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Готові списки джерел за темами / Pleurotus ostreatus Lectin / Статті в журналах

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Статті в журналах з теми "Pleurotus ostreatus Lectin"

Автор: Grafiati

Опубліковано: 11 березня 2023

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1

Chattopadhyay, T. K., J. N. Lisgarten, R. Brechtel, H. Rüdiger, and R. A. Palmer. "Crystallization of Pleurotus ostreatus (oyster mushroom) lectin." Acta Crystallographica Section D Biological Crystallography 55, no. 9 (September 1, 1999): 1589–90. http://dx.doi.org/10.1107/s0907444999007945.

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Анотація:

Crystals of Pleurotus ostreatus (oyster mushroom) lectin have been grown by the hanging-drop technique using ammonium sulfate as the precipitant at 293 K. Over a period of between two and three weeks, crystals of hexagonal bipyramidal morphology grew to maximum dimensions of 0.2 × 0.2 × 0.5 mm. The crystals belong to space group P6122 or P6522, with unit-cell parameters a = b = 155.9, c = 149.8 Å, V = 3153078 Å3, Z = 12 (assuming 50% solvent), and diffract to 4.1 Å at 293 K.

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2

Perduca, Massimiliano, Laura Destefanis, Michele Bovi, Monica Galliano, Francesca Munari, Michael Assfalg, Fabio Ferrari, Hugo L. Monaco, and Stefano Capaldi. "Structure and properties of the oyster mushroom (Pleurotus ostreatus) lectin." Glycobiology 30, no. 8 (January 27, 2020): 550–62. http://dx.doi.org/10.1093/glycob/cwaa006.

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Abstract Pleurotus ostreatus Lectin (POL) is a 353 amino acid chain lectin that can be purified from the fruiting bodies of the very well-known and widely diffused edible oyster mushrooms (P. ostreatus). The lectin has been partially characterized by different groups and, although it was crystallized about 20 years ago, its 3D structure and the details of its interactions with carbohydrates are still unknown. This paper reports the 3D structure and ligand-binding properties of POL. We have determined the X-ray structure of the apo-protein purified from the fruiting bodies of the mushroom and that of the recombinant protein in complex with melibiose to a resolution of about 2 Å. The lectin is a homodimer in which the two polypeptide chains are linked by a disulfide bridge. A POL monomer is composed of two highly homologous β-jellyroll domains each of which containing a calcium-dependent carbohydrate-binding site. A high degree of sequence similarity is observed between the two carbohydrate-binding modules present in each monomer. The structure of the lectin in complex with melibiose reveals that a POL dimer has four calcium-dependent carbohydrate-binding sites. The interaction with sugars in solution has been characterized by isothermal titration calorimetry and saturation transfer difference NMR and it sheds new light on the molecular determinants of POL specificity. The lectin exhibits in vitro antiproliferative effects against human cancer cell lines and presents structural similarity with the prototype member of the CBM67 family, the noncatalytic domain of Streptomyces avermitilis α-rhamnosidase.

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3

Elhusseiny, Shaza M., Taghrid S. El-Mahdy, Mohamed F. Awad, Nooran S. Elleboudy, Mohamed M. S. Farag, Mahmoud A. Yassein, and Khaled M. Aboshanab. "Proteome Analysis and In Vitro Antiviral, Anticancer and Antioxidant Capacities of the Aqueous Extracts of Lentinula edodes and Pleurotus ostreatus Edible Mushrooms." Molecules 26, no. 15 (July 30, 2021): 4623. http://dx.doi.org/10.3390/molecules26154623.

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In this study, we examined aqueous extracts of the edible mushrooms Pleurotus ostreatus (oyster mushroom) and Lentinula edodes (shiitake mushroom). Proteome analysis was conducted using LC-Triple TOF-MS and showed the expression of 753 proteins by Pleurotus ostreatus, and 432 proteins by Lentinula edodes. Bioactive peptides: Rab GDP dissociation inhibitor, superoxide dismutase, thioredoxin reductase, serine proteinase and lectin, were identified in both mushrooms. The extracts also included promising bioactive compounds including phenolics, flavonoids, vitamins and amino acids. The extracts showed promising antiviral activities, with a selectivity index (SI) of 4.5 for Pleurotus ostreatus against adenovirus (Ad7), and a slight activity for Lentinula edodes against herpes simplex-II (HSV-2). The extracts were not cytotoxic to normal human peripheral blood mononuclear cells (PBMCs). On the contrary, they showed moderate cytotoxicity against various cancer cell lines. Additionally, antioxidant activity was assessed using DPPH radical scavenging, ABTS radical cation scavenging and ORAC assays. The two extracts showed potential antioxidant activities, with the maximum activity seen for Pleurotus ostreatus (IC50 µg/mL) = 39.46 ± 1.27 for DPPH; 11.22 ± 1.81 for ABTS; and 21.40 ± 2.20 for ORAC assays. This study encourages the use of these mushrooms in medicine in the light of their low cytotoxicity on normal PBMCs vis à vis their antiviral, antitumor and antioxidant capabilities.

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4

Conrad, Fritz, and Harold Rüdiger. "The lectin from Pleurotus ostreatus: Purification, characterization and interaction with a phosphatase." Phytochemistry 36, no. 2 (May 1994): 277–83. http://dx.doi.org/10.1016/s0031-9422(00)97061-4.

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5

Devi, K. Sanjana P., Bibhas Roy, Pradip Patra, Banalata Sahoo, Syed S. Islam, and Tapas K. Maiti. "Characterization and lectin microarray of an immunomodulatory heteroglucan from Pleurotus ostreatus mycelia." Carbohydrate Polymers 94, no. 2 (May 2013): 857–65. http://dx.doi.org/10.1016/j.carbpol.2013.02.017.

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6

Kawagishi, Hirokazu, Hiroshi Suzuki, Haruki Watanabe, Hiroko Nakamura, Takehiko Sekiguchi, Takeomi Murata, Taichi Usui, et al. "A lectin from an edible mushroom Pleurotus ostreatus as a food intake-suppressing substance." Biochimica et Biophysica Acta (BBA) - General Subjects 1474, no. 3 (May 2000): 299–308. http://dx.doi.org/10.1016/s0304-4165(00)00027-1.

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7

Kobayashi, Yuka, Hiroko Nakamura, Takehiko Sekiguchi, Ryo Takanami, Takeomi Murata, Taichi Usui, and Hirokazu Kawagishi. "Analysis of the carbohydrate binding specificity of the mushroom Pleurotus ostreatus lectin by surface plasmon resonance." Analytical Biochemistry 336, no. 1 (January 2005): 87–93. http://dx.doi.org/10.1016/j.ab.2004.09.029.

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8

Wang, Hexiang, Jiquan Gao, and T. B. Ng. "A New Lectin with Highly Potent Antihepatoma and Antisarcoma Activities from the Oyster Mushroom Pleurotus Ostreatus." Biochemical and Biophysical Research Communications 275, no. 3 (September 2000): 810–16. http://dx.doi.org/10.1006/bbrc.2000.3373.

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9

M. Kamel, Ismail, Neveen M. Khalil, Sherien M.M. Atalla, and Sara S.M. Seleem. "PURIFICATION, MOLECULAR AND BIOCHEMICAL CHARACTERIZATION AND BIOLOGICAL APPLICATIONS OF HEMAGGLUTINATING LECTIN WITH ANTICANCER ACTIVITIES FROM PLEUROTUS OSTREATUS." PLANT ARCHIVES 21, Suppliment-1 (January 15, 2021): 416–31. http://dx.doi.org/10.51470/plantarchives.2021.v21.s1.065.

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10

Vajravijayan, S., S. Pletnev, Z. Luo, V. Z. Pletnev, N. Nandhagopal, and K. Gunasekaran. "Crystallographic and calorimetric analysis on Pleurotus ostreatus lectin and its sugar complexes - promiscuous binding driven by geometry." International Journal of Biological Macromolecules 152 (June 2020): 862–72. http://dx.doi.org/10.1016/j.ijbiomac.2020.02.294.

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11

Yokoyama, Sumie, Hiroko Nakamura, and Sinji Tokuyama. "A Lectin from the Edible and Medicinal Mushroom Pleurotus ostreatus (Jacq.: Fr.) Kumm. as a Food Intake Suppressing Substance." International Journal of Medicinal Mushrooms 3, no. 2-3 (2001): 1. http://dx.doi.org/10.1615/intjmedmushr.v3.i2-3.850.

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12

Brechtel, Rolf, Hermann Wätzig та Harold Rüdiger. "The lectin from the mushroom Pleurotus ostreatus: a phosphatase-activating protein that is closely associated with an α-galactosidase activity". Plant Science 160, № 5 (квітень 2001): 1025–33. http://dx.doi.org/10.1016/s0168-9452(01)00349-1.

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13

Bulam, Sanem, Nebahat Şule Üstün, and Aysun Pekşen. "Evaluation of Nutritional and Medicinal Values of Edible Wild and Cultivated Pleurotus ostreatus." Turkish Journal of Agriculture - Food Science and Technology 7, no. 12 (December 13, 2019): 2054. http://dx.doi.org/10.24925/turjaf.v7i12.2054-2061.2730.

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Анотація:

Because of its high nutritional value and pharmaceutical effects, oyster mushroom (Pleurotus ostreatus (Jacq. ex Fr.) P. Kumm.) is collected from nature and cultivated in large scale. This therapeutic mushroom is consumed as a functional food or food additive in soups, cereal and dairy products, and commercially used in nutraceuticals and dietary supplements. The mycochemicals including polysaccharides (crude fiber and β-glucans), essential amino acids, ergothioneine, peptides, (glyco)proteins, lectins, phenolic compounds, polyketides (lovastatin), (tri)terpenoids, and enzymes are naturally found in the fruiting bodies and mycelial biomass of P. ostreatus. The major bioactive compounds concentration of this mushroom may be increased by modification of the substrate composition and cultivation or postharvest conditions. The goal of this review is to evaluate the results of the studies about the biochemical composition and medicinal properties of edible wild and cultivated P. ostreatus. Furthermore, the advanced novel cultivation techniques, biotechnological processes, and postharvest treatments were given in order to increase its nutritional and nutraceutical values.

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14

Brechtel, Rolf, Hermann Wätzig та Harold Rüdiger. "Erratum to “The lectin from the mushroom Pleurotus ostreatus: a phosphatase-activating protein that is closely associated with an α-galatosidase activity A part of this paper has been presented as a preliminary report at the 17th Interlec. Meeting 1997 in Würzburg, Germany”". Plant Science 161, № 4 (вересень 2001): 821. http://dx.doi.org/10.1016/s0168-9452(01)00506-4.

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15

Talkad, Muralidhar S., Rajat K. Das, Preetham Bhattacharjee, Sagnik Ghosh, and Undre Prasad Shivajirao. "Establishment of Enzyme Inhibitory Activities of Lovastatin, Isolated From Pleurotus ostreatus." International Journal of Applied Sciences and Biotechnology 3, no. 3 (September 25, 2015): 408–16. http://dx.doi.org/10.3126/ijasbt.v3i3.12932.

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Enzyme inhibition is significant biological process to characterize the enzyme reaction, extraction of catalysis parameters in bio-industry and bioengineering. The enzyme inhibitors are low molecular weight chemical compounds. Inhibitor can modify one amino acid, or several side chain(s) required in enzyme catalytic activity. To protect enzyme catalytic site from any change, ligand binds with critical side chain in enzyme. Safely, chemical modification can be done to test inhibitor for any drug value. In the present day world they are known for culinary values due to their high-quality proteins, vitamins, fibers and many medicinal properties and accordingly they are called nutraceuticals. Overproduction of ROS can damage cellular biomolecules like nucleic acids, proteins, lipids, carbohydrates, proteins and enzymes resulting in several diseases. The chemical nature of the bioactive compounds present in this mushroom includes: polysaccharides, lipopolysaccharides, proteins, peptides, glycoproteins, lectins, lipids and their derivatives. We report the presence of Statins in fruiting bodies and fermentation processes from Pleurotus ostreatus. Lovastatin extracted from the Pleurotus ostreatus showed Anti-oxidant Activity when compared with Standard Quercetin, IC50 values of 3.5?g/ml and 7.5 ?g/ml respectively, amylase Assay the percentage inhibitions of 35% and 70 % with 1 and 3 mg/ml respectively. In Membrane Stability assay, the percentage inhibitions of 47.06% and 50%. Acid Phosphatase Assay: percentage inhibitions of 82.78% and 76.11% with 2mg/ml and 4mg/ml respectively. Pleurotus possess a good antioxidant and enzyme inhibitions for Alpha Amylase, Acid Phosphatase and membrane stability studies, hence as health promoter and environmental restorer is gaining more importance.Int J Appl Sci Biotechnol, Vol 3(3): 408-416

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16

Xu, Danyun, Jing Lu, Yuanyuan Wang, Aafaque Ahmed Keerio, Liesheng Zheng, Liguo Chen, and Aimin Ma. "Identification and In Silico Analysis of Lectins in Gray Oyster Culinary-Medicinal Mushroom Pleurotus ostreatus (Agaricomycetes) Based on the Transcriptomes." International Journal of Medicinal Mushrooms 21, no. 12 (2019): 1193–205. http://dx.doi.org/10.1615/intjmedmushrooms.2019032886.

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17

Davitashvili, Elene, Ekaterine Kapanadze, Eva Kachlishvili, Eka Metreveli, and Vladimir Elisashvili. "Comparative Study of the Hemagglutinating Activity of Lectins Isolated from Different Developmental Stages of Culinary-Medicinal Oyster Mushroom, Pleurotus ostreatus (Jacq.: Fr.) Kumm. (Agaricomycetideae)." International Journal of Medicinal Mushrooms 12, no. 1 (2010): 43–50. http://dx.doi.org/10.1615/intjmedmushr.v12.i1.40.

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18

Wal, Pranay, Jyotsana Dwivedi, Shivangi Kushwaha, Anil Yadav, Shashi Pratap Singh, and K. Joshi Hanumanthachar. "A Comprehensive review on Nutritional and Medicinal properties of Pleurotus ostreatus: An Oyster Mushroom." Current Nutrition & Food Science 18 (September 1, 2022). http://dx.doi.org/10.2174/1573401318666220901144438.

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Abstract: Mushrooms are an important aspect of the human diet, and their popularity has increased over the years. Pleurotus ostreatus (P. ostreatus) are the most commonly consumed mushrooms by the rural dwellers in South Western Nigeria, perhaps, based on their nutritive value and health-enhancing benefits. Pleurotus is a genus of about 40 mushroom species popularly referred to as "oyster mushrooms." P. ostreatus is one of several Pleurotus species that are widely consumed for their flavour, nutritional value, and medicinal properties. Polysaccharides, proteins, peptides, triterpenoids, lectins, lipids, and their derivatives are all found in the P. ostreatus mushroom, in addition to its essential therapeutic components. P. ostreatus commonly consumed as food or as food supplement have been reported in folklore for their antihypertensive property with limited scientific proof. This review emphasizes the excellent nutritional value of P. ostreatus mushrooms.

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19

Elhusseiny, Shaza M., Taghrid S. El-Mahdy, Nooran S. Elleboudy, Mohamed M. S. Farag, Khaled M. Aboshanab, and Mahmoud A. Yassien. "Immunomodulatory activity of extracts from five edible basidiomycetes mushrooms in Wistar albino rats." Scientific Reports 12, no. 1 (July 20, 2022). http://dx.doi.org/10.1038/s41598-022-16349-2.

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AbstractMushrooms are nutritious foods that are widely cultivated all over the world. They are rich in a range of compounds linked to improving functions of the immune system including carotenoids, alkaloids, lectins, enzymes, folates, fats, organic acids, minerals, polysaccharides, phenolics, proteins, tocopherols, terpenoids, and volatile compounds. In this study we investigated, the immunomodulatory activity in rats of the aqueous extracts of five of the most common edible mushrooms belonging to Family Basidiomycota-white-rot fungi including, Lentinula edodes, Agaricus bisporus, Pleurotus ostreatus, Pleurotus columbinus, and Pleurotus sajor-caju. Male Wistar albino rats were assigned to thirteen groups and Immunosuppression was induced by oral administration of dexamethasone (0.1 mg/kg), followed by oral administration of the mushroom extracts at low (200 mg/kg) and high (400 mg/kg) doses. A positive control group received the immune stimulant Echinacea extract Immulant® at (30 mg/kg), while the negative control group received only saline. From each animal, in each group, blood samples were collected after 15 days for complete blood counts and for measurement of immunologic parameters, including lysozyme activity, nitric oxide (NO) production and serum cytokines including tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ) and interleukin 1 beta (IL-1β) levels. Results have shown that white blood cells (WBCs) and lymphocytic counts were significantly boosted by high doses of each of the five mushroom extracts (207–289% increase for WBC and 153–175% for lymphocytes) with a significant increase in lysozyme activity (110–136% increase), NO concentration (159–232% increase) and cytokines as compared to the negative control group. Histopathological examination of the rats' spleen and thymus tissues has shown marked lymphocytic proliferation that was more obvious at the higher doses. In conclusion, our results showed that the five edible mushroom extracts revealed significant immunostimulatory effects preclinically particularly, at the higher doses (400 mg/kg) which can be considered the effective dose.

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