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Добірка наукової літератури з теми "Non malignant uterine diseases"

Автор: Grafiati

Опубліковано: 3 листопада 2022

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Статті в журналах з теми "Non malignant uterine diseases"

Basnet, Sunila, Shiva Raj KC, and Geetika KC. "Uterine Cervix-Benign Histomorphological Spectrum." Nepalese Medical Journal 1, no. 1 (June 22, 2018): 1–4. http://dx.doi.org/10.3126/nmj.v1i1.20389.

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Introduction: Non neoplastic lesions of cervix form a wide variety of lesions in the cervical biopsy specimen or hysterectomy specimens. Chronic cervicitis is the commonest finding; but can be associated with other underlying pathologies. In our study we aim to study and categorize the morphology of non neoplastic lesions of cervix in cervical biopsy specimen or hysterectomy specimens into inflammatory, reparative or reactive lesions, glandular hyperplasia, metaplasia and ectopies and benign neoplasm.Materials and Methods: This is a retrospective study that consisted of 520 slides retrieved from the records of department of histopathology KIST medical college. Whenever required block were retrieved and recut sections were made. All the benign lesions were included in the study.Results: The commonest lesions diagnosed were inflammatory, reparative or reactive changes 513 (98.6%) cases, followed by metaplastic changes 311 (59.8%) and glandular hyperplasia in 44 cases (8.4%). Benign neoplasms were seen in 33(6.3%) cases.Conclusions: Cervix is a target organ for varieties of neoplastic and non neoplastic diseases. There are many benign mimics of malignant cervical lesions. It may be difficult to interpret adequately in a small biopsy specimen however it is necessary to distinguish between these benign lesions and their mimics to prevent unnecessary inappropriate treatment to the patient.Nepalese Medical Journal. vol.1, No. 1, 2018, Page : 1-4

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Palcic, B., D. Garner, and X. R. Sun. "Detection of Early Cancers by Quantitative Cytology." Microscopy and Microanalysis 6, S2 (August 2000): 1010–11. http://dx.doi.org/10.1017/s1431927600037545.

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It has long been recognized that detecting cancers in their early, non-invasive stage is the best strategy to control malignant diseases. This has been best demonstrated by the example of cancer of the uterine cervix. Before screening for early signs of this malignancy, the prevalence of invasive cancer of the uterine cervix in the developed world was as high as 30 women per 100,000 and the mortality was 12-15 per 100,000 women per year, (all figures represent age standardized data). Since the introduction of cervical screening programs by Pap smears, the incidence of invasive cervical cancer and mortality due to this cancer has fallen dramatically. In British Columbia, for example, where population screening was introduced 50 years ago, the incidence and mortality have decreased several-fold and are at present below 6 and 3 per 100,000, respectively (1,2). It is believed that these figures could be even lower by encouraging more women into the program and by improving both sensitivity and specificity of the cytology.

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Micheletti, Adilha Rua, Ana Carolina Sandoval Macedo, Gisele Barbosa e. Silva, Ana Cristina Araújo Lemos da Silva, Mário Leon Silva-Vergara, Eddie Fernando Cândido Murta, and Sheila Jorge Adad. "Benign and malignant neoplasias in 261 necropsies for HIV-positive patients in the period of 1989 to 2008." Revista do Instituto de Medicina Tropical de São Paulo 53, no. 6 (December 2011): 309–14. http://dx.doi.org/10.1590/s0036-46652011000600002.

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Considering that there are some studies with autopsies from AIDS describing only malignant neoplasias and that changes can occur after the introduction of Highly Active Antiretroviral Therapy (HAART), our objectives were to analyze the frequency of benign and malignant neoplasms in AIDS patients in the periods of both pre- and post-HAART. This is a retrospective study with 261 autopsies of HIV-positive patients between 1989 and 2008 in Uberaba, Brazil. Sixty-six neoplasms were found (39 benign, 21 malignant and six premalignant) in 58 patients. The most frequent malignant neoplasms were lymphoid, in 2.7% (four Non-Hodgkin lymphoma, one Hodgkin, one multiple myeloma and one plasmablastic plasmacytoma), and Kaposi's Sarcoma, in 2.3% (six cases). The most frequent benign neoplasms were hepatic hemangiomas in 11 (4.2%) of 261 cases and uterine leiomyoma in 11 (15.7%) of 70 woman. In the pre-HAART period eight (9.8%) benign neoplasias and four (4.9%) malignant occurred in 82 patients; in the post-HAART period, 29 (16.2%) benign and 17 (9.5%) malignant were present; however, the differences were not significant. We conclude that the introduction of HAART in our region doesn't look to have modified the frequency of neoplasms occurring in patients with HIV.

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Beneventi, F., E. Locatelli, G. Giorgiani, M. Zecca, F. Locatelli, C. Cavagnoli, M. Simonetta, S. Bariselli, B. Negri, and A. Spinillo. "Gonadal and uterine function in female survivors treated by chemotherapy, radiotherapy, and/or bone marrow transplantation for childhood malignant and non-malignant diseases." BJOG: An International Journal of Obstetrics & Gynaecology 121, no. 7 (March 24, 2014): 856–65. http://dx.doi.org/10.1111/1471-0528.12715.

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Petkova, Kristina, and Venci Chalkov. "THE ROLE OF TUMOR MARKERS CA 125, CA 72-4 AND CA 19-9 IN DETECTION AND MONITORING OF THE COURSE OF DISEASE OF OVARIAN CARCINOMA AND CARCINOMA OF THE UTERINE BODY." Teacher of the future 31, no. 4 (June 5, 2019): 931–36. http://dx.doi.org/10.35120/kij3104931p.

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Undoubtedly, nowadays the number of patients suffering from benign or malignant tumors is increasing. Particularly affected is the female population with ovarian cancer, carcinomas of the uterine body and non-inflammatory diseases of the ovary, the oviduct and the broad ligament and other benign conditions. Carcinoma is one of the most common causes of mortality in our country, as well as in the Balkans. In our country malignant tumors occupy third place in terms of total patients treated, after diseases of the respiratory and circulatory system. Due to the rapid increase in the number of patients with the following diagnoses: ovarian carcinoma, uterine carcinoma, non-inflammatory ovarian disease, oviduct, broad ligament and other benign conditions, their timely diagnosis is of great importance for the possibility of their treatment and reducing the percentage of mortality. When setting the diagnosis, tumor markers have an important role, whose elevated blood concentrations indicate changes of benign or malignant origin. Tumor markers are substances (proteins, enzymes, hormones, etc.) secreted in the body as a consequence of its response in the presence of a benign or malignant change. Their measurement and identification is useful for establishing the diagnosis, as well as for monitoring the course of the disease and the success of the therapy. Tumor markers are usually determined in blood, urine or tissue samples using specific, immunochemical laboratory methods. In the medical practice, about 30 different tumor markers are used, but in the diseases that are subject of our research commonly are used the following: CA 125, CA 72-4 and CA 19-9. Besides these tumor markers, as a new tumor marker, in this research project is mentioned HE4 (human epididymis protein 4). HE4 in combination with CA 125 assists in determining the type of tumor mass (benign or malignant), through algorithm for estimating the risk of ovarian cancer (Risk of Ovarian Malignancy Algorithm - ROMA). The goals of this paper are: regular control of healthy women and women who have an increased risk of developing carcinoma (family history), diagnosing carcinomas, estimating the prognosis of the disease (prognostic factor), and monitoring the course of the disease and the success of applied therapy (postoperatively) by determining the concentration of tumor markers CA 125, CA 72-4 and CA 19-9 in blood serum, in combination with other examinations (echo, swab, PAP test, Power color doppler, etc.). For the realization of these goals as a method of work, the concentrations of tumor markers CA 125 and CA 19-9 in blood serum were determined using the apparatus - Immulite 2000 which works on the principle of chemiluminescent method, as well as the determination of the concentration of tumor marker CA 72-4 in blood serum using an ELISA (enzyme linked immunosorbent assay) method. On the basis of the results obtained, we came to the conclusion that the concentrations of tumor markers CA 125, CA 72-4 and CA 19-9 in the blood serum increase in the occurrence of ovarian carcinoma, uterine carcinoma, non-inflammatory ovarian disease, the oviduct and broad ligament and other benign conditions, and that they are reduced postoperatively and with applied therapy, with the exception of patients who have metastases also on other parts of the body, where their concentrations are still rising or remain unchanged. Due to the outcome of these types of diseases, regular controls are recommended for the female population.

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Sagidullina, G., А. Mukazhanov, А. Kukhareva, and М. Meirmanova. "Application of focused ultrasound in oncology: fundamentals and perspectives (literature review)." Oncologia i radiologia Kazakhstana 58, no. 4 (December 31, 2020): 60–65. http://dx.doi.org/10.52532/2521-6414-2020-4-58-60-65.

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Relevance: The introduction into clinical practice of new non-invasive, safe and effective methods of treatment of benign and malignant diseases is an urgent task. The purpose was to study literature sources on the experience of using MRI-guided focused ultrasound (MRgFUS) method of thermal ablation for its subsequent implementation and use at the East Kazakhstan Region Multidisciplinary Center of Oncology and Surgery of Ust-Kamenogorsk. Results: The proposed method is based on real-time MRI-guided thermal ablation by focused ultrasound. Numerous studies have shown its clinical and economic efficiency, safety, and convenience for patients with bone metastases, early-stage prostate cancer, and uterine myoma. Conclusions: MRgFUS ablation is a modern non-invasive technique that expands the ways to treat benign and malignant tumors. In certain cases, it can be a good alternative to invasive treatments. MRgFUS ablation can be used in combination with other treatments.

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Al-Muzian, Lubna, Mohammed Almuzian, Hisham Mohammed, Aman Ulhaq, and Alexander J. Keightley. "Are developmentally missing teeth a predictive risk marker of malignant diseases in non-syndromic individuals? A systematic review." Journal of Orthodontics 48, no. 3 (January 18, 2021): 221–30. http://dx.doi.org/10.1177/1465312520984166.

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Background: Different genes and loci that are associated with non-syndromic developmental tooth agenesis (TA) have the same causation pathway in the development of tumours including breast cancer (BC), epithelial ovarian cancer (EOC), colorectal cancer (CRC) and lung cancer (LC). Objectives: To assess the link between TA and the development of cancer. Search sources: This registered review included a comprehensive search of electronic databases (Cochrane Central Register of Controlled Trials [CENTRAL], LILACS, Scopus, Web of Science and Medline via Ovid) until 1 April 2020, supplemented by manual, grey literature and reference lists search. There was no restriction in term of date of publication, gender, race or type of hypodontia. Data selection: The primary outcome was the relationship between TA and cancer. The secondary outcome was to identify the genetic correlation between TA and cancer. Data extraction: Study selection, data extraction and risk of bias assessment were performed independently and induplicate by two reviewers, with disputes resolved by a third reviewer. Results: Eight studies with a moderate-high risk of bias were included in the final review, with a total of 5821 participants. Due to the heterogeneity among the included studies, the data were presented narratively. Limited studies reported a high prevalence of EOC (19.2%–20%) and CRC (82%–100%) in individuals with TA (depending on the study) compared to those without TA (3% for EOC and 0% for CRC). While others reported a weak correlation between EOC and CRC and TA ( P > 0.05). Weak evidence suggested a strong correlation between breast, cervical uterine and prostate cancers and TA ( P < 0.05). Conclusions: Though low-quality evidence suggests a link between TA and cancer, it was not possible to verify that TA can hold a predictive value as a marker for cancers. Further research is needed to confirm the association. Registration: PROSPERO (CRD42020139751).

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Samoilіuk, G. V. "Prevalence of tumor pathology of dogs in the metropolis." Theoretical and Applied Veterinary Medicine 9, no. 2 (2021): 98–104. http://dx.doi.org/10.32819/2021.92016.

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A statistical analysis of the prevalence of tumor pathology of dogs in the city of Dnipro. 418 cases of registered oncological diseases of dogs were analyzed. It was found that malignant neoplasms are 1.5 times more common than benign. The most common tumors in dogs are tumors of the breast (35,9%), skin (22,0%), genitals (15,3%) and lymphoma(8,4%). Malignant neoplasms of the breast are registered 3.6 times more often than benign and surpass them in morphological varieties. Fibroadenomas and infiltrating and non-infiltrating carcinomas were mainly registered. Approximately the same number of cases of infiltrating and non-infiltrating cancers were noted. Benign skin tumors are more common than malignant. Mastocytosis, melanoma, and squamous and basal cell carcinomas of the skin and sebaceomas were the most commonly reported. In terms of morphological varieties, benign skin neoplasms are superior to malignant ones. Lipomas and papillomas are very common. Genital neoplasms of females and males are also common. Almost half of male genital tumors were malignant seminomas. Among benign neoplasms, serteliomas and leydigomas were more common. In females, the most common are uterine leiomyoma, vaginal fibroma and ovarian carcinoma. Lymphomas (8.4%) are also widespread in dogs in the metropolis. The average age of registration of these neoplasms was 7.5 years. Benign tumors in the oral cavity of dogs were twice as common as malignant, of which fibrosarcomas, squamous keratinized and non-keratinized carcinomas, and salivary gland adenocarcinomas were reported. In females, oral neoplasia occurred 3.2 times more often than in males. Only malignant venereal sarcomas and carcinomas were found in the nasal cavity of dogs. Sexual and pedigree predisposition was not observed here. Among neoplasms of muscles and bones there was only a malignant oncological pathology. Rhabdomyosarcomas, fibrosarcomas, myxoid liposarcomas and other soft tissue sarcomas were diagnosed in different parts of the dog’s body. Bone neoplasms are represented by osteosarcomas. Dogs of large breeds were most often affected and in most cases the hind limbs were affected. The predominant histological subtype was osteoblastic osteosarcoma.

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Petrovic-Rodic, Dusica, Tatjana Kastratovic, Danijela Jovanovic, Vladan Markovic, Jasmina Stojanovic, and Dalibor Jovanovic. "Lymphoma of the uterine cervix- a rare clinical presentation: A case report." Vojnosanitetski pregled, no. 00 (2021): 80. http://dx.doi.org/10.2298/vsp210707080p.

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Background/Aim. Lymphomas are malignant diseases of lymphocytes. There are two basic types of lymphoma: Hodgkin's lymphoma (HL) whose main characteristic is the presence of Reed-Sternberg cells and non-Hodgkin's lymphoma (NHL), which presents a heterogeneous group of diseases, and depending on the growth rate and the course of the disease, they can be indolent (slow-growing) and aggressive (fast-growing). Follicular lymphoma (FL) is the most common indolent form of NHL, while diffuse large B-cell lymphoma (DLBCL) is the most common aggressive form. Case report. This paper presents a case of NHL, DLBCL, localized in the cervix, histo-pathologically diagnosed in a 35-year-old woman who, after a cervical biopsy, was patho-histologically diagnosed with mild dysplasia (CIN1 / L-SIL) of the cervical epithelium and, after that, an infection with Human Papilloma Virus (HPV), subtypes 16 and 31 was proven. The diagnosis of DLBCL was patho-histologically confirmed on a conical section of the vaginal portion of the uterus, after which the disease was treated with eight cycles of chemotherapy (HT) according to the RCHOP protocol. Conclusion. The coexistence of CIN1 / L-SIL and NHL is random and may overlook concomitant cervical lymphoma, which is usually localized subepithelially, if the biopsy is not adequately performed and if HPV serotyping is not performed.

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Bergen, T. A., I. A. Soynov, V. A. Fokin, and G. E. Trufanov. "Magnetic resonance imaging prospects of prognostic value in women pelvic pathology." Сибирский научный медицинский журнал 41, no. 2 (April 28, 2021): 49–55. http://dx.doi.org/10.18699/ssmj20210207.

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Aim of the study was to estimate the prognostic value of perfusion and diffusion magnetic resonance imaging (MRI) methods in systemic evaluation of perifocal changes of malignant masses in women’s pelvis. Material and methods. A retrospective analysis of MRI of the pelvic organs in women was performed on MRI scanners with a magnetic field of 1.5 T (Philips Achieva, Netherlands). The retrospective study included 1,5 T MRI of 530 women with pelvis pathology. It consists of 50 % (265 cases) of malignant pelvic mass and 50 % (265 cases) of non tumor pathologies. The most common malignant pathologies were regarded: rectum cancer (n=61), ovarian cancer (n=62), uterine cancer (n=65), cervical cancer (n=77). Group with non-tumor pathology was taken as comparison group and included inflammation (abscess), adhesions and other non-tumor pelvic pathologies (pseudocyst of peritoneum, hemorrhagic cyst, endometriosis). In all cases a body coil was used on pelvic region. MRI protocols included T2-, T1 – weighted imaging, diffusion weighted imaging, postcontrast T1 - weighted imaging. apparent diffusion coefficient value and perfusion value were estimated. Results and discussion. In intergroup comparison with systemic evaluation of MRI with ANOVA we revealed that the diffusion restriction and the apparent diffusion coefficient bear potential value for disease prognosis. Conclusions. MRI can be of value not only for evaluation of local spread, as well as providing wide opportunities for differential diagnosis and use of MRI as biomarker in some diseases. Such indications as restricted diffusion, apparent diffusion coefficient value and type of dynamic curve from perifocal lesion can benefit disease prognosis.

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Більше джерел

Дисертації з теми "Non malignant uterine diseases"

Madika, Anne-Laure. "Association entre les facteurs hormonaux et reproductifs et le risque d’hypertension artérielle dans la cohorte prospective E3N." Electronic Thesis or Diss., Université de Lille (2022-....), 2022. http://www.theses.fr/2022ULILS011.

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L’hypertension artérielle (HTA) est le premier facteur de risque cardiovasculaire et leplus souvent non diagnostiquée. Certains facteurs hormonaux et reproductifs sontsusceptibles d’être associés à l’HTA avec des données encore discordantes dans lalittérature.L’objectif de cette thèse était d’étudier l’association entre différents facteurshormonaux (traitement hormonal de la ménopause), reproductifs (âge à la ménopause,âge à la ménarche) et certains antécédents gynécologiques (hystérectomie,endométriose, fibrome utérin) et le risque d’HTA incidente dans la large cohorteféminine E3N (Étude épidémiologique auprès de femmes de l’Éducation nationale).Il s’agit d’une cohorte prospective portant sur 98 995 femmes âgées de 40 à 65 ans àl’inclusion en 1990. L’étude E3N inclut des données détaillées sur l’hygiène de vie,l’histoire clinique, les facteurs hormonaux et reproductifs, ainsi que sur la survenued’une HTA. Les Hazard ratio du risque d’HTA associé aux variables d’exposition étaientestimés à l’aide d’un modèle de Cox.Le risque d’HTA était majoré chez les femmes avec un antécédent d’hystérectomie avecou sans ovariectomie, d’endométriose ou de fibrome utérin, en cas de ménopauseprécoce (avant 40 ans) ou de ménarche précoce (avant 12 ans). Les femmes utilisatricesde traitement hormonal de la ménopause avaient un risque modérément augmenté dedévelopper une HTA, particulièrement en cas d’utilisation des oestrogènes combinéspar voie orale et de certains types de progestatifs.Ainsi nos résultats suggèrent de proposer des modifications de l’hygiène de vie pourprévenir l’HTA et de la dépister chez les femmes présentant ces antécédents en vued’une amélioration du pronostic cardiovasculaire
Hypertension is the leading cardiovascular risk factor worldwide and most often a silentand undiagnosed one. Hormonal and reproductive factors are likely to be associatedwith hypertension, but some discrepancies remain in the literature.The main objective of this thesis was to study the association between differenthormonal factors (menopause hormone therapy, reproductive factors (age atmenopause, age at menarche) and nonmalignant gynaecological diseases and theirtreatment (hysterectomy, endometriosis, uterine fibroids) and the risk of incidenthypertension in the large E3N female cohort (Étude épidémiologique auprès defemmes de l’Éducation nationale).This is a prospective cohort, which included 98,995 women aged 40–65 years atinclusion in 1990. The E3N study collected detailed data on lifestyle, clinical history,hormonal and reproductive factors, and the occurrence of hypertension. The HazardRatios of the risk of hypertension associated with the exposure variables wereestimated using a Cox model.The risk of hypertension was increased in women with a history of hysterectomy withor without oophorectomy, endometriosis, or uterine fibroids, in case of earlymenopause (before 40 years) or early menarche (before 12 years). Women usingmenopause hormone therapy had a moderately increased risk of developinghypertension, especially when using combined oral oestrogen and certain types ofprogestogens.Our results suggest implementing lifestyle modifications to prevent hypertension andencourage its screening in women presenting with these factors to improvecardiovascular outcomes

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Swan, Flavia Eirwen Serena. "A preliminary investigation of the hand-held fan and the Calming Hand for the management of chronic refractory breathlessness in patients with advanced malignant and non-malignant diseases." Thesis, University of Hull, 2016. http://hydra.hull.ac.uk/resources/hull:15139.

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Background Chronic breathlessness is a devastating symptom of advanced cardio-respiratory diseases, with extensive consequences for patients and their family carers. Despite optimal management of the underlying disease, problems may persist. Non-pharmacological interventions such as the hand-held fan and the Calming Hand may offer benefits, however there is little supportive evidence. Aim To gain preliminary data about the effectiveness of the hand-held fan and the Calming Hand for the management of exertion-induced breathlessness in people with chronic breathlessness. Methods Mixed method study with integrated findings; Systematic literature review and meta-analyses of airflow; feasibility 2x2 factorial, randomised controlled trial of the handheld fan and/or Calming Hand for the relief of exertion-induced acute-on-chronic breathlessness. Qualitative interviews of patients and carers. Findings Review findings indicate that airflow delivered from the hand-held fan at rest provides discernible breathlessness relief. The “2x2 factorial, pragmatic phase II trial of the Calming Hand and hand-held fan was feasible in terms of recruitment, data completion and trial acceptability. These preliminary results supported use of the fan for exertion-induced breathlessness including for time and rate of recovery after exertion-induced breathlessness. Qualitative data indicated that faster recovery improved patient self-efficacy and confidence. Patients identified the fan as a helpful “medical” device that played a useful role as part of a complex intervention for breathlessness. Conversely, there was little indication from quantitative or qualitative data to signal worthwhile benefit from the Calming Hand. The best candidate primary outcome measure was judged to be recovery rate or recovery time from exertion-induced breathlessness. Conclusion A future definitive trial is feasible to assess the benefits of the hand-held fan with exertion induced breathlessness. Breathlessness recovery rate and the recovery time are novel outcomes that may potentially reflect important patient improvements with exercise. The hand-held fan represents a tool that helps to promote patient self-mastery of breathlessness. These data do not support the use of the Calming Hand.

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Книги з теми "Non malignant uterine diseases"

Benign to malignant progression in cervical squamous epithelium. New York: Igaku-Shoin, 1994.

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Scott, Ann. Trigger point injections for chronic non-malignant musculoskeletal pain: Ann Scott, Bing Guo. Edmonton, Alta: Alberta Heritage Foundation for Medical Research, 2005.

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Hain, Richard D. W., and Satbir Singh Jassal. Specific non-malignant diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198745457.003.0017.

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The number of life-limiting conditions in paediatrics is vast, and paediatric palliative medicine is generally based equally on both malignant and non-malignant conditions. There are several medical conditions that are common enough for it to be helpful to know about them in more detail. As all the conditions, by definition, have no cure, it is best to tackle each symptom with which the child presents individually, never forgetting that medical intervention is not the only modality open to us. Common conditions, such as Duchenne muscular dystrophy, mucopolysaccharidosis type 1, mucopolysaccharidosis type 3, Batten’s disease, spinal muscular atrophy, and trisomy 18, are covered in this chapter. Details of clinical features and prognosis are described for each.

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Oliver, Nora, and Elizabeth Chiao. Malignant Diseases in HIV. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0033.

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Malignancies were one of the earliest recognized manifestations that led to the eventual description of the AIDS epidemic. Kaposi’s sarcoma was one of the first entities described in association with AIDS. Subsequently, intermediate-grade and high-grade non-Hodgkin’s lymphoma, invasive cervical cancer, and primary central nervous system lymphoma were defined by the Centers for Disease Control and Prevention as “AIDS-defining conditions.” Since the advent of combination antiretroviral therapy, several other cancers that are not AIDS-defining have been found to have an increased incidence in patients with HIV. These include, but are not limited to, Hodgkin’s disease and anal, liver, lung, oropharyngeal, colorectal, and renal cancers. They are generally referred to as “non-AIDS-defining cancers.” The increasing longevity of persons living with HIV as well as concurrent modifiable risk factors such as tobacco use may also influence the epidemiology of these malignancies.

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Pall iative care for adults with non-malignant diseases: Developing a national policy. London: National Council for Hospice and Specialist Palliative Care Services, 2003.

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Report to the Workers' Compensation Board on respiratory complications among workers receiving compensation for non-malignant respiratory disease. Toronto: Industrial Disease Standards Panel, 1993.

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United States. Agency for Health Care Policy and Research, ed. Treatment of common non-cancerous uterine conditions: Issues for research : Garden City, Long Island, New York, May 1994. Rockville, MD (Suite 501, 2101 East Jefferson St., Rockville 20852): U.S. Dept. of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, 1995.

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United States. Agency for Health Care Policy and Research., ed. Treatment of common non-cancerous uterine conditions: Issues for research : Garden City, Long Island, New York, May 1994. Rockville, MD (Suite 501, 2101 East Jefferson St., Rockville 20852): U.S. Dept. of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, 1995.

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Bunker, Professor Christopher, and Dr Arani Chandrakumar. Dermatological diseases and emergencies. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199565979.003.00017.

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Chapter 17 covers dermatological diseases and emergencies including a general introduction to the subject, followed by information on erythroderma, drug eruptions, angio-oedema, Kawasaki disease, staphylococcal toxic shock syndrome, Streptococcal toxic shock syndrome (streptococcal TSS), staphylococcal scalded skin syndrome, necrotizing fasciitis, psoriasis, eczema and dermatitis, cutaneous vasculitis, immunobullous disorders, pyoderma gangrenosum, scarring alopecia, herpes simplex viruses 1 and 2, varicella zoster virus infection, bacterial infections affecting the skin, fungal infections affecting the skin, ectoparasitic disease, HIV infection and the skin, malignant melanoma, non-melanoma skin cancer, and cutaneous T cell lymphoma.

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Carton, James. Gynaecological pathology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198759584.003.0012.

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This chapter covers gynaecological pathology and includes vulval skin diseases, benign vulval tumours, vulval carcinoma, vaginal infections, vaginal tumours, cervical carcinoma, cervical screening, endometriosis, endometrial carcinoma, uterine leiomyomas (fibroids), uterine leiomyosarcoma, functional ovarian cysts, benign non-epithelial ovarian tumours, benign epithelial ovarian tumours, borderline epithelial ovarian tumours, ovarian carcinomas, pelvic inflammatory disease, ectopic pregnancy, polycystic ovarian syndrome, hydatidiform mole, and pre-eclampsia.

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Частини книг з теми "Non malignant uterine diseases"

Mirzaei, Hamed, Neda Rahimian, Hamid Reza Mirzaei, Javid Sadri Nahand, and Michael R. Hamblin. "MicroRNAs in Non-Malignant Diseases." In Exosomes and MicroRNAs in Biomedical Science, 41–68. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-79177-2_3.

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Falkeis-Veits, Christina, and Michael Vieth. "Non-malignant Helicobacter pylori-Associated Diseases." In Advances in Experimental Medicine and Biology, 121–34. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/5584_2019_362.

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Willem Hendrik Leer, Jan, Paul van Houtte, and Jaap Davelaar. "Irradiation of Non-malignant Diseases: An International Survey." In Radiotherapy for Non-Malignant Disorders, 121–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-68943-0_6.

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Sänger, Nicole, Michael von Wolff, and Frank Nawroth. "Treatment of Uterine Bleeding During Chemotherapy." In Fertility Preservation in Oncological and Non-Oncological Diseases, 253–60. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-47568-0_28.

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Micke, Oliver, Axel Koehler, and Michael Heinrich Seegenschmiedt. "Where There is No Evidence: Registry for Rare Benign Diseases." In Radiotherapy for Non-Malignant Disorders, 701–23. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-68943-0_40.

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Seegenschmiedt, Michael Heinrich, and Oliver Micke. "Patterns-of-Care Study for Non-malignant Diseases in Germany." In Radiotherapy for Non-Malignant Disorders, 133–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-68943-0_7.

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Jarisch, Andrea, and Ariane Germeyer. "Non-Malignant Diseases Requiring Stem Cell Transplantation." In Fertility Preservation in Oncological and Non-Oncological Diseases, 115–22. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-47568-0_14.

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Trott, Klaus-Rüdiger, and Friedrich-Hugo Kamprad. "Side Effects and Long-Term Risks from Radiotherapy of Non-malignant Diseases." In Radiotherapy for Non-Malignant Disorders, 29–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-68943-0_2.

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Jiménez-Ayala, Matías, and Beatriz Jiménez-Ayala. "Cytopathology of the Non-Epithelial Malignant Tumors of the Uterine Corpus." In Monographs in Clinical Cytology, 69–81. Basel: KARGER, 2008. http://dx.doi.org/10.1159/000117520.

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Kröger, Nicolaus. "Applications of Haploidentical SCT in Patients with Non-malignant Diseases." In Stem Cell Biology and Regenerative Medicine, 141–47. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-65319-8_10.

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Тези доповідей конференцій з теми "Non malignant uterine diseases"

"Immature teratoma." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685328.

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Introduction: Immature teratoma represents 3% of all teratomas, 1 % of all ovarian cancers and 20% of malignant ovarian germ cell tumors. It is found either in pure form or as a component of a mixed germ cell tumor. It occurs essentially during the first two decades of life. According to WHO, immature teratoma is defined as a teratoma containing a variable amount of immature embryonal type neuroectodermal tissue Case: We present here a report of 23 years old unmarried female who presented with complaint of abdominal pain since 1 month and her CT scan done outside, showed fibroid uterus. She had history of typhoid fever 1 month back for which USG was done which suggested large uterine fibroid. On examination she was hemodynamically stable. On abdominal examination a non-tender supra-pubic mass of 24 weeks size with firm consistency, irregular margin was felt. On investigation CA 125 was 64.90 IU/L, LD- 223, beta HCG- 1.14. On MRI a large abdomino-pelvic lesion, likely left adnexal lesion with multiple cystic areas, with hemorrhage, with ascites and enlarged retroperitoneal lymph nodes with omental infiltration suggestive of a possibility of malignant germ cell tumor. In view of large ovarian tumor, possibly malignant decision for staging laparotomy was taken. Intra-operatively a large irregular vascular solid mass of 20 x 20 cms with bosselated appearance with few cystic lesions over it was seen, arising from left ovary and was sent for frozen section which reported malignant mature teratoma with components of immature teratoma. She underwent laparotomy with left salpingo-oophorectomy with right ovarian biopsy, omentectomy, appendectomy with B/L pelvic lymphadenectomy. Histopathology was suggestive of grade III immature teratoma. In view of grade III immature teratoma, she received chemotherapy (BEP regimen) post-operatively and is currently under follow up. Conclusion: This case reflects the importance of early diagnosis in cases of pelvic masses in young females. Fertility preservation should be considered in young women with germ cell tumors. Patients with grade II or III tumors or a mere advanced stage disease should be treated with adjuvant chemotherapy (BEP) in addition to surgery.

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Suganuma, Narufumi. "1677a International classification of hrct for occupational and environmental respiratory diseases: describing non-malignant and malignant asbestos related diseases." In 32nd Triennial Congress of the International Commission on Occupational Health (ICOH), Dublin, Ireland, 29th April to 4th May 2018. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/oemed-2018-icohabstracts.1261.

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Kaur, Inderjit, Swarupa Mitra, Manoj Kumar Sharma, Upasna Saxena, Parveen Ahlawat, Amit Kumar Choudhary, Sarthak Tandon, and Prashant Surkar. "Case report of vaginal melanoma." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685371.

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Primary malignant melanoma of vagina is a rare disease with a predilection for local recurrence, distant metastasis and short survival time. Due to the low incidence and lack of reporting in the literature, treatment choices still remain controversial. We describe 2 cases of vaginal malignant melanoma. A 42 yr old female presented with complaints of post coital and per vaginal bleed of 1 month duration. Examination findings show growth 6 cm x 6 cm on anterior vaginal wall, another 3 x 3 cm lesion on right lateral vaginal wall. Vaginal biopsy showed malignant melanoma, S-100 and HMB-45 positive while negative for CK and LCA. MRI Whole abdomen showed altered lesion [3.8cm (AP), 6.0cm (TR) and 4.9cm (CC)] in upper 2/3rd of vagina extending into vaginal fornices and abutting right lower cervix superiorly, right paravaginal extension and mesorectal fascia. No significant enlarged lymph nodes were seen. In view of localised disease she underwent Type III Radical hysterectomy with bilateral salpingo-ophorectomy with bilateral pelvic lymphnode dissection with total vaginectomy. Histopathology s/o 2 tumour nodules, one located in the anterior vaginal cuff measuring – 5 x 5 x 3.2 cm, another located in right lateral vaginal cuff measuring 2.5 x 3 x 1.5 cm, malignant melanoma with involvement of the cervix with full thickness stromal invasion (2.8/2.8 cm,) invading perivaginal soft tissue, distance of invasive carcinoma from closest stromal margin <0.1cm (12 O’ clock), LVI, PNI – not seen, all pelvic LN free (0/25). In view of positive margin and full thickness stromal involvement, she received radiotherapy to pelvis and Inguinal region to a dose of 45 Gy/25# followed by a boost of 16 Gy/8# to the tumour bed till 01/01/16. Another case is a 40 yrs female, presented with complaints of bloody discharge per vaginum of 4 months duration. On examination, there was a large growth occupying the vagina till introitus. Cervix normal, para free. MRI Pelvis showed altered lesion involving left lateral uterine cervix and upper 2/3rd of vagina with full thickness stromal involvement with mild left parametrial, anterior and posterior paravaginal extension, measuring 2.9 x 4.5 x 5.3 cm. Few subcmlymphnodes were seen in bilateral external and internal iliac regions (L>R). Vaginal Biopsy was suggestive of Malignant Melanoma, expressing S-100, HMB 45 and SDX-10. Metastatic work up was negative. She underwent RH with total vaginectomy with bilateral PLND with RPLND. HPR showed exophytic black growth seen involving all quadrants of vagina, extending upwards into both lips of cervix – 7 x 6 x 2.5 cm, Malignant melanoma, distance of invasive carcinoma from closest margin: <0.1 cm (paravaginal soft tissue), 3/8 right Pelvic LN, ECE +, 01/9 Left pelvic LN, ECE absent, 0/6 Right common iliac LN, 0/1 Reperitoneal LN was seen. She received adjuvant radiotherapy to a dose of 50 Gy/25# to the pelvis and inguinals→ boost of 6 Gy/3# to nodal regions showing ECE & 10 Gy/5# to the primary region.

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Kaur, Inderjit. "Case report of vaginal melanoma." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685370.

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Primary malignant melanoma of vagina is a rare disease with a predilection for local recurrence, distant metastasis and short survival time. Due to the low incidence and lack of reporting in the literature, treatment choices still remain controversial. We describe 2 cases of vaginal malignant melanoma. A 42 yr old female presented with complaints of post coital and per vaginal bleed of 1 month duration. Examination findings shows growth 6 cm x 6 cm on anterior vaginal wall, another 3 x 3 cm lesion on right lateral vagianl wall. Vaginal biopsy showed malignant melanoma, S-100 and HMB-45 positive while negative for CK and LCA. MRI Whole abdomen showed altered lesion [3.8 cm (AP), 6.0 cm (TR) and 4.9 cm (CC)] in upper 2/3rd of vagina extending into vaginal fornices and abutting right lower cervix superiorly, right paravaginal extension and mesorectal fascia. No significant enlarged lymph nodes were seen. In view of localised disease she underwent Type III Radical hysterectomy with bilateral salpingo-ophorectomy with bilateral pelvic lymphnode dissection with total vaginectomy. Histopathology s/o 2 tumour nodules, one located in the anterior vaginal cuff measuring – 5 x 5 x 3.2 cm, another located in right lateral vaginal cuff measuring 2.5 x 3 x 1.5 cm, malignant melanoma with involvement of the cervix with full thickness stromal invasion (2.8/2.8 cm,) invading perivaginal soft tissue, distance of invasive carcinoma from closest stromal margin <0.1 cm (12 O’ clock), LVI, PNI – not seen, all pelvic LN free (0/25). In view of positive margin and full thickness stromal involvement, she received radiotherapy to pelvis and Inguinal region to a dose of 45 Gy/25# followed by a boost of 16 Gy/8# to the tumour bed till 01/01/16. Another case is a 40 yrs female, presented with complaints of bloody discharge per vaginum of 4 months duration. On examination, there was a large growth occupying the vagina till introitus. Cervix normal, para free. MRI Pelvis showed altered lesion involving left lateral uterine cervix and upper 2/3rd of vagina with full thickness stromal involvement with mild left parametrial, anterior and posterior paravaginal extension, measuring 2.9 x 4.5 x 5.3 cm. Few subcmlymphnodes were seen in bilateral external and internal iliac regions (L>R). Vaginal Biopsy was suggestive of Malignant Melanoma, expressing S-100, HMB 45 and SDX-10. Metastatic work up was negative. She underwent RH with total vaginectomy with bilateral PLND with RPLND. HPR showed exophytic black growth seen involving all quadrants of vagina, extending upwards into both lips of cervix – 7 x 6 x 2.5 cm, Malignant melanoma, distance of invasive carcinoma from closest margin: <0.1 cm (paravaginal soft tissue), 3/8 right Pelvic LN, ECE +, 01/9 Left pelvic LN, ECE absent, 0/6 Right common iliac LN, 0/1 Reperitoneal LN was seen. She received adjuvant radiotherapy to a dose of 50 Gy/25# to the pelvis and inguinals→ boost of 6 Gy/3# to nodal regions showing ECE & 10Gy/5# to the primary region.

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Grilo, R., C. Scoto Di Fazano, D. Coyral, P. Bertin, C. Bonnet, and R. Treves. "SAT0121 Oral morphine versus oral hydromorphone in rheumatologic non-malignant pain: a prospective randomised study in 144 patients." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.554.

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De Vita, S., C. Scott, M. Fabris, R. Damato, A. Perin, S. Sacco, and GF Ferraccioli. "OP0070 Non-malignant lymphoproliferation in sjoegren’s syndrome: proposed classification based on integrated clinico-phatologic and molecular studies and follow-up." In Annual European Congress of Rheumatology, Annals of the rheumatic diseases ARD July 2001. BMJ Publishing Group Ltd and European League Against Rheumatism, 2001. http://dx.doi.org/10.1136/annrheumdis-2001.330.

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Gupta, Bindiya, Shalini Rajaram, Sandhya Jain, Neerja Goel, and Naveen Tanwar. "Collision tumor of endometrial stromal sarcoma and squamous cell cancer: A rare entity." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685363.

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A collision tumor is defined by the presence of two separate tumors in one organ on gross, microscopic, and immunohistochemical studies and they should be distinguished from malignant mullerian mixed tumors. A 60 year old lady P8L8 presented with blood stained vaginal discharge and post menopausal bleeding. Examination revealed a 1 x 2 cm cervical growth which was reported as squamous cell carcinoma cervix. Imaging revealed myohyperplasia with normal uterine cavity. The patient underwent Type III radical hysterectomy, bilateral salphingo-oophorectomy and bilateral pelvic lymphadenectomy. The uterine corpus revealed 5 cm growth in uterine cavity which was reported as high grade endometrial stromal sarcoma and the cervical growth was non keratinising squamous cell carcinoma infiltrating the former. The lymph nodes, parametria and vaginal cuff were free of tumor. The patient was referred for adjuvant chemotherapy and radiation therapy.

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Bhowmick, Sankha, and John C. Bischof. "Source Terms in Thermal Therapy: A Parametric Study." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2240.

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Abstract Interstitial thermal therapy heats tissues to temperatures exceeding 50°C for a period of seconds to minutes. This technique is currently being investigated as an autonomous therapeutic option for the treatment of benign and malignant diseases at different sites in the body including the prostate, uterine fibroid, kidney and liver (Diller and Ryan, 1998). Some of the interstitial heating techniques that are being studied are microwave, ultrasound (US) and laser. The predominant mechanism of heating associated with each of these techniques appears to be different, i.e. microwave heating is dielectric, US is by mechanical vibration and lasers through photon absorption. Clearly, the thermal distribution in the heated tissue is intrinsically dependent on the mechanism of heating. Since accurate characterization of heat deposition in the tissue is imperative for successful thermal therapy treatments, a broader understanding of the parameters governing the heating or source term(s) is needed.

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Anparasy, S. "Classification of Breast cancer tumors using Feature Selection and CNN." In ERU Symposium 2021. Engineering Research Unit (ERU), University of Moratuwa, 2021. http://dx.doi.org/10.31705/eru.2021.11.

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Breast cancer is one of the most dangerous diseases in the world and almost two million new cases are diagnosed every year. It starts from the breasts tissue and then spreads to other parts of the body. Early detection of breast cancer is important to save the life of a woman as it is related with a risen number of available treatment options. Benign and malignant are the major types of tumors and they are cancerous and non-cancerous, respectively. Benign is not dangerous since it does not destroy the nearby tissues and cannot spread or grow. Malignant tumor invades neighbouring tissues, blood vessels and spreads to other parts of the body by metastasis. Therefore, differentiating malignant from benign will help to detect breast cancer in its early stage. Nowadays, machine learning techniques are used to classify the tumor types hence the quality of lift is increased.

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Eldor, A., M. Bar-Ner, L. Wasserman, Y. matzner, Z. Fuks, and I. Viodavsky. "HEPARIN AND NON-ANTICOAGULANT HEPARINS INHIBIT HEPARANASE ACTIVITY IN NORMAL AND MALIGNANT CELLS:POSSIBLE THERAPEUTIC USE IN PREVENTION OF EXTRAVASATION AND DISSEMINATION OF BLOOD BORNE CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643664.

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Degradation of vascular subendothelium occurs in_vivo during the process of inflammation and tumor invasion. Various observations suggest that the capacity of some blood-borne cells to extravasate may depend in part on their ability to express hepara-nase activity. Incubation of human platelets, human nc-utrophils, or highly metastatic mouse lymphoma cells with sulfate-labeled extracellular matrix (ECM) results in heparanase mediated release of labeled heparan sulfate cleavage fragments (0.5<Kav<0.85 on Sepharose 5B) (J. Clin.Invest. 74: 1842 and 76: 1306; Cancer Res. 43: 2704). The present study was undertaken to test the heparanase inhibitory effect of heparin and non-anticoagulant species of heparin that might havea potential therapeutic use in preventing heparanase mediated extravasation ofblood-borne cells. We prepared totallyor N-desulfated heparins which were either left with their N-position exposed or were subsequently N-acetylated or N-resulfated. These heparins exhibited less than 5% of the anticoagulant activityof native heparin. It was found that total desulfation of heparin abolished its heparanase inhibitory activity whether desulfation was followed by N-acetylation or not. Inhibitory effect was restored by resulfation of the N-position. When only the N-sulfate group was desulfated, inhibitory activity was lost but could be restored by acetylation of the N-position. These results indicate that N-sulfate groups of heparin are necessary for its heparanase inhibitory activity but can be substituted by an acetyl group provided that the 0-sulfate groups are retained. Low Mr heparins (main Mr species of 2500 and 4500 daltons) and heparin fragments as small as the tetrasaccharide inhibited degradation of heparan sulfate in the ECM, albeit to a lower extent than native heparin. Similar effects of the different heparins were observed with heparanase activities from platelets, neutrophils and lymphoma cells. Preliminary in vivo experiments suggest that non-anticoagulant heparins interfere with tumor metastasis and experimental autoimmune diseases (some heparins were kindly provided by Inst. Choay, Paris and Kabi Vitrum, Stockholm).

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Звіти організацій з теми "Non malignant uterine diseases"

Spencer, Thomas E., Elisha Gootwine, Arieh Gertler, and Fuller W. Bazer. Placental lactogen enhances production efficiency in sheep. United States Department of Agriculture, December 2005. http://dx.doi.org/10.32747/2005.7586543.bard.

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The key objectives of this BARD project were to: (1) study long-term effects of immunization of prepubertal ewes against recombinant ovine placental lactogen (roPL) on subsequent birth weights of their lambs and their milk production; (2) optimize the anti-roPL immunization protocol using adjuvant preparations acceptable to producers and regulatory agencies; and (3) determine the physiological mechanism(s) whereby immunization against oPL increases fetal growth and development and mammogenesis. These objectives were based on key findings from a previous BARD project that: (a) immunization of ewes against roPL increased lamb birth weight and ewe milk production during lactation; (b) roPL and recombinant ovine growth hormone (roGH) increased the proliferation and differentiated function of endometrial glands that, in turn, would enhance uterine secretions necessary for fetal and placental growth; and (c) exogenous roPL and roGH stimulated mammogenesis and milk production during lactation. The BARD projects address central problems in sheep production, including reproductive failure due to embryonic/fetal mortality, low birth weight of lambs especially in prolific breeds, and reduced milk yields which affect neonatal survival. The sheep placenta secretes both lactogenic (oPL) and somatogenic (oGH) hormones. The receptors for those hormones are present in the fetus and placenta as well as maternal uterus, and mammary gland. Our research has focused on determining the biological role of these placental hormones in development and differentiation of the uterus during gestation and the mammary gland during pregnancy and lactation. Studies conducted in the current BARD project indicated that the effects of anti-roPL immunization were variable in ewes and that commercially available and widely acceptable adjuvant preparations were not effective to produce high anti-roPL titers in pre-pubertal ewes. In the non-prolific Rambouillet ewe in Texas and in the Awassi and the Assaf in Israel, anti-roPL immunization increased lamb birth weight; however, the magnitude of this effect and the inherent variability precluded our ability to determine the physiological mechanism of how the immunization increases fetal growth. Collectively, our findings suggest that anti-roPL immunization is not currently feasible as an easy and efficacious tool for the producer to increase flock reproductive and production efficiency. The variability in response of individual ewes to anti-roPL immunization likely includes modifying the recombinant hormone and the type of adjuvant used for the immunization. In particular, the oPL may need to be modified to ensure maximum antigenicity in a broad range of breed types. Nonetheless, the investigators continue to collaborate on identifying fundamental mechanisms that can be improved by genetics or management to enhance the efficiency of uteroplacental function and, in turn, fetal growth and development. High prolificacy is a desirable trait in intensive sheep production systems. One of the main limitations of using prolific breeds of sheep is that increased litter size is associated with low birth weights and increased mortality of lambs. Further, low birth weight is associated with an increased propensity for adult diseases and decreased production efficiency. Indeed, our recent studies find that the birth weights of lambs born in large litters can be improved by both genetics and management. Future cooperative research will continue to focus on reproductive efficiency of sheep that have broader implications for improving production efficiency in all types of ruminant livestock.

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