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1
Soares, Nair Castro. "António Beccadelli, El Panormita, Dichos y hechos de Alfonso, rey de Aragón.(Discurso de Alfonso con motivo de la expedición contra los Turcos. El triunfo Alfonsino)." Humanitas 66 (December 10, 2014): 436–39. http://dx.doi.org/10.14195/2183-1718_66_24.
Повний текст джерелаАнотація:
António Beccadelli, El Panormita, Dichos y hechos de Alfonso, rey de Aragón. (Discurso de Alfonso con motivo de la expedición contra los Turcos. El triunfo Alfonsino). Edición de Santiago López Moreda. Akal. Clásicos Latinos Medievales y Renascentistas. Madrid, 2014.http://dx.doi.org/10.14195/2183-1718_66_24
2
Galera Hernàndez, Rubén. "Estudi de les fonts d’una Epistula de amore d’Antonio Beccadelli adreçada al valencià Francesc de Centelles (1437-1442) sobre la «vis, aut potestas» de l’amor." SCRIPTA. Revista Internacional de Literatura i Cultura Medieval i Moderna 12 (December 21, 2018): 220. http://dx.doi.org/10.7203/scripta.12.13673.
Повний текст джерелаАнотація:
Resum: La política expansionista de la Corona d’Aragó vers el Mezzogiorno italià, encapçalada per Alfons el Magnànim durant la primera meitat del segle XV, va suposar que el monarca formara al seu voltant una cort d’humanistes italians perquè deixaren constància escrita de la seua empresa i transmeteren a la seua cort els coneixements dels grans autors clàssics llatins i grecs. Aquesta nòmina de lletraferits en estudis grecollatins, en què trobem Lorenzo Valla, Guiniforte Barzizza, Bartolomeo Facio i Antonio Beccadelli (el Panormita), entre d’altres, mantingueren assíduament contacte amb membres de la cancelleria reial i de la noblesa. Un d’aquests nobles va ser el cavaller valencià, camarlenc, conseller i mariscal, Francesc-Gilabert de Centelles i Queralt, altrament dit Ramon de Riu-sec, senyor de Nules i comte d’Oliva (1449), qui va mantenir correspondència epistolar amb Barzizza i Beccadelli, per demanar-los consell sobre la naturalesa de l’amor. En aquest article, doncs, hem estudiat les fonts de consulta a què va recórrer el Panormita quan va redactar l’epístola i el contextualitzem amb la realitat amorosa del cavaller valencià.
Paraules clau: segle XV, Itàlia, Corona d’Aragó, Antonio Beccadelli, Francesc-Gilabert de Centelles.
Abstract: The expansionist policy of the Crown of Aragon towards the Italian Mezzogiorno, headed by Alfons el Magnànim during the first half of the fifteenth century, supposed that the monarch would form around him a court of Italian humanists for the written testimony of his enterprise and the transmition to the court of the knowledge of the great Latin and Greek classical authors. This list of letters written in Greco-Latin studies, in which we find Lorenzo Valla, Guiniforte Barzizza, Bartolomeo Facio and Antonio Beccadelli (Panormita), among others, were always in contact with members of the Royal Chancery and the nobility. One of these nobles was the Valencian knight, chamberlain, counselor and marshal, Francesc-Gilabert de Centelles i Queralt, otherwise known as Ramon de Riu-sec, lord of Nules and Count of Oliva (1449), who corresponded with Barzizza and Beccadelli, to ask for advice about the nature of love. In this article, we have studied the sources of reference that Panormita consulted when writing the epistle and we contextualize it with the loving reality of the Valencian knight.
Keywords: 15th century, Italy, Crown of Aragon, Antonio Beccadelli, Francesc-Gilabert de Centelles.
3
Heyworth, S. J. "Notes on Propertius, Books III and IV." Classical Quarterly 36, no. 1 (May 1986): 199–211. http://dx.doi.org/10.1017/s000983880001065x.
Повний текст джерелаАнотація:
I offer further notes on the text of Propertius. In the apparatusΩis employed to indicate the archetype, i.e. the consensus of N and two separate groups of humanistic manuscripts that I denote by the lettersΠandΛ. TheΠMSS (FLP) derive from a lost manuscript of Petrarch, itself copied from the manuscript A (which is not extant after 2.1.63). TheΛMSS are largely a group isolated by J. L. Butrica (The Manuscript Tradition of Propertius, Phoenixsuppl. vol. 17, Toronto, 1984, 62–95), which derive from a third medieval source discovered by Poggio and brought to Italy, apparently in 1423. The oldestΛmanuscript is Vat. lat. 3273, copied by Panormita in Florence in 1427, here called T. Another independent descendant is S (Monacensis Univ. Cim. 22), written in Florencec.1460 by Poggio's son Jacopo. Three other Florentine copies of the 1460s descend from a single source later thanΛ: M (Paris. B. N. lat. 8233, formerlyμ); U (Vat. Urb. lat. 641, formerlyυ); and R (Bodmer. 141, once Abbey 5989). Butrica would cite also C (Romanus Casanatensis 15), written by Pomponio Letoc.1470; but its witness is vitiated by the frequency both of error and of interpolation and its presence would confuse rather than clarify our picture ofΛ. On the other hand I include the pair J (Parmensis Palat. Parm. 140, Florence,c.1440) and K (Vratislauiensis Univ. Akc. 1948 KN 197, Padua 1469).
4
Sparacio, Ignazio, and Salvatore Surdo. "New data on Calomera panormitana panormitana (Ragusa, 1906) in Sicily (Coleoptera Cicindelidae)." Biodiversity Journal 12, no. 4 (December 30, 2021): 1027–34. http://dx.doi.org/10.31396/biodiv.jour.2021.12.2.1027.1034.
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5
Reeve, M. D. "Plautus, Pontano and Panormita - Rita Cappelletto: La ‘Lectura Plauti' del Pontano. Con edizione delle postille del cod. Vindob. Lat. 3168 e osservazioni sull’ ‘Itala recensio’ (Ludus Philologiae, 2.) Pp. 295; 28 plates. Urbino: Quattro Venti, 1988. Paper, L. 35,000." Classical Review 40, no. 1 (April 1990): 24–27. http://dx.doi.org/10.1017/s0009840x00251950.
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6
BRETT, MARTIN. "Some New Letters of Popes Urban II and Paschal II." Journal of Ecclesiastical History 58, no. 1 (January 2007): 75–96. http://dx.doi.org/10.1017/s0022046906008888.
Повний текст джерелаАнотація:
The ancient library of the canons of St Peter at the Vatican contained two copies of the Panormia, an immensely successful canon law collection attributed to Ivo of Chartres.1 Neither was part of the legacy of Cardinal Giordano Orsini (d. 1438), and they may well have been at St Peter's since the later twelfth century when they were written. In spite of the many losses the library suffered, both survive, as MS G 19 and MS G 19bis.2
7
Arcidiacono, Myriam, Caterina Catalano, Antonio Motisi, Maurizio Sajeva, Francesco Carimi, and Angela Carra. "Influence of Culture Conditions on In Vitro Asymbiotic Germination of Anacamptis longicornu and Ophrys panormitana (Orchidaceae)." Plants 10, no. 11 (November 22, 2021): 2543. http://dx.doi.org/10.3390/plants10112543.
Повний текст джерелаАнотація:
This study is the first approach to in vitro asymbiotic germination of two species of Sicilian threatened terrestrial orchids, Anacamptis longicornu and Ophrys panormitana. Seeds were collected in the wild and cultured in two different media—Orchimax medium (OM) and Murashige and Skoog (MS)—and exposed to different photoperiods and temperatures to evaluate the best conditions for the specific stages of development. The germination of A. longicornu was very high on OM (95.5%) and lower on MS medium (21.4%), whereas O. panormitana germinated only on OM medium, with significantly lower percentages (12.0%), compared with A. longicornu. This difference is caused by variation in quality and quantity of nutrients used, primarily by nitrogen source. The results show that temperature and photoperiod widely affect seed germination and development. Although further investigations on asymbiotic and symbiotic germination are needed for the improvement of conservation of Mediterranean terrestrial orchids, our results contribute to the conservation of this group of plants.
8
Gianguzzi, Lorenzo, and Giuseppe Bazan. "The vegetation of a historic road system in the suburban area of Monte Pellegrino (Palermo, Sicily)." Plant Sociology 57, no. 2 (November 20, 2020): 71–103. http://dx.doi.org/10.3897/pls2020572/02.
Повний текст джерелаАнотація:
Knowledge of the processes by which plants colonize old structures is a key element for nature-based design both in urban and suburban contexts. This paper analyses the natural vegetation on walls and in other microhabitats of the roadway structures of Monte Pellegrino (606 m a.s.l.) near Palermo (Sicily), built in the first half of the 1900s. The historical road has particular construction and architectural features, and its characteristics have been maintained to this day. The route, approximately 16 kilometers long, is well integrated within a site of high naturalistic value which has been designated as a Special Area of Conservation (ITA020014) of the Natura 2000 network, and it is also a regional natural reserve. The survey was carried out on different homogeneous ecological contexts based on different microhabitats (masonry retaining walls, masonry guardwalls, road margins, and rock cut slopes) which are diversified according to other environmental factors (building materials, inclination, height, and exposure). The phytosociological and statistical analysis has led to the description of six new associations (Crepido bursifoliae-Parietarietum judaicae ass. nov., Athamanto siculae-Parietarietum judaicae ass. nov., Helichryso panormitani-Hypochaeridetum laevigatae ass. nov., Diantho siculi-Helichrysetum panormitani Gianguzzi ass. nov., Olopto miliacei-Pennisetetum setacei Gianguzzi ass. nov., Teucrio flavi-Rhoetum coriariae Gianguzzi ass. nov.) and one sub-association (Rhamno alaterni-Euphorbietum dendroidis Géhu & Biondi 1997 artemisietosum arborescentis subass. nov.). Other chasmophytic formations (Centranthetum rubri Oberd. 1969, Antirrhinetum siculi Bartolo & Brullo 1986) were reported for the first time in this area.
9
O'Connor, Eugene. "Panormita's Reply to His Critics: The Hermaphroditus and the Literary Defense." Renaissance Quarterly 50, no. 4 (1997): 985–1010. http://dx.doi.org/10.2307/3039402.
Повний текст джерелаАнотація:
In her discussion of Imitatio, Julia Haig Gaisser describes how humanist scholars and poets justified their light, titillating compositions, based on Catullus, Martial, and The Priapea, by invoking the ancient literary defense, whose purpose was essentially to ward off potential critics or else to justify their oeuvre by making a sharp distinction between their life and their art. One locus classicus is Catullus 16.5-6: “Nam castum esse decet pium poetam/ ipsum, versiculos nihil necesse est” (The devoted poet ought to be chaste himself, his verses need not be so). Another is Martial, Epigrams 1.4.8, which, modeled as it is on Ovid, Tristia 2.354, speaks not of poets in general but of Martial himself: “Lasciva est nobis pagina, vita proba“ (My writing is lascivious, my life pure). The classical defensio or apologia was thus revived and given new meaning by the humanists as they sought to justify their literary endeavors in light of an emerging and ultimately puritanical sense of decorum.
10
Austin, Greta. "III. Editorial concerns in the Ivonian Panormia: the case of repetitious canons in book 8." Zeitschrift der Savigny-Stiftung für Rechtsgeschichte: Kanonistische Abteilung 89, no. 1 (August 1, 2003): 82–106. http://dx.doi.org/10.7767/zrgka.2003.89.1.82.
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11
Salvadó, Sebastián. "The Augustinian Reform, the Panormia Glosses, and Reading the Bible in the Medieval Latin Liturgy of Jerusalem." Revue d'Etudes Augustiniennes et Patristiques 62, no. 1 (January 2016): 27–55. http://dx.doi.org/10.1484/j.rea.4.2017005.
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12
Condorelli, Orazio. "XI. La dottrina delle fonti del diritto nel Commentario del Panormitano sulla Distinctio prima del Decretum." Zeitschrift der Savigny-Stiftung für Rechtsgeschichte: Kanonistische Abteilung 91, no. 1 (August 1, 2005): 299–354. http://dx.doi.org/10.7767/zrgka.2005.91.1.299.
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13
Argubi, Adi Hidayat, Ruli Inayah Ramadhoan, and Hendra Hendra. "PENGEMBANGAN MARINE TOURISM BERBASIS ECOTOURISM DI PULAU NISA/KAMBING KOTA BIMA NTB." Sadar Wisata: Jurnal Pariwisata 3, no. 2 (December 24, 2020): 116–29. http://dx.doi.org/10.32528/sw.v3i2.3883.
Повний текст джерелаАнотація:
Penelitian ini bertujuan menganalisis potensi pengembangan marine tourism berbasis ecotourism di PulauNisa/Kambing Kota Bima NTB, serta mengkaji daya dukung dan partisipasi masyarakat. Jenis penelitian yang digunakan adalah jenis penelitian deskriptif kualitatif dengan teknik pengumpulan data penelitian yang digunakan antara lain: observasi,wawancara berstruktur, studi kepustakaan dan kuesioner. Dalam penelitian ini populasinyaa dalah masyarakat Kelurahan Tanjung Kecamatan Rasanae Barat Kota Bima serta wisatawan berkunjung dengan masing – masing 100 responden. Sedangkan analisis data menggunakan analisis deskriptif dan Analisis SWOT. Hasil penelitian menunjukkan bahwa Pulau Nisa/Kambing memiliki kekuatan untuk menjadi daerah tujuan wisata unggulan Kota Bima pada aspek keindahan alam (panorama), panorma bawah laut, kebudayaan masyarakat sekitar, aksessibilitas yang mudah dijangkau, sumber daya manusia serta daya dukung masyarakat dan wisatawan yang memberikan peluang pengembangan. Sedangkan kelemahannya seperti kurangnya promosi, kemampuan SDM pariwisata, fasilitas pendukung terlihat masih minim.
14
Di Stefano, Piero, and Daniela Ruberti. "Cenomanian rudist-dominated shelf-margin limestones from the panormide carbonate platform (Sicily, Italy): Facies analysis and sequence stratigraphy." Facies 42, no. 1 (January 2000): 133–60. http://dx.doi.org/10.1007/bf02562570.
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15
Batista, Gustavo Araújo. "Montaigne: A educação sob perspectiva do cepticismo intelectual e do estoicismo moral no Renascimento." EccoS – Revista Científica, no. 39 (December 18, 2015): 147–66. http://dx.doi.org/10.5585/eccos.n39.5289.
Повний текст джерелаАнотація:
Sob perspectiva educacional, a filosofia de Michel Eyquem de Montaigne (1533-1592) oferece a possibilidade de uma pedagogia pautada no ceticismo intelectual e no estoicismo moral, uma vez que, segundo o ensasta francs, em sendo impossvel a aquisio do conhecimento definitivo ou inquestionvel, restaria apenas a busca incessante por algo que seja, ao menos, um pouco mais confivel ou provvel, da mesma forma que seria imperativo educar o indivduo para uma conduta virtuosa e implacvel no cumprimento do dever moral. Nesse nterim, o objetivo deste artigo, que se justifica na necessidade de aproximar a filosofia e a educao, demonstrar a aplicabilidade do pensamento filosfico de Montaigne reflexo educacional, oferecendo, para isso, uma viso panormica do contexto histrico ao qual pertence, isto , o Renascimento, assim como da sua obra magna (Ensaios), dela extraindo elementos para a compreenso da sua filosofia em geral e, em particular, da contribuio de suas reflexes para uma fundamentao filosfica da educao, sob perspectiva ctica e estoica. Como resultado, apresenta-se que o cepticismo intelectual e o estoicismo moral de Montaigne permanecem como alertas contra possveis enganos, erros, iluses ou equvocos causados por concepes que no fazem questionar at que ponto o saber confivel, do mesmo modo que fazem ignorar a importncia da formao da conduta humana. Espera-se que estas consideraes no tocante s ideias filosficas e educacionais de Montaigne, vinculadas ao seu contexto histrico, possam suscitar reflexes sobre a problemtica da fundamentao terica da educao, em prol de uma prtica pedaggica que usufrua das contribuies tericas oferecidas pela filosofia.
16
FALZONE, Emmanuël. "Panormitain et la séparation de corps pour « incompatibilité d’humeur » : l’influence d’un décrétaliste italien dans la jurisprudence d’un official cambrésien ?" Publications du Centre Européen d'Etudes Bourguignonnes 49 (January 2009): 259–85. http://dx.doi.org/10.1484/j.pceeb.1.100466.
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Basilone, Luca, Francesco Perri, Attilio Sulli, and Salvatore Critelli. "Paleoclimate and extensional tectonics of short-lived lacustrine environments. Lower Cretaceous of the Panormide Southern Tethyan carbonate platform (NW Sicily)." Marine and Petroleum Geology 88 (December 2017): 428–39. http://dx.doi.org/10.1016/j.marpetgeo.2017.08.041.
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18
Cramer, Peter. "Ernulf of Rochester and Early Anglo-Norman Canon Law." Journal of Ecclesiastical History 40, no. 4 (October 1989): 483–510. http://dx.doi.org/10.1017/s002204690005898x.
Повний текст джерелаАнотація:
Ernulf, bishop of Rochester, died aged eighty-four, on 15 March 1124. In the course of his life, he studied under Lanfranc and was a close friend of Anselm at Bec. One-time prior of Christ Church, Canterbury, his advice was apparently sought by the king; he became a much respected abbot of Peterborough; and, as bishop, he instigated the important collection of secular and ecclesiastical law, the Textus Roffensis. Of his own writing, only three letters survive: one to Anselm, pleading with him to return from exile; one to the monk Lambert of St-Bertin, answering four questions on the eucharist and a fifth concerning a passage from the prophet Joel; and the third to Walkelin of Winchester, dealing with the case of canon law which the two men had previously discussed. It is this last letter, appearing in the manuscripts with the title De incestis coniugiis, which makes of Ernulf something more than a shadow among the Anglo-Norman theologians and men of letters who came to England in the aftermath of conquest. It is in this letter-treatise that Ernulf emerges as an accomplished lawyer and juridical thinker, whose approach has departed radically from that of Lanfranc, his former teacher, and is closely comparable to the principles for legal judgement set down by Ivo of Chartres in the preface to his Decretum and Panormia. Ernulf's use of such methods, grounded in, and made possible by, the new systematic collections of canon law, helps to confirm what has already begun to be evident, that this systematic, deliberately and self-consciously rational, jurisprudence finds its way into England well before the dissemination of Gratian's Decretum in the mid-twelfth century.
19
Dewever, B., I. Berwouts, R. Swennen, L. Breesch, and R. M. Ellam. "Fluid flow reconstruction in karstified Panormide platform limestones (north-central Sicily): Implications for hydrocarbon prospectivity in the Sicilian fold and thrust belt." Marine and Petroleum Geology 27, no. 4 (April 2010): 939–58. http://dx.doi.org/10.1016/j.marpetgeo.2009.10.018.
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20
Basilone, Luca. "Synsedimentary tectonics vs paleoclimatic changes across the Aptian-Albian boundary along the Southern Tethyan margin: The panormide carbonate platform case history (NW Sicily)." Marine and Petroleum Geology 124 (February 2021): 104801. http://dx.doi.org/10.1016/j.marpetgeo.2020.104801.
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Basilone, Luca, Attilio Sulli, and Maurizio Gasparo Morticelli. "Integrating facies and structural analyses with subsidence history in a Jurassic–Cretaceous intraplatform basin: Outcome for paleogeography of the Panormide Southern Tethyan margin (NW Sicily, Italy)." Sedimentary Geology 339 (June 2016): 258–72. http://dx.doi.org/10.1016/j.sedgeo.2016.03.017.
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22
Farbaky, Péter. "Giovanni d’Aragona (1456‒1485) szerepe Mátyás király mecénásságában." Művészettörténeti Értesítő 70, no. 1 (March 17, 2022): 47–91. http://dx.doi.org/10.1556/080.2021.00002.
Повний текст джерелаАнотація:
King Matthias Corvinus of Hungary (1458‒1490), son of the “Scourge of the Turks,” John Hunyadi, was a foremost patron of early Renaissance art. He was only fourteen years old in 1470 when he was elected king, and his patronage naturally took some time and maturity to develop, notably through his relations with the Neapolitan Aragon dynasty. In December 1476, he married Beatrice, daughter of Ferdinand of Aragon, who brought to Buda a love of books and music she had inherited from her grandfather, Alphonse of Aragon.I studied the work of Beatrice’s brother John of Aragon (Giovanni d’Aragona), previously known mainly from Thomas Haffner’s monograph on his library (1997), from the viewpoint of his influence on Matthias’s art patronage. John was born in Naples on June 25, 1456, the third son of Ferdinand I of Aragon. His father, crowned king by Pope Pius II in 1458 following the death of Alphonse of Aragon, intended from the outset that he should pursue a church career. Ferdinand’s children, Alphonse (heir to the throne), Beatrice, and John were educated by outstanding humanist teachers, including Antonio Beccadelli (Il Panormita) and Pietro Ranzano. Through his father and the kingdom’s good relations with the papacy, John acquired many benefices, and when Pope Sixtus IV (1471‒1484) created him cardinal at the age of twenty-one, on December 10, 1477, he made a dazzling entrance to Rome. John was — together with Marco Barbo, Oliviero Carafa, and Francesco Gonzaga — one of the principal contemporary patrons of the College of Cardinals.On April 19, 1479, Sixtus IV appointed John legatus a latere, to support Matthias’s planned crusade against the Ottomans. On August 31, he departed Rome with two eminent humanists, Raffaele Maffei (also known as Volaterranus), encyclopedist and scriptor apostolicus of the Roman Curia, and Felice Feliciano, collector of ancient Roman inscriptions. John made stops in Ferrara, and Milan, and entered Buda — according to Matthias’s historian Antonio Bonfini — with great pomp. During his eight months in Hungary, he accompanied Matthias and Beatrice to Visegrád, Tata, and the Carthusian monastery of Lövöld and probably exerted a significant influence on the royal couple, particularly in the collecting of books. Matthias appointed his brother-in-law archbishop of Esztergom, the highest clerical office in Hungary, with an annual income of thirty thousand ducats.Leaving Hungary in July 1480, John returned to Rome via Venice and Florence, where, as reported by Ercole d’Este’s ambassador to Florence, Lorenzo de’ Medici showed him the most valuable works of art in his palace, and he visited San Marco and its library and the nearby Medici sculpture garden.In September 1483, Sixtus IV again appointed John legate, this time to Germany and Hungary. He took with him the Veronese physician Francesco Fontana and stayed in Buda and Esztergom between October 1483 and June 1484. The royal couple presented him with silver church vessels, a gold chalice, vestments, and a miter.John’s patronage focused on book collecting and building. He spent six thousand ducats annually on the former. Among his acquisitions were contemporary architectural treatises by Leon Battista Alberti and Filarete, which he borrowed for copying from Lorenzo’s library. They were also featured in Matthias Corvinus’s library, perhaps reflecting John’s influence. Around 1480, during his stay in Buda (approximately 1478‒1480), the excellent miniaturist, Francesco Rosselli made the first few large-format luxury codices for Matthias and Beatrice. Both Queen Beatrice and John of Aragon played a part of this by bringing with them the Aragon family’s love of books, and perhaps also a few codices. The Paduan illuminator Gaspare da Padova (active 1466‒1517), who introduced the all’antica style to Neapolitan book painting, was employed in Rome by John as well as by Francesco Gonzaga, and John’s example encouraged Matthias and Beatrice commission all’antica codices. He may also have influenced the choice of subject matter: John collected only ancient and late classical manuscripts up to 1483 and mainly theological and scholastic books thereafter; Matthias’s collection followed a similar course in which theological and scholastic works proliferated after 1485. Anthony Hobson has detected a link between Queen Beatrice’s Psalterium and the Livius codex copied for John of Aragon: both were bound by Felice Feliciano, who came to Hungary with the Cardinal. Feliciano’s probable involvement with the Erlangen Bible (in the final period of his work, probably in Buda) may therefore be an important outcome of the art-patronage connections between John and the king of Hungary.John further shared with Matthias a passion for building. He built palaces for himself in the monasteries of Montevergine and Montecassino, of which he was abbot, and made additions to the cathedral of Sant’Agata dei Goti and the villa La Conigliera in Naples. Antonio Bonfini, in his history of Hungary, highlights Matthias’s interest, which had a great impact on contemporaries; but only fragments of his monumental constructions survive.We see another link between John and Matthias in the famous goldsmith of Milan, Cristoforo Foppa (Caradosso, c. 1452‒1526/1527). Caradosso set up his workshop in John’s palace in Rome, where he began but — because of his patron’s death in autumn 1485 — was unable to finish a famous silver salt cellar that he later tried to sell. John may also have prompted Matthias to invite Caradosso to spend several months in Buda, where he made silver tableware.Further items in the metalware category are our patrons’ seal matrices. My research has uncovered two kinds of seal belonging to Giovanni d’Aragona. One, dating from 1473, is held in the archives of the Benedictine Abbey of Montecassino. It is a round seal with the arms of the House of Aragon at the centre. After being created cardinal in late 1477, he had two types of his seal. The first, simple contained only his coat of arm (MNL OL, DL 18166). The second elaborate seal matrix made in the early Renaissance style, of which seals survive in the Archivio Apostolico Vaticano (Fondo Veneto I 5752, 30 September 1479) and one or two documents in the Esztergom Primatial Archive (Cathedral Chapter Archive, Lad. 53., Fasc. 3., nr.16., 15 June 1484). At the centre of the mandorla-shaped field, sitting on a throne with balustered arm-rest and tympanum above, is the Virgin Mary (Madonna lactans type), with two supporting figures whose identification requires further research. The legend on the seal is fragmentary: (SIGILL?)VM ……….DON IOANNIS CARDINALIS (D’?) ARAGONIA; beneath it is the cardinal’s coat of arms in the form of a horse’s head (testa di cavallo) crowned with a hat. It may date from the time of Caradosso’s first presumed stay in Rome (1475‒1479), suggesting him as the maker of the matrix, a hypothesis for which as yet no further evidence is known to me. The seals of King Matthias have been thoroughly studied, and the form and use of each type have been almost fully established.John of Aragon was buried in Rome, in his titular church, in the Dominican Basilica of Santa Sabina. Johannes Burckard described the funeral procession from the palace to the Aventine in his Liber notarum. Matthias died in 1490 in his new residence, the Vienna Burg, and his body was taken in grand procession to Buda and subsequently to the basilica of Fehérvár, the traditional place of burial of Hungarian kings. The careers of both men ended prematurely: John might have become pope, and Matthias Holy Roman emperor.(The bulk of the research for this paper was made possible by my two-month Ailsa Mellon Bruce Visiting Senior Fellowship at the Center for Advanced Study in the Visual Arts [CASVA] of the National Gallery of Art [Washington DC] in autumn 2019.) [fordította: Alan Campbell]
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Basilone, Luca, and Attilio Sulli. "Basin analysis in the Southern Tethyan margin: Facies sequences, stratal pattern and subsidence history highlight extension-to-inversion processes in the Cretaceous Panormide carbonate platform (NW Sicily)." Sedimentary Geology 363 (January 2018): 235–51. http://dx.doi.org/10.1016/j.sedgeo.2017.11.013.
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Chari, Ajai, Hearn J. Cho, Samir Parekh, Amishi Dhadiwal, Katarzyna Garcia, Natalie Belostotsky, Donna Catamero, et al. "A Phase II, Single-Center, Open-Label Study of Oral Panobinostat in Combination with Lenalidomide and Weekly Dexamethasone in Patients with Multiple Myeloma." Blood 124, no. 21 (December 6, 2014): 3486. http://dx.doi.org/10.1182/blood.v124.21.3486.3486.
Повний текст джерелаАнотація:
Abstract Background: Treatment options for patients with multiple myeloma (MM) refractory (ref) to immunomodulatory drugs and proteasome inhibitors are urgently needed. A promising strategy is the use of epigenetic agents such as the pan histone deacetylase inhibitor (HDACi) panobinostat (pan) to modulate the acetylation of histones and proteins involved in oncogenesis. Pre-clinical studies with pan demonstrate synergy against MM cells when combined with dexamethasone (dex), lenalidomide (len), and bortezomib (btz) (Ocio EM et al. Haematologica 2010). Interim data from the phase 3 PANORMA 1 study of 768 patients randomized to receive IV btz and dex with either pan or placebo revealed a 3.9 month increase in PFS with pan along with an increase in CR rates. However, this was accompanied by 25% grade 3/ 4 diarrhea versus 8% in the placebo arm. The safety and preliminary efficacy of the pan-len-dex triplet regimen was assessed in a phase 1b study of relapsed (rel) or rel/ref MM patients (Mateos et al, ASCO 2010) but was complicated by high dose dex toxicities. The maximum tolerated dose of pan and dex in that study are the doses selected for this phase 2 study. However we investigated a modified schedule (table 1) of this triplet regimen. Here, pan is given thrice weekly only every other week (instead of weekly) and dex is given weekly (instead of three 4 day pulses). Patients and Methods: Inclusion criteria were patients with rel or rel/ref MM, measurable disease, adequate performance status, organ function, and hematologic parameters. Patients previously treated with a HDACI or currently receiving medications with a risk of prolonging the QTc interval were excluded. The primary objective was to evaluate the best overall response rate (ORR). Secondary objectives were to evaluate safety, response duration, and overall and progression-free survival. Each drug was administered at the doses and schedule shown in Table 1. Results: Overall, 13 evaluable patients with progressive disease (PD) at screening have been enrolled, including 9 len-refractory (2 also pomalidomide refractory) and 4 len sensitive with a median of 4 and 3 lines of prior therapy respectively (range 1–10). High-risk molecular findings were present in 9 patients, including 6 with gain of 1q21 by FISH and 3 with del p53. Three of the patients with gain of 1q21 also had t (4;14). Of the 13 patients, there have been 3 very good partial responses (VGPR), 2 partial responses (PR), 3 minimal responses (MR), 4 stable diseases (SD), and 1 PD, for an ORR of 38% and clinical benefit rate (CBR i.e. MR or greater) of 61 %. With a median follow up of 4.5 months the median progression free survival and duration of response have not been reached. Of the 9 patients who were len refractory, there were 2 VGPR, 2 MRs, 4 SD, and 1 PD for a 22% ORR and 44% CBR. Notably, 3 len refractory patients remain on treatment for 11, 16, and 16 months including 2 with gain of 1q21 that have attained VGPRs. Grade 3/4 toxicities (regardless of drug attribution) were primarily hematologic, with neutropenia, thrombocytopenia, lymphopenia, and anemia noted in 7, 4, 1, and 1 patients respectively. Grade 3/4 nonhematologic AEs included infections in 4 (with 1 one occurring while neutropenic), and 1 patient with each of the following: pulmonary embolus, neck pain, QTc prolongation, and weight loss 1. Dose modifications for neutropenia were required in 4 patients for len and in 2 patients for pan. 1 additional patient required pan dose reduction for asymptomatic T wave inversions. Nausea was noted in 2 patients and diarrhea in 3 with 2 additional patients experiencing both – however these were transient, Grade 1/2, and did not require dose modifications. Importantly, no patients discontinued therapy for toxicity. Conclusions: In rel/ref MM patients, pan in combination with len and dex demonstrates durable responses, even in len-refractory patients with high-risk molecular findings, indicating the essential role of pan in attaining a response. These results suggest that pan modulates expression of genes to restore sensitivity to len, In notable contrast to the PANORMA 1 results, this completely oral regimen is well tolerated with no Grade 3/4 GI toxicities and primarily expected hematologic toxicities. Updated results, including correlative studies, will be presented at the annual meeting. Table 1: Study Drug Doses Panobinostat Lenalidomide Dexamethasone 20 mg po Day 1, 3, 5, 15, 17,19 25 mg po Day 1-21 40 mg po Day 1, 8, 15 Disclosures Chari: Array Biopharma: Membership on an entity's Board of Directors or advisory committees; Millenium : Consultancy, Membership on an entity's Board of Directors or advisory committees; Celgene: Consultancy, Membership on an entity's Board of Directors or advisory committees. Jagannath:Celgene: Honoraria; Millennium: Honoraria; Sanofi: Honoraria.
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Chari, Ajai, Hearn Jay Cho, Siyang Leng, Amishi Dhadwal, Gillian Morgan, Lisa La, Katarzyna Garcia, et al. "A Phase II Study of Panobinostat with Lenalidomide and Weekly Dexamethasone in Myeloma." Blood 126, no. 23 (December 3, 2015): 4226. http://dx.doi.org/10.1182/blood.v126.23.4226.4226.
Повний текст джерелаАнотація:
Abstract Background: Treatment options for multiple myeloma (MM) refractory (ref) to immunomodulatory drugs (IMID) and proteasome inhibitors (PI) are urgently needed. Epigenetic agents e.g. the pan histone deacetylase inhibitor (HDACi) panobinostat (pan) to modulate the acetylation of histones and oncogenic proteins are promising. Preclinically in MM, pan is syngeristic when combined with dexamethasone (dex), lenalidomide (len), and bortezomib (btz) (Ocio EM et al. Haematologica 2010). The phase 3 PANORMA 1 study of 768 patients randomized to receive IV btz and dex with either pan or placebo revealed a 3.9 month increase in PFS and increased CR rates with pan but at the cost of an increase in grade 3/4 diarrhea from 8% to 25% (San Miguel, Lancet 2014). The safety/preliminary efficacy of pan-len-dex was assessed in a phase 1b study (Mateos et al, ASCO 2010) but was complicated by high dose dex toxicities. The maximum tolerated doses were used for this phase 2 study, however, we attenuated the schedule so that pan is given thrice weekly every other week (instead of weekly) and dex is given only weekly (table 1). Methods: Inclusion criteria were patients with rel or rel/ref MM (including IMID/PI ref), measurable disease, adequate organ function and hematologic parameters. Patients previously treated with a HDACi or currently receiving QTC prolonging medications were excluded. The primary objective in this open label, single arm phase 2 study was to evaluate the best overall response rate (ORR). Secondary objectives were to evaluate safety, duration of response (DOR), and overall and progression-free survival (PFS). Each drug was administered at the doses and schedule shown in Table 1. Results: 26 evaluable patients with progressive disease (PD) at screening have been enrolled with a median age of 64 (44% > 65 yo) and a median of 2 lines of therapy over 4 years since diagnosis. High-risk molecular findings were present in 14 patients (54%), including 4 with del p53 and 10 with gain of 1q21 by FISH (4 with concurrent t(4;14)). 22 (85%) were len- ref, & 35, 54, 23% were ref to each: pomalidomide (pom), btz, & carfilzomib. Responses include 2 complete responses (CR), 4 very good partial responses (VGPR), 4 PRs, 9 minimal responses (MR), and 3 stable diseases (SD), for an ORR of 38%, CBR (>MR) of 73%, and a median DOR of 6 mos. The median PFS was 6.5 mos. In the 22 len-ref pts, there were 4 VGPRs, 2 PRs, 8 MRs & 3 SDs, with a median PFS of 5.5 mos. Responses were even seen in 10 pom-ref pts including 1 VPGR, 1 PR, and 4 MRs. Grade 3/4 toxicities (regardless of drug attribution) were primarily hematologic, with neutropenia (40%), thrombocytopenia (23%) and anemia (4%) respectively. Grade 3/4 nonhematologic AEs included infections in 5 (1 while neutropenic), 3 diarrhea (transient), 4 fatigue & 1 pulmonary embolus and 1 pt each with: neck pain, QTc prolongation & weight loss. Patients requiring dose reductions of len/pan respectively were 4/4 for ANC, 5/1 for plts, 1/1 for febrile neutropenia & 5 len for fatigue, & 1 pan for asymptomatic T wave inversions. No doses were held or reduced for GI toxicities. Preliminary results from RNA-seq of bone marrow (BM) aspirates comparing > PR responders (R) vs < PR non responders (NR) identify 261 differentially expressed transcripts (p<0.05). Network analysis revealed "Antigen Presentation/Cell mediated immunity" as a top network function with TLR3 and MHC Class II complex as focus molecules. Immunophenotyping of the tumor microenvironment showed increased CD1c+ myeloid dendritic cells in Rs and conversely, increased CD123+ plasmacytoid dendritic cells in NRs (p<0.05). BM cytokine analysis revealed higher IL-6 and alpha-interferon levels at baseline in Rs. Interestingly, protein levels of Cereblon, Ikaros and Aiolos were not significantly different in the 2 groups. Conclusions: In rel/ref MM, the completely oral pan len dex demonstrates encouraging ORR, DOR, and PFS, even in len-ref patients with high-risk molecular findings, indicating the essential role of pan in attaining responses. In notable contrast to PANORMA 1, this regimen is well tolerated with no significant GI toxicities and primarily expected hematologic toxicities. Updated results of planned 27 pts, including correlatives, will be presented at the annual meeting. Table 1. Study Drug Doses Study Pan 20 mg po Len 25 mg po Dex 40 mg po Mateos et al Day 1,3,5,8,10,12,15,17,19 Day 1-21 Day 1-4, 9-12,17-20 Current study Day 1,3,5,15,17,19 Day 1-21 Day 1, 8, 15 Disclosures Chari: Onyx: Consultancy, Research Funding; Celgene: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding; Array BioPharma: Consultancy, Research Funding; Millenium/Takeda: Consultancy, Research Funding; Novartis: Consultancy, Research Funding. Catamero:Millennium / Takeda: Other: Lecturer; Onyx: Other: Lecturer; Celgene: Honoraria, Other: Lecturer. Verina:Celgene: Other: Lecturer. Jagannath:Celgene: Honoraria; Janssen: Honoraria; Merck: Honoraria; Novartis: Honoraria; Bristol Myers Squibb: Honoraria.
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Shah, Jatin J., Lei Feng, Elisabet E. Manasanch, Donna M. Weber, Sheeba K. Thomas, Francesco Turturro, Raymond Alexanian, et al. "Phase I/Ib Trial of the Efficacy and Safety of Combination Therapy with Lenalidomide/Bortezomib/Dexamethasone (RVD) and Panobinostat in Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma." Blood 124, no. 21 (December 6, 2014): 33. http://dx.doi.org/10.1182/blood.v124.21.33.33.
Повний текст джерелаАнотація:
Abstract Background: Induction therapy prior to consolidation with autologous stem cell transplantation (ASCT) continues to improve with the use of proteasome inhibitors and imids and combination regimens such as RVD. Bortezomib-based induction therapy has improved overall response rates (ORR) prior to transplant, which has translated to improvements in ORR and progression free survival post ASCT. However, complete remission (CR) rates with RVD remain low (10-15%) after 4 cycles of induction therapy. Panobinostat, a histone deacetylase inhibitor, in combination with bortezomib/dexamethasone, has demonstrated a significant improvement in depth of response and progression free survival in patients (pts) with relapsed myeloma as seen in PANORMA I. Preclinical data demonstrate synergy between the combination of bortezomib and panobinostat. We undertook a phase I/Ib trial in pts with newly diagnosed myeloma (NDMM) of RVD + Panobinostat to establish the safety of the combination and goal of improving the depth of response with induction therapy prior to ASCT. Methods: The primary objective was to determine the maximum tolerated dose (MTD) and safety/tolerability of RVD + panobinostat in NDMM. Secondary objectives were to determine efficacy as measured by the CR/nCR rate after 4 cycles, ORR, tolerability/toxicity, and progression free survival. Pts had to have NDMM with indication for therapy, candidates for ASCT with and had adequate organ function. Panobinostat was administered on days 1, 3, 5, 8, 10, 12; bortezomib 1.3 mg/m2 was administered subcutaneously on days 1, 4, 8, 11; lenalidomide 25 mg on days 1-14; dexamethasone 20 mg on days 1, 2, 4, 5, 8, 9, 11, and 12 on a 21 day cycle. Dose-escalation of panobinostat used a standard 3+3 schema with dose-limiting toxicities (DLTs) assessed during cycle 1. Three dose levels were studied with Panobinostat escalated from 10 to 20 mg. Adverse events (AEs) were graded by NCI-CTCAE v4, while responses were assessed by the modified International Uniform Response Criteria. Results: 22 pts were enrolled; 12 pts in the completed phase 1 dose escalation portion of the study and 10/20 in the ongoing dose expansion. The median age was 61 (range 53-79); ISS stage I 12; stage II 7/20; stage III in 3/20 pts. No DLTs were observed in 3 pts dosed in cohort 1, with Panobinostat at 10 mg. In cohort 2, panobinostat was dosed at 15 mg, 2/6 pts encountered a DLT. One patient experienced Grade 4 (G4) thrombocytopenia, and the second patient had G3 diarrhea without supportive measures, for <12 hours and resolved with supportive measures. In cohort 1, 3 additional patients were enrolled and no DLTs were encountered in the remaining 3 pts. The final recommended dose was Panobinostat 10 mg in combination with RVD in NDMM. Treatment emergent SAEs related to therapy observed in 5 pts with 2 incidences of G3 diarrhea; 2 pts with atrial fibrillation; and other events included G4 thrombocytopenia; G3 bacteremia, G3 cellulitis, G3 myocardial infarction (MI), G3 pulmonary emboli; G3 pneumonia. Hematologic adverse events G3/4 included anemia 3/22; neutropenia 4/22; thrombocytopenia 7/22. G3/4 nonhematologic toxicities included ALT elevation (n=2); AST elevation (n=1); constipation (n=2); diarrhea (n=2); fatigue/muscle weakness (n=2); MI (n=1); pneumonia (n=3). Among 18/22 pts who have completed 4 cycles of therapy and are evaluable for efficacy, the ORR (≥PR) was 100%: including nCR/CR in 5/18 (28%), VGPR in 5/18 (28%), PR in 8/18 (44%). Conclusions: MTD has been established at level 1, with panobinostat 10 mg and full dose RVD in NDMM. The DLTs were diarrhea (irrespective of supportive care) and thrombocytopenia. This is the first experience with panobinostat and subcutaneous bortezomib and first experience in combination with RVD. The combination is well tolerated with limited toxicity and side effects can be managed with supportive care. The preliminary activity after 4 cycles of therapy demonstrated a high ORR of 100% and a promising depth of response with a nCR/CR of 27%. Enrollment in a dose expansion cohort is near completion and full data will be presented at ASH. Disclosures Shah: Onyx Pharmaceuticals: Consultancy, Research Funding; Celgene: Consultancy, Research Funding; Millennium Pharmaceuticals: Consultancy, Research Funding; Novartis: Consultancy, Research Funding; Array: Consultancy, Research Funding. Off Label Use: Carfilzomib for use in front-line tx of multiple myeloma . Weber:OncPep: Research Funding. Thomas:Novartis, Celgene, Millenium, Idera Pharmaceuticals: Consultancy, Research Funding. Orlowski:Onyx Pharmaceuticals: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Millennium Pharmaceuticals: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding.
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Shah, Jatin J., Lei Feng, Elisabet E. Manasanch, Donna Weber, Sheeba K. Thomas, Francesco Turturro, Nina Shah, et al. "Phase I/II Trial of the Efficacy and Safety of Combination Therapy with Lenalidomide/Bortezomib/Dexamethasone (RVD) and Panobinostat in Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma." Blood 126, no. 23 (December 3, 2015): 187. http://dx.doi.org/10.1182/blood.v126.23.187.187.
Повний текст джерелаАнотація:
Abstract Background: Induction therapy prior to autologous stem cell transplantation (ASCT) continues to improve with the use of multi-drug combination regimens. Panobinostat (pano), a deacetylase inhibitor, was recently approved in combination with bortezomib/dexamethasone for relapsed myeloma based on the phase III PANORMA I trial for RRMM. The addition of pano in PANORAMA demonstrated a near doubling in CR rate from 15 to 27%. We previously reported phase I trial data of RVD + pano in newly diagnosed myeloma (NDMM) and demonstrated the pano can be safely combined with RVD. Based on the encouraging preliminary data we pursued a phase II dose expansion to further explore the potential improvement in depth of response with RVD + pano in NDMM. Methods: The primary objective was to determine the safety/tolerability of pano and RVD in NDMM. Secondary objectives were to determine efficacy as measured by the CR/nCR rate after 4 cycles, ORR, tolerability/toxicity, and progression free survival. Patients had to have NDMM with indication for therapy and be eligible for ASCT with adequate organ function. Panobinostat 10 mg was administered on days 1, 3, 5, 8, 10, 12; bortezomib 1.3 mg/m2 was administered subcutaneously on days 1, 4, 8, 11; lenalidomide 25 mg on days 1-14; dexamethasone 20 mg on days 1, 2, 4, 5, 8, 9, 11, and 12 on a 21 day cycle. Adverse events (AEs) were graded by NCI-CTCAE v4 and responses were assessed by the modified International Uniform Response Criteria. Results: 42 patients (pts) were enrolled; 12 in the dose escalation and 30 in the dose expansion. The median age was 60 (range 44-79); male (n=30); ISS stage I (n=28); ISS stage II (n=10); ISS stage III (n=4); 14/42 pts had high risk myeloma (1 pt with t(4:14) and del17p; 1 pt with del 17p and 1q21; and 12 pts with only 1q21 amplification). Among 42 pts, 2 completed only 1-2 cycles and 1 pt was inevaluable for response. Among the 39 pts who completed 4 cycles and were evaluable for efficacy the ORR (≥PR) after 4 cycles was 93% (36/39) including nCR/CR in 17/39 (44%), VGPR in 10/39 (26%), PR in 9/39 (23%), and SD in 3/39 (8%) pts. In 12 of 14 pts with high risk disease, who were evaluable for response, the ORR was 100% (12/12); the nCR/CR in 6/12 pts; VGPR in 4/12 pts; and 2/12 pts achieved a PR. 25/42 (59%) pts completed induction therapy and underwent consolidation with ASCT; 5 pts completed induction therapy, came off study and did not proceed to ASCT. 8 pts choose a delayed transplant approach, completed induction therapy and stem cell collection. 6 of those 8 pts remain on trial with maintenance therapy (len/dex/pano) per protocol. 2 pts, neither with high risk disease, progressed after cycles 10 and 11 with extramedullary disease and plasma cell leukemia/central nervous system involvement, respectively. 4 additional patients have completed 2, 3, and 5 cycles of therapy and are pending ASCT. Grade 3-4 hematologic adverse events included anemia (5); neutropenia (10); thrombocytopenia (16). Grade 3-4 nonhematologic toxicities included ALT elevation (1); AST elevation (1); constipation (2); diarrhea (4); dyspnea (2); fatigue/muscle weakness (5); syncope (2); MI (1); nausea (3); peripheral neuropathy (2); rash (1); DVT/VTE (3). Infectious complications included grade 2 (G2) urinary tract infection (2); G2 upper respiratory tract infection (5); pneumonia (5); osteomyelitis/musculoskeletal (3); infection (3). Treatment emergent serious adverse events related to therapy observed were: G3 pneumonia (9); G2 fever (5), G3-4 venous thromboembolic events (2); G3 diarrhea (2); atrial fibrillation (2). Other events included 1 pt each with G3 cellulitis, G3 myocardial infarction (MI), G3 febrile neutropenia, G2 diarrhea, G2 seizure, G3 hypotension and G3 sinusitis. 1 pt had a second primary malignancy - a newly diagnosed breast cancer during cycle 9 of therapy. Conclusions: Panobinostat 10 mg can be safely combined with full dose RVD in NDMM. The side effect profile with use of subcutaneous bortezomib demonstrated minimal gastrointestinal toxicity/diarrhea and was a well-tolerated combination. The combination of RVD+ pano lead to rapid disease control with high response rate after 4 cycles of therapy and ORR of 93% and significant depth of response with a 4 cycle nCR/CR rate of 44%. Enrollment in dose expansion is near completion and full data will be presented at ASH and supports the study of panobinostat in a randomized trial for NDMM. Disclosures Shah: Celgene: Consultancy, Research Funding. Thomas:Celgene: Research Funding; Novartis: Research Funding; Idera Pharmaceuticals: Research Funding. Orlowski:Genentech: Consultancy; Acetylon: Membership on an entity's Board of Directors or advisory committees; Bristol-Myers Squibb: Consultancy, Research Funding; Spectrum Pharmaceuticals: Research Funding; Celgene: Consultancy, Research Funding; Array BioPharma: Consultancy, Research Funding; Janssen Pharmaceuticals: Membership on an entity's Board of Directors or advisory committees; Onyx Pharmaceuticals: Consultancy, Research Funding; BioTheryX, Inc.: Membership on an entity's Board of Directors or advisory committees; Millennium Pharmaceuticals: Consultancy, Research Funding; Forma Therapeutics: Consultancy.
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Gaál, Balázs. "Antonio Cassarino's Latin translation of Plutarch's Bruta animalia ratione uti." Acta Antiqua Academiae Scientiarum Hungaricae, August 30, 2022. http://dx.doi.org/10.1556/068.2022.00014.
Повний текст джерелаАнотація:
Abstract The present paper aims at giving a text edition of Antonio Cassarino's humanist Latin translation of Plutarch's dialogue Bruta animalia ratione uti. This is the earliest of three translations made of this dialogue in the course of the 15th century. The text itself is extant in three different manuscripts, one of which is a codex of the Vatican Library (Vat. lat. 3349), compiled after Cassarino's death by Panormita. A comparison of the text variants has led to several results. First, some of the errors shared by all three manuscripts show that they go back to a common archetype already at some distance from the translator's original copy. Second, Panormita relied heavily on a codex of the Biblioteca della Società Siciliana per la Storia Patria in Palermo (MS Lodi XII E 13) in preparing his own version. Third, the Vatican codex is far from being the best representative of Cassarino's original translation. Though Panormita corrected several of the common inherited errors, he made changes to the text without consulting the Greek. In almost every instance, it is a codex of the Biblioteca Casanatense of Rome (Bibl. Casan. 665 C II 8) which gives the best reading, providing the clue for a successful reconstruction of the text. An attempt will be made to trace the version contained in this codex back to a certain person named Balbi, referred to in the dedicatory letter as being a learned expert of both languages, Greek and Latin. Along with the establishment of the text, it will also be possible to define the original Greek source codex Cassarino used for his translation (Vat. Pal. gr. 170).
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Sedano, Joaquín. "IV. A Comparative Analysis of the Panormia and the Collectio X Partium." Zeitschrift der Savigny-Stiftung für Rechtsgeschichte. Kanonistische Abteilung 96, no. 1 (January 1, 2010). http://dx.doi.org/10.7767/zrgka.2010.96.1.80.
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Leisching, Peter. "Consuetudo und ratio im Dekret und der Panormia des Bischofs Ivo von Chartres." Zeitschrift der Savigny-Stiftung für Rechtsgeschichte. Kanonistische Abteilung 74, no. 1 (January 1, 1988). http://dx.doi.org/10.7767/zrgka.1988.74.1.535.
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Basilone, Luca. "Sequence stratigraphy of a Mesozoic carbonate platform-to-basin system in western Sicily." Open Geosciences 1, no. 3 (January 1, 2009). http://dx.doi.org/10.2478/v10085-009-0021-8.
Повний текст джерелаАнотація:
AbstractSequence stratigraphic studies of the Triassic through Paleogene carbonate successions of platform, slope and basin in western Sicily (Palermo and Termini Imerese Mountains) have identified a sedimentary cyclicity mostly caused by relative oscillations of sea level. The stratigraphic successions of the Imerese and Panormide palaeogeographic domains of the southern Tethyan continental margin were studied with physical-stratigraphy and facies analysis to reconstruct the sedimentary evolution of this platform-to-basin system.The Imerese Basin is characterized by a carbonate and siliceous-calcareous succession, 1200–1400m thick, Late Triassic to Eocene in age. The strata display a typical example of a carbonate platform margin, characterized by resedimented facies with progradational stacking patterns. The Panormide Carbonate Platform is characterized by a carbonate succession, 1000–1200 m thick, Late Triassic to Late Eocene, mostly consisting of shallow-water facies with periodic subaerial exposure.The cyclic arrangement has been obtained by the study of the stratigraphic signatures (unconformities, facies sequences, erosional surfaces and stratal geometries) found in the slope successions. The recognized pattern has been compared with coeval facies of the shelf. This correlation provided evidence of sedimentary evolution, influenced by progradation and backstepping of the shelf deposits.The stratigraphic architecture of the platform-to-basin system is characterized by four major transgressive/regressive cycles during the late Triassic to late Eocene.These cycles, framed in a chronostratigraphic chart, allows the correlation of the investigated shelf-to-basin system with the geological evolution of the African continental margin during the Mesozoic, showing tectono-eustatic cycles. The first cycle, encompassing the late Triassic to early Jurassic, appears to be related to the late syn-rift stage of the continental margin evolution. The following three cycles, spanning from the Jurassic to Eocene, can be related to the post-rift evolution and to thermal subsidence changes.
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Randazzo, V., S. Todaro, S. Provenzale, V. Di Dio, and P. Di Stefano. "Geoconservation in Sicily (Italy): the Example of the Isola delle Femmine (Palermo)." Geoheritage 14, no. 2 (May 20, 2022). http://dx.doi.org/10.1007/s12371-022-00704-w.
Повний текст джерелаАнотація:
Abstract The Regional Administration of Sicily recently erected Isola delle Femmine—a small island of the Tyrrhenian Sea, close to Palermo—as a geosite. A detailed geological survey has been carried out in order to define the most important geological features of the island together with the development of a new geological map based on topographic data and a digital model at 1:2.000 scale specially processed. Finally, a geological pathway through the island has been traced and illustrated. The geological substrate of Isola delle Femmine consists of a Mesozoic carbonate succession belonging to the Panormide Carbonate Platform. Two lithostratigraphic units have been differentiated. The lowest one consists of dolomitic limestones cropping out in the intermediate and northern part of the island. Despite the absence of biostratigraphic constrains, analogies with comparable deposits from the Palermo Mountains suggested to ascribe this unit to the Upper Triassic. The overlying unit consists of well-bedded rudist and stromatolitic limestones organized in peritidal cycles. The macro- and micro-facies analysis of these Cretaceous limestones allows to attribute this unit to the Lower Cretaceous (i.e., Aptian). Patches of upper Pleistocene skeletal calcarenites rich in benthic foraminifers and calcareous algae overlap the Mesozoic units. Spectacular speleothems such as stalagmites, ray crystals (“raggioni”) of calcite, and mammillary calcite suggest a relative long-lasting exposure of the Mesozoic carbonate substrate to groundwater. This is not surprising since glacio-eustatic oscillations caused sea-level to fall up to 125 m during the Pleistocene thus exposing and linking to the mainland (Sicily) Isola delle Femmine and the surrounding area.