Добірка наукової літератури з теми "Patient-derived organoids"
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Статті в журналах з теми "Patient-derived organoids"
Maier, Christopher Fabian, Lei Zhu, Lahiri Kanth Nanduri, Daniel Kühn, Susan Kochall, May-Linn Thepkaysone, Doreen William, et al. "Patient-Derived Organoids of Cholangiocarcinoma." International Journal of Molecular Sciences 22, no. 16 (August 12, 2021): 8675. http://dx.doi.org/10.3390/ijms22168675.
Повний текст джерелаLee, Chansu, Sung-Noh Hong, Eun-Ran Kim, Dong-Kyung Chang, and Young-Ho Kim. "Epithelial Regeneration Ability of Crohn’s Disease Assessed Using Patient-Derived Intestinal Organoids." International Journal of Molecular Sciences 22, no. 11 (June 2, 2021): 6013. http://dx.doi.org/10.3390/ijms22116013.
Повний текст джерелаWeeber, Fleur, Marc van de Wetering, Marlous Hoogstraat, Krijn K. Dijkstra, Oscar Krijgsman, Thomas Kuilman, Christa G. M. Gadellaa-van Hooijdonk, et al. "Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases." Proceedings of the National Academy of Sciences 112, no. 43 (October 12, 2015): 13308–11. http://dx.doi.org/10.1073/pnas.1516689112.
Повний текст джерелаValeri, Nicola. "Abstract IA010: Patient derived organoids in precision oncology." Cancer Research 82, no. 23_Supplement_1 (December 1, 2022): IA010. http://dx.doi.org/10.1158/1538-7445.crc22-ia010.
Повний текст джерелаMcQueeney, Kelley E., Patrick Bhola, Sarah J. Hill, and Anthony Letai. "Abstract 4309: Early apoptotic measurements of patient-derived organoids predict patient response to therapy." Cancer Research 83, no. 7_Supplement (April 4, 2023): 4309. http://dx.doi.org/10.1158/1538-7445.am2023-4309.
Повний текст джерелаSondorp, Luc H. J., Vivian M. L. Ogundipe, Andries H. Groen, Wendy Kelder, Annelies Kemper, Thera P. Links, Robert P. Coppes, and Schelto Kruijff. "Patient-Derived Papillary Thyroid Cancer Organoids for Radioactive Iodine Refractory Screening." Cancers 12, no. 11 (October 31, 2020): 3212. http://dx.doi.org/10.3390/cancers12113212.
Повний текст джерелаKoedoot, Esmee, Inez van Weersch, Gakuro Harada, Masahiko Watanabe, Hamdy Warda, Hideaki Kyan, Yasmine Abouleila, et al. "Abstract 157: Patient in the lab: Down-scaling patient-derived organoid screening for diagnostic purposes." Cancer Research 83, no. 7_Supplement (April 4, 2023): 157. http://dx.doi.org/10.1158/1538-7445.am2023-157.
Повний текст джерелаCostales-Carrera, Alba, Asunción Fernández-Barral, Pilar Bustamante-Madrid, Orlando Domínguez, Laura Guerra-Pastrián, Ramón Cantero, Luis del Peso, Aurora Burgos, Antonio Barbáchano, and Alberto Muñoz. "Comparative Study of Organoids from Patient-Derived Normal and Tumor Colon and Rectal Tissue." Cancers 12, no. 8 (August 15, 2020): 2302. http://dx.doi.org/10.3390/cancers12082302.
Повний текст джерелаVerissimo, Carla S., Lidwien Smabers, Emerens Wensink, Esmee Koedoot, Maarten Huismans, Celia Higuera Barón, Ricardo Korporaal, et al. "Abstract 4112: Patient derived organoids predict clinical response: A patient in the lab." Cancer Research 82, no. 12_Supplement (June 15, 2022): 4112. http://dx.doi.org/10.1158/1538-7445.am2022-4112.
Повний текст джерелаPernik, Mark N., Cylaina E. Bird, Jeffrey I. Traylor, Diana D. Shi, Timothy E. Richardson, Samuel K. McBrayer, and Kalil G. Abdullah. "Patient-Derived Cancer Organoids for Precision Oncology Treatment." Journal of Personalized Medicine 11, no. 5 (May 17, 2021): 423. http://dx.doi.org/10.3390/jpm11050423.
Повний текст джерелаДисертації з теми "Patient-derived organoids"
Raimondi, Giulia. "Broadening Adenoviral Oncolysis in PDAC: Interrogation of Patient-Derived Organoids for personalized virotherapy and modulation of miRNA content to boost adenoviral potency." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/671205.
Повний текст джерелаSeitlinger, Joseph. "Optimisation d’un modèle d’organoïde de cancer du poumon vascularisé dérivé de patient à des fins de médecine de précision." Electronic Thesis or Diss., Strasbourg, 2022. http://www.theses.fr/2022STRAJ022.
Повний текст джерелаDespite numerous recent advances, lung cancer is the leading cause of cancer mortality worldwide. Every year, new therapeutic drugs are developed to fight this disease whose prognosis remains poor. The development of precision medicine should make it possible to improve its effectiveness. In this perspective, we have optimized an organoid model derived from lung cancer patients. In this work, we were able to show that our model is reproducible and that it mimics the patient's tumor. Finally, the formation of a vascular network at the level of the organoid is possible : it can infiltrate the formed organoid but can also grow from the organoid to infiltrate the microenvironment. The model that we put forward thus meets the specifications of a patient Avatar model. The tests of therapeutic drugs or irradiation that we are currently carrying out will allow us to define if this model is compatible with a future use in clinical practice to improve the management of patients diagnosed with lung cancer
Morice, Pierre-Marie. "Evaluation de la déficience de la recombinaison homologue et de la réponse des tumeurs ovariennes aux inhibiteurs de PARP grâce à l'utilisation de modèles de culture 3D en vue du développement d'un test prédictif Identifying eligible patients to PARP inhibitors: from NGS-based tests to promising 3D functional assays Automated scoring for assessment of RAD51-mediated homologous recombination in patient-derived tumor organoids of ovarian cancers Risk of myelodysplastic syndrome and acute myeloid leukemia related to PARP inhibitors: a combined approach using a safety meta-analysis of placebo randomized controlled trials and the World Health Organization's pharmacovigilance database The long non-coding RNA ‘UCA1’ modulates the response to chemotherapy of ovarian cancer through direct binding to miR-27a-5p and control of UBE2N levels." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMC414.
Повний текст джерелаWorldwide each year, more than 150 000 women die from epithelial ovarian cancer largely due to emergence of resistance to chemotherapy. Approximately half of these cancers display molecular alterations that cause deficiency of DNA repair via homologous recombination (HRD), which confer sensitivity to PARP protein inhibitors (PARPi). To date, there is no test capable of fully identifying the HRD phenotype, thus limiting access to these treatments. In this context, we are developing functional assays based on the use of tumor explant slices and then, on the use of tumor organoids derived from ovarian tumors of chemotherapy-naive or previously treated patients. The culture of explants was unsuitable for this application and we then focused our work on tumor organoids. Tumor organoids were exposed to carboplatin (first-line treatment) and two PARP inhibitors (olaparib and niraparib) used for maintenance therapy. In parallel, we collected clinical data from patients (survival, platinum-free interval, RECIST, treatments) to evaluate the predictive potential of these models. The established tumor organoids responded heterogeneously to different drugs, and our results show that the organoid-based assay is capable of identifying patients highly resistant to carboplatin, suggesting that this functional assay could have a predictive value for patients treated with carboplatin. Regarding the potential of organoids in predicting PARPi response, multiple sensitivity profiles have been identified, but the correlation with clinical response has yet to be determined by studies conducted on tumor samples from patients treated with these drugs
Johansson, Seiko. "Patient-derived organoid culture for 3D culture of colorectal cancer, renal cancer and osteosarcoma." Thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-391043.
Повний текст джерелаYamamoto, Takehito. "Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263523.
Повний текст джерелаGRASSI, LUDOVICA. "Development of preclinical models for Renal Cell Carcinoma." Doctoral thesis, 2018. http://hdl.handle.net/11573/1086689.
Повний текст джерелаЧастини книг з теми "Patient-derived organoids"
Kdimati, Said, Florian Bürtin, Michael Linnebacher, and Christina Susanne Mullins. "Patient-Derived Organoids for In Vivo Validation of In Vitro Data." In Methods in Molecular Biology, 111–26. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2788-4_8.
Повний текст джерелаTu, Mei-Juan, Colleen M. Yi, Gavin M. Traber, and Ai-Ming Yu. "Bioengineered RNA Therapy in Patient-Derived Organoids and Xenograft Mouse Models." In Methods in Molecular Biology, 191–206. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2441-8_10.
Повний текст джерелаSoroka, Carol J., David N. Assis, and James L. Boyer. "Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies." In Methods in Molecular Biology, 363–72. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9420-5_24.
Повний текст джерелаGreen, Sara, Mie S. Dam, and Mette N. Svendsen. "Patient-Derived Organoids in Precision Oncology – Towards a Science of and for the Individual?" In Personalized Medicine in the Making, 125–46. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-74804-3_7.
Повний текст джерелаLefferts, Juliet W., Vera Boersma, Marne C. Hagemeijer, Karima Hajo, Jeffrey M. Beekman, and Erik Splinter. "Targeted Locus Amplification and Haplotyping." In Methods in Molecular Biology, 31–48. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2819-5_2.
Повний текст джерелаBurkhart, Richard A., Lindsey A. Baker, and Hervé Tiriac. "Testing Susceptibility of Patient-Derived Organoid Cultures to Therapies: Pharmacotyping." In Methods in Molecular Biology, 253–61. New York, NY: Springer New York, 2018. http://dx.doi.org/10.1007/978-1-4939-7847-2_19.
Повний текст джерелаMariappan, Aruljothi, Theda Knauth, Roberto Pallini, and Jay Gopalakrishnan. "A Three-Dimensional Organoid Culture System to Model Invasive Patterns of Patient-Derived Glioma Stem Cells." In Neuromethods, 139–58. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2720-4_8.
Повний текст джерелаFeng, Liang, Wenmei Yang, Hui Zhao, Jamie Bakkum-Gamez, Mark E. Sherman, and Nagarajan Kannan. "Protocol for the Detection of Organoid-Initiating Cell Activity in Patient-Derived Single Fallopian Tube Epithelial Cells." In Methods in Molecular Biology, 445–54. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1979-7_30.
Повний текст джерелаMukherjee, Anubhab, Aprajita Sinha, Maheshree Maibam, Bharti Bisht, and Manash K. Paul. "Organoids and Commercialization." In Organoids [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104706.
Повний текст джерелаWang, Jia, Xiaoying Feng, Zhichao Li, Yongsong Chen, and Weiren Huang. "Patient-derived organoids as a model for tumor research." In Progress in Molecular Biology and Translational Science. Elsevier, 2022. http://dx.doi.org/10.1016/bs.pmbts.2022.03.004.
Повний текст джерелаТези доповідей конференцій з теми "Patient-derived organoids"
Verduin, M., A. Hoeben, L. Ackermans, D. Eekers, C. Hubert, J. Rich, V. Tjan-Heijnen, and M. Vooijs. "PO-340 Tumour heterogeneity in patient-derived glioblastoma organoids." In Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June – 3 July 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/esmoopen-2018-eacr25.852.
Повний текст джерелаCalandrini, Camilla, Frans Schutgens, Rurika Oka, Thanasis Margaritis, Tito Candelli, Luka Mathijsen, Carola Ammerlaan, et al. "Abstract IA27: Patient-derived organoids in pediatric cancer research." In Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.pedca19-ia27.
Повний текст джерелаRen, Xiaoyu. "The culture and application of patient-derived tumour organoids." In International Conference on Biological Engineering and Medical Science (ICBIOMed2022), edited by Gary Royle and Steven M. Lipkin. SPIE, 2023. http://dx.doi.org/10.1117/12.2669049.
Повний текст джерелаPuca, Loredana, Rohan Bareja, Reid Shaw, Wouter Karthaus, Dong Gao, Chantal Pauli, Juan Miguel Mosquera, et al. "Abstract 992: Patient-derived tumor organoids of neuroendocrine prostate cancer." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-992.
Повний текст джерелаRosati, Rachele, Hallie A. Swan, Laura Scolaro, Kateryna Krytska, John M. Maris, Franz X. Schaub, and Carla Grandori. "Abstract 2625: Patient derived organoids to guide personalized neuroblastoma treatment." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2625.
Повний текст джерелаKim, Seok-Young, Dong Hwi Kim, Hyeong-Seok Joo, Mi Ran Yun, Ji Yeon Lee, Sang Min Kim, Hyunki Kim, Min Hee Hong, Hye Ryun Kim, and Byoung Chul Cho. "Abstract 38: NSCLC patient-derived organoids to guide personalized therapy." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-38.
Повний текст джерелаKim, Seok-Young, Dong Hwi Kim, Hyeong-Seok Joo, Mi Ran Yun, Ji Yeon Lee, Sang Min Kim, Hyunki Kim, Min Hee Hong, Hye Ryun Kim, and Byoung Chul Cho. "Abstract 38: NSCLC patient-derived organoids to guide personalized therapy." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-38.
Повний текст джерелаSpiller, Erin, Roy Lau, Sarah Choung, and Shannon M. Mumenthaler. "Abstract A18: High-content 3D image analysis of patient-derived organoids." In Abstracts: Patient-Derived Cancer Models: Present and Future Applications from Basic Science to the Clinic; February 11-14, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1557-3265.pdx16-a18.
Повний текст джерелаKarkampouna, Sofia, Federico la Manna, Maria R. De Filippo, Mirjam Kiener, Marta De Menna, Eugenio Zoni, Joel Grosjean, et al. "Abstract B18: Patient-derived xenograft and organoids models of prostate cancer." In Abstracts: AACR Special Conference on the Evolving Landscape of Cancer Modeling; March 2-5, 2020; San Diego, CA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.camodels2020-b18.
Повний текст джерелаKhan, Syamantak, June Ho Shin, Ning Cheng, Calvin Kuo, John Sunwoo, and Guillem Pratx. "Abstract B08: High-resolution positron emission microscopy of patient-derived tumor organoids." In Abstracts: AACR Special Conference on the Evolving Landscape of Cancer Modeling; March 2-5, 2020; San Diego, CA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.camodels2020-b08.
Повний текст джерела