Статті в журналах: "Prognathism"

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Kim, Hwikang, Dongsun Shin, Jaehyun Kang, Seewoon Kim, Hunjun Lim, Jun Lee, and Bongchul Kim. "Anatomical Characteristics of the Lateral Pterygoid Muscle in Mandibular Prognathism." Applied Sciences 11, no. 17 (August 28, 2021): 7970. http://dx.doi.org/10.3390/app11177970.

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Mandibular prognathism is one of the most concerning subjects in the oral and maxillofacial fields. In our previous studies, we attempted to clarify the etiology of mandibular prognathism. They revealed that one of the major characteristics of mandibular prognathism was the lower volume/length ratio of the mandibular condyle and body compared to normal, and the masseter muscle showed parallelism with this. This study aimed to evaluate the relationship between mandibular prognathism and the lateral pterygoid muscle by measuring the orientation and volume/length ratio of the lateral pterygoid muscle. Computed tomography was used to calculate the volume/length ratio of the lateral pterygoid muscle in 60 Korean individuals. Mimics 10.0 and Maya version 2018 were used to reconstruct the surface area and surface planes. The results showed that the prognathic group showed smaller lateral pterygoid volume/length ratios compared to the normal group (p < 0.05). In addition, the normal group displayed a larger horizontal angle (p < 0.05) to the mandibular and palatal planes than the prognathic group. This demonstrated that the mechanical drawback of the lateral pterygoid in the prognathic group is associated with mandibular prognathism.

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Mehta, Siddharth, Surendra Lodha, Ashima Valiathan, and Arun Urala. "Mandibular morphology and pharyngeal airway space: A cephalometric study." APOS Trends in Orthodontics 5 (December 29, 2014): 22–28. http://dx.doi.org/10.4103/2321-1407.148021.

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Introduction Mandibular retrognathism is considered to be the most important risk factor for upper airway obstruction. Aim This cross-sectional study intended to examine the relationship between craniofacial morphology and the pharyngeal airway space (PAS) in patients with mandibular retrognathism and mandibular prognathism, when compared to normal subjects. The study also analyzed the influence of mandibular morphology on pharyngeal length (PL). Materials and Methods The PAS was assessed in 92 females (age 15-30 years) further divided into three groups - Group 1- normal mandible (76°≤ SNB ≤82°; n = 31); Group 2-mandibular retrognathism (SNB <76°; n = 31); Group 3-Mandibular prognathism (SNB >82°; n = 30). All subjects were examined by lateral cephalometry with head position standardized using an inclinometer. Craniocervical angulation, uvula length, thickness and angulation were compared among different groups. Results The results showed no statistically significant difference in the pharyngeal airway between the three groups. Measurements of PL showed statistically significant higher values for retrognathic mandible group than normal and prognathic mandible group. Conclusion There is no significant difference between PAS between patients with mandibular retrognathism, normal mandible and mandibular prognathism. Mandibular retrognathism patients show a significantly higher uvula angulation than patients with mandibular prognathism. Craniocervical angulation showed maximum value in retrognathic mandible group followed by normal and prognathic mandible group respectively. Mean PL for retrognathic mandible patients was significantly higher than prognathic mandible patients.

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Yang, Ji Ho, Dong Sun Shin, Jeong-Hun Yoo, Hun Jun Lim, Jun Lee, and Bong Chul Kim. "Anatomical Characteristics of the Masseter Muscle in Mandibular Prognathism." Applied Sciences 11, no. 10 (May 13, 2021): 4444. http://dx.doi.org/10.3390/app11104444.

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Mandibular prognathism causes functional and esthetic problems. Therefore, many studies have been conducted to understand its etiology. Following our previous study, which revealed that the major characteristic of the mandible with prognathism is the volume/length ratio of the mandibular body and condyle, we analyzed the volume and orientation of the masseter muscle, which inserts into the mandibular body, expecting that the difference in the size of the masseter muscle causes the difference in the mandibular size. This study compared the masseter muscle of the participants in the prognathic group to those in the normal group on the volume/length ratio and orientation. The masseter muscle ratios (volume/length); the angle between the superficial and deep head of the masseter muscle; and the three planes (the palatal, occlusal, and mandibular) were analyzed. A total of 30 participants constituted the normal group (male: 15, female: 15) and 30 patients, the prognathic group (male: 15, female: 15). The results showed that the volume/length ratio of the masseter of the normal group was greater than that of the prognathic group (p < 0.05). In addition, the orientation of both the superficial and deep head of the masseter of the participants in the normal group was more vertical with respect to the mandibular plane than that of the prognathic group (p < 0.05). We concluded that the mechanical disadvantage of the masseter muscle of the prognathic group is attributed to mandibular prognathism.

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Eshghpour, Majid, and Seyed Amir Danesh-Sani. "Electromyographic Analysis of Masseter Muscle after Surgical Correction of Mandibular Prognathism." International Journal of Head and Neck Surgery 3, no. 3 (2012): 121–24. http://dx.doi.org/10.5005/jp-journals-10001-1110.

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ABSTRACT Sagittal split ramus osteotomy (SSRO) is commonly used for treatment of mandibular prognathism. This study evaluated masseter muscle activity using electromyography device, in patients with mandibular prognathism before and after bilateral SSRO of the mandible. Twelve prognathic patients (five males and seven females; mean age 20.6 years) were examined. Initial phase of orthodontic treatment was completed in all included patients. Electromyographic activity of masseter muscle was recorded during maximum voluntary clenching as follows: First evaluation: 7 days prior to surgery, second evaluation: 3 months after surgery and third evaluation: 6 months after surgery. Electro-myography quantities were significantly decreased 3 months after surgery. Electromyographic activity of masseter muscle was recovered to the preoperative level 6 months after bilateral SSRO of the mandible. SSRO of the mandible is a safe technique for correction of mandibular prognathism and not seriously affects masticatory muscle electromyographic activity. How to cite this article Eshghpour M, Danesh Sani SA. Electromyographic Analysis of Masseter Muscle after Surgical Correction of Mandibular Prognathism. Int J Head and Neck Surg 2012;3(3):121-124.

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Jawalekar, Rashmi, Pushpa Hazare, Ranjit H. Kamble, and Vikrant V. Jadhav. "Correlation of Angle SNA to Angle NSAR in Normal Occlusion, Class II Division I and Class III Malocclusion in Vidarbha Region - A Cephalometric Study." Journal of Evolution of Medical and Dental Sciences 10, no. 32 (August 9, 2021): 2543–47. http://dx.doi.org/10.14260/jemds/2021/522.

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BACKGROUND Facial prognathism may be because of prognathic maxilla, prognathic mandible or aggregate of both. Numerous studies performed to diagnose a single morphological feature commonly producing protrusive relationship, revealed that ‘a single morphological feature does not ordinarily produce a protrusive relationship. Existence of structural imbalance in one area also affects the nature of balance in other areas. A number of separate but inter-related cause and effect factors tend to augment each other in a cumulative and composite manner. Effect of marked discrepancy of an individual’s facial part could be cancelled or nullified by deviation of another part in opposite direction, ultimately resulting in good facial harmony. In this study by means of cephalometric roentgenography, the relation between Angle SNA and Angle NSAr was assessed in Vidharbhites, having normal occlusion, Class II division I and class III malocclusion. METHODS 40 individuals of normal occlusion, Class II division I and Class III Malocclusion, each between 16 and 25 years were analysed. These subjects were selected from patients reporting the outpatient department of Government Dental College, Nagpur. Statistically correlation between angles SNA and NSAr at level of significance 5 % was assessed. RESULTS After data collection a thorough observation & analysis was done and co-relation coefficient between SNA angle & NSAr (F--1.054 M--0.7981), also standard deviation of angular cephalometric measurement between males & females was found out in the population, leading to discussion on topic ‘Facial prognathism is due to maxillary prognathism, mandibular prognathism or combination of both’. In Females SNA was found to be 81 - 800 1.91310 and in males SNA was 82.1660 4. 380 respectively. CONCLUSIONS The results inferred that “Marked part of variation in Angle SNA can be explained by variation in Angle NSAr. KEY WORDS Angle SNA, Angle NSAr, Correlation

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Rosli, Norlihayana, Anis Farhan Kamaruddin, and Noor Ayuni Ahmad Shafiai. "EPIDEMIOLOGY AND GENETIC ASPECT OF NON-SYNDROMIC MANDIBULAR PROGNATHISM: A LITERATURE REVIEW." Journal of Health and Translational Medicine sp2023, no. 1 (June 6, 2023): 235–39. http://dx.doi.org/10.22452/jummec.sp2023no1.24.

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Mandibular prognathism is a Class III skeletal base manifestation in which the lower jaw overgrows with or without the upper jaw undergrowing, causing the lower jaw to appear more prominent than the latter. This manifestation results in an unattractive facial profile, misaligned bite, and hampered speech. Several reports suggested that the prevalence rate of mandibular prognathism varies depending on the demographic, and its primary aetiology is genetics. This literature review summarises the prevalence rate of mandibular prognathism in various populations, its inheritance pattern in different pedigree groups, and the loci and candidate genes involved in non-syndromic mandibular prognathism. Most studies show no relationship between gender and phenotypic prevalence, with Caucasians having the lowest prevalence of mandibular prognathism and East Asians having the greatest. The inheritance pattern of mandibular prognathism is diverse, with the most typical inheritance pattern being the dominant trait with incomplete penetrance. Genetic findings from many documented reports suggest that there may be more than a single gene that causes mandibular prognathism. Through genome-wide linkage analyses, several possible chromosomal loci and various candidate genes have been discovered, particularly in patients from the Chinese (FGF12, ADAMTS1, TGFB3, LTBP2, and COL2A1), Japanese (PLXNA2 and SSX2IP), and Korean (Matrilin-1) populations. It was discovered that the majority of the locus variations and candidate genes were expressed during the development of the mandible, which may cause mandibular prognathism.

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Zelken, Jonathan A., and Steven P. Davison. "Postmaxillectomy Prognathism." Plastic and Reconstructive Surgery 123, no. 2 (February 2009): 69e—71e. http://dx.doi.org/10.1097/prs.0b013e318196bba8.

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Parker, Michael G., James A. Lehman, and David E. Martin. "Mandibular Prognathism." Clinics in Plastic Surgery 16, no. 4 (October 1989): 677–85. http://dx.doi.org/10.1016/s0094-1298(20)31290-6.

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Cutovic, Tatjana, Jasna Pavlovic, and Ruzica Kozomara. "Analysis of dimensions of sella turcica in patients with mandibular prognathism." Vojnosanitetski pregled 65, no. 6 (2008): 456–61. http://dx.doi.org/10.2298/vsp0806456c.

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Introduction/Aim. Patients with mandibular prognathism as dominant symptom have disordered sagittal interjaw relations that make prominent appearance to this dental craniofacial anomaly beside hyperplastic mandibles and inverted front teeth overlap. The aim of this study was to examine the differences in dimensions of sella turcica in patients with mandibular prognathism and in eugnathic. Methods. On profile teleradiographs of 30 eugnathic control and 30 patients with mandibular prognathism, three parameters, which represent dimensions of sella turcica, were measured (surface, width and depth). Results. Statistically significant difference in values between the groups was found. All the three measured parameters were significantly higher in the patients with mandibular prognathism (p < 0.01). Conclusion. In the patients with mandibular prognathism all the measured dimensions of sella turcica were bigger, and so was sella turcica, but that enlargement was not in correlation with the degree of anomaly itself.

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Lee, April, and Chris Yang. "Familial aggregation of mandibular prognathism." Dentistry 3000 3, no. 1 (April 8, 2015): 13–15. http://dx.doi.org/10.5195/d3000.2015.32.

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Mandibular prognathism is a hereditary condition where there is an excess growth of the mandible in relation to the maxilla that can be associated with maxillary retrusion, mandibular protrusion, or both. Skeletal mandibular prognathism is most prevalent in Eastern Asian populations. This paper focuses on a Korean family with skeletal mandibular prognathism that was inherited through three generations. Apparently, neither mandible nor maxilla is retruded in the affected individuals, but there is a concave facial profile. The dentition has a class I occlusion with skeletal mandibular prognathism, and the only way to treat this case would be orthognathic surgery with the help of orthodontic appliances.

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Stojanovic, Zdenka, Predrag Nikolic, Angelina Nikodijevic, Jasmina Milic, and Milos Duka. "Analysis of variation of sagittal position of the jaw bones in skeletal class III malocclusion." Vojnosanitetski pregled 69, no. 12 (2012): 1039–45. http://dx.doi.org/10.2298/vsp1212039s.

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Background/Aim. Skeletal Class III malocclusion is a discrepancy in the sagittal jaw relationship, due to imbalances in their development and/or position, resulting in the dominant appearance of the lower jaw in facial profile. The aim of this study was to determine variations in the sagittal position of the jaw bones to the cranial base in subjects with skeletal Class III, for the earliest possible diagnosis of malocclusion. Methods. Fifty children and as many adults with skeletal Class III, both sexes, were examined and selected, based on the findings of sagittal interjaw relationship (ANB) ? 0? from the cephalometric analysis of tele-x-ray profile head shots. The subjects were grouped according to age. The first group consisted of children aged 6-12 years, and another group, of adults aged 18-26 years. We measured the angles of maxillary prognathism (SNA), mandibular prognathism (SNB) and ANB. Based on these results, within the respective groups subclassification into the subgroups was done, among which a significant difference measured values was evaluated. In both groups a significant correlation of the determined values was evaluated. Results. An average SNA angle ranged 77.36 ? 3.58 in children and 77.32 ? 4.88 in adults, while an average SNB angle was 79.46 ? 3.91 in the group of children and 81.12 ? 3.76 in adults. An average ANB angle was -2.10 ? 2.07 in children, and -4.00 ? 2.34 in adults. In both groups, a significant correlation between the measured values and a significant difference in the values of all the measured parameters were found between patients from different subgroups (p < 0.01). Conclusion. The most common morphological variation of sagittal position of the upper jaw is its retrognatism, which is equally present in both children and adults. Sagittal position of the lower jaw in most of the adults was prognathic, while mandible prognathism in the children was less present.

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Cutovic, Tatjana, Nebojsa Jovic, Ruzica Kozomara, Julija Radojcic, Mirjana Janosevic, Irena Mladenovic, and Stevo Matijevic. "Cephalometric analysis of the middle part of the face in patients with mandibular prognathism." Vojnosanitetski pregled 71, no. 11 (2014): 1026–33. http://dx.doi.org/10.2298/vsp1411026c.

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Background/Aim. The middle part of the face, that is the maxilla, has always been mentioned as a possible etiologic factor of skeletal Class III. However, the importance of the relationship of maxillary retroposition towards the cranial base is still unclear, although it has been examined many times. The aim of this study was to conduct cephalometric analysis of the morphology of maxilla, including the whole middle part of the face in patients with divergent and convergent facial types of mandibular prognathism, as well as to determine differences betweeen them. Methods. Lateral cephalometric teleradiograph images of 90 patients were analyzed at the Dental Clinic of the Military Medical Academy, Belgrade, Serbia. All the patients were male, aged 18-35 years, not previously treated orthodontically. On the basis of dentalskeletal relations of jaws and teeth, the patients were divided into three groups: the group P1 (patients with divergent facial type of mandibular prognathism), P2 (patients with convergent facial type of mandibular pragmathism) and the group E (control group or eugnathic patients). A total of 9 cephalometric parameters related to the middle face were measured and analyzed: the length of the hard palate - SnaSnp, the length of the maxillary corpus - AptmPP, the length of the soft palate, the angle between the hard and soft palate - SnaSnpUt, the angle of inclination of the maxillary alveolar process, the angle of inclination of the upper front teeth, the effective maxillary length - CoA, the posterior maxillary alveolar hyperplasia - U6PP and the angle of maxillary prognathism. Results. The obtained results showed that the CoA, AptmPP and SnaSnp were significally shorter in patients with divergent facial type of mandibular prognathism compared to patients with convergent facial type of the mandibular prognathism and also in both experimental groups of patients compared to the control group. SnaSnp was significantly shorter in patients with divergent facial type of mandibular prognathism compared to the control group, whereas SnaSnp was significantly smaller in patients with convergent facial type of mandibular prognathism compared to the control group. Additionally, there was a pronounced incisor dentoalveolar compensation of skeletal discrepancy in both groups of patients with mandibular prognathism manifested in the form of a significant upper front teeth protrusion, but without significant differences among the groups, while the maxillary retrognathism was present in most patients of both experimental groups. A pronounced UGPP was found only in the patients with divergent type of mandibular prognathism. Conclusion. The maxilla is certainly one of the key factors which contributes to making the diagnosis, but primarily to making a plan for mandibular prognathism treatment. Accurate assessment of the manifestation of abnormality, localization of skeletal problems and understanding of the biological potential are key factors of the stability of the results of surgical-orthodontic treatment of this abnormality.

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Gharnizadeh, Kamal, Alireza Mohammadi, Zahra Malekpoor, and Maryam Sohrabi. "Correction of Mandibular Prognathism by Orthognathic Surgery in a Patient with Acromegaly." Galen Medical Journal 2, no. 1 (March 31, 2013): 32–34. http://dx.doi.org/10.31661/gmj.v2i1.52.

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Background: Acromegaly, a condition which is associated with an acquired progressive disfigurement mainly involving the face and extremities, is a clinical syndrome which results from excessive production of growth hormone (GH) most commonly due to adenoma of the pituitary gland. Acromegaly is a rare disease which due to its slow progression, is mostly diagnosed in late adulthood. Bilateral symmetrical prognathic mandible is considered as a diagnostic symptom of acromegaly. Nowadays, orthognathic surgery is done for treatment of this skeletal deformity; however, because of its relapse after surgery, the efficacy of this procedure remains uncertain.Case report: In this report we present a 33 years old man who was admitted for correction of Prognathism resulted from acromegaly in Bou-Ali Hospital. Class III skeletal growth form was achieved in his cephalometry analysis. Macroglossia, concave profile with prominent supra orbital ridges, prognathism, large lips and bulbous nose were detected in his physical examination. Orthognathic surgery as well as median glossectomy was performed and after 1 year follow up no recurrence was detected.Conclusion: It is assumed that keeping GH in a normal range before the surgery and also evaluation of orthognathic aspect and endocrine status of the patient in the follow ups are effective in preservation of orthognathic surgery outcomes.

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Mathapun, Jirath, and Chairat Charoemratrote. "Is Incisor Compensation Related to Skeletal Discrepancies in Skeletal Class III? A Retrospective Cephalometric Study." Diagnostics 14, no. 10 (May 15, 2024): 1021. http://dx.doi.org/10.3390/diagnostics14101021.

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This study investigated compensation in skeletal Class III subjects to compare various severities of abnormal jaws. A retrospective analysis of 137 skeletal Class III cephalograms (63 males and 74 females) was conducted, with cephalometric assessments determining skeletal and dental values. The results were compared with Class I cephalograms. Incisor compensation was examined by pairing normal jaws with varied abnormal jaws, classified by severity using one standard deviation (SD). Statistical analyses included Kruskal–Wallis tests, Bonferroni tests, Spearman’s correlations, and multiple linear regression. Four skeletal Class III groups were identified: OMx+PMd, RMx+OMd, OMx+OMd, and PMx+PMd (P = prognathic; O = orthognathic; R = retrognathic; Mx = maxilla; Md = mandible.). The upper central incisor (U1) showed proclination, and the lower central incisor (L1) showed retroclination across all groups except for U1 in PMx+PMd and L1 in OMx+OMd, which exhibited normal inclination. U1 exhibited limited compensation even with progressive maxillary retrognathism, while L1 showed limited compensation after one SD of mandibular prognathism. Maxilla (SNA) and jaw discrepancy (ANB) were inversely related to the U1 degree, whereas only jaw discrepancy (ANB) was positively related to the L1 degree. U1 in PMx+PMd and L1 in OMx+OMd showed no incisor compensation. U1 had limited compensation even with progressive maxillary retrognathism while L1 showed limited compensation after one SD mandibular prognathism.

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Cutovic, Tatjana, Jana Ilic, Tijana Adamovic, Stevo Matijevic, Julija Radojicic, and Srboljub Stosic. "Dental and skeletal changes occurring after orthodontic-surgical treatment of mandibular prognathism." Vojnosanitetski pregled, no. 00 (2022): 35. http://dx.doi.org/10.2298/vsp220202035c.

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Background/Aim: Mandibular prognathism is a severe form of facial and jaw deformity. Treatment of this anomaly usually requires combined orthodontic-surgical therapy. The aim of this study is to determine the changes in the craniofacial complex after orthodonticsurgical treatment of patients with mandibular prognathism by analyzing the cephalometric parameters on teleradiography images before and after treatment. Methods: The study included a sample of 40 patients (mean age 24.1 ? 4.10) who underwent orthodonticsurgical treatment of mandibular prognathism. Vertical and sagittal parameters characterizing mandibular prognathism were measured on profile teleradiography images before treatment and 12 months after treatment. Based on the analysis of cephalometric parameters on preoperative and postoperative teleradiography images, dental and skeletal changes that occurred after treatment were determined. Results: After the end of the treatment, all the parameters that characterize mandibular prognathism were significantly reduced. A drop in parameters was noted like the following: SNB, SNPg, NS/SpP, NS/MP, SpP/MP (<B), NSAr, ArGoMe, Bjork polygon, NMe, NSna, SnaMe, SSnp, I/SpP. There was a statistically significant increase in parameters: SNA, ANB, GoArNS, SGo, and i/MP. No statistically significant changes in values were recorded on the OP/NS and SArGo parameters. Conclusion: Orthodontic-surgical treatment leads to changes in the bone and dental structures of the craniofacial system. As a result of such treatment, there is a functional improvement and an improvement in the appearance of the face.

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Kantaputra, Piranit N., Apitchaya Pruksametanan, Nattapol Phondee, Athiwat Hutsadaloi, Worrachet Intachai, Katsushig Kawasaki, Atsushi Ohazama, et al. "ADAMTSL1 and mandibular prognathism." Clinical Genetics 95, no. 4 (March 18, 2019): 507–15. http://dx.doi.org/10.1111/cge.13519.

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Chang, Hong-Po, Yu-Chuan Tseng, and Hsin-Fu Chang. "Treatment of Mandibular Prognathism." Journal of the Formosan Medical Association 105, no. 10 (2006): 781–90. http://dx.doi.org/10.1016/s0929-6646(09)60264-3.

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Deveragunda Somappa, P., and I. Vasiluta. "Maxillary prognathism – dentoalveolar osteotomy." International Journal of Oral and Maxillofacial Surgery 36, no. 11 (November 2007): 1092. http://dx.doi.org/10.1016/j.ijom.2007.09.044.

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Cutovic, Tatjana, Nebojsa Jovic, Ljiljana Stojanovic, Julija Radojicic, Irena Mladenovic, Stevo Matijevic, and Ruzica Kozomara. "A cephalometric analysis of the cranial base and frontal part of the face in patients with mandibular prognathism." Vojnosanitetski pregled 71, no. 6 (2014): 534–41. http://dx.doi.org/10.2298/vsp121212011c.

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Bacground/Aim. The literature suggests different views on the correlation between the cranial base morphology and size and saggital intermaxillary relationships. The aim of this study was to investigate the cranial base morphology, including the frontal facial part in patients with mandibular prognathism, to clarify a certain ambiguities, in opposing viewspoints in the literature. Methods. Cephalometric radiographies of 60 patients were analyzed at the Dental Clinic of the Military Medical Academy, Belgrade, Serbia. All the patients were male, aged 18-35 years, with no previous orthodontic treatment. On the basis of dental and sceletal relations of jaws and teeth, the patients were divided into two groups: the group P (patients with mandibular prognathism) and the group E (the control group or eugnathic patients). A total of 15 cephalometric parametres related to the cranial base, frontal part of the face and sagittal intermaxillary relationships were measured and analyzed. Results. The results show that cranial base dimensions and the angle do not play a significant role in the development of mandibular prognathism. Interrelationship analysis indicated a statistically significant negative correlation between the cranial base angle (NSAr) and the angles of maxillary (SNA) and mandibular (SNB) prognathism, as well as a positive correlation between the angle of inclination of the ramus to the cranial base (GoArNS) and the angle of sagittal intermaxillary relationships (ANB). Sella turcica dimensions, its width and depth, as well as the nasal bone length were significantly increased in the patients with mandibular prognathism, while the other analyzed frontal part dimensions of the face were not changed by the malocclusion in comparison with the eugnathic patients. Conclusion. This study shows that the impact of the cranial base and the frontal part of the face on the development of profile in patients with mandibular prognathism is much smaller, but certainly more complex, so that morphogenetic tests of the maxillomandibular complex should be included in further assessment of this impact.

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Vukicevic, Vladanka, and Djordje Petrovic. "Relationship between head posture and parameters of sagittal position and length of jaws." Medical review 69, no. 9-10 (2016): 288–93. http://dx.doi.org/10.2298/mpns1610288v.

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Introduction. Head posture in relation to the cervical spine is correlated with the morphology of the face and jaw, the position and the mutual relationship of the maxilla and mandible, their length and inclination. The aim of this study is to examine the relationship between the head posture and parameters of the sagittal position and length of the jaws. Material and Methods. The study included 90 subjects (30 for I, II and II skeletal class each) between the ages of 8 and 14 years, who were examined at the Department of Dentistry of Vojvodina in Novi Sad. Each subject had the lateral cephalogram made, and the analysis was performed by means of the computer program ?Onyx Ceph.? The following parameters were analyzed: craniocervical angle, angle of maxillary prognathism, angle of mandibulary prognathism, the difference angles of maxillary and mandibulary prognathism, length of maxillae, and length of mandible. Results. The angle of maxillary prognathism was in positive correlation with the craniocervical angle in the patients with class I and II, and they were negatively correlated in the patients with class III. The angle of mandibulary prognathism was in positive correlation with the craniocervical angle in the patients with class I and III, but they were negatively correlated in the patients with class II. The patients with class II had a statistically significant positive correlation between the craniocervical angle and length of the maxilla, and a significant, but negative correlation between the craniocervical angle and length of the mandible. Conclusion. Increased extension of the head in relation to the cervical spine can be a contributing factor to the formation of class II malocclusion.

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Azhar Ibrahim Kharsa, Mhd. "BCP “Bilateral Cleft Palate” Appliance." Journal of Clinical Research and Reports 15, no. 3 (April 11, 2024): 01–04. http://dx.doi.org/10.31579/2690-1919/359.

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In this article, the authors are trying to describe an approach for treating the “bilateral cleft palate” newborn patients, by a simple removable appliance, BCP “Bilateral Cleft Palate” Appliance. The appliance is a removable acrylic plane, with Y shaped three sectors, an expander “works as an intraoral retractor to retract the prognathism” and a “filament” or string for appliance withdrawal and removal when required. This appliance is indicated for newborn bilateral cleft palate patients, especially during the first days of extra uterus life when infant patient suffers difficulties in nursing and feeding because of the cleft palate effects, nasopalatine fistula, and when requirements are existed to retract the anteriorly protruded prognathism, as well. The action of this appliance is orthopedic as it works to retract the prognathism by activation of the “opened central expander” that works herein as in fact a “retractor and contractor”.

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Ilic, Jana, Tatjana Cutovic, Ruzica Kozomara, Julija Radojicic, Tijana Adamovic, and Jovana Lovric. "Assessment of the impact of orthodontic-surgical treatment on the quality of life of patients with mandibular prognathism." Vojnosanitetski pregled, no. 00 (2022): 63. http://dx.doi.org/10.2298/vsp220512063i.

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Background/Aim. Mandibular prognathism as one of the more severe forms of dentofacial deformities impairs the oral functions and appearance of the patient's face and represents a psychosocial handicap with a negative impact on their quality of life. This study aims was to assess the impact of orthodontic-surgical treatment on the quality of life of patients with mandibular prognathism. Methods. The study involved 40 patients (19 men and 21 women, mean age 24.1 ? 4.10) who underwent orthodontic-surgical treatment of mandibular prognathism. All patients completed two questionnaires, the Oral Health Impact Profile (OHIP-14) and the Orthognathic Quality of Life Questionnaire (OQLQ), before the start of treatment and 12 months after the completion of treatment. Results. Both questionnaires showed an improvement in the quality of life compared to the condition before the start of treatment. According to the OQLQ questionnaire, there was a postoperative improvement in quality of life (M = 24.83 ? 12.99) compared to the preoperative period (M = 51.28 ? 15.2). According to the OHIP questionnaire, there was a postoperative improvement in quality of life (M = 11.34 ? 2.99) compared to the preoperative period (M = 20.8 ? 6.88). The improvement of quality of life 12 months after treatment occurred in all segments measured by both questionnaires. Conclusion. Orthodontic-surgical treatment of mandibular prognathism improves all oral functions, the appearance of the patient's face, and thus improves the quality of life.

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Kurokawa, Makoto, Hiroyuki Kanzaki, Hajime Tokiwa, Hideho Handa, Kazutoshi Nakaoka, Yoshiki Hamada, Hitoshi Kato, and Yoshiki Nakamura. "The main occluding area in normal occlusion and mandibular prognathism." Angle Orthodontist 86, no. 1 (April 15, 2015): 87–93. http://dx.doi.org/10.2319/111114-807.1.

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ABSTRACT Objective: To clarify whether the concept of main occluding area, where hard food is initially crushed, exists in patients who have a jaw deformity. Materials and Methods: Nineteen subjects with normal occlusion, 18 patients with mandibular prognathism, and 11 patients with mandibular prognathism who had undergone orthognathic surgery participated in this study. The main occluding area was identified by clenching Temporary Stopping. The coincidence, location of the main occluding area, and distance from the first molars to main occluding area were examined. Results: High coincidence of the main occluding area was obtained in all groups, signifying that the main occluding area exists even in these patients. Mandibular main occluding area was located on the first molar in all groups. Maxillary main occluding area in subjects with normal occlusion was located on the first molar. However, it was located on the second premolar and first molar in patients with mandibular prognathism, and on the first and second molars in patients with mandibular prognathism who had undergone orthognathic surgery. There was a statistically significant difference in distance from the maxillary first molar to the main occluding area among groups, but there was no difference in the distance from the mandibular first molar among groups. Conclusion: The main occluding area is more stable on the mandibular first molar than the maxilla in all groups.

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Mahjoubi, F., M. Akbary, and Y. Shafegatee. "XYY Karyotype in a Mentally Retarded Man with Prognathism and Malformation of His Hands and Toe Nails." Balkan Journal of Medical Genetics 13, no. 2 (January 1, 2010): 71–73. http://dx.doi.org/10.2478/v10034-010-0030-8.

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XYY Karyotype in a Mentally Retarded Man with Prognathism and Malformation of His Hands and Toe NailsWe report on a 25-year-old man who was referred for evaluation of possible Fragile X syndrome on the basis of mild mental retardation and malformation of his hands and toe nails. He was found not to have this syndrome but to have a 47, XYY karyotype. Only one other case of XYY syndrome with prognathism and malformation of hands has been reported.

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Shetty, Rajmohan, Joseph M. John, Amitha M. Hegde, and Amina Usman. "R.M.S. bite corrector: A novel appliance for the correction of mandibular prognathism in growing children-Part one: Skeletal and dental changes." Biomedicine 42, no. 5 (November 14, 2022): 949–55. http://dx.doi.org/10.51248/.v42i5.1640.

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Introduction and Aim: Mandibular prognathism is one of the most challenging conditions in clinical dental practice. No appliance has yet been introduced to manage this strenuous condition. Hence, a modified appliance, R.M.S. (removable acrylic splint) bite corrector was fabricated combining the principles of three conventional appliances. The aim was to evaluate the skeletal and dental changes following R.M.S bite corrector in growing children with mandibular prognathism, using lateral cephalograms. Materials and Methods: Twenty children between the age group 9 - 13 years, presenting with class III malocclusion with prognathic mandible were selected. R.M.S bite corrector was fabricated, which consist of reverse twin block with RME (Rapid Maxillary Expansion) incorporated in the upper block. Hooks integrated in the molar region of the upper block, and between the lateral incisors and canines in the lower block. A gradual increasing force was delivered by engaging intraoral intermaxillary elastics. After 10 months, skeletal, dental, and dentoalveolar parameters and linear measurements of jaw bases were compared using pre- and post-operative lateral cephalograms. Results: After 10 months, skeletal changes included a significant retrusion of the mandible and maxillary protraction. Dental changes comprised of an increase in proclination of maxillary and mandibular incisors, which was not significant. A significant increase in the length of the maxillary base, non-significant change in the linear measurements of the mandibular base and ramal length leading to relocation of the mandible in a relatively new position with better esthetics. Conclusion: Desirable skeletal and dental changes were observed following R.M.S. bite correction.

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Tornes, Knut, and Torstein Lyberg. "Surgically treated for mandibular prognathism." Acta Odontologica Scandinavica 45, no. 2 (January 1987): 95–100. http://dx.doi.org/10.3109/00016358709098363.

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Chandrasekaran, Jagadeesh, Manjunatha Gajanana Hegde, and Boochandran TS. "Unraveling the Amyloid and Acromegaly Dilemma: A Challenging Case Report." International Journal of Health Sciences and Research 13, no. 7 (July 4, 2023): 162–66. http://dx.doi.org/10.52403/ijhsr.20230723.

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Systemic amyloidosis encompasses a range of conditions caused by various factors, characterized by the production and abnormal accumulation of misfolded proteins outside cells in different organs, leading to tissue damage. Due to the varied and non-specific symptoms associated with the disease, diagnosing this condition is often delayed. The predominant types of this condition include light chain (AL) amyloidosis, Amyloid A (AA), and transthyretin-related ATTR amyloidosis. We present a case report of a 61-year-old gentleman who presented with progressive enlargement of the tongue and prognathism mimicking acromegaly. Key words: Amyloidosis, Acromegaly, Prognathism, Plasma Cell Disorders

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Premkumar, Sridhar, and Bhuvaneswari Gurumurthy. "Assessment of 2D:4D in Subjects with Anteroposterior Mandibular Dysplasia." Journal of Contemporary Dental Practice 14, no. 4 (2013): 582–85. http://dx.doi.org/10.5005/jp-journals-10024-1367.

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ABSTRACT Objectives To compare 2D:4D ratio which is determined by testosterone levels with patients having orthognathic, retrognathic and prognathic mandibles. Materials and methods The study was performed at Chennai, on 320 subjects of which, 60 subjects (32 males and 28 females) had retrognathic mandible; 55 subjects (25 males and 30 females) had prognathic mandible and 205 subjects (98 males and 107 females) had normal mandible. All the subjects had a normal maxilla and were in the age group of 18 to 25 years. 2D:4D ratio was determined using the photocopies of the ventral surface of right hand made with vernier calipers of 0.01 mm accuracy. Statistical analysis was undertaken using Student's t- test, ANOVA test and TukeyHSD test. Results (i) Low 2D:4D is seen in subjects with mandibular prognathism, (ii) Among females, low 2D:4D is seen only in prognathic mandible. Conclusion These findings highlight the fact that testosterone plays an important role in mandibular growth. Thus 2D:4D, a least invasive and reproducible procedure can be used as an early marker for mandibular progathism, and as a diagnostic tool in correlating the mandibular growth with causal relations between hormones and craniofacial development. How to cite this article Premkumar S, Gurumurthy B. Assessment of 2D:4D in Subjects with Anteroposterior Mandibular Dysplasia. J Contemp Dent Pract 2013;14(4):582-585.

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Kagawa, Haruka, Masato Kaku, Taeko Yamamoto, Yuka Yashima, Hiromi Sumi, Takashi Kamiya, Ichiro Yamamoto, and Kotaro Tanimoto. "Changes in tongue–palatal contact during swallowing in patients with skeletal mandibular prognathism after orthognathic surgery." PLOS ONE 16, no. 5 (May 19, 2021): e0251759. http://dx.doi.org/10.1371/journal.pone.0251759.

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This study aimed to evaluate improvement of tongue-palatal contact patterns during swallowing after orthognathic surgery in mandibular prognathism patients. Thirty patients with mandibular prognathism treated by orthognathic surgery (average age of 27 years, 3 months) and 10 controls (average age 29 years, 6 months) participated in this study. Tongue-palatal contact patterns of patients before and three months after surgery were evaluated by electropalatography (EPG) as well as controls. Whole total of tongue-palatal contact at 0.3, 0.2, and 0.1 sec before complete tongue-palatal contact during swallowing were evaluated. The duration of swallowing phases was also examined. Complete contact of tongue-tip in the alveolar part of individual artificial EPG plate were shown at 0.3, 0.2, and 0.1 sec before complete tongue-palatal contact in the controls, although incomplete contact in the alveolar part were shown at 0.3 sec in mandibular prognathism patients. Whole total of tongue-palatal contact at 0.3 and 0.2 sec before complete tongue-palatal contact was significantly lower in the patients before surgery than in the controls (p<0.05). However, these values increased after surgery. The duration of oral and pharyngeal phase was significantly longer in the patients before surgery than in the controls and the patients after surgery (p<0.01). This study demonstrated that the tongue-palatal contact pattern improved and the duration of oral and pharyngeal phase was shortened in mandibular prognathism patients during swallowing after orthognathic surgery. It is suggested that changes in maxillofacial morphology by orthognathic surgery can induce normal tongue movement during swallowing. (The data underlying this study have been uploaded to figshare and are accessible using the following DOI: https://doi.org/10.6084/m9.figshare.14101616.v1)

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Cutovic, Tatjana, Jasna Pavlovic, and Ruzica Kozomara. "Radiographic cephalometry analysis of dimensions of condylar processus in persons with mandibular prognathism." Vojnosanitetski pregled 65, no. 7 (2008): 513–19. http://dx.doi.org/10.2298/vsp0807513c.

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Introduction/Aim. There are numerous factors that influence the formation of condylar processus: the growth and development of cranial base, growth and development of the jaws and alveolar extensions, teething, the way of intercuspidation, the overlap of incisors, functions of masticatory muscles, etc. Considering the fact that the above-mentioned factors significantly differ in persons with different morphological set of the face, we set a hypothesis that dimensions of condylar processus and the mandibular ramus considerably differ in persons with mandibular prognathism compared to eugnatic persons. The aim of this study was to establish the differences in dimensions of condylar processus between the above-mentioned groups. Methods. Six parameters representing the dimensions of the condylar processus were measured on profile teleradiographs of 30 eugnatic persons and 30 paersons with mandibular prognathism: the height of condylar processus, the height of head of the mandible, width of the head, width of the neck, height of the ramus without the condylar processus and the overall height of the ramus. Results. A considerable difference in the values of the parameters was found, as well as the distribution toward the values of reference. It was found that the height of the condylar processus was significantly greater in persons with mandibular prognathism, whereas the width of the head of the mandible, the width of the neck and the height of the ramus without the condylar processus was considerably decreased within the same group. The height of the head of the mandible and the overall height of the ramus was not significantly changed. Conclusion. In persons with mandibular prognathism, morphological features of the condylar processus are changed. The condylar processus lengthens on account of shortening of the lower part of the ramus, and the mentioned lengthening is the most prominent in its condylar neck area which is also the centre of its most intense growth.

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Liu, Hanghang, Chenzhou Wu, Jie Lin, Jun Shao, Qianming Chen, and En Luo. "Genetic Etiology in Nonsyndromic Mandibular Prognathism." Journal of Craniofacial Surgery 28, no. 1 (January 2017): 161–69. http://dx.doi.org/10.1097/scs.0000000000003287.

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Doraczynska-Kowalik, Anna, Kamil H. Nelke, Wojciech Pawlak, Maria M. Sasiadek, and Hanna Gerber. "Genetic Factors Involved in Mandibular Prognathism." Journal of Craniofacial Surgery 28, no. 5 (July 2017): e422-e431. http://dx.doi.org/10.1097/scs.0000000000003627.

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Cho, H. J., and T. Nguyen. "A classification system of mandibular prognathism." Oral Surgery 1, no. 3 (August 2008): 125–34. http://dx.doi.org/10.1111/j.1752-248x.2008.00032.x.

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CHANG, H. P., P. H. LIU, Y. H. YANG, H. C. LIN, and C. H. CHANG. "Craniofacial morphometric analysis of mandibular prognathism." Journal of Oral Rehabilitation 33, no. 3 (March 2006): 183–93. http://dx.doi.org/10.1111/j.1365-2842.2005.01563.x.

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Shahine, Mohammed S., and Ibraheem M. Mwafey. "Esthetic and functional advantages of subapical anterior segmental maxillary osteotomy in treatment of dentofacial deformity." Egyptian Journal of Surgery 42, no. 2 (April 2023): 402–8. http://dx.doi.org/10.4103/ejs.ejs_68_23.

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Aim This study aims to investigate the effect of anterior segmental maxillary osteotomy in treatment of maxillary prognathism with good molars occlusion. Patients and methods This study includes 20 patients diagnosed with dentofacial deformities − maxillary prognathism visiting maxillofacial surgery outpatient clinic in Assiut University Hospitals during the period between January 2017 and December 2021. Results The common complications which occur is wound infection which occur in two (10%) cases, then postoperative relapse which occur in one (5%) case, palatal mucosal tear which occur in one (5%) case, and unfavorable nasolabial esthetic which occur in one (5%) case. Conclusion Anterior segmental maxillary osteotomy is a recommended treatment modality of choice in patients with maxillary and/or dentoalveolar protrusion.

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Hayashi, Yuki, Chie Tachiki, Taiki Morikawa, Yasuo Aihara, Satoru Matsunaga, Keisuke Sugahara, Akira Watanabe, Takakazu Kawamata, and Yasushi Nishii. "Three-Dimensional Analysis of the Cranial Base Structure in Patients with Facial Asymmetry." Diagnostics 14, no. 1 (December 22, 2023): 24. http://dx.doi.org/10.3390/diagnostics14010024.

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Facial asymmetry is often seen in patients with skeletal mandibular prognathism and is associated with deformities in the maxillofacial and head regions. The maxillofacial deviation is three-dimensional and affects not only the lateral deviation of the mandible and midface, but also the cranium. This study conducted a three-dimensional morphological evaluation of the cranial base morphology of patients with skeletal mandibular prognathism (ANB < 0°, Wits < 0 mm) with the aim of examining the relationship between deformities of the head region and facial asymmetry. Data obtained from computed tomography conducted during the initial examination of patients with and without skeletal mandibular prognathism with facial asymmetry were used. Differences in the position of structures present in the cranial base were measured, and the association between cranial deformities and mandibular deviation was assessed. The middle cranial base area and the lateral deviation of the mandibular fossa were significantly larger in patients with facial asymmetry compared to those without facial asymmetry. In addition, a correlation between the amount of mandibular deviation and the area of the anterior cranial base was identified in patients with significant cranial deformity (p = 0.012). Given the identified association between the structure of the head region and facial asymmetry, further studies are needed to determine the factors implicated in the growth process.

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Shetty, Akhil, and Jaffer Sadik. "Correlation between the cranial base, mandible, and hyoid bone in Class II skeletal individuals- A cephalometric study." IP Indian Journal of Orthodontics and Dentofacial Research 9, no. 2 (June 15, 2023): 106–11. http://dx.doi.org/10.18231/j.ijodr.2023.019.

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The aim of this study was to assess the relationship between the cranial base, mandible, and hyoid bone in Class II skeletal individuals. The retrospective study included lateral cephalograms of 40 Skeletal Class II subjects divided into maxillary prognathism (n=20) and mandibular retrognathism(n=20) based on Burstone’s N⊥A and N⊥B values. The angular measurements using 10 variables were used to determine the relationship between the cranial base, mandible, and hyoid bone in Class II subjects. Statistical analyses were performed using IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp. An Independent t-test was used to compare the two groups and a p-value less than 0.05 was considered statistically significant. Post-Hoc Bonferroni was applied to examine any changes among any two groups that were found to differ statistically. NSAr, C3HyD, SArHy, and NSHy angles were measured in both groups. NSAr and NSHy angles showed significance between the two groups of skeletal class II whose p-value <0.05 whereas C3HyD and SArHy angles did not show any significance. The condylar position was anterior in maxillary prognathism compared to mandibular retrognathism of Skeletal Class II. The hyoid bone was positioned forward and upward in maxillary prognathism individuals and downward and backward in mandibular retrognathism individuals belonging to skeletal class II.

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Miranda, Juan G. L., Mario D. G. Rodriguez, Obed H. G. Chavez, Eros R. R. Almeida, and Arianna R. Berrones. "Inverted flap lip plasty, Abbe's method, in the reconstruction of bilateral complete cleft lip sequelae: report of a case." International Surgery Journal 10, no. 10 (September 28, 2023): 1673–79. http://dx.doi.org/10.18203/2349-2902.isj20232993.

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This study presents the case of a female patient treated between the ages of 19 and 24 years, with sequelae of complete bilateral cleft lip and palate. Sequelae treated include upper lip incompetence due to low lip volume and length, absence of premaxilla (due to unknown cause), conditioning a large naso alveolar and naso palatal fistula in the region of the primary and secondary palate junction (Pittsburgh V), and finally, dental malocclusion due to prognathism condition. Aforementioned sequelae were treated through upper labial plasty at the expense of translocation of pedicled lower labial flap in the lower labial artery, using Abbe's method; upper anterior removable partial anterior dental prosthesis, with sealing of the nasal cavity, and finally, Intraoral bilateral sagittal split osteotomies of mandibular ascending ramus, in order to reduce prognathism.

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Reston, E. G., L. Q. Closs, A. L. S. Busato, G. A. Broliato, and F. R. Tessarollo. "Restoration of Occlusal Vertical Dimension in Dental Erosion Caused by Gastroesophageal Reflux: Case Report." Operative Dentistry 35, no. 1 (January 1, 2010): 125–29. http://dx.doi.org/10.2341/09-110t.

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PURPOSE The authors describe a minimally invasive procedure for occlusal rehabilitation in a young patient presenting with mild mandibular prognathism and loss of occlusal vertical dimension caused by dental erosion from chronic gastroesophageal reflux.

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Yamada, Chiaki, Noriyuki Kitai, Naoya Kakimoto, Shumei Murakami, Souhei Furukawa, and Kenji Takada. "Spatial Relationships between the Mandibular Central Incisor and Associated Alveolar Bone in Adults with Mandibular Prognathism." Angle Orthodontist 77, no. 5 (September 1, 2007): 766–72. http://dx.doi.org/10.2319/072906-309.

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Abstract Objective: To examine if there was any correlation between the labio-lingual inclinations of the mandibular central incisor and the associated alveolar bone, and to investigate the labio-lingual position of the mandibular central incisor root apex in the associated cancellous bone in adults with untreated mandibular prognathism. Materials and Methods: High-resolution computed tomography images of the mandible were recorded in 20 adult patients with mandibular prognathism. The labio-lingual inclinations of a central incisor and its associated alveolar bone, the thickness of the associated cancellous bone, and the distance from the central incisor root apex to the inner contour of both the labial and lingual cortical plates were measured. Correlations and differences between the measured variables were tested for statistical significance. Results: The labio-lingual inclination of the central incisor significantly correlated with the labio-lingual inclination of the associated alveolar bone, the thickness of cancellous bone, and the distance from the central incisor root apex to the inner contour of the lingual cortical bone. The distance from the central incisor root apex to the inner contour of the labial cortical plate of bone was significantly smaller than that to the lingual cortical plate. Conclusions: In adults with untreated mandibular prognathism, when the mandibular central incisor was more lingually inclined, the associated alveolar bone was also more lingually inclined and thinner. The mandibular central incisor root apex was closer to the inner contour of the labial cortical bone than to the lingual cortical bone.

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Ruslin, M., T. Forouzanfar, I. A. Astuti, E. S. Soemantri, and D. B. Tuinzing. "The anthropological aspects of dentofacial deformities: A comparison between Indonesian and Dutch cohorts (Aspek antropologi kelainan bentuk dentofasial: Sebuah perbandingan antara kelompok Indonesia dan Belanda)." Journal of Dentomaxillofacial Science 13, no. 1 (February 28, 2014): 48. http://dx.doi.org/10.15562/jdmfs.v13i1.387.

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The aim of the present study was to investigate the prevalence of dentofacial deformities in an Indonesian cohortcompared with a Dutch cohort and to study the anthropological aspects of dentofacial deformities. The Indonesiancohort included 36 male and 50 female patients from Bandung. The Dutch cohort included 1,003 male and 1,623female patients from Amsterdam. The majority of the Indonesian cohort was less than 30 years old (93%)comparedwith 61.5% of the Dutch cohort. The age distribution of 31-40 years consisted of more Dutch than Indonesian patients(p<0.01). Mandibular prognathism with an open bite was the most prevalent deformity (46.5%) among the Indonesiancohort with a mean age of 22.78 (SD;6.34). Mandibular deficiency was the least prevalent deformity (2.3%) with amean age of 31 (SD;12.73). In contrast, mandibular deficiency with a normal or low mandibular plane angle was themost prevalent deformity (55.9%)among the Dutch cohort with a mean age of 30.48 (SD;1075)and mandibularprognathism with an open bite was the least prevalent deformity (3.3%) with a mean age of 22.49 (SD;6.20). Comparedto the Dutch population, the Indonesian population consisted of more mandibular prognathism (p<0.01) and lessmandibular deficiency (p<0.01). In the Indonesian cohort, young patients seek orthognathic surgery most frequently tocorrect a functional problem associated with mandibular prognathism with an open bite. It was concluded that thegreatest severity of dentofacial deformities that are observed in Southeast Asian patients.

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Milosevic, Olga, Nadja Nikolic, Jelena Carkic, Nemanja Majstorovic, Branislav Glisic, and Jelena Milasin. "Analysis of COL1A1 and MMP9 single nucleotide polymorphisms in mandibular prognathism." Genetika 54, no. 2 (2022): 777–86. http://dx.doi.org/10.2298/gensr2202777m.

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Mandibular prognathism (MP) belongs to malocclusions of skeletal Class III and is characterized by overgrowth of the lower jaw with or without undergrowth of the upper jaw. MP etiology is multifactorial, including both environmental and genetic factors. It is conceivable that single nucleotide polymorphisms (SNPs) in genes controlling craniofacial development might contribute to MP. The aim of the present study was to establish a potential association between COL1A1 -1997 G>T (rs1107946) and MMP9 -1562 C>T (rs3918242) SNPs and MP in Serbian population. This case-control study included 120 participants: 60 patients with MP and 60 controls with skeletal Class I. The two SNPs were analyzed by means of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. The association of gene variants with MP risk was determined by calculating odds ratios (OR) and their 95% confidence intervals (CI).There was no difference in SNPs allele frequencies, and no difference could be observed in MMP9 -1562 C>T genotypes distribution between cases and controls. However, the TT genotype of COL1A1-1997 G/T (rs1107946) polymorphism was associated with a two-fold increase of mandibular prognathism risk, though with a borderline statistical significance (OR 2.32, CI 0.97-5.53, p=0.055). COL1A1-1997 G/T (rs1107946) appears to be implicated in Class III mandibular prognathism while MMP9 -1562 C/T (rs3918242) does not seem to be a risk factor for the development of this type of craniofacial anomaly.

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MATSUO, NAOKO, TOSHIYASU YAMASHITA, MASAMI KATO, MAKOTO ISOBE, KENJI YOSHIDA, YOSHIKI TAKAI, MASAHIKO FUKAYA, and HIROSHI INAMOTO. "The General Symptoms of Mandibular Prognathism Patients." Japanese Journal of Jaw Deformities 2, no. 1 (1992): 25–31. http://dx.doi.org/10.5927/jjjd1991.2.25.

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YOSHIDA, KENJI, NAOKO MATSUO, MICHIO KANEKO, and MASAHIKO FUKAYA. "The General Symtoms of Mandibular Prognathism Patients." Japanese Journal of Jaw Deformities 4, no. 1 (1994): 42–44. http://dx.doi.org/10.5927/jjjd1991.4.42.

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45

YASUMITSU, Chiaki, Toshihiro KIKUTA, and Nagayoshi YAMADA. "Questionnaire study after surgical correction of prognathism." Japanese Journal of Oral & Maxillofacial Surgery 35, no. 5 (1989): 1247–53. http://dx.doi.org/10.5794/jjoms.35.1247.

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46

Lundström, Fredrik, and Anders Lundström. "Clinical evaluation of maxillary and mandibular prognathism." European Journal of Orthodontics 11, no. 4 (November 1989): 408–13. http://dx.doi.org/10.1093/oxfordjournals.ejo.a036012.

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El-Gheriani, A. A., B. S. Maher, A. S. El-Gheriani, J. J. Sciote, F. A. Abu-shahba, R. Al-Azemi, and M. L. Marazita. "Segregation Analysis of Mandibular Prognathism in Libya." Journal of Dental Research 82, no. 7 (July 2003): 523–27. http://dx.doi.org/10.1177/154405910308200707.

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Manor, Yifat, Danielle Blinder, and Shlomo Taicher. "Sequence of Treatment in Mandibular Prognathism Patients." CRANIO® 24, no. 2 (April 2006): 95–97. http://dx.doi.org/10.1179/crn.2006.015.

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Guan, X., Y. Song, J. Ott, Y. Zhang, C. Li, T. Xin, Z. Li, et al. "TheADAMTS1Gene Is Associated with Familial Mandibular Prognathism." Journal of Dental Research 94, no. 9 (June 29, 2015): 1196–201. http://dx.doi.org/10.1177/0022034515589957.

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Bradley, J. P., H. K. Kawamoto, H. V. Katchikian, and R. Jarrahy. "O.390 Novel treatment for asymmetric prognathism." Journal of Cranio-Maxillofacial Surgery 36 (September 2008): S98. http://dx.doi.org/10.1016/s1010-5182(08)71514-2.

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