Дисертації з теми "Musculoskeletal system Diseases Diagnosis"
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Chan, Cho-cheong, and 陳楚莊. "Magnetic resonance elastography: neuronal andmuscular studies, and a novel acoustic shear wave generator." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B38643868.
Повний текст джерелаMendonça, José Alexandre 1969. "O ultrassom articular = uma ferramenta importante de avaliação no diagnóstico na artrite reumatóide inicial." [s.n.], 2011. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310630.
Повний текст джерелаTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
Made available in DSpace on 2018-08-18T22:39:29Z (GMT). No. of bitstreams: 1 Mendonca_JoseAlexandre_D.pdf: 2535796 bytes, checksum: 374639057a45bad9800020693b3bc4de (MD5) Previous issue date: 2011
Resumo: Objetivo: Avaliar sinovite pelo ultrassom (US) articular em pacientes com artrite reumatóide (AR) inicial e correlacionar com os dados clínicos, radiográficos e laboratoriais. Pacientes e Métodos: Este estudo avaliou 832 articulações de 32 pacientes (24 mulheres e 8 homens) com AR inicial selecionados no período de 2008 a 2010 do ambulatório de artrite da Universidade Estadual de Campinas, caracterizado por 20 (62.5%) caucasóides e 12 (37.5%) não caucasóides; um tempo médio de doença de 13 meses, com média de idade de 42 anos. Nesta amostra foram detectadas, pelas escalas semiquantitativas cinza (SG) e pelo power Doppler (PD), 173 articulações com sinovite de grau 0 a 3. Foi usado um ultrassom GE LOGIQ XP-linear de alta frequência (8-10 MHz). Todas as mãos foram radiografadas e analisadas pelo score de Larsen com variação de grau entre 0 a V. Resultados: Este estudo evidenciou correlações significativas e positivas entre os dados ultrassonográficos, clínicos e laboratoriais: SGUS e PDUS do punho D e PCR (r=0.41 a 0.42), SGUS do 3ªMTF D, 4ªMTF D com o HAQ - DI (r=0.37 a 0.38), SGUS do 4ªMTF E e o PCR (r=0.42), SGUS do 2ªMTF D e o FR (r=0.40), SGUS-Score 7mod com o DAS28 (PCR) (r=0.38) e o PDUS-Score 7mod com o PCR (r=0.39). Houve correlações significativas negativas com o SGUS 2ªMTCF D com a dose e o tempo de uso MTX (r=-0.36 a -0.37). O PCR nesta amostra pode ser considerado um indicador de atividade inflamatória quando existe sinovite detectada pelo US. Conclusão: A utilização do US mostrou ser uma importante ferramenta na avaliação de AR inicial e dá um suporte mais seguro no diagnóstico para iniciativas terapêuticas mais precisas e seletivas
Abstract: This study evaluated 832 joints of 32 patients (24 women and 8 men) with early RA enrolled for the period 2008 to 2010 of the arthritis clinic of the Universidade Estadual de Campinas (UNICAMP), characterized by 20 (62.5%) Caucasians, 12 (37.5%) non-Caucasians, an average disease was 13 months, with a mean age of 42 years. This sample was detected by semi-quantitative gray scale (GS) and power Doppler (PD) 173 joints with synovitis of degree 0 to 3. It was used a GE LOGIQ XP-linear ultrasound and high frequency (8-10 MHz) transducer. All hands were X-rayed and analyzed by the Larsen score, with grades ranging from 0 to V. This study showed positive and significant correlation between sonographic, clinical and laboratory data: GSUS/PDUS of right wrist and CRP (r = 0.41 to 0.42), GSUS of the right 3ºMTP, GSUS of the right 4ºMTP and HAQ - DI (r = 0.37 to 0.38), GSUS of the left 4ºMTP and CRP (r = 0.42), GSUS of the right 2ºMTP and FR (r = 0.40), GSUS 7mod-score with the DAS28 (CRP) (r = 0.38) and PDUS 7mod-Score to CRP (r = 0.39). There was a significant negative correlation with the right 2ºMCP with dose and duration of MTX use (r = -0.36 to -0.37). The CRP in this sample can be considered an indicator of inflammatory activity, when analyzed separately or with all the joints committed. Using the US was an important tool in the evaluation of RA and gives a more secure support for initiatives in the diagnosis and treatment more precise and selective
Doutorado
Clinica Medica
Doutor em Clínica Médica
Johansson, Jan Å. "Psychosocial factors at work and their relation to musculoskeletal symptoms." Lund : Dept. of Psychology, Göteborg University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39775906.html.
Повний текст джерелаStover, Bert D. "Validation and evaluation of a disability measure for upper extremity musculoskeletal disorder screening in the workplace and prognostic factors of long-term disability /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/5407.
Повний текст джерелаSpielholz, Peregrin. "A comparison of upper extremity physical risk factor measurement methods /." Thesis, Connect to this title online; UW restricted, 1999. http://hdl.handle.net/1773/8468.
Повний текст джерелаRenz, Miriam Christina. "Laboratory investigation of a simulated industrial task pre- and post-ergonomics intervention." Thesis, Rhodes University, 2004. http://hdl.handle.net/10962/d1015806.
Повний текст джерелаLi, Sin Wan. "Development of immunoassays for prognosis and diagnosis of cardiovascular diseases /." View abstract or full-text, 2007. http://library.ust.hk/cgi/db/thesis.pl?CHEM%202007%20LI.
Повний текст джерелаBlosser, Peter, Remil Simon, and Courtney Ridner. "Differential Diagnosis of Pan-Uveitis: Behçet’s Disease." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/asrf/2018/schedule/2.
Повний текст джерелаDillard, E. Margo (Edna Margo). "An Epidemiological Survey of Musculoskeletal Pain Among a Self-Selected Population of Organists." Thesis, University of North Texas, 1998. https://digital.library.unt.edu/ark:/67531/metadc935779/.
Повний текст джерелаHarben, Alan M. "An Electromyographic kinetic model for passive stretch of hypertonic elbow flexors." Diss., Georgia Institute of Technology, 2000. http://hdl.handle.net/1853/20301.
Повний текст джерелаHorwood, Alan C. "Computer diagnosis of tomographic pulmonary images." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324376.
Повний текст джерелаAlzubaidi, Rania S. M. "Fully automated computer system for diagnosis of corneal diseases. Development of image processing technologies for the diagnosis of Acanthamoeba and Fusarium diseases in confocal microscopy images." Thesis, University of Bradford, 2017. http://hdl.handle.net/10454/17142.
Повний текст джерелаAl-Kabir, Zul Waker Mohammad, and N/A. "A Knowledge Based System for Diagnosis of Lung Diseases from Chest X-Ray Images." University of Canberra. Information Sciences & Engineering, 2007. http://erl.canberra.edu.au./public/adt-AUC20070823.160921.
Повний текст джерелаAl-Kabir, Zul Waker Mohammad. "A knowledge based system for diagnosis of lung diseases from chest x-ray images /." Canberra : University of Canberra, 2007. http://erl.canberra.edu.au/public/adt-AUC20070823.160921/index.html.
Повний текст джерелаThesis submitted in fulfilment of the requirements for the degree of Master of Information Science in the School of Information Sciences and Engineering under the Division of Business, Law and Sciences at the University of Canberra, May 2006. Bibliography: leaves 120-132.
Panta, Utsab, Adam chan, and Debalina Das. "Osteonecrosis of Jaw: Common etiologies, uncommon treatments." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/asrf/2019/schedule/201.
Повний текст джерелаCho, Jinsoo. "Velocity-based cardiac segmentation and motion-tracking." Diss., Available online, Georgia Institute of Technology, 2004:, 2003. http://etd.gatech.edu/theses/available/etd-04082004-180106/unrestricted/cho%5Fjinsoo%5F200312%5Fphd.pdf.
Повний текст джерелаTodd, Bryan S. "A formal approach to the design of medical diagnostic programs." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670360.
Повний текст джерелаCamargo, Anyela. "An automatic system for the detection, diagnosis and control of plant diseases and other agents." Thesis, University of Liverpool, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426137.
Повний текст джерелаTan, Zhen. "Low noise heart sound acquisition in wearable system for individual-centered CVD diagnosis." Thesis, University of Macau, 2017. http://umaclib3.umac.mo/record=b3691773.
Повний текст джерелаWeissenfels, Robert. "CCL11 as a Biomarker for the In Vivo Diagnosis of Chronic Traumatic Encephalopathy." Scholarship @ Claremont, 2018. http://scholarship.claremont.edu/cmc_theses/1823.
Повний текст джерелаRoberts, Tim S. "The development of an expert system for the diagnosis of diseases in fibre and dairy goats." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 1990. https://ro.ecu.edu.au/theses/1113.
Повний текст джерелаBrink, Yolandi. "Sitting posture : a predictive factor for upper quadrant musculoskeletal pain in computing high school students." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71876.
Повний текст джерелаIncludes bibliography
ENGLISH ABSTRACT: Introduction: The increased prevalence of adolescent upper quadrant musculoskeletal pain (UQMP) is becoming a great concern to health professionals. The risk factors associated with adolescent UQMP are complex and multifactorial, including, among others sitting as a physical risk factor. However, no evidence exists to support sitting postural angles as a potential predictive factor for adolescent UQMP in computing high school students. Thus, the current project aimed to describe the three-dimensional (3D) sitting postural angles of computing South African high school students in a real-life setting, using a well-tested and documented posture measurement instrument. Methodology: This research project is comprised of seven related studies. Part I of the dissertation presents a systematic review describing the reliability and validity testing of posture measurement instruments. This is followed by three primary correlation and repeated measures observational studies aimed at ascertaining the reliability and validity of a newly developed 3D Posture Analysis Tool (3D-PAT) in the measurement of nine sitting postural angles of computing high school students. Part II of the dissertation presents a systematic review, that evaluates the latest published research evidence of whether sitting is related to UQMP, and, if so, to identify the elements of sitting that significantly contribute to UQMP. This review is followed by a description of a cohort study, with a prospective period of one year. The 3D-PAT was implemented in a clinical research setting in order to measure the 3D sitting posture of a cohort of asymptomatic computing high school students and in order to assess the outcome, seated-related UQMP, prospectively. The prospective study design enabled the research project to contribute to an understanding of any causative relationship between the exposure (sitting postural angles) and the outcome (seated-related UQMP) in a subgroup of adolescents (computer users). Results: After the first phase of psychometric testing of the 3D-PAT using high school students, the findings indicated that the instrument required modifications prior to further psychometric testing. The second phase of testing revealed that the 3D-PAT compared very well with the reference standard for measurement of the X-, Y- and Z-coordinates of the reflective markers on a mannequin. The findings from the phase three study, again using high school students, indicated that the 3D-PAT compared very well with the reference standard and justified its use for the measurement of six sitting postural angles of the upper quadrant in computing high school students. For the cohort study, a 60% response rate for participation was achieved at baseline, with 98% of the students participating at six-month and 80% at one-year follow up. Of the students, 33.5% complained of seated-related UQMP during the follow-up period. Exposure to increased head flexion (>80°) (ρ=0.0001) and the combination of increased head flexion and decreased cranio-cervical angles (ρ=0.007) were significant predictors of seated-related UQMP for those computing high school students complaining of pain greater than the 90th percentile for such. Conclusion: The project described in the current dissertation is the first research project to assess sitting postural angles in asymptomatic high school students, while they worked on desktop computers in a school computer classroom and to assess UQMP prospectively. The research project reports a causal relationship between increased head flexion and seated-related UQMP as increased head flexion was found to be a predictor of seated-related UQMP developing within six to 12 months for computing high school students with a pain score equal or greater than the 90th percentile for pain. The research project emphasises that further research is warranted to investigate the causal pathway between sitting posture and adolescents’ UQMP.
AFRIKAANSE OPSOMMING: Inleiding: Die stygende voorkoms van boonste-kwadrant muskuloskeletale-pyn (BKMP) onder adolessente is besig om ’n groot bron van kommer vir professionele gesondheidswerkers te word. Die risiko-faktore waarmee adolessente BKMP gepaard gaan, is kompleks en multifaktories. Dit sluit onder andere sit as ’n fisiese risiko-faktor in. Daar is egter nog geen bewyse om sittende posturale hoeke as potensiële voorspeller van adolessente BKMP te ondersteun nie. Dus beoog hierdie projek om die drie-dimensionele (3D) sittende posturale hoeke van Suid-Afrikaanse hoërskoolleerders wat ook rekenaargebruikers is, in ’n werklike omgewing te beskryf, deur gebruik te maak van ’n instrument wat postuur meet en wat goed getoets en gedokumenteerd is. Metodiek: Hierdie navorsingsprojek is saamgestel uit sewe studies. Gedeelte I van die proefskrif bied ’n sistematiese oorsig van betroubaarheids- en geldigheidstoetsing van instrumente wat postuur meet. Dit word gevolg deur drie primêre korrelasie studies en studies vir die waarneming van herhaalde meting wat die betroubaarheid en geldigheid van n nuut-ontwikkelde 3D instrument vir posturale analise (3D-PAT) bepaal, wanneer nege sittende posturale hoeke van hoërskoolleerders wat rekenaars gebruik, gemeet word. Gedeelte II van die proefskrif bied ’n sistematiese oorsig van die jongste gepubliseerde navorsing om te evalueer of daar bewyse is dat sit verband hou met BKMP, en, indien wel, om die elemente van sit wat betekenisvol bydra tot BKMP, te identifiseer. Die sistematiese oorsig word deur ’n beskrywing van ‘n jaarlange kohortstudie gevolg. Die 3D-PAT is gebruik in ’n kliniese-navorsingsraamwerk om die 3D-sitpostuur van ’n kohort simptoomvrye hoërskoolleerders wat rekenaargebruikers is, te meet en sitverwante BKMP as uitkoms in die vooruitsig te stel. Die studie ontwerp het dit vir die navorsingsprojek moontlik gemaak om ’n insiggewende bydrae te lewer tot begrip vir enige oorsaaklikheidsverwantskap tussen die blootstelling (sittende posturale hoeke) en die uitkoms (sitverwante BKMP) in ’n subgroup van adolessente (rekenaargebruikers). Resultate: Na afloop van die eerste psigometriese toesting van die 3D-PAT, waarin hoërskoolleerders gebruik is, het bevindings daarop gedui dat die instrument verander moet word voordat toetsing kan voortgaan. Die tweede fase van toetsing het getoon dat die 3D-PAT baie goed vergelyk met die verwysingstandaard vir die meet van die X-, Y- en Z-koördinate van die reflektiewe merkers op ’n mannekyn. Die bevindings van die derde fase van die studie, waartydens hoërskoolleerders weer gebruik is, het aangedui dat die 3D-PAT baie goed vergelyk met die verwysingstandaard. Dit het die gebruik van die instrument om ses sittende posturale hoeke van die boonste kwadrant van hoërskoolleerders wat rekenaars gebruik te meet, bevestig. Die kohortstudie het ’n 60%-reaksiesyfer vir deelname behaal tydens die basislynmetings, waarvan 98% leerders deelgeneem het aan die sesmaande-opvolgmetings en 80% aan die eenjaaropvolgmetings. ’n Totaal van 33.5% van die leerders het gekla van sitverwante BKMP gedurende die eenjaar opvolgperiode. Blootstelling aan ’n vergrootte kopfleksie-hoek (>80°) (ρ = 0.0001) en die kombinasie van ’n vergrootte kopfleksie- en verminderde kranio-servikale hoek (ρ = 0.007) was betekenisvolle voorspellers van sitverwante BKMP vir die hoërskoolleerders wat rekenaars gebruik en kla van groter pyn as die 90ste persentiel daarvan. Gevolgtrekking: Hierdie projek is die eerste navorsing wat sittende posturale hoeke van simptoomvrye hoërskoolleerders wat op tafelrekenaars in die skool se rekenaarklaskamer werk, meet en BKMP voorspel. Die navorsingsprojek rapporteer ‘n oorsaaklikheidsverwantskap tussen ‘n vergrootte kopfleksie-hoek en sitverwante BKMP omdat vergrootte kopfleksie ‘n voorspeller is van sitverwante BKMP wat binne ses tot 12 maande by hoërskoolleerders wat rekenaars gebruik, met ‘n pyntelling gelyk of groter as die 90ste persentiel van pyn, ontwikkel. Die navorsingsprojek beklemtoon dat verdere navorsing om die oorsaaklikheidsroete tussen sitpostuur en adolessente BKMP te ondersoek, geregverdig is.
Medical Research Council of South Africa
National Research Fund
Division of Research Development and Support of Stellenbosch University
Mitchell, Kierra. "Racial Disparities in the Diagnosis and Treatment of Type 1 Diabetes in Black American Youth." Scholarship @ Claremont, 2019. https://scholarship.claremont.edu/scripps_theses/1239.
Повний текст джерелаGuo, Ran. "Intelligent method for collecting vital signals in versatile distributed e-home healthcare." Thesis, University of Macau, 2017. http://umaclib3.umac.mo/record=b3691807.
Повний текст джерелаNgcamu, Nokubonga Slindele (Sma). "Awkward working postures and precision performance as an example of the relationship between ergonomics and production quality." Thesis, Rhodes University, 2009. http://eprints.ru.ac.za/1561/.
Повний текст джерелаNie, Yali. "Automatic Melanoma Diagnosis in Dermoscopic Imaging Base on Deep Learning System." Licentiate thesis, Mittuniversitetet, Institutionen för elektronikkonstruktion, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-41751.
Повний текст джерелаLarsman, Pernilla. "On the relation between psychosocial work environment and musculoskeletal symptoms : a structural equation modeling approach /." Stockholm : Arbetslivsinstitutet, förlagstjänst, 2006. http://ebib.arbetslivsinstitutet.se/ah/2006/ah2006_02.pdf.
Повний текст джерелаHashmi, Sumaiya F. "A Machine Learning Approach to Diagnosis of Parkinson’s Disease." Scholarship @ Claremont, 2013. http://scholarship.claremont.edu/cmc_theses/798.
Повний текст джерелаBell, Alison. "An ergonomic analysis of vacuum cleaning tasks using observational risk assessment tools." School of Health Sciences - Faculty of Health & Behavioural Sciences, 2008. http://ro.uow.edu.au/theses/126.
Повний текст джерелаCastaneda-Avila, Maira A. "The Role of a Monoclonal Gammopathy of Undetermined Significance Diagnosis in Healthcare Utilization." eScholarship@UMMS, 2021. https://escholarship.umassmed.edu/gsbs_diss/1135.
Повний текст джерелаSitt, Wing-hung Edward, and 薛穎雄. "Is the validity of non-invasive computerized tomography coronary angiography equivalent to invasive coronary angiography for theevaluation of coronary artery disease." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39724578.
Повний текст джерелаGenes, Nicholas G. "Chondrocyte Adhesion to RGD-bonded Alginate: Effect on Mechanotransduction and Matrix Metabolism: a Dissertation." eScholarship@UMMS, 2003. https://escholarship.umassmed.edu/gsbs_diss/89.
Повний текст джерелаMatzelle, Melissa M. "Inflammation Inhibits Osteoblast-Mediated Bone Formation in Rheumatoid Arthritis and Regulates the Wnt and BMP Signaling Pathways: A Dissertation." eScholarship@UMMS, 2012. https://escholarship.umassmed.edu/gsbs_diss/596.
Повний текст джерелаAl, Talalwah Waseem. "The vascular variability of the iliac system and clinical diagnosis in radiology and neurology." Thesis, University of Dundee, 2013. https://discovery.dundee.ac.uk/en/studentTheses/1aa955a0-1289-4670-b226-0eea5425ae0b.
Повний текст джерелаCrighton, Keith S. "Designing, producing and evaluating a multimedia computer based education system for teaching red eye diagnosis." Thesis, Queensland University of Technology, 1998. https://eprints.qut.edu.au/36744/1/36744_Digitised%20Thesis.pdf.
Повний текст джерелаSkelton, Sarah Anne. "Combined and additive effects of assembly tasks and constrained body postures." Thesis, Rhodes University, 2007. http://hdl.handle.net/10962/d1005185.
Повний текст джерелаAcharyya, Swarnali. "Elucidating molecular mechanisms of muscle wasting in chronic diseases." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1180096565.
Повний текст джерелаHott, Morgan E. "Cartilage tissue engineering: uses of injection molding and computer aided design for the fabrication of complex geometries with high dimensional tolerances: a dissertation." eScholarship@UMMS, 2007. https://escholarship.umassmed.edu/gsbs_diss/325.
Повний текст джерелаNi, Chih-Wen. "Discovery of mechanosensitive microrna and messenger RNA in mouse arterial endothelium and in cultured endothelial cells." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/34674.
Повний текст джерелаRoos, Annerine. "Validation of a rating scale for bedside cognitive assessment." Thesis, Stellenbosch : Stellenbosch University, 2004. http://hdl.handle.net/10019.1/50219.
Повний текст джерелаENGLISH ABSTRACT: Numerous tests exist for the assessment of general cognitive functioning. Most of these tests were developed within the discipline of psychology. Neuropsychological tests are very useful, but have some limitations. Administration of the tests is limited to a psychologist, is very timeconsuming in that it can take 3-8 hours to administer and often need specialized equipment. At the other end of the continuum are very brief screening tests. General practitioners, psychiatrists and occupational therapists, in addition to psychologists, also use these tests. Although useful, the short tests only provide limited information. An intermediate level test streamlining the assessment process between the very short and longer neuropsychological tests is therefore introduced by this study. The Bedside Cognitive Assessment Battery (BCAB) was developed in 1995 and are since used, at Tygerberg Hospital's Memory Clinic, to assess patients and teach students. The test comprehensively assesses the six main classes of cognitive functioning, namely attention and concentration, speech, memory, motor functioning, perceptual functioning and executive functioning. Approximately 35-45 minutes is required for administration and training is needed to administer the BCAB. No specialized equipment is needed for administration. The battery can therefore be used at the bedside, in the office or at old age homes. The aims of this study were to validate the BCAB for use with people aged eighteen years and older, and provide normative values for use in clinical settings. The test was revised in 1997 and 2001, and extensively so in 2002, but was never formally evaluated for validity. Well-known single tests were used to compile the BCAB. Most of these tests have proven validity and reliability, but only for foreign populations. In addition, some items were reformulated and others created by the researchers. The introduction of normative values would also be useful to assist in the delineation of cognitively intact and impaired individuals. This study succeeded in providing a table of normative values. One-hundred-and-sixty Afrikaans and English participants, and fourteen Xhosa participants were assessed in their mother tongue language. This project thus also introduced a Xhosa version of the BCAB. The purpose of the Xhosa version was to address the lack of culturally relevant cognitive assessment instruments. Results were evaluated for the effects of the variables' language, gender, age and education. The effect of language was most noticeable in the Xhosa group. Gender did not affect results as dramatically as age and especially, education. These significant effects on the aforementioned variables have been described in previous reports. The BCAB is thus relevant and useful as a detector of mild to moderate impairment. It can also be used to identify specific impairment. This can narrow down the investigation of psychologists, thus saving time and money. In addition, medical and nonmedical staff can use the BCAB. Some limitations were also identified. The sample used may limit the generalization of results. Some test items also need revision, along with further validation studies. Clinicians are therefore advised to use the BCAB only in addition to complete clinical examinations when making decisions regarding a patient's cognitive status. The BCAB appears to be a valid tool for bedside assessment. However, this study could only set the stage for further research, especially studies concerned with establishing normative values.
AFRIKAANSE OPSOMMING: Verskeie toetse bestaan vir die evaluering van algemene kognitiewe funksionering, waarvan die meeste ontwikkel is binne die sielkunde. Neuro-sielkundige toetse is baie bruikbaar, maar het sekere beperkings. Administrasie van die toetse is beperk tot sielkundiges, maar tydrowend weens 'n tydsduur van drie tot agt uur, en verg dikwels gespesialiseerde toerusting. Aan die ander kant is heelwat kart siftings-toetse beskikbaar. Aigemene praktisyns, sielkundiges en arbeidsterapeute, asook sielkundiges, gebruik dit. Hoewel bruikbaar, bied die kart toetse beperkte inligting. 'n lntermediere vlak toets om die evaluerings-proses tussen kart en langer neuro-sielkundige toetse te integreer word met hierdie studie beoog. Die Bedkant Kognitiewe Evaluasie Battery (BKEB) is in 1995 ontwikkel en gebruik in die Geheue-kliniek van die Tygerberg Hospitaal om pasiente te evalueer en studente op te lei. Die toets is gerig op die omvattende evaluering van die ses hoof-klasse van kognitiewe funksionering. Hierdie klasse omvat aandag en konsentrasie, spraak, geheue, motoriese funksionering, perseptuele funksionering en uitvoerende funksionering. Sowat 35 tot 45 minute word benodig vir administrasie terwyl opleiding vereis word vir die neem van die toets. Geen gespesialiseerde toerusting is nodig nie. Die battery kan dus by die bedkant, in die kantoor of in ouetehuise gebruik word. Die doelwitte van hierdie studie is om die BKEB te evalueer in gebruik by 18-jariges en ouer, en normatiewe waardes te bepaal vir gebruik in kliniese omgewings. Die toets is in 1997 en 2001 hersien. In 2002 is dit uitvoerig hersien, maar nooit ge-evalueer vir geldigheid nie. Bekende enkel-toetse is gebruik am die BKEB saam te stel. Dit is as geldig en betroubaar bewys, hoewel slegs onder buitelandse bevolkingsgroepe. Hierbenewens is sekere items herformuleer en ander bygewerk deur die navorsers. Normatiewe waardes sal oak handig wees in die afbakening van kognitief normaal-funksionerende en kognitief-ingekorte individue. Hierdie studie het daarin geslaag am 'n tabel van normatiewe waardes daar te stel. Een-honderd-en-sestig Afrikaans- en Engels-sprekendes, en 14 Xhosa-sprekendes is tydens hierdie studie in hulle moedertaal ge-evalueer. Hierdie projek het dus oak 'n Xhosaweergawe van die BKEB geskep. Die doel van die Xhosa-weergawe was am die gebrek aan 'n kultureel toepaslike kognitiewe instrument te beklemtoon. Resultate is ge-evalueer gedagtig aan veranderlikes soos taal, geslag, ouderdom en opleidingsvlak. Taal het die grootste invloed gehad op uitslae van Xhosa-deelnemers. Geslag het nie die uitslae so dramaties bernvloed soos ouderdom, en veral opleidingsvlak nie. Literatuur het meestal die groot uitwerking van hierdie veranderlikes bevestig. Die BKEB is dus relevant en handig in die naspeuring van ligte tot matige kognitiewe ingekortheid. Dit kan ook gebruik word om spesifieke kognitiewe ingekortheid te identifiseer. Die kan die omvang van ondersoek deur sielkundiges vernou, wat kan lei tot In groot besparing in tyd en geld. Hierbenewens kan mediese en nie-mediese personeel aangewend word in die gebruik van die BKEB. Sekere tekortkominge is ge·,dentifiseer. Die steekproef mag egter die veralgemening van die uitslae beperk. Sekere toets-items mag ook hersiening vereis, tesame met verdere geldigheid-studies. Kliniese praktisyns word daarom aangeraai om die BKEB slegs in aanvulling tot omvattende kliniese ondersoeke te gebruik vir besluite m.b.t. In pasient se kognitiewe status. Die BKEB kom voor as In geldige instrument vir bedkant evaluering. Hierdie studie kon egter slegs die tafel dek vir verdere ondersoek, veral t.o.v. studies wat poog om normatiewe waardes daar te stel.
Roach, Denise Margaret. "Upregulation of matrix metalloproteinases -2 and -9 and type IV collagen degradation in skeletal muscle reperfusion injury." Title page, contents and abstract only, 2002. http://web4.library.adelaide.edu.au/theses/09MD/09mdr6281.pdf.
Повний текст джерелаThomas, Saralene Iona. "Genetic markers in the differential diagnosis in a family setting of episodic loss of consciousness." Thesis, Stellenbosch : Stellenbosch University, 2000. http://hdl.handle.net/10019.1/51777.
Повний текст джерелаBigordà, Sagué Albert. "Diseño y validación de una aplicación informática de sospecha de patología del aparato locomotor en el hombro." Doctoral thesis, Universitat de Lleida, 2017. http://hdl.handle.net/10803/405802.
Повний текст джерелаSe expone una demora significativa para acceder a tratamiento de fisioterapia en los aquejados por dolor de hombro. Se propone mejorarla con el diseño y validación de una aplicación informática autoadministrada para la sospecha de patología. Se reclutaron usuarios con dolor de más de 6 semanas de evolución en servicios de rehabilitación y traumatología. Se ha realizado una revisión bibliográfica, una prueba de factibilidad, una revisión por evaluadores expertos según la metodología Delphi, una prueba piloto con análisis de la fiabilidad y una prueba de validación en 250 pacientes. Los valores de validez fueron: CP+ 7,8 y CP- 0,1 para la radiculopatía, CP+ 4,1 y CP- 0,4 para la artrosis glenohumeral, CP+ 15,5 y CP- 0,2 para la inestabilidad, CP+ 17,2 y CP- 0,2 para la rotura masiva del manguito rotador, CP+ 6,2 y CP- 0,2 para la retracción capsular, CP+ 4,0 y CP- 0,3 para el síndrome subacromial, y CP+ 2,5 y CP- 0,6 para la artropatía acromioclavicular. Se ha obtenido un coeficiente Kappa del 0,67 y una media de correcta clasificación del 84% para un mismo paciente. Los factores que influyeron negativamente en la precisión fueron la rotura masiva del manguito rotador, la artropatía acromioclavicular, una edad superior a 55 años y una intensidad del dolor (EVA) superior a 8 (p>0,05). Se expone una buena fiabilidad y una aceptable validez para algunas patologías, pero una insuficiente capacidad para la sospecha de la totalidad del cuadro clínico en un mismo paciente.
There is a significant delay in accessing physiotherapy treatment for those patients with shoulder pain. It is proposed to improve it with the design and validation of a self-administered computer application for suspected pathology. Patients with pain for more than six weeks in rehabilitation and traumatology services were recruited. A bibliographic review, a feasibility test, a review by expert evaluators according to the Delphi methodology, a pilot test with reliability analysis and a validation test in 250 patients were carried out. Validity values were: LR+ 7,8 and LR- 0,1 for radiculopathy; LR+ 4,1 and LR- 0,4 for glenohumeral osteoarthritis; LR+ 15,5 and LR- 0,2 for instability; LR+ 17,2 and LR- 0,2 for massive rotator cuff tear; LR+ 6,2 and LR- 0,2 for capsular retraction; LR+ 4,0 and LR- 0,3 for subacromial syndrome; and LR+ 2,5 and LR- 0,6 for acromioclavicular arthropathy. A kappa coefficient of 0,67 and an average of correct classification for the same patient of 84% were obtained. Factors that negatively influenced precision were massive rupture of the rotator cuff, acromioclavicular arthropathy, age over 55 years and pain intensity (VAS) over 8 (p> 0,05). The result were good reliability and acceptable validity, but insufficient capacity to suspect whole clinical state in the same patient.
Rauch, Hanz Frederick. "The development of a system that emulates percussion to detect the borders of the liver." Thesis, Stellenbosch : University of Stellenbosch, 2009. http://hdl.handle.net/10019.1/2331.
Повний текст джерелаPercussion is a centuries old bedside diagnostic technique that is used to diagnose various conditions of the thorax and abdomen, among these, abnormalities of the liver. The physician taps the patient’s skin in the area of interest to determine the qualities or presence of the underlying tissue or organ, by listening to the generated sound. The research contained in this thesis views percussion as a system identification method which uses an impulse response to identify the underlying system. A design employing an electromagnetic actuator as input pulse generator and accelerometer as impulse response recorder was motivated and built. Tests were performed on volunteers and the recorded signals were analysed to find methods of identifying the presence of the liver from these signals. The analyses matched signals to models or simply extracted signal features and matched these model parameters or signal features to the presence of the liver. Matching was done using statistical pattern recognition methods and the true presence of the liver was established using MR images. Features extracted from test data could not be matched to the presence of the liver with sufficient confidence which led to the conclusion that either the test, apparatus or analysis was flawed. The lack of success compelled a further test on a mock-up of the problem – a silicone model with an anomaly representing the organ under test. Results from these tests showed that signals should be measured further from the actuator and the approach followed during this test could lead to the successful location of the anomaly and discrimination between subtle differences in the consistency thereof. It is concluded that further research should aim to first validate percussion as performed by the physician and increase complexity in a phased manner, validating results and apparatus at each step. The approach followed was perhaps too bold in light of the lack of fundamental understanding of percussion and the underlying mechanisms.
Hashmi, Sumaiya F. "A DNA Computer for Glioblastoma Multiforme Diagnosis and Drug Delivery." Scholarship @ Claremont, 2013. http://scholarship.claremont.edu/cmc_theses/799.
Повний текст джерелаVan, der Merwe Ruben Gerhard. "The development of a novel fluorescentmarker phage technology system for the early diagnosis of tuberculosis disease." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71908.
Повний текст джерелаIncludes bibliography
ENGLISH ABSTRACT: Mycobacterium tuberculosis, the causative organism of tuberculosis (TB), is a major cause for mortality and morbidity world-wide with a death toll only second to HIV among infectious diseases. Drug resistance is widespread and cases of multiple drug resistant TB (MDR-TB) and extensively drug resistant TB (XDR-TB) have emerged in several countries. Drug treatment is problematic and new drugs are not developed rapidly enough to offset the rapid drug resistance mutation rate of M. tuberculosis. Simple and effective diagnostics are required to contain the spread of the disease as current routine diagnostics are not fulfilling this role. Additionally, current rapid TB diagnostics are out of reach to resource poor settings due to infrastructure, cost and skill requirements. Novel TB diagnostics are thus required that meet these requirements. Mycobacteriophages are phages that infect mycobacteria and could offer a viable and cost effective alternative rapid TB diagnostics. In this study, an affinity-tagged fluorescent reporter mycobacteriophage is described, which was engineered to act as a TB diagnostic. Its performance proved favourable and superior to current existing mycobacteriophage-based TB diagnostics.
AFRIKAANSE OPSOMMING: Mycobacterium tuberculosis, die organisme verantwoordelik vir tuberkulose (TB), is `n groot bron van mortaliteit en morbiditeit wêreldwyd en slegs HIV is verantwoordelik vir groter getalle sterftes as gevolg van n aansteeklike siekte. Middelweerstandigheid is algemeen en gevalle van meervoudigemiddelweerstandige tuberkulose (MDR-TB) en uiters weerstandige tuberkulose (XDR-TB) kom in verskeie lande voor. Antibiotika behandeling is problematies en nuwe anti-TB middels word nie vinnig genoeg ontwikkel om die antibiotika weerstandigheid mutasie spoed van M. tuberculosis te bekamp nie. Doeltreffende diagnostiese toetse word benodig om die verspreiding van die siekte te beheer en bestaande roetine diagnostiese toetse voldoen tans nie aan hierdie vereiste nie. Behalwe hiervoor, is huidige vinnige TB diagnostiese toetse buite bereik van arm instansies weens vereistes aan infrastruktuur, meegaande kostes en werknemervaardigheid. Nuwe TB diagnostiese toetse is dus nodig om aan hierdie vereistes te voldoen. Mikobacteriofaage is fage wat mikobacteria infekteer en kan moontlik 'n lewensvatbare en koste-effektiewe alternatief bied vir vinnige TB diagnostiese toetse. In hierdie studie word 'n affiniteitgekoppelde fluoreserende rapporteringsmikobakteriofaag beskryf wat ontwerp is om op te tree as `n nuwe vinnige TB diagnostiese toets. Die werking hiervan vertoon gunstige en beter resultate as die huidige, mikobacteriofaaggebaseerde TB-diagnostiese toetse.
Wang, Yee-moon Angela, and 王依滿. "Utility of cardiac biomarkers in end-stage renal disease patients on maintenance peritoneal dialysis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41508968.
Повний текст джерелаHaga, Kristin Kerr. "The combined application of 'H MRI and '19F MRS to the study of cerebroprotection." Thesis, University of London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312006.
Повний текст джерелаOladele, Oluwafemi. "Characterization of feline borna disease virus /." Uppsala : Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, 2006. http://epsilon.slu.se/10454915.pdf.
Повний текст джерелаGaldun, John P. "A MECHANISTIC STUDY OF AN iPSC MODEL FOR LEIGH’S DISEASE CAUSED BY MtDNA MUTATAION (8993 T>G)." VCU Scholars Compass, 2016. http://scholarscompass.vcu.edu/etd/4411.
Повний текст джерела