Добірка наукової літератури з теми "Potassium 41"

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Статті в журналах з теми "Potassium 41":

1

Korsun, S. H., A. V. Davydiuk, and V. V. Hirnyk. "The effect of fertilizing systems on the potassium capacity of dark gray soil." Interdepartmental thematic scientific collection "Agriculture" 2, no. 95 (December 22, 2018): 35–41. http://dx.doi.org/10.31073/zem.95.35-41.

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Purpose. Identify the features of changes in the factor of potassium capacity of dark gray soil under long-term systematic application of different doses of mineral and organic fertilizers. Methods. Field, laboratory, mathematical and statistical. Results. At various intensities of fertilizer systems and fertilizer ratios, it has been established that the long (30 years) use of organic and mineral fertilizers contributed not only to stabilization but also to the restoration of the stock of moving potassium in the arable soil layer in comparison with the initial data (1987).The growth of mobile potassium content was consistent with the increase in the agrochemical load in crop rotation. Conclusions. Long-term systematic application for 1987–2000 years mineral fertilizers in doses of 265–397 kg of NPK on the background of 10 tons of manure per 1 ha of crop rotation, in 2001–2010 years – 211–316,5 kg of NPK per 1 ha, and in 2011–2017 years – 217,5–326,4 kg of NPK per 1 ha on the background plowing crop by-products had a significant impact in the factor on the capacity factor of potassium of dark gray podzolized soil, ensuring it is elevated and very high level.
2

Afridi, Muhammad Saeed, Muhammad Suleman Khan, Sohail Rashid, Zain Mehmood Butt, Rimsha Tauqeer, Mattiur Rahman, Ashiqullah Arman, and Iqra Waheed. "Potassium Imbalance Leading to Arrhythmias in Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass." Pakistan Journal of Medical and Health Sciences 17, no. 3 (March 30, 2023): 528–30. http://dx.doi.org/10.53350/pjmhs2023173528.

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Objective: To determine the frequency of factors that cause potassium imbalance in patients with postoperative arrhythmias after cardiac Bypass surgery Material and methods: During the time period of 2 November 2018 through 10 January 2020, 100 patients with heart disease receiving open-heart surgery were enrolled in a prospective observational research conducted by the cardiac surgery department at the Punjab Institute of Cardiology in Lahore. Both genders of age 17-70 years were included and patients with cyanotic heart disease congenital heart disease, previous cardiac surgery and urgent CABG were excluded. Results: Our results showed that of 100 patients, 59 (59%) were male and 41 (41%) were female and the mean age was14.243 ± 50.12 years. 6 patients had preexisting renal failure and 9 had postoperative renal failure. Overall potassium imbalance was noted in 39 patients, 33 were hypokalemic and 6 were hyperkalemic and the mean potassium with S.D was 3.95±0.83 and 37 had postoperative arrhythmias out of which 18 (54.5%) were hypokalemic and 2 (33.3%) were hyperkalemic. Preoperative drugs, preexisting renal failure, CPB time, aortic cross clamp time, intraoperative potassium levels, time on ventilation, postoperative urine output, potassium infusion, postoperative renal failure, arrhythmias and total hospital stay were found to be statistically significant. Conclusion: Potassium imbalance post-cardiopulmonary bypass is major factor that may lead to increased risk of postoperative arrhythmias. Keywords: Potassium imbalance, cardiopulmonary bypass, postoperative arrhythmias, renal failure, hypokalemia
3

Bundgaard, Henning, and Keld Kjeldsen. "Potassium depletion increases potassium clearance capacity in skeletal muscles in vivo during acute repletion." American Journal of Physiology-Cell Physiology 283, no. 4 (October 1, 2002): C1163—C1170. http://dx.doi.org/10.1152/ajpcell.00588.2001.

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Muscular K uptake depends on skeletal muscle Na-K-ATPase concentration and activity. Reduced K uptake is observed in vitro in K-depleted rats. We evaluated skeletal muscle K clearance capacity in vivo in rats K depleted for 14 days. [3H]ouabain binding, α1 and α2 Na-K-ATPase isoform abundance, and K, Na, and Mg content were measured in skeletal muscles. Skeletal muscle K, Na, and Mg and plasma K were measured in relation to intravenous KCl infusion that continued until animals died, i.e., maximum KCl dose was administered. In soleus, extensor digitorum longus (EDL), and gastrocnemius muscles K depletion significantly reduced K content by 18%, 15%, and 19%, [3H]ouabain binding by 36%, 41%, and 68%, and α2 isoform abundance by 34%, 44%, and 70%, respectively. No significant change was observed in α1 isoform abundance. In EDL and gastrocnemius muscles K depletion significantly increased Na (48% and 59%) and Mg (10% and 17%) content, but only tendencies to increase were observed in soleus muscle. K-depleted rats tolerated up to a fourfold higher KCl dose. This was associated with a reduced rate of increase in plasma K and increases in soleus, EDL, and gastrocnemius muscle K of 56%, 42%, and 41%, respectively, but only tendencies to increase in controls. However, whereas K uptake was highest in K-depleted animals, the K uptake rate was highest in controls. In vivo K depletion is associated with markedly increased K tolerance and K clearance despite significantly reduced skeletal muscle Na-K-ATPase concentration. The concern of an increased risk for K intoxication during K repletion seems unwarranted.
4

Solihudin, Solihudin, Atiek Rostika Noviyanti, and Iman Rahayu. "Pengaruh Ukuran Partikel Arang Sekam Padi Dan Waktu Refluks terhadap Kadar Abudan Daya Serap Karbon Sekam Padi." Jurnal Natur Indonesia 17, no. 1 (March 30, 2017): 33. http://dx.doi.org/10.31258/jnat.17.1.33-41.

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The highest content in rice husk is ash with its main component of silica. Silica in ash causes the low adsorption capacity. Activated carbon from rice husk can be obtained by lowering the ash content. The aim of this study is determine the effect of particle size of charcoal and reflux time the ash content using a solution of potassium carbonate. The activation of rice husk char was carried out by using reflux methods with a potassium carbonate solution. The resulted carbon was washed using hydrochloric acid tested using iodine and methylene blue to examine of its adsorbance. The particle size of rice husk and reflux time decrease ash content in rice husk. In general, husk with the size of 80 mesh can produce carbon with low ash content and high absorption using reflux time at least for 120 minutes. Rice husk size of 100 mesh refluxing with potassium carbonate for 150 minutes can reduce the ash content as 91.85% and adsorptivity of the iodine at 331 mg.g -1 .
5

Lin, Yang, Mingzhong Cai, Zhiqiang Fang, and Hong Zhao. "Highly efficient heterogeneous copper-catalyzed decarboxylative cross-coupling of potassium polyfluorobenzoates with aryl halides leading to polyfluorobiaryls." RSC Advances 7, no. 55 (2017): 34722–29. http://dx.doi.org/10.1039/c7ra05711c.

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6

Jat, M. K., P. K. Yadav, R. Singh, A. Tikkoo, S. S. Yadav, and R. S. Dadarwal. "Response of green gram (Vigna radiata L.) to potassium fertilization in coarse textured soils of Southern Haryana, India." Journal of Environmental Biology 41, no. 6 (November 15, 2020): 1621–25. http://dx.doi.org/10.22438/jeb/41/6/si-228.

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Aim: To evaluate the optimum dose and potassium application on K uptake by green gram and its buildup/depletion in soil to overcome the production of pulses in South West part of Haryana. Methodology: A series of field experiments and on farm trials were conducted during 2012 to 2016 at the Regional Research Station, CCS HAU, Bawal and at the farmers field to study the response of green gram to potassium fertilization in coarse textured medium K status soils of southern Haryana, India. Five levels of potassium (0, 10, 20, 30 and 40 kg K2O ha-1) were evaluated in randomized block design with three replications. Results: The results of study revealed that green gram seed yield increased significantly with application of potassium at 20 kg K2O ha-1. Potassium fertilization also significantly increased total K uptake by green gram at each level of potassium application and helped in preventing the depletion of available soil K and enhanced its content in the soil. The mean K use efficiency varied from 38.30 to 54.15 per cent, being maximum with application of 20 kg K2O ha-1 (54.15 %). The mean economic data analysis revealed that benefit cost ratio also increased with potassium fertilization. Interpretation: On farm trials conducted on farmers field revealed that application of 20 kg K2O ha-1 in coarse textured low to medium potash status soils is optimum for higher yield, returns and maintenance of available K status in soil.
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Morgan, Leah E., Danielle P. Santiago Ramos, Brett Davidheiser-Kroll, John Faithfull, Nicholas S. Lloyd, Rob M. Ellam та John A. Higgins. "High-precision 41K/39K measurements by MC-ICP-MS indicate terrestrial variability of δ41K". Journal of Analytical Atomic Spectrometry 33, № 2 (2018): 175–86. http://dx.doi.org/10.1039/c7ja00257b.

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8

Meyer, Harald, Günter Schmidt-Lukasch, Gerhard Baum, Werner Massa, and Armin Berndt. "Dianion eines Methylendiborirans, Synthese seiner Alkali- und Magnesiumsalze und Struktur seines Dikaliumsalzes / Dianion of a Methylenediborirane, Synthesis of its Alkali and Magnesium Salts and Structure of its Dipotassium Salt." Zeitschrift für Naturforschung B 43, no. 7 (July 1, 1988): 801–6. http://dx.doi.org/10.1515/znb-1988-0703.

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Lithium, sodium, potassium, caesium and magnesium salts of the dianion of 1,2-di-tert-butyl-3- [bis(trimethylsilyl)methylene]-1,2-diborirane have been synthesized and charactarized by 13C and 11B NMR spectroscopy. X-ray structure analysis of the di-potassium salt proves cyclic derealization of two. π-electrons in the CB2-ring by short C-B (150 pm) and B -B (158 pm) bonds. The exocyclic C-C bond (150 pm) is bridged by two potassium ions. One of them contacts the boron atoms of a neighbouring dianion leading to a helicoidal infinite chain with 41-symmetry along the c direction.
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Flyvbjerg, A., I. Dørup, M. E. Everts, T. Clausen, and H. Ørskov. "41 EVIDENCE THAT POTASSIUM DEFICIENCY INDUCES GROWTH RETARDATION THROUGH REDUCED SOMATOMEDIN C PRODUCTION." Pediatric Research 24, no. 4 (October 1988): 524. http://dx.doi.org/10.1203/00006450-198810000-00062.

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Martínez-Pineda, Montserrat, Antonio Vercet, and Cristina Yagüe-Ruiz. "Are Food Additives a Really Problematic Hidden Source of Potassium for Chronic Kidney Disease Patients?" Nutrients 13, no. 10 (October 12, 2021): 3569. http://dx.doi.org/10.3390/nu13103569.

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Dietary treatment in chronic kidney disease (CKD) recommends limiting the consumption of foods rich in potassium to reduce risk of hyperkalemia. Currently, the increased supply of processed foods on the market could be a new “hidden” source of potassium for these patients, which is causing concern among health professionals who treat them. The aim of this study was to check which EU authorized food additives contain potassium, its conditions of use and classified them according to their risk for CKD patients. In addition, the frequency of appearance of potassium additives in processed foods in a European sample through the analysis of 715 products labeling from France, Germany, and Spain were evaluated. Results showed 41 potassium-containing additives allowed in the European Union, but only 16 were identified, being the most frequent: E202; E252, E340, E450, E452, E508, and E950. The 37.6% of the processed products analyzed contained at least one potassium additive. The food categories that showed the greatest presence of additives were breaded products, meat derivatives, non-alcoholic beverage, ready-to-eat products, and cereal derivatives. Potassium additives are widely distributed in processed foods and therefore pose a risk of hidden sources of potassium in CKD dietary management. These results could be really useful for developing educational tools for CKD patients.

Дисертації з теми "Potassium 41":

1

Zemmouri, Samir. "Développement et réalisation d’un dispositif expérimental permettant la production d’un condensat de Bose Einstein de Potassium 41." Thesis, Lille 1, 2019. http://www.theses.fr/2019LIL1R060.

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Les systèmes lasers limitent la taille des pièges magnéto optiques car leurs puissances optiques sont limitées. Cette limite a une impacte directe sur la taille des condensats de Bose Einstein. L’objectif de cette thèse a été de réaliser un système laser innovant qui permet d’obtenir des puissances optiques significativement plus importantes afin d’obtenir des condensats de Bose Einstein de plus grande taille
Laser systems limit the size of magneto-optical traps because their optical powers are limited. This limit has a direct impact on the size of Bose Einstein condensates. The objective of this thesis was to realize an innovative laser system which allows to obtain significantly higher optical powers in order to obtain larger Bose Einstein condensates
2

Zemmouri, Samir. "Développement et réalisation d’un dispositif expérimental permettant la production d’un condensat de Bose Einstein de Potassium 41." Electronic Thesis or Diss., Université de Lille (2018-2021), 2019. http://www.theses.fr/2019LILUR060.

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Les systèmes lasers limitent la taille des pièges magnéto optiques car leurs puissances optiques sont limitées. Cette limite a une impacte directe sur la taille des condensats de Bose Einstein. L’objectif de cette thèse a été de réaliser un système laser innovant qui permet d’obtenir des puissances optiques significativement plus importantes afin d’obtenir des condensats de Bose Einstein de plus grande taille
Laser systems limit the size of magneto-optical traps because their optical powers are limited. This limit has a direct impact on the size of Bose Einstein condensates. The objective of this thesis was to realize an innovative laser system which allows to obtain significantly higher optical powers in order to obtain larger Bose Einstein condensates
3

Pachot, Stéphanie. "Etudes structurales des composés à échelles de spins du type A14 Cu24 O[41+(delta)] (A = Sr, Ca, Ba, Nd, Y, Na, K)." Université Joseph Fourier (Grenoble), 1999. http://www.theses.fr/1999GRE10133.

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4

Denis, Maxime. "Construction d'une expérience de Condensat de Bose-Einstein de 41K pour l'étude du rotateur frappé atomique." Electronic Thesis or Diss., Université de Lille (2022-....), 2022. http://www.theses.fr/2022ULILR064.

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Ce manuscrit présente la réalisation d'un dispositif expérimental permettant de produire des condensats de Bose-Einstein de potassium 41. Cette expérience a été construite dans le but d'étudier le modèle du rotateur frappé en présence d'interactions. Le choix du potassium 41 pour cette expérience est motivé par deux raisons. La première est que la longueur de diffusion de cet atome est positive (ce qui permet une condensation aisée) et qu'il possède des résonances de Feshbach accessibles. La seconde est que les longueurs d'ondes de ses transitions de refroidissement peuvent être générées par des sources lasers fibrées puissantes du domaine télécom doublées en fréquence. Cela a pour avantage de pouvoir fabriquer des systèmes lasers stables et robustes pour les étapes de refroidissement laser et de piégeage optique du potassium 41. La particularité de notre système réside dans la génération de fréquence qui a lieu en amont des étapes d'amplification à haute puissance et de doublage en fréquence. Le développement de ces bancs lasers agissant sur les deux transitions de refroidissement D1 et D2 a permis de mener à bien les étapes de refroidissement laser. Grâce à ces bancs lasers, un piège magnéto-optique rassemblant 3x10^(9) atomes a été obtenu. La compression et le refroidissement avec une mélasse grise de ce piège magnéto-optique a permis d'atteindre une température de 16 µK et une densité dans l'espace des phases de 10^(-6). Les étapes de refroidissement évaporatif qui suivent sont réalisées successivement avec un piège quadrupolaire, un piège hybride (piège quadrupolaire + piège optique) et pour terminer un piège optique croisé. Des condensats de 500 000 atomes ont été observés dans ce piège optique croisé. Nous avons aussi identifié des résonances de Feshbach qui permettront le contrôle des interactions. Pour l'étude du rotateur frappé, un système laser pulsé original a été conçu en parallèle. La réalisation de ce système a été faite à partir d'un laser pulsé télécom amplifié à haute puissance doublé en fréquence. Ce système produit des pulses laser proches infrarouge avec des impulsions de 10 ns, une fréquence de répétition comprise entre 100 kHz et 500 kHz et une puissance crête optique allant jusqu'à 350W. Ce banc laser pulsé nous a permis de réaliser les premières expériences du rotateur frappé de cette expérience. Un contrôle des interactions avec les résonances de Feshbach identifiées nous permettra d'étudier par la suite le modèle du rotateur frappé en présence d'interactions
This manuscript presents the realization of an experimental device to produce Bose-Einstein condensates of potassium 41. This experiment was built to study the model of the kicked rotor in the presence of interactions. The choice of potassium 41 for this experiment is motivated by two reasons. The first is that the diffusion length of this atom is positive (allowing easy condensation) and has accessible Feshbach resonances. The second is that the wavelengths of its cooling transitions can be generated by powerful fiber laser sources in the telecom domain doubled in frequency. This has the advantage of being able to manufacture stable and robust laser systems for laser cooling and optical trapping of potassium 41. The particularity of our system lies in the frequency generation that takes place before the high power amplification and frequency doubling stages. The development of these laser benches acting on the two cooling transitions D1 and D2 enabled the laser cooling stages to be completed. Thanks to these laser benches, a magneto-optical trap gathering 3x10^(9) atoms was obtained. Compression and cooling with grey molasses of this magneto-optical trap allowed to reach a temperature of 16 µK and a density in the space of phases of 10^(-6). The following evaporative cooling steps are carried out successively with a quadrupolar trap, a hybrid trap (quadrupolar trap + optical trap) and to finish a crossed optical dipole trap. Condensates of 500,000 atoms were observed in this crossed optical dipole trap. We also identified Feshbach resonances that will allow the control of interactions. For the study of the kicked rotor, an original pulsed laser system was designed in parallel. The realization of this system was made from a high-power amplified telecom pulsed laser doubled in frequency. This system produces near infrared pulses at a repetition frequency between 100 kHz to 500 kHz with peak optical power up to 350W. This pulsed laser bench allowed us to perform the first experiments of the kicked rotor from this experiment. A control of the interactions with the identified Feshbach resonances will allow us to study the model of the kicked rotor in the presence of interactions
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Hance, Michael W. "The Effects of 17- Beta Estradiol on G-Protein Inwardly Rectifying Potassium Channels (GIRKs) in Breast Cancer." 2009. http://trace.tennessee.edu/utk_graddiss/41.

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Breast cancer is a leading cause of cancer death and in 2009, the American Cancer Society estimates that over 192,000 new cases of breast cancer will be diagnosed, and over 40,000 women will die from breast cancer. Estrogen (E2) is required for normal female development and reproduction, but long-term exposure is carcinogenic and considered a risk factor for breast cancer. Membrane ion channels are essential for cell proliferation and are suggested to have a role in cancer, especially potassium channels. In the present study, we investigate the effects of estrogen and the estrogen antagonist ICI182780 on G-protein inwardly rectifying potassium channels (GIRK) in estrogen responsive MCF-7 breast cancer cells. GIRK1 and GIRK2 specific channels are thought to play a major role in rapid channel activation. We found increases in GIRK1 and GIRK2 membrane protein levels in response to estrogen treatment, as well as increases in intracellular potassium concentrations and cellular proliferation. ICI182780 treatment increased GIRK1, GIRK2 and GIRK4 membrane protein levels but resulted in an initial decrease in intracellular potassium concentration and decreased cell proliferation. GIRK1 RNAi knockdown decreased estrogen receptor alpha protein levels and activation. In addition, estrogen treatment resulted in increased phosphorylation of specific members of GPCR and MAPK signaling pathways that have been shown to be responsive to GIRK1 knockdown. Using microarray analysis of nontreated and E2 treated MCF7 cells, we observed 489 differentially expressed genes (283 upregulated and 206 downregulated) that were comprised largely of transcription and cell cycle associated genes. This study identified several human cell cycle associated genes that are both responsive to E2 treatment and are functionally correlated with GIRKs. Five genes were selected for further analysis by real time PCR. Our data suggests that specific GIRK channel composition at the cell membrane may be stimulated by estrogen exposure or downstream targets of estrogen signaling and may contribute to increased cell proliferation in MCF-7 breast cancer cells. Taken together, these data add further support of GIRK involvement in cancer progression and identify some potential biological roles of GIRKs in cancer biology beyond the initilal findings of GIRK1 assciation in metastatic breast cancer.

Частини книг з теми "Potassium 41":

1

Sukhoruchkin, S. I., and Z. N. Soroko. "Excited Nuclear States for K-41 (Potassium)." In Supplement to I/25 A-E, 901–24. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-47801-1_168.

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Sukhoruchkin, S. I., and Z. N. Soroko. "Excited Nuclear States for K-41 (Potassium)." In Nuclei with Z = 1 - 29, 2400. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-22798-1_299.

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3

Sukhoruchkin, S. I., and Z. N. Soroko. "Excited Nuclear States for K-41 (Potassium)." In Supplement to I/25 A-F, 1245–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-48875-1_181.

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4

Sukhoruchkin, S. I., and Z. N. Soroko. "Neutron Resonance Parameters for K-41 (Potassium)." In Neutron Resonance Parameters, 416–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-87866-7_48.

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5

Sukhoruchkin, S. I., and Z. N. Soroko. "Neutron Resonance Parameters for K-41 (Potassium)." In Supplement to Volume I/24, 314–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45603-3_50.

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6

Robinson, John M., Andrey Kosolapov, and Carol Deutsch. "Tertiary and Quaternary Structure Formation of Voltage-Gated Potassium Channels." In Ion Channels, 41–52. Totowa, NJ: Humana Press, 2006. http://dx.doi.org/10.1385/1-59745-095-2:41.

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7

Sukhoruchkin, S. I., and Z. N. Soroko. "Atomic Mass and Nuclear Binding Energy for K-41 (Potassium)." In Nuclei with Z = 1 - 54, 1324–26. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-69945-3_605.

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Тези доповідей конференцій з теми "Potassium 41":

1

Higgins, John, Cornelia Spetea, Danielle Saniago Ramos, Jang Youn, Alicia McDonough, Stefania Gili, Darren Ha, and Scott Kanoski. "Stable Potassium Isotopes (41K/39K) Track Transcellular and Paracellular Potassium Transport in Biological Systems." In Goldschmidt2022. France: European Association of Geochemistry, 2022. http://dx.doi.org/10.46427/gold2022.13125.

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2

Urschel, R., A. Borsutzky, D. Rvtz, and R. Wallenstein. "The potassium niobate OPO and the advantages of tangential phase-matching." In The European Conference on Lasers and Electro-Optics. Washington, D.C.: Optica Publishing Group, 1996. http://dx.doi.org/10.1364/cleo_europe.1996.ctuo3.

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Powerful IR radiation tunable in the wavelength range of 1.44-4.05 μm can be generated by an OPO of potassium niobate (KNbO3) pumped by the fundamental of a pulsed Nd:YAG laser 1. The OPO consists of a 10-mm-long AR- coated crystal (critical type-l phase-matching, θ=41°, ϕ=0°) placed in a 12-mm-long flat-flat mirror cavity resonant for the signal wave The energy density at threshold increases from 0.485 J/cm2 at 1.9 μm to more than 0.7 J/cm below 1 48 μm. To avoid damage of the coating of the KNbO3 crystal the pump energy densities should be less than 1 J/cm2. Due to the rather large walk-off of 3.5° the threshold decreases with increasing pump beam diameter (from 0.6 J/cm3 at 2.35 mm to 0.485 J/cm2 at 4,85 mm). Hence, enlarging the pump beam diameter front 3.05 mm to 4.85 mm. the OPO energy and efficiency increases at constant pump energy density (0.975 J/cm2) from 6.4 mJ to 30 mJ and from 9 % to 16.7 %, respectively.
3

Alqahtani, H. S., M. K. Alarfaj, and M. A. Alotaibi. "Environmentally Friendly Shale Inhibitor Water-Based Drilling Fluids." In International Petroleum Technology Conference. IPTC, 2024. http://dx.doi.org/10.2523/iptc-24070-ea.

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Анотація:
Abstract Environmentally friendly Mobil crystalline materials (MCM-41) from the family of Mesoporous Silica Nanoparticles (MSNs) has been used for the first time as shale inhibitors in water-Based Drilling Fluids with full drilling fluid compositions. This shale inhibitor used in this study to eliminate the use of toxic high potassium chloride (KCl) concentration in shale drilling operations and reduce the waste management associated cost with drilling fluid treatment and disposal. The hot rolling dispersion test of MCM41 shale inhibitor with Silurian shale samples revealed to be an effective candidate with significant interaction reduction between the drilling fluids and the shale particles. This new shale inhibitor maintains the integrity of the cuttings and minimize the interaction of fluids with shale sections during the rolling test. XRD, TEM and TGA have measured and discussed in previous publication. Although the application of nanoparticles to improve the performance of conventional water-based drilling fluid was studied by researchers, it is the novelty of this research to eliminate use of KCl and to develop the new generation of shale water-based drilling fluid with economical consideration and lower environmental impact.

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