Статті в журналах: "Radiation theray"

1

Kim, Sung-Kyu. "Quality Assurance in Intensity Modulated Radiation Theray." Yeungnam University Journal of Medicine 25, no. 2 (2008): 85. http://dx.doi.org/10.12701/yujm.2008.25.2.85.

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2

Muñoz-Neira, Milton, Jorge Cruz-Duarte, and Rodrigo Correa. "Calentamiento simultáneo microondas-radiación térmica." Revista UIS Ingenierías 19, no. 2 (March 5, 2020): 33–41. http://dx.doi.org/10.18273/revuin.v19n2-2020004.

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En este artículo se presentan resultados de la simulación del tratamiento térmico híbrido de materiales, utilizando ondas electromagnéticas en el rango de las microondas y el calor por radiación térmica generado por una resistencia eléctrica. La resistencia se ubicó de tal forma que solo la mitad del sólido (una esfera de dos capas) recibela energía generada por ésta. Además, la resistenciase controló de tal forma que generó energía térmicadeforma uniforme y constante. Igualmente,se definieronmateriales con propiedades termofísicas diferentes en cada capa, pero invariantes tantocon la posicióncomo con la temperatura. El flujo de calor volumétrico se consideró constante con el tiempo. Los perfiles de temperatura para cada capa mostraron variaciones en el tiempo y la posición, observándose que elcalentamiento simultáneo facilita lamanipulación de estos perfiles, de acuerdo con las necesidades del tratamiento térmico. Así, se evidenció la ventaja de éste tipo decalentamiento híbrido.

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3

Reddya, U. Umamaheswara, and Panduranganath . "Comparison of Volumetric Modulated ARC Therapy (VMAT) to Conventional Intensity Modulated Radiation Therapy for Carcinoma Cervix." Indian Journal of Cancer Education and Research 5, no. 2 (2017): 113–25. http://dx.doi.org/10.21088/ijcer.2321.9815.5217.10.

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4

Surzhikov, A. P. "PHASE TRANSFORMATIONS IN FERRITES DURING RADIATION-THERMAL SINTERING." Eurasian Physical Technical Journal 17, no. 1 (June 2020): 26–34. http://dx.doi.org/10.31489/2020no1/26-34.

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5

Cruz, Marli. "Stroke-Like Migraine Attacks After Radiation Therapy (SMART): Um Caso Clínico." Medicina Interna 26, no. 4 (December 11, 2019): 308–11. http://dx.doi.org/10.24950/rspmi/cc/20/19/4/2019.

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6

Rebeca, Steve. "Metastatic Brain Tumors: Current Therapeutic Options through Surgery and Radiation Therapy." Neuroscience and Neurological Surgery 1, no. 2 (March 20, 2017): 01–03. http://dx.doi.org/10.31579/2578-8868/055.

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7

Chiang, Ren-Tai. "Analysis of Radiation Interactions and Biological Effects for Boron Neutron Capture Therapy." ASEAN Journal on Science and Technology for Development 35, no. 3 (December 24, 2018): 203–7. http://dx.doi.org/10.29037/ajstd.535.

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The direct and indirect ionizing radiation sources for boron neutron capture therapy (BNCT)are identi?ed. The mechanisms of physical, chemical and biological radiation interactions for BNCT are systematically described and analyzed. The relationship between the effect of biological radiation and radiation dose are illustrated and analyzed for BNCT. If the DNAs in chromosomes are damaged by ion- izing radiations, the instructions that control the cell function and reproduction are also damaged. This radiation damage may be reparable, irreparable, or incorrectly repaired. The irreparable damage can result in cell death at next mitosis while incorrectly repaired damage can result in mutation. Cell death leads to variable degrees of tissue dysfunction, which can affect the whole organism’s functions. Can- cer cells cannot live without oxygen and nutrients via the blood supply. A cancer tumor can be shrunk by damaging angiogenic factors and/or capillaries via ionizing radiations to decrease blood supply into the cancer tumor. The collisions between ionizing radiations and the target nuclei and the absorption of the ultraviolet, visible light, infrared and microwaves from bremsstrahlung in the tumor can heat up and damage cancer cells and function as thermotherapy. The cancer cells are more chemically and biologically sensitive at the BNCT-induced higher temperatures since free-radical-induced chemical re- actions are more random and vigorous at higher temperatures after irradiation, and consequently the cancer cells are harder to divide or even survive due to more cell DNA damage. BNCT is demonstrated via a recent clinical trial that it is quite effective in treating recurrent nasopharyngeal cancer.

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8

Malyshev A.V., A. V. "RELATIONSHIP BETWEEN MAGNETIC PROPERTIES AND MICROSTRUCTURE OF FERRITES DURING SINTERING IN RADIATION AND RADIATION-THERMAL CONDITIONS." Eurasian Physical Technical Journal 18, no. 1 (March 30, 2021): 3–8. http://dx.doi.org/10.31489/2021no1/3-8.

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The studies of correlation between magnetic properties and microstructure were conducted on samples of lithium-substituted ferrite, sintered in radiation and radiation-thermal conditions. Radiation-thermal sintering was performed for compacts irradiated with a pulsed electron beam with energy of (1.5–2.0) MeV, beam current per pulse of (0.5-0.9) A, irradiation pulse duration of 500 μs, pulse repetition rate of (5–50) Hz, and compact heating rate of 1000 C/min. Sintering in thermal furnaces (T-sintering) was carried out in a preheated chamber electric furnace. The paper shows that magnetic induction does not depend on the ferrite grain size. In this case, the coercive force is inversely proportional to the grain size and depends on the intragranular porosity of ferrite samples. In contrast to thermal sintering, radiation-thermal sintering does not cause capturing of intergranular voids by growing grains and enhances coagulation of intragranular pores.

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9

Castela, A. S., A. M. Simões, G. Davies, and M. G. S. Ferreira. "Weathering of coil-coatings: UV radiation and thermal effects." Revista de Metalurgia 39, Extra (December 17, 2003): 167–73. http://dx.doi.org/10.3989/revmetalm.2003.v39.iextra.1115.

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10

Oyelami, Funmilayo H., Ebenezer O. Ige, Bidemi O. Falodun, Olaide Y. Saka-Balogun, and Oluwaseyi A. Adeyemo. "Magneto-Hemodynamics Fluid Hyperthermia in a Tumor with Blood Perfusion." Mathematical Modelling of Engineering Problems 9, no. 5 (December 13, 2022): 1210–16. http://dx.doi.org/10.18280/mmep.090507.

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In order to increase the drug potency and cancer treatment effectiveness, hyperthermia therapy is an adjuvant procedure in which perfused bodily tissues are heated to extreme temperatures. While certain types of hyperthermia treatments rely on thermal radiations from single-sourced electro-radiation measures, conjugating dual radiation field sources is being discussed in an effort to enhance the delivery of therapy. The thermal efficiency of a combined infrared hyperemia with nanoparticle recirculation near an applied magnetic field on subcutaneous strata of a model lesion as an ablation technique is investigated computationally in this research. To tackle the equation of linked momentum and thermal equilibrium in the blood-perfused tissue domain of a spongy fibrous tissue, an intricate Spectral relaxation method (SRM) was developed. The well-known Roseland diffusion approximation was used to define thermal diffusion regimes in the presence of external magnetic field imposition and to outline the effects of radiative flux inside the computational domain. Utilizing pore-scale porosity mechanics, the contribution of tissue sponginess was studied in a number of clinically relevant circumstances. Our findings demonstrated that magnetic field architecture could govern hemodynamic regimes at the blood-tissue interface across a significant depth of spongy lesion while permitting thermal transport across the depth of the model lesion. This parameter-indicator could be used to regulate how much hyperthermia therapy is administered to intravenously perfused tissue.

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11

Meyer, Christian P., Christer Groeben, Phillip Marks, Rainer Koch, and Johannes Huber. "Trends of Metastasis-Directed Treatments in Patients with Renal Cell Carcinoma: A Total Population-Based Analysis in Germany in the Era of Targeted Therapies." Oncology Research and Treatment 43, no. 12 (2020): 679–85. http://dx.doi.org/10.1159/000511753.

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Introduction: We characterize trends of metastasis-directed treatments in patients with metastatic renal cell carcinoma (mRCC) in Germany in the targeted therapy era. Methods: We identified all cases with a diagnosis of renal cell carcinoma (ICD-10: C.64) and site-specific codes for secondary malignant neoplasms (C79.x) in combination with procedural codes for resection and radiation from the Institute of Hospital Remuneration and the German Federal Statistical Office (Destatis) between 2006 and 2014. We assessed site-specific temporal trends using estimated annual percent change (EAPC) linear regression. Results: Overall, 15,742 resections and 21,224 radiation treatments were recorded. These targeted lung (44.1% resections; 22.0% radiations), lymph node (14.0% resections; 12% radiations), bone (21% resections; 38% radiations), liver (9% resections; 7% radiations), adrenal (11% resections; 3% radiations), and CNS metastases (2% resections; 19% radiations). There was a significantly increasing trend for resection of lung (EAPC +1.33, p = 0.011), bone (EAPC +2.48, p = 0.014), and adrenal (EAPC +3.4, p = 0.003) metastases, while trends for resection of CNS metastases significantly decreased (EAPC –7.93, p = 0.005). Between Western and Eastern Germany linear trends of resection (EAPC +2.75, p < 0.001; EAPC –0.44, p = 0.54) and radiation (EAPC +1.08, p = 0.15; –3.41, p = 0.03) differed significantly. Conclusion: We observed an increasing trend for metastasis-directed resections and slightly declining numbers for radiation therapy in Germany for mRCC in the targeted therapy era. Treatment differed by geography. These findings suggest more aggressive treatment algorithms following the availability of targeted therapies and a yet diverging treatment landscape needing further exploration.

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12

RADES, DIRK, LIESA DZIGGEL, THEO VENINGA, AMIRA BAJROVIC, and STEVEN E. SCHILD. "Overall Survival After Whole-Brain Radiation Therapy for Intracerebral Metastases from Testicular Cancer." Anticancer Research 36, no. 9 (September 9, 2016): 4817–20. http://dx.doi.org/10.21873/anticanres.11042.

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13

Tanaka, Osamu, Masahide Hayashi, Shinya Hayashi, and Iida Takayoshi. "Analiza zastosowania radioterapii w leczeniu nowotworów kobiecych z przerzutami do węzłów chłonnych nadobojczykowych." Current Gynecologic Oncology 14, no. 2 (July 29, 2016): 85–88. http://dx.doi.org/10.15557/cgo.2016.0009.

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14

Lodhi, Anand. "Functioning of Radiation Therapy During COVID-19 Pandemic in Red Zone COVID Hospital." Indian Journal of Cancer Education and Research 8, no. 1 (June 1, 2020): 35–38. http://dx.doi.org/10.21088/ijcer.2321.9815.8120.5.

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15

Stary, O. "FORMATION OF MAGNETIC PROPERTIES OF FERRITES DURING RADIATION-THERMAL SINTERING." Eurasian Physical Technical Journal 17, no. 2 (December 24, 2020): 6–10. http://dx.doi.org/10.31489/2020no2/6-10.

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The results of a comparative analysis of the laws governing the formation of ferrite hysteresis loop parameters sintered in thermal and radiation-thermal conditions were shown. The influence of radiation exposure on the interconversion of microstructure defects and their content in ferrites, depending on the duration and temperature of treatment, was established. Also, it was shown that recrystallization grain growth under irradiation conditions is ahead of grain growth during thermal heating. The observed radiation effects were associated with the effect of radiation on the microstructure. The magnetic parameters are uniquely determined by the compaction of the sample.

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16

Lv Xiangyin, 吕相银, 陈宗胜 Chen Zongsheng, 李志刚 Li Zhigang та 时家明 Shi Jiaming. "环境辐射对热像仪测温的影响". Infrared and Laser Engineering 51, № 3 (2022): 20210159. http://dx.doi.org/10.3788/irla20210159.

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17

Tasaki, Yutaro, Kazuto Ashizawa, Daisuke Nakamura, and Takashi Mizowaki. "Radiation pneumonitis after repeat stereotactic body radiation therapy for early-stage non-small cell lung cancer: A case series of two patients." Journal of Case Reports and Images in Oncology 8, no. 2 (January 6, 2023): 10–14. http://dx.doi.org/10.5348/100109z10yt2022cs.

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Introduction: Stereotactic body radiation therapy (SBRT) is a well-established treatment option for patients with early-stage non-small cell lung cancer (NSCLC). We retrospectively identified 82 patients with early-stage NSCLC treated with SBRT at our institution between November 2009 and September 2019. Among these patients, two developed local recurrence or new primary lung cancer and lung metastasis or new primary lung cancer, respectively, and were treated with repeat SBRT. We herein report a case series of two patients with radiation pneumonitis after repeat SBRT. Case Series: Case A was an 80-year-old woman diagnosed with stage I (T1aN0M0) squamous cell carcinoma. She received initial SBRT at an irradiation dose of 48 Gy in 4 fractions at the isocenter. Two years and three months after initial SBRT, the patient was clinically diagnosed with post-SBRT local recurrence or primary lung cancer and, thus, was treated with repeat SBRT at an irradiation dose of 60 Gy in 10 fractions. Six months later, the patient developed grade 5 radiation pneumonitis. Case B was an 89-year-old man diagnosed with stage I (T1cN0M0) adenocarcinoma. He received initial SBRT at an irradiation dose of 48 Gy in 4 fractions at the isocenter. Three years and six months after initial SBRT, the patient was clinically diagnosed with post-SBRT lung metastasis or primary lung cancer and, thus, was treated with repeat SBRT at an irradiation dose of 50 Gy in 4 fractions. Six months later, the patient developed grade 3 radiation pneumonitis. Conclusion: Caution is needed when performing repeat SBRT.

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18

Dempsey, Shane E., Naomi Findlay, and Lesley MacDonald-Wicks. "Increasing nutritional support for patients undergoing radiation therapy: the radiation therapist perspective." Journal of Radiotherapy in Practice 10, no. 3 (November 26, 2010): 181–89. http://dx.doi.org/10.1017/s1460396910000257.

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AbstractPurpose: The aim of this study was to determine radiation therapists’ knowledge on the nutritional management of side effects for patients receiving treatment to the gastrointestinal tract and genitourinary system and to determine the willingness of radiation therapists’ to participate in nutritional training.Method: A cross-sectional survey at a Radiation Oncology Treatment Centre was performed coupled with a semi-structured interview to explore radiation therapists’ knowledge and experiences related to patient nutritional care.Results: Eighty-one percent of participants agreed that they were often asked by patients for advice on eating. The majority of participants recognised that providing adequate nutrition support would be beneficial in terms of patient outcomes (91%) and ongoing patient compliance with nutrition advice (81%). However, participants demonstrated low confidence in providing nutrition support. Eighty-six percent of radiation therapists had not received any training on nutritional interventions and 100% of radiation therapists were interested in receiving more training.Conclusion: This research indicates that radiations therapists are often asked for nutritional advice by patients and recognise the associated benefits but are not confident in providing advice. Our findings reveal an opportunity for radiation therapists to provide scripted nutrition advice to patients to reinforce recommendations made by dietitian.

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19

Ige, Ebenezer O., Funmilayo H. Oyelami, Joshua Olutayo-Irheren, and Joseph T. Okunlola. "Magneto-Hemodynamic of Blood Flow Having Impact of Radiative Flux Due to Infrared Magnetic Hyperthermia: Spectral Relaxation Approach." International Journal of Design & Nature and Ecodynamics 17, no. 5 (October 31, 2022): 773–79. http://dx.doi.org/10.18280/ijdne.170516.

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Hyperthermia therapy is an adjuvant procedure during which perfused body tissues is subjected to elevated range of temperature in bid to achieve improved drug potency and efficacy of cancer treatment. While a selected class of hyperthermia techniques is shouldered on the thermal radiations derived from single-sourced electro-radiation measures, there are deliberations on conjugating dual radiation field sources in an attempt to improve the delivery of therapy procedure. This paper numerically explores the thermal effectiveness of combined infrared hyperemia having nanoparticle recirculation in the vicinity of imposed magnetic field on subcutaneous strata of a model lesion as ablation scheme. An elaborate Spectral relaxation method (SRM) was formulated to handle equation of coupled momentum and thermal equilibrium in the blood-perfused tissue domain of a spongy fibrous tissue. Thermal diffusion regimes in the presence of external magnetic field imposition were described leveraging on the renowned Roseland diffusion approximation to delineate the impact of radiative flux within the computational domain. The contribution of tissue sponginess was examined using mechanics of pore-scale porosity over a selected of clinical informed scenarios. Our observations showed for a substantial depth of spongy lesion, magnetic field architecture constitute the control regimes of hemodynamics in the blood-tissue interface while facilitating thermal transport across the depth of the model lesion. This parameter-indicator could be utilized to control the dispensing of hyperthermia treatment in intravenous perfused tissue.

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20

Malyshev, A. V. "CORRECTIONto the article«RELATIONSHIP BETWEEN MAGNETIC PROPERTIES AND MICROSTRUCTURE OF FERRITES DURING SINTERING IN RADIATION AND RADIATION-THERMAL CONDITIONS»." Eurasian Physical Technical Journal 19, no. 42 (December 20, 2022): 88. http://dx.doi.org/10.31489/2022no4/88.

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TheOriginal Article(https://phtj.buketov.edu.kz/index.php/EPTJ/article/view/78)was published on 2021-03-01Eurasian Physical Technical Journal, 2021, Vol.18, No.1 (35), pp. 3 –8.https://doi.org/10.31489/2021No1/3-8

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21

Scott, Bobby R., and Jennifer Di Palma. "Sparsely Ionizing Diagnostic and Natural Background Radiations are Likely Preventing Cancer and other Genomic-Instability-Associated Diseases." Dose-Response 5, no. 3 (July 1, 2007): dose—response.0. http://dx.doi.org/10.2203/dose-response.06-002.scott.

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Routine diagnostic X-rays (e.g., chest X-rays, mammograms, computed tomography scans) and routine diagnostic nuclear medicine procedures using sparsely ionizing radiation forms (e.g., beta and gamma radiations) stimulate the removal of precancerous neoplastically transformed and other genomically unstable cells from the body (medical radiation hormesis). The indicated radiation hormesis arises because radiation doses above an individual-specific stochastic threshold activate a system of cooperative protective processes that include high-fidelity DNA repair/apoptosis (presumed p53 related), an auxiliary apoptosis process (PAM process) that is presumed p53-independent, and stimulated immunity. These forms of induced protection are called adapted protection because they are associated with the radiation adaptive response. Diagnostic X-ray sources, other sources of sparsely ionizing radiation used in nuclear medicine diagnostic procedures, as well as radioisotope-labeled immunoglobulins could be used in conjunction with apoptosis-sensitizing agents (e.g., the natural phenolic compound resveratrol) in curing existing cancer via low-dose fractionated or low-dose, low-dose-rate therapy (therapeutic radiation hormesis). Evidence is provided to support the existence of both therapeutic (curing existing cancer) and medical (cancer prevention) radiation hormesis. Evidence is also provided demonstrating that exposure to environmental sparsely ionizing radiations, such as gamma rays, protect from cancer occurrence and the occurrence of other diseases via inducing adapted protection (environmental radiation hormesis).

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22

Moningi, Shalini, Elwood P. Armour, Stephanie A. Terezakis, Jonathan E. Efron, Susan L. Gearhart, Trinity J. Bivalacqua, Yi Le, et al. "High-dose-rate intraoperative radiation therapy: the nuts and bolts of starting a program." Journal of Contemporary Brachytherapy 1 (2014): 99–105. http://dx.doi.org/10.5114/jcb.2014.42027.

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23

Surzhikov, A. P. "ELECTROMIGRATION IN LITHIUM-TITANIUM FERRITE CERAMICS SINTERED IN RADIATION-THERMAL MODE." Eurasian Physical Technical Journal 18, no. 2 (June 11, 2021): 18–22. http://dx.doi.org/10.31489/2021no2/18-22.

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The study investigates electro-migration in Li–Ti ferrite ceramic samples sintered in radiation-thermal mode. To reveal radiation effects, similar measurements are performed for samples sintered in thermal mode. The effect of the state of grain boundaries and the presence of a low-melting additive on electrical properties of sintered ferrites is studied. It is found that structural rearrangement during radiation-thermal sintering occurs in early sintering stages, including the heating period. Study demonstrates that such behavior associated with radiation-induced intensification of the liquid phase spreading over the array of powder grains. In addition, it was shown that structural transformation may be caused by stimulation of intergranular slippage

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24

Yang Zhiyong, 杨志勇, 陆高翔 Lu Gaoxiang, 张志伟 Zhang Zhiwei та 宋俊辰 Song Junchen. "热辐射环境下目标红外偏振特性分析". Acta Optica Sinica 42, № 2 (2022): 0220001. http://dx.doi.org/10.3788/aos202242.0220001.

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25

Ali, Suha Ismail Ahmed, and Éva Lublóy. "Radiation shielding structures : Concepts, behaviour and the role of the heavy weight concrete as a shielding material - Rewiev." Concrete Structures 21 (2020): 24–30. http://dx.doi.org/10.32970/cs.2020.1.4.

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The construction of radiation shielding buildings still developed. Application of ionizing radiations became necessary for different reasons, like electricity generation, industry, medical (therapy treatment), agriculture, and scientific research. Different countries all over the world moving toward energy saving, besides growing the demand for using radiation in several aspects. Nuclear power plants, healthcare buildings, industrial buildings, and aerospace are the main neutrons and gamma shielding buildings. Special design and building materials are required to enhance safety and reduce the risk of radiation emission. Radiation shielding, strength, fire resistance, and durability are the most important properties, cost-effective and environmentally friendly are coming next. Heavy-weight concrete (HWC) is used widely in neutron shielding materials due to its cost-effectiveness and worthy physical and mechanical properties. This paper aims to give an overview of nuclear buildings, their application, and behaviour under different radiations. Also to review the heavy-weight concrete and heavy aggregate and their important role in developing the neutrons shielding materials. Conclusions showed there are still some gaps in improving the heavy-weight concrete (HWC) properties.

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26

Jingu, K., R. Umezawa, T. Yamamoto, Y. Ishikawa, N. Takahashi, K. Takeda, Y. Suzuki, S. Teramura, and S. Omata. "Radiation Therapy." Nihon Kikan Shokudoka Gakkai Kaiho 72, no. 2 (April 10, 2021): 84–87. http://dx.doi.org/10.2468/jbes.72.84.

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27

Article, Editorial. "RADIATION THERAPY." Diagnostic radiology and radiotherapy, no. 1 (April 26, 2018): 133–37. http://dx.doi.org/10.22328/2079-5343-2018-9-1-133-137.

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28

Strohl, Roberta Anne. "Radiation Therapy." Nursing Clinics of North America 25, no. 2 (June 1990): 309–29. http://dx.doi.org/10.1016/s0029-6465(22)02928-0.

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29

Haylock, Pamela J. "Radiation Therapy." American Journal of Nursing 87, no. 11 (November 1987): 1441. http://dx.doi.org/10.2307/3425900.

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30

Frassica, Deborah A., Sarah Thurman, and James Welsh. "RADIATION THERAPY." Orthopedic Clinics of North America 31, no. 4 (October 2000): 557–66. http://dx.doi.org/10.1016/s0030-5898(05)70175-9.

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31

Shipley, William U. "Radiation Therapy." Journal of Urology 147, no. 3 Part 2 (March 1992): 929–30. http://dx.doi.org/10.1016/s0022-5347(17)37425-6.

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32

Charkravarti, A., M. Wang, I. Robins, A. Guha, W. Curren, D. Brachman, C. Schultz, et al. "Radiation Therapy." Neuro-Oncology 12, Supplement 4 (October 21, 2010): iv105—iv112. http://dx.doi.org/10.1093/neuonc/noq116.s15.

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33

Behera, M. K., A. Sharma, S. Dutta, S. Sharma, P. K. Julka, G. K. Rath, W. J. Kil, et al. "RADIATION THERAPY." Neuro-Oncology 13, suppl 3 (October 21, 2011): iii127—iii133. http://dx.doi.org/10.1093/neuonc/nor160.

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34

Anwar, M., J. Lupo, A. Molinaro, J. Clarke, N. Butowski, M. Prados, S. Chang, et al. "RADIATION THERAPY." Neuro-Oncology 15, suppl 3 (November 1, 2013): iii178—iii188. http://dx.doi.org/10.1093/neuonc/not187.

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35

Jeremic, Branislav. "Radiation therapy." Hematology/Oncology Clinics of North America 18, no. 1 (February 2004): 1–12. http://dx.doi.org/10.1016/s0889-8588(03)00143-6.

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36

Brooks, Claire. "Radiation Therapy." Physiotherapy 84, no. 8 (August 1998): 387–95. http://dx.doi.org/10.1016/s0031-9406(05)61467-8.

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37

Neal Mauldin, G. "Radiation Therapy." Veterinary Clinics of North America: Small Animal Practice 26, no. 1 (January 1996): 17–27. http://dx.doi.org/10.1016/s0195-5616(96)50003-3.

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38

Brady, Luther W. "Radiation Therapy." JAMA: The Journal of the American Medical Association 258, no. 16 (October 23, 1987): 2285. http://dx.doi.org/10.1001/jama.1987.03400160139043.

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39

Duemer, Joseph. "Radiation Therapy." Chest 150, no. 6 (December 2016): 1405. http://dx.doi.org/10.1016/j.chest.2016.07.046.

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40

Torpy, Janet M. "Radiation Therapy." JAMA 294, no. 10 (September 14, 2005): 1296. http://dx.doi.org/10.1001/jama.294.10.1296.

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Jin, Jill. "Radiation Therapy." JAMA 310, no. 24 (December 25, 2013): 2691. http://dx.doi.org/10.1001/jama.2013.282757.

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42

Xie Xinlong, 谢鑫龙, 朱晓晓 Zhu Xiaoxiao, 朱嘉诚 Zhu Jiacheng та 沈为民 Shen Weimin. "非制冷热红外成像光谱仪内部杂散辐射的分析与抑制". Acta Optica Sinica 42, № 15 (2022): 1512006. http://dx.doi.org/10.3788/aos202242.1512006.

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43

Dutta, Subhajit, Raju R. Wadekar, and Tilottama Roy. "Radioprotective natural products as alternative complements in oncological radiotherapy." Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas 20, no. 2 (March 30, 2021): 101–22. http://dx.doi.org/10.37360/blacpma.21.20.2.9.

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Humans when exposed to harmful ionising radiations suffer from various pathophysiological disorders including cancer. Radiotherapy is a treatment where these cancerous cells within a tumor are targeted and killed by means of high energy waves. This therapy is very expensive and involves highly sophisticated instruments. In addition to this, most synthetic radioprotectors including Amifostine have been found to possess toxicity. This led researchers to develop a novel, economically viable, and efficient therapeutic alternative to radiation therapy. The last two decades have observed a major shift towards investigating natural products as radioprotectors, as these are immensely effective in terms of their potential bioequivalence relative to many of the established synthetic compounds available. Taking into account the limitations of radiation therapy, an approach ‘Integrative Oncology’ that involves a combination of both traditional and conventional medical treatment are used nowadays to treat patients suffering from cancer and associated mental and psychological disorders.

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Georgakilas, Alexandros G. "Role of DNA Damage and Repair in Detrimental Effects of Ionizing Radiation." Radiation 1, no. 1 (October 22, 2020): 1–4. http://dx.doi.org/10.3390/radiation1010001.

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Ionizing radiation (IR) is considered a traditional mutagen and genotoxic agent. Exposure to IR affects in all cases biological systems and living organisms from plants to humans mostly in a pernicious way. At low (<0.1 Gy) and low-to-medium doses (0.1–1 Gy), one can find in the literature a variety of findings indicating sometimes a positive-like anti-inflammatory effect or detrimental-like toxicity. In this Special Issue and in general in the current research, we would like to acquire works and more knowledge on the role(s) of DNA damage and its repair induced by ionizing radiations as instigators of the full range of biological responses to radiation. Emphasis should be given to advances offering mechanistic insights into the ability of radiations with different qualities to severely impact cells or tissues. High-quality research or review studies on different species projected to humans are welcome. Technical advances reporting on the methodologies to accurately measure DNA or other types of biological damage must be highly considered for the near future in our research community, as well. Last but not least, clinical trials or protocols with improvements to radiation therapy and radiation protection are also included in our vision for the advancement of research regarding biological effects of IR.

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45

Blakely, Eleanor A. "The 20th Gray lecture 2019: health and heavy ions." British Journal of Radiology 93, no. 1115 (November 1, 2020): 20200172. http://dx.doi.org/10.1259/bjr.20200172.

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Objective Particle radiobiology has contributed new understanding of radiation safety and underlying mechanisms of action to radiation oncology for the treatment of cancer, and to planning of radiation protection for space travel. This manuscript will highlight the significance of precise physical and biologically effective dosimetry to this translational research for the benefit of human health. This review provides a brief snapshot of the evolving scientific basis for, and the complex current global status, and remaining challenges of hadron therapy for the treatment of cancer. The need for particle radiobiology for risk planning in return missions to the Moon, and exploratory deep-space missions to Mars and beyond are also discussed. Methods Key lessons learned are summarized from an impressive collective literature published by an international cadre of multidisciplinary experts in particle physics, radiation chemistry, medical physics of imaging and treatment planning, molecular, cellular, tissue radiobiology, biology of microgravity and other stressors, theoretical modeling of biophysical data, and clinical results with accelerator-produced particle beams. Results Research pioneers, many of whom were Nobel laureates, led the world in the discovery of ionizing radiations originating from the Earth and the Cosmos. Six radiation pioneers led the way to hadron therapy and the study of charged particles encountered in outer space travel. Worldwide about 250,000 patients have been treated for cancer, or other lesions such as arteriovenous malformations in the brain between 1954 and 2019 with charged particle radiotherapy, also known as hadron therapy. The majority of these patients (213,000) were treated with proton beams, but approximately 32,000 were treated with carbon ion radiotherapy. There are 3500 patients who have been treated with helium, pions, neon or other ions. There are currently 82 facilities operating to provide ion beam clinical treatments. Of these, only 13 facilities located in Asia and Europe are providing carbon ion beams for preclinical, clinical, and space research. There are also numerous particle physics accelerators worldwide capable of producing ion beams for research, but not currently focused on treating patients with ion beam therapy but are potentially available for preclinical and space research. Approximately, more than 550 individuals have traveled into Lower Earth Orbit (LEO) and beyond and returned to Earth. Conclusion Charged particle therapy with controlled beams of protons and carbon ions have significantly impacted targeted cancer therapy, eradicated tumors while sparing normal tissue toxicities, and reduced human suffering. These modalities still require further optimization and technical refinements to reduce cost but should be made available to everyone in need worldwide. The exploration of our Universe in space travel poses the potential risk of exposure to uncontrolled charged particles. However, approaches to shield and provide countermeasures to these potential radiation hazards in LEO have allowed an amazing number of discoveries currently without significant life-threatening medical consequences. More basic research with components of the Galactic Cosmic Radiation field are still required to assure safety involving space radiations and combined stressors with microgravity for exploratory deep space travel. Advances in knowledge The collective knowledge garnered from the wealth of available published evidence obtained prior to particle radiation therapy, or to space flight, and the additional data gleaned from implementing both endeavors has provided many opportunities for heavy ions to promote human health.

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Dubey, Poornima, Mathieu Sertorio, and Vinita Takiar. "Therapeutic Advancements in Metal and Metal Oxide Nanoparticle-Based Radiosensitization for Head and Neck Cancer Therapy." Cancers 14, no. 3 (January 20, 2022): 514. http://dx.doi.org/10.3390/cancers14030514.

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Although radiation therapy (RT) is one of the mainstays of head and neck cancer (HNC) treatment, innovative approaches are needed to further improve treatment outcomes. A significant challenge has been to design delivery strategies that focus high doses of radiation on the tumor tissue while minimizing damage to surrounding structures. In the last decade, there has been increasing interest in harnessing high atomic number materials (Z-elements) as nanoparticle radiosensitizers that can also be specifically directed to the tumor bed. Metallic nanoparticles typically display chemical inertness in cellular and subcellular systems but serve as significant radioenhancers for synergistic tumor cell killing in the presence of ionizing radiation. In this review, we discuss the current research and therapeutic efficacy of metal nanoparticle (MNP)-based radiosensitizers, specifically in the treatment of HNC with an emphasis on gold- (AuNPs), gadolinium- (AGdIX), and silver- (Ag) based nanoparticles together with the metallic oxide-based hafnium (Hf), zinc (ZnO) and iron (SPION) nanoparticles. Both in vitro and in vivo systems for different ionizing radiations including photons and protons were reviewed. Finally, the current status of preclinical and clinical studies using MNP-enhanced radiation therapy is discussed.

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GÜL, İbrahim Etem, and Sinan KUDAY. "Retinoblastoma Radiotherapy Treatment Optimizations Through GATE Simulations." Cumhuriyet Science Journal 43, no. 4 (December 27, 2022): 708–15. http://dx.doi.org/10.17776/csj.1152691.

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One of the most frequent children tumors in the area around the eyes is defined as retinoblastoma. Proton radiotherapy treatment is a particularly effective type of radiation therapy due to the prolonged survival rates of children with childhood cancers such as retinablastoma, continued growth of nearby organs and tissues, low radiation dose restriction of vision-related tissues and systems of these tissues. In this study, a geometry phantom including eyeball, lens, lacrimal gland, optic nerve, optic chiasm, retina, cancer, cornea and bone structures was modeled with Monte Carlo simulation tool GATE (vGATE 9.0). With this simulation, the doses absorbed by the tissues were calculated using the DoseActor and TLEDoseActor algorithms. Secondary doses were determined by the TLEDoseActor algorithm. Determination of secondary radiations is important because of the low radiation dose limit of tissues and systems that affect vision. The best treatment results were tried to be obtained by giving the beam thickness of the radiation used in our study, 4 different angles towards the target and different energies. These results show that it can be helpful in calculating a treatment plan for proton therapy in clinical practice.

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Sheino, Igor N., Vyacheslav F. Khokhlov, and Pavel V. Izhevskiy. "Development of the Binary Technologies for Radiation Therapy of Malignant Tumors – Current State and Problems." Advanced Materials Research 1084 (January 2015): 369–72. http://dx.doi.org/10.4028/www.scientific.net/amr.1084.369.

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The study analyses the current status and prospects of development of new radiation therapy methods, such as neutron capture therapy (NCT) and photon capture therapy (PCT), based on elements having high interaction cross section with radiations, to identify the benefits in their clinical application. One of the problems of NCT is the lack (or unavailability) of neutron sources with required intensity and spectrum. National Research Tomsk Polytechnic University has an opportunity of carrying out clinical studies, due to the presence of operating research nuclear reactor. However, the development of the medical neutron channel at this reactor is extremely challenging.

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Lu, D., E. Xanthopoulos, N. Dixit, P. James, N. Mitra, W. Levin, R. Rengan, S. M. Hahn, S. Both, and C. B. Simone. "Comparison of Intensity Modulated Radiation Therapy, Adaptive Radiation Therapy, Proton Radiation Therapy, and Adaptive Proton Radiation Therapy for Small Cell Lung Cancer." International Journal of Radiation Oncology*Biology*Physics 87, no. 2 (October 2013): S510. http://dx.doi.org/10.1016/j.ijrobp.2013.06.1349.

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50

Stary, O. "EFFECT OF NORMALIZING HEATING OF FERRITE COMPACTS ON COMPACTION DURING RADIATION-THERMAL SINTERING." Eurasian Physical Technical Journal 18, no. 3 (37) (September 24, 2021): 11–14. http://dx.doi.org/10.31489/2021no3/11-14.

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The study investigated linear shrinkage of lithium-titanium ferrite samples during radiation-thermal and thermal sintering. Prior to compaction, part of the powders were subjected to thermal heating for 2h at temperatures of 1273, 1373, and 1473 K. It is found that changes in the shrinkage kinetics of ferrites after powder annealing are consistent with the classical concepts of thermal deexcitation of powders due to annealing of defects. Such defects were formed in powder grains during grinding. The obtained data analysis allowed us to offer the most likely model for radiation-thermal activation of powder ferrite sintering. This is a model of radiation inhibition of non-equilibrium defects relaxation.

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