centers deliver only half of this power to the computing load which includes processors, memory and drives. Unfortunately, the rest goes to losses in power conversion, distribution and cooling [5]. Industry members look into increasing backplane voltage from 12V to 48V in order to reduce distribution loss. This thesis proposes a novel Resonant Switched-Capacitor Converter using Multiple Resonant Frequencies to accommodate this increase of backplane voltage.
Chewele, Youngie Klyv. "Model predictive control of AC-to-AC converter voltage regulator." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86339.
Повний текст джерелаENGLISH ABSTRACT: The development of fast and efficient processors, programmable devices and high power semiconductors has led to the increased use of semiconductors directly in the power supply path in order to achieve strict power quality standards. New and advanced algorithms are used in the process and calculated on-line to bring about the required fast response to voltage variations. Losses in high voltage semiconductors increase with increased operating frequencies. A balance between semiconductor power losses and power quality is achieved through control of power semiconductor switching frequencies. A predictive control algorithm to achieve high power quality and limit the power losses in the high power semiconductor switches through switching frequency control is discussed for a tap switched voltage regulator. The quality of power, voltage regulator topology and the control algorithm are discussed. Simulation results of output voltage and current are shown when the control algorithm is used to control the regulator. These results are verified by practical measurements on a synchronous buck converter.
AFRIKAANSE OPSOMMING: Die ontwikkeling van vinnige en doeltreffende verwerkers, programmeerbare toestelle en hoëdrywings halfgeleiers het gelei tot 'n groter gebruik van halfgeleiers direk in die kragtoevoer pad om streng elektriese toevoer kwaliteit standaarde te bereik. Nuwe en gevorderde algoritmes word gebruik in die proses en word aan-lyn bereken om die nodige vinnige reaksie tot spanningswisselinge te gee. Verliese in hoë-spannings halfgeleiers verhoog met hoër skakel frekwensies. 'n Balans tussen die halfgeleier drywingsverliese en spanningskwalteit is behaal deur die skakel frekwensie in ag te neem in die beheer. 'n Voorspellinde-beheer algoritme om ‘n hoë toevoerkwaliteit te bereik en die drywingsverliese in die hoëdrywingshalfgeleier te beperk, deur skakel frekwensie te beheer, is bespreek vir 'n tap-geskakelde spanning reguleerder. Die toevoerkwaliteit, spanningsreguleerder topologie en die beheer algoritme word bespreek. Simulasie resultate van die uittree-spanning en stroom word getoon wanneer die beheer algoritme gebruik word om die omsetter te beheer. Hierdie resultate is deur praktiese metings op 'n sinkrone afkapper.
Gavagsaz, Ghoachani Roghayeh. "Comportement dynamique non-linéaire dans les convertisseurs statiques : régulateurs de courant et stabilité des réseaux DC." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0102/document.
Повний текст джерелаThis thesis discusses the study of dynamic behavior in power electronics systems. The nature of cycles defined by the state variables of the system can be settled either by a bifurcation diagram or by Floquet multipliers obtained from the discrete model of the converter. However, for certain structures of static converters, a discrete model cannot be obtained without introducing large assumptions. The flip bifurcations (fast-scale) cannot be predicted by the averaged model whereas they appear in many statics converters. A new formulation of a continuous averaged model is presented to estimate the first bifurcation point (flip, Hopf ...). The proposed methodology is applied to a boost converter, operated in continuous conduction mode, controlled by different types of fixed frequency switching current controllers. Then, this averaged model is used for the design of the current controller parameters associated with an active filter system. The variables obtained by the proposed model have been validated by numerical simulation and experimental results. Methods of analysis of limit cycles are extended to study the stability of DC networks when the cutoff frequency of the LC filter between the voltage source and the converter is close to the switching frequency of converters. Different discrete-time models have been developed in order to consider whether to use sampled or no-sampled converter control
Štaffa, Jan. "Jednofázový pulzní měnič DC/AC s digitálním řízením." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2009. http://www.nusl.cz/ntk/nusl-217881.
Повний текст джерелаRégnier, Paul. "Effet des interactions homéostatiques entre cellules dendritiques, lymphocytes effecteurs et régulateurs sur les réponses immunitaires anti-tumorales : étude du rôle de différentes cellules dendritiques in vivo chez la souris, et étude algorithmique des relations complexes entre transcriptome tumoral, populations immunitaires et survie in silico chez les patients A paradoxical role for Flt3 ligand in tumor immune response reveals homeostatic control of NK and treg cells by dentritic cells Tumor infiltration by immune cells favors patient survival in some cancers bur is highly detrimental in immune-privileged sites." Thesis, Sorbonne Paris Cité, 2018. https://wo.app.u-paris.fr/cgi-bin/WebObjects/TheseWeb.woa/wa/show?t=2244&f=15657.
Повний текст джерелаThe cancer, one of the main causes of death in the world, can appear in almost any type of tissue, and is characterized by an anarchic proliferation of cells and the establishment of a tolerogenic immune response favouring the tumour growth, leading to low efficiency of drug interventions. Dendritic cells (DCs), real sentinels of the body, seem to play a role in the establishment of both efficient anti-tumoral immune response and tolerance against cancer. Nevertheless, the role of the different DCs subtypes in the tumoral development stays poorly known. During this thesis, I studied different dendritic and lymphocytic cellular actors, their relationships and their involvement in the immune response or tolerance to tumours. During the first part of my thesis, I studied the effect of the artificial modulation of DCs homeostasis on other immune cells and also on anti-tumoral response in vivo in mice. I proved the existence of a paradoxical role of the Flt3-L (FL) cytokine - a growth factor essential to the differentiation and the homeostasis of classical/conventional dendritic cells (cDCs) and plasmacytoid dendritic cells (pDCs) - on the B16 melanoma growth. In fact, its overexpression or absence both lead to a better control of the tumoral development, accompanied by an increased survival of mice. FL deficiency induces, together with the loss of both cDCs and pDCs, a drastic reduction of regulatory T lymphocytes (Tregs) protecting the tumour, and also a global reinforcement of the anti-tumoral adaptive immune response via helper T lymphocytes. Its overexpression induces an increase of the numbers of cDCs and pDCs, and despite a raised presence of Tregs, also a strong intra-tumoral recruitment of activated natural killer (NK) cells, one of the major actors of the anti-tumoral innate response. The study of cDCs-deficient mice allowed me to demonstrate the existence of a DCs-mediated control of the NK cells homeostasis. Furthermore, the combination of both FL treatment and antibody-mediated Tregs depletion has an exacerbated therapeutic effect in mice. Next, using bioinformatic analysis of transcriptomes of 35 different cancer types, I showed that the FL paradox also exists in humans, at least for some cancers, and that gene signatures specific of DCs subsets can be correlated in a paradoxical, beneficial or detrimental manner to survival. In parallel, I evaluated the presence of several immune cells in the tumour infiltrate and their effects on patients survival. Thanks to R language algorithms I developed, I was able to analyse for each studied cancer the immune cell populations-specific gene signatures and the most involved or dysregulated genes and biological functions (pathways) in the control of the 5 years survival of patients. My results indicate that the immune cells of the tumour infiltrate can play, according to the cancer, a beneficial or deleterious role. This immune infiltrate and the associated pathways were generally of bad prognosis in cancers of immune-privileged organs, but on the other hand were beneficial in skin and breast cancers. For each cancer type, I determined the individual impact on survival of several types of immune cells and established correlations between involved pathways and some of these cell populations. Altogether, the results allow to better understand the complex relationships between each cancer and the associated immune infiltrate, and will later lead to help the development of immunotherapeutic strategies more adapted to a given tumour environment, by targeting the immune populations that could really impact the survival of patients
Januška, Adam. "Model laboratorního pohonu pro výukové účely." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2020. http://www.nusl.cz/ntk/nusl-413132.
Повний текст джерелаHuang, Bin. "Convertisseur continu-continu à rapport de transformation élevé pour applications pile à combustible." Thesis, Vandoeuvre-les-Nancy, INPL, 2009. http://www.theses.fr/2009INPL021N/document.
Повний текст джерелаThis work deals with the study, design and building of a DC-DC converter, which is associated with a fuel cell source. According to the application, this converter should have a high voltage ratio which is about 12, and it is able to limit the ripple current of source below 1% of the maximum average current. A cascaded structure composed by two converters has been chosen and allows obtaining a high voltage ratio. The first stage is an interleaved Boost associated with a L-C input filter, to reduce ripple of the current delivered by the source. The second stage is a three-level Boost which reduces the voltage stress of the switches, thereby reducing losses of the converter. The control of the converter is defined basing on the use of a non-linear regulator. Thanks to use the flatness control, the global control is realized through the regulation of the intermediate voltage and of the power transited to the load. Finally, a small power test converter (3 kW) has been realized, in order to validate the converter operation and the proposed control
Netáhlo, Tomáš. "Palubní multifunkční jednotka pro motocykly." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219822.
Повний текст джерелаHess, Lukáš. "Návrh dvoukolového autonomního robota." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230806.
Повний текст джерелаFreitas, Pedro Augusto Ramos de. "Proposta de um compensador sériie de tensão de elevada dinâmica para a correção da tensão instantânea da carga diante de afundamentos ou elevações da tensão da rede elétrica." Universidade Federal de Uberlândia, 2014. https://repositorio.ufu.br/handle/123456789/14580.
Повний текст джерелаEste trabalho propõe dois novos arranjos topológicos que consistem em se conectar a alimentação CA em série com dois conversores CC, um para operar durante o semiciclo positivo e o outro durante o semiciclo negativo. Vale ressaltar que estes conversores CC em série, em um caso são conversores Buck EIE e no outro um conversor Buck. Os resultados obtidos com ambos os arranjos são analisados e comparados. A estratégia de controle é desenvolvida com o intuito de impor uma tensão de saída CA dentro dos limites impostos pelas normas de forma a mitigar os problemas associados com Sags e Swells da rede de alimentação CA. Os princípios de operação, os resultados experimentais e de simulação obtidos, tanto em regime permanente quanto em condições transitórias de operação, são apresentados e validados para um protótipo experimental de 1kVA. Por fim apresentam-se os trabalhos relacionados a esta dissertação que ainda estão em desenvolvimento, que são a compensação em multinível e a compensação trifásica.
Mestre em Ciências
Alepuz, Menéndez Salvador Simón. "Aportación al control del convertidor CC/CA de tres niveles." Doctoral thesis, Universitat Politècnica de Catalunya, 2004. http://hdl.handle.net/10803/6330.
Повний текст джерелаThis dissertation study, propose and carry out the main contributions in the field of three-level inverter control, using the topology Neutral-Point-Clamped, although results can be extended to other topologies and/or number of levels. A procedure for modelling is presented, based on line-switching functions, moving average operator and D-Q transformation. Then, the obtained models in D-Q frame contain complete information about system dynamics. Switching strategy is simple and can be considered as an extension of two-level sinusoidal PWM to three level. The system variables are not controlled by the switching strategy. In this work, all the system variables are controlled by the regulator, including DC-link balance. This control approach is different than the conventional one, where DC-link balance is achieved by means of a proper selection of redundant states in the switching strategy, and the other variables are controlled by the regulator. The regulator is based on the multivariable linear control technique LQR (Linear Quadratic Regulator), in combination with the non-linear adaptive control technique Gain Scheduling. Moreover, a methodology for the calculation of the controller is presented. This controller is versatile, open and adaptable. However, the controller can be built depending on the concrete specifications of each application. The controller is calculated by means of simulation using MatLab-Simulink. The mathematical models based on the switching functions of the converter give the best trade-off between simulation speed and precision. In order to validate the proposed controller, an experimental prototype has been designed and implemented. Experimental results show that the controller is useful and effective for the regulation of different loads and applications, even with non-linear loads, different operation points and variables to control, in steady-state and transitory operation. Dynamic response speed and quality are similar to other control systems in the literature. The DC-link balance control achieved is specially interesting. Furthermore, steady-state error is cancelled due to the robustness of the controller, even though significant deviation of different system parameters are present. The use of Gain-Scheduling in combination with LQR is effective, allowing the calculation of regulators with different control strategies. Good agreement between simulations and experimental results has been found. This result validates simulation models and the design method for the controller, based on simulations.
Alepuz, Menéndez Salvador Simón. "Aportació al control del convertidor CC/CA de tres nivells." Doctoral thesis, Universitat Politècnica de Catalunya, 2004. http://hdl.handle.net/10803/6330.
Повний текст джерелаThis dissertation study, propose and carry out the main contributions in the field of three-level inverter control, using the topology Neutral-Point-Clamped, although results can be extended to other topologies and/or number of levels. A procedure for modelling is presented, based on line-switching functions, moving average operator and D-Q transformation. Then, the obtained models in D-Q frame contain complete information about system dynamics. Switching strategy is simple and can be considered as an extension of two-level sinusoidal PWM to three level. The system variables are not controlled by the switching strategy. In this work, all the system variables are controlled by the regulator, including DC-link balance. This control approach is different than the conventional one, where DC-link balance is achieved by means of a proper selection of redundant states in the switching strategy, and the other variables are controlled by the regulator. The regulator is based on the multivariable linear control technique LQR (Linear Quadratic Regulator), in combination with the non-linear adaptive control technique Gain Scheduling. Moreover, a methodology for the calculation of the controller is presented. This controller is versatile, open and adaptable. However, the controller can be built depending on the concrete specifications of each application. The controller is calculated by means of simulation using MatLab-Simulink. The mathematical models based on the switching functions of the converter give the best trade-off between simulation speed and precision. In order to validate the proposed controller, an experimental prototype has been designed and implemented. Experimental results show that the controller is useful and effective for the regulation of different loads and applications, even with non-linear loads, different operation points and variables to control, in steady-state and transitory operation. Dynamic response speed and quality are similar to other control systems in the literature. The DC-link balance control achieved is specially interesting. Furthermore, steady-state error is cancelled due to the robustness of the controller, even though significant deviation of different system parameters are present. The use of Gain-Scheduling in combination with LQR is effective, allowing the calculation of regulators with different control strategies. Good agreement between simulations and experimental results has been found. This result validates simulation models and the design method for the controller, based on simulations.
Šoupal, Ondřej. "Programování mikrokontrolérů c2000 v programu MATLAB/Simulink." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2020. http://www.nusl.cz/ntk/nusl-413221.
Повний текст джерелаMasoud, Khalid Hasan. "Circuits and controls for grid-connected inverters." Thesis, Queensland University of Technology, 2002.
Знайти повний текст джерелаFedoric, Boris. "Generation of tolerogenic human DC through Rapamycin conditioning and genetic modification with HLA-G." 2009. http://hdl.handle.net/2440/56027.
Повний текст джерелаThesis (Ph.D.) -- University of Adelaide, School of Medicine, 2009