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Статті в журналах з теми "Optical Biosensing"

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Автор: Grafiati

Опубліковано: 6 вересня 2023

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1

Scheggi, A. M., and A. G. Mignani. "Optical fiber biosensing." Optics News 15, no. 11 (November 1, 1989): 28. http://dx.doi.org/10.1364/on.15.11.000028.

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2

Kim, Youngsun, John Gonzales, and Yuebing Zheng. "Optical Biosensing: Sensitivity‐Enhancing Strategies in Optical Biosensing (Small 4/2021)." Small 17, no. 4 (January 2021): 2170016. http://dx.doi.org/10.1002/smll.202170016.

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3

Banciu, Roberta Maria, Nimet Numan, and Alina Vasilescu. "Optical biosensing of lysozyme." Journal of Molecular Structure 1250 (February 2022): 131639. http://dx.doi.org/10.1016/j.molstruc.2021.131639.

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4

Melvin, Tracy. "Optical biosensing: future possibilities." Expert Review of Ophthalmology 2, no. 6 (December 2007): 883–87. http://dx.doi.org/10.1586/17469899.2.6.883.

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5

Bally, Marta, Martin Halter, Janos Vörös, and H. Michelle Grandin. "Optical microarray biosensing techniques." Surface and Interface Analysis 38, no. 11 (2006): 1442–58. http://dx.doi.org/10.1002/sia.2375.

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6

Barrios, Carlos, Víctor Canalejas-Tejero, Sonia Herranz, Javier Urraca, María Moreno-Bondi, Miquel Avella-Oliver, Ángel Maquieira, and Rosa Puchades. "Aluminum Nanoholes for Optical Biosensing." Biosensors 5, no. 3 (July 9, 2015): 417–31. http://dx.doi.org/10.3390/bios5030417.

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7

Chiavaioli, Francesco, Francesco Baldini, Sara Tombelli, Cosimo Trono, and Ambra Giannetti. "Biosensing with optical fiber gratings." Nanophotonics 6, no. 4 (June 7, 2017): 663–79. http://dx.doi.org/10.1515/nanoph-2016-0178.

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Анотація:

AbstractOptical fiber gratings (OFGs), especially long-period gratings (LPGs) and etched or tilted fiber Bragg gratings (FBGs), are playing an increasing role in the chemical and biochemical sensing based on the measurement of a surface refractive index (RI) change through a label-free configuration. In these devices, the electric field evanescent wave at the fiber/surrounding medium interface changes its optical properties (i.e. intensity and wavelength) as a result of the RI variation due to the interaction between a biological recognition layer deposited over the fiber and the analyte under investigation. The use of OFG-based technology platforms takes the advantages of optical fiber peculiarities, which are hardly offered by the other sensing systems, such as compactness, lightness, high compatibility with optoelectronic devices (both sources and detectors), and multiplexing and remote measurement capability as the signal is spectrally modulated. During the last decade, the growing request in practical applications pushed the technology behind the OFG-based sensors over its limits by means of the deposition of thin film overlays, nanocoatings, and nanostructures, in general. Here, we review efforts toward utilizing these nanomaterials as coatings for high-performance and low-detection limit devices. Moreover, we review the recent development in OFG-based biosensing and identify some of the key challenges for practical applications. While high-performance metrics are starting to be achieved experimentally, there are still open questions pertaining to an effective and reliable detection of small molecules, possibly up to single molecule, sensing in vivo and multi-target detection using OFG-based technology platforms.

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8

Sharma, Shubhanshi, Rashmi Kumari, Shailendra K. Varshney, and Basudev Lahiri. "Optical biosensing with electromagnetic nanostructures." Reviews in Physics 5 (November 2020): 100044. http://dx.doi.org/10.1016/j.revip.2020.100044.

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9

Yang, Xiao, Congcong Li, Peifeng Li, and Qinrui Fu. "Ratiometric optical probes for biosensing." Theranostics 13, no. 8 (2023): 2632–56. http://dx.doi.org/10.7150/thno.82323.

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10

Maniya, Nalin H. "Recent Advances in Porous Silicon Based Optical Biosensors." REVIEWS ON ADVANCED MATERIALS SCIENCE 53, no. 1 (January 1, 2018): 49–73. http://dx.doi.org/10.1515/rams-2018-0004.

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Abstract PSi structures have unique physical and optical properties, which are being exploited for a numerous biomedical applications including biosensing, bioimaging, tissue engineering, and drug delivery. Different PSi optical structures can be fabricated to improve the sensitivity of the optical measurements. A very high surface area per volume of PSi can be used for the higher loading of target analytes in a small sensor area, which helps in increasing sensitivity and allows the miniaturization of biosensor. The specificity of PSi biosensor to the target analyte can be inferred by immobilizing the corresponding bioreceptor such as DNA, enzyme, or antibody via different conjugation chemistries. Finally, PSi is biocompatible material that offers additional advantage in comparison to other sensing platforms for in vivo implantable biosensing applications. This paper reviews fabrication, surface modification, biofunctionalization, and optical biosensing applications of PSi structures with special emphasis on in vivo and PSi photonic particles biosensing.

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11

Hu, Ning, and Hao Wan. "Electrical/Optical Biosensing and Regulating Technology." Biosensors 13, no. 6 (June 8, 2023): 634. http://dx.doi.org/10.3390/bios13060634.

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12

Kumar, Santosh, Zhi Wang, Wen Zhang, Xuecheng Liu, Muyang Li, Guoru Li, Bingyuan Zhang, and Ragini Singh. "Optically Active Nanomaterials and Its Biosensing Applications—A Review." Biosensors 13, no. 1 (January 4, 2023): 85. http://dx.doi.org/10.3390/bios13010085.

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Анотація:

This article discusses optically active nanomaterials and their optical biosensing applications. In addition to enhancing their sensitivity, these nanomaterials also increase their biocompatibility. For this reason, nanomaterials, particularly those based on their chemical compositions, such as carbon-based nanomaterials, inorganic-based nanomaterials, organic-based nanomaterials, and composite-based nanomaterials for biosensing applications are investigated thoroughly. These nanomaterials are used extensively in the field of fiber optic biosensing to improve response time, detection limit, and nature of specificity. Consequently, this article describes contemporary and application-based research that will be of great use to researchers in the nanomaterial-based optical sensing field. The difficulties encountered during the synthesis, characterization, and application of nanomaterials are also enumerated, and their future prospects are outlined for the reader’s benefit.

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13

Gordon, Reuven. "[INVITED] Biosensing with nanoaperture optical tweezers." Optics & Laser Technology 109 (January 2019): 328–35. http://dx.doi.org/10.1016/j.optlastec.2018.07.019.

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14

Cassagneau, T., and F. Caruso. "Inverse Opals for Optical Affinity Biosensing." Advanced Materials 14, no. 22 (November 18, 2002): 1629–33. http://dx.doi.org/10.1002/1521-4095(20021118)14:22<1629::aid-adma1629>3.0.co;2-2.

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15

Kocheril, Philip A., Kiersten D. Lenz, David D. L. Mascareñas, John E. Morales-Garcia, Aaron S. Anderson, and Harshini Mukundan. "Portable Waveguide-Based Optical Biosensor." Biosensors 12, no. 4 (March 25, 2022): 195. http://dx.doi.org/10.3390/bios12040195.

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Rapid, on-site diagnostics allow for timely intervention and response for warfighter support, environmental monitoring, and global health needs. Portable optical biosensors are being widely pursued as a means of achieving fieldable biosensing due to the potential speed and accuracy of optical detection. We recently developed the portable engineered analytic sensor with automated sampling (PEGASUS) with the goal of developing a fieldable, generalizable biosensing platform. Here, we detail the development of PEGASUS’s sensing hardware and use a test-bed system of identical sensing hardware and software to demonstrate detection of a fluorescent conjugate at 1 nM through biotin-streptavidin chemistry.

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16

Pasche, Stéphanie, Bastien Schyrr, Bernard Wenger, Emmanuel Scolan, Réal Ischer, and Guy Voirin. "Smart Textiles with Biosensing Capabilities." Advances in Science and Technology 80 (September 2012): 129–35. http://dx.doi.org/10.4028/www.scientific.net/ast.80.129.

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Real-time, on-body measurement using minimally invasive biosensors opens up new perspectives for diagnosis and disease monitoring. Wearable sensors are placed in close contact with the body, performing analyses in accessible biological fluids (wound exudates, sweat). In this context, a network of biosensing optical fibers woven in textile enables the fabric to measure biological parameters in the surrounding medium. Optical fibers are attractive in view of their flexibility and easy integration for on-body monitoring. Biosensing fibers are obtained by modifying standard optical fibers with a sensitive layer specific to biomarkers. Detection is based on light absorption of the sensing fiber, placing a light source and a detector at both extremities of the fiber. Biosensing optical fibers have been developed for the in situ monitoring of wound healing, measuring pH and the activity of proteases in exudates. Other developments aim at the design of sensing patches based on functionalized, porous sol-gel layers, which can be deposited onto textiles and show optical changes in response to biomarkers. Biosensing textiles present interesting perspectives for innovative healthcare monitoring. Wearable sensors will provide access to new information from the body in real time, to support diagnosis and therapy.

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17

Si, Peng, Nasrin Razmi, Omer Nur, Shipra Solanki, Chandra Mouli Pandey, Rajinder K. Gupta, Bansi D. Malhotra, Magnus Willander, and Adam de la Zerda. "Gold nanomaterials for optical biosensing and bioimaging." Nanoscale Advances 3, no. 10 (2021): 2679–98. http://dx.doi.org/10.1039/d0na00961j.

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18

Li, Muyang, Ragini Singh, Yiran Wang, Carlos Marques, Bingyuan Zhang, and Santosh Kumar. "Advances in Novel Nanomaterial-Based Optical Fiber Biosensors—A Review." Biosensors 12, no. 10 (October 8, 2022): 843. http://dx.doi.org/10.3390/bios12100843.

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This article presents a concise summary of current advancements in novel nanomaterial-based optical fiber biosensors. The beneficial optical and biological properties of nanomaterials, such as nanoparticle size-dependent signal amplification, plasmon resonance, and charge-transfer capabilities, are widely used in biosensing applications. Due to the biocompatibility and bioreceptor combination, the nanomaterials enhance the sensitivity, limit of detection, specificity, and response time of sensing probes, as well as the signal-to-noise ratio of fiber optic biosensing platforms. This has established a practical method for improving the performance of fiber optic biosensors. With the aforementioned outstanding nanomaterial properties, the development of fiber optic biosensors has been efficiently promoted. This paper reviews the application of numerous novel nanomaterials in the field of optical fiber biosensing and provides a brief explanation of the fiber sensing mechanism.

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19

Li, Baocheng, Ruochong Zhang, Renzhe Bi, and Malini Olivo. "Applications of Optical Fiber in Label-Free Biosensors and Bioimaging: A Review." Biosensors 13, no. 1 (December 30, 2022): 64. http://dx.doi.org/10.3390/bios13010064.

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Biosensing and bioimaging are essential in understanding biological and pathological processes in a living system, for example, in detecting and understanding certain diseases. Optical fiber has made remarkable contributions to the biosensing and bioimaging areas due to its unique advantages of compact size, immunity to electromagnetic interference, biocompatibility, fast response, etc. This review paper will present an overview of seven common types of optical fiber biosensors and optical fiber-based ultrasound detection in photoacoustic imaging (PAI) and the applications of these technologies in biosensing and bioimaging areas. Of course, there are many types of optical fiber biosensors. Still, this paper will review the most common ones: optical fiber grating, surface plasmon resonance, Sagnac interferometer, Mach–Zehnder interferometer, Michelson interferometer, Fabry–Perot Interferometer, lossy mode resonance, and surface-enhanced Raman scattering. Furthermore, different optical fiber techniques for detecting ultrasound in PAI are summarized. Finally, the main challenges and future development direction are briefly discussed.

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20

Anne, Marie-Laure, Julie Keirsse, Virginie Nazabal, Koji Hyodo, Satoru Inoue, Catherine Boussard-Pledel, Hervé Lhermite, et al. "Chalcogenide Glass Optical Waveguides for Infrared Biosensing." Sensors 9, no. 9 (September 15, 2009): 7398–411. http://dx.doi.org/10.3390/s90907398.

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21

Covarrubias-Zambrano, Obdulia, Massoud Motamedi, Bill T. Ameredes, Bing Tian, William J. Calhoun, Yingxin Zhao, Allan R. Brasier, et al. "Optical biosensing of markers of mucosal inflammation." Nanomedicine: Nanotechnology, Biology and Medicine 40 (February 2022): 102476. http://dx.doi.org/10.1016/j.nano.2021.102476.

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22

Rodríguez-Sevilla, P., L. Labrador-Páez, D. Jaque, and P. Haro-González. "Optical trapping for biosensing: materials and applications." Journal of Materials Chemistry B 5, no. 46 (2017): 9085–101. http://dx.doi.org/10.1039/c7tb01921a.

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Optical trapping has been evidence as a very powerful tool for the manipulation and study of biological entities. This review explains the main concepts regarding the use of optical trapping for biosensing, focusing its attention to those applications involving the manipulation of particles which are used as handles, force transducers and sensors.

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23

Buiculescu, Raluca, Dimitrios Stefanakis, Maria Androulidaki, Demetrios Ghanotakis, and Nikos A. Chaniotakis. "Controlling carbon nanodot fluorescence for optical biosensing." Analyst 141, no. 13 (2016): 4170–80. http://dx.doi.org/10.1039/c6an00783j.

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24

Zhang, Xi, Ying Guan, and Yongjun Zhang. "Ultrathin Hydrogel Films for Rapid Optical Biosensing." Biomacromolecules 13, no. 1 (December 14, 2011): 92–97. http://dx.doi.org/10.1021/bm2012696.

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25

Méjard, Régis, Hans J. Griesser, and Benjamin Thierry. "Optical biosensing for label-free cellular studies." TrAC Trends in Analytical Chemistry 53 (January 2014): 178–86. http://dx.doi.org/10.1016/j.trac.2013.08.012.

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26

Arroyo-Hernández, M., R. J. Martín-Palma, V. Torres-Costa, and J. M. Martínez Duart. "Porous silicon optical filters for biosensing applications." Journal of Non-Crystalline Solids 352, no. 23-25 (July 2006): 2457–60. http://dx.doi.org/10.1016/j.jnoncrysol.2006.02.075.

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27

Dorfner, D., T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley. "Photonic crystal nanostructures for optical biosensing applications." Biosensors and Bioelectronics 24, no. 12 (August 2009): 3688–92. http://dx.doi.org/10.1016/j.bios.2009.05.014.

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28

Nazmul Islam, Md, Sharda Yadav, Md Hakimul Haque, Ahmed Munaz, Farhadul Islam, Md Shahriar Al Hossain, Vinod Gopalan, Alfred K. Lam, Nam-Trung Nguyen, and Muhammad J. A. Shiddiky. "Optical biosensing strategies for DNA methylation analysis." Biosensors and Bioelectronics 92 (June 2017): 668–78. http://dx.doi.org/10.1016/j.bios.2016.10.034.

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29

Barrios, Carlos A., María José Bañuls, Victoria González-Pedro, Kristinn B. Gylfason, Benito Sánchez, Amadeu Griol, A. Maquieira, H. Sohlström, M. Holgado, and R. Casquel. "Label-free optical biosensing with slot-waveguides." Optics Letters 33, no. 7 (March 28, 2008): 708. http://dx.doi.org/10.1364/ol.33.000708.

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30

Azeemuddin, Syed. "Radio frequency biosensing and all-optical devices." CSI Transactions on ICT 8, no. 2 (June 2020): 137–46. http://dx.doi.org/10.1007/s40012-020-00294-4.

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31

Špringer, Tomáš, Xue Chadtová Song, Maria Laura Ermini, Josefína Lamačová, and Jiří Homola. "Functional gold nanoparticles for optical affinity biosensing." Analytical and Bioanalytical Chemistry 409, no. 16 (April 17, 2017): 4087–97. http://dx.doi.org/10.1007/s00216-017-0355-1.

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32

Tian, Yuanyuan, Lei Zhang, and Lianhui Wang. "DNA‐Functionalized Plasmonic Nanomaterials for Optical Biosensing." Biotechnology Journal 15, no. 1 (September 25, 2019): 1800741. http://dx.doi.org/10.1002/biot.201800741.

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33

Morales-Narváez, Eden, and Arben Merkoçi. "Graphene Oxide as an Optical Biosensing Platform." Advanced Materials 24, no. 25 (May 25, 2012): 3298–308. http://dx.doi.org/10.1002/adma.201200373.

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34

Zhou Xue, 周雪, 闫欣 Yan Xin, 张学楠 Zhang Xuenan, 王方 Wang Fang, 李曙光 Li Shuguang, 郎雷 Lang Lei та 程同蕾 Cheng Tonglei. "软玻璃光纤在生物传感领域应用的研究进展". Laser & Optoelectronics Progress 58, № 15 (2021): 1516019. http://dx.doi.org/10.3788/lop202158.1516019.

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35

Wu, Jiyun, and Qiuyao Wu. "The Review of Biosensor and its Application in the Diagnosis of COVID-19." E3S Web of Conferences 290 (2021): 03028. http://dx.doi.org/10.1051/e3sconf/202129003028.

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Анотація:

The objective of this article is to summarize the available technologies for biosensing applications in COVID-19. The article is divided into three parts, an introduction to biosensing technologies, applications of mainstream biosensing technologies and a review of biosensing applications in COVID-19. The introduction of biosensors presents the history of inventing the biosensing technology, which refers to the ISFET. The resonant biosensor with the example of MEMS. the principle of optical biosensor, and the thermal biosensor. In the second part, the main use of biosensing techniques, it was discussed the field of the food industry, environmental monitoring, and the medical industry. In the part of biosensor application in COVID-19, it was mentioned that the technique of POCT, the use of RT-LAMP-NBS in the early detection in China, and the use in gRT-PCR for the detection of the DNA code to determine the presence of pathogen of COVLD-19 in the human body.

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36

Lee, Sang-Nam, Jin-Ha Choi, Hyeon-Yeol Cho, and Jeong-Woo Choi. "Metallic Nanoparticle-Based Optical Cell Chip for Nondestructive Monitoring of Intra/Extracellular Signals." Pharmaceutics 12, no. 1 (January 7, 2020): 50. http://dx.doi.org/10.3390/pharmaceutics12010050.

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The biosensing platform is noteworthy for high sensitivity and precise detection of target analytes, which are related to the status of cells or specific diseases. The modification of the transducers with metallic nanoparticles (MNPs) has attracted attention owing to excellent features such as improved sensitivity and selectivity. Moreover, the incorporation of MNPs into biosensing systems may increase the speed and the capability of the biosensors. In this review, we introduce the current progress of the developed cell-based biosensors, cell chip, based on the unique physiochemical features of MNPs. Mainly, we focus on optical intra/extracellular biosensing methods, including fluorescence, localized surface plasmon resonance (LSPR), and surface-enhanced Raman spectroscopy (SERS) based on the coupling of MNPs. We believe that the topics discussed here are useful and able to provide a guideline in the development of new MNP-based cell chip platforms for pharmaceutical applications such as drug screening and toxicological tests in the near future.

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37

Giannetti, Ambra, and Sara Tombelli. "Aptamer optical switches: From biosensing to intracellular sensing." Sensors and Actuators Reports 3 (November 2021): 100030. http://dx.doi.org/10.1016/j.snr.2021.100030.

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38

Han, Yong Duk, Ka Ram Kim, Kyung Won Lee, and Hyun C. Yoon. "Retroreflection-based optical biosensing: From concept to applications." Biosensors and Bioelectronics 207 (July 2022): 114202. http://dx.doi.org/10.1016/j.bios.2022.114202.

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39

Baikova, Tatiana V., Pavel A. Danilov, Sergey A. Gonchukov, Valery M. Yermachenko, Andrey A. Ionin, Roman A. Khmelnitskii, Sergey I. Kudryashov, et al. "Diffraction microgratings as a novel optical biosensing platform." Laser Physics Letters 13, no. 7 (May 27, 2016): 075602. http://dx.doi.org/10.1088/1612-2011/13/7/075602.

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40

Wang, Yanan, Archana Kar, Andrew Paterson, Katerina Kourentzi, Han Le, Paul Ruchhoeft, Richard Willson, and Jiming Bao. "Transmissive Nanohole Arrays for Massively-Parallel Optical Biosensing." ACS Photonics 1, no. 3 (February 12, 2014): 241–45. http://dx.doi.org/10.1021/ph400111u.

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41

Emiliyanov, Grigoriy, Jesper B. Jensen, Ole Bang, Poul E. Hoiby, Lars H. Pedersen, Erik Michael Kjær, and Lars Lindvold. "Localized Biosensing with Topas Microstructured Polymer Optical Fiber." Optics and Photonics News 18, no. 12 (December 1, 2007): 19. http://dx.doi.org/10.1364/opn.18.12.000019.

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42

Gökay, U. S., M. Zakwan, and A. Serpengüzel. "Spherical silicon optical resonators: Possible applications to biosensing." European Physical Journal Special Topics 223, no. 10 (September 2014): 2003–8. http://dx.doi.org/10.1140/epjst/e2014-02243-6.

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43

Sansone, Lucia, Eleonora Macchia, Chiara Taddei, Luisa Torsi, and Michele Giordano. "Label-free optical biosensing at femtomolar detection limit." Sensors and Actuators B: Chemical 255 (February 2018): 1097–104. http://dx.doi.org/10.1016/j.snb.2017.08.059.

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44

Martı́n-Palma, R. J., V. Torres-Costa, M. Arroyo-Hernández, M. Manso, J. Pérez-Rigueiro, and J. M. Martı́nez-Duart. "Porous silicon multilayer stacks for optical biosensing applications." Microelectronics Journal 35, no. 1 (January 2004): 45–48. http://dx.doi.org/10.1016/s0026-2692(03)00216-7.

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45

Emiliyanov, Grigoriy, Jesper B. Jensen, Ole Bang, Poul E. Hoiby, Lars H. Pedersen, Erik M. Kjær, and Lars Lindvold. "Localized biosensing with Topas microstructured polymer optical fiber." Optics Letters 32, no. 5 (February 2, 2007): 460. http://dx.doi.org/10.1364/ol.32.000460.

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46

Ott, Johan R., Mikkel Heuck, Christian Agger, Per D. Rasmussen, and Ole Bang. "Label-free and selective nonlinear fiber-optical biosensing." Optics Express 16, no. 25 (December 2, 2008): 20834. http://dx.doi.org/10.1364/oe.16.020834.

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Gitsas, Antonis, Basit Yameen, Thomas Dominic Lazzara, Martin Steinhart, Hatice Duran, and Wolfgang Knoll. "Polycyanurate Nanorod Arrays for Optical-Waveguide-Based Biosensing." Nano Letters 10, no. 6 (June 9, 2010): 2173–77. http://dx.doi.org/10.1021/nl1009102.

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Sun, Yun-Lu, Si-Ming Sun, Pan Wang, Wen-Fei Dong, Lei Zhang, Bin-Bin Xu, Qi-Dai Chen, Li-Min Tong, and Hong-Bo Sun. "Customization of Protein Single Nanowires for Optical Biosensing." Small 11, no. 24 (March 18, 2015): 2869–76. http://dx.doi.org/10.1002/smll.201401737.

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49

Karabag, Aliekber, Dilek Soyler, Yasemin Arslan Udum, Levent Toppare, Gorkem Gunbas, and Saniye Soylemez. "Building Block Engineering toward Realizing High-Performance Electrochromic Materials and Glucose Biosensing Platform." Biosensors 13, no. 7 (June 25, 2023): 677. http://dx.doi.org/10.3390/bios13070677.

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Анотація:

The molecular engineering of conjugated systems has proven to be an effective method for understanding structure–property relationships toward the advancement of optoelectronic properties and biosensing characteristics. Herein, a series of three thieno[3,4-c]pyrrole-4,6-dione (TPD)-based conjugated monomers, modified with electron-rich selenophene, 3,4-ethylenedioxythiophene (EDOT), or both building blocks (Se-TPD, EDOT-TPD, and EDOT-Se-TPD), were synthesized using Stille cross-coupling and electrochemically polymerized, and their electrochromic properties and applications in a glucose biosensing platform were explored. The influence of structural modification on electrochemical, electronic, optical, and biosensing properties was systematically investigated. The results showed that the cyclic voltammograms of EDOT-containing materials displayed a high charge capacity over a wide range of scan rates representing a quick charge propagation, making them appropriate materials for high-performance supercapacitor devices. UV-Vis studies revealed that EDOT-based materials presented wide-range absorptions, and thus low optical band gaps. These two EDOT-modified materials also exhibited superior optical contrasts and fast switching times, and further displayed multi-color properties in their neutral and fully oxidized states, enabling them to be promising materials for constructing advanced electrochromic devices. In the context of biosensing applications, a selenophene-containing polymer showed markedly lower performance, specifically in signal intensity and stability, which was attributed to the improper localization of biomolecules on the polymer surface. Overall, we demonstrated that relatively small changes in the structure had a significant impact on both optoelectronic and biosensing properties for TPD-based donor–acceptor polymers.

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Portela, Alejandro, Olalla Calvo-Lozano, M. Carmen Estevez, Alfonso Medina Escuela, and Laura M. Lechuga. "Optical nanogap antennas as plasmonic biosensors for the detection of miRNA biomarkers." Journal of Materials Chemistry B 8, no. 19 (2020): 4310–17. http://dx.doi.org/10.1039/d0tb00307g.

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