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Книги з теми "Prone proteins"

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Автор: Grafiati

Опубліковано: 6 вересня 2023

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1

R, Ansari Rafat, and United States. National Aeronautics and Space Administration., eds. A fiber optic probe for monitoring protein aggregation, nucleation, and crystallization. Washington, DC: National Aeronautics and Space Administration, 1997.

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2

Keromnes, Anne. Synthesis of a novel chemically modified tetrasaccharide to probe carbohydrate-protein interactions. Birmingham: University of Birmingham, 1996.

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3

Prof, Miller Lawrence W., ed. Probes and tags to study biomolecular function: For proteins, RNA, and membranes. Weinheim: Wiley-VCH Verlag, 2008.

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4

Pieribone, Vincent. Aglow in the dark: The revolutionary science of biofluorescence. Cambridge, Mass: Belknap Press of Harvard University Press, 2005.

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5

Min, Zhang, Yin Bin-Cheng, and SpringerLink (Online service), eds. Nano-Bio Probe Design and Its Application for Biochemical Analysis. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012.

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6

Les recettes Dukan: Mon re gime en 350 recettes. Paris: J'ai lu, 2008.

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7

Les recettes Dukan: Mon régime en 350 recettes. [Paris]: Flammarion, 2011.

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8

Nanomedicine. Austin, Tex: Landes Bioscience, 1999.

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9

Anna, Brajter-Toth, and Chambers James Q, eds. Electroanalytical methods for biological materials. New York: Marcel Dekker, 2002.

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10

Tinker-Mill, Claire Louisa. Nanoscale Imaging and Characterisation of Amyloid-β. Springer International Publishing AG, 2016.

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11

Tinker-Mill, Claire Louisa. Nanoscale Imaging and Characterisation of Amyloid-β. Springer London, Limited, 2016.

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12

Devi, Lakshmi A. The G Protein-Coupled Receptors Handbook (Contemporary Clinical Neuroscience). Humana Press, 2005.

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13

Prunty, Helen, Jamie L. Fraser, Charles P. Venditti, and Robin H. Lachmann. Branched Chain Amino Acids. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0016.

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Анотація:

This chapter describes the four most common disorders affecting the degradation of branched chain amino acids: maple syrup urine disease, methylmalonic acidemia, propionic acidemia and isovaleric acidemia. These conditions most commonly present with encephalopathy in the newborn period, although cases with later onset have also been described. Although adult patients are less prone to acute metabolic decompensations, they do develop a number of long-term complications, both neurological and visceral. Management shares features with other disorders of protein metabolism and centers on a low-protein diet and the use of disease-specific amino acid supplements.

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14

Chen, Lin Xiang-Qun. Ultrafast studies of the dynamics of peptides and proteins: Using tryptophan as a probe. 1988.

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15

Brahm, Amanda J., and Robert A. Hegele. Monogenic Chylomicronemia: Deficiency of Lipoprotein Lipase and Related Factors. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199972135.003.0033.

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Monogenic chylomicronemia is an autosomal recessive condition characterized by severely elevated fasting triglyceride that carries lifelong elevated risk of developing pancreatitis. The majority of cases are caused by mutations in the LPL gene encoding lipoprotein lipase, the enzyme primarily responsible for chylomicron clearance. Mutations in genes encoding associated proteins (APOC2, APOA5, GPIHBP1 and LMF1) may also present with a very similar phenotype. Current management, which includes restriction of dietary fat intake and standard pharmacologic interventions, has met with limited success, but new therapies under development may prove to be more effective.

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16

Hussain, Ibrahim, and David H. Gutmann. Familial CNS Tumor Syndromes. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0134.

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Neurofibromatosis type 1 (NF1) is an inherited cancer predisposition syndrome affecting 1 in 2,500 to 3,000 individuals worldwide. Key clinical features of NF1 include pigmentary abnormalities, learning disabilities, and orthopedic problems. Individuals with NF1 are prone to the development of benign peripheral nerve sheath tumors, and 15% to 20% of affected children harbor low-grade gliomas of the optic pathway. Since the discovery of the NF1 gene and its protein neurofibromin, advances in understanding the molecular mechanisms of NF1 have resulted in the discovery of new treatments. In addition, genetically-engineered animal models of NF1-associated tumorigenesis have served as platforms for validating molecular targets for future medical therapies.

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17

Avesani, Carla Maria, Juan Jesús Carrero, Bengt Lindholm, and Peter Stenvinkel. Nutritional screening and nutritional management in dialysis patients. Edited by Jonathan Himmelfarb. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0274.

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Patients on dialysis are prone to nutritional disturbances, that is, protein-energy wasting, obesity, and imbalance in body fluids and in serum phosphorus and potassium equilibrium. Hence, specialized nutritional care is highly important and include (a) a carefully assessment of the nutritional status, (b) prescription of diet with adequate energy and nutrients to treat and prevent the development of nutritional disturbances often observed in these patients, and (c) periodic follow-up to check adherence of the prescribed diet as well as to evaluate the nutritional status and efficacy of the dietary intervention. This chapter discusses these three aspects in detail and will guide nephrologists and dieticians when treating dialysed patients.

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18

Latinas: An anthology of struggles & protests in 21st century USA. RED SUGARCANE PRESS INC., 2018.

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19

BURAVTSEVA, T. V., I. N. PERCHUK, A. E. SOLOVEVA, M. V. GURKINA, and G. P. EGOROVA. COMMON BEAN (PHASEOLUS VULGARIS L.): ASSESSMENT OF PROTEIN CONTENT IN SEEDS WITH BRIEF DESCRIPTION OF USEFUL AGRONOMIC TRAITS. N.I. Vavilov All-Russian Institute of Plant Genetic Resources, 2021. http://dx.doi.org/10.30901/978-5-907145-73-3.

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The catalogue contains the results of protein content assessment in seeds of 216 common bean (Phaseolus vulgaris L.) accessions from the VIR plant genetic resources collection. The data of a long-term study with mean values of characters for each accession are presented. The study of main agronomic characters in the accessions was conducted from 2004 through 2018 in the experimental fields at Astrakhan Experiment Station of VIR. The accessions are described employing eight morphological and agronomic characters important for breeding practice. This catalogue is intended to serve as a tool in source material selection for further breeding process. It may prove helpful for plant breeders and grain legume experts.

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20

(Editor), W. E. Balch, Channing J. Der (Editor), and Alan Hall (Editor), eds. Regulators and Effectors of Small GTPases: Ras Family, Volume 407 (Methods in Enzymology). Academic Press, 2006.

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21

Pieribone, Vincent, and David F. Gruber. Aglow in the Dark: The Revolutionary Science of Biofluorescence. Belknap Press, 2006.

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22

Zhang, Min, Bang-Ce Ye, and Bin-Cheng Yin. Nano-Bio Probe Design and Its Application for Biochemical Analysis. Springer, 2012.

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23

Zhang, Min, Bang-Ce Ye, and Bin-Cheng Yin. Nano-Bio Probe Design and Its Application for Biochemical Analysis. Springer, 2012.

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24

Graves, Michael V. Analysis of two highly expressed genes from Chlorella virus PBCV- 1: Prote in characterization and the DNA sequences of the major capsid protein gene and the early/late 33-kDa protein gene. 1991.

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25

Jörres, Achim, Dietrich Hasper, and Michael Oppert. Non-dialytic management of the patient with acute kidney injury. Edited by Norbert Lameire. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0228.

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The main focus in the non-dialytic management of patients with acute kidney injury (AKI) is the prevention and treatment of complications.Nutritional support is an important aspect as many patients tend to be hypercatabolic, thus requiring adequate caloric intake, yet without administration of excessive fluid volumes. Inadequate nutrition in AKI may lead to enhanced production of urea nitrogen and azotaemia. However, hyperglycaemia is a frequent complication in these patients, often requiring continuous insulin therapy to achieve the recommended blood glucose target range of 110–150 mg/dL (6.11–8.33 mmol/L).Patients with AKI are prone to infections which are a common cause of death in this population. Careful search for and intensive treatment of infections is therefore of utmost importance, and antimicrobial chemotherapy must be initiated as early as possible, especially in patients with sepsis and AKI.Drug dosing in patients with AKI is complex and difficult. Residual kidney function can be highly variable and drug disposition may be altered due to changes in distribution volume, protein binding, and metabolism. Moreover, many drugs can be removed by renal replacement therapy (RRT). Therefore, adequate dosing must take into account the patient’s individual clinical characteristics, the specific pharmacokinetic/pharmacodynamic properties of the drug, and the mode and intensity of renal replacement therapy.

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26

Voinescu, Alexandra, Nadia Wasi Iqbal, and Kevin J. Martin. Management of chronic kidney disease-mineral and bone disorder. Edited by David J. Goldsmith. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0118_update_001.

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In all patients with chronic kidney disease (CKD) stages 3–5, regular monitoring of serum markers of CKD-mineral and bone disorder, including calcium (Ca), phosphorus (P), parathyroid hormone (PTH), 25-hydroxyvitamin D, and alkaline phosphatase, is recommended. Target ranges for these markers are endorsed by guidelines. The principles of therapy for secondary hyperparathyroidism include control of hyperphosphataemia, correction of hypocalcaemia, use of vitamin D sterols, use of calcimimetics, and parathyroidectomy. of hyperphosphataemia is crucial and may be achieved by means of dietary P restriction, use of P binders, and P removal by dialysis. Dietary P restriction requires caution, as it may be associated with protein malnutrition. Aluminium salts are effective P binders, but they are not recommended for long-term use, as Aluminium toxicity (though from contaminated dialysis water rather than oral intake) may cause cognitive impairment, osteomalacia, refractory microcytic anaemia, and myopathy. Ca-based P binders are also quite effective, but should be avoided in patients with hypercalcaemia, vascular calcifications, or persistently low PTH levels. Non-aluminium, non-Ca binders, like sevelamer and lanthanum carbonate, may be more adequate for such patients; however, they are expensive and may have several side effects. Furthermore, comparative trials have failed so far to provide conclusive evidence on the superiority of these newer P binders over Ca-based binders in terms of preventing vascular calcifications, bone abnormalities, and mortality. P removal is about 1800–2700 mg per week with conventional thrice-weekly haemodialysis, but may be increased by using haemodiafiltration or intensified regimens, such as short daily, extended daily or three times weekly nocturnal haemodialysis. Several vitamin D derivatives are currently used for the treatment of secondary hyperparathyroidism. In comparison with the natural form calcitriol, the vitamin D analogue paricalcitol seems to be more fast-acting and less prone to induce hypercalcaemia and hyperphosphataemia, but whether these advantages translate into better clinical outcomes is unknown. Calcimimetics such as cinacalcet can significantly reduce PTH, Ca, and P levels, but they have failed to definitively prove any benefits in terms of mortality and cardiovascular events in dialysis patients. Parathyroidectomy is often indicated in CKD patients with severe persistent hyperparathyroidism, refractory to aggressive medical treatment with vitamin D analogues and/or calcimimetics. This procedure usually leads to rapid improvements in biochemical markers (i.e. significant lowering of serum Ca, P, and PTH) and clinical manifestations (such as pruritus and bone pain); however, the long-term benefits are still unclear.

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27

Stibor, Ivan. Anion Sensing. Springer, 2014.

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28

Anion Sensing. Springer, 2005.

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29

Freitas, Robert A. Nanomedicine: Biocompatibility. Not Avail, 2004.

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30

Nanomedicine, Volume I: Basic Capabilities. Landes Bioscience, 1999.

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31

Furst, Eric M., and Todd M. Squires. Microrheology. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199655205.001.0001.

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We present a comprehensive overview of microrheology, emphasizing the underlying theory, practical aspects of its implementation, and current applications to rheological studies in academic and industrial laboratories. Key methods and techniques are examined, including important considerations to be made with respect to the materials most amenable to microrheological characterization and pitfalls to avoid in measurements and analysis. The fundamental principles of all microrheology experiments are presented, including the nature of colloidal probes and their movement in fluids, soft solids, and viscoelastic materials. Microrheology is divided into two general areas, depending on whether the probe is driven into motion by thermal forces (passive), or by an external force (active). We present the theory and practice of passive microrheology, including an in-depth examination of the Generalized Stokes-Einstein Relation (GSER). We carefully treat the assumptions that must be made for these techniques to work, and what happens when the underlying assumptions are violated. Experimental methods covered in detail include particle tracking microrheology, tracer particle microrheology using dynamic light scattering and diffusing wave spectroscopy, and laser tracking microrheology. Second, we discuss the theory and practice of active microrheology, focusing specifically on the potential and limitations of extending microrheology to measurements of non-linear rheological properties, like yielding and shear-thinning. Practical aspects of magnetic and optical tweezer measurements are preseted. Finally, we highlight important applications of microrheology, including measurements of gelation, degradation, high-throughput rheology, protein solution viscosities, and polymer dynamics.

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32

Smith, Christopher J. Dancing Revolution. University of Illinois Press, 2019. http://dx.doi.org/10.5622/illinois/9780252042393.001.0001.

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This book is a social history, theorizing participatory dance in New World public spaces as a tool that has enabled subaltern communities’ political resistance to hegemonic control. Drawing upon musicology, ethnomusicology, iconography, anthropology, dance studies, and folklore, and spanning examples from the eighteenth through the twenty-first century, it identifies recurrent strategic patterns in the music, movement, and “noise” that political minorities--including persons of color, economic underclasses, women, gays, and other resistance movements--have employed to oppose, contest, and transgress dominant cultures’ social control. The book applies multidisciplinary analytical practices to movement and sound in historical idioms, little documented by period scholarship, whose data are indirect, inferential, and reconstructive. Case studies include frontier Pentecostalism; Native American resistance; Shakerism; African American communities; the English- and French-speaking Caribbean; film and theatrical dance; the Stonewall Uprising and Chicago 1968 protests; twentieth-century noise ordinances; and punk-rock, hip hop, and twenty-first-century global protest movements. Examples in diverse media, from prose description to watercolor to film, are selected in order to showcase the consistency of these political understandings across diverse situations and to demonstrate the synthesis of analytical approaches, which this topic mandates. The book argues for understanding participatory music and motion--bodies and sound interacting in contested public spaces--as a central, intentional, effective, and recurrent resistance strategy in American social history.

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33

Saido, Takaomi. A-Beta Metabolism and Alzheimer's Disease. Landes Bioscience, 2003.

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34

Alonso, Alex. Paul Muldoon in America. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198859659.001.0001.

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Анотація:

Paul Muldoon was looking west long before he left Ireland for the United States in 1987, and his transatlantic departure would prove to be a turning point in his life and work. In America, where he now lives as a US citizen, Muldoon’s creative repertoire has extended into song writing, libretti, and literary criticism, while his poetry collections have themselves extended to outlandish proportions, typified in recent years by a level of formal intensity that is unique in modern poetry. To leave Northern Ireland, though, is not necessarily to leave it behind. Muldoon has spoken of his ‘sense of belonging to several places at once’, and in the United States his work has found another creative gear, new modes of performance facilitated by his Irish émigré status. This book approaches the protean work of his American period, focusing on Muldoon’s expansive structural imagination, his investment in Eros and errors, the nimbleness of his allusive practice as both a reader and writer, and the mobility of his transatlantic position. It draws on archival research to produce provocative new readings of Muldoon’s later works. Exploring the poetic and literary-critical ‘long forms’ that are now his hallmark, this book places the most significant works of Muldoon’s American period under the microscope, and opens up the intricate formal schemes of a poet Mick Imlah credits as having ‘reinvented the possibilities of rhyme for our time’.

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35

(Editor), John N. Abelson, Melvin I. Simon (Editor), Barry L. Karger (Editor), and William Hancock (Editor), eds. Methods of High Resolution Separation and Analysis of Biological Macromolecules : Fundamentals (Methods in Enzymology Series, Vol 270, Part A) (Methods in Enzymology). Academic Press, 1996.

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