Дисертації з теми "RDN"
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Fuchs, Luise [Verfasser]. "Effekte der Hochfrequenzablation der sympathischen Nerven der Nieren (Renale Denervation RDN) bei Patienten mit therapierefraktärer, essentieller arterieller Hypertonie / Luise Fuchs." Ulm : Universität Ulm, 2019. http://d-nb.info/1194465935/34.
Повний текст джерела
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Довгаль, Максим Олегович. "Методологія балансування електроенергії в балансуючій групі та модель аналізу часових рядів для прогнозування ціноутворення". Master's thesis, КПІ ім. Ігоря Сікорського, 2020. https://ela.kpi.ua/handle/123456789/40832.
Повний текст джерелаАнотація:
Актуальність роботи. Балансування електроенергії в новому ринку
електричної енергії є одним з актуальних питань. Для їх мінімізації окрім
більш чіткішого прогнозування створюють балансуючі групи, тому був
розроблений метод балансування для максимального зменшення небалансів.
Також для подальшої закупівлі електроенергії створена модель аналізу
часових рядів для прогнозування ціноутворення.
Раціональність використання балансування електричної енергії багато в
чому залежить від обсягу споживання підприємства та наявності
Автоматизована система комерційного обліку електричної енергії (АСКОЕ) .
Найбільше ефективне балансування в балансуючій групі, де більшість
підприємств мають обсяг споживання 100-600 тис. кВт·год, тим самим це буде
вигідно для підприємств у яких менше або більше споживання від заданого
діапазону.
Також для зменшення втрать розглядається питання з фінансової точки
зору, а саме прогнозування ціноутворення. Для цього проводиться аналіз
часових рядів для визначення ціноутворення електричної енергії. Це дуже
ефективно для закупівлі електричної енергії на ринку добу наперед (РДН) та
внутрішньодобового ринку (ВДР).
Мета та завдання дослідження: зменшення небалансів
електроспоживання промислових підприємств, шляхом балансування
електроенергії в балансуючій групі та аналізу часових рядів для визначення
ціноутворення електричної енергії для закупівлі на РДН та ВДР для
прогнозування вигідності споживання.
1. Проаналізувати споживання та заявлений обсяг промислового
підприємства, який купує електричну енергію на оптовому, а у майбутньому і
на балансуючому ринку електричної енергії.
2. Оцінити вигідність для приєднання промислового підприємства до
балансуючої групи.
3. Розробити методику методи балансування електроенергії в
балансуючій групі.
4. Розробити модель аналізу часових рядів для прогнозування
ціноутворення на РДН.
6. Оцінити та перевірити якість роботи моделі шляхом порівняння
фактичних значень на період який прогнозується.
Об’єктом дослідження є небаланси та ціни електричної енергії.
Предмет дослідження: методи балансування електроенергії в
балансуючій групі та аналіз часових рядів для визначення ціноутворення
електричної енергії.
Методи дослідження. Розробки і дослідження проводилися на основі
теорії математичного моделювання, модель аналізу часових рядів для
прогнозування ціноутворення.
Наукова новизна одержаних результатів.
1. Розроблено методологія балансування електроенергії в балансуючій
групі.
2. Створена модель аналізу часових рядів для прогнозування
ціноутворення.
Практичне значення одержаних результатів.
Дослідження, що було проведене в роботі може бути використане:
- для зниження фінансових витрат підприємств, які виникають при
відхиленні фактичних обсягів електричного споживання від обсягів, заявле-
них до покупки на ринку електричної енергії, шляхом балансування
електроенергії в балансуючій групі;
- для прогнозування ціноутворення для подальших закупівель на ринках
або аукціонах;
- для вибору найбільш оптимального плану роботи підприємства у ви-
падку коли спрогнозована вигідна ціна .Relevance of work. Balancing electricity in the new electricity market is one of the pressing issues. In addition to more clearly forecasting, balancing groups have been created to minimize them, so a balancing method has been developed to maximize the reduction of imbalances. The rationality of the use of balancing electricity depends largely on the volume of consumption of the enterprise and the availability of the Automated System of Commercial Electricity Metering (ASCOE) . hour, thereby it will be beneficial for enterprises that have less or more consumption from a given range. Also, to reduce losses, the issue is considered from a financial point of view, namely forecasting pricing. To do this, the analysis of time series is carried out to determine the pricing of electricity . Purpose and research objectives: to reduce the imbalances of power consumption of industrial enterprises, by balancing electricity in the balancing group and analysis in time series to determine the pricing of electricity for purchase on RDN and VDR to predict the profitability of consumption. 1. Analyze consumption and the declared volume of industrial enterprise that buys electricity at wholesale, and in the future and in the balancing market of electricity. 2. Assess the profitability for joining the industrial enterprise in the balancing group. 3. Develop methods of balancing electricity in the balancing group. 4. Develop a model of time series analysis to predict the pricing of RDN. 6. Oto value and to revibrate the quality of the model by comparing the actual values for the period that is projected. The object of research is imbalances and prices of electric energy. Subject of research: methods of balancing electricity in the balancing group and analysis of time series to determine the pricing of electric energy. Research methods. Developments and researches were conducted on the basis of the theory of mathematical modeling, a model of time series analysis for forecasting pricing. Scientific novelty of the obtained results. 1. The etiology of balancing electricity in the balancing group was developed. 2. A model for analyzing time series for forecasting pricing has been created. The practical significance of the obtained results. The research that was conducted in the work can be used: - to reduce the financial costs of enterprises that arise when deviating the actual volumes of electricity consumption from volumes, stated - them to purchase electricity on the market, by balancing electricity in the balancing group; - to predict pricing for further purchases in markets or auctions; - to choose the most optimal plan of work of the enterprise in you - a paddock when the favorable price is predicted.
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Mureika, Evaldas. "Duomenų, surinktų iš HTML failų, publikavimo RDF formate metodika." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2012. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2012~D_20120813_151133-34115.
Повний текст джерелаАнотація:
Semantinis tinklas – tai duomenų tinklas, leidžiantis apjungti informaciją esančią įvairiuose šaltiniuose ir pavaizduoti visą surinktą informaciją kaip vientisą turinį. Semantiniame tinkle duomenys susieti ir prieinami per bendrąją tinko architektūrą, panaudojant URI adresus. Didžioji dalis duomenų yra neapjungti ir prienami atskiroms taikomosioms programoms. Apjungus šiuos įvairiuose šaltiniuose laikomus duomenis būtų sukurtas semantinis duomenų tinklas.
Duomenims panaudoti, aprašyti bei susieti kuriami įvairūs karkasai, leidžiantys pakartotinai dalintis duomenimis visose taikymo srityse, įmonėse bei bendrijose. Struktūrizuota semantinė informacija naudojama automatiškai arba rankiniu būdu ir apdorojama kompiuterių. Semantinio tinklo metodai ir technologijos leidžia kompiuteriams suprasti pasauliniame tinkle (angl.World Wide Web) laikomos informacijos reikšmę arba kitaip semantiką.
Semantinio tinklo technologijos panaudojamos:
1) duomenų integracijai, duomenų laikomų skirtingose vietose ir saugomų skirtingais formatais susiejimui;
2) resursų aptikimui ir klasifikacijai, sukuriant geresnį informacijos paieškos variklį;
3) tinklapių, svetainių ar skaitmeninių bibliotekų katalogavimui aprašant turinį, turinio ryšius;
4) sumaniųjų programinės įrangos agentų žinių mainams palengvinti;
5) turinio reitingavimui;
6) aprašant intelektualinės nuosavybės teises (tinklapiuose);
Semantiniotinklų taikymas bei technologijos technologijos yra dar labai naujos, neištirtos, neišbandytos... [toliau žr. visą tekstą]Semantic Network - is a data network of the information to combined from various sources and displayed as onesolid content. Data, in the Semantic networks is accessed using URIs, via a common network architecture. Semantic networks and technologies are still very new, unexplored, not tested inpractice and lacking of reference material. It isnecesery to analyzehow the technology is advanced and what technology and tools are used for semantic web application development. Objectives of this work: 1) To analyze how HTML data can be published; 2) To analyze the development of semantic web technologies; 3) To create an application automatically scanning the data from the HTML files; 4) To create an application that generates the OWL ontology of the relational database; 5) Apply semantic publishing for data; 6) To analize experimentaly HTML data colleting application and OWL generator.
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Auler, Luiz Telmo da Silva. "Ressonância magnética nuclear em supercondutores de alto Tc." Universidade de São Paulo, 1994. http://www.teses.usp.br/teses/disponiveis/76/76131/tde-08042014-142100/.
Повний текст джерелаАнотація:
Nesta tese investigamos o estado normal (T > Tc) dos Yba2Cu3O6+x supercondutores de alto Tc. As técnicas da RMN e RQN foram empregadas para estudar as respostas estática e dinâmica do sistema de spins eletrônicos em função da temperatura, para diversas concentrações de oxigênio: x = 0.5 (cristal 1), 0.92 (cristal 2), 0.94 (cristal 3) e 1.0 (cristais 4 e 5). Focalizando diferentes sítios nucleares a RMN pode fornecer uma informação mais rica da susceptibilidade dinâmica, X (q.w), abrangendo diferentes regiões da Zona de Brillouin (ZB). Com os sítios do 17O(2,3) e do 89Y sensoreamos a região próxima ao centro do ZB, q == 0, enquanto que com o sitio do Cu(2) exploramos o extremo do ZB, (q == QAF). Foi realizado um estudo comparativo da RMN dos sítios do Cu(2), do O(2,3) e do Y sobre o cristal 1. Da comparação entre os deslocamentos hiperfinos magnéticos do Y e do O(2,3) extraímos as contribuições orbitais e as constantes de acoplamento hiperfino do Y. A razão entre as relaxações spin-rede do O(2,3) e do Y mostrou-se independente da temperatura, e próxima do esperado teoricamente a partir das constantes hiperfinas no cenário do hamiltoniano de Mila e Rice. Questões como a dependência da taxa de relaxação spin-rede (T1-1) com a intensidade do campo e a anisotropia da susceptibilidade estática de spin foram estudadas sobre o cristal 2. Acima de Tc, para o Cu(2), não foi encontrada nenhuma dependência de T1 com a intensidade do campo. Os resultados sobre o Y indicam uma anisotropia da susceptibilidade e do tensor de acoplamento hiperfino. Uma extensa comparação entre os resultados da RMN e da Difusão Inelástica de Nêutrons (DIN) foi realizada sobre as mesmas amostras (cristais 4 e 5), fato inédito ate então. Propõe-se um modelo gaussiano para X\"~q,o», compatível com as experiências de nêutrons, no qual o comprimento de correlação ~ foi fixado pelos resultados da DIN sobre o cristal 2. Analisando a relaxação spin-spin do Cu(2), 63(T2g)-1, em função deste modelo, extraímos a susceptibilidade estática X\'(q=QAF) em unidades absolutas e encontramos um fator de Stoner X\'(q=QAF) / X\'(q=O) ~ 10. Da análise conjunta de 63(T1T)-1 e 63 (T2g)-1 obtivemos a energia característica das flutuações AF, rAF::::3:0meV, em excelente acordo com a DIN. Estes mesmos resultados permitiram evidenciar, exclusivamente através do RMN, quando ocorre a abertura de um gap de spin. Neste trabalho mostramos que resultados da DIN são compatíveis com a RMN para o sitio do Cu(2), porem, sérias dificuldades são encontradas para explicar os resultados sobre os sítios do Y e, principalmente, do O(2,3). As alternativas para este problema são discutidas. Os resultados obtidos nesta tese levaram ao estabelecimento de um diagrama de fase, segundo a RMN, do estado normal dos Yba2Cu3O6+x supercondutores, cobrindo do regime sub-dopado ao regime sobre-dopado, passando pela composição de dopagem ótima.The normal state(T > Tc) of the high Te superconducting Yba2Cu3O6+x was studied. The NMR and NQR techniques were employed in order to investigate the static and dynamic responses of the electronic spin system as function of temperature, for the following oxygen contents: x = 0.5 (crystal 1), 0.92 (crystal 2), 0.94 (crystal 3) e 1.0 (crystals 4 and 5). Focusing various nuclear sites the NMR could give a more rich information of the dynamical susceptibility, X(q,ffi), probing different regions of the Brillouin Zone (ZB). With 17O(2,3) and 89Y sites the BZ center, q:: 0, was studied, while with the Cu(2) site it was the BZ extreme, (q:: QAF) that was investigated. In crystal 1 we have compared the NMR of the Cu(2), O(2,3) and Y sites. From the comparison between the Y and O(2,3) magnetic hyperfine shift we have extracted the orbital contributions and the Y hyperfine coupling tensor. The ratio between the O(2,3) and Y nuclear spin lattice relaxation rate was found to be temperature independent, and its value was in fair agreement with what it was expected theoretically from the coupling constants within the picture of the Mila-Rice Hamiltonian. Problems such as the field intensity dependence of the spin-lattice -relaxation rate (T1-1) and the anisotropy of the static susceptibility where investigated in crystal 2. Above Tc, for the Cu(2) site, we have not found any field dependence of T1. Our results on the Y site indicate an anisotropy of both the static susceptibility and the Y coupling tensor. An extensive comparison between the NMR and the Inelastic Neutron Diffusion (IND) results was done in the very same samples, crystals 2 and 4. In accordance to neutron data a Gaussian model for X\"AF( q,ro) is proposed, in which the coherence length ~ was fixed by the IND results in crystal 2. Analyzing the Cu(2) nuclear spin-spin relaxation rate, 63(T2g)-1, as function of this model, we have extracted the staggered susceptibility X\'(q=QAF) in absolute units, finding a Stoner factor X \'( q=QAF) / X\'( q=O) ~ 10. From the analysis of 63(T1T)-1 together with 63(T2g)-1 we have obtained the AF characteristic energy, rAF ::::l 30meV, in excellent agreement with IND. These results provided us a powerful method to evidence the opening of a spin pseudo gap, exclusively from the NMR results. A consistent picture arise from the comparison between IND and the Cu(2) NMR. In contrast, it is hard to explain the Y and, specially, the O(2,3) results within this same picture. The theoretical alternatives to this puzzle are discussed. The whole set of results we have obtained led us to propose a NMR based phenomenological phase diagram for the normal state of the superconducting Yba2Cu3O6+x, covering from the under doped regime to the over doped regime, passing through the optimal doping.
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ESSAMPALLY, SURESH. "STUDYING THE INTERACTION OF ANTIFREEZE PROTEINS (TYPE I AND TYPE III) WITH THE PHOSPHOLIPID MONOLAYERS AT AIR/WATER INTERFACE." Cleveland State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=csu1197407755.
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Neves, Juliana Teixeira de Magalhães. "Características moleculares e identificação de Lactobacillus delbrueckii UFV H2b20." Universidade Federal de Viçosa, 2003. http://www.locus.ufv.br/handle/123456789/10679.
Повний текст джерелаАнотація:
Submitted by Nathália Faria da Silva (nathaliafsilva.ufv@gmail.com) on 2017-06-13T18:17:32Z
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resumo.pdf: 17263 bytes, checksum: 8e51a65fe7d8eecb448411acb64cf05b (MD5)Made available in DSpace on 2017-06-13T18:17:32Z (GMT). No. of bitstreams: 1 resumo.pdf: 17263 bytes, checksum: 8e51a65fe7d8eecb448411acb64cf05b (MD5) Previous issue date: 2003-02-20
Fundação de Amparo a Pesquisa do Estado de Minas Gerais
A estirpe probiótica Lactobacillus UFV H2b20, previamente classificada como Lactobacillus acidophilus por suas características de fermentação de açúcares, apresentou-se mais semelhante à espécie Lactobacillus delbrueckii, quanto à seqüência de rDNA 16S, o que levou ao questionamento acerca da identidade da linhagem. Para o esclarecimento da real classificação da linhagem, o método de hibridização DNA-DNA foi empregado. A linhagem apresentou 75,2% e 77,4% de reassociação com L. delbrueckii subsp. lactis (ATCC 12315) e L. delbrueckii subsp. delbrueckii (ATCC 9649), respectivamente. Dado que a homologia de 70% ou mais, por esse método, tem sido usada como padrão para agrupamento de bactérias em uma mesma espécie, sugere-se, aqui, que Lactobacillus UFV H2b20 seja, daqui para frente, denominado L. delbrueckii UFV H2b20. Identificada a linhagem, outro objetivo do trabalho era desenvolver um protocolo para detecção in situ de L. delbrueckii. Uma sonda de 26 nucleotídeos (SA) foi construída e testada com outras espécies de Lactobacillus relacionadas geneticamente entre si. Estes estudos demonstraram que a seqüência de assinatura (SA) estava presente em L. delbrueckii UFV H2b20, L. delbrueckii UFV H2b21, L. delbrueckii subsp. delbrueckii e L. delbrueckii subsp. lactis, o que indica ser ela eficaz para ser usada como sonda para rRNA 16S espécie-específica pelo método de FISH. A hipótese de existência de polimorfismos, levantada em trabalhos prévios no rDNA 16S da linhagem, foi confirmada após as análises dos segmentos de DNA clonados e selecionados do banco genômico construído para a linhagem L. delbrueckii UFV H2b20. As seqüências analisadas demonstraram, também, presença de segmentos correspondentes a quatro genes codificadores de rRNA 16S distintos, e seis segmentos distintos para uma mesma região de rRNA 23S, indicando seis operons putativos. Há evidência de, pelo menos, um operon putativo completo seguido de região codificadora de seis tRNAs. Não se detectou região espaçadora longa entre rDNA 16 e 23S.
Lactobacillus UFV H2b20, a probiotic strain, previously identified as Lactobacillus acidophilus due to its sugar fermentation pattern, was found to be more closely related to Lactobacillus delbrueckii regarding its 16S rDNA sequence. It was demonstrated by DNA-DNA hybridization that this strain presented 75.2% and 77.4% of reassociation with L. delbrueckii subsp. lactis ATCC 12315 and L. delbrueckii subsp. delbrueckii ATCC 9649, respectively. These results place Lactobacillus UFV H2b20 within the L. delbrueckii species, for 70% reassociation as measured by the method used has been a standard to cluster bacteria within the same species. A protocol for in situ detection of L. delbrueckii was developed by means of Fluorescent in situ Hybridization, FISH. A probe consisting of 26 nucleotides labeled with rhodamine was designed based on the signature sequence within the rDNA, and was tested against genetically related Lactobacillus species. A species- specific method was obtained capable of discriminating L. delbrueckii strains from other Lactobacillus species. Previous studies raised the hypothesis of polymorphism among the copies of 16S rDNA in L. delbrueckii UFV H2b20. This was confirmed by sequence analysis of rDNA from a gene library of this strain cloned in phage lambda and subcloned in pBluescript. Sequence analyses of cloned fragments demonstrated the presence of at least four distinct genes encoding 16S rRNAs. Distinct fragments containing 23S rRNA related genes indicated six putative rrn operons. One complete putative rrn operon displays a region encoding 6 different tRNAs. Long spacer regions between 16S and 23S rDNA were not detected.
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Stratmann, Dirk. "Nouvelles méthodes pour l'attribution de spectres RMN de protéines de structure tridimensionnelle connue." Paris 6, 2008. http://www.theses.fr/2008PA066667.
Повний текст джерелаАнотація:
Une condition préalable pour toute étude d’une protéine par RMN est l’attribution des résonances du spectre 15N-1H HSQC à leurs atomes correspondants du squelette peptidique. Un nouveau type de stratégie d’attribution exploite l’information donnée par une structure 3D déjà disponible de la même protéine ou d’une protéine homologue. Jusqu’à présent, les algorithmes, développés autour de cette stratégie, ont deux inconvénients majeurs : ils ne peuvent pas garantir l’exactitude de l’attribution et ils ne sont pas applicables à des protéines de grande taille. Dans un premier temps, il est montré que l’utilisation des couplages dipolaires résiduels (RDC) pour l’attribution basée sur la structure peut poser des problèmes, notamment liée à l’estimation du tenseur d’alignement. Une nouvelle méthode d’attribution basée sur la structure, nommée NOEnet, est présentée ici. NOEnet n’est pas basée sur les RDCs mais sur les effets Overhauser nucléaire (NOEs). RDCs, déplacements chimiques (CS) et presque tout type de donnée peuvent être inclus dans NOEnet grâce à une approche générale de filtre. NOEnet exploite le réseau de contraintes NOE HN-HN non ambiguës en réalisant une recherche exhaustive de tous les appariements possibles entre le réseau des NOEs et le réseau de la structure 3D. Son algorithme efficace de recherche complète garantit l’exactitude du résultat d’attribution. NOEnet a été testé avec succès sur plusieurs protéines jusqu’à 28 kDa, en utilisant uniquement des données NOE ou une combinaison de données NOE, RDC et CSA prerequisite for any protein study by NMR is the assignment of the resonances from the 15N-1H HSQC spectrum to their corresponding atoms of the protein backbone. A new type of assignment strategy exploits the information given by an already available 3D structure of the same or a homologous protein. Up to now, the algorithms that have been developed around this strategy have two important drawbacks: they cannot guarantee the accuracy of the assignment and they are not applicable to large proteins. First is shown that the use of residual dipolar couplings (RDC) for the structure based assignment can be problematic, especially the estimation of the alignment tensor is difficult. A novel structure based assignment approach, called NOEnet, is presented here. NOEnet is not based on RDCs but on Nuclear Overhauser Effects (NOEs). RDCs, chemical shifts (CS) and almost any kind of data can be included in NOEnet through a general filter approach. NOEnet exploits the network property of unambiguous HN-HN NOE constraints to realize an exhaustive search of all matching possibilities of the NOE network on the structural one. Its efficient complete search algorithm ensures the correctness of the assignment results. NOEnet has been successfully tested on several proteins up to 28 kDa, using only NOE data or a combination of NOE, RDC and CS data
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Geller, Alexander C. "Thermal Imaging of RDCs and the Characterization of an Operating Map for a Novel RDC Geometry." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin161368598622062.
Повний текст джерела
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Kern, Thomas. "Approches innovantes en RMN biomoléculaire : cinétiques moléculaires par RMN rapide et paroi bactérienne par RMN du solide." Phd thesis, Université Joseph Fourier (Grenoble), 2009. http://tel.archives-ouvertes.fr/tel-00825098.
Повний текст джерелаАнотація:
Les méthodes RMN multidimensionnelles requises pour l'obtention d'une résolution atomique élevée sont relativement couteuses en temps expéri- mental, ce qui complique considérablement leur application à l'analyse d'échantillons en temps réel. La première partie de cette thèse traite des pro- grès récents dans le domaine de l'acquisition rapide des spectres de RMN . La deuxième partie concerne la paroi cellulaire des bactéries Gram-négatives et Gram-positives. En raison de son poids moléculaire élevé et de son car- actère non cristallin, nous avons appliqué la RMN du solide pour l'étudier. La qualité exceptionnelle des spectres de RMN solide permet l'étude, à résolution atomique, de la structure et de la dynamique du peptidoglycane et des acides téchoïques qui se lient de manière covalente au peptidoglycan (WTA). La détermination des propriétés dynamiques du peptidoglycane est aussi utilisée pour étudier les interactions entre protéines et peptidoglycane et la complexation avec des ions divalents.
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Silva, Natalia de Sousa Teixeira e. "Dinâmica nucleolar e a herança epigenética dos genes ribossomais." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/11/11137/tde-11082014-174129/.
Повний текст джерелаАнотація:
O nucléolo é uma organela subnuclear formada pela atividade transcricional dos genes ribossomais 18S-5.8S-26S (rDNA 45S) e consequente biogênese dos ribossomos. A atividade destes genes resulta na região organizadora do nucléolo (NOR), na forma de uma constrição secundária em cromossomos metafásicos. As constrições secundárias se condensam progressivamente durante a mitose e se descondensam ao final da telófase quando a reestruturação do nucléolo se inicia. Genomas que apresentam mais de um locus de rDNA 45S deve apresentar, obrigatoriamente, pelo menos um par de NORs, enquanto os demais loci poderão ou não serem expressos. O controle da expressão dos genes ribossomais e a formação da cromatina nucleolar são modulados por eventos epigenéticos. Embora alguns pontos sobre o funcionamento dos genes ribossomais e a formação do nucléolo estejam bem estabelecidos, questões como o padrão de condensação da cromatina nucleolar durante a mitose, o padrão de funcionamento de sítios adicionais de genes ribossomais, o papel das modificações epigenéticas na dinâmica da cromatina nucleolar e na expressão do rDNA 45S e o mecanismo de herança dos genes ativos, permanecem abertas. A espécie Crotalaria juncea (Leguminosae-Papilionoideae), com 2n=2x=16 cromossomos, que possui um locus de rDNA 45S no braço curto do cromossomo 1, que sempre forma constrição secundária, e um sítio adicional com atividade facultativa no braço curto do cromossomo 4, é um excelente modelo para o estudo destas questões. No contexto apresentado, foram estudadas a dinâmica de condensação das NORs durante o ciclo celular e sua correlação com a atividade dos genes ribossomais, incluindo o locus adicional, e ainda o papel da metilação da citosina do DNA durante estes processos. Os resultados demonstram que a cromatina da região organizadora do nucléolo segrega em um estado descondensado durante a mitose, na forma de constrição secundária, ou seja, tal estrutura não se condensa durante a metáfase e não volta a se distender no início da telófase. Aparentemente, o que causa correlações equivocadas entre a atividade nucleolar e a observação morfológica da constrição secundária na metáfase é a contração forçada da cromatina da NOR causada por agentes antimitogênicos. Este modelo de segregação em um estado aberto pode ser explicado pela descrição de diversas proteínas que permanecem diretamente ligadas ou indiretamente associadas à região da NOR durante a mitose, funcionando como uma barreira física para a compactação. Ambos os sítios, principais e adicionais, do rDNA 45S presentes em Crotalaria juncea apresentam atividade transcricional, embora o locus do cromossomo 4 mostre atividade facultativa. Ao contrário do que foi anteriormente proposto, uma vez ativo, o locus adicional permanece descondensado durante todo o ciclo mitótico, seguindo o mesmo comportamento dos sítios principais. As constrições secundárias e a cromatina nucleolar são hipermetiladas em nível citológico, independentemente de sua atividade. A aparente hipometilação observada no rDNA 45S em cromossomos mitóticos e núcleos interfásicos se deve ao menor grau de compactação da região organizadora do nucléolo e, consequentemente, à baixa densidade de cromatina.The nucleolus is a subnuclear organelle formed as a result of transcriptional activity of ribosomal RNA genes 18S-5.8S-26S (45S rDNA) and subsequent ribosome biogenesis. This activity forms the nucleolar organizing region (NOR) as a secondary constriction in metaphase chromosomes. The secondary constrictions progressively condense during mitosis and decondense at the end of telophase, when nucleoli start to reassemble. Genomes presenting more than one 45S rDNA locus must have at least one pair of NOR bearing chromosomes, while other loci may be expressed or not. Ribosomal gene expression and nucleolar chromatin assembly are modulated by specific epigenetic events. Although some topics related to rDNA gene activity and nucleolus formation are well understood, questions such as the behavior of nucleolar chromatin condensation during mitosis, standard functions associated with rDNA additional sites, role of epigenetic modifications in nucleolar chromatin and 45S rDNA expression processes, and inheritance mechanism of active genes, remain to be solved. Crotalaria juncea (Leguminosae - Papilionoideae) has 2n=2x=16 chromosomes and carries a 45S rDNA locus at the short arm of chromosome 1, always presenting a secondary constriction, and an additional site with facultative activity at the short arm of chromosome 4, being an excellent model to resolve these questions. Thus, this study aimed to study NOR condensation dynamics during the cell cycle and its correlation with ribosomal gene activity, including the additional locus, while analyzing the role of rDNA cytosine methylation during this process. The results show that NOR chromatin segregate in a decondensed way throughout mitosis, as a secondary constriction. In other words, this structure does not condense during metaphase and the NOR is not reassembled at the beginning of telophase. Misinterpretations relating nucleolar activity with morphological observations of secondary constrictions, appear to be induced by the artificial contraction of NOR chromatin caused by antimitotic drugs. This segregation model in an open state may be supported by strong diversity of proteins that are maintained attached to NORs during mitosis, serving as a physic barrier for condensation. Both principal and additional 45S rDNA sites of C. juncea are transcriptionally active, although the additional locus in chromosome 4 presented facultative activity depending upon ribosomal request. Unlike what was previously proposed, once the additional site is activated, it remains in an open configuration throughout the cell cycle, similarly to principal site behavior. Secondary constrictions and nucleolar chromatin are hypermethylated at cytological level, regardless of their activity. The seeming hipomethylated state of 45S rDNA in interphase nucleus and mitotic chromosomes is due to a lower compaction level of nucleolar organizing regions and subsequent low chromatin density.
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Lazarus, Jens. "RDA und GND." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-39043.
Повний текст джерелаАнотація:
Zur Zukunft der Katalogisierung werden zur Zeit zwei große Themenkomplexe diskutiert. Einmal der Aufbau einer Gemeinsamen Normdatei (GND) und die Einführung eines neuen Regelwerks, „Resource Description and Access (RDA)“. Das Regelwerk soll die bislang geltenden RAK ablösen und nicht nur für Bibliotheken, sondern auch für Archive und Museen zur Verfügung stehen. Da die verschiedenen Normdateien auf unterschiedlichen Datenmodellen und Formaten basieren, wird an einer Zusammenführung der Normdatenbanken in eine einheitliche Normdatei gearbeitet.
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Spengler, Nike. "ren, skör, lögn." Thesis, Konstfack, Grafisk Design & Illustration, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-5233.
Повний текст джерелаАнотація:
A part of my world was turned upside down. Shortly before the project’s start I saw the doc- umentary Myten om mödomshinnan1, which was published on UR Play in 2011. Filmmaker Lotta Ekelund reveals that the hymen is a figment for many people during the movie, as it was for me. Ambiguity made me curious to explore the concept more deeply and motivated me to find a graphical solution for showcasing the bizarre falsehood, and to demonstrate the truth.
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Ticona, Herrera Regina Paola. "Towards RDF normalization." Thesis, Pau, 2016. http://www.theses.fr/2016PAUU3015/document.
Повний текст джерелаАнотація:
Depuis ces dernières décennies, des millions d'internautes produisent et échangent des données sur le Web. Ces informations peuvent être structurées, semi-structurées et/ou non-structurées, tels que les blogs, les commentaires, les pages Web, les contenus multimédias, etc. Afin de faciliter la publication ainsi que l'échange de données, le World Wide Web Consortium (ou W3C) a défini en 1999 le standard RDF. Ce standard est un modèle qui permet notamment de structurer une information sous la forme d'un réseau de données dans lequel il est possible d'y attacher des descriptions sémantiques. Ce modèle permet donc d'améliorer l'interopérabilité entre différentes applications exploitant des données diverses et variées présentes sur le Web.Actuellement, une grande quantité de descriptions RDF est disponible en ligne, notamment grâce à des projets de recherche qui traitent du Web de données liées, comme par exemple DBpedia et LinkedGeoData. De plus, de nombreux fournisseurs de données ont adopté les technologies issues de cette communauté du Web de données en partageant, connectant, enrichissant et publiant leurs informations à l'aide du standard RDF, comme les gouvernements (France, Canada, Grande-Bretagne, etc.), les universités (par exemple Open University) ainsi que les entreprises (BBC, CNN, etc.). Il en résulte que de nombreux acteurs actuels (particuliers ou organisations) produisent des quantités gigantesques de descriptions RDF qui sont échangées selon différents formats (RDF/XML, Turtle, N-Triple, etc.). Néanmoins, ces descriptions RDF sont souvent verbeuses et peuvent également contenir de la redondance d'information. Ceci peut concerner à la fois leur structure ou bien leur sérialisation (ou le format) qui en plus souffre de multiples variations d'écritures possibles au sein d'un même format. Tous ces problèmes induisent des pertes de performance pour le stockage, le traitement ou encore le chargement de ce type de descriptions. Dans cette thèse, nous proposons de nettoyer les descriptions RDF en éliminant les données redondantes ou inutiles. Ce processus est nommé « normalisation » de descriptions RDF et il est une étape essentielle pour de nombreuses applications, telles que la similarité entre descriptions, l'alignement, l'intégration, le traitement des versions, la classification, l'échantillonnage, etc. Pour ce faire, nous proposons une approche intitulée R2NR qui à partir de différentes descriptions relatives à une même information produise une et une seule description normalisée qui est optimisée en fonction de multiples paramètres liés à une application cible. Notre approche est illustrée en décrivant plusieurs cas d'étude (simple pour la compréhension mais aussi plus réaliste pour montrer le passage à l'échelle) nécessitant l'étape de normalisation. La contribution de cette thèse peut être synthétisée selon les points suivants :i. Produire une description RDF normalisée (en sortie) qui préserve les informations d'une description source (en entrée),ii. Éliminer les redondances et optimiser l'encodage d'une description normalisée,iii. Engendrer une description RDF optimisée en fonction d'une application cible (chargement rapide, stockage optimisée...),iv. Définir de manière complète et formelle le processus de normalisation à l'aide de fonctions, d'opérateurs, de règles et de propriétés bien fondées, etc.v. Fournir un prototype RDF2NormRDF (avec deux versions : en ligne et hors ligne) permettant de tester et de valider l'efficacité de notre approche.Afin de valider notre proposition, le prototype RDF2NormRDF a été utilisé avec une batterie de tests. Nos résultats expérimentaux ont montré des mesures très encourageantes par rapport aux approches existantes, notamment vis-à-vis du temps de chargement ou bien du stockage d'une description normalisée, tout en préservant le maximum d'informationsOver the past three decades, millions of people have been producing and sharing information on the Web, this information can be structured, semi-structured, and/or non-structured such as blogs, comments, Web pages, and multimedia data, etc., which require a formal description to help their publication and/or exchange on the Web. To help address this problem, the Word Wide Web Consortium (or W3C) introduced in 1999 the RDF standard as a data model designed to standardize the definition and use of metadata, in order to better describe and handle data semantics, thus improving interoperability, and scalability, and promoting the deployment of new Web applications. Currently, billions of RDF descriptions are available on the Web through the Linked Open Data cloud projects (e.g., DBpedia and LinkedGeoData). Also, several data providers have adopted the principles and practices of the Linked Data to share, connect, enrich and publish their information using the RDF standard, e.g., Governments (e.g., Canada Government), universities (e.g., Open University) and companies (e.g., BBC and CNN). As a result, both individuals and organizations are increasingly producing huge collections of RDF descriptions and exchanging them through different serialization formats (e.g., RDF/XML, Turtle, N-Triple, etc.). However, many available RDF descriptions (i.e., graphs and serializations) are noisy in terms of structure, syntax, and semantics, and thus may present problems when exploiting them (e.g., more storage, processing time, and loading time). In this study, we propose to clean RDF descriptions of redundancies and unused information, which we consider to be an essential and required stepping stone toward performing advanced RDF processing as well as the development of RDF databases and related applications (e.g., similarity computation, mapping, alignment, integration, versioning, clustering, and classification, etc.). For that purpose, we have defined a framework entitled R2NR which normalizes different RDF descriptions pertaining to the same information into one normalized representation, which can then be tuned both at the graph level and at the serialization level, depending on the target application and user requirements. We illustrate this approach by introducing use cases (real and synthetics) that need to be normalized.The contributions of the thesis can be summarized as follows:i. Producing a normalized (output) RDF representation that preserves all the information in the source (input) RDF descriptions,ii. Eliminating redundancies and disparities in the normalized RDF descriptions, both at the logical (graph) and physical (serialization) levels,iii. Computing a RDF serialization output adapted w.r.t. the target application requirements (faster loading, better storage, etc.),iv. Providing a mathematical formalization of the normalization process with dedicated normalization functions, operators, and rules with provable properties, andv. Providing a prototype tool called RDF2NormRDF (desktop and online versions) in order to test and to evaluate the approach's efficiency.In order to validate our framework, the prototype RDF2NormRDF has been tested through extensive experimentations. Experimental results are satisfactory show significant improvements over existing approaches, namely regarding loading time and file size, while preserving all the information from the original description
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Gordo, Bernardo Calado Mendes. "Equity reasearch - REN." Master's thesis, Instituto Superior de Economia e Gestão, 2017. http://hdl.handle.net/10400.5/14617.
Повний текст джерелаАнотація:
Mestrado em FinançasEsta dissertação tem como objetivo estimar o valor patrimonial da Redes Energéticas Nacionais (REN), bem como a estimação do valor intrínseco das ações da REN. É uma empresa de serviços públicos que se caracteriza por ser um operador de rede. A empresa está cotada no PSI 20 e opera nos seguintes segmentos de mercado: eletricidade, gás natural e telecomunicações (considerado como "outros" ao longo do relatório). A avaliação é elaborada considerando os diferentes segmentos onde a empresa opera e usando o modelo dos Fluxos de Caixa Descontados, mais especificamente o Adjusted Present Value (APV). Também elaborámos uma análise de sensibilidade e uma simulação Monte Carlo para avaliar a robustez dos resultados. Elaborámos igualmente uma Avaliação Relativa com o método dos Múltiplos. Os resultados foram de encontro à Análise dos Fluxos de Caixa Descontados. A nossa análise sugere que o valor das ações transacionadas da REN no dia 31.12.2016 estão subvalorizadas. Foram transacionadas a 2.68€ e o valor intrínseco é 2.99€, apresentando uma potencial variação positiva de 11.74%.
This dissertation aims to estimate the equity value of Redes Energéticas Nacionais (REN), as well as the intrinsic value of REN's share. REN is a utility company usually referred as transmission system operator or grid operator. The company is quoted in PSI 20 and operates in the following business segments: electricity, natural gas and telecommunication. The valuation is done considering the different segments where the company operates and using the Discount Cash Flow (DCF) model, more specifically the Adjusted Present Value (APV) model. We also perform a sensitivity analysis and a Monte Carlo simulation. To check the robustness of our results, we also perform a Relative Valuation with the Multiples approach. The results were according to the DCF analysis. Our analysis suggests that REN's shares at 31.12.2016 were undervalued. The trading value of the shares in that day was 2.68€, which is below the intrinsic value of 2.99€ as calculated by DCF analysis with APV method. The superior intrinsic value represents a 11.74% upside potential in relation to the trading value of the share of 2.68€.
info:eu-repo/semantics/publishedVersion
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Pöder, Sebastian. "Morse homology of RPn." Thesis, Uppsala universitet, Analys och tillämpad matematik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-202159.
Повний текст джерела
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Plotnick, Fredric Leigh Martin Joseph P. "RDM - relationship diagramming method /." Philadelphia, Pa. : Drexel University, 2008. http://hdl.handle.net/1860/2934.
Повний текст джерела
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Seth-Smith, Helena Margaret Brabazon. "Microbial degradation of RDX." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.619689.
Повний текст джерела
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Dongo, Escalante Irvin Franco Benito. "Anonymisation de documents RDF." Thesis, Pau, 2017. http://www.theses.fr/2017PAUU3045/document.
Повний текст джерелаАнотація:
Avec l'avancée du Web Sémantique et des initiatives Open Linked Data, une grande quantité de documents RDF sont disponibles sur Internet. L'objectif est de rendre ces données lisibles pour les humains et les machines, en adoptant des formats spéciaux et en les connectant à l'aide des IRIs (International Resource Identifier), qui sont des abstractions de ressources réelles du monde. L’augmentation du nombre de données publiées et partagées augmente également le nombre d’informations sensibles diffusées. En conséquence, la confidentialité des entités d'intérêts (personnes, entreprises, etc.) est un véritable défi, nécessitant des techniques spéciales pour assurer la confidentialité et la sécurité adéquate des données disponibles dans un environnement où chaque utilisateur a accès à l'information sans aucune restriction (Web).Ensuite, trois aspects principaux sont considérés pour assurer la protection de l'entité: (i) Préserver la confidentialité, en identifiant les données qui peuvent compromettre la confidentialité des entités (par exemple, les identifiants, les quasi-identifiants); (ii) Identifier l'utilité des données publiques pour diverses applications (par exemple, statistiques, tests, recherche); et (iii) Les connaissances antérieures du modèle qui peuvent être utilisées par les pirates informatiques (par exemple, le nombre de relations, une relation spécifique, l'information d'un nœud).L'anonymisation est une technique de protection de la confidentialité qui a été appliquée avec succès dans les bases de données et les graphes. Cependant, les études sur l'anonymisation dans le contexte des documents RDF sont très limitées. Ces études sont les travaux initiaux de protection des individus sur des documents RDF, puisqu'ils montrent les approches pratiques d'anonymisation pour des scénarios simples comme l'utilisation d'opérations de généralisation et d'opérations de suppression basées sur des hiérarchies. Cependant, pour des scénarios complexes, où une diversité de données est présentée, les approches d'anonymisations existantes n'assurent pas une confidentialité suffisante.Ainsi, dans ce contexte, nous proposons une approche d'anonymisation, qui analyse les voisins en fonction des connaissances antérieures, centrée sur la confidentialité des entités représentées comme des nœuds dans les documents RDF. Notre approche de l'anonymisation est capable de fournir une meilleure confidentialité, car elle prend en compte la condition de la diversité de l'environnement ainsi que les voisins (nœuds et arêtes) des entités d'intérêts. En outre, un processus d'anonymisation automatique est assuré par l'utilisation d'opérations d'anonymisations associées aux types de donnéesWith the advance of the Semantic Web and the Open Linked Data initiatives, a huge quantity of RDF data is available on Internet. The goal is to make this data readable for humans and machines, adopting special formats and connecting them by using International Resource Identifiers (IRIs), which are abstractions of real resources of the world. As more data is published and shared, sensitive information is also provided. In consequence, the privacy of entities of interest (e.g., people, companies) is a real challenge, requiring special techniques to ensure privacy and adequate security over data available in an environment in which every user has access to the information without any restriction (Web). Then, three main aspects are considered to ensure entity protection: (i) Preserve privacy, by identifying and treating the data that can compromise the privacy of the entities (e.g., identifiers, quasi-identifiers); (ii) Identify utility of the public data for diverse applications (e.g., statistics, testing, research); and (iii) Model background knowledge that can be used for adversaries (e.g., number of relationships, a specific relationship, information of a node). Anonymization is one technique for privacy protection that has been successfully applied in practice for databases and graph structures. However, studies about anonymization in the context of RDF data, are really limited. These studies are initial works for protecting individuals on RDF data, since they show a practical anonymization approach for simple scenarios as the use of generalization and suppression operations based on hierarchies. However, for complex scenarios, where a diversity of data is presented, the existing anonymization approaches does not ensure an enough privacy. Thus, in this context, we propose an anonymization framework, which analyzes the neighbors according to the background knowledge, focused on the privacy of entities represented as nodes in the RDF data. Our anonymization approach is able to provide better privacy, since it takes into account the l-diversity condition as well as the neighbors (nodes and edges) of entities of interest. Also, an automatic anonymization process is provided by the use of anonymization operations associated to the datatypes
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Fors, Josef, and Linda Larsson. "Ren hand - bara ibland." Thesis, Malmö högskola, Fakulteten för hälsa och samhälle (HS), 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-25466.
Повний текст джерелаАнотація:
Handhygien är den mest effektiva metoden för att motverka smittspridning och för att förebygga och begränsa förekomsten av vårdrelaterade infektioner. Att ”bara tvätta händerna” är dock inte tillräckligt för att åstadkomma ett adekvat skydd mot smittspridning. Handhygienen skall dessutom genomföras på ett korrekt sätt och vid rätt tillfälle i enlighet med föreskrivna riktlinjer. Syftet med denna litteraturstudie var att studera hur befintliga riktlinjer avseende handhygien i vårdarbete efterföljs av vårdpersonal i västvärlden. Den har huvudsakligen baserats på tio vetenskapliga artiklar som inbegriper studier, i vilka var och en på sitt sätt och i sitt specifika sammanhang, utvärderat följsamhet av riktlinjer för handhygien. Sammanställningen av resultaten visar att den generella följsamheten bland vårdpersonal i västvärlden är låg och sällan överstiger 50 %. Den visar också att följsamheten varierar mellan olika yrkeskategorier, där sjuksköterskor är den av de undersökta yrkesgrupper som överlag konstaterats stå för den högsta följsamheten. Handskanvändning verkar bidra till att vårdpersonal i högre grad tvättar sina händer efter patientkontakt och följsamheten ser generellt sett ut att vara högre efter patientkontakt jämfört med före. Av resultaten framkommer även att följsamheten tenderar att öka då handsprit finns att tillgå jämfört med när den inte finns att tillgå. Att handsprit görs mer lättillgänglig i samband med olika typer av handhygienprogram har också noterats medverka till en förbättrad följsamhet. Författarna till detta arbete vill, till följd av den uppenbara svårigheten med att praktisera en handhygien i enlighet med föreskrivna riktlinjer, vädja till alla vårdarbetare att ta detta problem på allvar och att var och en på sitt sätt och i möjligaste mån försöker bidra till en förbättring.Hand hygiene is the most effective method to prevent transmission of pathogens and to decrease the prevalence of nosocomial infections. However, ”just to wash the hands” is not a sufficient protection against pathogen transmission. In addition, hand hygiene must be carried out in a proper way and when it’s indicated according to published guidelines. The aim of this literature review was to study how health care workers adhere to hand hygiene guidelines in the Western World. Mainly, it’s based on ten scientific articles that comprise studies, in which each in its own way and specific context, having evaluated adherence to hand hygiene guidelines. The result compilation shows that the overall adherence among health care workers in the Western World is low and rarely exceeds 50 %. It also shows that adherence varies between different groups of health care workers, where nurses can be established as the most compliant group. Furthermore, the usage of gloves seems to contribute to a greater adherence to handwashing in situations after patient contact. Also, the general adherence appears to be higher in situations after patient contact compared to situations before patient contact. The results reveal that adherence tends to increase when hand rub solutions are present compared to when they not are present. The effort to make hand rub solutions more accessible through the implementation of hand hygiene programmes has also been proven to successfully contribute to better adherence rates. The authors of this work desire to, as a consequence of the obvious difficulty to perform hand hygiene according to published guidelines, appeal to all health care workers to consider this problem seriously and to make their own contributions to an overall improvement.
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Enberg, Maria, and Ronny Svensson. "Programmera på Ren Svenska." Thesis, Malmö högskola, Lärarutbildningen (LUT), 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-30977.
Повний текст джерелаАнотація:
IT-prototype for programming education in the form of a web-site. IT-prototype for programming education in the form of a web-site.Utveckling av prototyp till IT-läromedel i form av en hemsida för att underlätta inlärningen av programmering.
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Luk, Yu-ping. "Ren Bonian's Zhong Kui paintings." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B30568316.
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Wang, Xiaosheng. "Yu yan yu ren shi." Beijing : Zhongguo ren min da xue chu ban she, 1994.
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Luk, Yu-ping, and 陸於平. "Ren Bonian's Zhong Kui paintings." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B30568316.
Повний текст джерела
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Bah, Oury Amadou. "Database comparison, Oracle vs RDB." Virtual Press, 1992. http://liblink.bsu.edu/uhtbin/catkey/845945.
Повний текст джерелаАнотація:
Database and database technology are having a major impact on the growing use of computers. The rising popularity of database systems for the management of data has resulted in an increasing number of systems. As the number grows, the difficulty in choosing the system which will best meet the requirements of a particular application also increases. Knowing how to choose the correct one for a given application is important.The purpose of this thesis is to compare two very commonly used Database Management Systems (ORACLE and RDB) at Ball State University by describing and listing the advantages of each of them as well as their weaknesses, giving a comprehensive study of their performances, user friendliness, limits, and to aid users and managers in obtaining a deeper knowledge of these two systems.Department of Computer Science
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Alhaffar, Mohammed. "Database comparison : Oracle vs RDB." Virtual Press, 1992. http://liblink.bsu.edu/uhtbin/catkey/834505.
Повний текст джерелаАнотація:
Databases and database technology are having a major impact on the growing use of computers. It is fair to say that databases are playing a critical role in almost all areas where computers are used, including business, engineering, medicine, law, education, and library science, to name a few.At Ball State University, databases are very widely used among faculty, staff, and students. The common commercial database management system (DBMS) used in the university is ORACLE. Due to the extensive use of the system and the availability and easy access to alternative systems such as RDB/VMS, a comparative research is in order.This thesis is a comprehensive comparison between the two systems. It covers the differences in design, SQL codings, and the use of host programming language such as FORTRAN. It concentrates on the differences in memory usage, execution time, as well as the CPU time needed to precompile, link, and run.Department of Computer Science
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Bergner, Frank, Andreas Ulbricht, and Arne Wagner. "Langzeitspezifische Alterungseffekte in RDB-Stahl." Forschungszentrum Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-162216.
Повний текст джерелаАнотація:
Ziel des BMWi-Fördervorhabens 1501393 ist es, durch den Einsatz von Untersuchungsmethoden auf der nm-Skala einen Beitrag zur Aufklärung von Flusseffekten und von Late-Blooming-Effekten in bestrahlten RDB-Stählen zu leisten. Zur Untersuchung dieser Effekte wurde auf RDB-Stähle deutscher Reaktoren aus zwei bei der AREVA GmbH abgeschlossenen Vorhaben zurückgegriffen. Die Auswahl der Grundwerkstoffe und Schweißgüter erfolgte so, dass sich optimale Voraussetzungen für das Erreichen des Gesamtziels des Vorhabens ergeben. Die ausgewählten Untersuchungsmethoden umfassen mit der Neutronenkleinwinkelstreuung, der Atomsondentomographie und der Positronen-annihilationsspektroskopie solche Techniken, die die nm-skaligen bestrahlungsinduzierten Defekt-Fremdatom-Cluster bestmöglich und in komplementärer Weise zu detektieren und zu charakterisieren gestatten. Es wurde ein Flusseffekt auf die Größe der bestrahlungsinduzierten Fremdatomcluster, jedoch nicht auf den Volumenanteil und die mechanischen Eigenschaften gefunden. In einem Cu-armen RDB-Schweißgut wurde ein Late-Blooming-Effekt nachgewiesen, der sich in einem steilen Anstieg des Clustervolumenanteils und der Übergangstemperaturverschiebung nach einer Phase schwacher oder fehlender Zunahme niederschlägt.
The BMWi project 1501393 aimed at contributing to the clarification of flux effects and late blooming effects in irradiated RPV steels by means of experimental techniques of sensitivity at the nm scale. The investigation of these effects was focussed on RPV steels, both base metal and weld of German reactors selected according to the objectives of the present project from two previous projects performed at AREVA GmbH. The complementary techniques of small-angle neutron scattering, atom probe tomography and positron annihilation spectroscopy were applied to detect and characterize the irradiation-induced nm-scale defect-solute clusters. A flux effect on the size of the irradiation-induced clusters but no flux effect on both cluster volume fraction and mechanical properties was found. For a low-Cu RPV weld, a late blooming effect was observed, which results in a steep slope of both cluster volume fraction and transition temperature shift after an initial stage of small or no change.
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Arnvig, Kristine Bourke. "Transcription of rDNA in mycobacteria." Thesis, Open University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368021.
Повний текст джерела
28
Czerski, Helen. "Ignition of HMX and RDX." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442574.
Повний текст джерела
29
Schätzle, Alexander [Verfasser], and Georg [Akademischer Betreuer] Lausen. "Distributed RDF Querying on Hadoop." Freiburg : Universität, 2017. http://d-nb.info/1128574187/34.
Повний текст джерела
30
RODRIGUES, DANILO MORET. "DISTRIBUTED RDF GRAPH KEYWORD SEARCH." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2013. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=23832@1.
Повний текст джерелаАнотація:
PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIROCOORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR
PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTS. DE ENSINO
O objetivo desta dissertação é melhorar a busca por palavra-chave em formato RDF. Propomos uma abordagem escalável, baseada numa representação tensorial, que permite o armazenamento distribuído e, como consequência, o uso de técnicas de paralelismo para agilizar a busca sobre grandes bases de RDF, em particular, as publicadas como Linked Data. Um volume sem precedentes de informação está sendo disponibilizado seguindo os princípios de Linked Data, formando o que chamamos de Web of Data. Esta informação, tipicamente codificada como triplas RDF, costuma ser representada como um grafo, onde sujeitos e objetos são vértices, e predicados são arestas ligando os vértices. Em consequência da ampla adoção de mecanismos de busca na World Wide Web, usuários estão familiarizados com a busca por palavra-chave. No caso de grafos RDF, no entanto, a extração de uma partição coerente de grafos para enriquecer os resultados da busca é uma tarefa cara, demorada, e cuja expectativa do usuário é de que seja executada em tempo real. Este trabalho tem como objetivo o tratamento deste problema. Parte de uma solução proposta recentemente prega a indexação do grafo RDF como uma matriz esparsa, que contém um conjunto de informações pré-computadas para agilizar a extração de seções do grafo, e o uso de consultas baseadas em tensores sobre a matriz esparsa. Esta abordagem baseada em tensores permite que se tome vantagem de técnicas modernas de programação distribuída, e.g., a utilização de bases de dados não-relacionais fracionadas e o modelo de MapReduce. Nesta dissertação, propomos o desenho e exploramos a viabilidade da abordagem baseada em tensores, com o objetivo de construir um depósito de dados distribuído e agilizar a busca por palavras-chave com uma abordagem paralela.
The goal of this dissertation is to improve RDF keyword search. We propose a scalable approach, based on a tensor representation that allows for distributed storage, and thus the use of parallel techniques to speed up the search over large linked data sets, in particular those published as Linked Data. An unprecedented amount of information is becoming available following the principles of Linked Data, forming what is called the Web of Data. This information, typically codified as RDF subject-predicate-object triples, is commonly abstracted as a graph which subjects and objects are nodes, and predicates are edges connecting them. As a consequence of the widespread adoption of search engines on the World Wide Web, users are familiar with keyword search. For RDF graphs, however, extracting a coherent subset of data graphs to enrich search results is a time consuming and expensive task, and it is expected to be executed on-the-fly at user prompt. The dissertation s goal is to handle this problem. A recent proposal has been made to index RDF graphs as a sparse matrix with the pre-computed information necessary for faster retrieval of sub-graphs, and the use of tensor-based queries over the sparse matrix. The tensor approach can leverage modern distributed computing techniques, e.g., nonrelational database sharding and the MapReduce model. In this dissertation, we propose a design and explore the viability of the tensor-based approach to build a distributed datastore and speed up keyword search with a parallel approach.
31
Government, South African. "RDP white paper: discussion document." Government Printer, 1994. http://hdl.handle.net/10962/69419.
Повний текст джерелаАнотація:
My Government’s commitment to create a people-centred society of liberty binds us to the pursuit of the goals of freedom from want, freedom from hunger, freedom from deprivation, freedom from ignorance, freedom from suppression and freedom from fear. These freedoms are fundamental to the guarantee of human dignity. They will therefore constitute part of the centrepiece of what this Government will seek to achieve, the focal point on which our attention will be continuously focused. The things we have said constitute the true meaning, the justification and the purpose of the Reconstruction and Development Programme, without which it would lose all legitimacy.
32
Bergner, Frank, Andreas Ulbricht, and Arne Wagner. "Langzeitspezifische Alterungseffekte in RDB-Stahl." Helmholtz-Zentrum Dresden - Rossendorf, 2014. https://hzdr.qucosa.de/id/qucosa%3A22225.
Повний текст джерелаАнотація:
Ziel des BMWi-Fördervorhabens 1501393 ist es, durch den Einsatz von Untersuchungsmethoden auf der nm-Skala einen Beitrag zur Aufklärung von Flusseffekten und von Late-Blooming-Effekten in bestrahlten RDB-Stählen zu leisten. Zur Untersuchung dieser Effekte wurde auf RDB-Stähle deutscher Reaktoren aus zwei bei der AREVA GmbH abgeschlossenen Vorhaben zurückgegriffen. Die Auswahl der Grundwerkstoffe und Schweißgüter erfolgte so, dass sich optimale Voraussetzungen für das Erreichen des Gesamtziels des Vorhabens ergeben. Die ausgewählten Untersuchungsmethoden umfassen mit der Neutronenkleinwinkelstreuung, der Atomsondentomographie und der Positronen-annihilationsspektroskopie solche Techniken, die die nm-skaligen bestrahlungsinduzierten Defekt-Fremdatom-Cluster bestmöglich und in komplementärer Weise zu detektieren und zu charakterisieren gestatten. Es wurde ein Flusseffekt auf die Größe der bestrahlungsinduzierten Fremdatomcluster, jedoch nicht auf den Volumenanteil und die mechanischen Eigenschaften gefunden. In einem Cu-armen RDB-Schweißgut wurde ein Late-Blooming-Effekt nachgewiesen, der sich in einem steilen Anstieg des Clustervolumenanteils und der Übergangstemperaturverschiebung nach einer Phase schwacher oder fehlender Zunahme niederschlägt.
The BMWi project 1501393 aimed at contributing to the clarification of flux effects and late blooming effects in irradiated RPV steels by means of experimental techniques of sensitivity at the nm scale. The investigation of these effects was focussed on RPV steels, both base metal and weld of German reactors selected according to the objectives of the present project from two previous projects performed at AREVA GmbH. The complementary techniques of small-angle neutron scattering, atom probe tomography and positron annihilation spectroscopy were applied to detect and characterize the irradiation-induced nm-scale defect-solute clusters. A flux effect on the size of the irradiation-induced clusters but no flux effect on both cluster volume fraction and mechanical properties was found. For a low-Cu RPV weld, a late blooming effect was observed, which results in a steep slope of both cluster volume fraction and transition temperature shift after an initial stage of small or no change.
33
Loeuille, Damien. "Micro-imagerie RMN du cartilage." Nancy 1, 2002. http://www.theses.fr/2002NAN11307.
Повний текст джерела
34
Guillet, Éric. "Le roman picaresque en rda." Nantes, 1994. http://www.theses.fr/1994NANT3021.
Повний текст джерелаАнотація:
Le these poursuit trois objectifs principaux : 1) etre une reflexion sur le concept de picaresque dont elle propose la definition suivante : le roman picaresque, categorie esthetique universelle, exprime l'eternel retour de la contradiction entre l'etre, represente par le picaro qui tend fondamentalement a s'ouvrir, et le paraitre, represente par les personnages secondaires autour du picaro qui tendent fondamentalement a se fermer. 2) montrer la permanence dans le roman de rda des structures traditionnelles du roman picarresque qui subissent certes une metamorphose au cours de leur reactivation. 3) mettre en lumiere la civilisation d'un pays socialiste, la rda, ou le mode picaresque de representation litteraire de la realite reactivait une pensee reposant sur des principes (eternel retour du meme, pessimisme, refus de l'engagement) opposes a ceux prones par l'ideologie officielle (progres, optimisme, engagement)The thesis has three main aims : 1) to be a reflection on the concept of picaresque, a definition of which it propounds : the picaresque novel, a universal aesthetic category, expresses the eternal recurrence of contradiction between being, represented by the picaro who basically tends to open himself, and seeming, represented by the characters of minor importance around the picaro who basically tend to close themselves. 2) to show the permanence in the novel of the gdr of the traditional structures of the picaresque novel undergoing a change indeed during their restoration. 3) to throw a light on the culture of a socialist country, the gdr, where the picaresque way of depicting reality in literature restored a thought based upon principles (the eternal recurrence of the same, pessimism, the refusal of any involvement) contrary to the ones which the official ideology extolled (progress, optimism, commitment)
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Payen, de la Garanderie Philippe. "Les paratextes litteraires en rda." Nantes, 1997. http://www.theses.fr/1997NANT3012.
Повний текст джерелаАнотація:
L'etude de type "sociobibliologique" porte sur l'ecriture paratextuelle telle qu'elle fut pratiquee pendant plus de quarante ans en rda dans l'edition de la litterature universelle. Elle recense d'abord les differentes productions, a l'interieur du livre (et au-dela), par lesquelles l'editeur intervient dans le processus de mise en circulation sociale de l'oeuvre litteraire. Elle analyse ensuite les strategies discursives de la pre-ou postface est-allemande-ainsi que leurda, fuutions-afin d'en degager les principales fonctions (mobilisation, integration, assistance). Les paratextes, en r. . . . . . Ent les instruments indispensables d'une abondante edition litteraire. Ils traduisent une pratique pedagogique de la reception artistique, et illustrent, enfin les efforts entrepris en matiere de gestion de l'heritage culturelPrefaces played a major part in the publishing of literature in the german democratic republic. Along with other paratextual components, they represent the crossroads where the literary work assumes a social dimension. This "socialbibliological" study deals with the evolutions of the paratextual discourse, as it was developed for more than fourty years in the reception of world literature in the gdr
36
De, Paëpe Gaël. "Découplage hétéronucléaire en RMN solide." Lyon, École normale supérieure (sciences), 2004. http://www.theses.fr/2004ENSL0280.
Повний текст джерела
37
Nováková, Laura. "Nové možnosti v hojení ran." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2021. http://www.nusl.cz/ntk/nusl-449375.
Повний текст джерелаАнотація:
The diploma thesis is focused on the study of fibrous wound dressings prepared by electrospinning method from natural biopolymers. Three active ingredients were added to the dressings: ampicillin, ibuprofen and collagenase, which are responsible for relieving pain, reducing the risk of infection and selectively removing necrotic tissue in the wound. The theoretical part describes the therapeutic dressings currently available on the market and the most common methods of nanofiber production. The experimental part evaluates the optimization of the preparation of gelatin, alginate and chitosan fibrous wound dressings, which were subsequently enriched with active substances and their gradual release into the model environment was determined spectrophotometrically. Antimicrobial effects against E.coli and S. epidermidis strains andantifungal activity against C. glabrata yeast were monitored. Finally, two cytotoxicity tests on the human keratinocyte cell line HaCaT confirmed the safety of the prepared products, which can serve as bioactive skin dressings in the future.
38
Vedra, Lukáš. "Dekódování RDS zpráv obvodem FPGA." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2014. http://www.nusl.cz/ntk/nusl-220689.
Повний текст джерелаАнотація:
This thesis deals with demodulation, decoding RDS messages and an FM receiver in FPGA. It is the processing of data after A/D conversion of radio stereo signal. This work contains detailed theoretical knowledge of the RDS system, of the individual types of messages, their demodulation and subsequent decoding of individual services. There is theoretically analyzed in FPGA platform and implementation of RDS System and FM receiver.
39
Lachman, Jakub. "Roštový kotel na spalování RDF." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-401492.
Повний текст джерелаАнотація:
The master’s thesis deals with the design of a boiler for RDF combustion, based on the required power output and superheated steam parameters. The first part of the thesis focuses on combustion calculations. Boiler efficiency is also calculated in this chapter, using the heat balance efficiency method. The main part of the thesis consists of dimensional design and heat transfer calculations. The precision of the calculations is checked at the end of the thesis along with the chlorine corrosion, which is considered because of the higher amount of chlorine in the fuel. The thesis comes with a basic schematic of the designed boiler.
40
Dzurická, Lucia. "Příprava a charakterizace krytů ran." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2020. http://www.nusl.cz/ntk/nusl-414181.
Повний текст джерелаАнотація:
The diploma thesis if focused on the study of bioactive hydrogél and nanofiber wound dressings composed of natural biopolymers, which were functionalized by active compounds in the form of analgesic, antibiotics and enzymes. Hydrogél wound dressings were constituted from alginate and chitosan and nanofibers were created from polyhydroxybutyrate. The following 7 active compounds were selected to be added to the wound dressings: ampicillin, streptomycin, ibuprofen, papain, bromelain, collagenase and trypsin. In the theoretical part the structure of the skin and types of wound injuries were described. This part also talks about types of wound dressing and their applications, as well as treatment of skin wounds using enzymes and compounds with analgesic and antimicrobial properties. In addition, this section describes safety assays, in particular cytotoxicity assays on human cells. At the beginning of the experimental part, the process of preparation of hydrogél wound dressing was optimised. Subsequently, the dressings were enriched with active compounds and the rate of gradual releasing of the substances into model environment was monitored. In the case of enzymes, their proteolytic activity was also tested after their incorporation to the wound dressings. Furthermore, the prepared bioactive wound dressings were analyzed for possible cytotoxic effect on human keratinocytes. Finally, the wound dressing with combined content of active substances was created and also characterized for the rate of substance release, proteolytic activity and cytotoxicity. Antimicrobial activity of this wound dressings, against two selected strains of microorganisms: Escherichia coli and Staphylococcus epidermidis, was also evaluated.
41
Qiao, Shi. "QUERYING GRAPH STRUCTURED RDF DATA." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1447198654.
Повний текст джерела
42
Vaughan, Sebastian. "Peripherin/RDS : expression and characterisation." Thesis, University of Leeds, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485786.
Повний текст джерелаАнотація:
Peatlands are important terrestrial stores ofcarbon and a principal source ofdissolved organic carbon (DOC) to the fluvial environment.. Whilst often regarded as a net carbon sink, enhanced DOC concentrations and an associated rise in the level of water discolouration observed in many artificially drained peatland catchments across Europe and North America suggests that continued degradation may shift the balance of the carbon budget, such that they become a net carbon source. Peatland restoration, in the form of drain blocking, is currently being undertaken in a number of these locations. However, a great deal of this work 'has been carried out on a pragmatic or even an ad-hoc basis, with a distinct lack of process-based assessment. Thus, very little is known about how such changes in land management affect DOC and colour dynamics.. In order to bridge this knowledge gap, this thesis examines a range of processes known to influence DOC/colour production and release. A variety of field monitoring and laboratory measurements were undertaken to assess the upland blanket peat within the Oughtershaw Beck catchment in the Yorkshire Dales National Park, UK. The installation of drainage ditches was found to reduce both the carbon storage potential of the peat and the quality of upland catchment waters. Drainage lowered the depth ofthe water table across the peat by an average of 10 em, enhanced the rate of microbial activity by 33 % and increased DOC and colour production in soil water solutions by 35 %, 'relative to an adjacent intact site that had not been drained. The greater level of aeration in the upper peat layers associated with a lowered water table also appeared to reduce the degree of surface saturation and the occurrence ·of overland flow (OLF), resulting in a greater volume of water being drawn down into the peat body. The reduced saturation levels caused the subsidence and compaction of the upper soil layers, which increased the bulk density and ultimately reduced the degree of macroporosity within the soil. ill turn, this is thought to have increased the residence time and surface area over which percolating waters flow, which is likely to have enhanced the degree of interaction with decompositional products, and thus the mobility of DOC/colour.
43
Lindgren, Jonathan. "Melodifestivalen : Tur Eller Ren Skicklighet." Thesis, Uppsala universitet, Institutionen för musikvetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-279762.
Повний текст джерелаАнотація:
Denna uppsats handlar om relationen mellan startposition och topplaceringar. Syftet handlar om att analysera jurygruppernas poängfördelning, för att se om de har följt ett visst beteendemönster för att bestämma bidragens poäng i Melodifestivalen. Jag använder både kvantitativ studie och musikanalys i detta arbete. I den kvantitativa studien fokuserar jag främst på tabeller där tävlingarna hade 8, 10 och 12 bidrag i startfältet. Jag har gjort en uppdelning av Melodifestivalen, som består av den ”gamla” och den ”nya” Melodifestivalen. Den här uppdelningen går främst ut på hur röstningen har sett ut under Melodifestivalens alla år. Tävlingarna från 1959 till 1998, med undantag för 1962 och 1993, avgjordes med hjälp av juryrösterna. Och tävlingarna 1999 till idag avgjordes/avgörs med både jury- och telefonröster. Eftersom det är endast juryarbetet som ligger i fokus, exkluderades alla tävlingar som inte valde ut sina vinnare enbart med hjälp utav jurygrupper. Därmed utgår den kvantitativa studien från resultaten hos den ”gamla” Melodifestivalen. I den musikanalytiska delen av uppsatsen används Björn Skifs ”Det Blir Alltid Värre Framåt Natten” som forskningsobjekt, och sedan jämförs resultatet från analysen med de resterande bidragen i startfältet. Resultatet av denna uppsats visar att det finns bevis för att juryn har följt ett beteendemönster, men den visar också belägg för det motsatta. Sammanfattningsvis argumenterar jag i uppsatsen att det finns en möjlighet att jurygrupper har följt ett beteendemönster vid deras bedömande av bidrag.
44
Dekhil, Myriam. "RMN cristallographique : mesure de distances internucléaires sur des échantillons de poudre par RMN du solide." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM4734.
Повний текст джерелаАнотація:
La mesure de couplage dipolaire permet d’accéder à la structure tridimensionnelle d’un composé solide. Cependant, en présence d’une forte densité de spins couplés, le phénomène de troncature dipolaire rend difficile l’obtention de ces informations par RMN du solide. Ce problème peut être affranchi par l’étude de spins rares en abondance naturelle. En effet, avec une abondance naturelle de 1.1 %, la probabilité que trois 13C soient couplés, et avec elle la troncature dipolaire, devient négligeable. Une méthodologie basée sur la séquence de recouplage dipolaire POST-C7 permet d’accéder à des informations structurales d’échantillons en abondance naturelle sensibles à la fois à la conformation moléculaire et à l’empilement cristallin par mesure de couplages dipolaires 13C-13C. La sensibilité de détection des signaux RMN 13C est augmentée à l’aide la polarisation dynamique nucléaire ce qui permet de réduire considérablement les temps d’expériences. De plus, la séquence de recouplage R20_9_2 aidée de supercycles s’est montrée être plus robustes que POST-C7 face à de fortes anisotropies de déplacement chimique ou de forts couplages hétéronucléaires 1H-13C. La seconde problématique abordée concerne l’attribution de signaux 13C. En effet, il existe seulement quelques exemples de détermination de connectivités 13C -13C en abondance naturelle. Nous montrons ici que des spectres de corrélations dipolaires 13C-13C peuvent être obtenus en quelques jours à l’aide de la séquence de recouplage R20_9_2. Contrairement aux méthodologies basées sur le couplage J, notre séquence requiert un temps d’excitation DQ plus court ce qui la rend adaptée à l’étude de solides désordonnésMeasurment of dipolar coupling provides 3D structural information of powder samples. However, in practice, the high density of spins in organic compounds prevents the measurements of long-range dipolar couplings in solid-state NMR by the so-called dipolar truncation effect. The study of rare spins on natural abundance allows to overcome this problem. In fact, with a natural abundance of 1.1 %, the probability for three 13C to be coupled is negligible. We developed a methodology based either on the dipolar recoupling NMR pulse sequence POST-C7 or on the dramatic increase in sensitivity provided by dynamic nuclear polarization. We demonstrated that its methodology provides a measure of 13C-13C dipolar couplings in natural abundance powder samples and that the so-obtained distance information is sensitive to both molecular conformation and crystal packing of powder samples. Moreover, we show that the recoupling pulse sequence R20_9_2 is more robust to strong chemical shift anisotropy and also to strong 1H-13C heteronuclear dipolar couplings than POST-C7. The second challenge involves 13C signal assignment for natural abundance. In fact, there are only a few examples of 13C-13C correlation spectra obtained for natural abundance samples. Here, we show that 13C-13C correlation spectra sequence based on the reintroduction of 13C−13C dipolar couplings can be obtained with standard MAS probe and within few days using R20_9_2 pulse sequence. Contrary to pulse sequences based on 13C-13C J coupling, our pulse sequence requires shorter DQ excitation time and hence, is more suitable for samples having short T2 relaxation times such as amorphous solids
45
Sarfati, Muriel. "Développements et nouvelles applications de la spectroscopie RMN en milieu polypeptidique chiral : de la RMN du Sélénium à la RMN au Deutérium en abondance naturelle." Paris 11, 2004. http://www.theses.fr/2004PA112155.
Повний текст джерелаАнотація:
Le laboratoire de chimie structurale organique a developpe une technique de differenciation d'enantiomeres utilisant la rmn en solvant polypeptidique chiral. Dans la premiere partie de cette these, nous avons cherche a mettre en evidence le fort potentiel analytique de cette methodologie. Nous avons ainsi montre qu'elle fournit au chimiste diverses possibilites d'observer une differenciation chirale pour une molecule donnee ( rmn 1h, 2h ou 13c, utilisation de differents solvants orientes chiraux). Nous presentons par ailleurs le premier exemple de differenciation par rmn du selenium-77 en solvant oriente chiral. Dans une deuxieme partie, nous montrons que la rmn du deuterium en abondance naturelle en solvant cristal liquide chiral permet la discrimination chirale de molecules peu ou pas fonctionnalisees, les hydrocarbures chiraux, difficilement differenciables par les techniques de rmn classiquement utilisees. Dans une troisieme partie, nous nous sommes interesses au cas d'un hydrocarbure chiral particulier, la cis-decaline, dont les enantiomeres s'interconvertissent. Nous avons montre que la rmn du deuterium en solvant cristal liquide chiral permet la differenciation des enantiomeres de cette molecule a basse temperature (echange bloque) ainsi que de ses directions enantiotopes a haute temperature (echange rapide). Enfin, dans une derniere partie, nous proposons l'utilisation d'experiences bidimensionnelles de correlation homonucleaire deuterium-deuterium et heteronucleaire carbone-deuterium pour simplifier l'attribution des spectres du deuterium et la mesure des eclatements quadripolaires de molecules perdeuteriees chirales en solvant cristal liquide chiralSince several years, the laboratoire de chimie structurale organique (university paris-sud) is developing new analytical techniques to discriminate enantiomers using nmr spectroscopy in weakly orienting chiral liquid crystals (clc). In the first part of this thesis, we aim to demonstrate the strong potential of this original methodology using organic solutions of polypeptide (pblg, pcbll) as oriented media. We show that this approach provides to (bio)chemists various possibilities to observe enantiomers of any given organic chiral molecule (1h, 2h or 13c nmr at natural abundance level, use of various clc,). In addition, we present the first example of spectral enantiodiscrimination using selenium-77 nmr spectroscopy in a clc. In a second part, we show that natural abundance deuterium nmr spectroscopy is a very powerful tool, able to discriminate between enantiomers of a wide range of rigid and flexible chiral hydrocarbons. Thus we propose an efficient alternative to classical nmr techniques that generally fail to analyse unfonctionalized chiral compounds. In a third part, we focus our attention on a particular chiral bicycloalkane, the cis-decalin, which shows an interesting conformational dynamic. Thus we show that deuterium nmr in polypeptide oriented phases permits the discrimination of its enantiomers at low temperature (slow exchange) as well as its enantiotopic directions at high temperature (rapid exchange). In the last part, we describe the use of homonuclear (2h-2h) and heteronuclear (13c-2h) correlation 2d nmr experiments to simplify the assignment of deuterium spectra and the measurement of quadripolar splittings of deuterated chiral molecules
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Avuglah, Bright Kwaku. "Developing an implementation plan for research data management (RDM) at the University of Ghana." Diss., University of Pretoria, 2016. http://hdl.handle.net/2263/62100.
Повний текст джерелаАнотація:
The current global and data intensive outlook of research provides new opportunities and challenges for HEIs including effective and sustainable RDM. As a growing area of interest in the global research arena, experiences from developed countries have dominated the body of literature on RDM. This study is in part, to fill this gap by assessing the state of the art of RDM and institutional preparedness at the University of Ghana (through existing data management activities and capabilities) in order to develop a plan for implementation.
The study used a qualitative case study method and gathered data using semi-structured interviews and document analysis. Thematic analysis method was used to analyse the data collected. A total of seven respondents (five service providers and two senior researchers) were selected purposively using two sampling techniques ("priori criteria sampling" and snowball sampling). Criteria were set for their inclusion and each respondent provided information about institutional support, capabilities, policies and expectations on RDM.
The findings of the study revealed a number of RDM related activities, these include support for collaborative research, support for data analysis and computational science, guidance on RDM and grant applications as well as support for storage and high-speed connectivity to facility the research enterprise at UG. In terms of capabilities, no specific RDM policy was identified, existing infrastructure identified include an HPC cluster, a private cloud facility (HP Cloud Matrix), an Institutional repository (UGSpace), an institutional Google Drive platform, data analysis packages (NVivo and SPSS) and a robust network and security infrastructure. These were not necessarily provisioned for RDM purposes. Also, the findings show that staff do not possess the necessary skills or adequate knowledge to fully support RDM at UG.
In terms of the specific objectives of the study, the results of the semi-structured interviews and document analysis provided an understanding of the current situation (i.e. requirements, current activities and capabilities at the UG) which is the first objective of the study. These findings were then benchmarked against the EPSRC policy framework following the outline of the DCC CARDIO Matrix and using the optimal desirable expectation or level of development as the standard for comparison. This was useful in identifying gaps in RDM awareness, support and capabilities at UG which is the second objective of the study. To achieve the third objective, which was identifying priority areas for RDM development, the researcher examined both initial findings (i.e. findings on requirements, current activities and capabilities identified under the first objective as well as the gaps identified in the second objective) and proposed six broad areas where UG must focus its RDM development agenda. Finally, the six broad areas proposed in objective three were further cascaded into a number of specific initiatives and tasks to be implemented. This was done taking cognisance of the potential of current infrastructure, gaps identified in institutional awareness and capabilities as well as essentials for a cultural changed. The study concluded that RDM at the University of Ghana is currently underdeveloped but with immense potential for growth. While a few RDM related activities were identified, existing capabilities were generally found to be inchoate, uncoordinated and not formally instituted.
The study recommended six main areas where the UG should focus RDM development, these include: constituting a steering group to spearhead and coordinate RDM development at the UG, developing a coordinated policy framework for RDM at UG, streamlining existing technical infrastructure to support data management requirements, creating opportunities for RDM training and capacity development for professional staff, researchers and students, developing services to support requirements, and exploring internal funding strategies to facilitate RDM development and support at the UG. The study also recommends that the academic community at the UG should be actively engaged throughout the RDM development process as this is critical to ensure that the eventual solutions are fit for purpose and acceptable.Mini Dissertation (MIT)--University of Pretoria, 2016.
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Bary, Nicole. "L'image de la RDA en France: Réception et traduction de la littérature de RDA en France." Universität Leipzig, 1999. https://ul.qucosa.de/id/qucosa%3A33364.
Повний текст джерела
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Veitshans, Thomas. "Propriétés des réseaux permanents ou temporaires dans les polymères : gonflement ; RMN et simulation ; RMN et écoulement." Université Joseph Fourier (Grenoble), 1998. http://www.theses.fr/1998GRE10206.
Повний текст джерелаАнотація:
Sont presentes trois projets permettant de mieux comprendre la structure de systemes polymeres et les liens entre cette structure et les grandeurs de l'approche rmn. Dans la partie etude de gels bimodaux nous mettons en evidence une relation entre des parametres rmn et des moments de la distribution de la longueur des chaines entre deux nuds. Nous developpons en outre une version bimodale du theoreme c#* que nous verifions. Le deuxieme projet est intitule simulation de la relaxation de l'aimantation transversale d'une chaine gaussienne en solution diluee, fixee aux extremites. Nous creons un code de calcul adapte a cette premiere etude numerique dans le domaine de l'approche rmn aux systemes polymeres. Le potentiel de telles etudes est montre par une analyse de la relaxation de l'aimantation transversale m#x(t). La partie relaxation de l'aimantation transversale d'un fluide de polymeres enchevetres et soumis a un cisaillement concerne l'etude du reseau temporaire des enchevetrements. Nous presentons un dispositif original permettant d'observer par rmn des fluides cisailles. Nous avons observe qu'un cisaillement n'a pas d'influence sur la fonction m#x(t) d'une solution semi-diluee dans la gamme des taux de cisaillement etudies. Cette etude necessite d'etre completee par des etudes subsequentes que nous specifions. Par ailleurs, d'autres etudes consecutives aux trois projets de recherche sont proposees. En particulier, nous decrivons une etude qui mettrait en evidence l'objectif commun des trois projets : mieux comprendre la physique de systemes polymeres et cela grace aux moyens que nous donne l'approche rmn.
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Schulenburg, Sven. "Analyse der RDF-Produktion in Vietnam." Master's thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-38577.
Повний текст джерелаАнотація:
A simplified RDF production was made, together with a waste characterization of MSW from Hanoi area. Three experiments were done, two with active aeration and one without. A high water content was determined at all RDF, which has a negative influence on the lower heating value and a saving-effect. A accumulation of the heating value to the higher class (>40mm), was not completely possible, also no complete transfer of mineral contents to the lower class (<10mm). The RDF reach in most cases the criteria for a fuel for different limit values, heavy metals, chloride and sulfur. An economic benefit could be possible with a surplus income by using RDF instead of coal (lignite), also by avoiding landfill gas and sell emission rights via CDM. More and detailed investigations seem to be necessary to confirm these results.
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Ron, Eyal [Verfasser]. "Hysteresis-Delay Differential Equations / Eyal Ron." Berlin : Freie Universität Berlin, 2016. http://d-nb.info/1121588026/34.
Повний текст джерела