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Автор: Grafiati
Опубліковано: 10 грудня 2022
Оновлено: 28 січня 2023

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Статті в журналах з теми "Postprandial blood glucose"

1

American Diabetes Association. "Postprandial Blood Glucose." Clinical Diabetes 19, no. 3 (July 1, 2001): 127–30. http://dx.doi.org/10.2337/diaclin.19.3.127.

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2

Parker, Lewan, Dale J. Morrison, Andrew C. Betik, Katherine Roberts-Thomson, Gunveen Kaur, Glenn D. Wadley, Christopher S. Shaw, and Michelle A. Keske. "High-glucose mixed-nutrient meal ingestion impairs skeletal muscle microvascular blood flow in healthy young men." American Journal of Physiology-Endocrinology and Metabolism 318, no. 6 (June 1, 2020): E1014—E1021. http://dx.doi.org/10.1152/ajpendo.00540.2019.

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Oral glucose ingestion leads to impaired muscle microvascular blood flow (MBF), which may contribute to acute hyperglycemia-induced insulin resistance. We investigated whether incorporating lipids and protein into a high-glucose load would prevent postprandial MBF dysfunction. Ten healthy young men (age, 27 yr [24, 30], mean with lower and upper bounds of the 95% confidence interval; height, 180 cm [174, 185]; weight, 77 kg [70, 84]) ingested a high-glucose (1.1 g/kg glucose) mixed-nutrient meal (10 kcal/kg; 45% carbohydrate, 20% protein, and 35% fat) in the morning after an overnight fast. Femoral arterial blood flow was measured via Doppler ultrasound, and thigh MBF was measured via contrast-enhanced ultrasound, before meal ingestion and 1 h and 2 h postprandially. Blood glucose and plasma insulin were measured at baseline and every 15 min throughout the 2-h postprandial period. Compared with baseline, thigh muscle microvascular blood volume, velocity, and flow were significantly impaired at 60 min postprandial (−25%, −27%, and −46%, respectively; all P < 0.05) and to a greater extent at 120 min postprandial (−37%, −46%, and −64%; all P < 0.01). Heart rate and femoral arterial diameter, blood velocity, and blood flow were significantly increased at 60 min and 120 min postprandial (all P < 0.05). Higher blood glucose area under the curve was correlated with greater MBF dysfunction ( R2 = 0.742; P < 0.001). Ingestion of a high-glucose mixed-nutrient meal impairs MBF in healthy individuals for up to 2 h postprandial.
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Shrestha, L., B. Jha, B. Yadav, and S. Sharma. "Correlation between fasting blood glucose, postprandial blood glucose and glycated hemoglobin in non-insulin treated type 2 diabetic subjects." Sunsari Technical College Journal 1, no. 1 (September 16, 2013): 18–21. http://dx.doi.org/10.3126/stcj.v1i1.8654.

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Background: Diabetes mellitus (DM) comprises a group of common metabolic disorders that share phenotype of hyperglycemia. Objectives: This study was conducted to determine the correlation between glucose monitoring by fasting blood glucose or two hours postprandial blood glucose with glycated hemoglobin (HbA1c) in type 2 diabetic patients. Method: A cross sectional study was conducted over a period of six month in the Department of Biochemistry. Institute of Medical, Tribhuvan University Teaching Hospital. Sixty inpatients with Diabetes mellitus type 2 were assessed for daily fasting and postprandial blood sugar for 15 consecutive days. HbA1c was measured on the 15th day. Result: Both postprandial blood glucose and fasting blood glucose significantly correlated with HbA1c. Postprandial blood glucose showed better correlation to HbA1c than fasting blood glucose (r = 0.630, P <0.001 vs. r =0.452, P = 0.05). Conclusion: These results show that postprandial blood glucose correlated better than fasting blood glucose to HbA1c. Thus, postprandial blood glucose predicted overall glycemic control better than fasting blood glucose. This finding has potential implications for treatment and monitoring of metabolic control in type-2 diabetes. DOI: http://dx.doi.org/10.3126/stcj.v1i1.8654 Sunsari Technical College Journal Vol.1(1) 2012 18-21
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Adak, Manoranjan, and Hari Prasad Upadhyay. "Influence of Aging on HbA1C: A Cross-Sectional Study on Diabetic Population Attending a Tertiery Care Center of Central Nepal." Journal of College of Medical Sciences-Nepal 18, no. 3 (November 4, 2022): 227–34. http://dx.doi.org/10.3126/jcmsn.v18i3.45504.

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Background: Diabetes mellitus is increasing day by day throughout the globe. So, early diagnosis of diabetes is crucially important in reduction of the complications. This study was conducted to determine the correlation between glucose monitoring by fasting blood glucose and two hours postprandial blood glucose with glycated hemoglobin (HbA1c) in diabetic patients and evaluate whether glycohemoglobin levels increase with age in both sexes Methods: A hospital-based analytical cross-sectional study was carried out from March 2020 to December 2021 in diabetic patients attending at outpatient department (OPD) of College of Medical College and Teaching Hospital, Bharatpur, Chitwan. The total number patients was 696 people. HbA1c, fasting blood sugar (FBS) and postprandial blood sugar (PPBS) were analyzed. Results: Both postprandial blood glucose and fasting blood glucose significantly correlated with HbA1c. Postprandial blood glucose showed better correlation to HbA1c than fasting blood glucose (r = 0.630, P <0.001 vs. r =0.452, P = 0.05). Conclusions: These results show that postprandial blood glucose correlated better than fasting blood glucose to HbA1c. Thus, postprandial blood glucose predicted overall glycemic control better than fasting blood glucose. Based on our study, we may concluded a significant correlation exist between age and HbA1c in Nepalese population.
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Wulansari, Arin, Fryta Ameilia Luthfinnisa, Fuadah Uyun, Dwi Retnoningrum, Fifin Luthfia Rahmi, and Arief Wildan. "Pengaruh lama mengunyah terhadap kadar glukosa postprandial dewasa obesitas." Jurnal Gizi Indonesia 8, no. 1 (February 6, 2020): 24. http://dx.doi.org/10.14710/jgi.8.1.24-30.

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Background: Obesity cause various physiological changes in the body, one of which is insulin resistance causes high blood glucose levels. Chewing is a stimulus of cephalic phase responses and sensory stimulation that can increase hormones releasing such as insulin, ghrelin, cholecystokinin (CCK) and glucagon like peptide-1 (GLP-1). Chewing plays important role in determining postprandial plasma glucose concentration.Objective: Investigate the effect of chewing on postprandial blood glucose in obese adults.Method: This was true experimental research. Research subjects were treated in the form of chewing 22 times and 40 times each mouthful. Blood glucose levels were measured using glucometer on fasting blood glucose and postprandial blood glucose 15 minutes, 30 minutes, 60 minutes, and 120 minutes. Statistical test using Independent t-test.Results: The mean postprandial glucose levels in the 22 chews group at 15 minutes, 30 minutes, 60 minutes, and 120 minutes were 112.11 ± 14.3328, 126.11 ± 15.667, 116.94 ± 15.539, and 89.67 ± 11.668 . While the mean postprandial blood glucose levels in the 40 chews group at 15 minutes, 30 minutes, 60 minutes, and 120 minutes were 122.22 ± 14.381, 129.61 ± 15.112, 109.50 ± 14.995, and 85.83 ± 13.963. There were statistically significant differences between chewing groups 22 times and chewing 40 times on fasting blood glucose and 15 minutes postprandial blood glucose (p = 0.041 and p = 0.042), while on 30 minutes postprandial glucose testing, 60 minutes , and 120 minutes there was no significant difference (p> 0.05).Conclusion: There was significant differences in 15 minutes postprandial blood glucose level between group 22 times chewing and 40 times chewing each mouthful.
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Röhling, Martin, Wonnemann, Kragl, Klein, Heinemann, Martin, and Kempf. "Determination of Postprandial Glycemic Responses by Continuous Glucose Monitoring in a Real-World Setting." Nutrients 11, no. 10 (September 27, 2019): 2305. http://dx.doi.org/10.3390/nu11102305.

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Background: Self-monitoring of blood glucose using capillary glucose testing (C) has a number of shortcomings compared to continuous glucose monitoring (CGM). We aimed to compare these two methods and used blood glucose measurements in venous blood (IV) as a reference. Postprandial blood glucose levels were measured after 50 g oral glucose load and after the consumption of a portion of different foods containing 50 g of carbohydrates. We also evaluated the associations between postprandial glucose responses and the clinical characteristics of the participants at the beginning of the study. Methods: 12 healthy volunteers (age: 36 ± 17 years, BMI: 24.9 ± 3.5 kg/m²) ate white bread (WB) and whole grain (WG) bread and drank a 50 g glucose drink as reference. Postprandial glucose responses were evaluated by CGM, IV and C blood glucose measurements. Incremental area under the curve (AUCi) of postprandial blood glucose was calculated for 1 h (AUCi 0-60) and 2 h (AUCi 0-120). Results: After the consumption of white bread and whole grain bread, the AUCi 0-60 min did not differ between CGM and IV or C. AUCi 0-120 min of CGM showed no difference compared to C. Correlation analyses revealed a positive association of age with glucose AUCi 0-120 (r = 0.768; P = 0.004) and WG AUCi 0-120 (r = 0.758; P = 0.004); fasting blood glucose correlated with WG AUCi 0-120 (r = 0.838; P < 0.001). Conclusion: Despite considerable inter-individual variability of postprandial glycemic responses, CGM evaluated postprandial glycemic excursions which had comparable results compared to standard blood glucose measurements under real-life conditions. Associations of AUCi 0-60 and AUCi 0-120 postprandial glucose response with age or fasting blood glucose could be shown.
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Inoue, Yutaka, Yukari Kitani, Satoshi Osakabe, Yukitoshi Yamamoto, Isamu Murata, and Ikuo Kanamoto. "The Effects of Gold Kiwifruit Intake Timing with or without Pericarp on Postprandial Blood Glucose Level." Nutrients 13, no. 6 (June 19, 2021): 2103. http://dx.doi.org/10.3390/nu13062103.

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The purpose of this study was to examine how gold kiwifruit pericarp (pericarp is defined as the skin of the fruit) consumption and the timing thereof affect the postprandial blood glucose profile. The study was conducted on ten healthy volunteers (six men and four women). According to our results, the simultaneous intake of gold kiwifruit with bread and the prior intake of gold kiwifruit evidently suppressed the postprandial blood glucose elevation compared with exclusive bread intake. There was no significant difference in postprandial blood glucose changes between the ingestion of gold kiwifruit pericarp and pulp and that of gold kiwifruit pulp only. The highest postprandial blood glucose elevation was suppressed by 27.6% and the area under the blood glucose elevation curve by 29.3%, even with the exclusive ingestion of gold kiwifruit pulp. We predicted that the ingestion of both the pericarp and pulp of gold kiwifruit would reduce the postprandial blood glucose elevation to a greater extent than that of gold kiwifruit pulp only; however, there was no significant difference between the two. These results indicate that gold kiwifruit consumption significantly suppresses the postprandial blood glucose elevation regardless of pericarp presence or absence and the timing of ingestion.
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Takano, Akira, Tomoyasu Kamiya, Hiroshi Tomozawa, Shiori Ueno, Masahito Tsubata, Motoya Ikeguchi, Kinya Takagaki, et al. "Insoluble Fiber in Young Barley Leaf Suppresses the Increment of Postprandial Blood Glucose Level by Increasing the Digesta Viscosity." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/137871.

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Barley (Hordeum vulgareL.) is a well-known cereal plant. Young barley leaf is consumed as a popular green-colored drink, which is named “Aojiru” in Japan. We examined the effects of barley leaf powder (BLP) and insoluble fibers derived from BLP on postprandial blood glucose in rats and healthy Japanese volunteers. BLP and insoluble fibers derived from BLP suppressed the increment of postprandial blood glucose levels in rats (), and increased the viscosity of their digesta. The insoluble fibers present in BLP might play a role in controlling blood glucose level by increasing digesta viscosity. In human, BLP suppressed the increment of postprandial blood glucose level only in those which exhibited higher blood glucose levels after meals (). BLP might suppress the increment of postprandial blood glucose level by increasing digesta viscosity in both of rats and humans who require blood glucose monitoring.
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Koschinsky, Theodor, Sascha Heckermann, and Lutz Heinemann. "Parameters Affecting Postprandial Blood Glucose: Effects of Blood Glucose Measurement Errors." Journal of Diabetes Science and Technology 2, no. 1 (January 2008): 58–66. http://dx.doi.org/10.1177/193229680800200109.

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Hatamoto, Yoichi, Ryoma Goya, Yosuke Yamada, Eichi Yoshimura, Sena Nishimura, Yasuki Higaki, and Hiroaki Tanaka. "Effect of exercise timing on elevated postprandial glucose levels." Journal of Applied Physiology 123, no. 2 (August 1, 2017): 278–84. http://dx.doi.org/10.1152/japplphysiol.00608.2016.

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There is no consensus regarding optimal exercise timing for reducing postprandial glucose (PPG). The purpose of the present study was to determine the most effective exercise timing. Eleven participants completed four different exercise patterns 1) no exercise; 2) preprandial exercise (jogging); 3) postprandial exercise; and 4) brief periodic exercise intervention (three sets of 1-min jogging + 30 s of rest, every 30 min, 20 times total) in a random order separated by a minimum of 5 days. Preprandial and postprandial exercise consisted of 20 sets of intermittent exercise (1 min of jogging + 30 s rest per set) repeated 3 times per day. Total daily exercise volume was identical for all three exercise patterns. Exercise intensities were 62.4 ± 12.9% V̇o2peak. Blood glucose concentrations were measured continuously throughout each trial for 24 h. After breakfast, peak blood glucose concentrations were lower with brief periodic exercise (99 ± 6 mg/dl) than those with preprandial and postprandial exercise (109 ± 10 and 115 ± 14 mg/dl, respectively, P < 0.05, effect size = 0.517). After lunch, peak glucose concentrations were lower with brief periodic exercise than those with postprandial exercise (97 ± 5 and 108 ± 8 mg/dl, P < 0.05, effect size = 0.484). After dinner, peak glucose concentrations did not significantly differ among exercise patterns. Areas under the curve over 24 h and 2 h postprandially did not differ among exercise patterns. These findings suggest that brief periodic exercise may be more effective than preprandial and postprandial exercise at attenuating PPG in young active individuals. NEW & NOTEWORTHY This was the first study to investigate the effect of different exercise timing (brief periodic vs. preprandial vs. postprandial exercise) on postprandial glucose (PPG) attenuation in active healthy men. We demonstrated that brief periodic exercise attenuated peak PPG levels more than preprandial and postprandial exercise, particularly in the morning. Additionally, PPG rebounded soon after discontinuing postprandial exercise. Thus, brief periodic exercise may be better than preprandial and postprandial exercise at attenuating PPG levels.
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Більше джерел

Дисертації з теми "Postprandial blood glucose"

1

Amaral, Catarina Medeiros. "Effect of the ingestion of a mousse with cinnamon C. Burmannii on the postprandial blood glucose response of healthy subjects and its antioxidant power." Master's thesis, Instituto Superior de Ciências da Saúde Egas Moniz, 2013. http://hdl.handle.net/10400.26/5109.

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Dissertação para obtenção do grau de Mestre em Nutrição Clínica
Background: Cinnamon has been shown to reduce postprandial glycaemia and enhance insulin sensitivity in healthy adults.
Aims: To study the effect of C. burmannii on the postprandial blood glucose response of healthy subjects and its antioxidant capacity in a semi-solid food.
Design: Twenty four apparently healthy subjects participated in this study. They were randomly assigned in group A (reference meal) or group B (test meal). The blood glucose concentrations were measured before the ingestion of the meals and 30, 60, 90 and 120 minutes after the start of the meal. The test meal used consisted of 100 g of mousse mixed with 3 g of cinnamon.
Results: The addition of 3 g of cinnamon to the mousse had no significant effect in blood glucose response in terms of the areas under the curve (AUC) and in the different postprandial times (p>0,05). The mean Cmax was significantly lower after the ingestion of the reference meal than after the ingestion of the mousse with 3 g of C.burmannii (96 mg/dl VS 104,42 mg/dl; p=0,011). The chemical analysis showed that the mousse with 3 g of cinnamon has a much higher phenolic content and antioxidant capacity than the mousse without cinnamon.
Conclusions: The inclusion of cinnamon in the mousse increased the antioxidant capacity of this semi-solid food, however it did not reduce the postprandial glucose response in healthy subjects.
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2

Wong, Evelyn Yin-Yue. "Effect of viscosity modification by fiber dose and heat treatment on postprandial blood glucose response." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ28882.pdf.

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3

Pannoni, Nina. "The Effect of Various Carbohydrate Supplements on Postprandial Blood Glucose Response in Female Soccer Players." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3281.

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PURPOSE: The purpose of this study is to examine the effects of different types of carbohydrates on blood glucose response in collegiate soccer athletes at rest. This will help to determine the effectiveness of a carbohydrate supplement in providing sustained energy and maintained performance if ingested prior to a soccer match. METHODS: In a cross-over design, 10 female collegiate soccer players (n= 10, age 20.10 ± .99 years, height 65.55 ± 2.77 inches, weight 64.12 ± 8.36 kilograms) from the University of South Florida reported to the laboratory on five separate occasions after an overnight fast. Once a baseline blood glucose measurement was obtained, subjects ingested one of four different carbohydrate beverages (dextrose, maltodextrin, Vitargo®, and waxy maize) and a control (water). Each subject consumed 1 gram of carbohydrate per kilogram body weight in a 7% solution. Order of carbohydrate and control supplements was randomly assigned for each participant. After the subject ingested one of the test beverages blood glucose measurements were taken at the 30, 45, 60, 90, 120, and 180 minute time points (a total of three hours). The same procedures took place during each subject's visit. A series of one-way analysis of variance (ANOVA) were performed using SPSS 19 to determine differences in the blood glucose response at each time point between the carbohydrate supplements. RESULTS: No significant difference existed between treatments for blood glucose levels at baseline. At 30, 45, and 60 minutes, blood glucose concentrations following dextrose, maltodextrin, and Vitargo® ingestion were significantly higher as compared to the placebo ingestion. No significant difference was observed between waxy maize and placebo at these time points. At ninety minutes the blood glucose concentrations for dextrose and Vitargo® were significantly higher than placebo, and at 120 minutes only Vitargo® was significantly higher than the placebo. Finally, at 180 minutes, the blood glucose concentration for waxy maize was significantly higher than all other treatments. CONCLUSION: The main finding of this study was that waxy maize does not observe a sharp increase in blood glucose response following ingestion but maintains an elevated blood glucose concentration over an extended period of time. All other treatments (maltodextrin, dextrose, and Vitargo®) resulted in a significant rise in blood glucose within the first thirty minutes following ingestion.
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Mohammed, Nadia H. J. "Effect of carbohydrate source on postprandial blood glucose in subjects with type 1 diabetes using insulin lispro." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ63166.pdf.

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5

Claudia, Cecilia Yamamoto Noguchi. "Mathematical Model of Glucose-Insulin Metabolism Considering Meal Absorption Rate and Model-based Blood Glucose Control for Prandial State in Type 1 Diabetes." 京都大学 (Kyoto University), 2016. http://hdl.handle.net/2433/217171.

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Hsieh, Tsung-han. "PANCREATIC EXPRESSION OF TRPA1, ITS ROLE IN INSULIN SECRETION AND ITS POSSIBLE EFFECT ON POSTPRANDIAL BLOOD GLUCOSE LEVELS." OpenSIUC, 2013. https://opensiuc.lib.siu.edu/theses/1331.

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Анотація:
Approximately 25.8 million people, 8.3% of the population in the United States have diabetes mellitus (DM), which makes this disease one of the biggest public health problems facing this country. Type 2 diabetes (T2DM) is a heterogeneous disease characterized by variable degrees of insulin resistance, impaired insulin secretion, and increased glucose production. Currently, the insulin secretagogues known as sulfonylureas represent the major mainline drug class for long-term treatment. However, serious side effects, such as hypoglycemia and loss of potency with long-term use necessitate the development of novel insulin secretagogues. Transient receptor potential (TRP) channels have been reported to be involved in pancreatic insulin secretion. TRPA1 is a Ca2+-permeable nonselective cation channel. TRPA1 can be activated by molecules produced during oxidative glycolysis. TRPA1 may be an attractive candidate for drug development because of its involvement in the mechanism of insulin secretion. Previous studies have shown TRPA1 is expressed in rat pancreatic islets and that its activation promotes insulin release. This study was designed to determine if TRPA1 is expressed in mouse and human pancreatic β cells and whether it can promote insulin secretion. I demonstrated that TRPA1 is expressed in mouse and human pancreatic islets. I measured TRPA1-induced membrane currents using patch-clamp and used Ca2+ imaging to demonstrate that TRPA1 agonists induce Ca2+ influx in rat β cell-derived RINm5F cells. I confirmed that TRPA1 KO mice have no TRPA1 mRNA or protein in pancreatic β cells. I used isolated islet cells to demonstrate TRPA1-induced Ca2+ influx using Ca2+ imaging. By using pancreatic islets obtained from wild-type and TRPA1 KO mice, I determined that TRPA1 is important for insulin secretion. Finally, I determined that intraperitoneal administration of a TRPA1 agonist and antagonist affected blood glucose levels and plasma insulin levels in a manner consistent with the TRPA1 acting to increase insulin secretion. Furthermore, glucose tolerance was impaired in TRPA1 KO mice upon intraperitoneal glucose tolerance test (IPGTT) challenge compared to wild-type mice. In summary, I have shown TRPA1 is expressed not only in rat pancreatic islets but also in mouse and human pancreatic islets. I confirmed the localization of TRPA1 in pancreatic β cells. All of the experimental results are consistent with the concept that TRPA1 acts as to increase the insulin-secreting capacity of pancreatic β cells. According to my data, TRPA1 may play a role in promoting insulin secretion in patients with T2DM. Therefore, pharmacological activation of TRPA1 may be a novel therapeutic method for the treatment of diabetes.
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Beneyto, Tantiña Aleix. "Robust and fault-tolerant strategies for controlling blood glucose in patients with type 1 diabetes." Doctoral thesis, Universitat de Girona, 2020. http://hdl.handle.net/10803/670998.

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Type 1 diabetes is a serious disease that must be monitored and controlled artificially by supplying exogenous insulin to the body. The artificial pancreas (AP) is a closed-loop system that resulted from integrating an insulin pump with a CGM and uses a control algorithm to automate insulin infusion. In this work, a novel tuning system and a multivariable control approach are presented for an AP system aimed to be robust against patient variability, meals and exercise. To enhance safety, fault detection 2/2 strategies are also developed as an integral part of the system. The approaches have been extensively validated in simulation and in an inpatient clinical trial
La T1D és una greu que requereix de monitorització i que ha de ser controlada de forma artificial subministrant insulina exògena. El pàncrees artificial (AP) és un sistema de llaç tancat resultant d'integrar una bomba d'insulina amb un CGM, i utilitza un sistema de control per automatitzar la infusió d'insulina. En aquest treball es presenten un nou sistema d’ajust i un sistema de control de vàries variables per a sistemes AP, dissenyat per ser robust davant la variabilitat del pacient, a menjars i exercici. Per augmentar la seguretat del pacient, també es dissenyen estratègies de detecció de fallades com una part integral dels sistema. Les estratègies proposades en aquest treball han estat validades extensivament en simulació i durant un assaig clínic, amb resultats prometedors
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8

García, Jaramillo Maira Alejandra. "Prediction of postprandial blood glucose under intra-patient variability and uncertainty and its use in the design of insulin dosing strategies for type 1 diabetic patients." Doctoral thesis, Universitat de Girona, 2011. http://hdl.handle.net/10803/52564.

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Анотація:
In this thesis I propose a novel method to estimate the dose and injection-to-meal time for low-risk intensive insulin therapy. This dosage-aid system uses an optimization algorithm to determine the insulin dose and injection-to-meal time that minimizes the risk of postprandial hyper- and hypoglycaemia in type 1 diabetic patients. To this end, the algorithm applies a methodology that quantifies the risk of experiencing different grades of hypo- or hyperglycaemia in the postprandial state induced by insulin therapy according to an individual patient’s parameters. This methodology is based on modal interval analysis (MIA). Applying MIA, the postprandial glucose level is predicted with consideration of intra-patient variability and other sources of uncertainty. A worst-case approach is then used to calculate the risk index. In this way, a safer prediction of possible hyper- and hypoglycaemic episodes induced by the insulin therapy tested can be calculated in terms of these uncertainties.
En esta tesis se propone un nuevo método para estimar la dosis y el instante de inyección que genere el menor riesgo para una terapia intensiva de insulina. El sistema de dosificación utiliza un algoritmo de optimización para determinar la dosis de insulina y el instante de inyección que reduzcan al máximo el riesgo de hiperglucemia e hipoglucemia posprandial en pacientes diabéticos tipo 1. Para ello, el algoritmo aplica una metodología que cuantifica el riesgo de sufrir diferentes grados de hipoglucemia e hiperglucemia en estado postprandial inducida por la terapia de insulina de acuerdo a los parámetros de cada paciente. Aplicando análisis intervalar modal se predice el nivel de glucosa postprandial considerando la variabilidad intrapaciente y otras fuentes de incertidumbre. Con un planteamiento del peor caso se calcula una predicción más segura de posibles episodios de hiperglucemia e hipoglucemia inducida por la terapia de insulina en términos de dichas incertidumbres.
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9

Oviedo, Castillo Silvia. "Forecasting and decision support for type 1 diabetes insulin therapy using machine learning." Doctoral thesis, Universitat de Girona, 2019. http://hdl.handle.net/10803/667332.

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Анотація:
Insulin therapy for Type 1 Diabetes (T1D) has several ramifications with different degrees of automation. The advances in sensors and monitoring devices have led to an increasing availability of data. Additionally, machine learning algorithms usage has sprung, allowing the development of models for Blood Glucose (BG) forecasting with relative ease. Nevertheless, BG forecasting is still a challenging task for prediction horizons beyond 30 min and, even more so, with missing or erroneous data, which is a common burden in the field. This thesis is devoted to generate machine learning models that forecast either BG levels using regression algorithms or postprandial hypoglycemia using classification algorithms. The application of these models range from Multiple Daily Injections (MDI) therapy up to Sensor Augmented Pump (SAP) therapy.
La teràpia amb insulina per a pacients amb T1D tenen vàries ramificacions amb diferents graus d’automatització. Els avenços en sensors i dispositius de monitorització comporten un increment en la disponibilitat de dades. A més a més, l’ús d’algoritmes d’aprenentatge automàtic s’han popularitzat, facilitant així el desenvolupament de models per pronosticar Glucosa en Sang (GS) amb major facilitat. No obstant això, preveure els nivells de GS és una tasca complexa per a finestres de predicció més enllà de 30 minuts, i més encara, amb dades errònies o absents, la qual cosa és una limitació molt freqüent en aquest camp. Aquesta tesis està dedicada a la generació de models basats en aprenentatge automàtic per predir ja siguin nivells de GS utilitzant algoritmes de regressió o hipoglucèmia postprandial utilitzant algoritmes de classificació. L’aplicació d’aquests models van des de la teràpia de múltiples injeccions diàries (MID), fins a la teràpia SAP
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10

"Matcha Tea and its Acute Effects on Postprandial Blood Glucose." Master's thesis, 2018. http://hdl.handle.net/2286/R.I.49415.

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abstract: ABSTRACT Many natural interventions have been effective at lowering postprandial glucose concentrations (PPG) in research trials and, theoretically, should have favorable effects on the prevention and management of T2DM. Natural interventions include vinegar, nuts and exercise. Green tea has been demonstrated to also possessing antiglycemic effects. Thus, green tea, and its most abundant catechin EGCG, are being consumed for its potential health benefits in cancer prevention and in its inhibitory effects on α-amylase. Many studies have found EGCG to inhibit α-amylase an enzyme needed in the breakdown of carbohydrates (CHO). Other studies have looked at EGCG and its potential for lowering PPG concentrations due to its inhibitory effects on α-amylase in both mice and humans. Yet there is no research on Matcha tea specifically. Matcha tea is green tea in powder form; hence, it is consumed in its entirety unlike traditional teas which are steeped in bags. The purpose of this study was to determine whether Macha tea impacts PPG concentrations in healthy adults. Twelve subjects completed this randomized controlled, single blinded, crossover study. On three separate occasions the twelve subjects consumed a bagel and jam with either water, Lipton green tea, or Macha tea. Fasting blood glucose was taken upon their arrival. Once the tea or water and bagel with jam were consumed PPG concentrations were measured every 30 minutes until 120 minutes were reached. Results showed no statistically significant effects on PPG concentrations in either test groups (p=.960). However, this study did not measure EGCG levels in the tea provided. Therefore, further research should be done with known EGCG amounts to see its effects on PPG concentrations to fully rule out its potential.
Dissertation/Thesis
Masters Thesis Nutrition 2018
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Книги з теми "Postprandial blood glucose"

1

Wong, Evelyn Yin-Yue. Effect of viscosity modification by fiber dose and heat treatment on postprandial blood glucose response. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1999.

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2

Mohammed, Nadia H. J. Effect of carbohydrate source on postprandial blood glucose in subjects with type 1 diabetes using insulin lispro. Ottawa: National Library of Canada, 2001.

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3

Lebovitz, Harold E., and Shlomo Ben-Haim. Novel technologies: What does gastric electrical stimulation offer to the patient with type 2 diabetes and depression? Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198789284.003.0014.

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Owing to the epidemiologic dimensions of type 2 diabetes, obesity, and depression, the development of novel and effective treatment options for these conditions is of great importance. One of the major challenges in this field is that many antidiabetic and antidepressive drugs may have disadvantageous metabolic effects by increasing weight and worsening insulin resistance. Novel technologies more effectively considering the pathophysiological changes related to this entity are needed. The DIAMOND electrical stimulation device improves glycaemic control, causes weight loss and decreases systolic blood pressure in overweight and obese patients with type 2 diabetes. The DIAMOND device detects food ingestion and automatically activates its postprandial metabolic effects. It does so with minimal side effects, no hypoglycaemia, modest weight loss, minimal requirement for self-blood glucose monitoring, and improvement in eating behaviour. The properties of DIAMOND treatment suggest that it may have merit for treating patients with comorbid diabetes and depression.
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Частини книг з теми "Postprandial blood glucose"

1

Numao, Shigeharu. "Role of Physical Exercise on Postprandial Blood Glucose Responses to Low-Carbohydrate/High-Fat Diet Intake." In Physical Activity, Exercise, Sedentary Behavior and Health, 151–63. Tokyo: Springer Japan, 2015. http://dx.doi.org/10.1007/978-4-431-55333-5_13.

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2

Kobori, Masuko, Risa Araki, and Koichi Hashimoto. "Health Functions of Fermented Soybean Product Natto: Poly-Gamma-Glutamic Acid Reduces the Postprandial Blood Glucose Levels." In ACS Symposium Series, 87–99. Washington, DC: American Chemical Society, 2022. http://dx.doi.org/10.1021/bk-2022-1430.ch008.

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3

Martini, Santi, Hermina Novida, and Kuntoro. "Infarct Stroke and Blood Glucose Associated with Food Consumption in Indonesia." In Cerebrovascular Diseases [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.101548.

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Stroke is the primary cause of death in adults. It is predicted that the death caused by stroke will increase twice in the next 30 years. In Indonesia, stroke is one of the diseases of the circulatory system, which has been taking the first place of causing death since 2007. Indonesia has rice as the main type of daily food consumed, which has higher glycemic index than other sources. This study aims to find the risk of blood glucose level that determines the incidence of infarct stroke. There were 164 patients enrolled in this study, 82 patients in each stroke and not stroke group. The blood examination is using the enzymatic method, which is the hexokinase method. The results of research revealed that indicators of high blood glucose level were found in infract stroke incidence, including casual blood glucose, fasting blood glucose, 2-h postprandial blood glucose, and glycated hemoglobin. These four indicators were found in a higher level in the infarct stroke than the non-stroke group. Other epidemiological studies have shown that diabetes is a risk factor for stroke. Therefore, education about food selection should be a priority in the effort to prevent infarct stroke and diabetes mellitus in Indonesia.
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4

Lema-Pérez, Laura. "Main Organs Involved in Glucose Metabolism." In Sugar Intake - Risks and Benefits and the Global Diabetes Epidemic. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.94585.

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Sugar, or technically known as glucose, is the main source of energy of all cells in the human body. The glucose homeostasis cycle is the mechanism to maintain blood glucose levels in a healthy threshold. When this natural mechanism is broken, many metabolic disorders appear such as diabetes mellitus, and some substances of interest, like glucose, are out of control. In the mechanism to maintain blood glucose, several organs are involved but the role of most of them has been disregarded in the literature. In this chapter, the main organs involved in such a mechanism and their role in glucose metabolism are described. Specifically, the stomach and small intestine, organs of the gastrointestinal system, are the first to play an important role in the regulatory system, because it is where carbohydrates are digested and absorbed as glucose into the bloodstream. Then glucose as a simple substance goes to the liver to be stored as glycogen. Glucose storage occurs due to the delivery of hormones from the pancreas, which produces, stores, and releases insulin and glucagon, two antagonistic hormones with an important role in glucose metabolism. The kidneys assist the liver in insulin clearance in the postprandial state and gluconeogenesis in the post absorptive state. Physiological aspects and the detailed role of every organ involved in glucose metabolism are described in this chapter.
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5

Kimura, Toshiyuki. "Development of Mulberry Leaf Extract for Suppressing Postprandial Blood Glucose Elevation." In Hypoglycemia - Causes and Occurrences. InTech, 2011. http://dx.doi.org/10.5772/24893.

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6

Salam, Muhammad, and James Sowers. "Case 84: Postprandial Hypoglycemia, an Uncommon Presentation of Type 2 Diabetes." In Diabetes Case Studies: Real Problems, Practical Solutions, 311–13. American Diabetes Association, 2015. http://dx.doi.org/10.2337/9781580405713.84.

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A 52-year-old white man presented to his primary care physician with neurogenic symptoms (sweating, palpitations, headache) accompanied by capillary blood glucose levels in the 40–60 mg/dL range. The symptoms would always occur 1–2 h after a meal and would resolve with ingestion of a sugar source (e.g., orange juice, regular soda). There was no history of neuroglycopenic symptoms (confusion, loss of consciousness, seizure) during any of these episodes. Patient’s prior history was notable for hypertension, hyperlipidemia, and gastroesophageal reflux disease (GERD). Physical examination was remarkable for central obesity with a BMI of 32 kg/m2.
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7

Magar, Maria, Anne Peters, and Braden Barnett. "Case 34: Hyperinsulemic Hypoglycemia After Roux-en-Y Gastric Bypass Surgery: Both Fasting and Postprandial." In Diabetes In Practice: Case Studies with Commentary, 143–45. American Diabetes Association, 2021. http://dx.doi.org/10.2337/9781580407663.34.

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The case subject is a 34-year-old female with a past history of Roux-en-Y gastric bypass (RYGB) surgery for obesity (BMI 41 kg/m2). Two years after the RYGB, now with BMI of 24.9 kg/m2, she started having symptomatic hypoglycemia, nausea, and vomiting. An inpatient 72-h fast was negative, but she experienced a drop in her blood glucose (BG) from 20 to 50 mg/dL, with concurrent loss of consciousness after eating a mixed meal.
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8

"Mechanism of the Inhibition by Chlorogenic Acids against Postprandial Increase in Blood Glucose Level." In Green Coffee Bean Extract in Human Health, 89–101. Taylor & Francis Group, 6000 Broken Sound Parkway NW, Suite 300, Boca Raton, FL 33487-2742: CRC Press, 2016. http://dx.doi.org/10.1201/9781315371153-6.

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Тези доповідей конференцій з теми "Postprandial blood glucose"

1

Rozier, Eric W. D. "Fraise: A framework for predicting peak postprandial blood glucose using personalized data-driven modeling." In 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2017. http://dx.doi.org/10.1109/bibm.2017.8217809.

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2

Zhang, Ying, Xiyang Zhang, Zhifang Li, and Hui Li. "In vivo noninvasive measurement of preprandial and postprandial blood glucose using optical coherence tomography." In SPIE/COS Photonics Asia, edited by Qingming Luo, Xingde Li, Ying Gu, and Yuguo Tang. SPIE, 2016. http://dx.doi.org/10.1117/12.2245683.

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3

Hashimoto, Shogo, Claudia Cecilia Yamamoto Noguchi, and Eiko Furutani. "Postprandial blood glucose control in type 1 diabetes for carbohydrates with varying glycemic index foods." In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2014. http://dx.doi.org/10.1109/embc.2014.6944706.

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4

Moravek, D., AM Duncan, MD Loreto, FL Pals-Horne, PK Lukus, A. Hawke, M. Aliani, and DD Ramdath. "Substituting Wheat Flour with Lentils in a Muffin Matrix Reduces Postprandial Blood Glucose in Healthy Adults." In Abstracts of the NHPRS – The 15th Annual Meeting of the Natural Health Products Research Society of Canada (NHPRS). Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1644942.

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5

Ogawa, Rio, Sunao Kotani, Kazumi Ninomiya, Shigenobu Ina, Hitoshi Kumagai, Chiaki Sugimoto, Yusuke Yamaguchi, and Hitomi Kumagai. "Examination of an efficient extraction method for rice-bran albumin and its suppressive effect on postprandial blood glucose elevation." In Virtual 2021 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2021. http://dx.doi.org/10.21748/am21.596.

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6

Ogawa, Rio, Hitomi Kumagai, Sébastien Paul, and Yusuke Yamaguchi. "Physicochemical properties of buckwheat albumin." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/huin2273.

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Анотація:
For prevention of diabetes mellitus, it is effective to suppress or retard the increase in postprandial blood glucose level. We have already shown that buckwheat albumin inhibits α-amylase and suppresses postprandial hyperglycaemia even after the hydrolysis by digestive enzymes. However, there is no detailed report on the functional properties of buckwheat albumin for its industrial use. In this study, we evaluated emulsifying and foaming properties of buckwheat albumin before and after proteolytic hydrolysis in addition to the thermal stability.Thermal stability of buckwheat albumin was measured as the residual α-amylase inhibitory activity after heating at 100°C for 10–120 min. For the evaluation of emulsifying and foaming properties, buckwheat albumin and its hydrolysates were dissolved in citrate-phosphate buffer at pH 3–6. Emulsifying property was evaluated as the turbidity of emulsion 0–30 min after homogenization of the sample solution with corn oil. Foaming property was measured as foam volume of the sample solution 0–30 min after whipping with a household type mixer. Foaming and emulsifying properties of egg albumin were also measured for comparison. As a result, buckwheat albumin showed high thermal resistance even after boiling for 120 min. Buckwheat albumin showed higher emulsifying and foaming properties than egg albumin in the pH range of 3-6. Although proteolytic hydrolysis reduced emulsifying property of buckwheat albumin, it retained high foaming property. These findings suggest that buckwheat albumin can be applied not only for a functional food material to prevent diabetes but also for a texture improver for bakery products such as bread and cakes.
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