Дисертації з теми "Preservative efficacy"
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Choong, Melissa Yen Ying. "Escherichia coli ATCC 8739 biosensor for preservative efficacy testing." Thesis, University of Hertfordshire, 2014. http://hdl.handle.net/2299/15623.
Повний текст джерелаBritz, Carel Marthinus. "Nevirapine in pro-Pheroid : a preservative efficacy and stability study / Carlie Britz." Thesis, North-West University, 2009. http://hdl.handle.net/10394/4752.
Повний текст джерелаThesis (M.Sc. (Pharmaceutics))--North-West University, Potchefstroom Campus, 2010.
Sheppard, Fiona Cathleen. "The application of rapid microbiological methods to preservative efficacy testing of pharmaceuticals." Thesis, King's College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243903.
Повний текст джерелаShah, Niksha Chimanlal Meghji. "Construction and development of bioluminescent Pseudomonas aeruginosa strains : application in biosensors for preservative efficacy testing." Thesis, University of Hertfordshire, 2014. http://hdl.handle.net/2299/15592.
Повний текст джерелаNayagam, S. "Studies on soluble nutrient components in wood and their influence on decay susceptibility and preservative efficacy." Thesis, University of Abertay Dundee, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376036.
Повний текст джерелаKelly, Anthony William. "The efficacy of boron-based preservatives in temperate and tropical timber species." Thesis, University of Portsmouth, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327771.
Повний текст джерелаGubler, Mitchell Miles. "Efficacy of socket grafting for alveolar ridge preservation: a randomized clinical trial." Thesis, University of Iowa, 2015. https://ir.uiowa.edu/etd/1848.
Повний текст джерелаMetcalfe, Matthew Stephen. "Warm perfusion of ischaemically damaged kidneys : ex-vivo function, viability assessment and preservation efficacy." Thesis, University of Leicester, 2003. http://hdl.handle.net/2381/29433.
Повний текст джерелаQuicho, Joemel Mariano. "Efficacy of Ultraviolet Light in Combination with Chemical Preservatives for the Reduction of Escherichia coli in Apple Cider." Thesis, Virginia Tech, 2005. http://hdl.handle.net/10919/33621.
Повний текст джерелаMaster of Science
Whitney, Brooke Meredith. "Efficacy of high pressure processing in combination with chemical preservatives for the reduction of Escherichia coli O157:H7 and Salmonella in apple juice and orange juice." Thesis, Virginia Tech, 2005. http://hdl.handle.net/10919/33853.
Повний текст джерелаMaster of Science
CHEN, CHIAU-RU, and 陳巧儒. "Antibacterial and Preservative Efficacy in Sailfish by Using Vacuum Package and Allyl Isothiocyanate." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/51602235457222057159.
Повний текст джерела國立高雄海洋科技大學
水產食品科學研究所
101
Histamine poisoning is usually associated with fishes such as tuna or sailfish. Because those fishes contain high levels of free histidine which can be converted by a decarboxylase produced by bacteria. Therefore, inhibiting the growth or enzymatic activities of histamine producing bacteria (HPB) is a critical procedure to prevent histamine poisoning. Japanese horseradish (wasabi) is a popular spice in Taiwan and its major volatile compound, allyl isothiocyanate (AIT), has been reported to possess a high antibacterial activity. Currently, vacuum-packing is the most common method to extend the shelf life of fishery products. However, a single preservation method such as applying AIT or vacuum packing is insufficient. The antibacterial and preservative efficacy of the combination of vacuum packaging and gaseous AIT in sailfish was evaluated. In the study, sailfish samples were inoculated with histamine producing bacteria, Raoultella ornithinolytica, then treated with different concentrations of gaseous AIT (329.08, 459.46 or 516.70 mg / L air) at 4°C for 24 hr. The sailfish samples were vacuum or non-vacuum packed, then stored at 15°C, 25°C or 4-25-4°C. The samples without vacuum package no AIT treatment were served as the control group. Levels of total aerobic counts, histamine-producing bacteria, total volatile basic nitrogen (TVBN) and biogenic amines were analyzed daily. Significantly lower counts of total aerobic and histamine producing bacteria was found in the AIT treated samples than the samples without AIT treatment (p<0.05) within the group without vacuum packaging. However, bacterial counts were not significantly reduced within the group with vacuum packaging. In addition, similar results were obtained for TVBN. TVBN values reduced correlated with the increasing AIT concentrations in the unvacuum packed group but not in the vacuum packed group. In the unvacuum packed group, histamine amount reduced significantly with AIT treatment (p<0.05) and the reduction is correlated with AIT concentrations. In the vacuum packed group, AIT treatment also showed an inhibitory effect against histamine production. Comparing the control, the vacuum packaged samples showed significantly lower histamine production than unvacuum packaged samples (p<0.05).
McKillop, Natasha. "Evaluating the Effect of Biodiesel on the Efficacy of the Wood Preservative Copper Naphthenate." Thesis, 2014. http://hdl.handle.net/10222/49102.
Повний текст джерелаSuwarno. "Efficacy of a Pediococcus sp. bacterial preparation for timothy hay preservation." 1993. http://hdl.handle.net/1993/18694.
Повний текст джерелаLai, Hsuan-Kang, and 賴軒康. "Preservation and efficacy of multiemulsified oral inactivated vaccine against grouper iridovirus." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/978z7r.
Повний текст джерела國立臺灣海洋大學
水產養殖學系
102
In this study, intends to investigate the effect of preservation and efficacy of multiemulsified oral inactivated vaccine against grouper iridovirus. Firstly experimental inactivated Grouper iridovirus (GIV) vaccines were prepared, after safety testing, stored at 4℃ and 25℃ room temperature for 8 months and 12 months, multie-mulsified vaccine are not occurring disintegrations. Further compared the efficacy with the new preparation vaccine protective, we had mix these five vaccines into fish feed and fed once every other week. Challenge with GIV at day 10 and day 20 post vaccination. The relative survival rate of the new preparation vaccine are 60% and 50%, of the vaccine preserved at 4 ℃ and 25 ℃ for 8 month are around 40 %, and of 4 ℃ and 25 ℃ for 12 month are decreased to 20%. Analyzed the anti GIV antibody titre in serum from each groups at day 1, 4, 7 post vaccination, the results which had compared with non-vaccinated control group indicated that antibody had stimulated in all the vaccinated fish. The antibody titre had slightly decreased at day 10, 14 post vaccination were observed in all the groups, especially the group fed with vaccine had preserved at 4 ℃ and 25 ℃ for 12 month. Finally, we analyzed the gene expression of MHC-I, TNF-α, IgM, Mx and INF-γ in spleen and head kidney. The results suggest that vaccinated groups were much higher than non-vaccinated groups, such as INF-γ in spleen. Mx gene expression has significant difference between new prepared vaccine and other preserved vaccines. All the results had suggested that the inactivated vaccine could be well preserved using multie- mulsified preperation, and still could stimulate immune response after storing at 4℃ for 8 month.
Yang, Yi-Hsien, та 楊倚弦. "Efficacy of novel β-TCP/Collagen composites in ridge preservation: Animal Study". Thesis, 2017. http://ndltd.ncl.edu.tw/handle/942t3x.
Повний текст джерела國立臺灣大學
臨床牙醫學研究所
105
Background: Alveolar ridge remodeling is observed after tooth extraction. It would become the problem if future rehabilitation involved implant placement. Therefore , ridge preservation technique was introduced to solve this kind of problem. Although there are many available products of β-TCP(β-tricalcium phosphate)/Collagen composites for clinical usage, such as for periodontal regeneration and repair of bony defect. There is still lack of ideal products fulfilled the requirement of easily handling and predicable clinical outcome. Some popular product such as Bio-Oss® Collagen may retained too long during its degradation. It may degrade relatively slowly, more residual bone filler after bone modeling. β -TCP also has substantial physical strength; it provides a three-dimensional scaffold for bone regeneration against the pressure of tissue shrinkage . Moreover, β-TCP has the potential to function as a reservoir of calcium and phosphate ions for the local tissue during the degradation process, which possibly results in stimulation of osteoblastic function and promotion of bone formation. Above as though better than traditional β-TCP/Collagen composites. In this project, we will perform animal test to identify its clinical efficacy. Different β-TCP/Collagen composites will be tested in their physical property. Afterward proceeding for further animal experiment in observation the dimensional change of the extraction socket. Six dogs will be used in this project, symmetric extraction sockets will be created and covered with commercial or new developed β-TCP/Collagen composites in this project at different time points to identify its efficacy in ridge augmentation. We hope the β-TCP/Collagen composites will be developed and its superiority in guide bone regeneration will also been identified following this project proceeding. Materials and Methods: The mandibular third premolars and fourth premolars of six dogs were extracted bilaterally, and buccal dehiscence defects were prepared bilaterally on the buccal side of the mandibular third and fourth premolars. Sixteen defects were assigned to four treatment groups: T1 group (β-TCP/10%Collagen composites );T2 group (β-TCP/20%Collagen composites ) ; positive control (Bio-Oss® Collagen); negative control (no grafting material ). Fluorescence bone labeling was administrated subcutaneously three weeks, five weeks and seven weeks post-operatively. The animals were sacrificed 8 weeks after surgery. For histomorphometric analysis, new bone area were measured. New bone volume was measured using microcomputed tomography(micro-CT). Fluorescence microscopic observation was performed to figure out the possible sequence of new bone formation in each group. Result: No adverse effect was found in all four groups after ridge preservation surgery. For new bone area (%) of Histomorphometry, the four groups was 25.02±19.50% for the T1 group, 38.18±6.85% for the T2 group , 32.37±10.74% for the positive control group, and 24.97±8.91% for the negative control group. The differences between each group were not statistically significant. For new bone volume (%)analyzed from micro-CT, the result of the T1 group come close to the positive control group (respectively 71.68±12.63 % and 82.40±14.14 %), which is higher than T2 group (62.00±14.39 %) and the negative control group (31.18±12.57 %).Nevertheless, there is statistical significant between positive control、T1 group and negative control group. Under fluorescence microscopy, the pattern of new bone formation usually starts from the border of the defect toward the central part of the defect. However, the timing and the specific area of new bone formation are different in positive control、T1、T2 and negative control groups. It seems that the test group may delay the time of bone formation (compare with negative control group) ,but more bone gain may find after 5 weeks in the test group. For new bone area (%)of fluorescence microscopy calculated separately in the four groups was 13.88±3.15 % for the T1 group, 12.42±8.37 % for the T2 group , 15.24±8.85 % for the positive control group, and 6.33±3.73% for the negative control group. But the differences between each group were not statistically significant. Conclusion: The β-TCP/Collagen composites seems to have the potential to preserve ridge volume. However, due to limited sample size in this study, there is less possibility that the result between groups achieving statistical significance. More research are needed on investigating the potential of this new β-TCP/Collagen composites for ridge preservation. In addition, the fluorescence bone labeling techniques not only supporting the results of histology and micro-CT , but also assisting us to understand the mechanism of new bone formation in different treatment
Jamuna, M. "Studies on the efficacy of bacteriocins from Lactic acid bacteria as food preservatives and their applicability in non-fermented foods." Thesis, 2004. http://hdl.handle.net/2009/3009.
Повний текст джерелаFerreira, Henrique Paulo Pelica. ""Amor a quanto obrigas…!" - Estudo comparativo da auto-eficácia do uso do preservativo masculino em jovens adultos masculinos e femininos." Master's thesis, 2008. http://hdl.handle.net/10400.12/4646.
Повний текст джерелаTratou-se de um estudo no qual participaram 120 jovens com idades compreendidas entra os 18 e os 30 anos, cujo principal objectivo foi investigar a relação existente entre ambos os géneros e a auto-eficácia ao preservativo masculino nos relacionamentos sexuais. Foram utilizados dois grupos, um feminino composto por 60 raparigas, outro masculino composto por 60 rapazes. Para medir a auto-eficácia foi utilizada uma escala já existente, adaptada para a língua portuguesa, nomeadamente a Escala de Auto-Eficácia Face ao Preservativo de 20 itens de Marín et al. (1998). Em termos gerais pretendeu-se observar se existiam diferenças significativas entre os dois grupos no que respeita às duas variáveis principais auto-eficácia e género e que outras variáveis poderiam estar a influênciar os resultados obtidos. O estudo decorreu no meio estudantil, nomeadamente com estudantes universitários.
This was a study in which we had 120 young person’s participating, with an average age between 18 and 30 years old. The main objective of this study was to investigate the existing relation between both genders and self-efficacy in male condom use in sexual relationships. They were used two groups, one feminine composed by 60 young women, and the other, a male group composed by 60 young men. To measure self-efficacy it was used an existing scale, adapted to Portuguese language, the 20-item Self-Efficacy to Use Condom Scale of Marín et al. (1998). In general terms the objective of this study was to observe the significant differences between the principal variables, self-efficacy to use condom and gender, and to observe what other variables influence results. The study was carried out on the student ambience, with university students.
Khan, Shehnaz. "Efficacy of the cell block technique in diagnostic cytopathology: comparing immunocytochemistry and cytomorphologic preservation on cell block material with conventional cytological preparations." Thesis, 2012. http://hdl.handle.net/10539/13143.
Повний текст джерелаObjective To determine the effectiveness of the cell block technique for immunocytochemical diagnosis by comparing cytomorphologic preservation and immunocytochemistry (ICC) stains in paired cell block and conventional fine needle aspiration (FNA) samples. Study Design This was a prospective study. Material for both conventional smears and cell blocks were collected simultaneously during fine needle aspiration of 50 lesions comprising lymph node, lung and liver masses. Grading of cellularity, morphological preservation, architectural preservation, immunocytochemical staining intensity and presence of background staining were compared on paired FNA smears and cell block samples derived from the same case. Each arm of the paired analysis was performed blindly without knowledge of the grading outcome of the other. The Kappa statistic (Κ) was used to measure inter-rater agreement. Results The fifty samples evaluated included FNAs from the lung, 24/50 (48%); liver, 23/50 (46%) and lymph node, 3/50 (6%). The immunocytochemistry stains consisted of 44/50 (88%) CK7, 44/50 (88%) CK20, 18/50 (36%) TTF1, 10/50 (20%) synaptophysin, 10/50 (20%) Hepar-1 and 7/50 (14%) AE1/3. There was no overall agreement in preservation of cytomorphological detail and ICC staining between the two methods. The Papanicolaou stained conventional FNA smears fared better then cell block for the vi evaluation of nuclear and cytomorphologic characteristics; cells in the cell block were poorly preserved in many cases. The ICC stains worked better on the cell block samples due to lack of background and aberrant staining. Conclusion Conventional FNA smears and cell blocks complement each other. Our results indicate that it would be optimal to use both modalities in the diagnostic work-up of mass lesions amenable to FNA diagnosis; the former to assess morphology, and the latter for optimal immunocytochemistry results. In resource constrained settings, the cost implications of performing both conventional and blocked smears on all FNA material warrants further evaluation.
Tripathi, Anamika. "Weighted gene co-expression network analysis of colorectal patients to identify right drug-right target for potent efficacy of targeted therapy." Thesis, 2017. https://doi.org/10.7912/C22Q09.
Повний текст джерелаColon rectal cancer (CRC) is one of the most common cancers worldwide. It is characterized by the successive accumulation of mutations in genes controlling epithelial cell growth and differentiation leading to genomic in-stability. This results in the activation of proto-oncogene(K-ras), loss of tumor suppressor gene activity and ab-normality in DNA repair genes. Targeted therapy is a new generation of cancer treatment in which drugs attack targets which are specific for the cancer cell and are critical for its survival or for its malignant behavior. Survival of metastatic CRC patients has approximately doubled due to the development of new combinations of stan-dard chemotherapy, and the innovative targeted therapies, such as monoclonal antibodies against epidermal growth factor receptor (EGFR) or monoclonal antibodies against vascular endothelial growth factor (VEGFR).The study is to exhibit the need for right drug-right target and provides a proof of principle for potent efficacy of molecular targeted therapy for CRC. We have performed the weighted gene co-expression network analysis for three different patient cohort treated with different targeted therapy drugs. The results demonstrates the variation across different treatment regime in context of transcription factor networks. New significant tran-scription factors have been identified as potential biomarker for CRC cancer including EP300, STAT6, ATF3, ELK1, HNF4A, JUN, TAF1, IRF1, TP53, ELF1 and YY1. The results provides guidance for future omic study on CRC and additional validation work for potent biomarker for CRC.
Gold, Sharon. "Measuring social competence, task competence and self-protection in an organisational context." Thesis, 2009. http://hdl.handle.net/1959.13/44576.
Повний текст джерелаIn Chapter 1, I describe social competence, task competence and self-protection in an organisational context. In Chapter 2, I review key self theories and relate them to the self-competence construct. In Chapter 3, I review the research on self-competence to show that there is a need for a construct of social competence and self-protection. I discuss the limitations of three self-competence theories: Bandura’s (1977) self-efficacy theory, Williams and Lillibridge’s (1992) self-competence theory and Tafarodi & Swann’s (1995) self-competence/self-liking theory. In Chapter 4, I present my selfcompetence model. I raise the research questions and specify my hypotheses. In Chapter 5, I describe the construction of Social and Task Competence Scale. I present evidence of the reliability and factor structure of the Social and Task Competence Scale. I concluded that scale revisions were needed. In Chapter 6, I present evidence of the reliability, factor structure and predictive validity of the revised Social and Task Competence Scale and Self-Protection Scale. I describe the results of an experiment that investigated the interaction of task setting, social competence, task competence and selfprotection. I concluded that the measures predicted performance. In Chapter 7, I investigate the factor structure and reliability of the revised Social and Task Competence Scale and revised Self-Protection Scale. I provide evidence of the convergent and discriminant validity of these measures with reliable measures of self-competence, selfesteem, self-monitoring, personality and social desirability. In Chapter 8, I investigate the factor structure and reliability of the Social and Task Competence Scale and Self-Protection Scale after final revisions and show that these measures are acceptable for use in scientific research. I present evidence of their convergent validity with a valid andreliable measure of emotional intelligence, and describe experimental results that supported the hypothesised relationships between perceived task difficulty, social competence, task competence and self-protection and task performance. In Chapter 9, I discuss the implications of my research for self-competence theory, self-regulation and self-esteem and the prediction of social and task performance in organisations.
Gold, Sharon. "Measuring social competence, task competence and self-protection in an organisational context." 2009. http://hdl.handle.net/1959.13/44576.
Повний текст джерелаIn Chapter 1, I describe social competence, task competence and self-protection in an organisational context. In Chapter 2, I review key self theories and relate them to the self-competence construct. In Chapter 3, I review the research on self-competence to show that there is a need for a construct of social competence and self-protection. I discuss the limitations of three self-competence theories: Bandura’s (1977) self-efficacy theory, Williams and Lillibridge’s (1992) self-competence theory and Tafarodi & Swann’s (1995) self-competence/self-liking theory. In Chapter 4, I present my selfcompetence model. I raise the research questions and specify my hypotheses. In Chapter 5, I describe the construction of Social and Task Competence Scale. I present evidence of the reliability and factor structure of the Social and Task Competence Scale. I concluded that scale revisions were needed. In Chapter 6, I present evidence of the reliability, factor structure and predictive validity of the revised Social and Task Competence Scale and Self-Protection Scale. I describe the results of an experiment that investigated the interaction of task setting, social competence, task competence and selfprotection. I concluded that the measures predicted performance. In Chapter 7, I investigate the factor structure and reliability of the revised Social and Task Competence Scale and revised Self-Protection Scale. I provide evidence of the convergent and discriminant validity of these measures with reliable measures of self-competence, selfesteem, self-monitoring, personality and social desirability. In Chapter 8, I investigate the factor structure and reliability of the Social and Task Competence Scale and Self-Protection Scale after final revisions and show that these measures are acceptable for use in scientific research. I present evidence of their convergent validity with a valid andreliable measure of emotional intelligence, and describe experimental results that supported the hypothesised relationships between perceived task difficulty, social competence, task competence and self-protection and task performance. In Chapter 9, I discuss the implications of my research for self-competence theory, self-regulation and self-esteem and the prediction of social and task performance in organisations.