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Статті в журналах з теми "Oral lubrication"

Автор: Grafiati

Опубліковано: 21 грудня 2024

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1

Sarkar, Anwesha, Efren Andablo-Reyes, Michael Bryant, Duncan Dowson, and Anne Neville. "Lubrication of soft oral surfaces." Current Opinion in Colloid & Interface Science 39 (February 2019): 61–75. http://dx.doi.org/10.1016/j.cocis.2019.01.008.

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2

Rodrigues, S. A., N. Selway, M. P. Morgenstern, L. Motoi, J. R. Stokes, and B. J. James. "Lubrication of chocolate during oral processing." Food & Function 8, no. 2 (2017): 533–44. http://dx.doi.org/10.1039/c6fo00950f.

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3

Higham, Susan M. "Patient preferences of an intra-oral lubricating device over other dry mouth lubrication methods." British Dental Journal 193, no. 7 (October 2002): 394. http://dx.doi.org/10.1038/sj.bdj.4801574.

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4

Austin, William, Maryam Hdeib, Paige Fraser, Maya Goldchtaub, Elika Shams, Tianyi Han, Pierre-Luc Michaud, and Vahid Adibnia. "Oral Lubrication, Xerostomia, and Advanced Macromolecular Lubricants for Treatment of Dry Mouth." Lubricants 12, no. 4 (April 12, 2024): 126. http://dx.doi.org/10.3390/lubricants12040126.

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Анотація:

Dry mouth, also known as xerostomia, is a condition in which insufficient or ineffective saliva does not provide sufficient oral lubrication. The severity of this condition can vary from a mild discomfort to a debilitating condition that greatly impairs patients’ lives. Xerostomia arises as a side effect of various medications, diseases, radiation therapy, chemotherapy, or nerve damage. Various aqueous dispersions of macromolecules have been proposed to assist or replace the saliva in these patients. It is vital that these macromolecules have ample lubricity and water retention properties while showing long-lasting efficacy. The emphasis of this review is to provide a general overview on lubricating macromolecules that have been clinically used or reported in the literature as potential replacements for saliva. These include various natural or synthetic polymers, proteins, peptides, and lipids that are used in the form of solutions, gels, emulsions, and colloids. Perspectives into the future of macromolecular oral lubricants in the treatment of xerostomia are also provided.

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5

Sharma, Prashant K., Jeroen Vinke, Marijn Oude Elberink, Monique A. Stokman, Frans G. M. Kroese, Kamran Nazmi, Floris J. Bikker, Henny C. van der Mei, and Arjan Vissink. "Biotribological properties of xerostomia patient saliva and its enhancement." BIO Web of Conferences 41 (2021): 02007. http://dx.doi.org/10.1051/bioconf/20214102007.

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The study aimed to quantify the lubricating properties of chewing stimulated whole saliva from healthy controls (n=22), from patients suffering from primary Sjögren’s syndrome (n=37) and from patients undergoing head-and-neck radiotherapy (n=34). Materials and Methods All participants had to complete the Xerostomia Inventory questionnaire to score dry mouth sensation. Lubrication was measured using an ex vivo tongue-enamel friction system in terms of Relief and Relief period. MUC5b and total protein concentrations of the saliva samples were measured by an enzyme-linked immunosorbent assay and a bicinchoninic acid assay, respectively. Results Relief of Sjögren’s patients saliva and post-irradiation patients saliva was similar compared with healthy controls, but saliva from post-irradiation patients lubricated significantly better than saliva from Sjögren’s patients. The Relief period was similar between the three groups. The Relief and Relief period were higher for saliva samples post-irradiation compared to pre-irradiation. MUC5b and total protein concentrations were comparable in all groups. MUC5b and total protein output were significantly lower in patients subjected to radiotherapy compared to saliva from healthy controls and pre-irradiation patients. MUC5b concentrations positively correlated with lubricating properties of post-irradiation patient saliva. Conclusions The lubricating properties of patient saliva were not any worse than healthy controls. Lower flow rate leads to lower availability of saliva in the oral cavity and decreases the overall output of protein and MUC5b, which might result in an insufficient replenishing of the mucosal salivary film. Clinical Relevance An insufficient replenishing might underlie the sensation of a dry mouth and loss of oral function. In the talk I will explain biomaterials related strategies, yet ex vivo, to enhance salivary lubrication despite of low flowrates.

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6

Xu, Wenhu, Qixiang Xu, and Min Zhong. "Lubrication study of representative fluid foods between mimicked oral surfaces." Journal of Texture Studies 53, no. 1 (November 21, 2021): 96–107. http://dx.doi.org/10.1111/jtxs.12645.

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7

Carpenter, G., S. Bozorgi, S. Vladescu, A. E. Forte, C. Myant, R. V. Potineni, T. Reddyhoff, and S. K. Baier. "A study of saliva lubrication using a compliant oral mimic." Food Hydrocolloids 92 (July 2019): 10–18. http://dx.doi.org/10.1016/j.foodhyd.2019.01.049.

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8

Samiyoshi, S., S. Tsutsumi, S. Shimoda, and T. Honda. "Biomechanical simulation of the TMJ — Role of lubrication." International Journal of Oral and Maxillofacial Surgery 26 (January 1997): 272. http://dx.doi.org/10.1016/s0901-5027(97)81642-6.

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9

Carter, Derrick R., and Jerome C. Donnelly. "The effect of dowel lubrication on retention of resin-cemented dowels." Journal of Prosthetic Dentistry 72, no. 3 (September 1994): 255–58. http://dx.doi.org/10.1016/0022-3913(94)90338-7.

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10

Almeida, Fabrício Anderson Carvalho, Anna Paula Costa Ponte Sousa Carvalho Almeida, Flávia Lucisano Botelho Amaral, Roberta Tarkany Basting, Fabiana Mantovani Gomes França, and Cecilia Pedroso Turssi. "Lubricating conditions: effects on friction between orthodontic brackets and archwires with different cross-sections." Dental Press Journal of Orthodontics 24, no. 2 (April 2019): 66–72. http://dx.doi.org/10.1590/2177-6709.24.2.066-072.oar.

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Анотація:

Abstract Objective: This study investigated the effect of the condition of lubrication on the friction between brackets and NiTi archwires of different rounded cross-sections. Methods: Brackets (Roth, GAC) were affixed to a device connected to a universal testing machine into which segments of archwire were placed (NiTi, Nitinol, GAC) with cross-sections of 0.012-in, 0.016-in and 0.020-in. Once the wire was in the bracket slot, the following lubricants were applied: human saliva (HS: positive control), distilled water (DI), mucin-based (MUC) or carboxymethylcellulose-based (CMC) artificial saliva. In the negative control group, no lubricant was used. The combination between the wire cross-sections and the lubrication condition generated 15 groups with 15 samples each. Data were submitted to two-way analysis of variance and Tukey’s test. Results: There was no significant interaction between the wire cross-section and the condition of lubrication (p= 0.901). Irrespective of whether lubricants were used or not, there was a significant increase in friction with an increase in the cross-section of the wire (p< 0.001). For any wire, the group tested in the presence of MUC was not different from that in which HS was applied. On the other hand, when the application of lubricants was suppressed, significantly higher friction values were observed. The CMC group and the DI group demonstrated intermediate behavior. Conclusions: Friction increased with the increase of the cross-section of the NiTi archwire, but regardless of the archwire, friction with MUC artificial saliva was similar to that of HS and lower than in dry conditions.

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11

Vinke, Jeroen, Hans J. Kaper, Arjan Vissink, and Prashant K. Sharma. "Dry mouth: saliva substitutes which adsorb and modify existing salivary condition films improve oral lubrication." Clinical Oral Investigations 24, no. 11 (April 17, 2020): 4019–30. http://dx.doi.org/10.1007/s00784-020-03272-x.

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Abstract Objectives The aims of this study are to assess different saliva substitutes for their efficacy to lubricate the oral cavity, and to relate this oral lubrication to the ability of saliva substitutes to adsorb on and change the structure of the existing salivary conditioning film (SCF). Materials and methods Quartz crystal microbalance with dissipation was used to study the capability of saliva substitutes to interact with natural SCF and the ability to change the secondary SCF (S-SCF). A tongue-enamel friction system mimicking xerostomic conditions was used to assess the relief and relief period expected from these substitutes under set circumstances. Results Saliva Orthana spray, Biotène spray and Gum Hydral gel had an immediate effect on a SCF, increasing its structural softness. BioXtra gel, Biotène gel, Gum Hydral gel and Glandosane spray changed the S-SCF by increasing salivary protein adsorption, while others showed no sign of interaction. With respect to relief, only 2 out of the 16 saliva substitutes tested (Saliva Orthana spray and Gum Hydral gel) performed better than water. Overall, relief period correlated positively to structural softness change, whereas a positive correlation was seen between relief and mass adsorption. Conclusions The majority of saliva substitutes did not adsorb on the SCF, thus did not enhance lubrication. Only saliva substitutes containing carrageenan, carboxymethylcellulose, pig gastric mucin, xanthan gum and carbomer performed better in enhancing oral lubrication. Clinical relevance This objective assessment will help clinicians and patients make better choice of saliva substitutes. This study provides a scientific basis for future improvement in saliva substitutes.

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12

Mo, Linyi, Jianshe Chen, and Xinmiao Wang. "A novel experimental set up for in situ oral lubrication measurements." Food Hydrocolloids 95 (October 2019): 396–405. http://dx.doi.org/10.1016/j.foodhyd.2019.04.055.

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13

Rossetti, D., J. H. H. Bongaerts, E. Wantling, J. R. Stokes, and A. M. Williamson. "Astringency of tea catechins: More than an oral lubrication tactile percept." Food Hydrocolloids 23, no. 7 (October 2009): 1984–92. http://dx.doi.org/10.1016/j.foodhyd.2009.03.001.

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14

Zussman, E., A. L. Yarin, and R. M. Nagler. "Age- and Flow-dependency of Salivary Viscoelasticity." Journal of Dental Research 86, no. 3 (March 2007): 281–85. http://dx.doi.org/10.1177/154405910708600316.

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Анотація:

Measuring salivary viscoelasticity (by relaxation times) is of paramount importance, since salivary rheology behavior has been associated with the development of oral disease conditions (such as dental caries) in animal and human model studies. In addition, novel and improved methods to evaluate salivary distribution and lubrication are of clinical interest. We used a novel method for measuring the viscoelasticity of saliva secreted from the different glands, at rest or under stimulation and at different ages, all conditions where different viscoelastic properties might be clinically important. Submandibular/sublingual salivary viscoelasticity was significantly higher than that of parotid saliva, especially under stimulation. In addition, an age-related reduction in flow rate (by 62%) was demonstrated, accompanied by an increase in both relaxation time (by 54%) and protein (by 48%). Increased salivary viscoelasticity results in compromised salivary rheology and lubrication properties, which may render the oral cavities of the elderly and other xerostomic persons more vulnerable.

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15

Yu, Hai Yang, Shan Shan Gao, Zhen Bing Cai, and Min Hao Zhu. "The Influence of Antagonist Radii on Friction and Wear of Dental Ceramics." Key Engineering Materials 330-332 (February 2007): 1255–58. http://dx.doi.org/10.4028/www.scientific.net/kem.330-332.1255.

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The friction and wear behavior of dental ceramics (Vita VMK95) against uniform Si3N4 balls has been investigated using a small amplitude reciprocating apparatus under simulated oral conditions. The variables of ball radii (2mm, 6 mm, 13mm, and 21mm), load (10N, 20N, 30N, and 40N), reciprocating amplitude (200(m), frequency (2Hz) and use of artificial saliva lubrication or no lubrication were selected. Tests lasting up to 10,000 cycles were conducted. The wear scars of the samples were characterized with 3-D con focused laser-scanning microscope. The wear depths were analyzed statistically. The correlations between the wear behaviors and antagonist radii were also compared. The results show the friction coefficient of dental porcelain goes up with the decreasing of antagonist radii, and the wear depth decreases with the antagonist diameters. Load and lubrication effect is significant for friction coefficient and wear depth. The friction and wear mechanism of dental ceramics was characterized by abrasive wear and delaminating.

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16

Sun, Limei, Junwu Liu, and Lin Zhang. "Evaluation of friction in different oral restoration materials and its influencing factors." Materials Express 10, no. 10 (October 31, 2020): 1746–52. http://dx.doi.org/10.1166/mex.2020.1790.

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This research uses nanotechnology and molecular assembly technology, using biocompatible hydroxyapatite material as the inorganic filler, organically compound and assemble with the organic resin matrix to achieve the performance shear of the composite material, thus developing strength High-resistance, easy-to-process and good biocompatibility composite resin dental restoration materials, and the nano-composite resin material flexural strength, compressive strength and water absorption value were characterized in laboratory stage, the performance fully reached the current clinical use Various indicators of imported composite resin. This study analyzed the differences in the effects and friction properties of different prosthetic materials in oral repair. In order to better simulate the friction and wear performance of dental restoration materials in the oral environment, this paper studied under two conditions of oil lubrication and artificial saliva lubrication, and the wear mechanism from the macro aspects of friction coefficient, wear rate, wear resistance, etc. The research results show that the abrasion performance of the nanocomposite resin is closely related to its surface morphology and characteristics. The comparison with the performance of ceramic and composite resin restoration materials shows that nanocomposite resin materials have better mechanical properties and resistance than other dental restoration wear performance.

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17

Reeh, Ernest S., William H. Douglas, and Michael J. Levine. "Lubrication of saliva substitutes at enamel-to-enamel contacts in an artificial mouth." Journal of Prosthetic Dentistry 75, no. 6 (June 1996): 649–56. http://dx.doi.org/10.1016/s0022-3913(96)90251-6.

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18

Wan, H., A. Vissink, and P. K. Sharma. "Enhancement in Xerostomia Patient Salivary Lubrication Using a Mucoadhesive." Journal of Dental Research 99, no. 8 (May 6, 2020): 914–21. http://dx.doi.org/10.1177/0022034520917675.

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Oral lubrication mediated by mucin and protein containing salivary conditioning films (SCFs) with strong water retainability can get impaired due to disease such as xerostomia, that is, a subjective dry mouth feel associated with the changed salivary composition and low salivary flow rate. Aberrant SCFs in xerostomia patient cause difficulties in speech, mastication, and dental erosion while the prescribed artificial saliva is inadequate to solve the complications on a lasting basis. With the growing aging population, it is urgently needed to propose a new strategy to restore oral lubrication. Existing saliva substitutes often overwhelm the aberrant SCFs, generating inadequate relief. Here we demonstrated that the function of aberrant SCFs in a patient with Sjögren syndrome can be boosted through mucin recruitment by a simple mucoadhesive, chitosan-catechol (Chi-C). Chi-C with different conjugation degrees (Chi-C7.6%, Chi-C14.5%, Chi-C22.4%) was obtained by carbodiimide chemistry, which induced a layered structure composed of a rigid bottom and a soft secondary SCF (S-SCF) after reflow of saliva. The higher conjugation degree of Chi-C generates a higher glycosylated S-SCF by mucin recruitment and a lower friction in vitro. The layered S-SCF extends the “relief period” for Sjögren patient saliva over 7-fold, measured on an ex vivo tongue-enamel friction system. Besides lubrication, Chi-C-treated S-SCF reduces dental erosion depths from 125 to 70 μm. Chi-C shows antimicrobial activity against Streptococcus mutans. This research provides a new key insight in restoring the functionality of conditioning film at articulating tissues in living systems.

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19

de Hoog, Els H. A., Jon F. Prinz, Linda Huntjens, Diane M. Dresselhuis, and George A. van Aken. "Lubrication of Oral Surfaces by Food Emulsions: the Importance of Surface Characteristics." Journal of Food Science 71, no. 7 (September 2006): E337—E341. http://dx.doi.org/10.1111/j.1750-3841.2006.00140.x.

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20

Olin, Paul S., Andrew Cederbaum, and James L. Donahue. "Effects of lubrication on the retention of tapered and parallel cast post and cores." Journal of Prosthetic Dentistry 66, no. 1 (July 1991): 45–49. http://dx.doi.org/10.1016/0022-3913(91)90350-6.

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21

Vinke, Jeroen, Marijn Oude Elberink, Monique A. Stokman, Frans G. M. Kroese, Kamran Nazmi, Floris J. Bikker, Henny C. van der Mei, Arjan Vissink, and Prashant K. Sharma. "Lubricating properties of chewing stimulated whole saliva from patients suffering from xerostomia." Clinical Oral Investigations 25, no. 7 (March 4, 2021): 4459–69. http://dx.doi.org/10.1007/s00784-020-03758-8.

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Анотація:

Abstract Objectives The study aimed to quantify the lubricating properties of chewing stimulated whole saliva from healthy controls (n = 22), from patients suffering from primary Sjögren’s syndrome (n = 37) and from patients undergoing head-and-neck radiotherapy (n = 34). Materials and methods All participants had to complete the Xerostomia Inventory questionnaire to score dry mouth sensation. Lubrication was measured using an ex vivo tongue-enamel friction system in terms of Relief and Relief period. MUC5b and total protein concentrations of the saliva samples were measured by an enzyme-linked immunosorbent assay and a bicinchoninic acid assay, respectively. Results Relief of Sjögren’s patients’ saliva and post-irradiation patients’ saliva was similar compared with healthy controls, but saliva from post-irradiation patients lubricated significantly better than saliva from Sjögren’s patients. The Relief period was similar between the three groups. The Relief and Relief period were higher for saliva samples post-irradiation compared to pre-irradiation. MUC5b and total protein concentrations were comparable in all groups. MUC5b and total protein output were significantly lower in patients subjected to radiotherapy compared to saliva from healthy controls and pre-irradiation patients. MUC5b concentrations positively correlated with lubricating properties of post-irradiation patient saliva. Conclusions The lubricating properties of patient saliva were not any worse than healthy controls. Lower flow rate leads to lower availability of saliva in the oral cavity and decreases the overall output of protein and MUC5b, which might result in an insufficient replenishing of the mucosal salivary film. Clinical relevance An insufficient replenishing might underlie the sensation of a dry mouth and loss of oral function.

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22

Malone, M. E., I. A. M. Appelqvist, and I. T. Norton. "Oral behaviour of food hydrocolloids and emulsions. Part 1. Lubrication and deposition considerations." Food Hydrocolloids 17, no. 6 (November 2003): 763–73. http://dx.doi.org/10.1016/s0268-005x(03)00097-3.

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23

Krop, Emma M., Marion M. Hetherington, Sophie Miquel, and Anwesha Sarkar. "The influence of oral lubrication on food intake: A proof-of-concept study." Food Quality and Preference 74 (June 2019): 118–24. http://dx.doi.org/10.1016/j.foodqual.2019.01.016.

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24

Siqueira, W. L., W. Custodio, and E. E. McDonald. "New Insights into the Composition and Functions of the Acquired Enamel Pellicle." Journal of Dental Research 91, no. 12 (September 26, 2012): 1110–18. http://dx.doi.org/10.1177/0022034512462578.

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Анотація:

The acquired enamel pellicle (AEP) is a thin acellular film that forms on tooth surfaces upon exposure to the oral environment. It consists predominantly of salivary proteins, but also includes non-salivary-derived proteins, carbohydrates, and lipids. Since it is the interface between teeth and the oral environment, the AEP plays a key role in the maintenance of oral health by regulating processes including lubrication, demineralization, and remineralization and shaping the composition of early microbial flora adhering to tooth surfaces. Knowledge of the 3D structure of the AEP and how that correlates with its protective functions may provide insight into several oral pathological states, including caries, erosion, and periodontal disease. This review intends to update readers about the latest discoveries related to the formation, ultrastructure, composition, and functions of the AEP, as well as the future of pellicle research, with particular emphasis on the emerging role of proteomic and microscopy techniques in oral diagnosis and therapeutics.

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25

Hatton, Michael N., Michael J. Levine, Joseph E. Margarone, and Alfredo Aguirre. "Lubrication and viscosity features of human saliva and commercially available saliva substitutes." Journal of Oral and Maxillofacial Surgery 45, no. 6 (June 1987): 496–99. http://dx.doi.org/10.1016/s0278-2391(87)80009-5.

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26

Suzuki, Akiko, and Junichi Iwata. "Molecular Regulatory Mechanism of Exocytosis in the Salivary Glands." International Journal of Molecular Sciences 19, no. 10 (October 17, 2018): 3208. http://dx.doi.org/10.3390/ijms19103208.

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Анотація:

Every day, salivary glands produce about 0.5 to 1.5 L of saliva, which contains salivary proteins that are essential for oral health. The contents of saliva, 0.3% proteins (1.5 to 4.5 g) in fluid, help prevent oral infections, provide lubrication, aid digestion, and maintain oral health. Acinar cells in the lobular salivary glands secrete prepackaged secretory granules that contain salivary components such as amylase, mucins, and immunoglobulins. Despite the important physiological functions of salivary proteins, we know very little about the regulatory mechanisms of their secretion via exocytosis, which is a process essential for the secretion of functional proteins, not only in salivary glands, but also in other secretory organs, including lacrimal and mammary glands, the pancreas, and prostate. In this review, we discuss recent findings that elucidate exocytosis by exocrine glands, especially focusing on the salivary glands, in physiological and pathological conditions.

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27

Herd, M. Kerry, Rajiv Anand, and Peter A. Brennan. "Use of propofol emulsion for intra-operative lubrication of oral and maxillofacial surgical instruments." British Journal of Oral and Maxillofacial Surgery 49, no. 8 (December 2011): 666–67. http://dx.doi.org/10.1016/j.bjoms.2010.12.003.

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28

Walmann, James O., and Jerome C. Donnelly. "Effect of dowel lubrication on resistance to dislodgment of dowels cemented with a 4-META resinous cement." Journal of Prosthetic Dentistry 76, no. 1 (July 1996): 15–18. http://dx.doi.org/10.1016/s0022-3913(96)90339-x.

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29

Patil, Priyanka, Madhav VNV, and Manisha Kulkarni. "A Novel Technique of incorporating Salivary Reservoir in a Complete Denture Patient: A Case Report." JOURNAL OF CLINICAL PROSTHODONTICS AND IMPLANTOLOGY 2, no. 2 (December 30, 2020): 11–14. http://dx.doi.org/10.55995/j-cpi.2020009.

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Анотація:

Xerostomia is usually associated with systemic health problems. The most common difficulty of xerostomia patients is intolerance and poor retention in removable dentures due to dry mouth, mucositis, glossitis, and lack of thin salivary film. The presented case report describes the new technique of incorporating a salivary reservoir in a maxillary complete denture. The technique of fabrication is simple, cost-effective, provides good lubrication to oral tissue, and easy to clean and maintain by the patient.

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30

Ann, David K., and H. Helen Lin. "Macaque Salivary Proline-Rich Protein: Structure, Evolution, and Expression." Critical Reviews in Oral Biology & Medicine 4, no. 3 (April 1993): 545–51. http://dx.doi.org/10.1177/10454411930040034101.

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Proline-rich proteins are a family of proteins that exhibit unique features including an unusual high proline content and salivary-specificity. As a major constituent in the salivary secretion of higher primates, proline-rich proteins may have biological roles in oral lubrication and protection. In this article, the genomic structure and regulation by cAMP of one of the macaque salivary proline-rich protein genes, MnP4, is reviewed. The evolution of this multigene family of proteins is also discussed.

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31

SHIMOKASA, Kenji, Hiromichi OBARA, and Hiroshi MIZUNUMA. "Lubrication of saliva layer on oral and throat mucosa and its friction reduction effect." Proceedings of the Fluids engineering conference 2020 (2020): OS10–04. http://dx.doi.org/10.1299/jsmefed.2020.os10-04.

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32

彭, 泽燕. "Observation on the Effect of Throat Lubrication Spray Combined with Medication on Oral Dryness." Traditional Chinese Medicine 07, no. 01 (2018): 43–50. http://dx.doi.org/10.12677/tcm.2018.71008.

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33

Yanuar Kristanto, Bryan, Endah Kusumastuti, and Dzanuar Rahmawan. "Effect of consuming young coconut water (Cocos nucifera) on saliva pH levels in the oral cavity." World Journal of Advanced Research and Reviews 19, no. 1 (July 30, 2023): 721–26. http://dx.doi.org/10.30574/wjarr.2023.19.1.1411.

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including lubrication, fluid balance, prevention of pathogenic bacteria, and maintenance of oral pH to prevent cavities. The balance between acidity and alkalinity in saliva is very important for the function of the oral cavity, with a normal pH range of 6.8 to 7.0. In Indonesia, young coconut water is a drink that is often consumed and easily available with a pH of around 5.5, containing potassium, sodium, calcium, vitamin C, and reducing sugars. Purpose: This study aims to determine the impact of consuming young coconut water (Cocos Nucifera) on the pH level of saliva in the oral cavity. Methods: This research is pre-experimental with pretest and posttest design. The research sample consisted of 30 dental students from the Faculty of Dentistry, Institute of Health Sciences Bhakti Wiyata Kediri in 2019, 2020, 2021 and 2022, who met the sample criteria. Results: Data were analyzed using the parametric Paired T-Test hypothesis test, with a significance value of 0.000. Conclusion: Young coconut water consumption has an impact on changes in the salivary pH level in the oral cavity.

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Wang, Qi, Xinmiao Wang, and Jianshe Chen. "A new design of soft texture analyzer tribometer (STAT) for in vitro oral lubrication study." Food Hydrocolloids 110 (January 2021): 106146. http://dx.doi.org/10.1016/j.foodhyd.2020.106146.

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Han, Chuanwu, Gaoshang Wang, Jian Guo, Jinmei Wang, and Xiaoquan Yang. "Oral oil release improves lubrication and sensory properties of meat analogs with protein-stabilized oleogel." Food Hydrocolloids 142 (September 2023): 108788. http://dx.doi.org/10.1016/j.foodhyd.2023.108788.

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Pandey, Nidhi, Swati Singh, and Debarati Saha. "Vesicular contact dermatitis following sulfacetamide eye drop instillation raising the specter of vesiculobullous mucocutaneous syndrome – Case presentation." Indian Journal of Ophthalmology - Case Reports 3, no. 3 (2023): 790–92. http://dx.doi.org/10.4103/ijo.ijo_706_23.

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Allergic reactions to ocular drops are a well-known side effect and usually present as eczematous dermatitis localized to periocular skin. However, rarely, the reactions can be severe and present with systemic involvement leading to vision or even life-threatening consequences. We report a case of vesicular allergic contact dermatitis following instillation of an over-the-counter sulfacetamide eye drop in right eye with involvement of oral mucosa, raising a threat of mucocutaneous vesiculobullous disorders. Prompt discontinuation of ocular drops followed by treatment with systemic and topical steroids, topical lubrication, and fornix glass rod sweeping prevented vision- and life-threatening sequalae.

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Nitzan, Dorrit W. "The process of lubrication impairment and its involvement in temporomandibular joint disc displacement: A theoretical concept." Journal of Oral and Maxillofacial Surgery 59, no. 1 (January 2001): 36–45. http://dx.doi.org/10.1053/joms.2001.19278.

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Stribițcaia, Ecaterina, Catherine Gibbons, Joanna Sier, Christine Boesch, John Blundell, Graham Finlayson, and Anwesha Sarkar. "Effects of oral lubrication on satiety, satiation and salivary biomarkers in model foods: A pilot study." Appetite 165 (October 2021): 105427. http://dx.doi.org/10.1016/j.appet.2021.105427.

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Hayden, Richard E. "Free Flap Transfer For Restoration Of Sensation And Lubrication To The Reconstructed Oral Cavity And Pharynx." Otolaryngologic Clinics of North America 27, no. 6 (December 1994): 1185–99. http://dx.doi.org/10.1016/s0030-6665(20)30594-6.

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SHIMOKASA, Kenji, and Hiromichi OBARA. "Lubrication of saliva layer on oral and throat mucosa and its friction reduction effect of swallowing." Proceedings of the Fluids engineering conference 2022 (2022): OS10–06. http://dx.doi.org/10.1299/jsmefed.2022.os10-06.

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Jinno, Yohei, Michele Stocchero, Marco Toia, Marianne Ahmad, Tomas Albrektsson, and Jonas P. Becktor. "In vivo intraosseous temperature during implant placement‐ the influence of the drilling protocol, implant surface and surface lubrication: A study in sheep." Clinical Oral Implants Research 30, S19 (September 2019): 103. http://dx.doi.org/10.1111/clr.62_13509.

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Siddiqui, Arif, Deepa D. Deepa D, Shalabh Mehrotra, and Anjali Sharma. "Metabolomics in Periodontal Disease - A Mini Review." ENVIRO Dental Journal 4, no. 1 (July 14, 2022): 13–19. http://dx.doi.org/10.12944/edj.04.01.04.

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Periodontitis is the most common oral disease. It is a chronic disease that is characterised by the destruction of the tissues. It is caused by multifactorial aetiology. Variation in host metabolism and microbes results in the development of periodontitis. Saliva provides us with a protective role of lubrication, neutralizing the pH, mineralising the bones and fighting microbes in a diseased oral cavity. We need to identify metabolites in saliva to know the aetiology and stage of periodontitis. Some metabolites may help in the diagnosis and treatment of periodontitis. Various classes of the biochemicals like amino acids, lipids, carbohydrates, nuclear peptides, dipeptides are changed in periodontitis. Most importantly, there is an increase in the levels of protease, glycosidase and lipase activity in chronic periodontal disease that forms the most favourable time for the growth of bacteria. There is a deficiency in contempered screening methods. Therefore, we should understand the arising need for metabolites for better diagnosis and treatment of periodontitis.

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Marković, Srđan, Adrijana Serafimovka, Ivana Kostić, Marija Jovović, Maja Ribar, Branko Bugarski, and Dragana Kastratović. "Salviva®: Step forward in human saliva substitution." Hospital Pharmacology - International Multidisciplinary Journal 7, no. 3 (2020): 976–82. http://dx.doi.org/10.5937/hpimj2003976m.

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Introduction: Saliva is a product of salivary glands secretion that constantly soaks-moisturizes the teeth and mucous membranes of the oral cavity. Physiological roles of saliva are: maintaining humidity, lubrication and physiological cleaning of the oral cavity, enzymatic activity (beginning of digestion), bacteriostatic and bactericidal action, prevention of dental caries. Topic: The most serious health problem is the complete, permanent absence of saliva secretion , which is an absolute indication for daily use of an adequate preparation for moistening the oral cavity or saliva substitution. Salviva ® is sufficiently viscous and the content that can serve as natural saliva for 4 hours. 200 ml bottle is sufficient for daily patient needs and the production costs are low (0.25 EUR per unit for laboratory level volumes, excluding primary packaging costs). Conclusions: With the further innovative development of Salviva ® , it is possible to apply drugs with local and systemic effects, and thus treat the patient, which opens a completely new field of application of some drugs and reduces their side effects and unpleasant effects. The quality of life of patients as well as social functionality will be significantly improved, which is very important for the working population.

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Müller, Frauke, Najla Chebib, Sabrina Maniewicz, and Laurence Genton. "The Impact of Xerostomia on Food Choices—A Review with Clinical Recommendations." Journal of Clinical Medicine 12, no. 14 (July 10, 2023): 4592. http://dx.doi.org/10.3390/jcm12144592.

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Xerostomia and hyposalivation are highly prevalent conditions in old age, particularly among multimorbid elders, and are often attributed to the use of multiple medications. These conditions negatively affect oral functions, such as chewing, swallowing, speech, and taste. Additionally, the lack of lubrication of the oral mucosa frequently leads to super-infections with candida. Denture retention and comfort may also be compromised. The risk of dental caries and erosion of natural teeth increases since saliva, which is essential for repairing initial lesions in tooth structures, is insufficient. The dry sensation in the mouth also impacts the emotional and social well-being of elderly individuals. Patients experiencing xerostomia often avoid certain foods that are uncomfortable or difficult to consume. However, some foods may alleviate the symptoms or even stimulate salivation. This review discusses the limited available evidence on nutritional advice for patients with xerostomia and aims to provide insight into the patient’s perspective while offering clinical recommendations. Future studies should focus on investigating the nutritional intake of individuals suffering from xerostomia or hyposalivation in order to ensure oral health comfort, prevent malnutrition, and minimize the impact on their quality of life.

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Гутикова, Л. В. "Therapeutic Effects of a Combined Oral Contraceptive Containing Ethinyl Estradiol and Chlormadinone." Репродуктивное здоровье. Восточная Европа, no. 1 (March 25, 2021): 101–8. http://dx.doi.org/10.34883/pi.2021.11.1.019.

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В статье представлены данные по оценке лечебных эффектов контрацептива, содержащего этинилэстрадиол + хлормадинон, и его влияния на сексуальную активность женщин. Каждая вторая пациентка при выборе гормонального метода контрацепции считала приоритетным улучшение состояния кожи и волос, а контрацептивный эффект ставила на второе место. Применение препарата оказало статистически значимый лечебный эффект у пациенток с гиперандрогенией; влияние применения препарата на сексуальную активность выразилось в увеличении числа пациенток с усилением сексуальных ощущений и любрикации; кроме того, в 3 раза сократилось число пациенток с диспареунией. The paper presents the evaluation of therapeutic effects of Belara contraceptive (ethinyl estradiol + chlormadinone) and its impact on the sexual activity of women. Every second patient when choosing a hormonal method of contraception considered a priority the improvement of skin and hair, and the contraceptive effect was on second place. Use of the drug had a statistically significant treatment effect in patients with hyperandrogenism; the effect of the drug on sexual activity resulted in an increase in the number of patients with increased sexual sensation and lubrication; 3-times decrease in the number of patients with dyspareunia was noted.

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Sotres, Javier, and Thomas Arnebrant. "Experimental Investigations of Biological Lubrication at the Nanoscale: The Cases of Synovial Joints and the Oral Cavity." Lubricants 1, no. 4 (November 25, 2013): 102–31. http://dx.doi.org/10.3390/lubricants1040102.

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Vinke, Jeroen, Hans J. Kaper, Arjan Vissink, and Prashant K. Sharma. "Correction to: Dry mouth: saliva substitutes which adsorb and modify existing salivary condition films improve oral lubrication." Clinical Oral Investigations 24, no. 11 (June 15, 2020): 4031. http://dx.doi.org/10.1007/s00784-020-03383-5.

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Ash, A., P. J. Wilde, D. J. Bradshaw, S. P. King, and J. R. Pratten. "Structural modifications of the salivary conditioning film upon exposure to sodium bicarbonate: implications for oral lubrication and mouthfeel." Soft Matter 12, no. 10 (2016): 2794–801. http://dx.doi.org/10.1039/c5sm01936b.

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This study suggests that differences in the lubricative properties of saliva are more likely to be due to changes in the interfacial properties of the salivary conditioning film as opposed to changes in the bulk viscosity of saliva when exposed to sodium bicarbonate.

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Khan, Erum, Imran Farooq, Abdul Khabeer, Saqib Ali, Muhammad Sohail Zafar, and Zohaib Khurshid. "Salivary gland tissue engineering to attain clinical benefits: a special report." Regenerative Medicine 15, no. 3 (March 2020): 1455–61. http://dx.doi.org/10.2217/rme-2019-0079.

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The salivary glands produce saliva, which helps in mediating the oral colonization of microbes, the repair of mucosa, the remineralization of teeth, lubrication and gustation. However, certain medications, therapeutic radiation and certain autoimmune diseases can cause a reduction in the salivary flow. The aim of this report was to review and highlight the indications and techniques of salivary gland engineering to counter hyposalivation. This report concludes that in the literature, numerous strategies have been suggested and discussed pertaining to the engineering of salivary gland, however, challenges remain in terms of its production and accurate function. Dedicated efforts are required from researchers all over the world to obtain the maximum benefits from salivary gland engineering techniques.

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Gurkar, Haraswarupa, Omprakash Yadahally Venkatesh, Jagadeesh Mandya Somashekar, Muthuraj Hariharapura Lakshme Gowda, Madhavi Dwivedi, and Ishani Ningthoujam. "Prosthodontic Management of Xerostomic Patient: A Technical Modification." Case Reports in Dentistry 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/8905891.

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Xerostomia is often a contributing factor in both minor and serious health problems. It can affect nutrition and dental as well as psychological health. Common problems faced by such patients are glossitis, mucositis, angular cheilitis, dysgeusia, and difficulty in chewing and swallowing. One of the major problems associated with xerostomic patients is the poor tolerance and retention of removable dental prostheses because of thin dry atrophic mucosa and lack of a saliva film. This paper describes a new technique of incorporating a salivary reservoir in the maxillary complete denture. The salivary reservoir fabricated by this technique provided good lubrication of the oral tissues and was easily cleansed by the wearer and was fabricated from routine denture materials.

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