Статті в журналах з теми "Peptide Prodrugs"
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Zhang, Richard, and Haishan Lin. "Abstract 5204: Optimization of novel anti-human CD47 antibody prodrugs as cancer therapeutics with low on-target toxicity." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5204. http://dx.doi.org/10.1158/1538-7445.am2022-5204.
Повний текст джерелаTHOMAS, W. A. "Peptide derivatives as prodrugs." Biochemical Society Transactions 14, no. 2 (April 1, 1986): 383–87. http://dx.doi.org/10.1042/bst0140383.
Повний текст джерелаMcKenna, Charles E., Boris A. Kashemirov, Ulrika Eriksson, Gordon L. Amidon, Phillip E. Kish, Stefanie Mitchell, Jae-Seung Kim, and John M. Hilfinger. "Cidofovir peptide conjugates as prodrugs." Journal of Organometallic Chemistry 690, no. 10 (May 2005): 2673–78. http://dx.doi.org/10.1016/j.jorganchem.2005.03.004.
Повний текст джерелаJanssen, Samuel, Carsten M. Jakobsen, D. Marc Rosen, Rebecca M. Ricklis, Ulrich Reineke, Soeren B. Christensen, Hans Lilja, and Samuel R. Denmeade. "Screening a combinatorial peptide library to develop a human glandular kallikrein 2–activated prodrug as targeted therapy for prostate cancer." Molecular Cancer Therapeutics 3, no. 11 (November 1, 2004): 1439–50. http://dx.doi.org/10.1158/1535-7163.1439.3.11.
Повний текст джерелаForde, Éanna, Hilary Humphreys, Catherine M. Greene, Deirdre Fitzgerald-Hughes, and Marc Devocelle. "Potential of Host Defense Peptide Prodrugs as Neutrophil Elastase-Dependent Anti-Infective Agents for Cystic Fibrosis." Antimicrobial Agents and Chemotherapy 58, no. 2 (November 25, 2013): 978–85. http://dx.doi.org/10.1128/aac.01167-13.
Повний текст джерелаForde, Eanna, and Marc Devocelle. "Pro-Moieties of Antimicrobial Peptide Prodrugs." Molecules 20, no. 1 (January 13, 2015): 1210–27. http://dx.doi.org/10.3390/molecules20011210.
Повний текст джерелаForde, Éanna, André Schütte, Emer Reeves, Catherine Greene, Hilary Humphreys, Marcus Mall, Deirdre Fitzgerald-Hughes, and Marc Devocelle. "DifferentialIn VitroandIn VivoToxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis." Antimicrobial Agents and Chemotherapy 60, no. 5 (February 22, 2016): 2813–21. http://dx.doi.org/10.1128/aac.00157-16.
Повний текст джерелаWei, Yaoming, and Dehua Pei. "Activation of antibacterial prodrugs by peptide deformylase." Bioorganic & Medicinal Chemistry Letters 10, no. 10 (May 2000): 1073–76. http://dx.doi.org/10.1016/s0960-894x(00)00167-0.
Повний текст джерелаLee, Jiyoun, Wei Huang, James M. Broering, Annelise E. Barron, and Jiwon Seo. "Prostate tumor specific peptide–peptoid hybrid prodrugs." Bioorganic & Medicinal Chemistry Letters 25, no. 14 (July 2015): 2849–52. http://dx.doi.org/10.1016/j.bmcl.2015.04.092.
Повний текст джерелаFreeman, Hanna, Selvi Srinivasan, Debobrato Das, Patrick S. Stayton, and Anthony J. Convertine. "Fully synthetic macromolecular prodrug chemotherapeutics with EGFR targeting and controlled camptothecin release kinetics." Polymer Chemistry 9, no. 42 (2018): 5224–33. http://dx.doi.org/10.1039/c8py01047a.
Повний текст джерелаWong, Daniel Yuan Qiang, Jun Han Lim, and Wee Han Ang. "Induction of targeted necrosis with HER2-targeted platinum(iv) anticancer prodrugs." Chemical Science 6, no. 5 (2015): 3051–56. http://dx.doi.org/10.1039/c5sc00015g.
Повний текст джерелаTewari, K. M., E. Yaghini, O. Reelfs, R. Dondi, C. Pourzand, A. J. MacRobert, and I. M. Eggleston. "Peptide-targeted prodrugs for aminolaevulinic acid photodynamic therapy." Photodiagnosis and Photodynamic Therapy 17 (March 2017): A60. http://dx.doi.org/10.1016/j.pdpdt.2017.01.135.
Повний текст джерелаYang, Seong-Bin, Nipa Banik, Bomin Han, Dong-Nyeong Lee, and Jooho Park. "Peptide-Based Bioconjugates and Therapeutics for Targeted Anticancer Therapy." Pharmaceutics 14, no. 7 (June 29, 2022): 1378. http://dx.doi.org/10.3390/pharmaceutics14071378.
Повний текст джерелаLangley, Emma, Chen Li, Jessica Zaid, Tani-Ann Lee, Deepak Yadav, Brian Grot, Jay Singh, and Johnovan Kim. "713 Novel protease activatable linker with tumor targeting motifs enhances the retention of cytokine prodrug and active cytokine at disease site and demonstrates improved efficacy in preclinical model." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (November 2021): A742. http://dx.doi.org/10.1136/jitc-2021-sitc2021.713.
Повний текст джерелаWANG, HUI-PO, HSIAO-HWA LU, JIA-SHUAI LEE, CHIH-YUAN CHENG, JIN-RAN MAH, CHING-YI KU, WENLIE HSU, CHEN-FANG YEN, CHUN-JUNG LIN та HARNG S. KUO. "Intestinal Absorption Studies on Peptide Mimetic α-Methyldopa Prodrugs". Journal of Pharmacy and Pharmacology 48, № 3 (березень 1996): 270–76. http://dx.doi.org/10.1111/j.2042-7158.1996.tb05915.x.
Повний текст джерелаHenrique Goulart Trossini, Gustavo, Chung Man Chin, Carla Maria de Souza Menezes, and Elizabeth Igne Ferreira. "Molecular Modeling Suggests Cruzain Specificity for Peptide Primaquine Prodrugs." Letters in Drug Design & Discovery 7, no. 7 (August 1, 2010): 528–33. http://dx.doi.org/10.2174/157018010791526287.
Повний текст джерелаPalandoken, Hasan, Kolbot By, Manu Hegde, William R. Harley, Fredric A. Gorin, and Michael H. Nantz. "Amiloride Peptide Conjugates: Prodrugs for Sodium-Proton Exchange Inhibition." Journal of Pharmacology and Experimental Therapeutics 312, no. 3 (October 27, 2004): 961–67. http://dx.doi.org/10.1124/jpet.104.076984.
Повний текст джерелаBourré, Ludovic, Francesca Giuntini, Ian M. Eggleston, Michael Wilson, and Alexander J. MacRobert. "5-Aminolaevulinic acid peptide prodrugs enhance photosensitization for photodynamic therapy." Molecular Cancer Therapeutics 7, no. 6 (June 2008): 1720–29. http://dx.doi.org/10.1158/1535-7163.mct-08-0092.
Повний текст джерелаNollmann, Friederike Inga, Tina Goldbach, Nicole Berthold, and Ralf Hoffmann. "Kontrollierte systemische Freisetzung therapeutischer Peptide aus PEGylierten Prodrugs durch Serumproteasen." Angewandte Chemie 125, no. 29 (June 13, 2013): 7747–50. http://dx.doi.org/10.1002/ange.201301533.
Повний текст джерелаAgarwal, Sheetal, S. H. S. Boddu, Ritesh Jain, Swapan Samanta, Dhananjay Pal, and Ashim K. Mitra. "Peptide prodrugs: Improved oral absorption of lopinavir, a HIV protease inhibitor." International Journal of Pharmaceutics 359, no. 1-2 (July 2008): 7–14. http://dx.doi.org/10.1016/j.ijpharm.2008.03.031.
Повний текст джерелаBACKWELL, F. R. C., D. T. ELMORE, and C. H. WILLIAMS. "The use of neuropeptidases to release drug from peptide-based prodrugs." Biochemical Society Transactions 16, no. 2 (April 1, 1988): 214–15. http://dx.doi.org/10.1042/bst0160214a.
Повний текст джерелаWeiss, William J., Susan M. Mikels, Peter J. Petersen, Nilda V. Jacobus, Panayota Bitha, Yang-I. Lin та Raymond T. Testa. "In Vivo Activities of Peptidic Prodrugs of Novel Aminomethyl Tetrahydrofuranyl-1β-Methylcarbapenems". Antimicrobial Agents and Chemotherapy 43, № 3 (1 березня 1999): 460–64. http://dx.doi.org/10.1128/aac.43.3.460.
Повний текст джерелаCooper, Itzik, Michal Schnaider-Beeri, Mati Fridkin, and Yoram Shechter. "Albumin–Methotrexate Prodrug Analogues That Undergo Intracellular Reactivation Following Entrance into Cancerous Glioma Cells." Pharmaceutics 14, no. 1 (December 28, 2021): 71. http://dx.doi.org/10.3390/pharmaceutics14010071.
Повний текст джерелаCho, Hanhee, Man Kyu Shim, Suah Yang, Sukyung Song, Yujeong Moon, Jinseong Kim, Youngro Byun, Cheol-Hee Ahn, and Kwangmeyung Kim. "Cathepsin B-Overexpressed Tumor Cell Activatable Albumin-Binding Doxorubicin Prodrug for Cancer-Targeted Therapy." Pharmaceutics 14, no. 1 (December 29, 2021): 83. http://dx.doi.org/10.3390/pharmaceutics14010083.
Повний текст джерелаLi, Xuejiao, Yahong Liu, and Hongqi Tian. "Current Developments in Pt(IV) Prodrugs Conjugated with Bioactive Ligands." Bioinorganic Chemistry and Applications 2018 (October 1, 2018): 1–18. http://dx.doi.org/10.1155/2018/8276139.
Повний текст джерелаWang, Binghe, Wei Wang, Huijuan Zhang, Daxian Shan, and Terrill D. Smith. "Coumarin-based prodrugs 2. Synthesis and bioreversibility studies of an esterase-sensitive cyclic prodrug of dadle, an opioid peptide." Bioorganic & Medicinal Chemistry Letters 6, no. 23 (December 1996): 2823–26. http://dx.doi.org/10.1016/s0960-894x(96)00526-4.
Повний текст джерелаJanoria, Kumar G., Sai H. S. Boddu, Subramanian Natesan, and Ashim K. Mitra. "Vitreal Pharmacokinetics of Peptide-Transporter-Targeted Prodrugs of Ganciclovir in Conscious Animals." Journal of Ocular Pharmacology and Therapeutics 26, no. 3 (June 2010): 265–71. http://dx.doi.org/10.1089/jop.2009.0123.
Повний текст джерелаSchmid, Björn, André Warnecke, Iduna Fichtner, Manfred Jung, and Felix Kratz. "Development of Albumin-Binding Camptothecin Prodrugs Using a Peptide Positional Scanning Library." Bioconjugate Chemistry 18, no. 6 (November 2007): 1786–99. http://dx.doi.org/10.1021/bc0700842.
Повний текст джерелаNasrolahi Shirazi, Amir, Rakesh Tiwari, Bhupender S. Chhikara, Dindyal Mandal, and Keykavous Parang. "Design and Biological Evaluation of Cell-Penetrating Peptide–Doxorubicin Conjugates as Prodrugs." Molecular Pharmaceutics 10, no. 2 (January 15, 2013): 488–99. http://dx.doi.org/10.1021/mp3004034.
Повний текст джерелаEriksson, Ulrika, Larryn W. Peterson, Boris A. Kashemirov, John M. Hilfinger, John C. Drach, Katherine Z. Borysko, Julie M. Breitenbach, et al. "Serine Peptide Phosphoester Prodrugs of Cyclic Cidofovir: Synthesis, Transport, and Antiviral Activity." Molecular Pharmaceutics 5, no. 4 (May 16, 2008): 598–609. http://dx.doi.org/10.1021/mp8000099.
Повний текст джерелаDe, Arnab, and Richard D. DiMarchi. "Synthesis and characterization of ester-based prodrugs of glucagon-like peptide 1." Biopolymers 94, no. 4 (June 30, 2010): 448–56. http://dx.doi.org/10.1002/bip.21418.
Повний текст джерелаMatošević, Ana, and Anita Bosak. "Carbamate group as structural motif in drugs: a review of carbamate derivatives used as therapeutic agents." Archives of Industrial Hygiene and Toxicology 71, no. 4 (December 1, 2020): 285–99. http://dx.doi.org/10.2478/aiht-2020-71-3466.
Повний текст джерелаWang, Caihong, Chu Chu, Xiang Ji, Guoliang Luo, Chunling Xu, Houhong He, Jianbiao Yao, Jian Wu, Jiangning Hu, and Yuanxiang Jin. "Biology of Peptide Transporter 2 in Mammals: New Insights into Its Function, Structure and Regulation." Cells 11, no. 18 (September 14, 2022): 2874. http://dx.doi.org/10.3390/cells11182874.
Повний текст джерелаOuyang, Liang, Wencai Huang, Gu He, and Li Guo. "Bone Targeting Prodrugs Based on Peptide Dendrimers, Synthesis and Hydroxyapatite Binding In Vitro." Letters in Organic Chemistry 6, no. 4 (June 1, 2009): 272–77. http://dx.doi.org/10.2174/157017809788489981.
Повний текст джерелаChin, Chung, Diego Chiba, Marcella Machado, Ednir Vizioli, and Jean Santos. "Peptide Prodrugs for the Treatment of CNS Disorders: A Perspective for New Drugs." Current Medicinal Chemistry 21, no. 23 (February 17, 2014): 2599–609. http://dx.doi.org/10.2174/0929867321666140217125526.
Повний текст джерелаPoreba, Marcin. "Recent advances in the development of legumain-selective chemical probes and peptide prodrugs." Biological Chemistry 400, no. 12 (December 18, 2019): 1529–50. http://dx.doi.org/10.1515/hsz-2019-0135.
Повний текст джерелаGiuntini, Francesca, Ludovic Bourré, Alexander J. MacRobert, Michael Wilson, and Ian M. Eggleston. "Improved Peptide Prodrugs of 5-ALA for PDT: Rationalization of Cellular Accumulation and Protoporphyrin IX Production by Direct Determination of Cellular Prodrug Uptake and Prodrug Metabolization." Journal of Medicinal Chemistry 52, no. 13 (July 9, 2009): 4026–37. http://dx.doi.org/10.1021/jm900224r.
Повний текст джерелаRoseeuw, Eveline, Veerle Coessens, Anne-Marie Balazuc, Micheline Lagranderie, Pierre Chavarot, Augusto Pessina, Maria Grazia Neri, Etienne Schacht, Gilles Marchal, and Dominique Domurado. "Synthesis, Degradation, and Antimicrobial Properties of Targeted Macromolecular Prodrugs of Norfloxacin." Antimicrobial Agents and Chemotherapy 47, no. 11 (November 2003): 3435–41. http://dx.doi.org/10.1128/aac.47.11.3435-3441.2003.
Повний текст джерелаHu, Zilun, Xiangjun Jiang, Charles F. Albright, Nilsa Graciani, Eddy Yue, Mingzhu Zhang, Shu-Yun Zhang, et al. "Discovery of matrix metalloproteases selective and activated peptide–doxorubicin prodrugs as anti-tumor agents." Bioorganic & Medicinal Chemistry Letters 20, no. 3 (February 2010): 853–56. http://dx.doi.org/10.1016/j.bmcl.2009.12.084.
Повний текст джерелаPolykandritou, Athina, Alexandra Serre, Hannah Spencer, Goreti R. Morais, Amanda Race, Steven Shnyder, Paul Loadman, and Robert A. Falconer. "Abstract 1074: Cellular uptake and metabolism of MT1-MMP-activated taxane prodrugs." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1074. http://dx.doi.org/10.1158/1538-7445.am2022-1074.
Повний текст джерелаOliyai, Reza, and Valentino J. Stella. "Structural Factors affecting the kinetics of O,N-acyl transfer in potential O-peptide prodrugs." Bioorganic & Medicinal Chemistry Letters 5, no. 22 (November 1995): 2735–40. http://dx.doi.org/10.1016/0960-894x(95)00454-2.
Повний текст джерелаShaik, Imam H., Hitesh K. Agarwal, Keykavous Parang, and Reza Mehvar. "Hepatic immunosuppressive effects of systemically administered novel dextran–methylprednisolone prodrugs with peptide linkers in rats." Journal of Pharmaceutical Sciences 101, no. 10 (October 2012): 4003–12. http://dx.doi.org/10.1002/jps.23274.
Повний текст джерелаFriis, Gitte Juel, Annette Bak, Bjarne Due Larsen, and Sven Frøkjær. "Prodrugs of peptides obtained by derivatization of the C-terminal peptide bond in order to effect protection against degradation by carboxypeptidases." International Journal of Pharmaceutics 136, no. 1-2 (June 1996): 61–69. http://dx.doi.org/10.1016/0378-5173(95)04481-7.
Повний текст джерелаKumar, Ritesh, Amrish Chandra, and Pawan Kumar Gautam. "Modified Approaches for Colon Specific Drug Delivery System: A Review." Indian Journal of Pharmaceutical and Biological Research 1, no. 03 (September 30, 2013): 67–79. http://dx.doi.org/10.30750/ijpbr.1.3.12.
Повний текст джерелаProkai-Tatrai, Katalin, Vien Nguyen, Alevtina D. Zharikova, April C. Braddy, Stanley M. Stevens, and Laszlo Prokai. "Prodrugs to enhance central nervous system effects of the TRH-like peptide pGlu-Glu-Pro-NH2." Bioorganic & Medicinal Chemistry Letters 13, no. 6 (March 2003): 1011–14. http://dx.doi.org/10.1016/s0960-894x(03)00081-7.
Повний текст джерелаSaaby, L., C. U. Nielsen, B. Steffansen, S. B. Larsen, and B. Brodin. "Current status of rational design of prodrugs targeting the intestinal di/tri-peptide transporter hPEPT1 (SLC15A1)." Journal of Drug Delivery Science and Technology 23, no. 4 (2013): 307–14. http://dx.doi.org/10.1016/s1773-2247(13)50047-5.
Повний текст джерелаAloysius, Herve, and Longqin Hu. "Synthesis and evaluation of new peptide-linked doxorubicin conjugates as prodrugs activated by prostate-specific antigen." Medicinal Chemistry Research 29, no. 7 (June 4, 2020): 1280–99. http://dx.doi.org/10.1007/s00044-020-02573-w.
Повний текст джерелаWu, Xinghua, and Longqin Hu. "Design and synthesis of peptide conjugates of phosphoramide mustard as prodrugs activated by prostate-specific antigen." Bioorganic & Medicinal Chemistry 24, no. 12 (June 2016): 2697–706. http://dx.doi.org/10.1016/j.bmc.2016.04.035.
Повний текст джерелаVerhulst, Emile, Delphine Garnier, Ingrid De Meester, and Brigitte Bauvois. "Validating Cell Surface Proteases as Drug Targets for Cancer Therapy: What Do We Know, and Where Do We Go?" Cancers 14, no. 3 (January 26, 2022): 624. http://dx.doi.org/10.3390/cancers14030624.
Повний текст джерелаKwant, Kathryn, Sony Rocha, Katrina Stephenson, Maria Dayao, Subramanian Thothathri, Rose Banzon, Wade Aaron, et al. "867 TriTAC-XR is an extended-release T cell engager platform designed to minimize cytokine release syndrome by reducing Cmax in systemic circulation." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (November 2021): A908. http://dx.doi.org/10.1136/jitc-2021-sitc2021.867.
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