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1

Murdayanti, Maulida, Jabal Tarik Ibrahim, and Istis Baroh. "Farmer Empowerment Strategies Through Organic Vegetables Development." SOCA: Jurnal Sosial, Ekonomi Pertanian 15, no. 1 (January 30, 2021): 108. http://dx.doi.org/10.24843/soca.2021.v15.i01.p10.

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Organic vegetable cultivation system is a system for growing vegetables that is safe for consumption. The aims of this study were to conduct external and internal analysis of Mulyo Santoso Farmers Group Association using SWOT analysis, to find out effective strategies in empowering farmers through vegetable development, and to compile strategies for empowering farmers through organic vegetable development by Mulyo Santoso Farmers Group Association. This study is a descriptive study using quantitative descriptive approach. The data used were primary data obtained through interviews using questionnaires. This research used SWOT analysis method. The sampling technique used was census, using all members of the population as samples. Internal factor analysis results show the acquisition of a strength indicator score of 1.53 and a weak indicator score of 1.04. The results of the analysis on external factors acquisition show the opportunity indicator score of 1.32 and the threat indicator score of 1.20. The resulting value of SWOT diagram analysis on the X axis for internal factors is 0.49 and Y axis on external factors is 0.12. Based on the results of the SWOT analysis, it is known that the strategy used by Mulyo Santoso Farmers Group Association is an aggressive or progressive strategy, by using the power to take advantage of opportunities by creating, producing and developing businesses of processed agricultural products, such as processed chips and catering services of healthy foods, as well as adding more varieties of cultivated vegetables and sell organic fertilizer to supplement the income
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2

Leksono, Amin Setyo, Irfan Mustafa, Zulfaidah Penata Gama, Aminudin Afandhi, and Anisa Zairina. "Organic cocoa farming in Indonesia: constraints and development strategies." Organic Agriculture 11, no. 3 (April 2, 2021): 445–55. http://dx.doi.org/10.1007/s13165-021-00351-5.

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3

Dos Santos, Alcindo A. "Applied organic synthesis in action: strategies and process development." Tetrahedron 70, no. 20 (May 2014): 3230. http://dx.doi.org/10.1016/j.tet.2014.02.053.

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4

Lambert, Tristan H. "Development of a Hydrazine-Catalyzed Carbonyl-Olefin Metathesis Reaction." Synlett 30, no. 17 (June 5, 2019): 1954–65. http://dx.doi.org/10.1055/s-0039-1689924.

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Анотація:
Carbonyl-olefin metathesis is a potentially powerful yet underexplored reaction in organic synthesis. In recent years, however, this situation has begun to change, most notably with the introduction of several different catalytic technologies. The development of one of those new strategies, based on hydrazine catalysts and a novel [3+2] paradigm for double bond metathesis, is discussed herein. First, the stage is set with a description of some potential applications of carbonyl-olefin metathesis and a discussion of alternative strategies for this intriguing reaction.1 Introduction2 Potential Applications of Carbonyl-Olefin Metathesis3 Carbonyl-Olefin Metathesis Strategies4 Direct (Type I): Non-Catalytic5 Direct (Type I): Acid-Catalyzed6 Indirect (Type II): Metal Alkylidenes7 Indirect (Type III): Hydrazine-Catalyzed8 Conclusion
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5

Lähdesmäki, Merja, Marjo Siltaoja, Harri Luomala, Petteri Puska, and Sami Kurki. "Empowered by stigma? Pioneer organic farmers’ stigma management strategies." Journal of Rural Studies 65 (January 2019): 152–60. http://dx.doi.org/10.1016/j.jrurstud.2018.10.008.

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6

WÜLFERT, Ernst. "TREATMENT DEVELOPMENT STRATEGIES FOR ALZHEIMER'S DISEASE." European Journal of Medicinal Chemistry 30 (1995): 147s—162s. http://dx.doi.org/10.1016/s0223-5234(23)00121-6.

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7

Kunz, S., A. Schmitt, and P. Haug. "DEVELOPMENT OF STRATEGIES FOR FIRE BLIGHT CONTROL IN ORGANIC FRUIT GROWING." Acta Horticulturae, no. 896 (May 2011): 431–36. http://dx.doi.org/10.17660/actahortic.2011.896.62.

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8

LARINA, YAROSLAVA, VIRA FOMISHYNA, and OLENA SHAPORENKO. "MARKETING STRATEGIES FOR PROMOTION OF ORGANIC FOODSTUFFS ON FOREIGN MARKETS." Economic innovations 23, no. 3(80) (August 20, 2021): 195–204. http://dx.doi.org/10.31520/ei.2021.23.3(80).195-204.

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Анотація:
Topicality. Marketing becomes a necessary and effective tool for doing business, the basis of enterprise management, which is strategically focused on achieving market success. However, domestic companies - participants in the market of organic products have not yet fully realized the need to implement modern principles and tools of marketing. Special attention needs to be paid to the strategic aspects of the operation of such enterprises, in particular, the development of marketing strategies for promotion in domestic and foreign markets. Commercial and communication effects will depend on the correct choice of basic, foreign economic, competitive and functional strategies, promotion channels, formation of communication appeal, amount of invested funds, etc. Aim and tasks. The purpose of the article is to develop theoretical and methodological foundations for the formation and implementation of strategies for promoting organic food products in foreign markets, taking into account changes in consumer needs and demand dynamics. The objectives of the study include: identifying key trends in the consumption of organic products on the world market; clarification of the stages of formation of the marketing strategy of promotion of organic food products on foreign markets. Research results. The results of the research give grounds to claim that insufficient dynamics of growth of the domestic market of organic products transforms foreign economic activity into the main component of effective development of producers of organic food products. It is proved that the largest consumers of organic food are countries with a high level of socio-economic development and a high standard of living of the majority of the population. The following regularities of development of foreign markets of organic products are revealed: expansion of the range of organic products, steady tendency of growth of sales volumes, supported by import; high quality requirements, mandatory certification. The main markets for organic products are European markets, China, Canada, USA, Latin America. It was found that in foreign markets the most important problems in the field of promotion are the complexity of studying the marketing environment, identifying key characteristics of the target consumer and compliance with standards in a particular country. Conclusion. Based on the study, conclusions about the following stages formation of marketing strategy of advancement of organic foodstuff on foreign markets were made: defining the goals of promotion; assessment of factors influencing the strategy and complex of promotion; the actual development of the strategy; the choice of means of influencing consumers; budget calculation. The most important factors for the formation of marketing strategy to promote organic food products to foreign markets and ensure high performance of companies exporting organic products are: determining the type of buyer, target audience, product type, stage of the life cycle. It has been proven that in the process of bringing organic food products to the foreign market, it is advisable to apply a push strategy at the beginning, as intermediaries better understand the specifics of demand and local consumers. and in the future for the development of the market you can also use the strategy of attraction or mixed.
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9

Predygier, Agnieszka. "ANALYSIS AND ASSESSMENT OF DEVELOPMENT STRATEGIES OF SELECTED ŚWIĘTOKRZYSKIE CLUSTERS." Zeszyty Naukowe Wyższej Szkoły Humanitas Zarządzanie 21, no. 3 (September 30, 2020): 41–54. http://dx.doi.org/10.5604/01.3001.0014.4507.

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Анотація:
Strategies for increasing the competitiveness of entities are created by building multilevel inter-organizational relations. These ties take on the character of clusters or clusters. Entities seek new competitive opportunities in a global cooperation network and take advantage of location advantages. Integrating into clusters creates new competitive opportunities, innovative opportunities and eliminates location defects. Scenarios for the development of clusters together with the determinants of the competitive success of entities will be described in the organic concept of cluster creation. In favorable conditions, clusters can transform into strands or multigrons. The bands eliminate or limit location defects of entities and open competitive opportunities on the global market. The organic concept of creating grapes was observed on the competitive success of the Świętokrzysko-Podkarpackie Construction Cluster INNOWATOR and Grona Targowe Kielce. Competitive chances of entities operating in clusters have been subject to questionnaire surveys, the results of which will be presented in subsequent articles.
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10

Budiani, Ni Putu Ariesta, Ni Luh Suastuti, and Lidjah Magdalena Massenga. "MARKETING STRATEGIES FOR ORGANIC RESTAURANT IN UBUD TOURIST AREA - BALI." Journal of Business on Hospitality and Tourism 2, no. 1 (January 6, 2017): 393. http://dx.doi.org/10.22334/jbhost.v2i1.74.

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Анотація:
Public awareness of the importance of adopting a healthy lifestyle continues to increase. One indicator can be seen is an increase in the consumption of organic food. Likewise, the high interest of the global community in organic food is expected to impact on the restaurant business in Bali, especially in Ubud Tourist Area. At this time there are some marketing difficulties facing the restaurant business that sells food made from organic. The purpose of research is exploring the strengths, weaknesses, opportunities, and threats organic restaurant in Ubud Tourist Area - Bali. It is also to investigate the marketing strategy to increase tourists visiting an organic restaurant in Region Ubud - Bali.Methods of data collection using observation, interviews, questionnaires, and documentation, and then analyzed using SWOT analysis. The results of this study are the internal condition of organic restaurants in Ubud Tourist Area is excellent for tourists and managers of restaurants, as well as external environmental conditions in Ubud. Based on a combination of analysis and IE Matrix Matrix position, the right strategy is applied industry Organic restaurant in Ubud Tourist Area is a strategy of market penetration, product development, and market development is limited.
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11

Fok, Jelle A., and Clemens Mayer. "Genetic‐Code‐Expansion Strategies for Vaccine Development." ChemBioChem 21, no. 23 (July 30, 2020): 3291–300. http://dx.doi.org/10.1002/cbic.202000343.

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12

Handayani, Sri, Irmayani Noer, and Rini Desfaryani. "Development Strategy of Organic Rice in Lampung Selatan Regency." IOP Conference Series: Earth and Environmental Science 1012, no. 1 (April 1, 2022): 012030. http://dx.doi.org/10.1088/1755-1315/1012/1/012030.

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Abstract Abstract As one of the commodities supporting food security is underdeveloped due to marketing problems. Fluctuating supply and prices of organic rice, weak market information, high transportation costs, organic product certification, and limited capital become the basis for the need for analysis strategy for developing an organic rice market. The purpose of this study are: (1) identify the internal and external environmental factors, (2) formulate the best alternative strategy for the development of the organic rice market in South Lampung Regency. The research was carried out in Candipuro sub-district, based on being a center for organic rice production in South Lampung Regency. The data were analyzed qualitative and quantitative using descriptive analysis, identification of Strengths, Weaknesses, Opportunities, and Threats using IFE and EFE matrices, to obtain alternative strategies using the IE matrix and SWOT matrix. The results of the analysis show that the main weakness of the organic rice farmer group is the low performance of human resources and the limited number and types of organic products that cause a lack of market share for organic rice. The result of the IE matrix shows that the Mitra Organic Farmer Group is in the position Diversification. This policy needs to be implemented in preparation for broad diversification into various types of business activities that provide opportunities for improving the role of an institution or institution (conglomerate diversification strategy). Alternative strategies formulated based on the SWOT matrix are (1) increasing the number and types of organic products produced/product diversification, and (2) increasing institutional capacity to become cooperatives to optimize the government’s role in market accessibility and funding.
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13

Cezar, Everson, Marcos Rafael Nanni, Luís Guilherme Teixeira Crusiol, Liang Sun, Mônica Sacioto Chicati, Renato Herrig Furlanetto, Marlon Rodrigues, et al. "Strategies for the Development of Spectral Models for Soil Organic Matter Estimation." Remote Sensing 13, no. 7 (April 2, 2021): 1376. http://dx.doi.org/10.3390/rs13071376.

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Анотація:
Visible (V), Near Infrared (NIR) and Short Waves Infrared (SWIR) spectroscopy has been indicated as a promising tool in soil studies, especially in the last decade. However, in order to apply this method, it is necessary to develop prediction models with the capacity to capture the intrinsic differences between agricultural areas and incorporate them in the modeling process. High quality estimates are generally obtained when these models are applied to soil samples displaying characteristics similar to the samples used in their construction. However, low quality predictions are noted when applied to samples from new areas presenting different characteristics. One way to solve this problem is by recalibrating the models using selected samples from the area of interest. Based on this premise, the aim of this study was to use the spiking technique and spiking associated with hybridization to expand prediction models and estimate organic matter content in a target area undergoing different uses and management. A total of 425 soil samples were used for the generation of the state model, as well as 200 samples from a target area to select the subsets (10 samples) used for model recalibration. The spectral readings of the samples were obtained in the laboratory using the ASD FieldSpec 3 Jr. Sensor from 350 to 2500 nm. The spectral curves of the samples were then associated to the soil attributes by means of a partial least squares regression (PLSR). The state model obtained better results when recalibrated with samples selected through a cluster analysis. The use of hybrid spectral curves did not generate significant improvements, presenting estimates, in most cases, lower than the state model applied without recalibration. The use of the isolated spiking technique was more effective in comparison with the spiked and hybridized state models, reaching r2, square root of mean prediction error (RMSEP) and ratio of performance to deviation (RPD) values of 0.43, 4.4 g dm−3, and 1.36, respectively.
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14

Rengkung, Riana ,., Martha Mareyke Sendow, and Agnes Estephina Loho. "STRATEGI PENGEMBANGAN PADI ORGANIK DI KABUPATEN MINAHASA TENGGARA (DEVELOPMENT STRATEGIES OF ORGANIC RICE IN SOUTHEAST MINAHASA DISTRICT." AGRI-SOSIOEKONOMI 17, no. 1 (January 15, 2021): 21. http://dx.doi.org/10.35791/agrsosek.17.1.2021.32237.

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Анотація:
The purpose of this study is to formulate the right strategy to develop organic rice in Molompar Dua Utara Village. This study was conducted in November 2019 to March 2020. The data collection method used was a survey method. The data used in this study was primary dan secondary data. The primary data were obtained through direct interview with 11 respondents using a questionnaire, and the secondary data was obtained from the Agriculture Department of Southeast Minahasa Regency. The result of this study shows the right strategy for the development of Agrobiz Mitra’s organic rice is growth oriented strategy, including: maintaining product certification through the use of quality organic seeds and fertilizers, avoiding products from chemical contamination to maintain consumer safety. Furthermore, expanding the marketing network by holding special markets, collaborating with the Government in setting prices for organic farming products, expanding bussiness by improving brand awareness to expand marketing network. On the other hand, experienced farmer engage in the socialization of organic rice farming.
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15

Morgan, Alan R. "Strategies for the Development of Photodynamic Sensitizers." Current Medicinal Chemistry 2, no. 2 (August 1995): 604–15. http://dx.doi.org/10.2174/0929867302666220217235922.

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Abstract: The use of light activated dyes in photomedicine offers the potential to administer to patients an inert compound which can be selectively activated by photoirradiation. Such a process allows for unique control of the photochemotherapeutic process, using techniques to enhance drug targeting and/or selective irradiation of target tissues. Substantial progress has been made iri recent years in developing biologically compatible photosensitizers and in understanding their mechanisms of action. In one field of photcimedicine called Photodynamic Therapy, excitation of the sensitizer leads to the generation of activated oxygen species which then oxidize biological .substrates such as protein and lipids. Since different sensitizers localize in different cell types and in differe-nt subcellular organelles, the mechanisms of cell necrosis may differ. Current research is aimed at better understanding the parameters responsible for these properties of photosensitizers and in expanding the disease indications to which phototherapy can be applied.
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16

Voronkova, O., and O. Vysotskaya. "Implementing the organic farming concept in strategies of sustainable development: European and Russian perspectives." Ukrainian Journal of Ecology 9, no. 3 (September 26, 2019): 421–24. http://dx.doi.org/10.15421/2019_120.

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Анотація:
The tradition of organic agriculture is at present increasingly strengthening its position in European countries and becoming a paradigm for building up sustainable development strategies, ecological and economic security of regions. A more ecological model becomes a necessity today. It offers a great opportunity for European producers of organic products to get a long-term sustainability and competitive advantages. The world economic crisis has further influenced and forced the interest of producers and consumers in high-quality and safe products. The article considers approaches to implementing the organic farming concept as part of building up strategies of sustainable development of EU regions in comparison with the Russian Federation, analyzes the main state mechanisms of this process.
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17

Manabe, Yoshiyuki, Atushi Shimoyama, Kazuya Kabayama, and Koichi Fukase. "Middle Molecular and Conjugation Strategies for Development of Bioactive Middle Molecules." Journal of Synthetic Organic Chemistry, Japan 78, no. 5 (May 1, 2020): 527–37. http://dx.doi.org/10.5059/yukigoseikyokaishi.78.527.

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18

KOVALCHUK, Svitlana. "ORGANIC PRODUCTION IN THE SYSTEM OF SUSTAINABLE DEVELOPMENT OF RURAL AREAS." "EСONOMY. FINANСES. MANAGEMENT: Topical issues of science and practical activity", no. 4 (54) (December 19, 2020): 117–33. http://dx.doi.org/10.37128/2411-4413-2020-4-8.

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Анотація:
Climate problems, the state of the environment, the Covid-19 crisis are the main problems of today that directly affect agricultural production and as a consequence the sustainable development of rural areas. The article analyzes the factors of reorientation of agricultural production to organic production. Emphasis is placed on preserving local agricultural traditions and scientifically sound approaches to organic production to ensure sustainable development of rural areas. Using Forsight research, the relationship between balanced rural development and organic production is predicted. The basic strategies of competition have been identified with the help of the five Porter forces, in order to develop a strategy for successful entry into organic markets and maintaining supply chains during the Covid-19 period. Emphasis is placed on high requirements for agricultural products and compliance with environmental standards in their production, which may be an obstacle to further exports of Ukrainian organic products to the EU market. The relationship between the dynamics of organic production and a set of measures and determinants that determine the natural resources and production and technical conditions of rural development is substantiated using the SMART-method. It is argued that organic production is a resource basis for the development of strategies to increase the production of agricultural products, finished food products and sustainable development of rural areas. The importance of organic production during the COVID-19 crisis is outlined. It is proved that there is practically no alternative to the development of agriculture under the organic scenario in the system of sustainable development of rural areas in the long run.
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19

Elliott, Scott, Nicole Jeffery, Elizabeth Hunke, Clara Deal, Meibing Jin, Shanlin Wang, Emma Elliott Smith, and Samantha Oestreicher. "Strategies for the Simulation of Sea Ice Organic Chemistry: Arctic Tests and Development." Geosciences 7, no. 3 (July 14, 2017): 52. http://dx.doi.org/10.3390/geosciences7030052.

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20

Rauws, Ward, and Gert De Roo. "Adaptive planning: Generating conditions for urban adaptability. Lessons from Dutch organic development strategies." Environment and Planning B: Planning and Design 43, no. 6 (July 27, 2016): 1052–74. http://dx.doi.org/10.1177/0265813516658886.

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21

Wang, Yujing, Qi Gong, and Qian Miao. "Structured and functionalized organic semiconductors for chemical and biological sensors based on organic field effect transistors." Materials Chemistry Frontiers 4, no. 12 (2020): 3505–20. http://dx.doi.org/10.1039/d0qm00202j.

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Анотація:
This review gives an overview of strategies to tailor organic semiconductors with designed physical structures and chemical functionalities for development of chemical and biological sensors based on organic field effect transistors.
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22

Rodríguez-Mayor, Andrea Verónica, German Jesid Peralta-Camacho, Karen Johanna Cárdenas-Martínez, and Javier Eduardo García-Castañeda. "Development of Strategies for Glycopeptide Synthesis: An Overview on the Glycosidic Linkage." Current Organic Chemistry 24, no. 21 (December 7, 2020): 2475–97. http://dx.doi.org/10.2174/1385272824999200701121037.

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Анотація:
Glycoproteins and glycopeptides are an interesting focus of research, because of their potential use as therapeutic agents, since they are related to carbohydrate-carbohydrate, carbohydrate-protein, and carbohydrate-lipid interactions, which are commonly involved in biological processes. It has been established that natural glycoconjugates could be an important source of templates for the design and development of molecules with therapeutic applications. However, isolating large quantities of glycoconjugates from biological sources with the required purity is extremely complex, because these molecules are found in heterogeneous environments and in very low concentrations. As an alternative to solving this problem, the chemical synthesis of glycoconjugates has been developed. In this context, several methods for the synthesis of glycopeptides in solution and/or solid-phase have been reported. In most of these methods, glycosylated amino acid derivatives are used as building blocks for both solution and solid-phase synthesis. The synthetic viability of glycoconjugates is a critical parameter for allowing their use as drugs to mitigate the impact of microbial resistance and/or cancer. However, the chemical synthesis of glycoconjugates is a challenge, because these molecules possess multiple reaction sites and have a very specific stereochemistry. Therefore, it is necessary to design and implement synthetic routes, which may involve various protection schemes but can be stereoselective, environmentally friendly, and high-yielding. This review focuses on glycopeptide synthesis by recapitulating the progress made over the last 15 years.
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23

Yu, Zhi Chun, and Zhen Lin Lei. "The Ecological Strategies on Development of Rural Communities in Northwest China." Applied Mechanics and Materials 641-642 (September 2014): 598–602. http://dx.doi.org/10.4028/www.scientific.net/amm.641-642.598.

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Анотація:
Nowadays faced with opportunities and challenges under a rapid urbanization, it is severe existing situations of rural area in Northwest China. From the village planning to its house construction, we need to follow the ecological and sustainable way, emphasize the application on ecology in architecture, inherit and revolution local history and culture, pass on the indigenous eco-experience and utilize the modern techniques to solve the organic replenishment of the traditional dwelling. To establishing the ecological rural community in Northwest China, that is our goals, push the ecological process of Northwest country forward.
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24

Antczak, Elżbieta. "Analyzing Spatiotemporal Development of Organic Farming in Poland." Sustainability 13, no. 18 (September 17, 2021): 10399. http://dx.doi.org/10.3390/su131810399.

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Анотація:
Organic farming is one of the most widely known sustainable models of agricultural production. Success in eco-agriculture also depends greatly on agri-environmental, territorial, economic, social, institutional and spatial conditions. Polish eco-farming is very regionally dispersed and diversified. Regarding the important contribution of organic farming, a better understanding of how this phenomenon develops and which factors affect its spatial distribution can be influential for policymakers in planning strategies that pursue sustainable development objectives in rural areas. This paper assesses the development and analyses the spatial distribution of organic farming in Polish LAU-2. The country’s eco-agriculture was mapped and defined using a synthetic measure, described by 27 sub-measurements of ecological crop cultivation, animal maintenance and eco-production. The local spatial patterns (direction, scale, and range) of organic farming were detected by spatial autocorrelation measurements. The analysis was conducted for the period 2014–2020. Possible external and internal determinants of this spatial dispersion were also defined. The results indicate that the distribution and spread of organic farming in Poland are related to public support, institutional regulations, social considerations, environmental concerns, the local job market and spatial dependencies.
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25

Biradha, Kumar, Anindita Goswami, Rajib Moi, and Subhajit Saha. "Metal–organic frameworks as proton conductors: strategies for improved proton conductivity." Dalton Transactions 50, no. 31 (2021): 10655–73. http://dx.doi.org/10.1039/d1dt01116b.

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Анотація:
Various innovative strategies and methodologies for the development of MOFs and coordination polymers based materials for high performance solid state proton conductors and proton exchange membranes are outlined.
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26

Titisari, Manik Ayu, Denis Fidita Karya, and Surjo Hadi. "SWOT Analysis and ANP for Organic Tempeh SME Business Development Strategy." IJEBD (International Journal of Entrepreneurship and Business Development) 4, no. 6 (November 30, 2021): 913–23. http://dx.doi.org/10.29138/ijebd.v4i6.1540.

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Анотація:
Purpose: Therefore, in this study, SWOT analysis is used to formulate problems from internal and external factors, from developing alternative strategies, selecting and making strategic decisions that align with company goals. Design/methodology/approach: At the same time, the Analytical Network Process (ANP) is used to weigh each alternative strategy so that the strategy with the highest priority weight can be identified. By using Super Decision software, the best alternative strategy for Soya Agung is to promote promotion and education with a weight of 0.214760. Findings: An industry that can compete in the modern market has the right marketing strategy. As a Small and Medium Enterprise producing tempeh, whose raw material is non-genetic modified local soybeans, Soya Agung still has limitations in marketing its products. Research limitations/implications: The integration of SWOT and ANP is expected to produce strategic plans that can provide various alternative marketing strategies that can help solve company problems. Paper type: Research paper
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27

Yuhui, Xu, Liang Chengcheng, and Wu Yue. "Renewal Strategies for Communities Based on the Traffic Micro-Circulation System." Open House International 40, no. 4 (December 1, 2015): 81–87. http://dx.doi.org/10.1108/ohi-04-2015-b0013.

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Анотація:
To solve several “inorganic” problems generated recently by community development in China (e.g., waste of social resources, environmental pollution, and decreased economic energy efficiency), focus should be on improving the community traffic organic micro-circulation system. As a historic and mixed functional urban community, the micro-circulation system of Xi'an Railway Bureau exhibits representativeness and complexity. Based on existing research results and years of follow-up investigations, which concentrate on circulation patterns and inherent organic development requirements of the community traffic micro-circulation system, this paper builds an evaluation index system. Value function method was used to implement the index factor quantitative analysis and comprehensive evaluation. Several related strategies were proposed to improve the organic micro-circulation system of the community, which is based on the analysis of the evaluation, in order to adopt the trend in both increasing urban development and stock updating. The analysis results demonstrate that it is necessary to present guiding renewal strategies on community land, road, people, and the environment for those mixed functional communities which use progressive renewed mode. It compensates the problems of overly strong export-oriented system, which is caused by the lack of organic traffic micro-circulation, so as to achieve the selective opening of community external. The study mainly highlights the significance of the systematic analysis of evaluation in influencing strategies on community renewal.
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28

Kim, Mijin, Jim McCaan, Chen Chen, Ewelina Randall, Ronald Koder, and Daniel Heller. "Development of Organic Color Center Based Nanosensors for Proinflammatory Cytokine Detection." ECS Meeting Abstracts MA2022-01, no. 8 (July 7, 2022): 690. http://dx.doi.org/10.1149/ma2022-018690mtgabs.

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Organic color centers, also known as fluorescent sp3 quantum defects, on single walled carbon nanotubes, have opened exciting opportunities to re-engineer the optical and electronic properties of carbon nanotubes via covalent surface chemistry. Organic color centers produce molecularly tunable fluorescence in the near-infrared, conferring new chemical and optical functionalities that are suitable for biosensing applications. In this talk, we discuss the strategies that enhance the physical stability and optical response of the nanosensors for robust, transient detection of proinflammatory cytokines in biofluids. The sensor technology incorporates functional organic color centers augmented by biodesigned supercharged molecular recognition proteins.
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29

Feng, Liang, Kun-Yu Wang, Xiu-Liang Lv, Tian-Hao Yan, and Hong-Cai Zhou. "Hierarchically porous metal–organic frameworks: synthetic strategies and applications." National Science Review 7, no. 11 (November 5, 2019): 1743–58. http://dx.doi.org/10.1093/nsr/nwz170.

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Abstract Despite numerous advantages, applications of conventional microporous metal–organic frameworks (MOFs) are hampered by their limited pore sizes, such as in heterogeneous catalysis and guest delivery, which usually involve large molecules. Construction of hierarchically porous MOFs (HP-MOFs) is vital to achieve the controllable augmentation of MOF pore size to mesopores or even macropores, which can enhance the diffusion kinetics of guests and improve the storage capacity. This review article focuses on recent advances in the methodology of HP-MOF synthesis, covering preparation of HP-MOFs with intrinsic hierarchical pores, and modulated, templated and template-free synthetic strategies for HP-MOFs. The key factors which affect the formation of HP-MOF architectures are summarized and discussed, followed by a brief review of their applications in heterogeneous catalysis and guest encapsulation. Overall, this review presents a roadmap that will guide the future design and development of HP-MOF materials with molecular precision and mesoscopic complexity.
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30

Kuryłowicz, Alina, and Krzysztof Koźniewski. "Anti-Inflammatory Strategies Targeting Metaflammation in Type 2 Diabetes." Molecules 25, no. 9 (May 9, 2020): 2224. http://dx.doi.org/10.3390/molecules25092224.

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One of the concepts explaining the coincidence of obesity and type 2 diabetes (T2D) is the metaflammation theory. This chronic, low-grade inflammatory state originating from metabolic cells in response to excess nutrients, contributes to the development of T2D by increasing insulin resistance in peripheral tissues (mainly in the liver, muscles, and adipose tissue) and by targeting pancreatic islets and in this way impairing insulin secretion. Given the role of this not related to infection inflammation in the development of both: insulin resistance and insulitis, anti-inflammatory strategies could be helpful not only to control T2D symptoms but also to treat its causes. This review presents current concepts regarding the role of metaflammation in the development of T2D in obese individuals as well as data concerning possible application of different anti-inflammatory strategies (including lifestyle interventions, the extra-glycemic potential of classical antidiabetic compounds, nonsteroidal anti-inflammatory drugs, immunomodulatory therapies, and bariatric surgery) in the management of T2D.
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31

Thomas, Stephen P., and Jingying Peng. "Activation Strategies for Earth-Abundant Metal Catalysis." Synlett 31, no. 12 (April 6, 2020): 1140–46. http://dx.doi.org/10.1055/s-0039-1690873.

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The use of earth-abundant metal-catalysed organic transformations has increased significantly in recent years. Where low-oxidation-state catalysts are required, the in situ activation of metal(II/III) salts offers an operationally simple method to access these catalysts. Here we present the development of activation strategies from the use of reducing organometallic reagents to endogenous activation. Applications in alkene and alkyne hydrofunctionalisation reactions will be used to highlight the synthetic applications of the activation methods discussed.1 Introduction2 In situ Activation Using Organometallic Reagents3 In situ Activation Using Nonorganometallic Reagents4 ‘Activator-Free’ Systems5 Conclusions
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32

Gao, Xike, and Yunbin Hu. "Development of n-type organic semiconductors for thin film transistors: a viewpoint of molecular design." J. Mater. Chem. C 2, no. 17 (2014): 3099–117. http://dx.doi.org/10.1039/c3tc32046d.

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33

Diamantoglou, M., and J. Vienken. "Strategies for the development of haemocompatible dialysis membranes." Macromolecular Symposia 103, no. 1 (January 1996): 31–42. http://dx.doi.org/10.1002/masy.19961030106.

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34

Fenoy, Gonzalo E., Omar Azzaroni, Wolfgang Knoll, and Waldemar A. Marmisollé. "Functionalization Strategies of PEDOT and PEDOT:PSS Films for Organic Bioelectronics Applications." Chemosensors 9, no. 8 (August 6, 2021): 212. http://dx.doi.org/10.3390/chemosensors9080212.

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Organic bioelectronics involves the connection of organic semiconductors with living organisms, organs, tissues, cells, membranes, proteins, and even small molecules. In recent years, this field has received great interest due to the development of all kinds of devices architectures, enabling the detection of several relevant biomarkers, the stimulation and sensing of cells and tissues, and the recording of electrophysiological signals, among others. In this review, we discuss recent functionalization approaches for PEDOT and PEDOT:PSS films with the aim of integrating biomolecules for the fabrication of bioelectronics platforms. As the choice of the strategy is determined by the conducting polymer synthesis method, initially PEDOT and PEDOT:PSS films preparation methods are presented. Later, a wide variety of PEDOT functionalization approaches are discussed, together with bioconjugation techniques to develop efficient organic-biological interfaces. Finally, and by making use of these approaches, the fabrication of different platforms towards organic bioelectronics devices is reviewed.
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35

OHRUI, Hiroshi. "Strategies for Development of Fluorescent Derivatization Reagents for Highly Sensitive Analysis of Biomolecules." Journal of Synthetic Organic Chemistry, Japan 56, no. 7 (1998): 591–603. http://dx.doi.org/10.5059/yukigoseikyokaishi.56.591.

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36

Akhtar, Rabia, Ameer Fawad Zahoor, Bushra Parveen, and Muhammad Suleman. "Development of environmental friendly synthetic strategies for Sonogashira cross coupling reaction: An update." Synthetic Communications 49, no. 2 (October 4, 2018): 167–92. http://dx.doi.org/10.1080/00397911.2018.1514636.

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37

Ranjan, Prabhat, Serena Pillitteri, Erik V. Van der Eycken, and Upendra K. Sharma. "Photochemical methods for deuterium labelling of organic molecules." Green Chemistry 22, no. 22 (2020): 7725–36. http://dx.doi.org/10.1039/d0gc02901g.

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38

Zhang, Yugen, Jinquan Wang, and Siti Nurhanna Riduan. "Strategies toward improving the performance of organic electrodes in rechargeable lithium (sodium) batteries." Journal of Materials Chemistry A 4, no. 39 (2016): 14902–14. http://dx.doi.org/10.1039/c6ta05231b.

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39

Zeidan, Nicolas, and Mark Lautens. "Migratory Insertion Strategies for Dearomatization." Synthesis 51, no. 22 (August 26, 2019): 4137–46. http://dx.doi.org/10.1055/s-0037-1611918.

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Development of strategies for molecule functionalization by dearomatization has surged in the last two decades. The benefits of overcoming the resonance stabilization energy outweigh the cost; diverse compounds could be accessed in a short number of steps. One approach that has been of interest in recent years is the dearomatization of indoles and other (hetero)aromatic compounds by migratory insertion. The chiral σ-bond palladium intermediate could be reduced or trapped by a second functionalization. In this short review we will summarize the recently discovered reactions from our group and others in this field of metal-catalyzed dearomatizations by migratory insertion.1 Introduction2 Monofunctionalizations: Heck and Reductive Heck Reactions2.1 N-Tethered Heterocycles2.2 Non-N-tethered Heterocycles2.3 Non-heterocycles3 Dearomative Difunctionalizations: Interrupted Heck Reaction3.1 N-Tethered Heterocycles3.2 Non-N-tethered Heterocycles4 Conclusion
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40

Mukhopadhyay, Subhabrata, Olivia Basu, Rajendar Nasani, and Samar K. Das. "Evolution of metal organic frameworks as electrocatalysts for water oxidation." Chemical Communications 56, no. 79 (2020): 11735–48. http://dx.doi.org/10.1039/d0cc03659e.

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41

Neha, Ashish Ranjan Dwivedi, Rakesh Kumar, and Vinod Kumar. "Recent Synthetic Strategies for Monocyclic Azole Nucleus and Its Role in Drug Discovery and Development." Current Organic Synthesis 15, no. 3 (April 27, 2018): 321–40. http://dx.doi.org/10.2174/1570179414666171013154337.

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Background: In recent years, the development and diversification of heterocyclic compounds has become central to the discovery of bioactive compounds with novel or improved pharmacological properties. In particular, N-containing heterocycles are proved to be promising leads and drug candidates, and received huge attention of the medicinal chemists. Objective: Many drugs especially antibiotics are becoming obsolete due to the development of multidrug resistance. Moreover, toxicity and other side effects of some drugs necessitated the quest for safer and more potent drug candidates. The current review article described biological potential of various monocyclic azoles. Recent developments in the synthesis of azole derivatives have been also reviewed. Conclusion: The presence of N-heterocyclic rings can influence the pharmacokinetics, pharmacodynamics, pKa and bioavailability profile of the drug molecules. Compounds containing monocyclic azole rings showed various biological activities and number of molecules are in clinical practice. A number of important leads and potential drug candidates containing azole nucleus are in advance stages of drug developments. Thus, simple, atom economic and more efficient synthetic strategies are desired for the synthesis of new libraries of the compounds.
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42

He, Zhi, Tong Shu, Lei Su, and Xueji Zhang. "Strategies of Luminescent Gold Nanoclusters for Chemo-/Bio-Sensing." Molecules 24, no. 17 (August 22, 2019): 3045. http://dx.doi.org/10.3390/molecules24173045.

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Recent booming advances in luminescent gold nanoclusters (AuNCs), have prompted the development of novel fluorescent sensors. The luminescent AuNCs possess unique and intriguing physical and chemical properties including responsive photoluminescence and peroxide-like activity, providing abundant potentials for sensing strategy design. As of now, a wide variety of chem-/bio-sensors based on AuNCs have been developed and reviewed according to varied analytes. In this review, from a different point of view, we follow the route of how those sensors realize their functions and focus on the actual roles AuNCs play, in order to hierarchically and logically display the recent progress in the sensing applications of AuNCs. This review not only opens new windows to understand the development of sensors based on AuNCs but can also inspire broader and deeper utilization of luminescent nanomaterials.
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43

Cheng, Hong-Bo, Yuanyuan Li, Ben Zhong Tang, and Juyoung Yoon. "Assembly strategies of organic-based imaging agents for fluorescence and photoacoustic bioimaging applications." Chemical Society Reviews 49, no. 1 (2020): 21–31. http://dx.doi.org/10.1039/c9cs00326f.

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The results of numerous studies have led to the development of assembled organic substances for fluorescence and photoacoustic bioimaging as part of comprehensive approaches to the diagnosis of diseases.
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44

Wulandari, S., Y. Ferry, and A. M. Hasibuan. "Strategies to optimize the use of organic fertilizers in smallholder coffee plantation." IOP Conference Series: Earth and Environmental Science 974, no. 1 (January 1, 2022): 012106. http://dx.doi.org/10.1088/1755-1315/974/1/012106.

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Abstract The demand for organic coffee is increasing in line with increasing competition and consumer preferences for healthier products. On the other hand, the application of organic fertilizers in smallholder coffee plantations is still low. The research aims to map the constraints of organic fertilizers usage and develop strategies to accelerate organic fertilizers application in smallholder coffee plantations. Data analysis was performed using the scoring method. The results showed that farmers applied more inorganic fertilizers. Constraints of organic fertilizers application are related to technical, economic, and institutional aspects. Strategies to optimize the use of organic fertilizers in smallholder coffee plantations include providing capital and financial support with subsidized interest rates and strengthening farmer institutions as the priority. Other strategies include introducing an integrated coffee livestock system and providing local government incentives for promoting and organic certification assistance. Institutions involved in implementing the strategy include local governments, research institutes, financial institutions, coffee processing industries, exporters, extension officers, certification bodies, farmers’ groups, cooperatives, and associations. The strategies are essential to overcome the existing problems and constraints in organic coffee farming development and increase farmers’ interest in applying organic fertilizers.
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45

Lee, Yoon Ho, O. Young Kweon, Hongki Kim, Jong Heun Yoo, Seul Gi Han, and Joon Hak Oh. "Recent advances in organic sensors for health self-monitoring systems." Journal of Materials Chemistry C 6, no. 32 (2018): 8569–612. http://dx.doi.org/10.1039/c8tc02230e.

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46

Busck, Ole, and Johannes Dragsbaek Schmidt. "Development, Ecology and Climate Change: Resistance by the Peasantry." Journal of Development Policy and Practice 5, no. 1 (January 2020): 9–31. http://dx.doi.org/10.1177/2455133320909912.

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Critical theory like political ecology and peasant studies point to the insufficiency of adaptation strategies and call for more radical alternatives, such as the abandonment of development strategies based on fossil-fuelled industrialisation and urban-centred economic growth. They favour rural livelihood strategies based on sustainable natural resource management and organic/agro-ecological production, thus combining genuine development with resistance to the hegemony of that neoliberal-driven transformation of fundamental socio-economic structures in developing countries. This is associated with detrimental climatic and ecological consequences. This article offers a theoretical and conceptual framework for understanding the nexus of development, ecology and climate change, and explores significant patterns of community resistance evolving into promising strategies of reactions ‘from below’ against growth-driven development implicating ecocide. Such resistance opposes the regional and global obsession with excessive growth and poses new challenges to the international political system.
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47

Zhang, Yun, Ling Wang, Xinqiao Wang, Chengyun Zhang, Jiamin Ge, Jing Tang, An Su, and Hongliang Duan. "Data augmentation and transfer learning strategies for reaction prediction in low chemical data regimes." Organic Chemistry Frontiers 8, no. 7 (2021): 1415–23. http://dx.doi.org/10.1039/d0qo01636e.

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48

Sharma, Anjali, Sharad Wakode, Supriya Sharma, Faizana Fayaz, and Faheem Hyder Pottoo. "Methods and Strategies Used in Green Chemistry: A Review." Current Organic Chemistry 24, no. 22 (December 18, 2020): 2555–65. http://dx.doi.org/10.2174/1385272824999200802025233.

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Green chemistry plays an important role in the development of sustainable production systems which involves tremendous research efforts on the design of synthetic and analytical techniques through resource-efficient ways. The improvement in synthetic reaction performances encourages the modern society to minimize energy and reagent consumption and waste generation. Explosion of the chemicals are referred as extremely toxic substances and have been allied with major harmful health effects, though no cure has been established due to the lack of curative therapeutic approaches. In view of the facts, green chemistry strategies trigger a new hope in the synthesis of safer biologically active compounds to meet the demands of disease free environment. Here, we highlighted the development of various compounds and greener techniques such as ultrasoundassisted method, microwave-assisted method, green solvent reactions, solvent free reactions, biomolecules and nanoformulations as a new healthy approach.
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49

Vlacholia, Maria, Stella Vosniadou, Petros Roussos, Katerina Salta, Smaragda Kazi, Michael Sigalas, and Chryssa Tzougraki. "Changes in visual/spatial and analytic strategy use in organic chemistry with the development of expertise." Chemistry Education Research and Practice 18, no. 4 (2017): 763–73. http://dx.doi.org/10.1039/c7rp00036g.

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We present two studies that investigated the adoption of visual/spatial and analytic strategies by individuals at different levels of expertise in the area of organic chemistry, using the Visual Analytic Chemistry Task (VACT). The VACT allows the direct detection of analytic strategy use without drawing inferences about underlying mental processes. The first study examined the psychometric properties of the VACT and revealed a structure consistent with the hypothesis that it consists of two sub-scales: visual/spatial and analytic. The second study investigated the performance of 285 participants with various levels of expertise in organic chemistry on the VACT. The results showed that the adoption of analytic strategies in organic chemistry, and specifically in molecular structure, was difficult and was systematically used only by the more expert participants. The implications of this research for the teaching of chemistry are discussed.
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50

Skolnick, P. "Modulation of glutamate receptors: Strategies for the development of novel antidepressants." Amino Acids 23, no. 1-3 (September 1, 2002): 153–59. http://dx.doi.org/10.1007/s00726-001-0121-7.

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