Добірка наукової літератури з теми "Pharmacoepigenetic"
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Статті в журналах з теми "Pharmacoepigenetic"
Cacabelos, Ramón. "The PharmacoEpiGenetic Connection." Current Pharmacogenomics and Personalized Medicine 17, no. 2 (October 28, 2020): 72–75. http://dx.doi.org/10.2174/187569211702200921093217.
Повний текст джерелаKaraglani, Makrina, Georgia Ragia, Maria Panagopoulou, Ioanna Balgkouranidou, Evangelia Nena, George Kolios, Nikolaos Papanas, Vangelis Manolopoulos, and Ekaterini Chatzaki. "Search for Pharmacoepigenetic Correlations in Type 2 Diabetes Under Sulfonylurea Treatment." Experimental and Clinical Endocrinology & Diabetes 127, no. 04 (February 2, 2018): 226–33. http://dx.doi.org/10.1055/s-0043-121265.
Повний текст джерелаYahaya, M. A. F., S. Z. I. Zolkiffly, M. A. M. Moklas, H. Abdul Hamid, J. Stanslas, M. Zainol, and M. Z. Mehat. "Possible Epigenetic Role of Vitexin in Regulating Neuroinflammation in Alzheimer’s Disease." Journal of Immunology Research 2020 (March 10, 2020): 1–7. http://dx.doi.org/10.1155/2020/9469210.
Повний текст джерелаSun, Yan, and Robert Davis. "Rapid Collection of Biospecimens by Automated Identification of Patients Eligible for Pharmacoepigenetic Studies." Journal of Personalized Medicine 3, no. 4 (September 26, 2013): 263–74. http://dx.doi.org/10.3390/jpm3040263.
Повний текст джерелаIngelman-Sundberg, Magnus, Sarah C. Sim, Alvin Gomez, and Cristina Rodriguez-Antona. "Influence of cytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects." Pharmacology & Therapeutics 116, no. 3 (December 2007): 496–526. http://dx.doi.org/10.1016/j.pharmthera.2007.09.004.
Повний текст джерелаGomez, Alvin, and Magnus Ingelman-Sundberg. "Pharmacoepigenetic aspects of gene polymorphism on drug therapies: effects of DNA methylation on drug response." Expert Review of Clinical Pharmacology 2, no. 1 (January 2009): 55–65. http://dx.doi.org/10.1586/17512433.2.1.55.
Повний текст джерелаKhatami, Fatemeh, Mohammad R. Mohajeri-Tehrani, and Seyed M. Tavangar. "The Importance of Precision Medicine in Type 2 Diabetes Mellitus (T2DM): From Pharmacogenetic and Pharmacoepigenetic Aspects." Endocrine, Metabolic & Immune Disorders - Drug Targets 19, no. 6 (September 3, 2019): 719–31. http://dx.doi.org/10.2174/1871530319666190228102212.
Повний текст джерелаCacabelos, Ramón, Juan Carril, Natalia Cacabelos, Aleksey Kazantsev, Alex Vostrov, Lola Corzo, Pablo Cacabelos, and Dmitry Goldgaber. "Sirtuins in Alzheimer’s Disease: SIRT2-Related GenoPhenotypes and Implications for PharmacoEpiGenetics." International Journal of Molecular Sciences 20, no. 5 (March 12, 2019): 1249. http://dx.doi.org/10.3390/ijms20051249.
Повний текст джерелаLucafò, Marianna, Daria Sicari, Andrea Chicco, Debora Curci, Arianna Bellazzo, Alessia Di Silvestre, Chiara Pegolo, et al. "miR-331-3p is involved in glucocorticoid resistance reversion by rapamycin through suppression of the MAPK signaling pathway." Cancer Chemotherapy and Pharmacology 86, no. 3 (August 10, 2020): 361–74. http://dx.doi.org/10.1007/s00280-020-04122-z.
Повний текст джерелаCacabelos, Ramon. "Pharmacogenomics of Cognitive Dysfunction and Neuropsychiatric Disorders in Dementia." International Journal of Molecular Sciences 21, no. 9 (April 26, 2020): 3059. http://dx.doi.org/10.3390/ijms21093059.
Повний текст джерелаДисертації з теми "Pharmacoepigenetic"
Chu, Shih-Kai, and 朱是鍇. "Interethnic DNA Methylation Difference and its Implications in Pharmacoepigenetics." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/4t2br8.
Повний текст джерела國立陽明大學
生物醫學資訊研究所
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Using DNA methylation variants for evaluating the drug response and absorption, distribution, metabolism, and excretion (ADME) represents a crucial application in pharmacoepigenetics. However, the influence of the interethnic DNA methylation difference on the application in pharmacoepigenetics has not been studied systematically. In this dissertation, we analyzed the whole DNA methylome and RNA transcriptome data of primary tumor tissues of four cancer types (breast, colon, head and neck, and uterine corpus) from The Cancer Genome Atlas and lymphoblastoid cell lines from the International HapMap Project for African and European ancestry populations. The methylation data were generated by the Infinium HumanMethylation450 BeadChip and the gene expression data by RNA sequencing experiments. After data quality control, regression analyses with batch effect and covariate adjustments identified 307–20,287 ethnicity-associated CpG sites (E-CpGs) in the five datasets. E-CpG sites exhibited similar methylation patterns in the two studied populations; however, the patterns differed between tumor tissues and lymphoblastoid cell lines. E-CpG sites showed tumor-specific patterns of methylation and gene regulation. In addition, we observed that 264 E-CpG sites were associated with the drug response and ADME. For example, cg16919093 on BRCA1 and cg1055436 on FOXL2 were associated with the drug response to breast cancer chemotherapy; cg23283614 on DHRS7 and cg01878807 on DHRS4 were associated Phase I metabolism. We also identified E-CpG sites that triggered gene expression and influenced drug ADME. For example, the interethnic methylation difference for cg27560818 on SLC7A5 partially explained the poorer response to tamoxifen therapy in breast cancer patients with African ancestry than that in breast cancer patients with European ancestry. We also found that a small number of CpG sites exerted both ethnicity and methylation age effects on the drug response. In conclusion, we provide evidence about the influence of interethnic differences in DNA methylation on differential gene regulation and pharmacoepigenetics by tissue types. Ethnicity and tissue types should be carefully accounted for in future clinical practices and pharmacoepigenetics research.
Книги з теми "Pharmacoepigenetic"
Pharmacoepigenetics. Elsevier, 2019. http://dx.doi.org/10.1016/c2017-0-00603-1.
Повний текст джерелаCacabelos, Ramón. Pharmacoepigenetics. Elsevier Science & Technology, 2019.
Знайти повний текст джерелаCacabelos, Ramón. Pharmacoepigenetics. Elsevier Science & Technology Books, 2019.
Знайти повний текст джерелаCacabelos, Ramón. Pharmacoepigenetics. Elsevier Science & Technology Books, 2024.
Знайти повний текст джерелаImani, Saber, Matteo Becatti, and Md Asaduzzaman Khan, eds. Molecular Targeted Therapy in Oncology: Lessons from Pharmacogenetics and Pharmacoepigenetics. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88974-855-6.
Повний текст джерелаЧастини книг з теми "Pharmacoepigenetic"
Zeitoun, R., E. Abou Diwan, R. Nasr, and N. K. Zgheib. "Pharmacoepigenetic Considerations for the Treatment of Breast Cancer." In Pharmacoepigenetics, 531–39. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813939-4.00015-2.
Повний текст джерелаCacabelos, Ramón, Juan C. Carril, Ana Sanmartín, and Pablo Cacabelos. "Pharmacoepigenetic Processors: Epigenetic Drugs, Drug Resistance, Toxicoepigenetics, and Nutriepigenetics." In Pharmacoepigenetics, 191–424. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813939-4.00006-1.
Повний текст джерелаFlanagan, James, and Arturas Petronis. "Pharmacoepigenetics." In Drugs and the Pharmaceutical Sciences, 461–91. CRC Press, 2005. http://dx.doi.org/10.1201/9780849359507.ch20.
Повний текст джерелаCacabelos, Ramón, Iván Tellado, and Pablo Cacabelos. "The Epigenetic Machinery in the Life Cycle and Pharmacoepigenetics." In Pharmacoepigenetics, 1–100. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813939-4.00001-2.
Повний текст джерелаMajchrzak-Celińska, Aleksandra, and Wanda Baer-Dubowska. "Pharmacoepigenetics: Basic Principles for Personalized Medicine." In Pharmacoepigenetics, 101–12. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813939-4.00002-4.
Повний текст джерелаTeijido, Oscar. "Epigenetic Mechanisms in the Regulation of Drug Metabolism and Transport." In Pharmacoepigenetics, 113–28. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813939-4.00003-6.
Повний текст джерелаLi, Dongying, William H. Tolleson, Dianke Yu, Si Chen, Lei Guo, Wenming Xiao, Weida Tong, and Baitang Ning. "MicroRNA-Dependent Gene Regulation of the Human Cytochrome P450." In Pharmacoepigenetics, 129–38. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813939-4.00004-8.
Повний текст джерелаCacabelos, Ramón. "Pathoepigenetics: The Role of Epigenetic Biomarkers in Disease Pathogenesis." In Pharmacoepigenetics, 139–89. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813939-4.00005-x.
Повний текст джерелаDaifuku, Richard. "Pharmacoepigenetics of Novel Nucleoside DNA Methyltransferase Inhibitors." In Pharmacoepigenetics, 425–35. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813939-4.00007-3.
Повний текст джерелаVilwanathan, Ravikumar, Anusha Chidambaram, and Ramesh Kumar Chidambaram. "Pharmacoepigenetics: Novel Mechanistic Insights in Drug Discovery and Development Targeting Chromatin-Modifying Enzymes." In Pharmacoepigenetics, 437–45. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-813939-4.00008-5.
Повний текст джерелаТези доповідей конференцій з теми "Pharmacoepigenetic"
Lopez-Lopez, Elixabet, Idoia Martin-Guerrero, Javier Ballesteros, Javier Uriz, Nagore Garcia de Andoin, M. Angeles Piñan, Pura Garcia-Miguel, Aurora Navajas, and Africa Garcia-Orad. "Abstract B31: Pharmacogenetics and pharmacoepigenetics of childhood acute lymphoblastic leukemia." In Abstracts: AACR International Conference on Translational Cancer Medicine--; Mar 21–24, 2010; Amsterdam, The Netherlands. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1078-0432.tcme10-b31.
Повний текст джерела