Готові списки джерел за темами / NANO BIOACTIVE GLASS

Добірка наукової літератури з теми "NANO BIOACTIVE GLASS"

Автор: Grafiati

Опубліковано: 11 вересня 2023

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Статті в журналах з теми "NANO BIOACTIVE GLASS"

Odermatt, Reto, Matej Par, Dirk Mohn, Daniel B. Wiedemeier, Thomas Attin, and Tobias T. Tauböck. "Bioactivity and Physico-Chemical Properties of Dental Composites Functionalized with Nano- vs. Micro-Sized Bioactive Glass." Journal of Clinical Medicine 9, no. 3 (March 12, 2020): 772. http://dx.doi.org/10.3390/jcm9030772.

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Bioactive resin composites can contribute to the prevention of secondary caries, which is one of the main reasons for failure of contemporary dental restorations. This study investigated the effect of particle size of bioactive glass 45S5 on chemical and physical composite properties. Four experimental composites were prepared by admixing the following fillers into a commercial flowable composite: (1) 15 wt% of micro-sized bioactive glass, (2) 15 wt% of nano-sized bioactive glass, (3) a combination of micro- (7.5 wt%) and nano-sized (7.5 wt%) bioactive glass, and (4) 15 wt% of micro-sized inert barium glass. Hydroxyapatite precipitation and pH rise in phosphate-buffered saline were evaluated during 28 days. Degree of conversion and Knoop microhardness were measured 24 h after specimen preparation and after 28 days of phosphate-buffered saline immersion. Data were analyzed using non-parametric statistics (Kruskal–Wallis and Wilcoxon tests) at an overall level of significance of 5%. Downsizing the bioactive glass particles from micro- to nano-size considerably improved their capability to increase pH. The effect of nano-sized bioactive glass on degree of conversion and Knoop microhardness was similar to that of micro-sized bioactive glass. Composites containing nano-sized bioactive glass formed a more uniform hydroxyapatite layer after phosphate-buffered saline immersion than composites containing exclusively micro-sized particles. Partial replacement of nano- by micro-sized bioactive glass in the hybrid composite did not impair its reactivity, degree of conversion (p > 0.05), and Knoop microhardness (p > 0.05). It is concluded that downsizing bioactive glass particles to nano-size improves the alkalizing potential of experimental composites with no negative effects on their fundamental properties.

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Nabian, Nima, Maedeh Delavar, Mahmood Rabiee, and Mohsen Jahanshahi. "Quenched/unquenched nano bioactive glass-ceramics: Synthesis and in vitro bioactivity evaluation in Ringer’s solution with BSA." Chemical Industry and Chemical Engineering Quarterly 19, no. 2 (2013): 231–39. http://dx.doi.org/10.2298/ciceq120323057n.

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The paper reports the first attempt at changing cooling treatment of synthesizing method in order to investigate its effect on the physical properties of sol-gel derived nano bioactive glass-ceramic in the system 58SiO2-33CaO-9P2O5 (wt.%). We hypothesized that the method of cooling may affect the properties of nano bioactive glass-ceramic. To test this hypothesis, two different method of cooling treatment was applied after calcinations in synthesizing method. Both quenched and unquenched nano bioactive glass-ceramics were soaked in Ringer?s solution with bovine serum albumin (BSA) for bioactivity evaluation. The obtained samples were analyzed for their composition, crystalinity and morphology through X-ray powder diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), surface electron microscope (SEM) and transmission electron microscope (TEM). The SEM images showed that the morphology of nano bioactive glass-ceramics was completely changed by quenching process. Results of in vitro bioactivity evaluation revealed that the unquenched attains faster apatite formation ability than the quenched sample. Other properties of these two morphologically different nano bioactive glass-ceramics were strongly discussed.

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Al-Sayed, Fatema Aziz, Radwa Hamed Hegazy, Zeinab Amin Salem, and Hanan Hassan El-Beheiry. "COMBINED USE OF HYALURONIC ACID WITH NANO-BIOACTIVE GLASS ENHANCED BIOCEMENT BASED SILICATE STIMULATED BONE REGENERATIVE CAPACITY IN TIBIAL BONE DEFECTS OF RABBITS: IN-VIVO STUDY." Journal of Experimental Biology and Agricultural Sciences 9, no. 5 (October 30, 2021): 630–38. http://dx.doi.org/10.18006/2021.9(5).630.638.

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An ideal biomaterial for bone regeneration is a longstanding quest nowadays. This study aimed to evaluate the osteogenic potentiality of nano-bioactive glass enhanced biocement based silicate with or without hyaluronic acid seeded in rabbits’ tibial bone defects. For this, 24 male rabbits with two 5 mm defects (1 defect per tibia) were divided into three equal groups. Among the predefined three groups, for the rabbits of group 1(control) bone defects were left untreated while for the members of group 2 defects received nano-bioactive glass enhanced biocement based silicate cement, and group 3 defects received nano-bioactive glass cement mixed with hyaluronic acid. Animals of each group were divided equally for euthanization after 3 and 6 weeks. Bone specimens were processed and examined histologically with histomorphometrically analysis of new bone area percentage. The bone defects in group 3 showed significantly improved osseous healing histologically as compared to the group 1&2. The morphometric analysis also revealed a significant increase in the new bone area percentage in group 3 as compared to the group 1 and 2 (P < 0.05). The results of the present study can be concluded that bone defects could be treated with nano-bioactive glass and hyaluronic acid cement. Although, nano-bioactive glass alone was capable of bone regeneration the combination of both had significant regenerative capacity.

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Anitha, D. R., and P. Jayashri. "Nano Structured Bioactive Glass on Dental Disease." Indian Journal of Public Health Research & Development 10, no. 11 (2019): 3459. http://dx.doi.org/10.5958/0976-5506.2019.04118.4.

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Nawaz, Qaisar, Araceli de Pablos-Martín, Lutz Berthold, Juliana Martins de Souza e Silva, Katrin Hurle, and Aldo R. Boccaccini. "Mapping the elemental and crystalline phase distribution in Cu²⁺ doped 45S5 bioactive glass upon crystallization." CrystEngComm 24, no. 2 (2022): 284–93. http://dx.doi.org/10.1039/d1ce01160j.

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Nano-CT and TEM imaging characterisation of Cu-doped 45S5 glass-ceramics. The grain size and content of Cu-riched glassy phase, which affect bioactive and mechanical responses, can be tuned by heat treatment.

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Waltimo, T., T. J. Brunner, M. Vollenweider, W. J. Stark, and M. Zehnder. "Antimicrobial Effect of Nanometric Bioactive Glass 45S5." Journal of Dental Research 86, no. 8 (August 2007): 754–57. http://dx.doi.org/10.1177/154405910708600813.

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Most recent advances in nanomaterials fabrication have given access to complex materials such as SiO2-Na2O-CaO-P2O5 bioactive glasses in the form of amorphous nanoparticles of 20- to 60-nm size. The clinically interesting antimicrobial properties of commercially available, micron-sized bioactive glass 45S5 have been attributed to the continuous liberation of alkaline species during application. Here, we tested the hypothesis that, based on its more than ten-fold higher specific surface area, nanometric bioactive glass releases more alkaline species, and consequently displays a stronger antimicrobial effect, than the currently applied micron-sized material. Ionic dissolution profiles were monitored in simulated body fluid. Antimicrobial efficacy was assessed against clinical isolates of enterococci from persisting root canal infections. The shift from micron- to nano-sized treatment materials afforded a ten-fold increase in silica release and solution pH elevation by more than three units. Furthermore, the killing efficacy was substantially higher with the new material against all tested strains.

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Aguilar-Pérez, Fernando J., Rossana F. Vargas-Coronado, Jose M. Cervantes-Uc, Juan V. Cauich-Rodríguez, Cristian Covarrubias, and Merhdad Pedram-Yazdani. "Preparation and bioactive properties of nano bioactive glass and segmented polyurethane composites." Journal of Biomaterials Applications 30, no. 9 (January 14, 2016): 1362–72. http://dx.doi.org/10.1177/0885328215626361.

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Rocton, N., H. Oudadesse, S. Mosbahi, L. Bunetel, P. Pellen-Mussi, and B. Lefeuvre. "Study of nano bioactive glass for use as bone biomaterial comparison with micro bioactive glass behaviour." IOP Conference Series: Materials Science and Engineering 628 (October 8, 2019): 012005. http://dx.doi.org/10.1088/1757-899x/628/1/012005.

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Moawad, H. M. M., and H. Jain. "Development of nano-macroporous soda-lime phosphofluorosilicate bioactive glass and glass-ceramics." Journal of Materials Science: Materials in Medicine 20, no. 7 (February 28, 2009): 1409–18. http://dx.doi.org/10.1007/s10856-009-3711-7.

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Sarmast Sh, M., S. George, A. B. Dayang Radiah, D. Hoey, N. Abdullah, and S. Kamarudin. "Synthesis of bioactive glass using cellulose nano fibre template." Journal of the Mechanical Behavior of Biomedical Materials 130 (June 2022): 105174. http://dx.doi.org/10.1016/j.jmbbm.2022.105174.

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Більше джерел

Дисертації з теми "NANO BIOACTIVE GLASS"

Ravarian, Roya. "The Effect of Nano-Scale Interaction on the Physico-Chemical Properties of Polymer-Bioactive Glass Composites." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10147.

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Polymer-bioglass composites are favourable materials for bone repair. However, early failure in the interface of components is a common problem in physical mixtures. The aim of this project was to address the issue of phase separation by creating a hybrid material in which the polymer is bonded to bioglass. Synthetic non-biodegradable poly(methyl methacrylate) (PMMA) and natural biodegradable chitosan were selected as two types of polymers for fabrication of hybrid with bioglass. PMMA and chitosan were functionalised with appropriate silane coupling agents and covalently bonded to bioglass. The polymer and bioglass were then co-condensed during sol-gel method to form hybrid. The results of molecular scale analyses demonstrated that at optimum condition (0.1 coupling agent:MMA mol ratio, 60:40 vol% polymer:bioglass), the covalent bond between PMMA and bioglass occurred and resulted in the fabrication of hybrid. The presence of nano-scale interaction resulted in improved physico-chemical and biological properties compared with physical mixtures and bioglass. Furthermore, by manipulating process parameters such as replacing tetrahydrofuran with ethanol, increasing the temperature to 70 °C and adding sodium bicarbonate as catalyst, the gelation time was reduced and a more condensed structure was produced. The chitosan-bioglass hybrid was optimized for the volume ratio of chitosan:bioglass and coupling agent. Furthermore, a new method was developed for the creation of porosity in polymer-bioglass composites in which sodium bicarbonate was used as a gas foaming agent and a biocompatible alternative for the commonly used hydrofluoric acid during sol-gel method. In conclusion, the presence of nano-scale interaction significantly improved the physico-chemical properties of polymer-bioglass hybrids via promoting the homogenous distribution of phases. These hybrids open an avenue for the applications of polymers-bioglass composites for bone replacement and tissue engineering.

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Mabrouk, Mohamed Mostafa. "Preparation of PVA / Bioactive Glass nanocomposite scaffolds : in vitro studies for applications as biomaterials : association with active molecule." Thesis, Rennes 1, 2014. http://www.theses.fr/2014REN1S063/document.

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Le Poly Vinyl Alcohol (PVA) a été associé aux verres élaborés dans un système quaternaire (BG) 46S6 par les procédés cités (fusion, sol-gel et sacffolds). Différents paramètres intervenant dans les synthèses des verres bioactifs ont été étudiés, nous citons à titre d’exemple : la température, le pH, la taille des particules, le rapport Polymère / verres, la microstructure, la porosité et la biodégradation. Les caractéristiques thermiques des verres élaborés ont été également déterminées après chaque synthèse par analyse thermique différentielle (DSC/TG, DTA/TG). Ainsi, la température de fusion, la température de transition vitreuse et la température de cristallisation ont été élucidées. Ces caractéristiques thermiques changent lorsque la composition chimique du verre est modifiée. A ce titre, les compositions chimiques ont été étudiées par Fluorescence (XRF) et Inductively Coupled Plasma-Opticale Emission Spectroscopy (ICP-OES) après chaque synthèse pour s’assurer de la pureté des verres bioactifs élaborés et destinés à des applications médicales. Plusieurs techniques physico chimiques d’analyses (DRX, MEB, MET, FT-IR, XRF, ICPOES) ont été mises en oeuvre pour déterminer les propriétés physico chimiques de nos verres bioactifs avant et après expérimentations « in vitro ». Le nano composite Polymère-Verres scaffolds que nous avons obtenu présente des particules de tailles comprises entre 40 et 61 nm et une porosité d’environ 85%. La biodégradation des verres scaffolds décroît lorsque la teneur en verre scaffolds dans le nano composite croît. Les expérimentations « in vitro » montrent qu’après immersion de ces nano composites dans un liquide physiologique synthétique (SBF), une couche d’apatite (phosphate de calcium) se forme à leur surface. L’épaisseur de la couche formée dépend clairement de la taille des particules et du rapport polymère / verre scaffolds
The aim of the present work is the preparation of Bioactive Glass (BG) 46S6 by different techniques. Fabrication of composite scaffolds by using of Poly Vinyl Alcohol (PVA) and quaternary BG (two methods melting and sol-gel) with different ratios to the prepared scaffolds was carried out. Different factor affecting the final properties of the prepared composite scaffolds were investigated in this study, such as; temperature of treatment, BG particle size, polymer/glass ratio, microstructure, porosity, biodegradation, bioactivity, and drug release. The thermal behavior of the prepared bioactive glass by sol-gel and melting techniques were identified using Differential Scanning Calorimetric/Thermo Gravimetric (DSC/TG) or Differential Thermal Analysis/Thermo Gravimetric (DTA /TG). The elemental composition of the prepared bioactive glasses was determined by X-rays Fluorescence (XRF) to confirm that the prepared bioactive glasses have the same elemental compositions and high purity for biomedical applications. The particle size of the prepared bioactive glass was determined by Transmission Electron Microscopic (TEM). Nano-bioactive glass could be obtained by modified sol-gel and the obtained particle size ranged between 40 to 61 nm. The prepared bioactive glass by both applied methods has the same amorphous phase and all identified groups as well as. The porous scaffold has 85% porosity with a slight decrease by increasing the glass contents. The degradation rate decreased by increasing of glass content in the prepared scaffolds. The bioactivity of the prepared composite scaffolds was evaluated by XRD, FTIR, SEM coupled with EDX and Inductively Coupled Plasma-Optical Emission Spectroscopic (ICP-OES). It has been observed that after soaking in Simulated Body Fluid (SBF), there was an apatite layer formed on the surface of the prepared samples with different thickness depending on the glass particle size and polymer/glass ratio

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RAI, PRAGYA. "MECHANICAL STUDIES ON NANO BIOACTIVE GLASS EMBEDDED GELATIN-PECTIN NANOFIBERS." Thesis, 2017. http://dspace.dtu.ac.in:8080/jspui/handle/repository/15930.

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Ultrafine fibers and fibrous mats are produced by electrospinning of aqueous solution of Gelatin and Pectin. The process used in this method avoids the use of synthetic polymer or non aqueous solution for making the fibers by using the natural polymers. Pectin is polyelectrolyte in nature that’s why the electrospinning of pectin was not possible. Earlier the blends of pectin and poly (ethyleneoxide) (PEO) were for electrospinning for making ultrafine pectin fibers. The main aim of my investigation is to search for the alternatives of the PEO for electrospinning of proteins and polysaccharides. On performing electrospinning by using only pectin electro spraying occurs, no fiber formation takes place. So there is need of some carrier polymers so that jet formation of pectin starts. So in the process of making the pectin fibers gelatin with formic acid is used as a carrier polymer. Then bioactive glass solution is used in the aqueous solution of gelatin and pectin. The parameters of electrospinning are optimized so that formation of fibers takes place. When all the parameters are optimized then drug, vitamin-D precursor has been loaded and its release is performed in PBS. The various characterization of the fibers are done like SEM, FTIR, TGA, tensile testing for mechanical properties. The SEM results shows the fiber structure of pectin, gelatin, gelatin-pectin, gelatin-pectin-BG which shows that nanofibers are formed. The tensile strength increases when pectin is added and further increases when BG is added. FTIR shows the peaks of various functional groups present in the fiber.

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Rodrigues, José Miguel Botica. "Production and characterization of magnetic bioactive glass membranes." Master's thesis, 2019. http://hdl.handle.net/10362/80557.

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Bone cancer treatment usually originates bone defects with residual tumour cells that can proliferate during bone regeneration. Therefore, a scaffold for bone regeneration that simultaneously kill residual tumour cells is needed. This project aims at producing a composite system composed of a bioactive glass (BAG) and magnetic nanoparticles (MNPs). This system is highly bioactive and reabsorbable due to the bioactive glass which leads to formation of a hydroxyapatite (HA) layer that bonds to bone. The system is biodegradable at an adequate rate for bone regeneration. Magnetic nanoparticles act as thermoseeds generating clinically relevant heat under an applied alternating magnetic field to kill or sensitize tumour cells. In combination with release of an anticancer drug, this composite system will effectively kill bone tumour cells whilst providing a base for bone regeneration. BAG was produced by a simple sol-gel technique assisted by EISA (Evaporation Induced Self-Assembly). Ball milling equipment was used to decrease the BAG particle size and increase its dispersibility. The powders were characterized by SEM (scanning electron microscopy), EDS (energy dispersive x-ray spectroscopy), and FTIR (Fourier Transform Infrared Spectroscopy). IONPs were produced through chemical co-precipitation and coated with oleic acid to avoid aggregation and loss of superparamagnetic properties over time. First, PVP/BAG composite membranes were produced by electrospinning and the parameters were optimized to produce smaller fibres as it translates into higher surface area and higher bioactivity. IONPs were then incorporated in the solution. The electrospun membranes were crosslinked due to the PVP water-soluble characteristic. UV and thermal crosslinking were employed, but only thermal crosslinking proved to be successful. For this to be successful TGA/DSC was helpful to find the crosslinking temperature and provided information about the thermal stability of the membranes. Water-insoluble membranes were tested for magnetic hyperthermia application and cytotoxicity assays were also performed. The IONPs proved to have superparamagnetic properties and a small temperature variation was achieved for a 10 mg membrane sample, which proved the potential of composite membranes for this application.

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Murty, Hara Prasad. "Development of Porous Bioactive SiO2-Na2O-CaO-P2O5 Glass Ceramic Scaffold." Thesis, 2012. http://ethesis.nitrkl.ac.in/3628/1/Hara_Prasad_Murty.pdf.

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Bioactive glasses of chemical composition 48.4SiO2 -23.8Na2O- 23.8CaO- 4.0P2O5 wt% was prepared through Sol-Gel route. It was then crystallized through thermal treatment. Porous samples of the mentioned composition using Naphthalene (0, 30, and 50 weight percentage) as pore former were made and tested for Bulk Density, Apparent porosity, Linear Shrinkage, Cold Crushing Strength, and Bi-axial flexural strength. Maximum porosity of 50% was obtained by this process. The maximum value of CCS obtained was 7.8MPa without any pore former and a minimum of 2.3 MPa for 50% Naphthalene. The Bi-axial flexural strength varied between the extremes of 16.3 MPa and 5.6 MPa. Their pore size distribution was also studied to ensure the presence of pores with size greater than 100 µm, which happens to be the critical lower limit for Angiogenesis. Samples were also prepared with a radial porosity gradient similar to the structure of the cancellous part of the Bone structure. The samples contained a central core of higher porosity and a outer concentric ring of lower porosity. These samples were also tested for the above mentioned mechanical properties. The Bioactivity of the samples was also studied by immersing them in a SBF solution for a period of 1, 3, and 7 days. These samples were then studied using XRD, SEM, EDX, and FTIR and showed significant formation of HCA ensuring their Bioactivity.

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Частини книг з теми "NANO BIOACTIVE GLASS"

Moawad, Hassan M. M., and Himanshu Jain. "Fabrication of Nano-Macro Porous Soda-Lime Phosphosilicate Bioactive Glass by the Melt-Quench Method." In Progress in Nanotechnology, 17–31. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9780470588260.ch4.

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Moawad, Hassan M. M., and Himanshu Jain. "Creation of Nano-Macro-lnterconnected Porosity in a Bioactive Glass-Ceramic by the Melt-Quench-Heat-Etch Method." In Progress in Nanotechnology, 45–47. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9780470588260.ch7.

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Massera, Jonathan. "Bioactive glass-ceramics: From macro to nano." In Nanostructured Biomaterials for Regenerative Medicine, 275–92. Elsevier, 2020. http://dx.doi.org/10.1016/b978-0-08-102594-9.00010-3.

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Saiz, E., S. Lopez-Esteban, S. Fujino, T. Oku, K. Suganuma, and A. P. Tomsia. "CHARACTERIZATION OF METAL/GLASS INTERFACES IN BIOACTIVE GLASS COATINGS ON Ti-6Al-4V AND Co-Cr ALLOYS." In Nano and Microstructural Design of Advanced Materials, 61–67. Elsevier, 2003. http://dx.doi.org/10.1016/b978-008044373-7/50034-6.

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Bin Zafar Auniq, Reedwan, Namon Hirun, and Upsorn Boonyang. "Three-Dimensionally Ordered Macroporous-Mesoporous Bioactive Glass Ceramics for Drug Delivery Capacity and Evaluation of Drug Release." In Ceramic Materials [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.95290.

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Bioactive glass ceramics (BGCs) have been used in orthopedic and dentistry due to having better osteoconductive and osteostimulative properties. This study aimed to evaluate and compare the drug release properties of two different BGCs; 45S5 and S53P4. The BGCs were composed with four phases of SiO2 – CaO – Na2O – P2O5 system, synthesized by sol–gel method using dual templates; a block-copolymer as mesoporous templates and polymer colloidal crystals as macroporous templates, called three-dimensionally ordered macroporous-mesoporous bioactive glass ceramics (3DOM-MBGCs). In vitro bioactivity test performed by soaking the 3DOM-MBGCs in simulated body fluid (SBF) at 37°C. The results indicated that, the 45S5 have the ability to grow hydroxyapatite-like layer on the surfaces faster than S53P4. Gentamicin drug was used to examine in vitro drug release properties in phosphate buffer solution (PBS). The amount of drug release was quantified through UV/Vis spectroscopy by using o-phthaldialdehyde reagent. S53P4 showed high drug loading content. The outcome of drug release in PBS showed that both S53P4 and 45S5 exhibited a slowly continuous gentamicin release. The resultant drug release profiles were fitted to the Peppas-Korsmeyer model to establish the predominant drug release mechanisms, which revealed that the kinetics of drug release from the glasses mostly dominated by Fickian diffusion mechanism.

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Тези доповідей конференцій з теми "NANO BIOACTIVE GLASS"

Batra, Uma, Seema Kapoor, J. D. Sharma, S. K. Tripathi, Keya Dharamvir, Ranjan Kumar, and G. S. S. Saini. "Nano-Hydroxyapatite∕Fluoridated and Unfluoridated Bioactive Glass Composites: Structural Analysis and Bioactivity Evaluation." In INTERNATIONAL CONFERENCE ON ADVANCES IN CONDENSED AND NANO MATERIALS (ICACNM-2011). AIP, 2011. http://dx.doi.org/10.1063/1.3653714.

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Dixit, K., and N. Sinha. "Additively Manufactured Nanofiber Reinforced Bioactive Glass Based Functionally Graded Scaffolds for Bone Tissue Engineering." In 2019 IEEE 13th International Conference on Nano/Molecular Medicine & Engineering (NANOMED). IEEE, 2019. http://dx.doi.org/10.1109/nanomed49242.2019.9130605.

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Aniket and Ahmed R. El-Ghannam. "Zeta Potential of Silica Calcium Phosphate Nanocomposite: Effect of Material Composition and Medium pH." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192883.

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Biodegradable ceramics have lately found exciting applications in orthopedic and maxillofacial surgeries as agents for bone repair, drug delivery vehicles and filling materials. A novel bioactive resorbable ceramic that demonstrated a superior mechanical properties, bioactivity and resorbability compared to traditional calcium phosphate ceramics or bioactive glass is bioactive silica-calcium phosphate nanocomposite (SCPC) [1, 2]. Previous studies have demonstrated that the enhanced bioactivity of SCPC is attributed to its nano structure as well as other physicochemical properties of the material [2]. Surface charge is one of the most important factors that control tissue and cell response to the implant material. Additionally, surface charge enhances the adsorption of biological molecules onto the material surface. The objective of the present work is to investigate the effect of SCPC composition and medium pH on the zeta potential and conductance of the material.

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Liu, Xueran, and Ahmed R. El-Ghannam. "Effect of Processing Parameters on the Microstructure and Mechanical Behaviour of Nano Bioceramic." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193076.

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Silica-calcium phosphate nanocomposite (SCPC) has a superior bone regenerative capacity and resorbability when compared to hydroxyapatie (HA) and bioactive glass [1–2]. Synthesis of SCPC bioceramics with superior mechanical properties has been an important and challenging issue. Ideally, the mechanical strength of the orthopedic implantat should be comparable to that of the host-bone in order to provide structural support and minimize stress shielding. The compressive strength of trabecular bone ranges from 2–12 MPa and that of cortical bone varies in the range of 100–230 MPa [3]. The aim of the present study is to study the effect of processing parameters on the mechanical properties of SCPC cylinders prepared by powder metallurgy technique. The mechanical properties were correlated to the microstructure of SCPC prepared under different processing conditions.

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Wetaify, Ahmed Rajih Hassan, Firas Fouad Abdullah, and Safaa Hashim Radhi. "Enhancement of bioactive glass ceramic using magnesium nano rod addition: (B. A. G. C / Mg NRs nanocomposite materials for bone repairing)." In 2ND INTERNATIONAL CONFERENCE ON MATERIALS ENGINEERING & SCIENCE (IConMEAS 2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0000460.

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Ducheyne, Paul, Hongxia Gao, Ahmed El-Ghannam, Irving Shapiro, and Portonovo Ayyaswamy. "The Use of Bioactive Glass Particles As Microcarriers." In ASME 1996 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/imece1996-1192.

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Abstract Among the various materials that affect bone cell function, and therefore, could serve as the microcarrier material, bioactive glass has been our material of choice. In the early seventies, Hench et al.[1] formulated these glasses with a typical composition of 45% SiO2, 24.5% Na2O, 24.5% CaO and 6% P2O5 (by weight). They documented that upon implantation in bone tissue, this glass called bioactive glass 45S5, firmly adhered to bone. By now, at least nine groups from around the world have shown that glasses typically containing 40–60 mole % SiO2 and various amounts of Na2O, CaO, P2O5 and some smaller amounts of other oxides bond to bone tissue. As the glass is immersed in vivo, bodily fluids cause the glass to corrode. This corrosion results in selective leaching of sodium ions, the formation of a silica gel layer, and eventually the formation of a calcium phosphate rich layer. It is a recent finding that bioactive glass, when made in granular form with a narrow size range (300–355 μm), has the unique capacity to cause differentiation of osteoprogenitor cells to cells expressing the osteoblastic phenotype [2]. This property of upregulating stromal osteoprogenitor cells to osteoblasts in vivo, as well as the capacity to enhance the expression of the osteoblastic phenotype in vitro, form the basis for our selection of bioactive glass 45S5 as the carrier of choice for culturing typical bone tissue cells in microgravity environment.

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Rojas, O., M. Prudent, M. E. López, F. Vargas, and H. Ageorges. "Study of Atmospheric Plasma Parameters for Denser Bioactive Glass Coatings." In ITSC2019, edited by F. Azarmi, K. Balani, H. Koivuluoto, Y. Lau, H. Li, K. Shinoda, F. Toma, J. Veilleux, and C. Widener. ASM International, 2019. http://dx.doi.org/10.31399/asm.cp.itsc2019p0872.

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Abstract This study assesses the influence of atmospheric plasma spraying parameters on splat stacking and porosity formation in bioglass coatings prepared from commercial powders. Coating samples were deposited on stainless steel substrates using spraying parameters established through numerical simulations. Different Ar-H2 mixtures were used as the forming gas, and plasma current and spraying distance were varied. Coating microstructure and phase composition were determined by SEM and XRD analysis. Although numerical simulations for each parameter set predicted a suitable Sommerfeld number for proper splat stacking, Na2O and P2O5 volatilization occurred during spraying, promoting the formation of porosity in the coatings. Denser coatings were obtained, however, by adjusting the gas mixture ratio, plasma current, and spraying distance such that enthalpy of the plasma jet is sufficient to overcome the glass transition temperature of the powder and at the same time avoid the evaporation of volatile oxides.

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Yatongchai, Chokchai, Mark R. Towler, and Anthony W. Wren. "An Investigation into the Structure and Properties of CaO-ZnO-SiO2-TiO2-Na2O Bioactive Glass/Hydroxyapatite Composite." In 2013 39th Annual Northeast Bioengineering Conference (NEBEC). IEEE, 2013. http://dx.doi.org/10.1109/nebec.2013.51.

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