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Статті в журналах з теми "PLUMBAGIN ZEYLANICA"
Purwoko, Mitayani, Harijono Kario Sentono, Bambang Purwanto, and Dono Indarto. "Phytochemical evaluation of Plumbago zeylanica roots from Indonesia and assessment of its plumbagin concentration." Folia Medica 64, no. 1 (February 28, 2022): 96–102. http://dx.doi.org/10.3897/folmed.64.e58086.
Повний текст джерелаDubey, Nidhi, Nitin Dubey, Rajendra Mehta, and Ajay Kumar Saluja. "Determination of Psoralen and Plumbagin from Its Polyherbal Oil Formulations by an HPTLC Densitometric Method." Journal of AOAC INTERNATIONAL 92, no. 3 (May 1, 2009): 779–84. http://dx.doi.org/10.1093/jaoac/92.3.779.
Повний текст джерелаFerreira, G. M., and K. S. Laddha. "A METHOD FOR PREPARATION OF DROSERONE FROM PLUMBAGIN." INDIAN DRUGS 50, no. 05 (May 28, 2013): 53–56. http://dx.doi.org/10.53879/id.50.05.p0053.
Повний текст джерелаFerreira, G. M., and K. S. Laddha. "A METHOD FOR PREPARATION OF DROSERONE FROM PLUMBAGIN." INDIAN DRUGS 50, no. 05 (May 28, 2013): 53–56. http://dx.doi.org/10.53879/id.50.05.p0053.
Повний текст джерелаAdusei, Emmanuel B. A., Reimmel K. Adosraku, James Oppong-Kyekyeku, and Cedric D. K. Amengor. "Investigation of Acid-Base Indicator Property of Plumbagin from Plumbago zeylanica Linn." International Journal of Analytical Chemistry 2019 (August 18, 2019): 1–13. http://dx.doi.org/10.1155/2019/4061927.
Повний текст джерелаPhuong, Nguyen Tran Dong, and Tran Thi Xuan Huong. "Effect of natural auxin from portulaca grandiflora hook and Ipomoea batatas (L.) Poir on the formation adventitious roots in vitro of Plumbago zeylanica L." ENGINEERING AND TECHNOLOGY 8, no. 2 (June 4, 2020): 30–37. http://dx.doi.org/10.46223/hcmcoujs.tech.en.8.2.344.2018.
Повний текст джерелаSu, Yan, Mao Li, Qi Wang, Xingfeng Xu, Peifang Qin, Haitao Huang, Yuting Zhang, Yali Zhou та Jianguo Yan. "Inhibition of the TLR/NF-κB Signaling Pathway and Improvement of Autophagy Mediates Neuroprotective Effects of Plumbagin in Parkinson’s Disease". Oxidative Medicine and Cellular Longevity 2022 (22 грудня 2022): 1–14. http://dx.doi.org/10.1155/2022/1837278.
Повний текст джерелаAleem, Mohd. "Anti-Inflammatory and Anti-Microbial Potential of Plumbago zeylanica L.: A Review." Journal of Drug Delivery and Therapeutics 10, no. 5-s (October 15, 2020): 229–35. http://dx.doi.org/10.22270/jddt.v10i5-s.4445.
Повний текст джерелаRajbhar, Karishma, Jasvinder Kaushal, Himanshu Dawda, and Usha Mukundan. "QUANTIFICATION OF LEAF AND ROOT PLUMBAGIN IN PLUMBAGO ZEYLANICA FOLLOWED BY A COMPARATIVE STUDY WITH CALLUS AND COMMERCIAL SOURCE." Journal of Advanced Scientific Research 13, no. 02 (March 31, 2022): 202–6. http://dx.doi.org/10.55218/jasr.202213229.
Повний текст джерелаPatel, Hetal D., Ramar Krishnamurthy, and Musibau A. Azeez. "Effect of Biofertilizer on Growth, Yield and Bioactive Component of Plumbago zeylanica (Lead Wort)." Journal of Agricultural Science 8, no. 5 (April 13, 2016): 141. http://dx.doi.org/10.5539/jas.v8n5p141.
Повний текст джерелаДисертації з теми "PLUMBAGIN ZEYLANICA"
Nguyen, Anh Tho. "Structure elucidation and biological evaluation of cytotoxic constituents isolated from three Vietnamese medicinal plants :Plumbago Zeylanica, Scrophularia Ningpoensis and Disporopsis Aspera." Doctoral thesis, Universite Libre de Bruxelles, 2005. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210998.
Повний текст джерелаROY, ARPITA. "BIOTECHNOLOGICAL APPROACHES FOR THE PRODUCTION OF PLUMBAGIN FROM PLUMBAGO ZEYLANICA." Thesis, 2020. http://dspace.dtu.ac.in:8080/jspui/handle/repository/18075.
Повний текст джерелаHsieh, Yen-Ju, and 謝硯如. "Herbal analysis of plumbagin content in Plumbago zeylanica L. and its pharmacokinetics in rats." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/67603226326872277118.
Повний текст джерела國立陽明大學
傳統醫藥學研究所
97
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) is an herbal ingredient which is isolated from the root of Plumbago zeylanica L. In previous reports, there is information on the separations of plumbagin from P. zeylanica L. and its analytical method. Also in recent years, some studies investigated pharmacological functions such as anti-cancer, anti-inflammation and central nervous system effects. However, the absorption, distribution, metabolism, and elimination of plumbagin are still unknown. First of all, a reliable liquid chromatography coupled with tandem mass spectrometric (LC-MS/MS) method was developed to determine the contents of plumbagin from P. zeylanica L. Secondly, an automated blood sampling system for serial blood sampling from conscious and freely moving rats coupled with LC-MS/MS method was used to evaluate the oral bioavailability of plumbagin. Thirdly, microdialysis sampling techniques coupled with high performance liquid chromatography and ultraviolet spectrometry was developed to simultaneously assess the unbound plumbagin in rat blood and bile. Moreover, the roles of P-glycoprotein transport and glucuronidation metabolism on the pharmacokinetics of plumbagin were also estimated by using cyclopsorin A and probenecid to inhibit respective pathways. Finally, the elimination of plumbagin in urine and feces were measured to determine the unabsorbed part and possible metabolites of plumbagin after oral administration. The results indicate that mass fractions of plumbagin in Plumbago zeylanica L. for H2O, 50 % ethanol (v/v) and 95 % ethanol (v/v) were 0.2 ± 0.04, 3.9 ± 0.71 and 13.4 ± 1.30 g/kg, respectively. The oral bioavailability of plumbagin was 38.7 ± 5 %. Unbound plumbagin appeared in blood and bile microdialysate. The AUC of plumbagin in blood and bile were 59.9 ± 7.1 and 31.2 ± 1.8 min・µg/mL, respectively. Furthermore, the bile-to-blood distribution ratio (AUCbile/AUCblood) of plumbagin was 1.7. These results suggest that plumbagin can be excreted in the bile. In combination with P-glycoprotein inhibitor, the concentration of plumbagin in bile declined, but not in blood. This data supports the idea that excretion of plumbagin in bile is regulated by P-glycoprotein. In combination with glucuronidation inhibitor, the concentration of plumbagin in bile increased, but not in blood. The result supports that plumbagin excreted through the glucuronidation pathway. 49.2 % of plumbagin appeared in feces within 84 hours, and 12 % of plumbagin appeared in urine 120 hours after oral administration, approximately. Furthermore, possible metabolites of plumbagin were found in rat urine and they were produced by the metabolism of plumbagin in liver with phase I aliphatic hydroxylation (MW 203) and phase II glucuronidation (MW 363 and 539) in urine, as identified by LC-MS/MS. In conclusion, this study developed a reliable LC-MS/MS to determine the absorption, distribution, metabolism and elimination of plumbagin in the rat. Herbal analysis of Plumbago zeylanica L. and pharmacokinetics of plumbagin will provide some valuable information for future clinical application.
THAKRAN, NEERU. "ESTIMATION OF PLUMBAGIN BY RP-HPLC & FAME ANALYSIS BY GC-MS OF IMPORTANT MEDICINAL PLANT PLUMBAGO ZEYLANICA." Thesis, 2016. http://dspace.dtu.ac.in:8080/jspui/handle/repository/15047.
Повний текст джерелаRASTOGI, ANSHIKA. "BIOTIC ELICITORS USED TO ENHANCE PLUMBAGIN PRODUCTION IN PLUMBAGO ZEYLANICA AND ASSESMENT OF ANTIOXIDANT AND ANTIBACTERIAL ACTIVITY." Thesis, 2020. http://dspace.dtu.ac.in:8080/jspui/handle/repository/18363.
Повний текст джерелаHuang, Tung-Liang, and 黃棟樑. "Studies of anti-Helicobacter pylori activity of Plumbago zeylanica Linn., a Taiwanese folk medicinal plant." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/39249470664857591359.
Повний текст джерела國立中興大學
食品科學系
92
Helicobacter pylori has been verified to be strongly correlated to gastric cancer and peptic ulceration. The most effective and famous treatment for H. pylori is a triple therapy, which combines two antibiotics with either an acid suppressor or a stomach lining protector. However, resistance to some antibiotics became a problem due to the frequently use of antibiotics. In this study, first, ethanol extracts of fifty Taiwanese folk medicinal plants were screened for their anti-H. pylori activity. Five herbs, Plumbago zeylanica Linn. (PZL), Paederia scandens Mer, Anisomeles indica (L.) O. Kuntze, Alpinia speciosa (Wendl.) K. Schum. and Bombax malabaricum DC., showed strong anti-H. pylori activity. Twenty six herbs including Artemisia argvi Levl. et Vant, Bidens bipinnata L., Bletilla formosana (Hayata) Schltr, Chenopodium ambrosioides L., Canarium album (Lour.) Raeuschel, Centella asiatica (L.) Urban., Ehretia acuminata R. Br., Houttuynia cordata Thunb., Litsea cubeba (Lour.) Persoon, Ludwigia octovalvis (Jacq.) Raven., Melastoma candidum D. Don, Polygonum chinense Linn., Psidium guajava L., Phyla nodiflora (Linn.) Greene, Polygonum senticosum (Meissn) Franch. et Sav., Rhus semialata Merr. var. roxburghiana DC, Sonchus arvensis Linn., Sphenomeris chusana (L.) Copel, Sambucus chinensis Lindl., Setaria palmfolia Stapf, Senecio scandens Buch-Ham., Tridax procumbens L. , Vernonia cinerea (L.) Less., Wikstroemia indica (L.) C. A. Mey, Xanthium strumarium Linn., and Zanthoxylum nitidum (Roxb.) DC. showed moderate anti-H. pylori activity. The other nineteen herbs including Areca catechu Linn., Agrimonia pilosa Ledeb., Amaranthus spinosus L., Amaranthus virdis L., Bischofia javanica Blume, Bidens pilosa L. var. minor (Blume) Sherff, Cayratia japonica (Thunb.) Gagnep., Catharanthus roseus (L.) G. Don., Cycas revoluta Thunb., Euphorbia hirta Linn., Flemingia philippinensis Merr. & Rolfe, Gnaphalium adnatum Wall. ex DC., Hibiscus muthtabilis Linn., Milletia reticulata Bentham, Phyllanthus urinaria Linn., Sophora flavescens Ait., Solanum nigrum Linn., Sida rhombifolia Linn., and Viola mandshurica only showed low anti-H. pylori activity. PZL, which showed the strongest anti-H. pylori activity in the primary screening, was selected as study material , and the anti-H. pylori activities of PZL extracts were discussed in this study. PZL is a plant that grows throughout Asia and Africa. The whole plant and its roots have been used as a folk medicine for the treatment of rheumatic pain, dysmenorrhea, carbuncle, coutusion of extremities, ulcers, and killing intestinal parasites in Taiwan. To test the anti-H. pylori activity of PZL, four kinds of extracts were prepared to test on five H. pylori strains. Water and the organic solvents such as ethanol, acetone and ethyl acetate were used for PZL extraction. The ethyl acetate extract showed greatest anti-H. pylori activaty and lowest minimum inhibitory concentrations (MICs) (0.32 mg/mL ~ 1.28 mg/mL). Bactericidal activities were observed on the ethyl acetate, acetone and ethanol extracts studies. The ascending order of minimum bactericidal concentration (MBCs) was ethyl acetate, acetone, and ethanol extracts, and bactericidal activities were appeared to be dose dependent. The bactericidal activity observed on the ethyl acetate extract acted over a wide pH range (pH 2-7). The anti-H. pylori activity wouldn’t be affected by pH, even pretreating the ethyl acetate extract in pH 1-7 buffer for 2 hours wouldn’t affected its anti-H. pylori activity. According to the literatures, the major ingredient, plumbagin, derived from the roots of PLZ was a naphthoquinone compound. In this study, plumbagin also observed to have strong anti-H. pylori activity. A High-performance Liquid Chromatography (HPLC) assay was developed and validated for the quantitative analysis of plumbagin of PZL. The reverse-phase HPLC was performed by using a gradient mobile phase composing water and methanol, and peaks were detected at 254 nm (ultraviolet detection). Standard curves were linearized in the range from 10 to 200 g/mL (regression coefficient r2 = 0.99995). After spiked 50, 100, and 150 g/mL of plumbagin standard solution, the recoveries were between 97.45 % and 99.24 %. Both the intra-day and inter-day precision (RSD) were found less than 1 % coefficient variation at concentrations of 50, 100, and 150 g/mL. The detection and quantitation limits were 210-4 and 610-4 g, respectively. Based on the validation results, the analytical method showed to be a precise, accurate and stable method to quantify plumbagin of PZL.
Chen, Yi-Chun, and 陳怡君. "Regulation of Proliferation and Cytokine Genes Expression in Human Peripheral Blood Mononuclear Cells by Bioactive Components from Plumbago zeylanica." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/36227376478546430081.
Повний текст джерела國立陽明大學
藥理學研究所
91
Action mechanisms of elliptinone (C22H14O6; M.W. 374), xanthyletin (C14H12O3; M.W. 228), xanthoxyletin (C15H14O4; M.W. 258), seselin (C14H12O3; M.W. 228), 5-methoxyseselin (C15H14O4; M.W. 258), and suberosin (C15H16O3; M.W. 244) isolated from Plumbago zeylanica on phytohemagglutinin (PHA) stimulated cell proliferation were studied in primary culture of human peripheral blood mononuclear cells (PBMCs). The results demonstrated that these components suppressed PBMCs proliferation, at about 0 to 24 hr after stimulation with PHA. Cell cycle analysis indicated that elliptinone, xanthyletin, xanthoxyletin, seselin, 5-methoxyseselin, and suberosin arrested the cell cycle progression of activated PBMCs from the G1 transition to the S phase. To further localize the point in the cell cycle at which arrest occurred, a set of key regulatory events leading to the G1/S boundary, including the expression and production of cyclins and cytokines, activation of NF-AT and NF-κB, mobilization of intracellular Ca2+ ([Ca2+]i), and phosphorylation of mitogen-activated protein (MAP) kinases, were examined. These compounds suppressed, in activated PBMCs lymphocytes, the production and mRNA expression of interleukin-2 (IL-2) and interferon-γ (IFN-γ). The levels of Cyclin D3 and Cyclin E proteins in PBMCs stimulated with PHA were reduced by subersoin. Both 5-methoxyseselin and suberosin impaired the production of Cyclin A in activated PBMCs. Results of confocal microscopy analysis indicated that the translocation of the NF-AT and NF-κB in PBMCs induced by PHA were suppressed by 5-methoxyseselin and suberosin. Furthermore, 5-methoxyseselin and suberosin reduced [Ca2+]i in activated PBMCs. The phosphorylation of extracellular-signal regulated kinase (ERK) protein in activated PBMCs stimulated with PHA was attenuated by 5-methoxyseselin and suberosin. Thus, the suppressant effects of 5-methoxyseselin and suberosin on proliferation of PBMCs activated by PHA appeared to be mediated, at least in part, through reduction of [Ca2+]i , ERK kinases activation and early genes expression in PBMCs, especially those of important cyclins, IL-2, and IFN-γ, and arresting cell cycle progression in the cells.
Частини книг з теми "PLUMBAGIN ZEYLANICA"
Dev, Sukh. "Plumbago zeylanica." In Prime Ayurvedic Plant Drugs, 564–70. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-22075-3_81.
Повний текст джерелаKhare, C. P. "Plumbago zeylanica Linn." In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_1235.
Повний текст джерелаAkbar, Shahid. "Plumbago zeylanica L. (Plumbaginaceae)." In Handbook of 200 Medicinal Plants, 1475–83. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-16807-0_152.
Повний текст джерелаRussell, Scott D. "Biphasic pollen tube growth in Plumbago zeylanica." In Biotechnology and Ecology of Pollen, 385–90. New York, NY: Springer New York, 1986. http://dx.doi.org/10.1007/978-1-4613-8622-3_62.
Повний текст джерелаBloch, Khalida, Vijay Singh Parihar, Minna Kellomäki, and Sougata Ghosh. "Natural Compounds from Plumbago zeylanica as Complementary and Alternative Medicine." In Handbook of Oxidative Stress in Cancer: Therapeutic Aspects, 415–42. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-5422-0_33.
Повний текст джерелаBloch, Khalida, Vijay Singh Parihar, Minna Kellomäki, and Sougata Ghosh. "Natural Compounds from Plumbago zeylanica as Complementary and Alternative Medicine." In Handbook of Oxidative Stress in Cancer: Therapeutic Aspects, 1–28. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-1247-3_33-1.
Повний текст джерела"Chitrak (Plumbago zeylanica)." In Rasayana, 114–15. CRC Press, 2002. http://dx.doi.org/10.1201/b12602-41.
Повний текст джерелаTripathi, M. K., G. Tiwari, Sushma Tiwari, Niraj Tripathi, Mohini Sharma, Shashank Bhargav, S. L. Patidar, and Sharad Tiwari. "Influence of Plant Growth Regulators on In vitro Morphogenesis in Plumbago Zeylanica Linn." In Research Aspects in Biological Science Vol. 7, 96–123. Book Publisher International (a part of SCIENCEDOMAIN International), 2022. http://dx.doi.org/10.9734/bpi/rabs/v7/3679a.
Повний текст джерела