Дисертації з теми "Receptor assembly"
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Sagar, Rajeeve. "Self-assembly via hydrogen bonding." Thesis, University of Warwick, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247352.
Повний текст джерелаAtlason, Palmi por. "The folding and assembly of NMDA receptor subunits." Thesis, University of Oxford, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487137.
Повний текст джерелаSmith, Miriam Jane. "Studies of GABA_A receptor subunit assembly and processing." Thesis, University College London (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415891.
Повний текст джерелаTaylor, Pamela Mary. "Identification of assembly determinants in GABAâ†A receptor subunits." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394507.
Повний текст джерелаGoebel, Erich J. "Insights into the Activin Class: Mechanisms of Receptor Assembly and Specificity." University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin162316530833396.
Повний текст джерелаNadler, Laurie Sue. "GABA(A) receptor subunit expression and assembly in rat cerebellar neurons." Case Western Reserve University School of Graduate Studies / OhioLINK, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=case1057672368.
Повний текст джерелаBerglund, Jenny. "Structure-function studies of organelle assembly and receptor recognition in organelles assembled via the chaperone/usher pathway /." Uppsala : Dept. of Molecular Biology, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/a441.pdf.
Повний текст джерелаBlümmel, Anne-Sophie [Verfasser], and Matthias [Akademischer Betreuer] Müller. "Initial assembly steps of the twin-arginine translocation signal peptide receptor complex." Freiburg : Universität, 2016. http://d-nb.info/1135118256/34.
Повний текст джерелаLegate, Kyle R. Andrews D. W. "Characterization of the beta-subunit of the mammalian SRP receptor and its role in assembly of the SRP receptor /." *McMaster only, 2003.
Знайти повний текст джерелаSukumaran, Madhav. "Biophysical investigations of AMPA receptor N-terminal domain structure and function reveal mechanisms underlying receptor assembly, dynamics, and allosteric potential." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708278.
Повний текст джерелаSeidenkranz, Daniel. "Barbiturates and Modified Hamilton Receptors for Supramolecular Catalysis, Sensing, and Materials Applications." Thesis, University of Oregon, 2019. http://hdl.handle.net/1794/24194.
Повний текст джерелаThevenin, Damien. "Roles of transmembrane domains in the folding and assembly of the adenosine A2A receptor." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 170 p, 2007. http://proquest.umi.com/pqdweb?did=1260822171&sid=2&Fmt=2&clientId=8331&RQT=309&VName=PQD.
Повний текст джерелаCordier, Stefanie. "The role of the linear ubiquitin chain assembly complex (LUBAC) in death receptor signalling." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/14426.
Повний текст джерелаSchmidt, Ralf [Verfasser], and Frank [Akademischer Betreuer] Würthner. "Hamilton-Receptor-Mediated Self-Assembly of Merocyanine Dyes into Supramolecular Polymers / Ralf Schmidt. Betreuer: Frank Würthner." Würzburg : Universitätsbibliothek der Universität Würzburg, 2012. http://d-nb.info/1021645737/34.
Повний текст джерелаGerlach, Bjorn. "Identification and characterisation of the linear ubiquitin chain assembly complex (LUBAC) as a functionally important component of the CD40 receptor signalling complex." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/9117.
Повний текст джерелаEmmerich, Christoph H. "Biochemical and functional characterisation of the Linear Ubiquitin Chain Assembly Complex (LUBAC) as a component of the TNF-Receptor 1 signalling complex." Thesis, Imperial College London, 2010. http://hdl.handle.net/10044/1/6186.
Повний текст джерелаNelson, Kjell Erik. "Investigating cell adhesion to controlled surface chemistry via self-assembly of binary composition alkylthiol monolayers, streptavidin immobilization, and cell receptor ligand attachment /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/8051.
Повний текст джерелаLu, Thi Hong Thanh [Verfasser], Michael [Gutachter] Hollmann, and Stefan [Gutachter] Wiese. "Investigations on agonist specificity and heteromeric assembly of Arabidopsis thaliana glutamate-like receptor (AtGLR) subunits / Thi Hong Thanh Lu ; Gutachter: Michael Hollmann, Stefan Wiese." Bochum : Ruhr-Universität Bochum, 2017. http://d-nb.info/1123283524/34.
Повний текст джерелаChen, Senbin. "Synthesis of original block copolymers by combination of RAFT polymerization and supramolecular self-assembly." Thesis, Lyon, INSA, 2012. http://www.theses.fr/2012ISAL0034.
Повний текст джерелаThis work dealt with the preparation and the study of supramolecular block copolymers based on hydrogen-bonding between homocomplementary or heterocomplementary stickers. The synthetic strategy was based on the combination of RAFT-mediated controlled radical polymerization and supramolecular chemistry. In the Chapter 2, we developed a strategy relying on the design of RAFT agents bearing thymine/diaminopyridine (DAP) recognition pairs and capable to grow well-defined miktoarm star supramolecular copolymers. To further extend the scope of H-bonding RAFT agents, in the Chapter 3, we also investigated the preparation of RAFT agents functionalized with motifs exhibiting very high binding constants. The Hamilton/barbiturate couple (log(K)≈4-5) was selected to generate more stable supramolecular block copolymers. Aiming at elaborating original associating macromolecules and at simplifying the strategy of synthesis, we finally explored the preparation ABC triblock supramolecular copolymers based on PA11 oligomers (OPA11) in Chapter 4. Ligation of a relevant dithiobenzoate group on the oligomers afforded oligomeric RAFT agents that allow for the preparation of ABC triblock supramolecular copolymers, where A is semi-crystalline, B in rubbery state and C in glassy state. Studies on the incorporation of such copolymers in epoxy networks are under progress
Harish, S. "Transcriptional Regulation By Nuclear Receptor Homodimers Binding To The Direct Repeat Motif DR1 : Investigations In An in vitro Transcription System Derived From Rat Liver Nuclear Extracts." Thesis, Indian Institute of Science, 2000. http://hdl.handle.net/2005/164.
Повний текст джерелаPennini, Meghan E. "Toll-like Receptor 2-dependent Inhibition of Interferon gamma Signaling by Mycobacterium tuberculosis." Connect to text online, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=case1152115234.
Повний текст джерелаAsencio, Hernandez Julia. "Novel approaches in NMR and biophysics for the study of complex systems : application to the N-terminal domain of the androgen receptor." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAJ013/document.
Повний текст джерелаMy PhD project was focused on the development of methods for the analysis of complex systems and their biophysical characterization. This includes the study of large chemical libraries, self assembly systems, protein-ligand interaction studies and disordered biological systems. A wide range of biophysical methods were used for this purpose. Specially, Nuclear Magnetic Resonance(NMR) but also other techniques such as mass spectrometry, circular dichroism (CD), electron microscopy (EM) and small angle X-ray scattering (SAXS). The N-terminal Domain of the Androgen Receptor is studied as an example of a complex system. This region plays an important role in receptor activity, and is also described as being intrinsically disordered. The results obtained during my thesis shown a short conserved region involved in the amyloid fibers formation under oxidative conditions. These results open new possibilities to understand the mechanism of the AR activity
Nagarajan, Naveen. "Molecular mechanisms of AMPA and kainate receptor gating and its implication in synaptic transmission." Doctoral thesis, [S.l.] : [s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965898768.
Повний текст джерелаKilb, Michael [Verfasser], Bodo [Akademischer Betreuer] Laube, and Ralf [Akademischer Betreuer] Galuske. "The role of the human glycine receptor transmembrane domains for the function, assembly and allosteric modulation by the general anesthetic propofol and closely related derivates / Michael Kilb ; Bodo Laube, Ralf Galuske." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2016. http://d-nb.info/1115856502/34.
Повний текст джерелаGuo, C. "Trafficking and assembly of P2X receptors." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599788.
Повний текст джерелаQuintero-Martinez, Adrian. "Assembly and selectivity of asialoglycoprotein receptors." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9232.
Повний текст джерелаCamiolo, Salvatore. "Anions in supramolecular chemistry : binding, sensing and assembly." Thesis, University of Southampton, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.252044.
Повний текст джерелаBofinger, Robin. "Photocontrolled biomimetic communication between molecules and nanosystems in confined compartments." Thesis, Bordeaux 1, 2013. http://www.theses.fr/2013BOR14933/document.
Повний текст джерелаThe thesis focuses on the study and design of novel photoactive molecules and their application as labeling agents, fluorescent molecular Ca2+-sensors and photolabile Ca2+-decaging agents in aqueous media and organized supramolecular assemblies. The designed fluorophores are based on boron-dipyrromethene (BODIPY) bearing hydrophobic chains or a reactive group like an azide or a perfluorophenyl moiety. Biocompatible calcium receptors have been prepared harnessing the fluorescence properties of BODIPY, naphthalimide and furan fluorophores. The development of self-assembled multicompartmentalized architectures, namely fluorocarbon vesicles in giant polymersomes is reported and the system has been used to create white light emission in confined microdomains. The Ca2+-based ion transfer ion the confined polymer compartments between individual fluorinated vesicles has been studied. The ion transfer in between vesicles in polymer microcompartments has been established as an artificial prototype system for cellular communication
Doward, Anne Isabel. "Assembly and trafficking of nicotinic and 5HT₃ receptors." Thesis, University College London (University of London), 2005. http://discovery.ucl.ac.uk/1444630/.
Повний текст джерелаLansdell, Stuart John. "Folding and assembly of neuronal nicotinic acetylcholine receptors." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298829.
Повний текст джерелаPapadakis, Michalis. "Assembly and trafficking of NMDA receptors : a biochemical approach." Thesis, University College London (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.415341.
Повний текст джерелаBerry, Neil. "Self-assembly of transition metal dithiocarbamate receptors for ionic guest species." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.270002.
Повний текст джерелаBaragli, Alessandra. "Assembly and function of multimeric adenylyl cyclase signalling complexes." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111888.
Повний текст джерелаLiu, Yuan. "Acyclic and Macrocyclic Transition Metal Receptors for Anion : Recognition and Pseudorotaxane Assembly." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.504425.
Повний текст джерелаPratt, Michelle. "Metal-directed self-assembly and anion recognition properties of transition metal-based receptors." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269331.
Повний текст джерелаMcConnell, Anna J. "Heteroditopic calix[4] arene based receptors for ion-pair recognition and mechanical bond assembly." Thesis, University of Oxford, 2010. https://ora.ox.ac.uk/objects/uuid:92d46010-5708-4f52-8075-0bded70a2203.
Повний текст джерелаSMUKSTE, INESE. "ARTIFICIAL RECEPTORS FOR MOLECULAR RECOGNITION OF AMINO ACIDS, PEPTIDES AND CARBOHYDRATES." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1029757614.
Повний текст джерелаPettersen, Jade Kristin. "Preparation and properties of self-assembled resorcinarene monolayers." Thesis, Curtin University, 2010. http://hdl.handle.net/20.500.11937/933.
Повний текст джерелаNandadasa, Sumeda A. "Cadherin mediated F-actin assembly and the regulation of morphogenetic movements during Xenopus laevis development." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1276953030.
Повний текст джерелаMeddows, Elisabeth. "Identification of the molecular determinants important in the assembly of N-methyl-D-aspartate (NMDA) receptors." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365682.
Повний текст джерелаDry, Emily Fiona Valentine. "Exploration of the dynamic chemistry of a subcomponent self-assembled dicopper(I) anion receptor." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708170.
Повний текст джерелаCharlesworth, Scott. "Design of photo-switchable self-assembled monolayers for the study of protein-receptor interactions." Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3847/.
Повний текст джерелаOshovsky, Gennady Veniaminovich. "Cavitand-based anion receptors and self-assembled (hemi)capsules in polar competitive media." Enschede : University of Twente [Host], 2006. http://doc.utwente.nl/55450.
Повний текст джерелаLiang, Chih-Kai. "Photocontrôle d'événements de reconnaissance moléculaire au sein de récepteurs greffés sur des surfaces : vers des ardoises supramoléculaires." Thesis, Bordeaux 1, 2012. http://www.theses.fr/2012BOR14645/document.
Повний текст джерелаAnthracene-appended photoactive barbiturate receptors possessing various anchoring groups are synthesized and characterized in view of transferring their photocontrolled binding properties onto substrates through various surface grafting techniques, such as amide bond formation, direct thioacetate linkage, or post click reaction modification. The photophysical and photochemical properties of the synthesized receptors were investigated in solution using variable temperature fluorescence, lifetime measurement and reaction quantum yield measurements. Receptor-modified gold substrates were characterized using ellipsometry, contact angle, AFM and PM-IRRAS experiments. The results showed that it is possible to reversibly modulate the binding properties of the anthracene-appended receptors through a combination of the irradiation with light (365nm) and heat (80℃)
Skehan, Brian M. "Functional Elements of EspFu, an Enterohemorrhagic E. coli Effector that Stimulates Actin Assembly: A Dissertation." eScholarship@UMMS, 2009. https://escholarship.umassmed.edu/gsbs_diss/443.
Повний текст джерелаJeamet, Emeric. "Études structurales et propriétés de reconnaissance d'objets auto-assemblés." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSE1024/document.
Повний текст джерелаSince the 1990s, dynamic combinatorial chemistry has allowed the discovery and preparation of new synthetic receptors from simple building blocks under thermodynamic control. In this context, we have recently described a new family of dynamic para cyclophanes, the so-called dyn[n]arenes. These macrocycles, made from functionalized 1,4-bisthiophenolic building blocks, could be obtained on a gram scale from a simple purification procedure, and without any chromatography. Their synthetic accessibility allows us to study the driving forces behind their self-assembly, as well as their molecular recognition properties towards ionic guest molecules. Experimental and computational experiments were also conducted to reveal the subtle physical phenomena that are responsible for the remarkable selectivity and affinity observed between a poly-anionic dyn[4]arene and a series of a,?-alkyl-diamines. During these previous studies, we rediscovered a simple synthetic route towards a family of molecules that is unexploited so far: the dithiocins. The functionalization of these molecular objects has been explored in order to generate versatile platforms for biological applications
Marshall, Tracey. "Dynamic chemistry : nucleobase recognition by synthetic receptors and cis-trans acylhydrazone isomerism." Thesis, Bordeaux 1, 2012. http://www.theses.fr/2012BOR14477/document.
Повний текст джерелаDynamic chemistry: nucleobase recognition by synthetic receptors and cis-trans acylhydrazone isomerism. This work deals with the development of molecular systems which can adapt upon the addition of substances that act as templates. This approach enables one major species to be identified from a mixture of compounds through the use of dynamic combinatorial chemistry (DCC). The first part of my PhD included the use of a single stranded DNA (ssDNA) as a template for information transfer via the self-assembly of receptors without the need for enzymes. New water soluble adenine and guanine receptors (A and G clamps) were designed and synthesised for this purpose. Nuclear magnetic resonance (NMR) titration studies were carried out to calculate the binding affinity and as a proof of specific and efficient recognition. An assessment in water via circular dichroism (CD) and UV temperature melting (Tm) studies was carried out. This tested the ability for self-assembly between the clamps and a ssDNA template and the strength of the cooperative process respectively. The second part of my PhD focused on the self-sorting of acylhydrazone pyridine motifs and the interesting configurations they adopt. The feasibility to synthesise these acylhydrazone pyridine motifs (dimer, trimers and pentamers) was investigated. X-ray and NMR studies showed that the equilibrium was found to be biased in an unusual way, and the cis acylhydrazone pyridine isomer was observed
Giraudat, Jérôme. "Etude de l'organisation fonctionnelle des chaines polypeptidiques du récepteur nicotinique de l'acétylcholine." Paris 6, 1986. http://www.theses.fr/1986PA066403.
Повний текст джерелаChen, Pengkun. "Titania and silica based hybrid porous nanomaterials : from synthesis to applications." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAF010/document.
Повний текст джерелаMy PhD research focus on the synthesis, characterization and applications of silica, titania and zeolite based porous materials. Porous silica, titania and zeolite have been synthesized using different methodologies. Functionalized silica materials have been used for dye adsorption application which is useful for water treatment. A new cross-linked system and device have been created to enhance the adsorption ability and for large quantity of water treatment. By taking advantage of the pores, new method for Cu(0) cluster formation have been established. The photophysics of the Cu(0) clusters reduced from different copper source in different porous materials has been investigated. The use of the confinement for sensing has been demonstrated for small bio molecules, such as neurotransmitters. Several applications have been developed based on this artificial neurotransmitter receptors. Multi-functionalized mesoporous titania material has been used for bio-applications. Compare to the widely used silica material, its photoactivity could bring extra advantages. Finally, new types of hybrid organotitanium materials have been developed and their photocatalytic properties have been investigated
McClure, Barbara Jean. "Molecular Assembly of the Activated Granulocyte-Macrophage Colony-Stimulating Factor Receptor." Thesis, 2017. http://hdl.handle.net/2440/119329.
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