Добірка наукової літератури з теми "Protein targeted lead molecule"
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Статті в журналах з теми "Protein targeted lead molecule"
Hyun, Soonsil, and Dongyun Shin. "Chemical-Mediated Targeted Protein Degradation in Neurodegenerative Diseases." Life 11, no. 7 (June 24, 2021): 607. http://dx.doi.org/10.3390/life11070607.
Повний текст джерелаGiardina, Sarah F., Elena Valdambrini, Michael Peel, Manny D. Bacolod, Mace L. Rothenberg, Richard B. Lanman, J. David Warren, and Francis Barany. "Cure-PROs: Next-generation targeted protein degraders." Journal of Clinical Oncology 41, no. 16_suppl (June 1, 2023): e15101-e15101. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e15101.
Повний текст джерелаMusielak, Bogdan, Weronika Janczyk, Ismael Rodriguez, Jacek Plewka, Dominik Sala, Katarzyna Magiera-Mularz, and Tad Holak. "Competition NMR for Detection of Hit/Lead Inhibitors of Protein–Protein Interactions." Molecules 25, no. 13 (July 1, 2020): 3017. http://dx.doi.org/10.3390/molecules25133017.
Повний текст джерелаThomas, Bedwyr ab Ion, H. Lois Lewis, D. Heulyn Jones, and Simon E. Ward. "Central Nervous System Targeted Protein Degraders." Biomolecules 13, no. 8 (July 25, 2023): 1164. http://dx.doi.org/10.3390/biom13081164.
Повний текст джерелаDas, Debanu, Matthew Duncton, Patricia Pellicena, Ashley Deacon, David Wilson, and Millie Georgiadis. "Development of a DNA damage response (DDR) therapeutics platform for oncology." Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021): e15036-e15036. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e15036.
Повний текст джерелаMilosevic, Ivana. "Resistance to targeted therapy in chronic lymphocytic leukemia." Medical review 75, Suppl. 1 (2022): 57–61. http://dx.doi.org/10.2298/mpns22s1057m.
Повний текст джерелаQokoyi, Ndibonani Kebonang, Priscilla Masamba, and Abidemi Paul Kappo. "Proteins as Targets in Anti-Schistosomal Drug Discovery and Vaccine Development." Vaccines 9, no. 7 (July 8, 2021): 762. http://dx.doi.org/10.3390/vaccines9070762.
Повний текст джерелаOlsen, Sarah Naomi, Laura Godfrey, James P. Healy, Charles Hatton, and Scott A. Armstrong. "Abstract 681: Targeted MLL-AF9 degradation is phenocopied by combined DOT1L and Menin inhibition." Cancer Research 82, no. 12_Supplement (June 15, 2022): 681. http://dx.doi.org/10.1158/1538-7445.am2022-681.
Повний текст джерелаKhattri, Ram B., Daniel L. Morris, Stephanie M. Bilinovich, Erendra Manandhar, Kahlilah R. Napper, Jacob W. Sweet, David A. Modarelli, and Thomas C. Leeper. "Identifying Ortholog Selective Fragment Molecules for Bacterial Glutaredoxins by NMR and Affinity Enhancement by Modification with an Acrylamide Warhead." Molecules 25, no. 1 (December 30, 2019): 147. http://dx.doi.org/10.3390/molecules25010147.
Повний текст джерелаYang, Kylie, Jacek L. Kolanowski, and Elizabeth J. New. "Mitochondrially targeted fluorescent redox sensors." Interface Focus 7, no. 2 (April 6, 2017): 20160105. http://dx.doi.org/10.1098/rsfs.2016.0105.
Повний текст джерелаДисертації з теми "Protein targeted lead molecule"
Nilsson, Jonas. "Design, Synthesis and Characterization of Small Molecule Inhibitors and Small Molecule : Peptide Conjugates as Protein Actors." Doctoral thesis, Linköpings universitet, Organisk Kemi, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-3943.
Повний текст джерелаNacheva, Katya Pavlova. "Development of a Bio-Molecular Fluorescent Probe Used in Kinetic Target-Guided Synthesis for the Identification of Inhibitors of Enzymatic and Protein-Protein Interaction Targets." Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4376.
Повний текст джерелаVerow, Mark. "The development and validation of small molecule inhibitors targeted against the HIV-l Nef protein." Thesis, University of Leeds, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659183.
Повний текст джерелаOmar, Hany Ahmed Mostafa Mohamed. "Molecular Pharmacology and Preclinical Studies of Novel Small-molecule Targeted Agents for The Treatment of Hepatocellular Carcinoma." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1290565602.
Повний текст джерелаFarrington, Caroline Cain. "TARGETED DEGRADATION OF THE MYC ONCOGENE USING PP2AB56ALPHASELECTIVE SMALL MOLECULE MODULATORS OF PROTEINPHOSPHATASE 2A AS A THERAPEUTIC STRATEGY FOR TREATING MYCDRIVENCANCERS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1579905487094187.
Повний текст джерелаLu, Felice. "Protein inhibition by targeted small molecule libraries /." 2005. http://wwwlib.umi.com/dissertations/search.
Повний текст джерелаMatos, Ana Marta de Jesus Gomes de. "From a multitarget antidiabetic glycosyl isoflavone towards new molecular entities against diabetes and Alzheimer’s disease : generation of lead series and target assessment." Doctoral thesis, 2018. http://hdl.handle.net/10451/42532.
Повний текст джерелаBhowmick, Tuhin. "Crystal Structure Of Mycobacterium Tuberculosis Histone Like Protein HU And Structure Based Design Of Molecules To Inhibit MtbHU-DNA Interaction : Leads For A New Target. Structure Aided Computational Analysis Of Metal Coordinated Complexes Containing Amino Acids And Organic Moieties Designed For Photo Induced DNA Cleavage." Thesis, 2012. http://hdl.handle.net/2005/2469.
Повний текст джерелаКниги з теми "Protein targeted lead molecule"
Cui, Zhao, Neil Turner, and Ming-hui Zhao. Alport post-transplant antiglomerular basement membrane disease. Edited by Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0075.
Повний текст джерелаColbert, Robert A., and Paul Bowness. Immune mechanisms: HLA-B27. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198734444.003.0006.
Повний текст джерелаMalcangio, Marzia. Glia. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0035.
Повний текст джерелаBeattie, R. Mark, Anil Dhawan, and John W.L. Puntis. The pancreas. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569862.003.0046.
Повний текст джерелаGropman, Andrea L., Belen Pappa, and Nicholas Ah Mew. The Urea Cycle Disorders. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0063.
Повний текст джерелаЧастини книг з теми "Protein targeted lead molecule"
Weber, L. "Discovery of New MCRs, Chemical Evolution and Lead Optimization." In Small Molecule — Protein Interactions, 189–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-662-05314-0_12.
Повний текст джерелаWhitty, Adrian. "Small-Molecule Inhibitors of Protein-Protein Interactions: Challenges and Prospects." In Gene Family Targeted Molecular Design, 199–233. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470423936.ch7.
Повний текст джерелаUrsu, Andrei, Matthew G. Costales, Jessica L. Childs-Disney, and Matthew D. Disney. "Chapter 15. Small-molecule Targeted Degradation of RNA." In Protein Degradation with New Chemical Modalities, 317–36. Cambridge: Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839160691-00317.
Повний текст джерелаPrakash, Om, and Feroz Khan. "CoSSDb: A Database of Co-crystallized Ligand Sub-structures for Anticancer Lead Designing & Optimization." In Proceedings of the Conference BioSangam 2022: Emerging Trends in Biotechnology (BIOSANGAM 2022), 133–41. Dordrecht: Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-020-6_14.
Повний текст джерелаSharma, Sahil, and Cynthia M. Sharma. "Identification of RNA Binding Partners of CRISPR-Cas Proteins in Prokaryotes Using RIP-Seq." In Methods in Molecular Biology, 111–33. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1851-6_6.
Повний текст джерелаJayaraj, Abhilash, Ruchika Bhat, Amita Pathak, Manpreet Singh, and B. Jayaram. "Development of a Web-Server for Identification of Common Lead Molecules for Multiple Protein Targets." In Methods in Pharmacology and Toxicology, 487–504. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/7653_2018_9.
Повний текст джерелаTakaoka, Yousuke, and Minoru Ueda. "Enantiodifferential Approach for the Target Protein Detection of the Jasmonate Glucoside That Controls the Leaf Closure of Samanea saman." In Methods in Molecular Biology, 149–58. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7874-8_13.
Повний текст джерелаRamos, Kenneth S., Stefano Guerra, and Randa El-Zein. "Precision Medicine Approaches for Stratification and Development of Novel Therapies of Latin(x) Patients at Risk of Lung Malignancy." In Advancing the Science of Cancer in Latinos, 89–98. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-14436-3_8.
Повний текст джерелаDas, Amit, and Simanti Bhattacharya. "Different Types of Molecular Docking Based on Variations of Interacting Molecules." In Pharmaceutical Sciences, 795–819. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-1762-7.ch031.
Повний текст джерелаDas, Amit, and Simanti Bhattacharya. "Different Types of Molecular Docking Based on Variations of Interacting Molecules." In Methods and Algorithms for Molecular Docking-Based Drug Design and Discovery, 148–72. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-5225-0115-2.ch006.
Повний текст джерелаТези доповідей конференцій з теми "Protein targeted lead molecule"
Quertermous, T., J. M. Schnee, M. S. Runge, G. R. Matsueda, N. W. Hudson, J. G. Seidman, and E. Haber. "EXPRESSION OF A RECOMBINANT ANTIBODY-TARGETED THROMBOLYTIC MOLECULE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644616.
Повний текст джерелаTurchi, John, Katherine S. Pawelczak, Navnath Gavande, and Pamela S. VanderVere-Carozza. "Abstract A095: Targeting protein-DNA interactions in the DNA damage response: Lead identification and optimization for novel inhibitors of RPA and Ku." In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-a095.
Повний текст джерелаChen, Kok Hao, and Jong Hyun Choi. "DNA Oligonucleotide-Templated Nanocrystals: Synthesis and Novel Label-Free Protein Detection." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-11958.
Повний текст джерелаSarkar, Saugata, and Marissa Nichole Rylander. "Treatment Planning Model for Nanotube-Mediated Laser Cancer Therapy." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192997.
Повний текст джерелаTavousi, Pouya, Morad Behandish, Kazem Kazerounian, and Horea T. Ilieş. "An Improved Free Energy Formulation and Implementation for Kinetostatic Protein Folding Simulation." In ASME 2013 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/detc2013-12671.
Повний текст джерелаHussein, Ola, Feras Alali, Ala‐Eddin Al Mustafa, and Ashraf Khalil. "Development of Novel Chalcone Analogs as Potential Multi-Targeted Therapies for Castration-Resistant Prostate Cancer." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0114.
Повний текст джерелаVieira, Daniella Serafin Couto, Laura Otto Walter, Ana Carolina Rabello de Moraes, João Péricles da Silva Jr, and Maria Cláudia Santos Silva. "CROSS-SECTIONAL ANALYSIS OF CLINICAL AND MORPHOLOGICAL FACTORS OF BREAST CANCER IMMUNOPHENOTYPES: A COMPARATIVE STUDY OF TWO DIFFERENT METHODOLOGIES OVER A 24‑YEAR HISTORICAL SERIES." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1043.
Повний текст джерелаBrewer, Bryson M., Yandong Gao, Rebecca M. Sappington, and Deyu Li. "Microfluidic Molecular Trap: Probing Extracellular Signaling by Selectively Blocking Exchange of Specific Molecules in Cell-Cell Interactions." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-64489.
Повний текст джерелаHussein, Ola, Feras Alali, Ala-Eddin Al Moustafa, and Ashraf Khalil. "Design, Synthesis and Biological Evaluation of Novel Chalcone Analogs as Potential Therapeutic Agents for Castration-Resistant Prostate Cancer." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0179.
Повний текст джерелаImai, Yohsuke, Hitoshi Kondo, Young Ho Kang, Takuji Ishikawa, Chwee Teck Lim, and Takami Yamaguchi. "A Numerical Model of Adhesion Property of Malaria Infected Red Blood Cells in Micro Scale Blood Flows." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206456.
Повний текст джерелаЗвіти організацій з теми "Protein targeted lead molecule"
Gafni, Yedidya, and Vitaly Citovsky. Molecular interactions of TYLCV capsid protein during assembly of viral particles. United States Department of Agriculture, April 2007. http://dx.doi.org/10.32747/2007.7587233.bard.
Повний текст джерелаTzfira, Tzvi, Michael Elbaum, and Sharon Wolf. DNA transfer by Agrobacterium: a cooperative interaction of ssDNA, virulence proteins, and plant host factors. United States Department of Agriculture, December 2005. http://dx.doi.org/10.32747/2005.7695881.bard.
Повний текст джерелаLapidot, Moshe, and Vitaly Citovsky. molecular mechanism for the Tomato yellow leaf curl virus resistance at the ty-5 locus. United States Department of Agriculture, January 2016. http://dx.doi.org/10.32747/2016.7604274.bard.
Повний текст джерелаOhad, Nir, and Robert Fischer. Regulation of Fertilization-Independent Endosperm Development by Polycomb Proteins. United States Department of Agriculture, January 2004. http://dx.doi.org/10.32747/2004.7695869.bard.
Повний текст джерелаWilson, Thomas E., Avraham A. Levy, and Tzvi Tzfira. Controlling Early Stages of DNA Repair for Gene-targeting Enhancement in Plants. United States Department of Agriculture, March 2012. http://dx.doi.org/10.32747/2012.7697124.bard.
Повний текст джерелаCitovsky, Vitaly, and Yedidya Gafni. Suppression of RNA Silencing by TYLCV During Viral Infection. United States Department of Agriculture, December 2009. http://dx.doi.org/10.32747/2009.7592126.bard.
Повний текст джерелаMeir, Shimon, Michael S. Reid, Cai-Zhong Jiang, Amnon Lers, and Sonia Philosoph-Hadas. Molecular Studies of Postharvest Leaf and Flower Senescence. United States Department of Agriculture, January 2011. http://dx.doi.org/10.32747/2011.7592657.bard.
Повний текст джерелаGafni, Yedidya, and Vitaly Citovsky. Inactivation of SGS3 as Molecular Basis for RNA Silencing Suppression by TYLCV V2. United States Department of Agriculture, November 2013. http://dx.doi.org/10.32747/2013.7593402.bard.
Повний текст джерелаTucker, Mark L., Shimon Meir, Amnon Lers, Sonia Philosoph-Hadas, and Cai-Zhong Jiang. Elucidation of signaling pathways that regulate ethylene-induced leaf and flower abscission of agriculturally important plants. United States Department of Agriculture, January 2012. http://dx.doi.org/10.32747/2012.7597929.bard.
Повний текст джерелаGafni, Yedidya, Moshe Lapidot, and Vitaly Citovsky. Dual role of the TYLCV protein V2 in suppressing the host plant defense. United States Department of Agriculture, January 2013. http://dx.doi.org/10.32747/2013.7597935.bard.
Повний текст джерела