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Готові списки джерел за темами / Novel Molecules / Книги

Книги з теми "Novel Molecules"

Щоб переглянути інші типи публікацій з цієї теми, перейдіть за посиланням: Novel Molecules.

Автор: Grafiati

Опубліковано: 10 грудня 2022

Оновлено: 28 січня 2023

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1

Modeling marvels: Computational anticipation of novel molecules. [Dordrecht]: Springer, 2008.

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2

Banik, Bimal K., ред. β-Lactams: Unique Structures of Distinction for Novel Molecules. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-33188-6.

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3

Ali, Sami Mohammed. Relaxation studies of various molecules using a novel modulated temperature technique. Salford: Universityof Salford, 1985.

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4

Molecular modeling for the design of novel performance chemicals and materials. Boca Raton: CRC Press, 2012.

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5

M, Blow D., Fersht Alan 1943-, Winter G, and Royal Society (Great Britain), eds. Design, construction, and properties of novel protein molecules: Proceedings of a Royal Society discussion meeting, held on 5 and 6 June 1985. London: Royal Society, 1986.

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6

Astrid, Gräslund, Rigler Rudolf, and Widengren Jerker, eds. Single molecule spectroscopy in chemistry, physics and biology: Nobel Symposium. Heidelburg [Germany]: Springer, 2010.

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7

Rudolf, Rigler, Orrit M. 1956-, and Basché T, eds. Single molecule spectroscopy: Nobel conference lectures. Berlin: Springer, 2001.

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8

Benfenati, Fabio, Enzo Di Fabrizio, and Vincent Torre, eds. Novel Approaches for Single Molecule Activation and Detection. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-43367-6.

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9

Pruzanski, Waldemar, and Peter Vadas, eds. Novel Molecular Approaches to Anti-Inflammatory Therapy. Basel: Birkhäuser Basel, 1995. http://dx.doi.org/10.1007/978-3-0348-7276-8.

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10

Treacher, Kevin Edward. Molecular and polymeric assemblies of novel substituted phthalocyanines. Manchester: University of Manchester, 1995.

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11

Dodziuk, Helena. Modern conformational analysis: Elucidating novel exciting molecular structures. New York: VCH, 1995.

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12

Bain, Lisa, Chanel Matney, and Clare Stroud, eds. Novel Molecular Targets for Mood Disorders and Psychosis. Washington, D.C.: National Academies Press, 2021. http://dx.doi.org/10.17226/26218.

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13

Pierce, Grant N., and William C. Claycomb, eds. Novel Methods in Molecular and Cellular Biochemistry of Muscle. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-6353-2.

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14

Schiavo, Cesare. The genesis of a novel class of interlocked molecular compounds. Birmingham: University of Birmingham, 1997.

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15

1947-, Rubanyi Gabor M., Dzau Victor J, and Cooke John P, eds. Vascular protection: Molecular mechanisms, novel therapeutic principles and clinical application. London: Taylor & Francis, 2002.

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16

Edward, Ziff, and Van Loon Borin 1951-, eds. DNA: A graphic guide to the molecule that shook the world. New York: Columbia University Press, 2011.

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17

Rosenfield, Israel. DNA: A graphic guide to the molecule that shook the world. New York: Columbia University Press, 2011.

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18

Lewars, Errol G. Modeling Marvels: Computational Anticipation of Novel Molecules. Lewars Errol G, 2010.

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19

Banik, Bimal K. β-Lactams: Unique Structures of Distinction for Novel Molecules. Springer London, Limited, 2012.

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20

Banik, Bimal K. β-Lactams: Unique Structures of Distinction for Novel Molecules. Springer, 2014.

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21

Banik, Bimal K. β-Lactams: Unique Structures of Distinction for Novel Molecules. Springer, 2012.

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22

Talevi, Alan, Guillermo Raul Castro, and Nelson Duran, eds. Lipid Nanoparticles as a Novel Strategy to Deliver Bioactive Molecules. Frontiers Media SA, 2021. http://dx.doi.org/10.3389/978-2-88966-697-3.

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23

Proietti, Silvia, Ivan Baccelli, Richard Hickman, Antonio Leon-Reyes, and Laura Bertini, eds. Novel Plant Molecules Regulating the Interaction with Pathogenic and Beneficial Fungi. Frontiers Media SA, 2021. http://dx.doi.org/10.3389/978-2-88966-568-6.

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24

Cowburn, David, Chaim Putterman, and Steven Almo. Structural Biology in Immunology: Structure/Function of Novel Molecules of Immunologic Importance. Elsevier Science & Technology Books, 2018.

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25

Weightman, John Spencer. Spectroscopic and electrochemical sensing of anions and cations using novel receptor molecules. 1996.

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26

Cowburn, David, Chaim Putterman, and Steven Almo. Structural Biology in Immunology: Structure/Function of Novel Molecules of Immunologic Importance. Elsevier Science & Technology Books, 2018.

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27

Maiese, Kenneth. Molecules to Medicine with MTOR: Translating Critical Pathways into Novel Therapeutic Strategies. Elsevier Science & Technology Books, 2016.

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28

Rai, Beena. Molecular Modeling for the Design of Novel Performance Chemicals and Materials. Taylor & Francis Group, 2012.

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29

Rai, Beena. Molecular Modeling for the Design of Novel Performance Chemicals and Materials. Taylor & Francis Group, 2012.

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30

Rai, Beena. Molecular Modeling for the Design of Novel Performance Chemicals and Materials. Taylor & Francis Group, 2019.

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31

Rai, Beena. Molecular Modeling for the Design of Novel Performance Chemicals and Materials. Taylor & Francis Group, 2012.

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32

Fragoulis, George E., and Iain B. McInnes. Small molecules in the treatment of psoriatic arthritis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198737582.003.0031.

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Анотація:

Psoriatic arthritis (PsA) is a chronic inflammatory arthritis, occurring in about one third of psoriasis patients, and exhibiting very varied clinical manifestations and comorbidities. Although the clinical outcome of the disease has been significantly improved recently, mainly due to utilization of novel agents targeting the IL-23/-17 axis, unmet needs still exist. Emerging insights into the disease’s pathogenesis led to development of new drugs acting against critical molecular targets and their efficacy in psoriasis and/or PsA has been tested in Phase III clinical trials. Some of these therapeutic regimens have been already approved; some look promising but others have been proven inefficacious. Future studies are expected to determine the place of these compounds within the therapeutic algorithm of PsA. In this chapter we describe the rationale and clinical impact of incorporating small molecules in PsA treatment, as well as specific molecules involved in pathogenesis that may serve as therapeutic targets.

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33

Acri, Jane B., and Phil Skolnick. Novel Approaches for Treating Addiction. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0048.

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Despite remarkable progress in our understanding of the neurobiological bases of drug abuse, no novel pharmacotherapies have recently been approved to treat substance use disorders (SUDs). Thus, while reformulations of established treatments have either been approved or are currently in late stage development (e.g., sustained release formulations of naltrexone (Vivitrol®) and buprenorphine), the development of medications to treat SUDs has lagged well behind other areas of psychiatry. In this chapter, we review some of the factors that have contributed to this dearth of innovative pharmacotherapies. We also review evidence that supports clinical testing of late stage molecules (developed for other indications) acting at promising targets, as well as novel biological approaches to the treatment of SUDs.

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34

Degen, Eric. Involvement of a novel molecular chaperone of the endoplasmic reticulm (p88/calnexin) in the biogenesis of class I histocompatibility molecules. 1995.

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35

Bensimon, David, Vincent Croquette, Jean-François Allemand, Xavier Michalet, and Terence Strick. Single-Molecule Studies of Nucleic Acids and Their Proteins. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198530923.001.0001.

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This book presents a comprehensive overview of the foundations of single-molecule studies, based on manipulation of the molecules and observation of these with fluorescent probes. It first discusses the forces present at the single-molecule scale, the methods to manipulate them, and their pros and cons. It goes on to present an introduction to single-molecule fluorescent studies based on a quantum description of absorption and emission of radiation due to Einstein. Various considerations in the study of single molecules are introduced (including signal to noise, non-radiative decay, triplet states, etc.) and some novel super-resolution methods are sketched. The elastic and dynamic properties of polymers, their relation to experiments on DNA and RNA, and the structural transitions observed in those molecules upon stretching, twisting, and unzipping are presented. The use of these single-molecule approaches for the investigation of DNA–protein interactions is highlighted via the study of DNA and RNA polymerases, helicases, and topoisomerases. Beyond the confirmation of expected mechanisms (e.g., the relaxation of DNA torsion by topoisomerases in quantized steps) and the discovery of unexpected ones (e.g., strand-switching by helicases, DNA scrunching by RNA polymerases, and chiral discrimination by bacterial topoII), these approaches have also fostered novel (third generation) sequencing technologies.

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36

W, Drew D. A novel MeV ion microbeam technique for measuring diffusion of small molecules in polymeric & biological matrices. 1996.

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37

Maiese, Kenneth. Molecules to Medicine with MTOR: Translating Critical Pathways of the Mammalian Target of Rapamycin into Novel Therapeutic Strategies. Elsevier Science & Technology Books, 2016.

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38

M, Blow D., Fersht Alan, Winter G, and Royal Society, eds. Design, construction and properties of novel protein molecules: A discussion organized and edited by D. M. Blow, A. R. Fersht, and G. Winter. London: The Royal Society, 1986.

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39

Haiduc, Ionel, and Edward RT Tiekink. Inverse Coordination Chemistry. Sunway University Press, 2020. http://dx.doi.org/10.55846/9789675492181.

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Анотація:

Inverse Coordination Chemistry: A Novel Chemical Concept presents the fascinating array of inverse coordination complexes, from monoatomic centres to those with organic molecules as centres, in a systematic manner with full-colour illustrative examples. This book is a timely and comprehensive introduction to this largely overlooked field of inverse coordination in inorganic chemistry.

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40

Tseng, Hua-an, Richie E. Kohman, and Xue Han. Optogenetics and Electrophysiology. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199939800.003.0009.

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Throughout the history of neuroscience, electrophysiological and imaging techniques have been utilized to observe neural signals at various spatial and temporal scales. However, it has been difficult to manipulate the activity of specific cells or neural circuits with the spatial and temporal resolutions relevant to neural coding. A novel technique called optogenetics, has recently been developed to control the activity of specific cells. This technique allows rapid and reversible optical activation or silencing of specific cells, which have been genetically transduced with light-sensitive molecules. The development of microbial opsin-based optogenetic molecular sensors has made optogenetics easily adaptable in various in vivo and in vitro preparations, and the technique has already been applied to understand neural circuit mechanisms of many behaviors and diseases. Here, we provide an introduction to optogenetics, the practical concerns in using the technique in vivo, and examples of applications that combine traditional electrophysiology techniques with optogenetics.

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41

Suffredini, Anthony F., and J. Perren Cobb. Genetic and molecular expression patterns in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0031.

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Investigators who study RNA, proteins, or metabolites use analytic platforms that simultaneously measure changes in the relative abundance of thousands of molecules in a single biological sample. Over the last decade, the application of these high-throughput, genome-wide platforms to study critical illness and injury has generated huge quantities of data that require specialized computational skills for analysis. These investigations hold promise for improving our understanding of the host response, thereby transforming the practice of intensive care. This chapter summarizes recent technological and computational approaches used in genomics, proteomics, and metabolomics. While major advances have been made with these approaches when applied to chronic diseases, the acute nature of critical illness and injury has unique challenges. The rapidity of initiating events, the trajectory of inflammation that follows injury or infection and the interplay of host responses to a replicating infection, all have major effects on changes in gene and molecular expression. This complexity is further accentuated by measurement that may vary with the timing and type of tissue sampled after the critical event. In addition, the hunt for novel molecular markers holds promise for identifying patients at risk for severe illness and for enabling more individualized therapy.

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42

Iversen, Leslie. Endocannabinoids. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190846848.003.0004.

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Анотація:

The endocannabinoids are part of a large family of lipid signaling molecules derived from arachidonic acid, including the prostaglandins and leukotrienes, which are important mediators of inflammation. Far less is known about the newer members of the endocannabinoid group, and it remains unclear whether they all play important functional roles. This chapter reviews the multiple members of this family and their biosynthesis and inactivation. Physiological functions, including retrograde synaptic signaling, control of energy metabolism, regulation of pain sensitivity, and cardiovascular control, are discussed. In addition, the chapter reports the synthesis of novel agonists, antagonists, and compounds inhibiting endocannabinoid inactivation as novel medicines.

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43

Teixeira, Antonio L., and Moises E. Bauer, eds. Immunopsychiatry. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190884468.001.0001.

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In recent years, great attention has been devoted to the understanding of the immune dysfunction that is associated with major psychiatric disorders. In the context of the reconceptualization of the immune system as a homeostatic system, immune cells, molecules and mechanisms are highly promising as new diagnostic and therapeutic targets to reduce the burden of mental/psychiatric disorders. In this regard, immune cells, molecules and mechanisms are highly promising. The literature on immunology of psychiatric disorders is still disperse, and only very few attempts have been done so far to consolidate the current knowledge in this expanding and exciting area. Each chapter will present the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential use of novel immunological biomarkers or therapeutic targets, as well as discussing the challenges ahead to incorporate this knowledge into the clinical practice.

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44

Molecule Man. Marvel Comics, 2010.

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45

H, Becker Kurt, ed. Novel aspects of electron-molecule collisions. Singapore: World Scientific, 1998.

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46

Becker, Kurt H. Novel Aspects of Electron-Molecule Collisions. WORLD SCIENTIFIC, 1998. http://dx.doi.org/10.1142/3790.

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47

Bouffard, Steven P. Novel applications of molecular microspectroscopy. 1994.

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48

Iversen, Leslie. The Pharmacology of Delta-9-Tetrahydrocannabinol (THC). Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190846848.003.0002.

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The 19th century was a great era for plant chemistry. Many complex drug molecules, known as alkaloids, were isolated and identified from plants. This chapter discusses the history of the discovery of delta-9-tetrahyrocannabinol (THC) as the psychoactive substance in cannabis products and also the discovery of the cannabinoid receptors CB-1 and CB-2 in the body and brain. The mechanism of action of cannabinoids on such receptors to inhibit neurotransmitter release or other actions is also discussed. In addition, various methods for the ingestion of cannabis, such as smoking and vaping, are reviewed. Synthetic agonists and antagonists at cannabinoid receptors and the proliferation of synthetic agonists as novel psychoactive agents are also discussed.

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49

Basche, T., R. Rigler, and M. Orrit. Single Molecule Spectroscopy: Nobel Conference Lectures. Springer London, Limited, 2012.

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50

Emsley, John. Molecules at an Exhibition. Oxford University Press, 1998. http://dx.doi.org/10.1093/oso/9780198502661.001.0001.

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Анотація:

What ingredient in Coke can remove rust from chrome? What is the bitterest substance on earth? What is the worst smelling one? In this entertaining tour of chemistry, John Emsley answers these and many other questions as he illuminates the materials that make up our world. Dozens of lively articles explore such well-known molecules as water, oxygen, and glass; versatile plastics like polypropylene, polystyrene, and polyurethane; even "elements from hell" such as Sarin (a lethal nerve gas). With no formulas, equations, or molecular diagrams to baffle the non-expert, each piece blends history, science, and anecdote, with many intriguing facts added to the mix. "The world of chemistry has never been made as entertaining," writes Nobel Prize-winning chemist Roald Hoffmann. Indeed, this book will fascinate everyone curious about the chemicals in the foods we eat, the clothes we wear, and the air we breathe.

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