Статті в журналах з теми "PKM1/PKM2"
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Li, Lin, Siyuan Cheng, and Xiuping Yu. "The expression of PKM1 and PKM2 in benign and cancerous prostatic tissues." Journal of Clinical Oncology 41, no. 16_suppl (June 1, 2023): e17058-e17058. http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e17058.
Kim, Seong Ho, Ji Hun Wi, HyeRan Gwak, Eun Gyeong Yang, and So Yeon Kim. "Single-Cell FISH Analysis Reveals Distinct Shifts in PKM Isoform Populations during Drug Resistance Acquisition." Biomolecules 12, no. 8 (August 6, 2022): 1082. http://dx.doi.org/10.3390/biom12081082.
Verbrugge, Sander A. J., Sebastian Gehlert, Lian E. M. Stadhouders, Daniel Jacko, Thorben Aussieker, Gerard M. J. de Wit, Ilse S. P. Vogel, et al. "PKM2 Determines Myofiber Hypertrophy In Vitro and Increases in Response to Resistance Exercise in Human Skeletal Muscle." International Journal of Molecular Sciences 21, no. 19 (September 25, 2020): 7062. http://dx.doi.org/10.3390/ijms21197062.
Buneeva, Olga, Arthur Kopylov, Oksana Gnedenko, Marina Medvedeva, Alexander Veselovsky, Alexis Ivanov, Victor Zgoda, and Alexei Medvedev. "Proteomic Profiling of Mouse Brain Pyruvate Kinase Binding Proteins: A Hint for Moonlighting Functions of PKM1?" International Journal of Molecular Sciences 24, no. 8 (April 21, 2023): 7634. http://dx.doi.org/10.3390/ijms24087634.
Kurihara-Shimomura, Miyako, Tomonori Sasahira, Chie Nakashima, Hiroki Kuniyasu, Hiroyuki Shimomura, and Tadaaki Kirita. "The Multifarious Functions of Pyruvate Kinase M2 in Oral Cancer Cells." International Journal of Molecular Sciences 19, no. 10 (September 25, 2018): 2907. http://dx.doi.org/10.3390/ijms19102907.
Williams, Allison Lesher, Vedbar Khadka, Mingxin Tang, Abigail Avelar, Kathryn J. Schunke, Mark Menor, and Ralph V. Shohet. "HIF1 mediates a switch in pyruvate kinase isoforms after myocardial infarction." Physiological Genomics 50, no. 7 (July 1, 2018): 479–94. http://dx.doi.org/10.1152/physiolgenomics.00130.2017.
Lee, Yuumi, Yuko Ito, Kohei Taniguchi, Takashi Nuri, SangWoong Lee, and Koichi Ueda. "Experimental Study of Warburg Effect in Keloid Nodules: Implication for Downregulation of miR-133b." Plastic and Reconstructive Surgery - Global Open 11, no. 8 (August 2023): e5202. http://dx.doi.org/10.1097/gox.0000000000005202.
Kuranaga, Yuki, Nobuhiko Sugito, Haruka Shinohara, Takuya Tsujino, Kohei Taniguchi, Kazumasa Komura, Yuko Ito, Tomoyoshi Soga, and Yukihiro Akao. "SRSF3, a Splicer of the PKM Gene, Regulates Cell Growth and Maintenance of Cancer-Specific Energy Metabolism in Colon Cancer Cells." International Journal of Molecular Sciences 19, no. 10 (October 2, 2018): 3012. http://dx.doi.org/10.3390/ijms19103012.
Xia, Yong, Xing Wang, Yan Liu, Ellen Shapiro, Herbert Lepor, Moon-Shong Tang, Tung-Tien Sun, and Xue-Ru Wu. "PKM2 Is Essential for Bladder Cancer Growth and Maintenance." Cancer Research 82, no. 4 (December 13, 2021): 571–85. http://dx.doi.org/10.1158/0008-5472.can-21-0403.
Grant, Melissa M. "Pyruvate Kinase, Inflammation and Periodontal Disease." Pathogens 10, no. 7 (June 22, 2021): 784. http://dx.doi.org/10.3390/pathogens10070784.
Lemos, Fernanda O., Ian de Ridder, Martin D. Bootman, Geert Bultynck, and Jan B. Parys. "The Complex Effects of PKM2 and PKM2:IP3R Disruption on Intracellular Ca2+ Handling and Cellular Functions." Cells 12, no. 21 (October 26, 2023): 2527. http://dx.doi.org/10.3390/cells12212527.
Mojzeš, Anamarija, Marko Tomljanović, Lidija Milković, Renata Novak Kujundžić, Ana Čipak Gašparović, and Koraljka Gall Trošelj. "Cell-Type Specific Metabolic Response of Cancer Cells to Curcumin." International Journal of Molecular Sciences 21, no. 5 (February 28, 2020): 1661. http://dx.doi.org/10.3390/ijms21051661.
Huang, Rong, Rong Han, Yucheng Yan, Jifan Yang, Guoxuan Dong, Miao Wang, Zhiguo Su, Hu Jiao, and Jincai Fan. "PTB Regulates the Metabolic Pathways and Cell Function of Keloid Fibroblasts through Alternative Splicing of PKM." International Journal of Molecular Sciences 24, no. 6 (March 8, 2023): 5162. http://dx.doi.org/10.3390/ijms24065162.
Nayak, Manasa, Nirav Dhanesha, Manish Jain, and Anil Chauhan. "Manipulating Metabolic Plasticity By Targeting Pyruvate Kinase M2 in Platelets Inhibits Arterial Thrombosis." Blood 132, Supplement 1 (November 29, 2018): 868. http://dx.doi.org/10.1182/blood-2018-99-112704.
Goldberg, Michael S., and Phillip A. Sharp. "Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression." Journal of Experimental Medicine 209, no. 2 (January 23, 2012): 217–24. http://dx.doi.org/10.1084/jem.20111487.
Ensink, Elliot, and Sophia Y. Lunt. "Abstract 3031: Impact of pyruvate kinase isoforms on cysteine metabolism in pancreatic cancer." Cancer Research 82, no. 12_Supplement (June 15, 2022): 3031. http://dx.doi.org/10.1158/1538-7445.am2022-3031.
Warenius, Hilmar M. "Selectively depleting the energy of cancer cells: A new therapeutic paradigm." Journal of Cancer Biology 5, no. 1 (January 29, 2024): 1–10. http://dx.doi.org/10.46439/cancerbiology.5.057.
Bluemlein, Katharina, Nana-Maria Grüning, René G. Feichtinger, Hans Lehrach, Barbara Kofler, and Markus Ralser. "No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis." Oncotarget 2, no. 5 (May 22, 2011): 393–400. http://dx.doi.org/10.18632/oncotarget.278.
Wang, Ying-Hua, William J. Israelsen, Dongjun Lee, Vionnie W. C. Yu, Nathaniel T. Jeanson, Clary B. Clish, Lewis C. Cantley, Matthew G. Vander Heiden, and David T. Scadden. "Differential Dependence On Aerobic Glycolysis In Normal and Malignant Hematopoietic Stem and Progenitor Cells To Sustain Daughter Cell Production." Blood 122, no. 21 (November 15, 2013): 793. http://dx.doi.org/10.1182/blood.v122.21.793.793.
Nayak, Manasa K., Madankumar Ghatge, Nirav Dhanesha, Gagan D. Flora, Manish Jain, Omar Rodriguez, Kathleen Markan, Mathhhew Potthoff, Steven R. Lentz, and Anil K. Chauhan. "Targeting Metabolic Enzyme Pyruvate Kinase M2: A Novel Strategy to Inhibit Platelet Function and Arterial Thrombosis." Blood 134, Supplement_1 (November 13, 2019): 1056. http://dx.doi.org/10.1182/blood-2019-129027.
Shi, Weiye, Xu Yao, Xueyu Cao, Yu Fu, and Yingze Wang. "Serine/Arginine-Rich Splicing Factor 7 Knockdown Inhibits Aerobic Glycolysis and Growth in HepG2 Cells by Regulating PKM2 Expression." Current Issues in Molecular Biology 46, no. 5 (May 20, 2024): 5023–36. http://dx.doi.org/10.3390/cimb46050301.
Taniguchi, Kohei, Nobuhiko Sugito, Minami Kumazaki, Haruka Shinohara, Nami Yamada, Yoshihito Nakagawa, Yuko Ito, et al. "MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer." Cancer Letters 363, no. 1 (July 2015): 17–27. http://dx.doi.org/10.1016/j.canlet.2015.03.026.
Yan, Qiuxia, Peng Zeng, Xiuqin Zhou, Xiaoying Zhao, Runqiang Chen, Jing Qiao, Ling Feng, Zhenjie Zhu, Guozhi Zhang, and Cairong Chen. "RBMX suppresses tumorigenicity and progression of bladder cancer by interacting with the hnRNP A1 protein to regulate PKM alternative splicing." Oncogene 40, no. 15 (February 9, 2021): 2635–50. http://dx.doi.org/10.1038/s41388-021-01666-z.
Sturgill, Eric M., and Monica L. Guzman. "Cytokine Induced Nuclear Localization Of Pyruvate Kinase M2 In Acute Myeloid Leukemia." Blood 122, no. 21 (November 15, 2013): 5406. http://dx.doi.org/10.1182/blood.v122.21.5406.5406.
Sun, Ye, Yushi Chen, Ming Xu, Chunying Liu, Hai Shang, and Chun Wang. "Shenmai Injection Supresses Glycolysis and Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant A549/DDP Cells via the AKT-mTOR-c-Myc Signaling Pathway." BioMed Research International 2020 (June 22, 2020): 1–10. http://dx.doi.org/10.1155/2020/9243681.
Chiavarina, Barbara, Diana Whitaker-Menezes, Ubaldo E. Martinez-Outschoorn, Agnieszka K. Witkiewicz, Ruth Birbe, Anthony Howell, Richard G. Pestell, et al. "Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth." Cancer Biology & Therapy 12, no. 12 (December 15, 2011): 1101–13. http://dx.doi.org/10.4161/cbt.12.12.18703.
Akbar Napitupulu, Alief, Ni Nyoman Puspawati, and I. Desak Putu Kartika Pratiwi. "CEMARAN ASPERGILLUS FLAVUS PENGHASIL AFLATOKSIN B1 PADA JAGUNG MANIS (ZEA MAYS SACCARATA) YANG DIJUAL DI PASAR TRADISIONAL DAN PASAR MODERN DI KECAMATAN DENPASAR BARAT, KOTA MADYA DENPASAR – BALI." Jurnal Ilmu dan Teknologi Pangan (ITEPA) 7, no. 2 (July 29, 2018): 11. http://dx.doi.org/10.24843/itepa.2018.v07.i02.p02.
Bartyś, Natalia, Anna Pasternak, and Jolanta Lisowiec-Wąchnicka. "Optimization of Bifunctional Antisense Oligonucleotides for Regulation of Mutually Exclusive Alternative Splicing of PKM Gene." Molecules 27, no. 17 (September 3, 2022): 5682. http://dx.doi.org/10.3390/molecules27175682.
Balakumbahan, R., C. Ravindran, and V. Sivakumar. "Standardization of Propagation Techniques in Annual Moringa (Moringa oleifera Lam.) for Enhancing Crop Uniformity." Journal of Advances in Biology & Biotechnology 27, no. 7 (July 2, 2024): 1315–20. http://dx.doi.org/10.9734/jabb/2024/v27i71093.
Singh, Smriti, Sathiya Pandi Narayanan, Kajal Biswas, Amit Gupta, Neha Ahuja, Sandhya Yadav, Rajendra Kumar Panday, Atul Samaiya, Shyam K. Sharan, and Sanjeev Shukla. "Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect." Proceedings of the National Academy of Sciences 114, no. 43 (October 9, 2017): 11440–45. http://dx.doi.org/10.1073/pnas.1708447114.
Li, Yuchao, Shuwei Zhang, Yuexian Li, Junchao Liu, Qian Li, Wenli Zang, and Yaping Pan. "The Regulatory Network of hnRNPs Underlying Regulating PKM Alternative Splicing in Tumor Progression." Biomolecules 14, no. 5 (May 9, 2024): 566. http://dx.doi.org/10.3390/biom14050566.
FOSTER, HANNAH R., THUONG HO, EVGENIY POTAPENKO, SOPHIE L. LEWANDOWSKI, SOPHIA SDAO, HALENA R. VANDEUSEN, REBECCA L. CARDONE, RICHARD KIBBEY, and MATTHEW J. MERRINS. "127-OR: In Vivo Genetic Evidence That the Pyruvate Kinase Isoforms PKM1 and PKM2 Differentially Control Beta-Cell Fuel Sensing." Diabetes 70, Supplement 1 (June 2021): 127—OR. http://dx.doi.org/10.2337/db21-127-or.
Méndez-Lucas, Andrés, Xiaolei Li, Junjie Hu, Li Che, Xinhua Song, Jiaoyuan Jia, Jingxiao Wang, et al. "Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities." Cancer Research 77, no. 16 (June 19, 2017): 4355–64. http://dx.doi.org/10.1158/0008-5472.can-17-0498.
Dogsom, Oyungerel, Amir Hamza, Shohel Mahmud, Jung-Ki Min, Yoon-Beom Lee, and Jae-Bong Park. "The Complex of p-Tyr42 RhoA and p-p65/RelA in Response to LPS Regulates the Expression of Phosphoglycerate Kinase 1." Antioxidants 12, no. 12 (December 8, 2023): 2090. http://dx.doi.org/10.3390/antiox12122090.
Li, Dongliang, Yan Xie, Jisan Sun, Li Zhang, and Wentao Jiang. "LncRNA ZNF674-AS1 Hinders Proliferation and Invasion of Hepatic Carcinoma Cells through the Glycolysis Pathway." Journal of Oncology 2022 (July 13, 2022): 1–9. http://dx.doi.org/10.1155/2022/8063382.
Li, Qi, Xin Qi, and Wenjun Jia. "3,3′,5-triiodothyroxine inhibits apoptosis and oxidative stress by the PKM2/PKM1 ratio during oxygen-glucose deprivation/reperfusion AC16 and HCM-a cells." Biochemical and Biophysical Research Communications 475, no. 1 (June 2016): 51–56. http://dx.doi.org/10.1016/j.bbrc.2016.05.030.
Clear, Andrew James, Annalisa D'Avola, Samir G. Agrawal, Laura Z. Rassenti, Thomas J. Kipps, John G. Gribben, and John Riches. "B-Cell Receptor Signaling Drives Glycolysis in Chronic Lymphocytic Leukemia Cells." Blood 132, Supplement 1 (November 29, 2018): 3121. http://dx.doi.org/10.1182/blood-2018-99-112860.
Kabir, Mohammad Faujul, Adam Karami, Anbin Mu, Don-Gerard Conde, and Kelly A. Whelan. "Abstract 5808: Diclofenac inhibits esophageal cancer cell growth by depleting mitochondrial functions." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5808. http://dx.doi.org/10.1158/1538-7445.am2022-5808.
Park, Bohye, Ji Yeon Kim, Olivia F. Riffey, Presley Dowker-Key, Antje Bruckbauer, James McLoughlin, Ahmed Bettaieb, and Dallas R. Donohoe. "Pyruvate kinase M1 regulates butyrate metabolism in cancerous colonocytes." Scientific Reports 12, no. 1 (May 24, 2022). http://dx.doi.org/10.1038/s41598-022-12827-9.
Li, Lin, Siyuan Cheng, Yunshin Yeh, Yingli Shi, Nikayla Henderson, David Price, Xin Gu, and Xiuping Yu. "The expression of PKM1 and PKM2 in developing, benign, and cancerous prostatic tissues." Frontiers in Oncology 14 (April 12, 2024). http://dx.doi.org/10.3389/fonc.2024.1392085.
Davidson, Shawn M., Daniel R. Schmidt, Julia E. Heyman, James P. O'Brien, Amy C. Liu, William J. Israelsen, Talya L. Dayton, et al. "Pyruvate kinase M1 suppresses development and progression of prostate adenocarcinoma." Cancer Research, May 18, 2022. http://dx.doi.org/10.1158/0008-5472.can-21-2352.
Olea‐Flores, Monserrat, Tapan Sharma, Odette Verdejo‐Torres, Imaru DiBartolomeo, Paul R. Thompson, Teresita Padilla‐Benavides, and Anthony N. Imbalzano. "Muscle‐specific pyruvate kinase isoforms, PKM1 and PKM2, regulate mammalian SWI/SNF proteins and histone 3 phosphorylation during myoblast differentiation." FASEB Journal 38, no. 11 (June 4, 2024). http://dx.doi.org/10.1096/fj.202400784r.
McNally, Lindsey A., Parul Mehra, Andrew Gibb, Kenneth Brittian, Anna Gumpert, Sujith Dassanayaka, Steven P. Jones, and Bradford G. Hill. "Abstract 14268: PKM2 to PKM1 Isoform Switching in Fibroblasts Attenuates Cardiac Dysfunction in Infarcted Mice." Circulation 144, Suppl_1 (November 16, 2021). http://dx.doi.org/10.1161/circ.144.suppl_1.14268.
Yu, Lei, Shao Thing Teoh, Elliot Ensink, Martin P. Ogrodzinski, Che Yang, Ana I. Vazquez, and Sophia Y. Lunt. "Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells." Cancer & Metabolism 7, no. 1 (December 2019). http://dx.doi.org/10.1186/s40170-019-0205-z.
FOSTER, HANNAH R., THUONG HO, EVGENIY POTAPENKO, REBECCA L. CARDONE, RICHARD KIBBEY, and MATTHEW J. MERRINS. "316-OR: Genetic Deletion of Beta-Cell Pkm1, Pkm2, and Pck2 Identifies PEP as an Essential Signal for Compartmentalized KATP Closure and Cycling of the Insulin Secretory Pathway." Diabetes 71, Supplement_1 (June 1, 2022). http://dx.doi.org/10.2337/db22-316-or.
Foster, Hannah R., Thuong Ho, Evgeniy Potapenko, Sophia M. Sdao, Shih Ming Huang, Sophie L. Lewandowski, Halena R. VanDeusen та ін. "β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveal their essential role as nutrient sensors for the KATP channel". eLife 11 (23 серпня 2022). http://dx.doi.org/10.7554/elife.79422.
He, Shuo, Yan Liang, Yiyi Tan, Qing Liu, Tao Liu, Xiaomei Lu, and Shutao Zheng. "Positioning determines function: Wandering PKM2 performs different roles in tumor cells." Cell Biology International, November 17, 2023. http://dx.doi.org/10.1002/cbin.12103.
"Pyruvate kinase M2 isozyme (PKM2); PKM1." Science-Business eXchange 6, no. 3 (January 2013): 54. http://dx.doi.org/10.1038/scibx.2013.54.
Yadav, Sandhya, Somnath D. Bhagat, Amit Gupta, Atul Samaiya, Aasheesh Srivastava, and Sanjeev Shukla. "Dietary-phytochemical mediated reversion of cancer-specific splicing inhibits Warburg effect in head and neck cancer." BMC Cancer 19, no. 1 (November 1, 2019). http://dx.doi.org/10.1186/s12885-019-6257-1.
Lee, Katie C., Allison L. Williams, and Ralph V. Shohet. "Abstract 10730: Pkm2 Ablation Dysregulates Cardiac Glucose Metabolism in Mice." Circulation 146, Suppl_1 (November 8, 2022). http://dx.doi.org/10.1161/circ.146.suppl_1.10730.