Дисертації з теми "Pharmaceutical producers"
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Alev, Isil. "Operational perspectives on extended producer responsibility for durable and consumable products." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/54382.
Повний текст джерелаOliva, Viera Ivette Lorena. "Factores que determinaron el incremento de las importaciones de los productos farmacéuticos chinos en el Perú, entre el 2013 al 2017." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/628116.
Повний текст джерелаThis research aims to determine those factors that generated the increase in imports of Chinese pharmaceutical products in Peru, between 2013 and 2017. In principle, secondary sources of the pharmaceutical industry and application theories were analyzed to better understand the industry and to know the most relevant factors that are driving the increase in these Chinese imports, especially for having a direct impact on health and health. people's well-being According to the exhaustive research in the theoretical framework, it was determined that capital and labor, diversification, logistics costs, policy regime and industrial capacity are determining factors that contribute to the increase in product imports. Chinese pharmacists in Peru. Meanwhile, the applied work methodology corresponds to a qualitative - descriptive study, with a non-experimental design and that uses the in-depth interview as a research instrument, the result of which showed that four of the five factors are considered determinants in relation to Our subject of study. That is, the diversification factor was not considered decisive for the present subject of study. Due to the research, it is recommended that the national and private pharmaceutical industry make better business practices regarding the use of these factors so that they can not only emulate what China has done, but also increase their competitiveness in the Peruvian market towards an industry most strengthened pharmaceutical.
Tesis
Adolfsson, Per. "Export of Pharmaceutical Products : An analysis of which factors that affects Sweden’s export of pharmaceutical products." Thesis, Jönköping University, JIBS, Economics, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-951.
Повний текст джерелаThe pharmaceutical industry is one of Sweden’s most important export industries with 6% of total exports. The purpose of this thesis is to analyse which factors affect Sweden’s ex-port of pharmaceutical products. Further, the different pharmaceutical products group Sweden exports will be identified. The modern trade theory, the monopolistic competition model, the product life cycle theory and the gravity equation are used to explain and to un-derstand the problem at hand.
To analyse the problem, data of Swedish export of pharmaceutical products from 1997 to 2003 was used to the 176 destination countries Sweden exported to during the time period. The following factors were used as independent variables; distance, Gross Domestic Prod-uct (GDP) /capita, Area, Population, dummy variable for EU-membership, dummy vari-able for English or Scandinavian speaking countries, dummy variable for bordering to Sweden, dummy variable for same religion as Sweden and a dummy variable for countries that are not land-locked.
The findings coincide with previous studies in the manner that distance and GDP/capita have a major impact on the sales abroad of pharmaceutical products. Also, countries with a larger population are importing more than countries with a smaller population. However, the strong affinities between the exporter and the importing countries found in previous studies were not found in the export of pharmaceutical products. Further, Sweden exports most of the product group that includes medicaments consisting of mixed or unmixed products for therapeutic or prophylactic uses.
Läkemedelsindustrin är en av Sveriges viktigaste exportindustrier med 6 % av den totala exporten. Syftet med denna uppsats är därför att analysera vilka faktorer som påverkar dess export. Vidare, de olika exportgrupperna av läkemedel som Sverige exporterar kommer att identifieras. Den moderna handelsteorin, monopolistisk konkurrens, produktcykelteorin och gravitationsmodellen används för att förklara och förstå det uppstådda problemet.
För att analysera problemet så används Sveriges export av läkemedel från 1997 till 2003 för alla 176 destinationer. Följande faktorer används som oberoende variabler; distansen, BNP/capita, arean, folkmängd, dummy variabel för EU-medlemskap, dummy variabel för engelsk- eller skandinaviskspråkiga länder, dummy variabel för gränsande länder till Sverige, dummy variabel för länder som har samma religion som Sverige, samt en dummy variabel för länder som angränsar till vatten.
Resultatet överensstämmer med tidigare forskning att avståndet och BNP/capita har ett stort inflytande av exporten av läkemedel. Likaså länder med ett stort invånarantal importe-rar mer än länder med ett mindre invånarantal. Däremot, det starka släktskapet mellan ex-portören och de importerande länderna som funnits i tidigare studier observerades inte i exporten av läkemedel. Vidare, Sverige exporterar mest av produktgruppen som innehåller medikamenter bestående av blandade eller oblandade produkter för terapeutiskt eller profy-laktiskt bruk.
Komak, Wagma, Jeremy Smart, and Jennifer White. "Quality Assessment of Internet Pharmaceutical Products." The University of Arizona, 2007. http://hdl.handle.net/10150/624403.
Повний текст джерелаObjectives: The purpose of this study is to assess the quality of study medications obtained without a prescription through international websites. Methods: Samples of levothyroxine, warfarin, and sildenafil were obtained through various websites and compared to U.S. standards. Each sample was physically evaluated for weight, color, shape, and external tablet markings. High performance liquid chromatography (HPLC) was performed to quantify the amount of active ingredient. Results: When physically inspected, only 3 of the 9 lots met FDA labeling requirements. Three of 60 (20 tablets from 3 lots) of the individual levothyroxine tablets were out of the USP acceptable range (90% - 110%). For warfarin, 16 of the 60 samples (20 samples from 3 lots) of the individual tablets were out of the USP acceptable range (95% - 105%). When averaged, each of the lots for both levothyroxine and warfarin were within their USP acceptable ranges. As sildenafil is not available as generic in the U.S., there is no USP standard acceptable range for comparison. All of the sildenafil samples fell within 90%- 105% of Viagra® tablets obtained from a local pharmacy. Conclusions: While there were a few samples outside of the U.S. acceptable range, the majority of samples analyzed for active ingredient were within the range published in the USP. While the outcomes of this study presented interesting findings, further evaluation in larger studies is needed to properly assess the quality of foreign medications purchased over the internet.
Sadeghnejad, G. R. "Thermoodynamic properties and characterisation of pharmaceutical materials." Thesis, University of Bradford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371530.
Повний текст джерелаÖstlund, Martin. "AssistancePlus : 3D-mediated Advice-giving on Pharmaceutical Products." Licentiate thesis, Linköping University, Linköping University, NLPLAB - Natural Language Processing Laboratory, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-12159.
Повний текст джерелаIn the use of medication and pharmaceutical products, non‐compliance is a major problem. One thing we can do something about is making sure consumers have the information they need. This thesis investigates how remote communication technology can be used to improve the availability for expressive advice‐giving services. Special attention is given to the balancing of expressiveness and availability. A solution is presented that uses 3D visualisation in combination with audio and video communication to convey advice on complex pharmaceutical products. The solution is tested and evaluated in two user studies. The first study is broad and explorative, the second more focused and evaluative. The solution was well received by participating subjects. They welcomed the sense of personal contact that seeing the communicating party over video link produced and appreciated the expressive power and pedagogical value of the 3D materials. Herbert Clark’s theory of use of language is suggested as a framework for the analysis of the dynamics of the relationship between
consumer and advisor.
Report code: LiU-Tek-Lic-2008:31.
Östlund, Martin. "AssistancePlus : 3D-mediated advice-giving on pharmaceutical products /." Linköping : Department of Computer and Information Science, Linköpings universitet, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-12159.
Повний текст джерелаBara, Carlos Roberto Francisco. "Does humor work in advertising of pharmaceutical products?" reponame:Repositório Institucional do FGV, 2010. http://hdl.handle.net/10438/8196.
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This thesis aims to evaluate whether humorous television commercials (TVCs) work for non-prescription drugs, known as “over-the-counter” (OTC). The construct humor in advertising is controversial since it involves complex and broad typology, and depends on the audience characteristics. Several studies within different product categories indicated that some consumer goods are better suited for humorous TVCs, while others, such as OTC drugs, may not take advantage from it. Paradoxically, drug announcers spend billions of dollars worldwide in humorous OTC ads. An experiment with real consumers was designed as between-and-within-subjects, to test three hypotheses. Sixty women were exposed to pairs of humorous and non-humorous TVCs, for each of the three drug categories (analgesics, vitamins, and laxatives). We used fictional brand names and real ads, and measured four dependant variables: attitude toward the advertising (AAD), attitude toward the brand (ABR), purchase intention (PI), and brand choice (BC), after subjects being exposed to manipulations of two independent variables: humorous vs. non-humorous TV commercials, for the drug categories. Conditional logit model confirmed that humor does not help to persuade respondents, whose choices, attitudes, and purchase intention were less favorable with humorous TVCs, in comparison to non-humorous executions. Future research is presented regarding marketing for pharmaceutical products.
Pedrouzo, Lanuza Marta. "Pharmaceuticals and personal care products in environmental waters." Doctoral thesis, Universitat Rovira i Virgili, 2010. http://hdl.handle.net/10803/9058.
Повний текст джерелаIn the framework of the present Doctoral Thesis different analytical methods have been developed to determine pharmaceuticals and personal care products (PPCPs) in environmental waters. The term PPCPs cover all the pharmaceuticals, drugs of abuse, hormones, the active compounds included in personal care products, and also metabolites, conjugates and transformation sub-products. The developed methods were based on solid-phase extraction and stir bar sorptive extraction followed by liquid chromatography coupled to mass spectrometry and tandem mass spectrometry. Achieving the low limits of detection, these methods could be applied to the monitoring of these compounds in different sewage treatment plants from Tarragona Region, where not data were available. The PPCPs resulting in the effluent sewage waters can achieve rivers. Therefore, waters from three rivers: Ter, Llobregat and Ebro were analyzed. To complete the study, also drinking water was analyzed to determine PPCPs.
Gibson, Sara Nichols. "Oxidation of pharmaceuticals and personal products by permanganate." Thesis, Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/33870.
Повний текст джерелаXiao, Ruiyang. "Sonochemical Degradation of Pharmaceuticals and Personal Care Products." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1338345410.
Повний текст джерелаStute, Katrin. "The pharmaceutical manufacturer's duty to warn, a comparative study between German and Canadian pharmaceutical products liability laws." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0006/MQ45156.pdf.
Повний текст джерелаChtourou, Mariem. "Pharmaceutical and personal care products removal by advanced treatment technologies." Doctoral thesis, Universitat de Girona, 2018. http://hdl.handle.net/10803/664966.
Повний текст джерелаAquesta tesi ha avualuat diferents tractament per l'eliminació d'influent amb alta concentració de fàrmacs i productes cosmètics. Primerament, una estat de l’art sobre els diferents tractaments per eliminar triclosan ha permès establir quines tipologies de tractament podrien ser els més rendibles tant a nivell operacional com de costos. Els tractaments avaluats han estat a) adsorció, b) processos d’oxidació avançada, i c) tractament per filtració amb membrana. La tecnologia de membrana va ser una de les tecnologies escollides per analitzar la capacitat per eliminar els productes farmacèutics i cosmètics, així com per poder establir les causes de l’embrutiment de les membranes. Els compostos escollit en aquest estudi van ser el triclosan, la carbamazepina i la cafeïna. Els rendiments d’eliminació van ser elevats pel triclosan i al cafeïna (>90%), mentre que la carbamazepina va ser molt inferior degut a seu poder recalcitrant (<40%). En l’experimentació també es va detectar una inhibició del procés de nitrificació, degut a la presència de triclosan. Aquesta inhibició és va confirmar en un estudi complementari on es va quantificar la pèrdua de la capacitat nitrificant en un 60%. El darrer capítol es centra en l’avaluació de l’adsorció com a tecnologia de tractament. En aquest cas s’ha utilitzat el suro com a material adsorbent i s’han presentat resultats de caracterització del material i resultats de capacitat d’adsorció. Per dur a terme l’experimentació es va triar la tecnologia de llit fix per tractar quatre composts farmacèutics (diclofenac, fetoprofen, naproxen i carbamazepina) i dos productes cosmètics (triclosan i metilparaben). La metodologia d’anàlisi va ser la micro-extracció en tub de silicona amb HPLC-DAD. Els resultats obtinguts van demostrar que el triclosan era el compost amb major capacitat de ser eliminat i el diclofenac el que presentava menors rendiments. TCS> CBZ i MPB> KET i NAP> DCF
Bayliss, M. A. "Studies of cyclic nucleotides and pharmaceutical products by mass spectrometry." Thesis, Swansea University, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.636061.
Повний текст джерелаKundu, Jayeeta. "Cross-country study on the promotion of new pharmaceutical products." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/34524.
Повний текст джерелаIncludes bibliographical references (p. 170-176).
Detailers are one of the most powerful components of pharmaceutical marketing. Drug manufactures spend a lion's share of their marketing budgets on their detailers, and with direct-to-consumer (DTC) marketing coming under closer scrutiny, it is likely that detailing will receive even more funding in the coming years. This thesis analyzes how differences in detailing regulations in the United States, United Kingdom, Sweden, Italy, and France lead to differences in the promotion and sales of antinausea, antihypertensive, and antipsychotic medications during the time period of 1992 to 2003. In order to determine if promotional efforts vary across generations of medications in the same therapeutic class, antinausea and antipsychotic medications are classified as new and old generations and antihypertensives are classified as new, middle, and old generations in this study. Qualitative and quantitative methods are used to examine population, economic, price, promotional, regulatory, and cultural factors that contribute to the sales of pharamaceutical products. The qualitative discussion includes an overview of all five sample countries' health care systems, health care policies, and the prevalence of hypertension, cancer incidence, and psychosis.
(cont.) Econometric tools are used to conduct the quantitative analysis. The effect on pharmaceutical sales and the diffusion of new generation pharmaceutical products is examined. Chow tests are conducted for cross-country differences. This study finds that there are significant cross-country differences in the diffusion of the three therapeutic classes in the five sample countries examined in this thesis. The different factors examined contribute to diffusion in varying extents in the five sample countries. Culture is found to play an important role in the sale and use of all three therapeutic classes, but an especially crucial role in the case of antipsychotics. The promotional factors appear to play a significant role in the diffusion of new generation products relative to older generation products, but are not found to have a statistically significant effect on the larger therapeutic level.
by Jayeeta Kundu.
S.M.
Первун, Юлія Валеріївна. "The beekeeping products in the medical, pharmaceutical and cosmetic practice." Thesis, Київський національний університет технологій та дизайну, 2020. https://er.knutd.edu.ua/handle/123456789/15349.
Повний текст джерелаFazel, Robin. "Enforcing Competition in the Pharmaceutical Sector : - A Multi-Perspective Analysis of Restrictions on Parallel Trade with Pharmaceutical Products." Thesis, Uppsala universitet, Juridiska institutionen, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-379628.
Повний текст джерелаNiesporek, Anna. "Compulsory Licensing of Pharmaceutical Products & Access to Essential Medicines in Developing Countries." Thesis, Linköping University, Department of Management and Economics, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-5488.
Повний текст джерелаFor many years pharmaceutical patents and their impact on prices have been at the centre of the international debate over insufficient access to lifesaving HIV/AIDS medicines in developing countries. The conflict has largely revolved around the implementation of an intellectual property system in the developing world, subsequent the adaptation of the TRIPS Agreement, which has made a 20 year pharmaceutical patent protection mandatory for these countries and consequently contributed to high drug prices for patented medicines as well as limited the use of generic drugs.
Developing countries, where patents are already in place, have sought to reduce high drug prices by making use of compulsory licensing, a safeguarding practice allowing the production or importation of a generic medicine without the consent of the patent holder. Compulsory licences are allowed under the TRIPS Agreement, but disagreements about the conditions, under which compulsory licences are available for ‘essential medicines’, have restricted their use. A definition of the extent to which compulsory licensees can export generic drugs to developing countries unable to manufacture their own has been missing, but on 30 August 2003 the WTO announced that it had resolved this problem by lifting the TRIPS Agreement’s restrictions on exports and permitting exports of drugs produced under a compulsory license as an exception to a patent right. The main question is whether the compulsory licensing system as prescribed in the recent Decision is an ample means of improving access to patented AIDS medicines in the developing world.
By means of legal and economic reasoning this master thesis argues that the 30 August Decision on lifting TRIPS’ restrictions on exports of patented pharmaceuticals produced under compulsory licences provides complex and uncertain rules, rendering an unreliable employment of compulsory licensing. It is desirable that further recommendations are given on which generic producing companies should be awarded compulsory licences and also on which premises. In reality, the debate about compulsory licensing is part of a much wider structural problem in development policy. The solution to the inaccessibility problem requires a mix of courses of action with a functioning compulsory licensing system included. However, disagreements such as how necessary funding should be divided equitably between developed countries could protract the reaching of a pragmatic solution.
Cousineau, Lisa Marie. "Pharmaceutical and personal care product concentrations in the upper Susquehanna River." Diss., Online access via UMI:, 2008.
Знайти повний текст джерелаTsanwani, Mutshutshu. "Application of sequential injection systems in the assay of pharmaceutical products." Diss., Pretoria : [s.n.], 2001. http://upetd.up.ac.za/thesis/available/etd-11212005-165303/.
Повний текст джерелаRamsey, E. D. "Studies of pharmaceutical products and peptides by chromatographic and spectroscopic techniques." Thesis, Cardiff Metropolitan University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.482906.
Повний текст джерелаPatnala, Satya Siva Rama Ranganath Srinivas. "Pharmaceutical analysis and quality of complementary medicines : sceletium and associated products." Thesis, Rhodes University, 2007. http://hdl.handle.net/10962/d1018263.
Повний текст джерелаFerrão, Ângela Filipa Machado. "Clinical research in a pharmaceutical industry." Master's thesis, Universidade de Aveiro, 2015. http://hdl.handle.net/10773/14880.
Повний текст джерелаThis training report describes the knowledge and experience gained during the curricular internship at the Medical Affairs unit of the Research Department of Bluepharma Indústria S.A.. The main activities addressed are related with the conduction of phase I clinical trials by a sponsor, namely bioequivalence clinical trials. In this context, is described the main applicable regulations, the management process of a clinical trial and a reflection about the main challenges in the field. Furthermore, are outlined the activities related with the management of Research, Development and Innovation projects, particularly the analysis of ideas of new pharmaceutical products, where I contribute with several researches. This first contact with the pharmaceutical industry allowed me to integrate the knowledge and skills gained in the Pharmaceutical Sciences degree with those gained in the master’s course of pharmaceutical medicine, fulfilling one of the main objectives that I define for myself: the growth and acquisition of skills, coupled with the access to a different professional reality.
O presente relatório de estágio propõe-se relatar o conhecimento e a experiência adquirida durante o estágio curricular no setor de Assuntos Médicos do departamento de Investigação da Bluepharma Indústria, S.A.. Nele são abordadas as principais atividades realizadas, inerentes à condução de ensaios clínicos de fase I por parte de um promotor, nomeadamente de ensaios de bioequivalência. Neste contexto é feita uma descrição da legislação aplicável, do processo de gestão de um ensaio clínico e uma reflexão acerca dos principais desafios nesta área. Para além disso, são também descritas atividades relacionadas com a gestão de projetos de Investigação, Desenvolvimento e Inovação, particularmente na análise de ideias de novos produtos farmacêuticos para as quais contribuí com diversas pesquisas. Este meu primeiro contacto com a indústria farmacêutica permitiu-me integrar os conhecimentos e competências da licenciatura em Ciências Farmacêuticas com os adquiridos no mestrado de Biomedicina Farmacêutica, cumprindo um dos principais objetivos que estabeleci para mim: o do crescimento e aquisição de competências aliado ao acesso a uma diferente realidade profissional.
Wang, Xiaowen. "Pharmaceuticals and personal care products in the environment in China." Thesis, University of York, 2015. http://etheses.whiterose.ac.uk/13460/.
Повний текст джерелаGoetz, Kristen, and Jennifer Vogel. "A Comparison of Pharmaceutical Products Obtained from the United States and Mexico." The University of Arizona, 2007. http://hdl.handle.net/10150/624398.
Повний текст джерелаObjectives: Despite the growing attention to the issue of patient utilizing foreign pharmaceuticals, the lack of scientific evidence makes it impossible to reach a conclusion about the topic. The objective of this study was to test the content of the active ingredient in three medications (warfarin, levothyroxine, and Viagra/sildenafil), obtained from the United States and Mexico, according to United States Pharmacopeia (USP) standards. Methods: The identification and quantification of the pharmaceutical products was determined utilizing normal and reversed phase high-performance liquid chromatography (HPLC). Each individual tablet was weighed , dissolved in an appropriate solvent, and sonicated to produce a sample for HPLC analysis. Twenty, ten, or six individual samples of each medication were analyzed twice via an appropriate HPLC method, depending on the number of tablets available. In addition, a bulk sample of twenty tablets was analyzed for both warfarin and levothyroxine to assess an average concentration for each sample. Results: The content of levothyroxine in the three Mexico medications was 87.0±2.3%, 104.7±3.1%, and 100.5±14.2%; compared to 98.4±1.4% in the US sample. Warfarin content analysis for the Mexican products resulted in an average of 98.5±2.6%, 95.9±1.1% and 94.8±1.8%; compared to 97.4±2.3% in the US sample. The sildenafil samples from Mexico were found to contain only 67.8±3.8% and 71.1±1.0% of what the US sample contained. Conclusions: Six out of the eight samples collected from Mexican pharmacies contained lower amounts of active ingredient than their US equivalents. In terms of the average concentration, many of the medications from Mexico fell within the USP range but there was great variation in the content of each individual tablet.
Are, Celeste. "Una estrategia unificada para la síntesis enantioselectiva de los alcaloides del grupo de las madangaminas." Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/663395.
Повний текст джерелаMadangamines alkaloids constitute a small group of complex pentacyclic alkaloids isolated from marine sponges of the order Haposclerida. Structurally, these alkaloids have an unprecedented skeletal type, characterized by a diazatricyclic core (ABC rings) and two linear carbon bridges. The peripheral macrocyclic ring D is different in each madangamine, in size as well as in degree and position of unsaturation, whereas ring E is identical in madangamines A-E. In the context of our studies on the enantioselective synthesis of complex piperidine-containing natural products from phenylglycinol- derived bicyclic lactams, we have developed a unified strategy to access the variety of alkaloids of this group. Appling this strategy, that involves the formation of the macrocyclic rings after the construction of the highly functionalized central core, recently in our group was carried out the enantioselective synthesis of madangamine D, which represents the first total synthesis of an alkaloid of the madangamine group.1 In this Doctoral Thesis we focused our attention in the total synthesis of other members of the family: madangamines A, B, C and E. Starting from tricyclic intermediate 16, which was prepared by 13 steps, we performed the construction of the complex E ring, common to madangamines A-E. The construction of the different D rings was explored in model compounds as well in the tricyclic and tetracyclic intermediates; these studies allowed to accomplish the synthesis of the ring of madangamine B in a piperidine derivative, the ABCD system of madangamines C and E and the pentacyclic system of madangamine A, which represent the formal synthesis of this alkaloid.
Fichana, Daniel. "Green engineering and gate-to gate life cycle assessments for pharmaceutical products /." Full text available online, 2005. http://www.lib.rowan.edu/find/theses.
Повний текст джерелаFidora, Aldo F. "Knowledge and Barriers to Safe Disposal of Pharmaceutical Products Entering the Environment." Thesis, Walden University, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10689631.
Повний текст джерелаThe use of pharmaceutical products has steadily increased in the United States from 2 billion prescriptions in 1999 to 3.9 billion in 2009. Half of patients do not comply with the recommended prescription regimen and dispose of unused drugs in the environment. The U.S. Environmental Protection Agency and many researchers have highlighted the human-health risks associated with improperly disposing of pharmaceutical products. This quantitative cross-sectional study examined the potential correlations between people’s actual disposal practices and their knowledge of the impact of disposal practices on the environment and human health, and availability of disposal options. The conceptual framework selected for this study comprised 2 models: the health belief model and the theory of planned behavior. Respondents to an online survey were 485 residents of the northeast United States, polled from the general population. Descriptive statistics and logistic regression were used to model responses from the dependent variable actual disposal practice (ADP) across the independent variables, and analysis of variance explored whether ADP differed across demographic variables. Statistically significant associations emerged among individuals’ knowledge of environment and human-health impact, recommended disposal practices, disposal options, and that person’s likelihood to practice recommended disposal. Demographic variables did not impact disposal behavior. To promote positive social change, it is recommended that policymakers plan and implement the expansion of convenient drug disposal options, as well as information campaigns on proper disposal practices. In parallel, health care professionals should stress to their patients the importance of complying with prescribed regimens, thus minimizing the amount of unused or expired medications.
Cheasty, A. G. "Investigation of combined separation-mass spectrometry for the analysis of pharmaceutical products." Thesis, Swansea University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.636237.
Повний текст джерелаKrishnamurthy, Prashanth M. Eng Massachusetts Institute of Technology, and Amit Prasad. "Inventory strategies for patented and generic products for a pharmaceutical supply chain." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/77540.
Повний текст джерелаCataloged from PDF version of thesis.
Includes bibliographical references (p. 76-77).
This thesis presents a model to determine safety stock considering the distinct planning parameters for a pharmaceutical company. Traditional parameters such as forecast accuracy, service level requirements and average lead-time are combined with a nontraditional upstream uncertainty parameter defined as supply reliability. In this instance, supply reliability measures uncertainty in the supply quantity delivered rather than variability in the lead-time for delivery. We consider the impact of the safety stock using two products: a proprietary product that is patented and a generic product that recently went off patent. Sensitivity analysis is performed to provide insights on the impact of variations in input parameters. The study shows that there is a significant difference in safety stock between the proposed model and the current model used by the company.
by Prashanth Krishnamurthy and Amit Prasad.
M.Eng.in Logistics
Conislla-Murquia, Teresa, Anait Saico-Sulla, Claudia León-Chavarri, Jose Maria Alvarez, and Carlos Raymundo-Ibañez. "Lean healthcare model for increasing the availability of products in pharmaceutical SMEs." Association for Computing Machinery, 2019. http://hdl.handle.net/10757/656252.
Повний текст джерелаNowadays, retailers in the trade industry are focused on meeting customers’ needs, as their priority is to make as many sales per day as possible. Stockouts lead to unattended sales, which mean loss of income. This endangers the place of the MSBs in the industry. This paper aims to prove that proposing a supply management model will reduce the number of lost sales due to stockouts. For this study, we analyzed three key processes (purchasing, storage and distribution), where we identified problems such as incomplete shipments and unfulfilled POs and replacement requests. To prove the viability of our proposal, a pilot was carried out in a pharmacy that has five dispensing premises and a central warehouse, which improved its stock availability from 82% to 89.5%.
Bell, Charlotte. "Advanced analytical and microbial methods for biopharmaceutical and pharmaceutical products and processes." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/2736.
Повний текст джерелаFidora, Aldo Francesco. "Knowledge and Barriers to Safe Disposal of Pharmaceutical Products Entering the Environment." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4624.
Повний текст джерелаVesper, James. "Developing expertise of those handling temperature-sensitive pharmaceutical products using e-learning." Thesis, Vesper, James (2014) Developing expertise of those handling temperature-sensitive pharmaceutical products using e-learning. PhD thesis, Murdoch University, 2014. https://researchrepository.murdoch.edu.au/id/eprint/24443/.
Повний текст джерелаJaén, Gil Adrián. "Removal of pharmaceuticals in wastewater combining different treatment technologies: suspect screening identification and risk assessment of transformation products." Doctoral thesis, Universitat de Girona, 2021. http://hdl.handle.net/10803/673419.
Повний текст джерелаLa baja eficiencia de las plantas de tratamiento de aguas residuales para lograr la completa eliminación de microcontaminantes, incluidos los fármacos, ha motivado el desarrollo de tecnologías alternativas para mejorar su eficiencia, sostenibilidad y costos operativos. Sin embargo, incluso cuando la eliminación completa de estos contaminantes es alcanzada, éstos pueden transformarse en intermedios nuevos y desconocidos que podrían ser más persistentes y tóxicos que sus compuestos originales. En esta tesis doctoral, se han desarrollado metodologías analíticas avanzadas para la identificación de los productos de transformación generados a lo largo de tratamientos biológicos y físicos y/o químicos. Además, se han evaluado sus posibles efectos ambientales mediante métodos in silico y bioensayos in vitro en efluentes tratados. Por último, se ha investigado su eficiencia de eliminación en tecnologías de agua combinadas. Esta tesis doctoral demuestra que la investigación multidisciplinaria es necesaria para evaluar la mejor tecnología de tratamiento de agua a utilizar
Programa de Doctorat en Ciència i Tecnologia de l'Aigua
Anderson, Margaret Marie. "Cytotoxic and antimalarial natural products." Thesis, University College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320404.
Повний текст джерелаWild, Tracy Joy. "Pharmaceutical analysis and aspects of the quality control of St. John's Wort products." Thesis, Rhodes University, 2003. http://hdl.handle.net/10962/d1003282.
Повний текст джерелаMarques, Pereira M. L. "Analysis of pharmaceutical products and nucleotides by LC-MS and tandem mass spectrometry." Thesis, Swansea University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.638005.
Повний текст джерелаShakoor, Omar. "Some aspects of the quality of certain pharmaceutical products from Nigeria and Thailand." Thesis, Robert Gordon University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243784.
Повний текст джерелаKok, Yixiong. "The production planning and inventory management of intermediate products for a pharmaceutical company." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/42319.
Повний текст джерелаIncludes bibliographical references (p. 66).
TCG is a multinational pharmaceutical company. As part of its drive to stay lean and competitive, TCG hopes to effectively maximize its capital assets by reducing warehouse inventory. This thesis aims to reduce the inventory of intermediate products through the use of fixed demand rate production planning and inventory controls. The production planning model attempts to derive the optimal production cycle time based on demand rates, production rates and setup times to prevent stock outs. The optimal cycle time should provide the optimal inventory levels for the intermediate products. The production planning model stabilizes the fluctuations in inventory levels and outperforms TCG's production plan in 2008 by 115 pallet spaces. With an order-up-to policy, the inventory level is capped at a maximum level, preventing uncontrolled accumulation of inventory of the intermediate products. This will prevent stock outs and stabilize inventory levels. Using an order-up-to policy to minimize the inventory, a reduction of up to 1.8% can be achieved.
by Yixiong Kok.
M.Eng.
Brown, Stacy D., Loren M. Kirk, and Paul Lewis. "Using Metabolomic Tools to Study Impurity Profiles in Vancomycin Products." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/5280.
Повний текст джерелаPleasance, S. "Studies of pharmaceuticals and food products by combined chromatographic/mass spectrometric techniques." Thesis, Bucks New University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384630.
Повний текст джерелаHe, Kai. "Removal mechanisms of pharmaceuticals and personal care products during soil aquifer treatment." 京都大学 (Kyoto University), 2016. http://hdl.handle.net/2433/217162.
Повний текст джерелаKarlsson, Maja V. "Uptake of pharmaceuticals and personal care products from sediments into aquatic organisms." Thesis, University of York, 2013. http://etheses.whiterose.ac.uk/4173/.
Повний текст джерелаLafferty, Susan Vera. "Evaluation of the properties of polymers used as controlled release membranes." Thesis, University College London (University of London), 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391523.
Повний текст джерелаSun, Dong. "Virtualization and real-time analysis of pharmaceutical and food products by near infrared spectroscopy." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/459155.
Повний текст джерелаThe realization of the smart factory has been investigated in this Thesis. The smart factory is a trend of development in the information age. Human beings could receive a lot of assistance from the smart tools which make works be done in a high quality way. Technology-intensive industries, such as pharmaceutical and modern food industries, are pioneers who have the advantages to enjoy the smart factory. Nowadays, the product quality is a key factor that determines the market share. In order to assure a high quality both in the process and final product, several institutions have published some guidelines. Quality by Design (QbD) and Process analytical technology (PAT) were two guidelines used in this thesis for the pharmaceutical methods. Near infrared spectroscopy (NIRS) could virtualize the physical and chemical information of the process product in real time. Therefore, it was taken as the smart tool to realize these concepts in the pharmaceutical industry and study about the food quality improvement. A portable MicroNIR spectrometer was used to determine critical quality attributes in different stages of the pharmaceutical process for the manufacturing of solid formulations. Quantitative partial least-squares regression models were calculated and validated. The MicroNIR has a miniaturized size, low energy consumption and rugged optical system. So it has shown a good robustness in the operation process. The experiment design has offered a simple way to calculate the models without a complex reference method. The good results of validation reveal that the MicroNIR is an excellent PAT tool in the pharmaceutical industry. The MicroNIR was also adopted to calculate and validate a spectral library to identify 223 pharmaceutical formulations. The internal and external validations have shown that all the formulations can be uniquely identified. This simple and nondestructive method has offered the customer a simple tool to qualify the pharmaceutical product in the retail stores. Besides, the benchtop NIR spectrometer was also adopted to analyze several chemical and sensory parameters of tomato. The analysis was operated in real time mode without any sample pretreatment. The quantitative models were calculated by PLS. The predictive ability was good and it was demonstrated that NIRS is a robust, accurate and safe method to improve the quality of tomato product. Based on the discussion above, this Thesis has studied the application of NIRS as a tool to virtualize and real time analyze pharmaceutical and food industries. All these studies have indicated that the NIRS is a suitable technology for the realization of the smart factory.
Maijó, Ferré Irene. "Preconcentration strategies in capillary electrophoresis for the determination of pharmaceutical and personal care products." Doctoral thesis, Universitat Rovira i Virgili, 2012. http://hdl.handle.net/10803/84043.
Повний текст джерелаThe main objective of this Doctoral Thesis is the development of different strategies to decrease the detection limits of capillary electrophoresis for the determination of pharmaceutical and personal care products. These strategies are based on electrophoretic and chromatographic preconcentration techniques, and the use of mass spectrometry as a detection system. The electrophoretic preconcentration techniques studied included sample stacking techniques and sweeping while the chromatographic preconcentration technique evaluated was in-line coupling between solid phase extraction and capillary electrophoresis. With respect to PPCPs, this Doctoral Thesis focuses specifically on non-steroidal anti-inflammatory drugs (NSAIDs), parabens and UV-filters. Another objective of this Doctoral Thesis is to study the suitability of the developed methodologies for the determination of PPCPs in environmental samples.
Morton, Mark Richard. "Detection and qualification of drugs and impurities in pharmaceutical products by near infrared spectroscopy." Thesis, University College London (University of London), 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501526.
Повний текст джерелаMattern, Kai [Verfasser], Iordana Akademischer Betreuer] Constantinou, and Christel [Akademischer Betreuer] [Müller-Goymann. "Microfluidic devices for screening of pharmaceutical products / Kai Mattern ; Iordana Constantinou, Christel Müller-Goymann." Braunschweig : Technische Universität Braunschweig, 2020. http://d-nb.info/1220027200/34.
Повний текст джерелаMattern, Kai Verfasser], Iordana [Akademischer Betreuer] Constantinou, and Christel [Akademischer Betreuer] [Müller-Goymann. "Microfluidic devices for screening of pharmaceutical products / Kai Mattern ; Iordana Constantinou, Christel Müller-Goymann." Braunschweig : Technische Universität Braunschweig, 2020. http://d-nb.info/1220027200/34.
Повний текст джерела