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1

Wiggs, Robert B. "Bleaching nonvital teeth in canines." Journal of Veterinary Dentistry 6, no. 1 (March 1989): 9–13. http://dx.doi.org/10.1177/089875648900600105.

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2

Bersezio, C., P. Vildósola, M. Sáez, F. Sánchez, R. Vernal, OB Oliveira, G. Jorquera, J. Basualdo, A. Loguercio, and E. Fernández. "Does the Use of a “Walking Bleaching” Technique Increase Bone Resorption Markers?" Operative Dentistry 43, no. 3 (May 1, 2018): 250–60. http://dx.doi.org/10.2341/16-334-c.

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SUMMARY Objective: This randomized clinical trial evaluated the effect of 35% hydrogen peroxide in comparison with 37% carbamide peroxide in a nonvital bleaching technique of “walking bleaching” (four sessions of treatment) on periodontal markers: nuclear factor kappa B-ligand (RANK-L—process of root resorption marker) and interleukin 1β (IL-1β—inflammatory response marker). Methods and Materials: Fifty volunteers presenting with discoloration of nonvital teeth and endodontic treatment in good condition participated. Fifty teeth were randomly divided into two study groups according to bleaching gel: HP = 35% hydrogen peroxide (n=25) and 37% carbamide peroxide (n=25). Nonvital bleaching was performed with a walking bleaching technique consisting of four sessions of bleach application. Gingival crevicular fluid samples were taken in order to quantify the RANK-L and IL-1β levels by enzyme-linked immunosorbent assay. Samples were obtained from six periodontal sites for each bleached tooth: three vestibular and three palatine (mesial, middle, and distal) at seven time periods: baseline, after each of the four sessions of nonvital bleaching, at one week, and at one month after nonvital bleaching. Tooth color variations were analyzed in each session by VITA Bleachedguide 3D-MASTER (ΔSGU). Results: Significant increments in the RANK-L and IL-1β levels were detected in each evaluated time compared with baseline (p<0.05); however, no differences were detected between hydrogen peroxide and carbamide peroxide on increments of the biomarkers studied. The change of color was effective for both nonvital bleaching therapies (p<0.05). Conclusions: Nonvital bleaching induced a significant increment in the RANK-L and IL-1β levels in periodontal tissues around bleached, nonvital teeth.
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3

Feigin, Kristina, Cindy Bell, Bonnie Shope, Scott Henzel, and Christopher Snyder. "Analysis and Assessment of Pulp Vitality of 102 Intrinsically Stained Teeth in Dogs." Journal of Veterinary Dentistry 39, no. 1 (November 26, 2021): 21–33. http://dx.doi.org/10.1177/08987564211060387.

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Our prospective study analyzed clinical, radiographic, and histological characteristics of 102 intrinsically stained teeth. Sixty-nine dogs ranging from one to fifteen years of age were included in this study. Little more than half of the intrinsically stained teeth had no evidence of coronal injury (53.9%, 55/102). We found that most intrinsically stained teeth were histologically nonvital (87.6%, 85/97) and approximately 2/3 of these (57.7%, 56/97) had no histological endodontic or periodontal inflammation at the time of evaluation. Radiographic evidence of endodontic disease was present in 57% (58/102) of the intrinsically stained teeth. Radiographic evidence of periodontal disease was present in 48% (49/102) of intrinsically stained teeth and 28% (29/102) had radiographic evidence of tooth resorption. 18.6% (19/102) of intrinsically stained teeth were radiographically normal. Evidence of pulp necrosis was common in these intrinsically stained teeth, while only occasional teeth (12.4%, 12/97) had histologically confirmed pulpitis. All teeth with radiographic evidence of periapical lucency had pulp necrosis. Based on our histological findings, the majority of intrinsically stained teeth 87.6% are truly nonvital.
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4

VAN DANA, K. V. "PERIODONTAL REGENERATION IN NONVITAL TEETH - A REVIEW." CODS Journal of Dentistry 2, no. 1 (2010): 14. http://dx.doi.org/10.5005/cods-2-1-14.

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5

Bersezio, C., J. Martin, F. Peña, M. Rubio, J. Estay, R. Vernal, OB Oliveira Junior, and E. Fernández. "Effectiveness and Impact of the Walking Bleach Technique on Esthetic Self-perception and Psychosocial Factors: A Randomized Double-blind Clinical Trial." Operative Dentistry 42, no. 6 (November 1, 2017): 596–605. http://dx.doi.org/10.2341/16-133-c.

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SUMMARY Objective: This trial evaluates the impact of psychosocial and esthetic self-perceptions of patients undergoing nonvital tooth bleaching using the walking bleach technique. We also assessed the clinical effectiveness of bleaching tooth discoloration. Methods: Fifty volunteers with nonvital tooth discoloration were enrolled. Teeth were randomized into two groups: 35% hydrogen peroxide (n=25) and 37% carbamide peroxide (n=25). Intracoronal bleaching was performed over four sessions using the walking bleach technique. Tooth color was evaluated at each session to measure total color variation. The shade guide was arranged from highest (B1) to lowest (C4) values to assess the color and calculate the color change in the number of shade guide units. Subjective and objective assessments were compared with the tooth counterpart. Esthetic self-perception and psychosocial factors were assessed before and after treatment. Results: Color change was 15.48<5.17 for hydrogen peroxide and 14.02<4.85 for carbamide peroxide. There was no significant difference at any time point (p>0.05) except at sessions 3 and 4 (p<0.05). Overall, whitened teeth values were similar to those of counterpart teeth (p>0.05). There was a decrease in Oral Health Impact Profile and Psychosocial Impact of Dental Esthetics questionnaire scores after treatment compared with baseline (p<0.05). Conclusion: The walking bleach technique was highly effective on nonvital teeth and had a positive effect on self-esthetic perception and psychological impact for the patients.
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6

Kaur, Avninder, Anchal Soni, and Harees Shabir. "Single Sitting Revitalization of Nonvital Young Permanent Teeth." Dental Journal of Advance Studies 8, no. 03 (September 1, 2020): 127–30. http://dx.doi.org/10.1055/s-0040-1714157.

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AbstractA 9-year-old child reported with chief complaint of broken teeth (11 and 21) and discolored tooth (21). Diagnosis of pulp necrosis with apical periodontitis with regard to 11 and 21 was made based on clinical and radiographic examination. The canals were irrigated with sodium hypochlorite and then dried with paper points. Disinfection of canals was done using photoactivated disinfection (PAD). Platelet-rich fibrin (PRF) was placed as scaffold in canals till the cementoenamel junction (CEJ). A 2-mm thick layer of white MTA was placed, followed by dual seal using glass–ionomer cement (GIC) and composite resin. Follow-up examination was done for 1 year. Clinical examination showed no pain, tenderness on percussion, and no mobility and improvement in color of teeth. Radiographic evaluation revealed continued thickening of the dentinal walls, root lengthening, regression of the periapical lesion, and partial apical closure. This report of pulp revascularization shows that disinfection with photodynamic therapy combined with PRF resulted in satisfactory root development in necrotic immature teeth.
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7

Zacher, Amalia, and Sandra Manfra Marretta. "Decision-Making and Management of Immature Permanent Teeth with Crown Fractures in Small Animals—A Review." Journal of Veterinary Dentistry 38, no. 2 (June 2021): 81–92. http://dx.doi.org/10.1177/08987564211046325.

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Immature permanent teeth with crown fractures present a unique challenge in human and animal patients. Immature permanent teeth have not yet developed completely, often presenting with thin dentin walls, incomplete apical formation, and increased crown-to-root ratios. Loss of pulp function at this stage has devastating long-term implications for these teeth. Ideally, attempts should be made to preserve pulp vitality in immature permanent teeth to allow for continued dental development. The range of treatment options for vital teeth includes odontoplasty with bonding and sealing +/− restoration, indirect pulp capping, and direct pulp capping/vital pulp therapy. These treatments have long been established in human and veterinary medicine, and cases have been reported in dogs and cats. Apexification using calcium hydroxide is a well-established treatment for nonvital immature teeth. The advent of mineral trioxide aggregate and other bioceramic materials for use in vital pulp therapy and apexification has reduced treatment sessions and improved outcomes. Recent developments in the field of regenerative endodontic therapy further expand treatment options and provide the possibility for continued development of a formerly nonvital tooth. Selecting the appropriate treatment based on the severity of tooth fracture and status of pulp vitality can avoid a lifetime of poor structure and function for the affected tooth. This article provides multiple step-by-step protocols for the management of immature permanent teeth with crown fractures in small animals.
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8

da Cunha, Leonardo Fernandes, José Mondelli, Caroline Moreira Auersvald, Carla Castiglia Gonzaga, Rafael Francisco Lia Mondelli, Gisele Maria Correr, and Adilson Yoshio Furuse. "Endocrown with Leucite-Reinforced Ceramic: Case of Restoration of Endodontically Treated Teeth." Case Reports in Dentistry 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/750313.

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A common problem encountered by dentists is the restorative treatment of nonvital teeth. When the pulp chamber presents appropriate conditions for retention, the endocrown is indicated. This monolithic, ceramic adhesive restoration is singularly used yet warrants wider recognition and use. The endocrown allows preservation of the tooth structure and is minimally invasive. Currently, this treatment option, of a core buildup and full coverage restoration, reduces tooth structure excessively. This treatment presents not only functional limitations but also aesthetic concerns. Recently, the VITA-PM9 system, a leucite-reinforced glass ceramic, has been increasingly used in a variety of clinical situations due to its satisfactory physical-mechanical and aesthetic properties. Therefore, the present study describes a case of surgical restoration of a nonvital tooth using the endocrown technique and the VITA-PM9.
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9

Bolli, Rashmi V., and Aanchal M. Agrawal. "Management of Traumatized Open Apex Teeth with Mineral Trioxide Aggregate Apexification and Demineralized Freeze-dried Bone Allograft as Apical Matrix." Journal of Contemporary Dentistry 6, no. 3 (2016): 194–99. http://dx.doi.org/10.5005/jp-journals-10031-1171.

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ABSTRACT Achievement of a perfect apical seal in the case of a traumatized nonvital open apex tooth is one of the most important factors affecting its long-term success. It can be treated surgically by placing a retrofill or by a nonsurgical approach by apexification. Currently, apexification with mineral trioxide aggregate (MTA) is the treatment of choice in such cases. Herein, due to large apical diameter, limiting the MTA within the canal space is challenging, making it imperative to use a suitable apical matrix. This case report demonstrates successful management of traumatized nonvital open apex teeth with MTA apexification using demineralized freeze-dried bone allograft apical matrix. How to cite this article Bolli RV, Sumanthini MV, Shenoy VU, Agrawal AM. Management of Traumatized Open Apex Teeth with Mineral Trioxide Aggregate Apexification and Demineralized Freeze-dried Bone Allograft as Apical Matrix. J Contemp Dent 2016;6(3):194-199.
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10

Hossain, Md Ismail, Md Nahid Khurram Choudhury, Md Shamsul Alam, Shahnaz Sultana Beauty, and Farid Uddin. "Evaluation of LSTR 3 Mix MP Therapy for Healing of Periapical Pathosis of Nonvital Teeth." TAJ: Journal of Teachers Association 33, no. 2 (December 31, 2020): 76–84. http://dx.doi.org/10.3329/taj.v33i2.51343.

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Context: LSTR 3 Mix MP therapy is one of the procedures for the management of nonvital tooth with periapical lesion. The principle of this therapy is the complete sterilization of the total pulp canal space, thereby healing of the periradicular lesion. Objectives: To assess the clinical and radiological outcome of ‘Lesion sterilization and Tissue Repair’ (LSTR) for endodontic treatment of nonvital teeth with periapical lesion. Materials and Methods: This descriptive, observational study allocated 40 nonvital teeth with periapical lesion treated by LSTR 3 Mix MP Therapy. In study subjects, a mixture of Metronidazole, Ciprofloxacin and Minocycline (3 Mix) in a proportion of 1:1:1 in ointment (Macrogol mixed with propylene glycol: MP) was placed at the orifice of the root canal or the bottom of pulp chamber after gaining access in the pulp chamber and removal of necrotic pulp, then sealed with Glass Ionomer cement and further reinforced by composite resin. The protocols for follow up examination were 3, 6 and 12 months post operatively. At the time of follow up examination a standard follow up chart was maintained. Results: Out of 40 cases, in 29 cases had good responses both clinically and radiologically and 8 patients came back with some complications. Out of these 8 patients, 6 patients had uncertain outcome and in 2 patients it was unacceptable. Conclusion: LSTR 3 mix MP therapy reduced clinical signs and symptoms successfully in teeth with periapical lesion and radiological improvement of the periapical index was also noted. TAJ 2020; 33(2): 76-84
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11

SETTEMBRINI, LEONARD, JERROLD GULTZ, JAMES KAIM, and WARREN SCHERER. "A TECHNIQUE FOR BLEACHING NONVITAL TEETH: INSIDE/OUTSIDE BLEACHING." Journal of the American Dental Association 128, no. 9 (September 1997): 1283–84. http://dx.doi.org/10.14219/jada.archive.1997.0406.

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12

Yanikian, CRF, F. Yanikian, D. Sundfeld, RBE Lins, and LRM Martins. "Direct Composite Resin Veneers in Nonvital Teeth: A Still Viable Alternative to Mask Dark Substrates." Operative Dentistry 44, no. 4 (July 1, 2019): E159—E166. http://dx.doi.org/10.2341/18-220-t.

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SUMMARY Direct composite resin veneers are a practical esthetic restorative treatment for reestablishing the shape and color of affected anterior teeth. The present clinical case reports aim to describe restorative treatment techniques for nonvital anterior teeth presenting color alteration. The direct composite resin layering technique has proven to be an efficient method for recovering the esthetics of darkened teeth. The direct vs indirect restorative treatments are debated as well. Clinical follow-ups of the presented case reports demonstrate that direct composite resin restorations are not affected by the darkened tooth substrate over time.
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13

Lata, Prem, Ajay Chhabra, Varun Jindal, and Arun Thakur. "In–Vivo Clinical Evaluation of Regenerative Endodontics in Immature Necrotic Permanent Teeth With Open Apex." Dental Journal of Advance Studies 03, no. 01 (April 2015): 026–33. http://dx.doi.org/10.1055/s-0038-1672010.

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Abstract Introduction: This study was conducted to evaluate clinical and radiographic findings induced by revascularization with and without platelet-rich plasma (PRP). Methods: Twenty patients with nonvital, immature anterior teeth were randomly categorized into 2 groups. Subsequent to minimal instrumentation of the root canal, disinfection was achieved with ledermix paste and followed by revascularization with and without PRP in groups 1 and 2, respectively. The cases were followed up clinically and radiographically at 6- and 12-month intervals. Results: Clinically, all cases were asymptomatic with complete resolution of signs and symptoms (except four cases which were considered as dropout). Radiographically, there was no significant difference in periapical healing, apical closure, and dentinal wall thickening in group I in comparison with group II. However, root lengthening was comparable for both of the procedures. Conclusions: Revascularization is a conservative and an effective method for inducing maturogenesis in nonvital, immature teeth. Supplementations with PRP can potentially improve the desired biological outcome of this regenerative procedure.
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14

Bersezio, C., P. Ledezma, J. Estay, C. Mayer, O. Rivera, and E. Fernández. "Color Regression and Maintenance Effect of Intracoronal Whitening on the Quality of Life: RCT—A One-year Follow-up Study." Operative Dentistry 44, no. 1 (January 1, 2019): 24–33. http://dx.doi.org/10.2341/17-288-c.

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SUMMARY Objective: This randomized clinical study evaluated two parameters: 1) the clinical color rebound of whitening patients' tooth discoloration using the walking bleaching technique and 2) the impact on psychological and aesthetic self-perception at the one-year follow-up of patients who underwent bleaching of nonvital teeth. Methods and Materials: Fifty study participants with nonvital tooth discoloration were recruited. Teeth were assigned randomly into one of two groups: 1) 35% hydrogen peroxide (n=25) and 2) 37% carbamide peroxide (n=25). Intracoronal bleaching was carried out over the course of four sessions using the walking bleach technique. Tooth color was evaluated after each session in order to measure the total color variation (ΔE). The guide was arranged from highest (B1) to lowest values (C4) for evaluating color, and color changes using Vita Classical Shade (ΔSGUs) units were calculated. Subjective and objective assessments were compared with the counterpart of the tooth. Aesthetic perception and psychosocial factors were evaluated before and after treatment by the Oral Health Impact Profile (OHIP) and Psychological Impact of Dental Impact Questionnaire (PIDAQ) surveys. Results: Color changes (ΔE) were 15.48 ± 5.17 and 14.02 ± 4.85 for carbamide and hydrogen peroxide groups, respectively. There were no significant differences (p>0.05) between these two groups at the one-year follow-up. There was a decrease in the PIDAQ scores after treatment compared to baseline values (p<0.05). The majority of OHIP values regressed to baseline values. Conclusion: The technique of walking bleaching was highly effective and showed minimal color rebound in nonvital teeth and had a positive effect on patients' psychological impact at the one-year follow-up.
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15

BIÇAKCI, Hasan, Ömer ZENCİRLİ, Fatma CEBE, and Mehmet Ata CEBE. "Bleaching Discoloured Nonvital Teeth Using Walking Bleaching Technique: Case Report." Turkiye Klinikleri Journal of Dental Sciences Cases 1, no. 4 (2015): 290–96. http://dx.doi.org/10.5336/dentalcase.2015-48448.

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16

Park, Sun-Ah, Sun-Ho Kim, Yun-Chan Hwang, Byung-Ju Oh, Chang Youn, Yeong-Joon Park, Sun-Wa Jeong, In-Nam Hwang, and Won-Mann Oh. "Bleaching effect of carbamide peroxide gel on discolored nonvital teeth." Journal of Korean Academy of Conservative Dentistry 27, no. 4 (2002): 441. http://dx.doi.org/10.5395/jkacd.2002.27.4.441.

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17

Etman, Ahmed, Ibrahim ElKalla, Salwa Awad, and Hanaa Mahmoud. "Revascularization Procedures in nonvital Immature Permanent Teeth a Comparative Study." Delta University Scientific Journal 5, no. 2 (December 1, 2022): 43–52. http://dx.doi.org/10.21608/dusj.2022.275421.

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18

Claudia, García-Guerrero, Mora-Pinza Tania, Quijano-Guauque Sara, Leal-Fernández Carolina, and Baldión-Elorza Paula. "Clinical, Histological, and Molecular Perspective on Regenerating Nonvital Immature Teeth." Contemporary Clinical Dentistry 14, no. 3 (2023): 220–26. http://dx.doi.org/10.4103/ccd.ccd_44_23.

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Abstract Background: Disinfection and dentin conditioning promote a favorable scenario for regenerative endodontic treatment. Clinical reports have confirmed periapical normality with high variability in disinfection protocols; nevertheless, the nature of neoformed tissue varied between them. Thus, this study aimed to present the impact of disinfection protocols on the clinical, histological, and molecular outcomes of regenerative endodontics procedures in permanent teeth with incomplete root formation. Materials and Methods: Eighteen teeth with incomplete root formation which required endodontic regenerative treatment were treated with different disinfection and conditioning agents and followed under clinical control. One case was evaluated under histological and immunohistochemical analyses. Results: Clinical outcomes revealed periapical repair in 17/18 cases. Histological and immunohistochemical analyses confirmed the neoformation of the dentinal matrix and its mineralization. Conclusions: Chemical conditioning could impact the outcome of regenerative endodontic procedures. The histological and immunohistochemical analysis showed the nature of the newly formed tissue that correlates with the clinical outcome.
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19

Demarco, Flávio Fernando, Marcus Cristian Muniz Conde, Caroline Ely, Eliana Nascimento Torre, José Ricardo Souza Costa, María Raquel Fernández, and Sandra Beatriz Chaves Tarquinio. "Preferences on Vital and Nonvital Tooth Bleaching: A Survey Among Dentists from a City of Southern Brazil." Brazilian Dental Journal 24, no. 5 (October 2013): 527–31. http://dx.doi.org/10.1590/0103-6440201302152.

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This study evaluated the preferences of general dentists regarding vital and nonvital tooth bleaching therapies and investigated whether the time of clinical practice and post-graduate training influence these options. A cross-sectional study was conducted using a questionnaire with closed questions applied to dentists (n=276) of a mid-sized city of the southern Brazil (Pelotas, RS). Information was collected regarding sociodemographic variables, level of specialization and time since graduation. In addition, options regarding bleaching therapies including the first choice of material, technique and clinical practice for vital and nonvital tooth bleaching therapies were included. Data were submitted to descriptive analysis and the associations were evaluated using chi-square and Fisher exact tests (α=0.05). The response rate was 68% (n=187). At-home bleaching therapy was broadly preferred (78.1%) over in-office (21.9%) bleaching. For at-home bleaching, most dentists answered to use 10% carbamide peroxide (CP) (40.2%) and >30% hydrogen peroxide (HP) (31.7%) for nonvital therapies. The majority of dentists with post-graduation training preferred at-home bleaching techniques (p=0.003). At-home bleaching therapy was also more indicated by younger dentists. No association was found between the choice for nonvital bleaching therapies and time since graduation (p=0.532) or continuous education (p=0.083). In conclusion, at-home bleaching was preferred over in-office therapies; 10% CP and >30% HP were chosen as first option agents to treat discolored vital and nonvital teeth, respectively. The time in clinical practice and the level of specialization affected dentists' choices only for vital tooth bleaching treatment.
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20

Hossain, Md Ismail, Monira Parveen, Md Nahid Khurram Choudhury, Tasnim Wakia, Farid Uddin, and Md Shoyeb Rahman. "Evaluation of Conventional Root Canal Treatment for Healing of Periapical Pathosis of Nonvital Teeth." TAJ: Journal of Teachers Association 33, no. 1 (October 18, 2020): 25–30. http://dx.doi.org/10.3329/taj.v33i1.49821.

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Background: Root canal Therapy is one of the procedures for the management of nonvital tooth with periapical lesion. The principle of this therapy is the complete sterilization of the total pulp canal space thereby healing of the periradicular lesion. Objectives: This experimental study assessed the clinical and radiological outcome of root canal treatment for nonsurgical management of nonvital teeth with periapical lesion. Materials and Methods: A total number of 40 infected teeth with periapical lesion were treated by conventional root canal treatment. Irritants from the root canal system was removed by mechanical instrumentation( Crown down Technique), chemical irrigation with NaOCL and by using Calcium Hydroxide as intracanal medicaments and fluid tight obturation both apically and coronally resulting repairs of inflamed periradicular tissues. The protocol for follow up examination will be 3, 6 and 12 months post operatively. At the time of follow up examination a standard follow up chart will be maintained. Results: Among 40 cases 32 cases could be treated as acceptable as their responses were good both clinically and radiologically and 5 patients came back with some complications among them 3 cases were uncertain and 2 cases were unacceptable. Conclusion: It was concluded that conventional root canal treatment reduced clinical signs and symptoms successfully in teeth with periapical lesion and radiologically. TAJ 2020; 33(1): 25-30
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21

Tandon, Shobha, and N. Sridhar. "Continued Root-End Growth and Apexification Using a Calcium Hydroxide and Iodoform Paste (Metapex®): Three Case Reports." Journal of Contemporary Dental Practice 11, no. 5 (2010): 63–70. http://dx.doi.org/10.5005/jcdp-11-5-63.

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Abstract Aim The aim of these case reports is to present a treatment to promote root-end growth and apexification in nonvital immature permanent teeth in children. Methods and Materials Three cases were presented where the calcium hydroxide and iodoform paste Metapex® was placed in the root canals of immature permanent teeth using disposable plastic tips. The teeth involved were evaluated radiographically at regular intervals for the first 12 months after placement of the paste. At the end of 12 months all the cases showed continued root growth and apical closure (apexification) with no evidence of periapical pathology. Conventional endodontic treatment was then performed. Results In all three of the clinical cases presented, a combination of calcium hydroxide and iodoform paste (Metapex®) was used and showed promising results in inducing root-end growth and closure after 12 months. Conclusion In these three clinical cases, the calcium hydroxide and iodoform paste Metapex® (Meta Biomed Co. Ltd., South Korea) was found to induce apical closure when assessed radiographically. Over a period of 12 months all the cases showed continued root growth. Clinical Significance The calcium hydroxide and iodoform paste Metapex® promoted continued root-end growth with apexification in the nonvital immature permanent teeth treated. Citation Sridhar N, Tandon S. Continued Root-Growth and Apexification Using a Calcium Hydroxide and Iodoform Paste (Metapex®): Three Case Reports. J Contemp Dent Pract [Internet]. 2010 October; 11(5):063-070. Available from: http://www.thejcdp.com/journal/view/volume11- issue5-sridhar
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22

Munshi, A., Amitha Hegde, and Sangeeth Radhakrishnan. "Pulse oximetry: a diagnostic instrument in pulpal vitality testing." Journal of Clinical Pediatric Dentistry 26, no. 2 (January 1, 2003): 141–45. http://dx.doi.org/10.17796/jcpd.26.2.2j25008jg6u86236.

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One hundred children with normal maxillary central and lateral incisors were subjected to vitality tests each by electrical and pulse oximetry. As a control population to confirm the readings, 10 known nonvital anterior teeth with complete endodontic fillings were tested. The systemic oxygen saturation values measured on the index finger of the patient served as the control for the comparison of the oxygen saturation values measure on the teeth. The SaO2 values obtained on the teeth were correlated with the electrical test readings. The correlation between the SaO2 readings and electrical testing readings were found to be negative i.e. as the values of the electrical pulp testing reading increased, the SaO2 values decreased. Since a reproducible SaO2 level is obtainable on the vital teeth, pulse oximetry has immediate clinical value in providing base line vitality data for the traumatised teeth.
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23

Patel, Suhag, Salwa Zafar, Abhishek Singh, Neetika Jain, and Ronak Choudhary. "A revitalization protocol lead to different outcomes in adjacent teeth." Journal of Research in Dentistry 3, no. 5 (March 21, 2016): 808. http://dx.doi.org/10.19177/jrd.v3e52015808-813.

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Regenerative Endodontic Procedures can be defined as biologically based procedures designed to replace damaged structures including dentin and cells of the pulp – dentin complex. The term revascularization is more commonly employed with regenerative procedures and describes reintroduction of vasculature in the root canal system. This case report describes the treatment of two nonvital immature teeth with infected pulp. Revitalization was attempted in two adjacent teeth by the same operator following similar protocol. In one of the teeth, revitalization was successful with continued root wall thickening, root lengthening and closure of the apex whereas in the adjacent tooth though root lengthening could not be achieved, a definite apical closure with irregular root wall thickening could be obtained.
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Ibrahim Mostafa, Mostafa, Nehad Samir Taha, and Mennat Allah Ismail Mehrez. "Generalised versus Regional Odontodysplasia: Diagnosis, Transitional Management, and Long-Term Followup—A Report of 2 Cases." Case Reports in Dentistry 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/519704.

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Background. Odontodysplasia is an uncommon condition. It can be localised or generalised, isolated or part of a syndrome.Case Report. We first report the case of an 8.5-year-old boy who presented with abnormally shaped teeth and multiple intraoral abscesses. Findings of clinical and radiographic examinations were consistent with those of generalised odontodysplasia. A 2-step, conservative treatment plan was executed with a 10-year followup. Step 1 was root canal treatment of nonvital teeth. Step 2 was crowning without preparation of new vital, erupted, and malformed teeth. The second case is that of a 12-year-old girl who presented with lack of teeth in the upper-left quadrant. The impacted teeth were exposed surgically, and fixed restoration was performed for temporary aesthetic improvement.Conclusion. Instead of tooth extraction, an approach previously used in similar cases, conservative management is feasible and offers better prosthetic treatment options for the future.
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Bora, Amitava, Shabnam Zahir, GautamKumar Kundu, and Abhirup Goswami. "Regenerative pulp therapy for immature nonvital teeth with plasma-rich fibrin." SRM Journal of Research in Dental Sciences 6, no. 3 (2015): 198. http://dx.doi.org/10.4103/0976-433x.162184.

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26

Rodrigues, Homero Habel, and Joao Carlos Gabrielli Biffi. "A histobacteriological assessment of nonvital teeth after ultrasonic root canal instrumentation." Dental Traumatology 5, no. 4 (August 1989): 182–87. http://dx.doi.org/10.1111/j.1600-9657.1989.tb00357.x.

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27

Nagaoka, Shigetaka, Youichi Miyazaki, Hong-Jih Liu, Yuko Iwamoto, Motoo Kitano, and Masataka Kawagoe. "Bacterial invasion into dentinal tubules of human vital and nonvital teeth." Journal of Endodontics 21, no. 2 (February 1995): 70–73. http://dx.doi.org/10.1016/s0099-2399(06)81098-8.

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28

Ulusoy, Nuran, Arun Nayyar, Charles F. Morris, and Carl W. Fairhurst. "Fracture durability of restored functional cusps on maxillary nonvital premolar teeth." Journal of Prosthetic Dentistry 66, no. 3 (September 1991): 330–35. http://dx.doi.org/10.1016/0022-3913(91)90259-y.

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MEYENBERG, KONRAD H., HEINZ LÜTHY, and PETER SCHÄRER. "Zirconia Posts: A New All-Ceramic Concept for Nonvital Abutment Teeth." Journal of Esthetic and Restorative Dentistry 7, no. 2 (March 1995): 73–80. http://dx.doi.org/10.1111/j.1708-8240.1995.tb00565.x.

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30

Inomata, Miyu, Akio Harada, Shin Kasahara, Taro Kusama, Akane Ozaki, Yusuke Katsuda, and Hiroshi Egusa. "Potential complications of CAD/CAM-produced resin composite crowns on molars: A retrospective cohort study over four years." PLOS ONE 17, no. 4 (April 7, 2022): e0266358. http://dx.doi.org/10.1371/journal.pone.0266358.

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Purpose Evaluation of the clinical performance of computer-aided design/computer-aided manufacturing-produced resin composite crowns (CAD/CAM composite crowns) on molars with a particular focus on placement location. Methods A retrospective cohort study was performed based on the clinical records of patients with CAD/CAM composite crowns on molars (June 2016 to March 2021). The hazard ratios (HRs) and 95% confidence intervals (95% CIs) were estimated based the Cox proportional hazard model to evaluate the effect of tooth location on complication type and occurrence. Covariates included crown location (maxilla/mandible, distalmost tooth/not distalmost tooth, and first molar/second or third molar) and endodontically treated (nonvital) or untreated (vital) tooth. Results Overall, 362 crowns were evaluated (mean follow-up: 378 days, median: 286 days), and 106 crowns (29.3%) showed complications, most frequently crown debonding. The cumulative success and survival rates were 70.9% and 93.7%, respectively, after 1 year and 49.5% and 86.5%, respectively, after 3 years. There was no significant difference in the HRs and log-rank tests in the Kaplan–Meier curves based on crown location parameters (P > 0.05). However, placement on vital teeth was associated with higher risks than on nonvital teeth (HR, 1.55; 95% CI, 1.03–2.23). In addition, the cement as a covariate yielded a high HR. Conclusions The location of CAD/CAM composite molar crowns is unlikely a risk factor for complications; therefore, these crowns can be clinically applied to all molars. However, the application of such molar crowns to vital teeth and the use of a cement other than adhesive resin cement present risks.
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Forghani, Maryam, Hamid Jafarzadeh, Jamileh Ghoddusi, Amir Maghsudlu, and Amirhossein Jafarian. "Histological Evaluation of the Effect of Platelet-rich Plasma on Pulp Regeneration in Nonvital Open Apex Teeth: An Animal Study." Journal of Contemporary Dental Practice 18, no. 11 (2017): 1045–50. http://dx.doi.org/10.5005/jp-journals-10024-2173.

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ABSTRACT Aim Platelet-rich plasma (PRP), which is a concentration of growth factors found in platelets, may be a suitable material for pulp regeneration. The aim of this animal study was a histological evaluation of PRP on pulp regeneration in nonvital teeth with immature apices. Materials and methods A total of 40 premolar dogs’ teeth were chosen for this study. After general anesthesia, the teeth were exposed, and subsequently, pulps were removed and the cavities were opened to the oral cavity. After 2 weeks, root canals were irrigated and disinfected with sodium hypochlorite with noninstrumentation technique, and triple antibiotic paste was placed inside the canals. Cavities were sealed with a temporary restoration. About 4 weeks later, canals were irrigated again and the teeth were randomly divided into three groups. Bleeding was evoked with overinstrumentation, then experimental materials for each group [PRP, mineral trioxide aggregate (MTA), and parafilm respectively] were placed over the bleeding, and orifices were sealed with MTA and glass ionomer. After 3 months, dogs were sacrificed and the teeth were separated from the jaws and sections prepared for histological evaluation. Results Regeneration was shown in 44.7% of the samples. About 47.3% of the samples in the MTA group and 42.1% of the samples in the PRP group showed regeneration; however, no regeneration was observed in the parafilm group. Chi-square test showed no significant difference between groups I and II. The soft regenerative tissue included pulp-like tissue and vessels. Mineralized regenerative tissue included cementumlike, periodontal ligament-like, and bone-like tissues. No normal pulp and nerve tissue were observed. Conclusion Both PRP and MTA may be ideal scaffolds to accelerate the regeneration process. Clinical significance Pulp repair in immature permanent teeth with weak roots has a better outcome than replacement of the pulp with gutta-percha or biomaterials. How to cite this article Ghoddusi J, Maghsudlu A, Jafarzadeh H, Jafarian A, Forghani M. Histological Evaluation of the Effect of Platelet-rich Plasma on Pulp Regeneration in Nonvital Open Apex Teeth: An Animal Study. J Contemp Dent Pract 2017;18(11):1045-1050.
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Palit, M. C., K. S. Hedge, S. S. Bhat, S. S. Sargod, S. Mantha, and S. Chattopadhyay. "Tissue Engineering in Endodontics: Root Canal Revascularization." Journal of Clinical Pediatric Dentistry 38, no. 4 (July 1, 2014): 291–97. http://dx.doi.org/10.17796/jcpd.38.4.j5285857278615r1.

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Root canal revascularization attempts to make necrotic tooth alive by the use of certain simple clinical protocols. Earlier apexification was the treatment of choice for treating and preserving immature permanent teeth that have lost pulp vitality. This procedure promoted the formation of apical barrier to seal the root canal of immature teeth and nonvital filling materials contained within root canal space. However with the success of root canal revascularization to regenerate the pulp dentin complex of necrotic immature tooth has made us to rethink if apexification is at the beginning of its end. The objective of this review is to discuss the new concepts of tissue engineering in endodontics and the clinical steps of root canal revascularization.
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Mishra, Preeti, Vineeta Nikhil, and Shikha Jaiswal. "Immediate esthetic rehabilitation of fracture vital and nonvital teeth: A noval approach." IP Indian Journal of Conservative and Endodontics 7, no. 1 (March 15, 2022): 36–38. http://dx.doi.org/10.18231/j.ijce.2022.007.

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Traumas that affect the hard tissues, cause functional and esthetic disturbances which are of great relevance especially when a patient is a public figure immediate treatment in such cases is mandatory for both esthetic and psychological reasons. In the pre-adhesive era, fractured teeth were restored either with pin retained restorations or metallic post. However, with development of adhesive dentistry more conservative approach can be adapted allowing the dentists to use the patient’s own fragment to restore the fractured tooth.This procedure termed as reattachment can lead to immediate esthetic restoration. This article present the two successful conservative management of reattachment procedure.
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Kosaka, Shigeru, Fumishiro Yanagida, Kohki Inabu, Yoshiki Morioka, Keizo Iwai, Mitsuharu Amari, and Tsuyoshi Osanai. "A Statistical Observation of Nonvital Teeth by Dental Films. Mostly about Post." Nihon Hotetsu Shika Gakkai Zasshi 36, no. 4 (1992): 842–50. http://dx.doi.org/10.2186/jjps.36.842.

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35

Orti, Valérie, Pierre-Yves Collart-Dutilleul, Sofía Piglionico, Orsolya Pall, Frédéric Cuisinier, and Ivan Panayotov. "Pulp Regeneration Concepts for Nonvital Teeth: From Tissue Engineering to Clinical Approaches." Tissue Engineering Part B: Reviews 24, no. 6 (December 2018): 419–42. http://dx.doi.org/10.1089/ten.teb.2018.0073.

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36

Kumar, Vinod, Mohammed Zameer, Vijaya Prasad, and T. Mahantesh. "Boon of MTA Apexification in Young Permanent Posterior Teeth." Case Reports in Dentistry 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/673127.

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Single visit apexification using mineral trioxide aggregate (MTA) is a new boon in effective management of nonvital tooth with an open apex which has steadily gained popularity with clinicians; also it shortens the treatment period and improves patient compliance. Importance of this approach lies in expedient cleaning and shaping of the root canal system, followed by its apical seal with MTA. There are several case reports available describing the use of MTA as an apexification agent in incisors and premolar, but presented cases are the unique case reports demonstrating successful apexification procedure using MTA in young permanent mandibular molars. After eight-month follow-up, teeth were without any abnormal clinical symptoms; rather there were radiographic resolution of the periapical lesion and induction of root end closure with new hard tissue formation over MTA.
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Sulakshana, Dr, Poornima P, Srinath S K, and Padmapriya S. "Revascularization of immature permanent teeth via blood clot or PRF Platelet rich fibrin: A review." RGUHS Journal of Dental Sciences 14, no. 3 (2022): 2–12. http://dx.doi.org/10.26715/rjds.14_3_2.

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Regenerative endodontic procedure in an immature nonvital tooth is a biological treatment approach. Case reports have shown clinical and radiographic success following regenerative procedures and successful continued root development as well as strengthening of the root structure. Even though the primary goal of this treatment is to regenerate functional pulp tissue, a different outcome has been shown in histological analysis. This review discusses the conventional and Platelet rich fibrin (PRF) revascularization and also histological analysis of regenerated tissue in the root canal in animal and human studies.
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Almeida, Dulce O., Sônia CL Chaves, Ronaldo A. Souza, and Felipe F. Soares. "Outcome of Single- vs Multiple-visit Endodontic Therapy of Nonvital Teeth: A Meta-analysis." Journal of Contemporary Dental Practice 18, no. 4 (2017): 330–36. http://dx.doi.org/10.5005/jp-journals-10024-2041.

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ABSTRACT Introduction Endodontic therapy is a specialized procedure more demanded by patients within public oral health care in the country. Then, single-visit endodontic therapy may offer advantages to the health care services, to the professionals, and to the patients by reducing access barriers. Materials and methods A meta-analysis was done and the variables evaluated were periapical repair, microbiological control, and postobturation pain in randomized clinical trials (RCTs) involving endodontic treatment of nonvital teeth at single- or multiple visits. Results About 17 RCTs were included. There were no differences found in periapical repair or microbiological control in single- and multiple-visit therapy. Single-visit endodontic therapy resulted in 21% less postobturation pain (relative risks = 0.79; 95%, confidence interval: 0.66-0.94). Conclusion There was less postobturation pain in the single-visit endodontic therapy group. In the public dental care, this analysis favors the adoption of this one therapy because it will be possible to increase the patient access and the supply of this therapy. Clinical significance It is possible to get a better cost-effectiveness for the patients and the health care service. This is very important because the reduction of the cost to the patient allows it to become a complete treatment. The health service, in turn, is able to be better used, with a greater supply of this service. How to cite this article Almeida DO, Chaves SCL, Souza RA, Soares FF. Outcome of Single- vs Multiple-visit Endodontic Therapy of Nonvital Teeth: A Meta-analysis. J Contemp Dent Pract 2017;18(4):330-336.
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Annamalai, Sankar, and Jayanthi Mungara. "Efficacy of Mineral Trioxide Aggregate as an Apical Plug in Non-Vital Young Permanent Teeth: Preliminary Results." Journal of Clinical Pediatric Dentistry 35, no. 2 (December 1, 2010): 149–55. http://dx.doi.org/10.17796/jcpd.35.2.9061h7g718834017.

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Purpose: The purpose of this study was to evaluate the efficacy of Mineral trioxide aggregate (MTA) clinically and radiographically as material used to induce root end closure in nonvital permanent teeth with immature apices (apexification) in children. Methods: The study included 30 non vital young permanent,single rooted teeth of 22 children between 8 and 13 years of age. Treatment followed a standard non-surgical root canal treatment protocol and the root canal was filled with a apical plug of 4-5 mm of MTA (white MTA – Angelus, Brazil), followed by gutta-percha obturation. The children were reviewed for 1 year at 3 month interval and the teeth were assessed clinically and radiographically. Results: MTA showed success rate of 100% both clinically and radiographically at the 12th months follow up and root end closure was seen in 86.6% of cases and root growth in 30% of cases. Conclusions: MTA showed clinical and radiographic success as an apexification material by inducing root end closure and root growth in non-vital young permanent teeth.
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Moosavi, Horieh, Jamileh Ghoddusi, Mohammad Javad Moghaddas, and Omid Rajabi. "Effects of Two Antioxidants on the Microleakage of Resin-Based Composite Restorations after Nonvital Bleaching." Journal of Contemporary Dental Practice 11, no. 6 (2010): 33–40. http://dx.doi.org/10.5005/jcdp-11-6-33.

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Abstract Aim The aim of this study was to compare the neutralizing effect of antioxidant agents on the microleakage of dental restorations in nonvital teeth after bleaching with carbamide peroxide. Also assessed was the correlation of the microleakage data between an electrochemical and a staining technique. Methods and Materials Following root canal therapy, 40 sound and similar human maxillary central incisors were randomly divided into four groups of 10 specimens each (n=10). The groups were subjected to one of four treatments: Group 1, bleaching with 10 percent carbamide peroxide for periods of eight hours per day for one week without an antioxidant agent; Group 2, bleaching with 10 percent carbamide peroxide plus 10 percent sodium ascorbate gel; Group 3, bleaching with 10 percent carbamide peroxide plus 10 percent sodium ascorbate gel combined with a surfactant; and Group 4, no bleaching treatment (control group). In all groups, the access cavities were restored using the Single Bond Plus Adhesive system and Z100 resin-based composite. After 1,000 thermal cycles, the teeth were dried and three layers of nail varnish were applied over the entire surface area to within 1.0 mm of the restoration. A PVC-covered copper wire, with 3.0 mm of exposed bare wire, was inserted apically 5.0 mm into the canal, which was obturated with gutta-percha and sealed with sticky wax and varnish at the apex. Leakage was continuously monitored for 40 days using a conductimetric method. The teeth were immersed in 0.5 percent basic fuchsine for 24 hours, followed by sectioning for microscopic examination at 16x magnification. The data were analyzed using ANOVA and the Newman-Keuls multiple comparison, Kruskal-Wallis, Mann-Whitney, and Spearman's rho tests (p<0.05). Results Based on the electrochemical results, cavities subjected to 10 percent sodium ascorbate gel combined with a surfactant displayed the least amount of microleakage while teeth that were bleached but not treated with an antioxidant exhibited significantly greater microleakage (p=0.007). These findings also were corroborated by the results of the staining experiments that showed a strong correlation between the electrochemical and staining findings (p=0.006) for the groups. Conclusion After nonvital bleaching and the application of the antioxidant 10 percent sodium ascorbate, the addition of the surfactant 0.2 percent Tween 80 to the conventional antioxidant formulation significantly reduced microleakage. Clinical Significance The addition of a surfactant to the antioxidant formulation significantly reduced microleakage when it was applied after bleaching. Citation Moosavi H, Moghaddas MJ, Ghoddusi J, Rajabi O. Effect of Two Antioxidants on the Microleakage of Resin-Based Composite Restorations after Nonvital Bleaching. J Contemp Dent Pract [Internet]. 2010 December; 11(6):033- 040. Available from: http://www.thejcdp.com/ journal/view/volume11-issue6-moosavi
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41

Issar, Rashmi, Shashi Ranjan, Priyankar Singh, Deirimika Lakiang, and Ravindra Kole. "Correlation of postoperative pain in vital versus nonvital teeth: A clinical prospective study." Journal of Indira Gandhi Institute Of Medical Sciences 7, no. 1 (2021): 52. http://dx.doi.org/10.4103/jigims.jigims_1_20.

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42

Muthiah, Gomagal, Ponnudurai Arangannal, J. Jeevarathan, and P. Sankar. "Lesion sterilization and tissue repair in nonvital primary teeth: An In vivo study." Contemporary Clinical Dentistry 10, no. 1 (2019): 31. http://dx.doi.org/10.4103/ccd.ccd_124_18.

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43

Agarwal, Manish, Anu Narang, Shilpi Awadhiya, and Mahendra Jain. "Nonvital Bleaching: A Case Series on whitening Procedure for Discolored Endodontically Treated Teeth." International Journal of Prosthodontics and Restorative Dentistry 8, no. 1 (2018): 28–31. http://dx.doi.org/10.5005/jp-journals-10019-1198.

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44

Homsy, Foudda, Rita Eid, Wiam El Ghoul, and Jose Johann Chidiac. "Considerations for Altering Preparation Designs of Porcelain Inlay/Onlay Restorations for Nonvital Teeth." Journal of Prosthodontics 24, no. 6 (March 5, 2015): 457–62. http://dx.doi.org/10.1111/jopr.12279.

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45

Ikeda, Hideharu, and Hideaki Suda. "Subjective sensation and objective neural discharges recorded from clinically nonvital and intact teeth." Journal of Endodontics 24, no. 8 (August 1998): 552–56. http://dx.doi.org/10.1016/s0099-2399(98)80076-9.

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46

Miyasaki, E., C. E. S. Bueno, K. Okino Neto, G. Meneghine, and R. Hizatugu. "PR 2 Post-operative pain after root canal treatment in symptomatic nonvital teeth." Journal of Endodontics 25, no. 4 (April 1999): 298. http://dx.doi.org/10.1016/s0099-2399(99)80226-x.

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47

Villagrán Colón, Víctor Ernesto, Mirna Oldemia Calderón Márquez, Ricardo Alfredo Carrillo-Cotto, Flavio Fernando Demarco, and Luiz Alexandre Chisini. "Dentist’s preferences on vital and nonvital tooth bleaching." Brazilian Journal of Oral Sciences 20 (February 8, 2021): e211711. http://dx.doi.org/10.20396/bjos.v20i00.8661711.

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Aim: The present study aimed to investigate if the Guatemalan dentist’s options on tooth bleaching could be influenced by their time in clinical practice, the level of specialization or their working place. Methods: A representative sample of dentists working in clinical practice in Guatemala was selected. Data were collected using a self-administered questionnaire with information related to gender, professional characteristics (time since graduation in years and working place) and preferences regarding vital (at-home or in-office; type and concentration of bleaching agent) and the nonvital tooth bleaching (bleaching agent used). The analysis was performed and the association between preference for bleaching technique and independent variables were investigated using Fisher’s exact test. Results: 200 dentists were interviewed. More than half of dentists were male (57.0%) with time since graduation between 11 and 20 years (n= 64; 32.3%). Dentists mostly (60.5%) preferred in-office technique for vital bleaching, with 10-20% Carbamide peroxide (CP) as the preferred agent (50%). For nonvital teeth, the preferred agent (46.8%) was 37% Hydrogen Peroxide (HP). About the associations, younger dentists (< 20 years of graduation) selected mostly in-office technique, while those with more than 20 years indicated more the at-home technique. Also, the dentists working in private practice chose more frequently in-office technique. Thus, the in-office technique was more popular among Guatemalan dentists, with 10-20% CP and 37% HP selected as favorite bleaching agents for vital and nonvital techniques, respectively. Conclusion: The time of clinical practice and working place influenced some choices.
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Shin, Su-Jung, Woocheol Lee, Jae-Il Lee, Seung-Ho Baek, Kee-Yeon Kum, Won-Jun Shon, and Kwang-Shik Bae. "Matrix metalloproteinase-8 and substance P levels in root canal exudates of nonvital teeth." Journal of Korean Academy of Conservative Dentistry 36, no. 3 (2011): 196. http://dx.doi.org/10.5395/jkacd.2011.36.3.196.

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Rani, Anuradha, and Ashok Chopra. "Isolation and Identification of Root Canal Bacteria from Symptomatic Nonvital Teeth With Periapical Pathosis." Endodontology 18, no. 1 (2006): 12. http://dx.doi.org/10.4103/0970-7212.351835.

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Silujjai, Jidapa, and Pairoj Linsuwanont. "Treatment Outcomes of Apexification or Revascularization in Nonvital Immature Permanent Teeth: A Retrospective Study." Journal of Endodontics 43, no. 2 (February 2017): 238–45. http://dx.doi.org/10.1016/j.joen.2016.10.030.

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