Добірка наукової літератури з теми "Pro-hemostatic agents"
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Статті в журналах з теми "Pro-hemostatic agents"
Laurenti, Juliana Bergamasco, Gabriel Zazeri, Ana Paula Ribeiro Povinelli, Moacir Fernandes de Godoy, Domingo Marcolino Braile, Tânia R. Flores da Rocha, Élbio Antônio D' Amico, and José Geraldo Nery. "Enhanced pro-coagulant hemostatic agents based on nanometric zeolites." Microporous and Mesoporous Materials 239 (February 2017): 263–71. http://dx.doi.org/10.1016/j.micromeso.2016.10.020.
Повний текст джерелаBudko, Elena V., Daria A. Chernikova, Leonid M. Yampolsky, and Valentina Y. Yatsyuk. "Local hemostatic agents and ways of their improvement." I.P. Pavlov Russian Medical Biological Herald 27, no. 2 (July 2, 2019): 274–85. http://dx.doi.org/10.23888/pavlovj2019272274-285.
Повний текст джерелаOtrocka-Domagała, I., P. Jastrzębski, Z. Adamiak, K. Paździor-Czapula, M. Gesek, M. Mikiewicz, and T. Rotkiewicz. "Safety of the long-term application of QuikClot Combat Gauze, ChitoGauze PRO and Celox Gauze in a femoral artery injury model in swine – a preliminary study." Polish Journal of Veterinary Sciences 19, no. 2 (June 1, 2016): 337–43. http://dx.doi.org/10.1515/pjvs-2016-0041.
Повний текст джерелаSchoenwaelder, Simone M., Kate E. Jarman, Elizabeth E. Gardiner, My Hua, Jianlin Qiao, Michael J. White, Emma C. Josefsson, et al. "Bcl-xL–inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets." Blood 118, no. 6 (August 11, 2011): 1663–74. http://dx.doi.org/10.1182/blood-2011-04-347849.
Повний текст джерелаAgraharkar, M., and M. A. Martinez. "Spontaneous Re-Canalization of Thrombosed Polytetrafluoroethylene (PTFE) Grafts." Journal of Vascular Access 2, no. 3 (July 2001): 114–18. http://dx.doi.org/10.1177/112972980100200306.
Повний текст джерелаSivakumar, Walavan, Jian Guan, Jean-Philippe Langevin, Neil A. Martin, Garni Barkhoudarian, Daniel F. Kelly, John Franklin Berry, and Aditya K. Iyer. "873 Code Brain Ultra-Early Clinical Pathway for Patient Identification and Management in Spontaneous Non-traumatic Intracranial Hemorrhage Single-Institution Study." Neurosurgery 70, Supplement_1 (April 2024): 173. http://dx.doi.org/10.1227/neu.0000000000002809_873.
Повний текст джерелаThalji, Nabil K., Lacramioara Ivanciu, Reema Jasuja, Sunita Patel-Hett, Joachim Fruebis, Debra Pittman, and Rodney M. Camire. "Zymogen-like FXa Is a Potent Bypassing Agent for Reversal of Direct FXa Inhibitors in Vivo." Blood 124, no. 21 (December 6, 2014): 582. http://dx.doi.org/10.1182/blood.v124.21.582.582.
Повний текст джерелаElbaz, Carolyne, Katerina Pavenski, Hina Chaudhry, Jerome M. Teitel, and Michelle Sholzberg. "The Frequency and Effect of Baseline Cross-Reacting and De Novo Inhibitors to Recombinant Porcine FVIII in Patients with Congenital and Acquired Hemophilia a." Blood 134, Supplement_1 (November 13, 2019): 1128. http://dx.doi.org/10.1182/blood-2019-122260.
Повний текст джерелаHartmann, Rudolf, Tjerk Feenstra, Sabine Knappe, Michael Dockal, and Friedrich Scheiflinger. "Elucidating the Excessive Pro-Coagulant Effect of a Sequence Identical Analogue to ACE910 in Combination with Bypassing Agents." Blood 130, Suppl_1 (December 7, 2017): 90. http://dx.doi.org/10.1182/blood.v130.suppl_1.90.90.
Повний текст джерелаJubelirer, Steven J. "Venous Thromboembolism and Malignant Brain Tumors: A Review." Clinical and Applied Thrombosis/Hemostasis 2, no. 2 (April 1996): 130–36. http://dx.doi.org/10.1177/107602969600200208.
Повний текст джерелаДисертації з теми "Pro-hemostatic agents"
Potzeha, Fanny. "Le potentiel thérapeutique des vésicules extracellulaires hémostatiques pour le traitement ciblé des hémorragies intracérébrales : de la production à grande échelle aux tests dans des modèles pré-cliniques." Electronic Thesis or Diss., Normandie, 2021. http://www.theses.fr/2021NORMC422.
Повний текст джерелаIntracerebral hemorrhage (ICH) is the most severe stroke subtype. Stopping the ongoingbleeding using pro-hemostatic agents is a promising therapeutic strategy that remains limitedby serious side effects such as uncontrolled thrombosis. In the present study, we developed anoriginal therapeutic strategy for ICH based on the administration of nanosized extracellularvesicles (EVs) that can trigger the coagulation cascade specifically at the site of active bleeding.We first generated large amounts of EVs from TNF-stimulated THP-1 monocytes in bioreactors.Those monocyte-EVs presented a mean size of around 300 nm, a high pro-hemostatic activityreducing the clotting time in a dose- and TF-dependent manner and a high expression of atargeting protein on their surface (P-Selectin Glycoprotein Ligand 1, PSGL-1). In preclinicalmodels of ICH in mice, intravenous injection of mEVs improved stroke outcome in a dosedependentmanner. mEVs at 1 mg/kg prevented hematoma growth by 43% and improvedneurological score at 24h compared to control mice (p<0.01, n=15/group). These effects werealso present in more severe models of ICH (enoxaparin or warfarin treated mice). Importantly,the beneficial effect was blocked when using antibodies blocking either TF or PSGL-1,suggesting that both the pro-coagulant activity and the ability to target damaged brain vesselsare mandatory for the therapeutic efficacy of EVs. To conclude, exogenous mEVs bearing TFand PSGL-1 improve outcome after collagenase-induced ICH by acting as intravascularhemostatic patches