Добірка наукової літератури з теми "Percutaneous implants"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся зі списками актуальних статей, книг, дисертацій, тез та інших наукових джерел на тему "Percutaneous implants".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Статті в журналах з теми "Percutaneous implants"
1
Wade, Phillip S., Jerry J. Halik, and Marshall Chasin. "Bone Conduction Implants: Transcutaneous vs. Percutaneous." Otolaryngology–Head and Neck Surgery 106, no. 1 (January 1992): 68–74. http://dx.doi.org/10.1177/019459989210600130.
Повний текст джерелаАнотація:
Clinical experience with transcutaneous bone conduction implants has demonstrated that they are most beneficial for patients with purely conductive hearing loss in at least one ear. Percutaneous bone conduction implants, however, have been reported to provide adequate benefit for patients with mixed hearing loss with bone conduction pure-tone averages up to 45 db hl (Tjellstrom, 1989). The results of 24 Xomed Audiant osseointegrated bone conduction hearing devices (including a clinical trial on two patients using a new, larger magnet [Neodynium Iron Boron]), plus the results of eleven patients implanted and fitted with the percutaneous bone-anchored hearing aid are reported. Aided results with these devices will be presented. In addition, general comparisons of benefit obtained with the two devices will be made for patients who exhibit similar hearing losses. Finally, a direct comparison will be made on two patients who have undergone both implant procedures.
2
Theil, Jacob H., Jennifer L. Johns, Poyin Chen, David M. Theil, and Megan A. Albertelli. "Hematology and Culture Assessment of Cranially Implanted Rhesus Macaques (Macaca mulatta)." Comparative Medicine 71, no. 2 (April 1, 2021): 166–76. http://dx.doi.org/10.30802/aalas-cm-20-000084.
Повний текст джерелаАнотація:
The use of percutaneous cranial implants in rhesus macaques (Macaca mulatta) has long been a valuable tool for neuroscience research. However, when treating and assessing these animals, veterinarians are required to make assumptions about diagnostic results due to a lack of research into how these implants affect physiology. Microbial cultures of cranial implant sites show an abundance of colonizing bacteria, but whether these microbes affect animal health and wellbeing is poorly understood. In addition, microbial antibiotic resistance can present significant health concerns for both the animals and the researchers. To help elucidate the relationship between percutaneous cranial implants and blood parameters, complete blood cell counts and serum chemistry results were assessed on 57 nonhuman primates at our institution from September 2001 to March 2017. Generalized estimating equations were used to compare the results before and after an animal's first implant surgery. This modelling showed that cranial implants were a significant predictor of alterations in the number of neutrophils, lymphocytes, and red blood cells, and in the concentration of hemoglobin, alkaline phosphatase, creatinine, calcium, phos- phorus, total protein, albumin, and globulin. Anaerobic and aerobic bacterial cultures were performed to identify bacteria associated with cranial implants. Staphylococcus spp., Streptococcus spp., and Corynebacterium spp. comprised the majority of the aerobic bacterial isolates, while Fusobacterium spp., Peptostreptococcus spp. and Bacterioides fragilis comprised the majority of anaerobic bacterial isolates. Using a Pearson r correlation for statistical analysis, we assessed whether any of these bacterial isolates developed antibiotic resistances over time. Cefazolin, the most frequently used antibiotic in monkeys in this study, was the only antimicrobial out of 41 agents tested to which bacteria developed resistance over time. These results indicate that percutaneous implants are associated with a generalized inflammatory state, multiple bacterial species are present at the implant site, and these bacteria may contribute to the inflammatory response.
3
Parkin, James L., and Matthew J. Parkin. "Multichannel Cochlear Implantation with Percutaneous Pedestal." Ear, Nose & Throat Journal 73, no. 3 (March 1994): 156–64. http://dx.doi.org/10.1177/014556139407300308.
Повний текст джерелаАнотація:
In a prospective study by Cohen et al,3 the superiority of multi channel cochlear implant patient performance over single-channel cochlear implant performance was demonstrated. The Ineraid system described in this paper includes a percutaneous pedestal which has had a satisfactory patient experience. Only one pedestal removal has been necessary because of specific pedestal problems. Other less serious pedestal problems decrease in frequency with increasing time post-implantation. The auditory performance indicates significant commu nication skills improvement in patients with multichannel cochlear implants.
4
Mylanus, E. A. M., and C. W. R. J. Cremers. "A one-stage surgical procedure for placement of percutaneous implants for the bone-anchored hearing aid." Journal of Laryngology & Otology 108, no. 12 (December 1994): 1031–35. http://dx.doi.org/10.1017/s002221510012883x.
Повний текст джерелаАнотація:
AbstractThe bone-anchored hearing aid (BAHA) is an alternative to the conventional bone conduction hearing aid. The transducer is coupled to a percutaneous titanium implant which is traditionally inserted into the temporal bone in two stages. This study focusses on a one-stage surgical technique for the implantation of percutaneous implants. The preliminary clinical results of 33 one-stage implants in 33 patients are presented.Post-operative necrosis of the skin grafts did not occur. After a follow-up which varied from nine to 25 months, 31 out of the 33 fixtures (94 per cent) were anchored firmly in the skull. Twenty-six out of the 33 implants (79 per cent) remained free from potentially dangerous skin reactions. The results were statistically comparable to those obtained with two-stage implants at the same clinic. Although longer follow-up is needed before a general statement can be made about replacing the two-stage technique, the preliminary one-stage results are promising.
5
Heimke, G�nther. "Biomaterials highlights VIII. Percutaneous implants." Advanced Materials 3, no. 2 (February 1991): 108–10. http://dx.doi.org/10.1002/adma.19910030210.
Повний текст джерела
6
Winnen, Rolf G., Kristian Kniha, Ali Modabber, Faruk Al-Sibai, Andreas Braun, Reinhold Kneer, and Frank Hölzle. "Reversal of Osseointegration as a Novel Perspective for the Removal of Failed Dental Implants: A Review of Five Patented Methods." Materials 14, no. 24 (December 17, 2021): 7829. http://dx.doi.org/10.3390/ma14247829.
Повний текст джерелаАнотація:
Osseointegration is the basis of successful dental implantology and the foundation of cementless arthroplasty and the osseointegrated percutaneous prosthetic system. Osseointegration has been considered irreversible thus far. However, controlled heating or cooling of dental implants could selectively damage the bone at the bone–implant interface, causing the reversal of osseointegration or “osseodisintegration”. This review compares five methods for implant removal, published as patent documents between 2010 and 2018, which have not yet been discussed in the scientific literature. We describe these methods and evaluate their potential for reversing osseointegration. The five methods have several technical and methodological similarities: all methods include a handpiece, a connecting device for coronal access, and a controlling device, as well as the application of mechanical and/or thermal energy. The proposed method of quantifying the temperature with a sensor as the sole means for regulating the process seems inadequate. A database used in one of the methods, however, allows a more precise correlation between a selected implant and the energy needed for its removal, thus avoiding unnecessary trauma to the patient. A flapless, microinvasive, and bone-conserving approach for removing failed dental implants, facilitating successful reimplantation, would benefit dental implantology. These methods could be adapted to cementless medical implants and osseointegrated percutaneous prosthetics. However, for some of the methods discussed herein, further research may be necessary.
7
Basciani MD, Reto M., and Balthasar Eberle. "Percutaneous aortic valve implants under sedation." Catheterization and Cardiovascular Interventions 74, no. 1 (July 1, 2009): 148–49. http://dx.doi.org/10.1002/ccd.22026.
Повний текст джерела
8
Di Dona, Francesco, Giovanni Della Valle, Barbara Lamagna, Caterina Balestriere, Carla Murino, Bruna Santangelo, Francesco Lamagna, and Gerardo Fatone. "Percutaneous transilial pinning for treatment of seventh lumbar vertebral body fracture." Veterinary and Comparative Orthopaedics and Traumatology 29, no. 02 (March 2016): 164–69. http://dx.doi.org/10.3415/vcot-15-01-0003.
Повний текст джерелаАнотація:
SummaryObjective: To evaluate outcomes after percutaneous application of transilial pinning in dogs with seventh lumbar vertebral body fracture with concurrent lumbosacral luxation.Methods: We reviewed the medical records of dogs with seventh lumbar vertebral body fracture stabilized with percutaneous transilial pinning that were treated at our hospital between January 2000 and March 2014. Radiographic measurements were used for comparing craniocaudal and ventrodorsal displacement pre- and postoperatively.Results: Seventeen dogs met the inclusion criteria. The neurological status of the majority of treated dogs improved quickly, with immediate pain reduction after surgery. Implants were well tolerated throughout the application period and were removed at a mean time of 54.4 ± 9.2 days. One dog experienced a major complication (implant failure) and required surgical revision a week after the initial procedure. Minor complications included pin-tract inflammation, signs of back pain lasting five weeks and acute lameness after implant removal. Postoperative radiographic measurements showed shortening of the vertebral body and residual dorsoventral dislocation. Otherwise, functional recovery was good (5 of 17 dogs) to excellent (10 of 17 dogs) in the majority of the patients.Clinical relevance: The use of two percutaneous transilial pins can be considered as treatment for the management of seventh lumbar fracture-luxation in dogs. Our modified stabilization technique is relatively easy to perform; less invasive on the soft tissues; and uses implants that are versatile, modifiable, and easily removable.
9
Galambos, David Maxwell, Aliaksei Salei, Soroush Rais-Bahrami, and Rakesh K. Varma. "Intrahepatic renal cell carcinoma implantation along a percutaneous biopsy and cryoablation probe tract." BMJ Case Reports 15, no. 5 (May 2022): e248250. http://dx.doi.org/10.1136/bcr-2021-248250.
Повний текст джерелаАнотація:
A man in his 60s underwent percutaneous biopsy and cryoablation of a right upper pole clear cell renal cell carcinoma followed by repeat cryoablation 8 months later for possible residual disease. The patient was followed with imaging with documented stability for 19 months after repeat ablation. However, imaging at 32 months demonstrated intrahepatic nodular enhancing lesions along the initial percutaneous biopsy and ablation tract, consistent with metastatic implantation. The patient underwent repeat percutaneous biopsy and two rounds of microwave ablation for treatment of the intrahepatic implants, with no residual disease at 10 months postablation. While needle tract seeding is a known complication of percutaneous manipulation of various abdominopelvic malignancies, there have been no prior reports of intrahepatic metastatic implants related to percutaneous renal cell carcinoma ablation. Awareness of this potential complication is important for treatment planning, informed consent and surveillance. This report shares our experience of the management of intrahepatic metastatic implants.
10
Kim, Jong T., Leonard M. Rudolf, and John A. Glaser. "Outcome of Percutaneous Sacroiliac Joint Fixation with Porous Plasma-Coated Triangular Titanium Implants: An Independent Review." Open Orthopaedics Journal 7, no. 1 (February 22, 2013): 51–56. http://dx.doi.org/10.2174/1874325001307010051.
Повний текст джерелаАнотація:
Design: Independent retrospective review of a single surgeon’s experience with a new technique of SI fixation. Objective: Examine results of percutaneous fixation of the SI joint with porous coated triangular titanium implants. Background: Diagnosis and treatment of a dysfunctional sacroiliac joint is challenging as well as controversial. Recently, percutaneous stabilization techniques have been implemented for fixation. There is minimal literature published on this technique. Methods: Charts, radiographs, and CT scans of 31 patients operated on by a single surgeon were de-identified and randomized and then reviewed by investigators not involved with the care of the patients. Reviewers had no relationship with the implant manufacturer at the time of the review. Outcome Measures: intraoperative and postoperative complication, EBL, hospital stays, postoperative image location and number of lucent implants, ingrowth into implants, and bone across SI joint. Results: 27 patients expressed satisfaction, 4 patients did not. Pain relief was noted to be Complete (16 patients), Excellent (5 patients), Good (9 patients), and Fair (1 patients). Four patients had postoperative complications. These were infected hematoma (2), L5 nerve root irritation (1), and L5-S1 discitis (1). One patient required revision. On 6 month postop CT scan, 18/19 patients had radiographic evidence of bone ingrowth and bone into or across the SI joint was evident in 8/19 patients. Lucency was noted around at least one implant in 5/19 patients. Conclusions: Results are promising for the use of this novel implant for a carefully selected group of patients with disabling SI dysfunction.
Дисертації з теми "Percutaneous implants"
1
Chehroudi, Babak. "The effects of surface topography on the behaviour of cells attached to percutaneous implants." Thesis, University of British Columbia, 1991. http://hdl.handle.net/2429/30984.
Повний текст джерелаАнотація:
Epithelial downgrowth on implants can result in deep pockets or sinus tracts which in turn can lead to marsupialization and eventual failure of the implant. One solution to this problem would be to have a surface of an implant that has the ability to impede the apical migration of epithelium. The present studies were aimed to determine whether surface topography could be used to impede epithelial downgrowth on percutaneous implants based on those principles that have been found to control the direction and rate of cell migration in vitro. Studies in culture have indicated that cells can be guided by the grooved surfaces, a phenomenon called contact guidance.
In the first series of experiments, the effects of a V-shaped, 10-μim-deep grooved epoxy or titanium-coated epoxy substrata were studied on epithelial (E) cell behaviour. In vitro, grooved surfaces encouraged E cell adhesion and oriented clusters of E cells along their long axis. Seven or 10 days after percutaneous implantation of grooved and control smooth surfaces in rats, grooved surfaces significantly inhibited epithelial downgrowth on the epoxy or titanium-coated epoxy implants.
In the second series of experiments, the effects of groove parameters such as depth, spacing and orientation were tested in vivo. Grooves were produced with a 39, 30 and 7 μm pitch and depths of 19, 10 or 3 μm. After 7 days percutaneous implantation of titanium-coated implants epithelial downgrowth was accelerated on the vertically oriented, 3 or 10 μm-deep, grooved surfaces and inhibited on the horizontally oriented grooved surfaces; an observation that could represent the most direct evidence of contact guidance occurring in vivo. In the shallower horizontal grooves [≤10 μm-deep] epithelial downgrowth was probably inhibited by contact guidance because there was no evidence of fibroblasts (F) inserting into the implant surface. However, in the 19 μm-deep grooved surfaces, E cells bridged over the grooves and their migration appeared to be inhibited by the F that inserted into the implant surface.
In the third series of experiments, the ultrastructural observations indicated that E cells closely attached to the smooth, and interdigitated with, the 3 μm and 10 μm grooved surfaces of titanium-coated implants. This attachment appeared to be through basal lamina and hemidesmosome-like
structures. The ultrastructural observations on the orientation of E cells and F attached to the implant verified those noted at the light microscopic level. The attachment of F to the titanium surface was mediated by two zones; a thin [≈20 nm], amorphous, electron dense zone immediately contacting the titanium surface, and a fine fibrillar zone extending from the amorphous zone to the cell membrane.
The objectives of the fourth experiment were [1] to examine cell behaviour on implants in which connective tissue contacted surfaces of various topographies and epithelium encountered only a smooth surface; [2] to compare one-stage and two-stage surgical techniques. Implants delivered micromachined surfaces to the connective tissue and a smooth control surface to the epithelium and implants were removed l,2,and 3 weeks following percutaneous implantation. A complex connective tissue organization that changed with time was noted on the micromachined surfaces whereas a capsule formed on the smooth surfaces. In some cases foci of mineralization were observed on the micromachined surfaces placed using a two-stage surgical technique. Apical migration of the epithelium was significantly (p<.05) inhibited on all surfaces placed by the two-stage technique and by those micromachined surfaces that produced connective tissue ingrowth.
In the fifth study, the ultrastructural observations of the mineralized tissue formed on the micromachined surfaces, identified osteocyte-like cells and in some areas revealed close juxtapositioning of collagen and minerals to titanium without an intervening amorphous layer.
The findings collectively indicate that contact guidance occurs on artificial surfaces in vivo, and micromachined surfaces could be incorporated advantageously to the design of implant surfaces to optimize their performance.Science, Faculty of
Botany, Department of
Zoology, Department of
Graduate
2
Ting, Cara M. "Designing Biomaterial Surfaces to Enhance Adhesion at the Skin-Implant Interface." Digital WPI, 2011. https://digitalcommons.wpi.edu/etd-theses/686.
Повний текст джерелаАнотація:
The skin-implant interface of percutaneous devices is generally weak and can fail when excessive loading disrupts the sealing of the interface by dermal and epidermal cells and tissue. As such, the formation of a stable implant-skin junction is a major factor in determining percutaneous implant success. In this study, we used functionalized self-assembled monolayers (SAMs) with discrete surface properties as model systems to assess the effects of biomaterial surface properties on controlling fibronectin (FN) adsorption and keratinocyte spreading and adhesion. The surface properties investigated were charge (positive and negative) and wettability (hydrophobic and hydrophilic). Gold slides prepared with SAMs were incubated with FN overnight. The cell binding sites were quantified on each surface using an antibody that targets the synergy binding site of the cell binding domains (HFN7.1) and the topography of the FN on the surfaces was evaluated with atomic force microscopy. The topography data demonstrated that the availability of cell binding domains is dependent on surface-mediated FN binding orientation. Cell spreading was assessed using a lipid membrane stain, maleimide. The cells were imaged by fluorescence microscopy and the cell area calculated. The percentage of cell adhesion was determined using a centrifugal force assay. Both keratinocyte assays suggested that the charge of the surface was the prominent factor in determining cell function on the surface over the surface wettability. The findings of this study strongly suggest that a positively charged implant surface with a FN coating will enhance the strength of the cutaneous seal around percutaneous implants over an unmodified surface.
3
Pansard, Rafael Boeira. "IMPLANTE DE CATETER DE DIÁLISE PERITONEAL: TÉCNICA DE SELDINGER E TÉCNICA CIRÚRGICA, RESULTADOS NO HOSPITAL UNIVERSITÁRIO DE SANTA MARIA." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/5848.
Повний текст джерелаАнотація:
Peritoneal dialysis (PD) is a well-established modality of renal replacement
therapy, which has as a principle for its proper function the guaranteed access to the
peritoneal cavity. PD catheter implant technique should be safe, as well as provide
minimal inconvenience to the patient, agility for the service, and few complications. At
the University Hospital of Santa Maria (HUSM; Santa Maria, RS, Brazil), the
catheters were inserted by laparotomy since the 1980s. It is been desired by the
Nephrology department an alternative to facilitate the procedure, leading to greater
agility and greater autonomy of the service. This study aimed to analyze the results
obtained by professionals trained to implant peritoneal catheters with the Seldinger
technique, recently implemented, and those obtained with the standard surgical
technique. The samples were obtained from medical records of patients with endstage
chronic kidney disease at the Nephrology department of HUSM with peritoneal
dialysis indication (n=104). The demographic profile of the patients was evaluated, as
well as the presence of infection and / or bleeding in the surgical wound, the first
infusion and the 30-day functionality of the catheters, and the survival rate one and
two years after implant. Data for each peritoneal catheter insertion mode were
expressed as frequencies and then compared by chi-square, Fisher exact or Mann
Whitey tests, with a 5% significance level. The profile of the two groups had similar
characteristics in relation to gender, age, history of diabetes mellitus and arterial
hypertension. The functionality of the implant at first infusion was also similar for both
groups (83.9%for Seldinger vs. 79% for surgery). When evaluated the functionality in
30 days, the Seldinger technique demonstrated a higher success rate (76.7%) than
the surgical technique (43.6%) (P-value=0,002). Regarding the presence of infection
and / or bleeding in the outside wound, the percentage was similar for both groups
(14.8% for Seldinger vs. 16.9% for surgical). The survival rate of the catheters at 1
and 2 years was also similar for both groups (37% and 14.8% for Seldinger, 23.7%
and 20.6% for surgery, respectively). Given these results, it can be concluded that
the implant of peritoneal catheters by Seldinger technique is a qualified alternative
that allows greater agility to the service since it is an ambulatory procedure, can be
performed by nephrologists and involves less patient management; having similar
functionality to surgical implant according to the experience reported at HUSM.A diálise peritoneal (DP) é uma modalidade bem estabelecida de terapia renal substitutiva, que tem como princípio para seu bom funcionamento a garantia de acesso à cavidade peritoneal. A técnica de implante do cateter de DP deve ser segura, além de proporcionar o mínimo de inconveniência para o paciente, agilidade para o serviço, e poucas complicações. No Hospital Universitário de Santa Maria (HUSM; Santa Maria, RS, Brasil) os cateteres foram implantados por laparotomia desde a década de 1980. É almejada pelo Serviço de Nefrologia uma alternativa que facilite o procedimento, levando a maior agilidade e autonomia do Serviço. O presente trabalho se propôs a analisar os resultados obtidos, por profissionais treinados para implante de cateter peritoneal com a técnica percutânea de Seldinger, recentemente implantada, e os resultados obtidos com a técnica padrão, a cirúrgica. As amostras foram obtidas de dados dos prontuários de pacientes entre os pacientes com insuficiência renal crônica terminal do Serviço de Nefrologia do HUSM com indicação de diálise peritoneal (n=104). Foi avaliado o perfil demográfico dos pacientes, assim como a presença de infecção e/ou sangramento na ferida operatória, a funcionalidade do cateter na primeira infusão e após30dias, além da taxa de sobrevivência em um e dois anos após o implante. Os dados obtidos em cada modalidade de implante de cateter peritoneal foram expressos em frequências e posteriormente comparados pelos testes Qui-Quadrado, Exato de Fischer ou Mann Whitey, com um nível de significância de 5%. O perfil dos dois grupos apresentou características semelhantes em relação ao gênero, idade, ocorrência de diabetes mellitus e hipertensão arterial. A funcionalidade do implante, na primeira infusão, também foi semelhante para os dois grupos (83,9% para Seldinger, 79% para cirúrgico). Quando avaliada a funcionalidade em 30 dias, a técnica de Seldinger mostrou um percentual de sucesso (76,7%) maior que a técnica cirúrgica (43,6%) (P-valor=0,002). Com relação à presença de infecção e/ou sangramento no orifício de saída, o percentual foi semelhante para os dois grupos (14,8% para Seldinger, 16,9% para cirúrgico). A taxa de sobrevivência dos cateteres em 1 e 2 anos também foi semelhante para os dois grupos (37% e 14,8% para Seldinger, 23,7% e 20,6% para cirúrgico, respectivamente). Diante dos resultados, pode-se concluir que o implante de cateter peritoneal pela técnica percutânea de Seldinger é uma alternativa qualificada que permite maior agilidade ao serviço já que o procedimento é ambulatorial, pode ser realizado por nefrologistas e implica em menor manejo do paciente; apresentando funcionalidade semelhante ao implante cirúrgico conforme a experiência relatada no HUSM.
4
Moreira, Adriana Costa. "Estratificação de risco para eventos cardíacos maiores em pacientes submetidos ao implante de stents farmacológicos. Escore DESIRE." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/98/98131/tde-04102017-150207/.
Повний текст джерелаАнотація:
INTRODUÇÃO: A estratificação de risco, pré intervenção coronária percutânea, é um elemento-chave para auxiliar na tomada de decisão oferecendo o nível de expectativas de resultados imediatos e tardios. Esta investigação tem como objetivo desenvolver o escore DESIRE para predizer o risco de ocorrência de eventos cardíacos maiores(ECM) em pacientes(P) submetidos ao implante de stents farmacológicos(SF) na prática clínica diária. MÉTODOS: Desde 2002 todos os pacientes consecutivos, tratados com 1 SF , foram incluídos no Registro DESIRE (Drug-Eluting Stents In REal world), não-randomizado. Desenvolvemos o escore DESIRE, a partir da análise retrospectiva dos dados dos P incluídos entre janeiro de 2007 e dezembro de 2012 uma vez que esta população representava melhor a prática contemporânea da cardiologia intervencionista. As associações das variáveis com os eventos foram testadas pelos testes chi-quadrado e t de Student. Devido às diferenças entre as fases analisadas, decidimos por dois modelos de predição de riscos: hospitalar (Regressão logística) e tardio (Cox) estimando o tempo até o primeiro evento. Após o desenvolvimento, o escore foi aplicado prospectivamente nos pacientes incluídos entre janeiro de 2013 e dezembro de 2014. As estimativas de risco obtidas foram comparadas às taxas de ECM observadas, validando o escore DESIRE nas duas fases. RESULTADOS: 4.061 P compõem a população do estudo sendo que destes, 2.863 P constituem a coorte B1 que foi utilizada para o desenvolvimento do escore e 1.198 P na coorte B2 na qual o escore foi aplicado e validado. As variáveis e seus respectivos pontos para o escore DESIRE hospitalar que variou de 0 a 37 pontos foram: idade em anos (<=49= 0; 50 - 59=1; 60 a 69=2; 70 a 79=4; <= 80=6); cirurgia de revascularização miocárdica prévia(1); doença vascular periférica (5); insuficiência renal (3); síndrome coronária aguda (3); doença multiarterial (3); ponte de safena (6); lesão com trombo (5) e lesão longa (5). Compuseram o escore DESIRE tardio (0 a 45 pontos) as seguintes variáveis: diabete melito com medicação oral (4) ou com insulina (9); cirurgia de revascularização miocárdica prévia (2); doença vascular periférica (6); síndrome coronária aguda (5); doença multiarterial (4); FE<40% (6); ponte de safena (8) e vaso de pequeno calibre (5). Definimos 3 faixas de risco para cada um dos escores categorizando os pacientes de acordo com a pontuação obtida em baixo, intermediário e alto risco para ECM sendo para a fase hospitalar. Ambos os escores apresentaram acurácia para predizer eventos próxima a 70%. CONCLUSÃO: Baseados em dados do Registro do \"mundo real\" foi possível desenvolver o Escore DESIRE que permitiu a adequada estratificação do risco de eventos cardíacos maiores após o implante de SF, nas fases hospitalar e tardia. A partir destas estimativas de risco é possível consubstanciar as escolhas terapêuticas.BACKGROUND: Risk stratification before percutaneous coronary intervention is a key element to assist in decision making offering the level of expectations for immediate and late outcomes. This research aims to develop the DESIRE score to predict the risk of major cardiac events (MACE) in patients (P) who underwent drug-eluting stent implantation in daily clinical practice. METHODS: Since 2002 all consecutive patients treated with> 1 SF in a single center were included in the non-randomized DESIRE (Drug-Eluting Stents In the Real world) Registry. We developed the DESIRE score based on a retrospective analysis of the patients included between January 2007 and December 2012, since this population better represented the contemporary practice of interventional cardiology. The associations of the variables with the events were tested by chi-square and Student\'s t tests. Due to the differences between the analyzed phases, we decided on two models of risk prediction: hospital (Logistic Regression) and late (Cox) estimating the time until the first event. After the development, the score was applied prospectively in the patients included between January 2013 and December 2014. The risk estimates obtained were compared to the observed MACE rates, validating the DESIRE score in the two phases. RESULTS: A total of 4,061 patients were included in the study population. Of these, 2,863 P were the B1 cohort that was used for the development of the score and 1,198 P in the B2 cohort in which the score was applied and validated. The variables and their respective points for the hospital DESIRE score ranged from 0 to 37 points were: age in years <=49= 0; 50 - 59=1; 60 a 69=2; 70 a 79=4; <= 80=6); Previous myocardial revascularization surgery (1); Peripheral vascular disease (5); Cronic kidney dysfunction (3); Acute coronary syndrome (3); Multivessel disease (3) Saphenousvenous graft (6); lesion with thrombus (5) and Long lesion (5);The following variables composed the late DESIRE score (0 to 45 points): Diabetes mellitus with oral medication (4) or with insulin (9); previous myocardial revascularization surgery (2); Peripheral vascular disease (6); Acute coronary syndrome (5); Multivessel disease (4); ejection fraction <40% (6); saphenous vein graft (8) and small vessel (5). We defined 3 risk ranges for each of the scores by categorizing the patients according to the low, intermediate and high-risk scores for ECM being for the hospital phase. Both scores had accuracy to predict MACE close to 70%. CONCLUSION: Based on data from the \"real world\" registry, it was possible to develop the DESIRE score that allowed the adequate stratification of the risk of major cardiac events after the SF implantation in the hospital and late phases. From these risk estimates it is possible to substantiate the therapeutic choices.
5
Alleau, Thibaut. "Development of a numerical platform to model the mitral valve." Thesis, Compiègne, 2021. http://www.theses.fr/2021COMP2649.
Повний текст джерелаАнотація:
L’insuffisance mitrale est la valvulopathie mondiale la plus fréquente avec une prévalence de 2%. Lorsque le patient n’est pas en mesure d’être opéré à cœur ouvert, un implant percutané est utilisé pour aider la fermeture des feuillets. Le seul implant actuellement disponible est basé sur la réparation bord à bord de la valve mitrale. Il réduit le reflux vers l’oreillette lors de la systole, mais n’est pas adapté pour les patients souffrant d’insuffisance mitrale fonctionnelle, chez qui la pathologie provient du ventricule et non des éléments de la valve. L’objectif de la thèse est de fournir une plateforme numérique permettant d’aider au développement d’un implant adapté pour ces patients. Plusieurs géométries de valve ont été réalisées au moyen d’un modèle paramétrique, en utilisant des données anatomiques. La dynamique de la valve a été modélisée avec le logiciel ADINA par des simulations éléments finis en grandes déformations. Des modèles structurels de la valve ont permis de représenter la fermeture de la valve sous une pression uniforme. Les lois de comportement de matériaux ont été développé dans le but d’obtenir une fermeture réaliste de la valve. Cela a nécessité la prise en compte de l’hyperélasticité et de l’anisotropie des tissus. Des pathologies valvulaires, telles que la dilatation de l’anneau mitrale ou la rupture des cordages tendineux ont été modélisées, et plusieurs méthodes ont été testées pour y apposer des systèmes médicaux. En utilisant une description ALE et un couplage monolithique, les interactions fluide-structure ont été simulées pour une valve mitrale bi-dimensionnelle. La fermeture hermétique de la valve pendant la systole a pu être reproduite et l’ouverture de la valve étudiée pendant la diastole. La plateforme numérique développée permet de modéliser la fonction de la valve mitrale et peut être utilisée pour aider au développement d’un implant mitral grâce au modèle paramétrique reproduisant différentes géométries de valve et aux lois matériaux anisotropes. Une perspective reste la création d’un modèle 3D des interactions fluide-structure de la valve mitraleMitral insufficiency is the first valvular disease worldwide, with a 2% prevalence. When open-heartsurgery is impossible for the patient, surgeons use percutaneous devices to help the mitral leaflets coapt. However, the only device currently available is based on the edge-to-edge mitral valve repair technique. This type of implant is not adapted for patients suffering from functional mitral insufficiency, where the ventricle is responsible for the lack of coaptation of the leaflets. This thesis aims to provide a numerical platform to help the development of a mitral valve implant adapted for those patients. Several mitral valve geometries were created from a parametric model using anatomical measurements. Finite element simulations of the mitral valve were performed using ADINA to determine the valve closure under constant pressure. Several material models were developed in large strain and large deformation to model the valve closure accurately. Pathological behaviour such as annulus dilatation and chordae rupture were modelled, and several methods were tested to implement medical devices. Fluid-structure interaction of a 2D mitral valve was obtained using an ALE description and a monolithic coupling approach. Both the systole and the diastole were reproduced and studied, and the hermetic seal of the valve was detailed. The numerical platform developed is suited to model mitral valve function and can be used to help the development of mitral implants. In addition, the parametric geometry model and the anisotropic material model will be useful to depict with realism the valve function. A 3D fluid-structure interaction of the mitral valve could be developed
6
Amahzoune, Brahim. "Mise au point d’une prothèse valvulaire implantée par voie endovasculaire : effet du sertissage et déploiement sur les feuillets valvulaires et application aux voies pulmonaires dilatées." Thesis, Paris 11, 2012. http://www.theses.fr/2012PA114864/document.
Повний текст джерелаАнотація:
L’implantation valvulaire (mise en place d’une stent-valve percutanée), pulmonaire ou aortique, est une procédure récente en plein (et rapide) développement. Cette procédure prometteuse, possède plusieurs écueils parmi lesquels, l’altération du matériel implanté lors de son déploiement. L’implantation valvulaire dans les voies pulmonaires dilatées, est une autre limite de la procédure. Dans notre travail, nous avons étudié le traumatisme valvulaire lié au déploiement des prothèses. Ensuite, nous avons évalué un nouveau dispositif de réduction du calibre de la voie pulmonaire, afin d’en élargir les indications ultérieurement.Nous avons donc dans un premier temps comparé 2 types de stent-valves, l’un expansible par ballon et l’autre auto-expansible. La comparaison a porté sur l’occurrence de lésions valvulaires lors du sertissage et du déploiement de ces 2 types de prothèses. Nous avons pu montrer la présence de lésions des feuillets péricardiques de ces prothèses, induites par la compression des dispositifs. Par ailleurs, la présence de lésions histologiques plus marquées avec les valves expansibles par ballon, suggère aussi un rôle de l’expansion de ces prothèses dans la genèse des lésions valvulaires post-déploiement. Nous n’avons pas constaté d’altérations des propriétés mécaniques du tissu valvulaire induites par la compression et le déploiement des feuillets.Dans une autre partie de notre travail, nous avons mis au point un modèle d’élargissement de la voie pulmonaire, associé à la création d’une insuffisance pulmonaire sévère. Nous avons pu montrer que la réduction du calibre de la voie d’éjection pulmonaire était possible avec notre réducteur, par voie endovasculaire ou transventriculaire droite. Il n’a pas été observé de migration ou de fracture du stent de ces prothèses 2 mois après la procédure. Si le modèle d’élargissement de la voie pulmonaire est intéressant pour évaluer les réducteurs et la faisabilité de leur implantation, un suivit à plus long terme est nécessaire avant d’envisager une implantation chez l’homme. Enfin, l’altération des feuillets induite par le maniement des prothèses, est un phénomène à prendre en considération. Il nécessite, compte tenu de son impact potentiel sur la durabilité des prothèses, une investigation plus approfondiePercutaneous valve implantation (PVI) is a new with fast growing expansion procedure. Nevertheless, this promising technic has some reefs. Impairment of the implanted device at deployment is one of them. Valvular implantation in dilated right ventricular outflow tract (RVOT) is another limit of the procedure. In our work, we studied the valvular traumatism after prosthesis deployment. Subsequently, we evaluated a new device for RVOT size reduction, in order to widen PVI indications.Firstly, We compared 2 types of valved-stent (VS) (balloon expandable and self-expandable). We compared the occurrence of valvular leaflets injury after crimping and deployment of both types of prosthesis. We showed the occurrence of pericardial leaflet injuries, induced by devices crimping. Otherwise, the presence of sharp histologic lesions with balloon expandable VS, suggests a prosthesis expansion role, in genesis of valvular injuries, as well. We couldn’t show any impairment of valvular tissue mechanical properties after leaflets crimping and deployment. In another part of our work, experimental asymmetric enlargement of the RVOT with creation of severe pulmonary regurgitation, were performed in an ovine model. Size reduction of the enlarged RVOT and PVI were successfully achieved through an endovascular and right transventricular access. Valve function was satisfactory in all correctly implanted VS (one case of inversion). No migration or fractures of the size reducer or VS were seen before animal sacrifice, after 2 months follow-up. Since feasibility of RVOT enlargement and RVOT reduction has been demonstrated, a long-term study is necessary before considering a human implantation. At last but not least, deterioration on valvular leaflets after prosthesis handling is an effect to consider. Taking into account its potential impact on prosthesis durability, it requires further deep investigations
7
Büchler, Rica Dodo Delmar. "Valor prognóstico de provas funcionais na evolução tardia de pacientes com infarto agudo do miocárdio tratados com angioplastia coronária transluminal percutânea primária com implante de stent." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-21082007-111030/.
Повний текст джерелаАнотація:
Introdução: A angioplastia primária associada ao implante de stent é o tratamento de escolha no infarto agudo do miocárdio. Discute-se o valor de provas funcionais na abordagem de reestenose coronária, bem como o tempo ideal para sua realização. O objetivo deste estudo foi avaliar a importância do teste ergométrico, da cintilografia de perfusão miocárdica e do ecocardiograma bidimensional em repouso, no diagnóstico de reestenose em pacientes tratados durante as primeiras 12 horas de evolução do infarto com supra desnivelamento do segmento ST. Métodos: No período de agosto de 2003 a janeiro de 2006 foram selecionados 64 pacientes tratados com angioplastia primária e implante de stent nas primeiras 12 horas de evolução do primeiro infarto. Os pacientes realizaram ecocardiograma bidimensional em repouso, teste ergométrico com adição de derivações precordiais direitas e cintilografia de perfusão miocárdica com captação tomográfica (SPECT) sincronizada ao ECG (GATED SPECT), seis semanas (etapa1), seis meses (etapa 2) e um ano (etapa3) após a angioplastia primária. Foi realizado reestudo angiográfico no sexto mês de evolução. Resultados: A idade média foi 56,2 ±10,2 anos; 53 pacientes eram do sexo masculino. Doença uniarterial > = 50% foi observada em 46,9% dos casos. A artéria descendente anterior foi tratada em 48,4% dos pacientes, artéria coronária direita em 34,4%, artéria circunflexa em 10,9%, tronco de coronária esquerda em 3,1%,grande ramo diagonal em 1,6% e ponte safena em 1,6%. Reestenose angiográfica ocorreu em 28.8% dos 59 casos submetidos a reestudo. A fração de ejeção do ventrículo esquerdo ao ecocardiograma foi em média: 0,55 (etapa 1), 0,55 (etapa 2) e 0,56 (etapa 3). Observou-se diferença entre a fração de ejeção dos pacientes com e sem reestenose um ano após o procedimento (p=0,003). Sensibilidade, especificidade, valor preditivo positivo, valor preditivo negativo e acurácia do teste ergométrico foram respectivamente: 53,3%, 69% , 38,1%, 80,6% e 64,9% na etapa 1 (p=0,123); 54,5%, 70,7%, 33,3%, 85,3% e 67,3% na etapa 2(p=0,159) e 38,5%, 66,7%, 27,8% ,76,5% e 59,6% na etapa 3 (p=0,747). A adição de derivações precordiais direitas não elevou os índices de sensibilidade em nenhuma das etapas. Os valores de sensibilidade, especificidade, valor preditivo positivo, valor preditivo negativo e acurácía obtidos após a cintilografia de perfusão miocárdica com MIBI, quando considerada a diferença de escores entre esforço e repouso >2, foram respectivamente 40%,78,6%, 40%, 78,6% e 68,4% na etapa1(p=0,185); 54,5%,87,8%,54,5%,87,8% e 80,8% na etapa 2 (p=0,006) e 25%,91,7%,50%,78,6% e 75% na etapa 3(p=0,156). Quando considerada a diferença de escores >4 os valores foram respectivamente: 13,3%,88,1%,28,6% ,74% e 68,4% na etapa 1(p>0,999); 36,4%,95,1%,66,7%,84,8% e 82,7% na etapa 2 (p=0,014) e 8,3%,94,4 %,33,3%,75,6% e 72,9 % na etapa 3 (p >0,999). Conclusões: O teste ergométrico não permitiu discriminar reestenose na população estudada, em nenhuma das etapas durante a evolução. A cintilografia miocárdica realizada seis meses após o infarto apresentou associação com reestenose. Os pacientes com reestenose apresentaram menores valores de fração de ejeção do ventrículo esquerdo um ano após a angioplastia primária, por avaliação ecocardiográfica.Primary coronary angioplasty and stenting during acute myocardial infarction is the first treatment choice. Non-invasive testings have been used in the diagnosis of restenosis but its efficacy and time to be performed have to be determined. The purpose of this study was to evaluate exercise treadmill test, myocardial perfusion imaging and rest two-dimensional echocardiogram in the diagnosis of restenosis in patients treated during the first 12 hours of STelevation myocardial infarction.Methods: From August 2003 to January 2006, 64 patients were selected after primary coronary angioplasty and stenting. Rest two- dimensional echocardiogram, exercise treadmill test associated to right precordial leads and myocardial perfusion imaging according to GATED-SPECT were performed 6 weeks (step 1), 6 months (step 2) and one year (step 3) after the procedure.Coronary angiography was performed during the sixth month of follow-up.Results : Mean age was 56.2 ± 10.2 years; 53 patients were male. Single vessel disease > = 50% was observed in 46.9% of patients. The left anterior descending coronary artery was treated in 48.4%, the right coronary artery in 34.4%, the left circumflex in 10.9%, the left main coronary artery in 3.1%, a large diagonal branch in 1.6% and saphenous vein graft in 1.6% of the cases. Angiographic restenosis occurred in 28.8% from 59 patients submitted to coronary angiography. Mean left ventricular ejection fraction observed during rest two-dimensional echocardiogram was: 0.55 (step 1), 0.55 (step 2) and 0.56 (step 3). It was observed in patients with and without restenosis a significant difference in the left ventricular ejection fraction one year after the procedure (p= 0.003). Exercise treadmill test sensitivity, specificity, positive and negative predictive values and accuracy were respectively: 53.3%, 69%, 38.1%, 80.6% and 64.9% in step 1(p=0.123); 54.5%, 70.7%, 33.3%, 85.3% and 67.3% in step 2 (p=0.159) and 38.5%, 66.7%, 27.8%, 76.5% and 59.6% in step 3 (p=0.747). Right precordial leads did not show any additional significance. Sensitivity, specificity, positive and negative predictive values and accuracy during myocardial perfusion imaging when considering summed difference score > 2 were respectively: 40%, 78.6%, 40%, 78.6% and 68.4% in step 1(p=0.185); 54.5%, 87.8%, 54.5%,87.8% and 80.8% in step 2(p=0.006) and 25%, 91.7%, 50%, 78.6% and 75% in step 3(p=0.156). When considering summed difference score > 4 they were respectively: 13.3%, 88.1%, 28.6%, 74% and 68.4% in step 1(p> 0.999); 36.4%, 95.1%,66.7%, 84.8% and 82.7% in step 2 (p=0.014) and 8.3%, 94.4%, 33.3%, 75.6% and 72.9% in step 3(p> 0.999). Conclusions: Exercise treadmill test did not allow to discriminate restenosis in this population in all steps.Myocardial perfusion imaging performed 6 months after acute myocardial infarction was associated to restenosis. Patients with restenosis showed lower left ventricular ejection fraction one year after acute myocardial infarction by rest two-dimensional echocardiogram.
Книги з теми "Percutaneous implants"
1
Agarwal, Anil, Neil Borley, and Greg McLatchie. Urology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199608911.003.0010.
Повний текст джерелаАнотація:
This chapter on urology describes such operations as circumcision, excision of epididymal cyst, hydrocele repair, suprapubic catheter insertion, operation for testicular torsion, vasectomy, inguinal orchidectomy, transurethral resection of prostate (TURP), transurethral resection of bladder tumour (TURBT), nephrectomy, prostatectomy, pyeloplasty, cystectomy, ileal conduit diversion, penile implant, trans-obturator/transvaginal tape, and cystoplasty. Besides procedures like cystoscopy, percutaneous nephrolithotomy (PCNL), and uretoscopy are described.
Частини книг з теми "Percutaneous implants"
1
Okada, T., and Y. Ikada. "Evaluation of Collagen-Immobilized Percutaneous Implants." In Progress in Biomedical Polymers, 97–105. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4899-0768-4_11.
Повний текст джерела
2
Müller, Oliver, Sabine Donner, Tobias Klinder, Ralf Dragon, Ivonne Bartsch, Frank Witte, Alexander Krüger, Alexander Heisterkamp, and Bodo Rosenhahn. "Model Based 3D Segmentation and OCT Image Undistortion of Percutaneous Implants." In Lecture Notes in Computer Science, 454–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-23626-6_56.
Повний текст джерела
3
Morgenstern, Rudolf, and Christian Morgenstern. "New Implants and Techniques in Minimally Invasive Spine Surgery: True Percutaneous Transforaminal Lumbar Interbody Fusion (pTLIF) with the Posterolateral Transforaminal Endoscopic Approach." In Modern Thoraco-Lumbar Implants for Spinal Fusion, 69–91. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60143-4_7.
Повний текст джерела
4
Parkin, J. L. "Percutaneous Pedestal in Cochlear Implantation." In Cochlear Implant and Related Sciences Update, 279–81. Basel: KARGER, 1997. http://dx.doi.org/10.1159/000059018.
Повний текст джерела
5
Biffi, Roberto. "Choice of Venous Sites. Percutaneous Implant/Technique/US Guidance." In Totally Implantable Venous Access Devices, 55–69. Milano: Springer Milan, 2012. http://dx.doi.org/10.1007/978-88-470-2373-4_7.
Повний текст джерела
6
Auricchio, Ferdinando, Michele Conti, and Simone Morganti. "Aortic Biological Prosthetic Valve for Open-Surgery and Percutaneous Implant: Procedure Simulation and Performance Assessment." In Cardiovascular and Cardiac Therapeutic Devices, 131–68. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/8415_2013_161.
Повний текст джерела
7
Heim, F., B. Durand, and N. ChakfÉ. "Biotextiles as percutaneous heart valves." In Biotextiles as Medical Implants, 485–525. Elsevier, 2013. http://dx.doi.org/10.1533/9780857095602.2.485.
Повний текст джерела
8
"Clinical Applications of Percutaneous Implants." In High Performance Biomaterials, edited by Magnus Jacobsson and Anders TjellstrÖM, 207–30. Routledge, 2017. http://dx.doi.org/10.1201/9780203752029-15.
Повний текст джерела
9
Poole-Warren, L. A., M. D. Hallett, B. K. Milthorpe, P. C. Farrell, K. Schindhelm, M. Swain, T. W. Turney, and C. R. Howlett. "In Vivo Response to Ceramic Percutaneous Implants." In Bioceramics, 187–90. Elsevier, 1991. http://dx.doi.org/10.1016/b978-0-7506-0269-3.50029-3.
Повний текст джерела
10
Roberge, David, and Tatiana Cabrer. "Percutaneous Liver Fiducial Implants: Techniques, Materials and Complications." In Liver Biopsy in Modern Medicine. InTech, 2011. http://dx.doi.org/10.5772/21170.
Повний текст джерелаТези доповідей конференцій з теми "Percutaneous implants"
1
Holmes, Hal, Eli Vlaisavljevich, Ee Lim Tan, Keat G. Ong, and Rupak M. Rajachar. "Magnetoelastic Materials as Novel Bioactive Coatings to Improve Integration of Percutaneous Implants." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53308.
Повний текст джерелаАнотація:
Fibroblastic activity is an innate function of the host response. In the presence of many percutaneous biomedical implants, this activity becomes uncontrollable, resulting in significant fibrous overgrowth at the soft tissue-implant interface [1]. The aberrant cell growth associated with pathological fibrosis can lead to extensive remodeling and excessive synthesis of extracellular matrix (ECM) components, preventing proper integration [2]. Furthermore, these areas of irregular fibrotic activity can also serve as sites for opportunistic infection [3]. In brief, interfacial fibrosis is often responsible for the ultimate failure and increased risk of infection of percutaneous biomedical implants.
2
REED, JOEY, DREW BARNETT, and MICHAEL TODD. "“Smart” Applications for Monitoring Percutaneous, Osseointegrated Implants." In Structural Health Monitoring 2017. Lancaster, PA: DEStech Publications, Inc., 2017. http://dx.doi.org/10.12783/shm2017/14143.
Повний текст джерела
3
Jaecques, Siegfried V. N., Els De Smet, Luiza Muraru, John A. Jansen, Martine Wevers, Jos Vander Sloten, and Ignace E. Naert. "Peri-Implant Bone Adaptation Under Dynamic Mechanical Stimulation: The Guinea Pig Model." In ASME 7th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2004. http://dx.doi.org/10.1115/esda2004-58582.
Повний текст джерелаАнотація:
The present work is part of a larger project to analyse adaptive bone remodelling around implants that receive controlled mechanical stimulation immediately post-operatively. Percutaneous implants in the tibiae of guinea pigs are used as an implant model [1]. For evaluation, microfocus computed tomography (μCT) can be used to complement or partially substitute conventional histology [2]. In the studied model implant system, μCT-based histomorphometry can be used as a substitute for histology in regions at a distance of more than 1000 μm from the titanium implant. Within this limitation, a significant effect of mechanical stimulation can be observed also under in vivo μCT conditions. The optimally osteogenic stimulus in the studied model should cause a strain rate amplitude of 1600 microstrain/s or less in the cortical bone at a distance of 2.3 mm from the implant centre. Future work will include a detailed study of strains in the peri-implant bone with in vivo micro CT-based finite element models.
4
Donner, S., F. Witte, I. Bartsch, F. Petraglia, O. Massow, M. Heidrich, H. Lubatschowski, A. Heisterkamp, and A. Krüger. "In vivo optical coherence tomography of percutaneous implants in hairless mice." In BiOS, edited by Joseph A. Izatt, James G. Fujimoto, and Valery V. Tuchin. SPIE, 2010. http://dx.doi.org/10.1117/12.841640.
Повний текст джерела
5
Soares, João S., James E. Moore, and Kumbakonam R. Rajagopal. "Mechanics of Deformation-Induced Degradation of Poly(L-Lactic Acid) Endovascular Stents." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204161.
Повний текст джерелаАнотація:
Fully biodegradable polymeric stents are thought to be the third revolution in minimally invasive cardiology. After the breakthrough development of percutaneous balloon angioplasty and the dawn of the drug eluting stents era, increasing interest is being brought to the concept of temporary implants that fulfill the mission and step away.
6
Zaid, Musa B., Rosanna L. Wustrack, Matthew Garibaldi, Erik Geiger, Veronica Andaya, and Richard J. O'Donnell. "Prospective study of percutaneous bone-anchored implants in transfemoral amputees: Brain-machine platform technology for external prosthetic control and feedback." In 2019 9th International IEEE/EMBS Conference on Neural Engineering (NER). IEEE, 2019. http://dx.doi.org/10.1109/ner.2019.8716952.
Повний текст джерела
7
Korivi, Naga S., and Pratul K. Ajmera. "Percutaneous Access Device With Stress Relief Features." In ASME 2010 5th Frontiers in Biomedical Devices Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/biomed2010-32022.
Повний текст джерелаАнотація:
A polymer based percutaneous access device (PAD) has been developed to allow for a physical interconnection between an implant and the outer world during chronic animal experiments. The PAD consists of a skin-piercing conduit connected to a flat base that is typically implanted. The skin-piercing conduit has one or more circumferential notches in its walls. The stress resulting from external forces acting on the PAD conduit is concentrated at the root of the notch. This permits the conduit to bend more easily at the notch rather than at the PAD-skin interface, thereby reducing the deleterious effect of forces on the PAD-skin interface and extending the useful life of the PAD.
8
Kotzé, R., and L. Deorsola. "A Semi-Stented and Chorded Mitral Valve Prosthesis: Design and Method of Chordal Setting and In Vitro Testing." In 2018 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dmd2018-6860.
Повний текст джерелаАнотація:
Mitral subvalvular apparatus plays an important role in mitral and ventricular dynamics by preserving annuloventricular continuity, known to be fundamental for ventricular function. While some proposed mitral valve prostheses designs do attempt to account for this relationship by using papillary flaps, they are not adjustable and do not mimic the native saddle shaped mitral annulus. Unfortunately, these designs are not versatile as their papillary flap lengths cannot be altered and the prostheses are unsuitable for percutaneous implantation. We address these issues through the design of a novel semistented and chorded mitral valve that better mimics the native mitral annulus, leaflets and chordae function and can be made from off-the-shelf biomaterials with the potential to be implanted percutaneously. We also propose a novel and reliable method to set the chordal lengths individually. Finally, we demonstrate the hydrodynamic performance of the valve, showing that it meets the minimum performance requirements stipulated by the international standard ISO 5840-3:2013.
9
Calabria, André Chaves. "PALPEBRAL METASTASIS 11 YEARS AFTER DIAGNOSIS OF DUCTAL BREAST CARCINOMA." In Scientifc papers of XXIII Brazilian Breast Congress - 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s1040.
Повний текст джерелаАнотація:
Introduction: We seek to report a rare case of metastasis of infiltrating ductal carcinoma of the breast in the eyelid with a presentation 11 years after diagnosis of the primary tumor. Ocular metastasis needs to be recognized, because although it has limited survival, a timely diagnosis and treatment can significantly improve the quality of life of these patients. Case report: M.S.V., female, 59 years old, presented with locally advanced right breast cancer, clinical stage T3N1M0, with a histopathological diagnosis of infiltrating ductal carcinoma by percutaneous biopsy in 2008. Initially submitted to neoadjuvant chemotherapy, with complete clinical and histopathological response. Then, radical mastectomy was performed with right axillary lymphadenectomy and immediate breast reconstruction associated with contralateral breast symmetrization; adjuvant radiotherapy and hormone therapy with tamoxifen. She would be a carrier of pathogenic variant heterozygous BRCA 2, but preferred not to perform other risk-reducing therapies. Shee had a favorable evolution, with good therapeutic response, and continued to undergo periodic clinical and imaging exams, without changes. In 2019, she presented right eyelid ptosis, with a diagnosis of eyelid tumor. Complementary exams with evidence of an infiltrative lesion with mild expansive effect on magnetic resonance imaging of the orbit; secondary implants in the frontal region of the skull evidenced in bone scintigraphy and magnetic resonance imaging; in addition to high AC 15.3 = 274.42. A biopsy of the eyelid lesion was performed, with histopathological results of metastatic adenocarcinoma of breast origin and an immunohistochemical panel with the presence of estrogen receptor, Ki67 5%, no expression of HER2 and progesterone receptor, in addition to the presence of GATA3. Currently under treatment with Fulvestrant. The case infers great importance, due to the rarity of the metastatic site, which indicates a poor prognosis. Furthermore, it appeared more than twice it was expected after detection of the primary tumor. Although rare, these lesions can be the first sign of systemic disease.
10
Sun, Wei, and Milton DeHerrera. "Modeling the Interaction Between the Coronary Sinus and the Proximal Anchor Stent in Percutaneous Transvenous Mitral Annuloplasty." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19715.
Повний текст джерелаАнотація:
Surgical treatment of severe functional mitral regurgitation (MR) often involves mitral annuloplasty, a procedure where a flexible or rigid annuloplasty ring is used to downsize the dilated mitral valve annulus (MA) and improve leaflet apposition by posterior annular correction. Recently various minimally invasive percutaneous transvenous mitral annuloplasty (PTMA) devices have been tested in patients who are not suitable candidates for a surgical procedure involving a thoracotomy. The approach is based on the concept that by utilizing the parallel location of the coronary sinus (CS) to the mitral annulus, a device, that can reshape the annulus, can be percutaneously deployed within the coronary sinus (CS) and the great cardiac vein (GCV). When the implanted device deforms, it shortens the MA anterior-posterior dimension and decreases mitral regurgitation (MR) (Fig. 1). Although the approach has been shown to be promising, PTMA device dysfunction and fatigue fracture have been reported in several firstin-human clinical trials (1). We hypothesize that quantitative understanding of the biomechanical interaction between the venous tissue, the mitral improve the efficacy of the PTMA treatment of MR. In this study, we aim to model interactions between the PTMA proximal anchor and the CS using computational tools.