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Статті в журналах з теми "Nucleic acid nanostructures"
Cutler, Joshua I., Ke Zhang, Dan Zheng, Evelyn Auyeung, Andrew E. Prigodich, and Chad A. Mirkin. "Polyvalent Nucleic Acid Nanostructures." Journal of the American Chemical Society 133, no. 24 (June 22, 2011): 9254–57. http://dx.doi.org/10.1021/ja203375n.
Повний текст джерелаZhang, Ke, Xiao Zhu, Fei Jia, Evelyn Auyeung, and Chad A. Mirkin. "Temperature-Activated Nucleic Acid Nanostructures." Journal of the American Chemical Society 135, no. 38 (September 16, 2013): 14102–5. http://dx.doi.org/10.1021/ja408465t.
Повний текст джерелаSeeman, Nadrian C. "Nucleic Acid Nanostructures and Topology." Angewandte Chemie International Edition 37, no. 23 (December 17, 1998): 3220–38. http://dx.doi.org/10.1002/(sici)1521-3773(19981217)37:23<3220::aid-anie3220>3.0.co;2-c.
Повний текст джерелаLi, Hanying, Thomas H. LaBean, and Kam W. Leong. "Nucleic acid-based nanoengineering: novel structures for biomedical applications." Interface Focus 1, no. 5 (June 28, 2011): 702–24. http://dx.doi.org/10.1098/rsfs.2011.0040.
Повний текст джерелаHan, Lin, Yuang Wang, Wantao Tang, Jianbing Liu, and Baoquan Ding. "Bioimaging Based on Nucleic Acid Nanostructures." Chemical Research in Chinese Universities 37, no. 4 (April 8, 2021): 823–28. http://dx.doi.org/10.1007/s40242-021-1055-0.
Повний текст джерелаSmith, David, Verena Schüller, Christian Engst, Joachim Rädler, and Tim Liedl. "Nucleic acid nanostructures for biomedical applications." Nanomedicine 8, no. 1 (January 2013): 105–21. http://dx.doi.org/10.2217/nnm.12.184.
Повний текст джерелаBechinger, Burkhard. "Peptide-nucleic acid nanostructures for transfection." BioMolecular Concepts 3, no. 3 (June 1, 2012): 283–93. http://dx.doi.org/10.1515/bmc-2011-0067.
Повний текст джерелаBellassai, Noemi, Roberta D’Agata, and Giuseppe Spoto. "Novel nucleic acid origami structures and conventional molecular beacon–based platforms: a comparison in biosensing applications." Analytical and Bioanalytical Chemistry 413, no. 24 (April 6, 2021): 6063–77. http://dx.doi.org/10.1007/s00216-021-03309-4.
Повний текст джерелаRichard Chandrasekaran, Arun. "Enhancing the biostability of nucleic acid nanostructures." Biophysical Journal 121, no. 3 (February 2022): 422a. http://dx.doi.org/10.1016/j.bpj.2021.11.667.
Повний текст джерелаTeller, Carsten, and Itamar Willner. "Functional nucleic acid nanostructures and DNA machines." Current Opinion in Biotechnology 21, no. 4 (August 2010): 376–91. http://dx.doi.org/10.1016/j.copbio.2010.06.001.
Повний текст джерелаДисертації з теми "Nucleic acid nanostructures"
Ong, Luvena Le-Yun. "Self-assembly of three-dimensional nucleic acid nanostructures." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106741.
Повний текст джерелаCataloged from PDF version of thesis.
Includes bibliographical references (pages 137-148).
Patterning complex 3D features at the nanoscale offers potential applications for a wide range of fields from materials to medicine. While numerous methods have been developed to manipulate nanoscale materials, these methods are typically limited by their difficulty in creating arbitrary 3D patterns. Self-assembly of nucleic acids has emerged as a promising method for addressing this challenge due to the predictability and programmability of the material and its structure. While a diversity of DNA nanostructures have been designed by specifying complementarity rules between strands, creation of 3D nanostructures requires careful design of strand architecture, and patterns are often limited to a volume of 25 x 25 x 25 nm³ Here, we address the challenges in structural DNA nanotechnology by developing a modular DNA "brick" approach. These bricks are short, single-stranded oliogomers that can self-assemble in a single-pot reaction to a prescribed 3D shape. Using this modular approach, we demonstrate high efficiency in 3D design by generating 100 distinct, discrete 3D structures from a library of strands. We also created long-range ordering of channels, tunnels, and pores by growing micron-sized 3D periodic crystals made from DNA bricks. Finally, we applied this approach to control over 30,000 unique component strands to selfassemble into cuboids measuring over 100 nm in each dimension. These structures were further used to pattern highly complex cavities. Together, this work represents a simple, modular, and versatile method for 3D nanofabrication. This unique patterning capability of DNA bricks may enable development of new applications by providing a foundation for intricate and complex control of an unprecedented number of independent components.
by Luvena Le-Yun Ong.
Ph. D. in Medical Engineering and Medical Physics
Sadowski, John Paul. "Design and synthesis of dynamically assembling DNA nanostructures." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:11272.
Повний текст джерелаChemistry and Chemical Biology
Chopra, Aradhana [Verfasser], Friedrich C. [Akademischer Betreuer] Simmel, Tim [Gutachter] Liedl, and Friedrich C. [Gutachter] Simmel. "Nucleic acid nanostructures: From biomimetic assembly to in vivo applications / Aradhana Chopra ; Gutachter: Tim Liedl, Friedrich C. Simmel ; Betreuer: Friedrich C. Simmel." München : Universitätsbibliothek der TU München, 2018. http://d-nb.info/117467153X/34.
Повний текст джерелаMitra, Debbie. "Novel synthesis of branched nucleic acids : towards applications in chemical biology and nanotechnology." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111880.
Повний текст джерелаChapter 2 delineates the regioselective template directed synthesis of Y-RNA via chemical ligation at the branch point of a 5'-phosphate to a 2'-hydroxyl. The branched molecules resemble lariats as they possess the analogous branched architecture. The oligonucleotide components are synthesized from commercially available phosphoramidite building blocks through automated solid-phase synthesis. A unique template directed method in the synthesis of DNA and RNA lariats is proposed in Chapter 3. The regioselective chemical ligation affords wild-type DNA and RNA formed through assembly of a single oligonucleotide strand. A parallel DNA:RNA hybrid association was observed in the preorganized assembly and extensively characterized. Characterization of the Y-RNA and lariat nucleic acids were carried out through techniques such as thermal denaturation analysis, polyacrylamide gel electrophoresis, enzymatic degradation with the RNA lariat debranching enzyme, alkaline treatment as well as MALDI-TOF mass spectrometry.
The second part of the thesis exploits DNA as a nanomaterial in the convergent solid-phase synthesis of Ru(II)-DNA conjugates as branched building blocks in the assembly of nanostructures. Chapter 4 describes the synthesis of Ru branched DNA, utilizing cis-[(bpy)2Ru(imidazole) 2]2+ moiety as the vertex tethered to parallel DNA covalently through flexible hexamethylene linkers. Complete physical characterization and preliminary hybridization studies are conducted. The Ru-DNA conjugates presented were found to be unstable to the protocols required for synthesis of mixed sequence derivatives. The stability and scope of synthesis of these molecules are further discussed.
As an alternative, Ru-DNA branched complexes of mixed sequences, exhibiting greater stability, were synthesized. The transition metal building blocks of Chapter 5 employ a more rigid branch point, linking two parallel DNA strands through a one methylene spacer to the cis-[Ru(bpy)2 (4,4'-bis(hydroxymethyl)-2,2'-bipyridine)][PF6]2 vertex. Physical characterization and the intrinsic luminescent properties of the transition metal complex were confirmed in both the Ru-branched DNA and hybrized forms. A comparative study of the self-assembly behavior of the Ru-DNA conjugates to that of unmetallated branched DNA was also conducted. Interestingly, results indicate a metal-mediated assembly of almost exclusive formation of one discrete Ru-DNA dimeric cyclic nanostructure, where as unmetallated DNA building blocks produced an array of products. Complete confirmation of these products is presented through PAGE and enzymatic digestions. Finally the synthesis of novel Delta and Λ Ru-branched DNA diastereomers is presented as potential building blocks in the creation of chiral metallo-supramolecular constructs.
Butler, Thomas. "Nanopore analysis of nucleic acids /." Thesis, Connect to this title online; UW restricted, 2007. http://hdl.handle.net/1773/9674.
Повний текст джерелаMohnani, Stefan. "Synthetic approaches towards modified peptide nucleic acids (PNAs) for biomimetical nanostructured surfaces." Doctoral thesis, Università degli studi di Trieste, 2011. http://hdl.handle.net/10077/4814.
Повний текст джерела“There is plenty of room at the bottom”. These were the famous words of Richard P. Feynman in 1959 that led to the birth of nanotechnology and nanoscience. Electronic devices based on inorganic semiconductors have been part of our daily lives for the last 60 years. Their miniaturisation has occurred gradually over the years, however, according to Moore’s law the contemporary microelectronic industry’s “top-down” manufacturing technique will soon reach its limits. Therefore, the recent development and increased knowledge of organic semiconductors has led to a tendency to explore alternative avenues with a focus on the creation of electronic devices based on organic molecules. The invention of techniques such STM (1981) and AFM (1986) have facilitated this research, allowing the imaging and manipulation of surfaces and molecules at the nanometre scale (0.1-100 nm). The next step is therefore the development of methods for the controlled fabrication of molecular assemblies and their integration into usable macroscopic systems. In this respect, the “bottom-up” approach offers considerable advantages over any other methodology (i.e. “top-down”) for the construction of nanoscale functional materials and devices. This approach generally exploits the hierarchical self-assembly of functional molecules through multiple non-covalent interactions to prepare long range ordered and defect-free assemblies barely accessible through conventional covalent synthesis. However, an intrinsic drawback of investigating such systems in solution or in a crystal is that molecular components cannot be directly addressed on a nanometric scale. As a consequence, the best engineering methodology involves modifying the surfaces of bulk materials such as metals or semiconductors by deposition of functional organic materials. The modified surfaces are then characterised using scanning probe microscopies (e.g. STM, AFM). To this end, surface-confined, supramolecularly constructed, bi-dimensional (2D) networks, featuring regular porous domains (controllable both in shape and size) are of particular significance in this research domain because their cavities can be used as receptors for the confinement of other remotely controlled functional molecules (e.g. molecular switches, luminescent chromophores). Since these complex nanostructures could ultimately find applications as optoelectronic devices, research efforts in this domain have been gathering momentum in recent years. In Chapter 1, the reader is introduced to the methods employed to construct porous networks on surfaces via supramolecular interactions. The second part of the chapter deals with recent examples of recognition, selection and immobilisation of guest molecules within the cavities of the networks, which is followed in the third part with a discussion about surface assemblies that display structural features or functionality in the third dimension. The last section of the chapter is devoted to the construction of porous networks on surfaces via the interactions of biomimetic molecules (e.g. DNA), which leads to the objectives of the present doctoral project. Inspired by the self-assembly of DNA into nanoporous arrays, it was postulated that the Watson-Crick base pairing of oligonucleotide’s nucleobases would be ideal in preparing 2D porous networks with large receptor cavities. The idea was to covalently attach complementary single stranded oligonucleotides to rigid angular and linear unit core modules respectively, and then allow the two units to self-assemble on surfaces. However, instead of using DNA oligonucleotides, the use of peptide nucleic acid (PNA) oligonucleotides was proposed since more robust architectures would be obtained due to the higher duplex stability displayed by this class of biomimetic molecules. This doctoral dissertation describes the synthetic steps taken towards achieving this goal. The design of the angular and linear units bearing complementary PNA oligomers, required for the preparation of self-assembled nanoporous arrays are described. However, prior to synthesizing these complex molecules, a simpler proof of principle was required to confirm that PNA duplexes could be formed on surfaces and also, whether the presence of chromophoric moieties (e.g. porphyrin) appended to the PNA strands had any effect on duplex formation and duplex stability. The molecule designed for this proof of principle was a self-complementary PNA dodecamer bearing a porphyrin adduct. The synthesis of the self-complementary PNA oligomer required for the preparation of the PNA-porphyrin adduct is described in the first part of Chapter 2. The main synthetic routes and protecting-group strategies used to prepare PNA monomers and oligomers are described first. This is followed by a discussion of the orthogonal protecting group strategies chosen for our project that would allow the isolation of PNA oligomers bearing protected nucleobases following resin-cleavage. This is contrary to the general norm in existing strategies wherein resin-cleavage and nucleobase deprotection is carried out in situ, however, it was required in our synthetic strategy since the terminal amino group of the PNA oligomers was required for further solution phase reactions. To this end, two protecting group strategies were proposed, a Fmoc/Mmt and Fmoc/Cbz-protecting group strategies. The solid support chosen for the Fmoc/Mmt strategy was Tentagel featuring a base-cleavable linker. Due to the failure to hydrolyse the linker during the resin-cleavage step, the Fmoc/Mmt strategy was abandoned. In the second strategy, an acid-cleavable Rink amide resin was chosen as the solid support, therefore a Fmoc/Cbz-protecting group strategy was chosen since it would allow the TFA-mediated cleavage of the oligomer from the resin, without the deprotection of the Cbz groups from the nucleobases. The preparation of the target PNA oligomer (sequence: TTAATTAATTAA) using the Fmoc/Cbz strategy is described in the next section. First, the required monomers for the oligomer synthesis were prepared using established procedures. Then, following reports of the advances in microwave assisted solid phase peptide synthesis claiming improved purity of oligomer products using short coupling times, the solid phase PNA oligomerisation was attempted using microwave irradiation. Three attempts were performed. The first, using a standard laboratory microwave, resulted in a complex mixture of products at the dodecamer stage. An improvement was observed in the results using the CEM discover SPS microwave which was specifically designed for solid phase synthesis, however, the crude dodecamer obtained was still inseparable from the by-products. Similar results were obtained with the CEM liberty microwave, which was an automated solid phase synthesis setup. Finally, utilising manual solid phase synthesis, the target PNA dodecamer was obtained. The HPLC chromatogram of crude PNA dodecamer obtained following resin cleavage displayed a single major product, which was subsequently purified. The oligomer was then deprotected by treatment with TMSI, and was analysed by mass spectrometry, which confirmed that the target dodecamer had been isolated. Section 2.2 described our efforts to prepare PNA-chromophore adducts. Following the isolation of the PNA dodecamer, attempts to covalently attach a porphyrin moiety to the resin-bound oligomer via an amide linkage failed, possibly due to steric hindrance. Subsequently, an azide linker was appended to the oligomer, and attempts to attach an acetylene functionalised porphyrin using a Cu(I)-catalysed 1,3-dipolar cycloaddition were performed. Unfortunately, this approach also did not yield the target adduct. These unsuccessful results paved the way to the development of a Cu(I)-free 1,3-dipolar cycloaddition that enabled the attachment of chromophores to the PNA oligomer. Recently published reports of Cu(I)-free 1,3-dipolar cycloaddition reactions applied on DNA oligomers offered inspiration towards this goal. The reported strategies involved the generation of a nitrile oxide species, which then reacted with either an alkene or an alkyne to form an isoxazoline or an isoxazole. Two methods of generating the nitrile oxide species were evaluated using anthracene derivatives. The first method involved the base-mediated dehydrochlorination of anthracene hydroximoyl chloride to yield the nitrile oxide, which then reacted with a dipolarophile that was introduced into the reaction mixture. The second approach to generating a nitrile oxide species involved treating an O-silylated hydroxamic acid derivative of anthracene with trifluoromethanesulfonic anhydride in the presence of a base (Carreira’s method). Following successful trapping of the nitrile oxides generated by both methods using trimethylsilyl ethylene as the dipolarophile, the reactions were applied on a resin-bound, acetylene-functionalised PNA dodecamer. Both methods yielded the target PNA-anthracene adduct. Since the nitrile oxide-acetylene 1,3-dipolar cycloaddition reaction had never been applied on porphyrins, a method had to be developed. Attempts to prepare a hydroximoyl chloride derivative of a porphyrin resulted in the decomposition of the macrocycle upon treatment with chlorinating agents (NCS, tert-BuOCl, and 1-chlorobenzotriazole), therefore, the hydroximoyl chloride method was abandoned in favour of the Carreira method. An O-silylated hydroxamic acid derivative of porphyrin was synthesized, and upon exposure to trifluoromethanesulfonic anhydride and Et3N, the nitrile oxide was generated and was trapped with a large excess (200 eq.) of trimethylsilyl ethylene yielding the target tetra-isoxazole porphyrin derivative in 62% yield, which corresponded to a yield of 89% per 1,3-dipolar cycloaddition. Optimisation of the reaction conditions using phenyl acetylene as the dipolarophile allowed similar yields to be obtained with only a 10 eq. excess of the acetylene. Having developed a protocol that was compatible with both PNA and porphyrin, the utility of the method to prepare a variety of PNA-chromophore adducts was tested. Hydroxamate derivatives of pyrene, porphyrin, phenanthroline and fluorescein chromophores were prepared. Subsequently, the corresponding nitrile oxide species were generated and were reacted with the resin-bound, acetylene-functionalised PNA dodecamer. The PNA-pyrene adduct was successfully isolated (Figure v), however, the other target PNA-chromophore products were not isolated. The porphyrin nitrile oxide derivative was insoluble in the reaction medium, thus preventing the cycloaddition reaction from proceeding. In the case of the fluorescein hydroxamate, the presence of nucleophilic functional groups in the starting material were probably reactive towards the trifluoromethanesulfonic anhydride reagent, therefore it was unlikely that the nitrile oxide species was formed, and thus the cycloaddition reaction could not proceed. Finally, the reaction with the phenanthroline derivative yielded a new product, however mass spectrometry analysis indicated that it did not correspond the target PNA-phenanthroline adduct. Further work is currently underway to re-evaluate these reactions. In parallel to the synthetic work, a preliminary study into the deposition of PNA onto mica surfaces was investigated using AFM imaging. Deposition of drops of an aqueous solution of deprotected self-complementary PNA dodecamer onto clean mica surfaces using spin coating resulted in aggregates of PNA on the surface. Following annealing of the solution, a repeated deposition of a single drop of the solution resulted in a completely different surface assembly. The surface was saturated by what was thought to be PNA duplexes. This was confirmed by the deposition of drop of a solution that was diluted ten-fold which resulted in an AFM image where bright spot were intermitted by clean mica surface. Topographical analysis of the surface indicated that the bright spots were an average in 1 nm in height, which closely corresponds to the expected height of PNA duplexes, thus confirming that PNA duplexes could be deposited onto surfaces.
XXII Ciclo
1981
STOPAR, ALEX. "Digital control of protein-nucleic acid interactions with self-assembled DNA nanosystems." Doctoral thesis, Università degli Studi di Trieste, 2016. http://hdl.handle.net/11368/2907995.
Повний текст джерелаOhtsuki, Shozo. "Elucidation and optimization of the interaction of nanostructured DNA and immune cells." Kyoto University, 2018. http://hdl.handle.net/2433/232322.
Повний текст джерелаSilva, Bruna Daniela Gonçalves da. "Nanopartículas lipídicas para a administração de produtos biofarmacêuticos." Master's thesis, [s.n.], 2015. http://hdl.handle.net/10284/5187.
Повний текст джерелаOs produtos biofarmacêuticos englobam os produtos à base de proteínas terapêuticas, de ácidos nucleicos e os que são usados em terapia celular. Com o crescimento exponencial que se tem verificado nos últimos anos para a biotecnologia farmacêutica, o uso clínico destes produtos tem vindo a aumentar. Contudo, tendo em conta as características físico-químicas das moléculas, têm surgido algumas limitações relativas à administração de produtos biofarmacêuticos. Com efeito, a investigação tem-se focado nos estudos relativos ao desenvolvimento de novos sistemas para veicular estes produtos. Neste contexto, e tendo em conta as vantagens que apresentam, as nanopartículas lipídicas têm sido apresentadas como promissoras. Na primeira parte deste trabalho é efectuada uma revisão bibliográfica relativa aos diferentes produtos biofarmacêuticos, às suas características e limitações de administração. Na segunda parte, é apresentada uma revisão relativa ao estado da arte do uso de nanopartículas lipídicas para promover a administração de produtos biofarmacêuticos. Biopharmaceutical products include therapeutic proteins, nucleic acids and cell-based products. Within the exponential growth of pharmaceutical biotechnology the clinical use of these products has been increasing. Nevertheless, according to the physical and chemical nature of the molecules, some limitations have appeared, limiting the use of biopharmaceutical products. In this way, the number of studies related with the development of new solutions for using biopharmaceutical products has been growing. Accordingly, due to its advantages, lipid nanoparticles have been presented as promising candidates. The first part of this work provides a bibliographic overview of the different biopharmaceutical products, and their characteristics and limitations for therapeutic use. In the second part, is presented a review of the state-of-the-art of using lipid nanoparticles systems to improve the therapeutic efficacy of biopharmaceutical products.
Bertucci, Alessandro. "Hybrid organic-inorganic interfaces for biomedical applications." Thesis, Strasbourg, 2015. http://www.theses.fr/2015STRAF008/document.
Повний текст джерелаThe research work presented throughout this thesis focuses on the development of novel organic-inorganichybrid materials for applications in nanotechnology, nanomedicine and diagnostics. In such a context, porous zeolite-L crystals have been used as nanocarriers to deliver either DNA or PNA in live cells, in combination with the release of guest molecules placed into the pores. Multifunctional mesoporous silica nanoparticles have been designed to treat glioblastoma, combining gene therapy with the sustained delivery of a chemotherapy agent. Biodegradable hybrid nano-shells have been furthermore created to encapsulate proteins and release them in living cells upon degradation of the outer structure in reductive environment. In the field of nucleic acid detection, photonic crystal fibers, functionalized with specific PNA probes, have been exploited as optical sensing devices to perform ultra-sensitive detection of DNA oligonucleotides or genomic DNA. Eventually, the PNA backbone has served as scaffold to synthesize fluorescent switching probes able to recognize and to detect the presence of specific target sequences
Книги з теми "Nucleic acid nanostructures"
V, Kumar Challa, ed. Novel enzyme/DNA/inorganic materials: A new generation of biomaterials. New York: Nova Science Publishers, 2008.
Знайти повний текст джерелаFang, Xiaohong, and Weihong Tan. Aptamers Selected by Cell-SELEX for Theranostics. Springer, 2015.
Знайти повний текст джерелаFang, Xiaohong, and Weihong Tan. Aptamers Selected by Cell-SELEX for Theranostics. Springer, 2015.
Знайти повний текст джерелаFang, Xiaohong, and Weihong Tan. Aptamers Selected by Cell-SELEX for Theranostics. Springer, 2016.
Знайти повний текст джерелаNarlikar, A. V., and Y. Y. Fu, eds. Oxford Handbook of Nanoscience and Technology. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533046.001.0001.
Повний текст джерелаЧастини книг з теми "Nucleic acid nanostructures"
Zhang, Douglas, and Thomas Hermann. "Metalated Nucleic Acid Nanostructures." In RNA Nanostructures, 97–103. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3417-2_5.
Повний текст джерелаTeter, Megan, Ross Brumett, Abigail Coffman, and Emil F. Khisamutdinov. "Thermodynamic Characterization of Nucleic Acid Nanoparticles Hybridization by UV Melting." In RNA Nanostructures, 151–61. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3417-2_9.
Повний текст джерелаAvila, Yelixza I., Laura Rebolledo, Melanie Andrade-Muñoz, and Kirill A. Afonin. "Characterization of PAMAM Dendrimers for the Delivery of Nucleic Acid Nanoparticles." In RNA Nanostructures, 253–59. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3417-2_17.
Повний текст джерелаByrnes, James, Kriti Chopra, Lewis A. Rolband, Leyla Danai, Shirish Chodankar, Lin Yang, and Kirill A. Afonin. "Structural Characterization of Nucleic Acid Nanoparticles Using SAXS and SAXS-Driven MD." In RNA Nanostructures, 65–94. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3417-2_4.
Повний текст джерелаHuq, Tamanna Binte, and Juan L. Vivero-Escoto. "Synthesis of Mesoporous Silica Nanoparticles for the Delivery of Nucleic Acid Nanostructures." In RNA Nanostructures, 205–10. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3417-2_13.
Повний текст джерелаGupta, Akhilesh Kumar, Joel Petersen, Elizabeth Skelly, Kirill A. Afonin, and Alexey V. Krasnoslobodtsev. "Small Volume Microrheology to Evaluate Viscoelastic Properties of Nucleic Acid-Based Supra-Assemblies." In RNA Nanostructures, 179–89. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3417-2_11.
Повний текст джерелаQuarles, Joshua D., Allen T. Livingston, Ashley E. Wood, and Timea Gerczei Fernandez. "Preparation of Nucleic Acid Aptamer Functionalized Silver/Gold Nanoparticle Conjugates Using Thiol-Substituted Oligonucleotides." In RNA Nanostructures, 131–47. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3417-2_8.
Повний текст джерелаTrammell, Susan R. "Light-Assisted Drying for the Thermal Stabilization of Nucleic Acid Nanoparticles and Other Biologics." In RNA Nanostructures, 117–30. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3417-2_7.
Повний текст джерелаde Freitas Saito, Renata, Bárbara Gomes Barion, Tania Rubia Flores da Rocha, Alex Rolband, Kirill A. Afonin, and Roger Chammas. "Anticoagulant Activity of Nucleic Acid Nanoparticles (NANPs) Assessed by Thrombin Generation Dynamics on a Fully Automated System." In RNA Nanostructures, 319–32. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3417-2_23.
Повний текст джерелаDai, Mingjie. "DNA-PAINT Super-Resolution Imaging for Nucleic Acid Nanostructures." In Methods in Molecular Biology, 185–202. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6454-3_13.
Повний текст джерелаТези доповідей конференцій з теми "Nucleic acid nanostructures"
Wagenknecht, Hans-Achim. "Functionalized DNA architectures: fluorophore assemblies and nanostructures." In XVth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2011. http://dx.doi.org/10.1135/css201112095.
Повний текст джерелаRabe, Kersten S., Udo Feldkamp, Christof M. Niemeyer, Wolfgang Fritzsche, and Frank Bier. "Semisynthetic DNA-protein conjugates for fabrication of nucleic acid based nanostructures." In DNA-BASED NANODEVICES: International Symposium on DNA-Based Nanodevices. AIP, 2008. http://dx.doi.org/10.1063/1.3012299.
Повний текст джерелаBier, Frank F., Ralph Hölzel, Wolfgang Fritzsche, and Frank Bier. "Nucleic Acid Based Nanostructures—Recent Advancements and the Impact of NUCAN." In DNA-BASED NANODEVICES: International Symposium on DNA-Based Nanodevices. AIP, 2008. http://dx.doi.org/10.1063/1.3012301.
Повний текст джерелаSwaminathan, Vikhram V., Spandana Gannavaram, Shihui Li, Huan Hu, Junghoon Yeom, Yong Wang, and Likun Zhu. "Microfluidic platform with hierarchical micro/nanostructures and SELEX nucleic acid aptamer coating for isolation of circulating tumor cells." In 2013 IEEE 13th International Conference on Nanotechnology (IEEE-NANO). IEEE, 2013. http://dx.doi.org/10.1109/nano.2013.6720968.
Повний текст джерелаBrown, Paige K., Ammar T. Qureshi, Daniel J. Hayes, and W. Todd Monroe. "Targeted Gene Silencing With Light and a Silver Nanoparticle Antisense Delivery System." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53647.
Повний текст джерелаZheng, Ming. "Manipulating Carbon Nanotubes with Nucleic Acids." In ELECTRIC PROPERTIES OF SYNTHETIC NANOSTRUCTURES: XVII International Winterschool/Euroconference on Electronic Properties of Novel Materials. AIP, 2004. http://dx.doi.org/10.1063/1.1812046.
Повний текст джерелаYeo, Woon-Hong, Jae-Hyun Chung, and Kyong-Hoon Lee. "Tuberculosis Diagnostics Using a Nanotip Sensor." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13065.
Повний текст джерелаKopacz, Adrian M., Wing K. Liu, and Jae-Hyun Chung. "Design and Optimization of a Nanotip Sensor via Immersed Molecular Electrokinetic Finite Element Method." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13299.
Повний текст джерелаNoguchi, Hiroki. "Heat Transfer Enhancement Effect of Nanostructured Surface Made of Carbon Nanotube on SiC Ceramics." In ASME 2013 11th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icnmm2013-73170.
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