Готові списки джерел за темами / Multi-stimuli response

Добірка наукової літератури з теми "Multi-stimuli response"

Автор: Grafiati

Опубліковано: 7 липня 2024

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Статті в журналах з теми "Multi-stimuli response":

Tholen, Haley, and Ryan L. Harne. "Multi-material stimuli-responsive hydrogels with optically induced actuation." Journal of the Acoustical Society of America 151, no. 4 (April 2022): A179. http://dx.doi.org/10.1121/10.0011023.

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A vision for soft, autonomous materials entails synthesis of multiple senses in multifunctional materials where material response requires sensitivity to external stimuli. Stimuli-responsive hydrogels are of particular interest for optically induced mechanical response due to the ability to transform external stimuli into large, reversible shape change. Specifically, temperature-responsive hydrogels are broadly used and can be designed to achieve deformation through the photothermal effect as a result of surface plasmonic resonance of gold nanoparticles. Here, a multi-material stimuli-responsive hydrogel network with embedded gold nanoparticles is demonstrated in a unit cell pattern with anisotropic swelling behavior in response to visible light. Reversible, anisotropic swelling leads to bending motion that contributes to the development of soft, autonomous materials.

Mei, Xiaofei, Jingwei Wang, Zhonggao Zhou, Shiyi Wu, Limei Huang, Zhenghuan Lin, and Qidan Ling. "Diarylmaleic anhydrides: unusual organic luminescence, multi-stimuli response and photochromism." Journal of Materials Chemistry C 5, no. 8 (2017): 2135–41. http://dx.doi.org/10.1039/c6tc05519b.

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Novel maleic anhydrides symmetrically substituted by two aromatic rings exhibit distinct emission behaviours: aggregation-caused quenching (ACQ), aggregation-induced emission (AIE), and dual-state emission (DSE) in both solution and the solid state. Appropriate modifications were made to turn ACQ/AIE into DSE and realize full-color DSE.

Sathiyaraj, Munusamy, Kumaravelu Pavithra, and Viruthachalam Thiagarajan. "Azine based AIEgens with multi-stimuli response towards picric acid." New Journal of Chemistry 44, no. 20 (2020): 8402–11. http://dx.doi.org/10.1039/d0nj01324b.

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Son, Hyegyo, and ChangKyu Yoon. "Advances in Stimuli-Responsive Soft Robots with Integrated Hybrid Materials." Actuators 9, no. 4 (November 14, 2020): 115. http://dx.doi.org/10.3390/act9040115.

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Hybrid stimuli-responsive soft robots have been extensively developed by incorporating multi-functional materials, such as carbon-based nanoparticles, nanowires, low-dimensional materials, and liquid crystals. In addition to the general functions of conventional soft robots, hybrid stimuli-responsive soft robots have displayed significantly advanced multi-mechanical, electrical, or/and optical properties accompanied with smart shape transformation in response to external stimuli, such as heat, light, and even biomaterials. This review surveys the current enhanced scientific methods to synthesize the integration of multi-functional materials within stimuli-responsive soft robots. Furthermore, this review focuses on the applications of hybrid stimuli-responsive soft robots in the forms of actuators and sensors that display multi-responsive and highly sensitive properties. Finally, it highlights the current challenges of stimuli-responsive soft robots and suggests perspectives on future directions for achieving intelligent hybrid stimuli-responsive soft robots applicable in real environments.

Khattab, Tawfik A., Brylee David B. Tiu, Sonya Adas, Scott D. Bunge, and Rigoberto C. Advincula. "Solvatochromic, thermochromic and pH-sensory DCDHF-hydrazone molecular switch: response to alkaline analytes." RSC Advances 6, no. 104 (2016): 102296–305. http://dx.doi.org/10.1039/c6ra24113a.

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Tiselko, Vasilii S., Maxim Volgushev, Dirk Jancke, and Anton V. Chizhov. "Response retention and apparent motion effect in visual cortex models." PLOS ONE 18, no. 11 (November 2, 2023): e0293725. http://dx.doi.org/10.1371/journal.pone.0293725.

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Apparent motion is a visual illusion in which stationary stimuli, flashing in distinct spatial locations at certain time intervals, are perceived as one stimulus moving between these locations. In the primary visual cortex, apparent-motion stimuli produce smooth spatio-temporal patterns of activity similar to those produced by continuously moving stimuli. An important prerequisite for producing such activity patterns is prolongation of responses to brief stimuli. Indeed, a brief stimulus can evoke in the visual cortex a long response, outlasting the stimulus by hundreds of milliseconds. Here we use firing-rate based models with simple ring structure, and biologically-detailed conductance-based refractory density (CBRD) model with retinotopic space representation to analyze the response retention and the origin of smooth profiles of activity in response to apparent-motion stimuli. We show that the strength of recurrent connectivity is the major factor that endorses neuronal networks with the ability for response retention. The same strengths of recurrent connections mediate the appearance of bump attractor in the ring models. Factors such as synaptic depression, NMDA receptor mediated currents, and conductances regulating spike adaptation influence response retention, but cannot substitute for the weakness of recurrent connections to reproduce response retention in models with weak connectivity. However, the weakness of lateral recurrent connections can be compensated by layering: in multi-layer models even with weaker connections the activity retains due to its feedforward propagation from layer to layer. Using CBRD model with retinotopic space representation we further show that smooth spatio-temporal profiles of activity in response to apparent-motion stimuli are produced in the models expressing response retention, but not in the models that fail to produce response retention. Together, these results demonstrate a link between response retention and the ability of neuronal networks to generate spatio-temporal patterns of activity, which are compatible with perception of apparent motion.

Borirakarawin, Manorot, and Yunyong Punsawad. "Event-Related Potential-Based Brain–Computer Interface Using the Thai Vowels’ and Numerals’ Auditory Stimulus Pattern." Sensors 22, no. 15 (August 5, 2022): 5864. http://dx.doi.org/10.3390/s22155864.

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Herein, we developed an auditory stimulus pattern for an event-related potential (ERP)-based brain–computer interface (BCI) system to improve control and communication in quadriplegia with visual impairment. Auditory stimulus paradigms for multicommand electroencephalogram (EEG)-based BCIs and audio stimulus patterns were examined. With the proposed auditory stimulation, using the selected Thai vowel, similar to the English vowel, and Thai numeral sounds, as simple target recognition, we explored the ERPs’ response and classification efficiency from the suggested EEG channels. We also investigated the use of single and multi-loudspeakers for auditory stimuli. Four commands were created using the proposed paradigm. The experimental paradigm was designed to observe ERP responses and verify the proposed auditory stimulus pattern. The conventional classification method produced four commands using the proposed auditory stimulus pattern. The results established that the proposed auditory stimulation with 20 to 30 trials of stream stimuli could produce a prominent ERP response from Pz channels. The vowel stimuli could achieve higher accuracy than the proposed numeral stimuli for two auditory stimuli intervals (100 and 250 ms). Additionally, multi-loudspeaker patterns through vowel and numeral sound stimulation provided an accuracy greater than 85% of the average accuracy. Thus, the proposed auditory stimulation patterns can be implemented as a real-time BCI system to aid in the daily activities of quadratic patients with visual and tactile impairments. In future, practical use of the auditory ERP-based BCI system will be demonstrated and verified in an actual scenario.

Hu, Cheng, Weihua Zhuang, Tao Yu, Liang Chen, Zhen Liang, Gaocan Li, and Yunbing Wang. "Multi-stimuli responsive polymeric prodrug micelles for combined chemotherapy and photodynamic therapy." Journal of Materials Chemistry B 8, no. 24 (2020): 5267–79. http://dx.doi.org/10.1039/d0tb00539h.

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López, Jesús, María Murillo, Ginés Lifante-Pedrola, Eugenio Cantelar, Javier Gonzalez-Platas, Ulises R. Rodríguez-Mendoza, and Pilar Amo-Ochoa. "Multi-stimulus semiconductor Cu(i)–I-pyrimidine coordination polymer with thermo- and mechanochromic sensing." CrystEngComm 24, no. 2 (2022): 341–49. http://dx.doi.org/10.1039/d1ce01315g.

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The 1D-[Cu(aClpym)I]n coordination polymer behaves as an intelligent material with response to different stimuli since its emission is altered with temperature and with varying modes of pressure, making it a potential multi-response material.

Saravanakumar, Kandasamy, Xiaowen Hu, Davoodbasha M. Ali, and Myeong-Hyeon Wang. "Emerging Strategies in Stimuli-Responsive Nanocarriers as the Drug Delivery System for Enhanced Cancer Therapy." Current Pharmaceutical Design 25, no. 24 (October 3, 2019): 2609–25. http://dx.doi.org/10.2174/1381612825666190709221141.

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The conventional Drug Delivery System (DDS) has limitations such as leakage of the drug, toxicity to normal cells and loss of drug efficiency, while the stimuli-responsive DDS is non-toxic to cells, avoiding the leakage and degradation of the drug because of its targeted drug delivery to the pathological site. Thus nanomaterial chemistry enables - the development of smart stimuli-responsive DDS over the conventional DDS. Stimuliresponsive DDS ensures spatial or temporal, on-demand drug delivery to the targeted cancer cells. The DDS is engineered by using the organic (synthetic polymers, liposomes, peptides, aptamer, micelles, dendrimers) and inorganic (zinc oxide, gold, magnetic, quantum dots, metal oxides) materials. Principally, these nanocarriers release the drug at the targeted cells in response to external and internal stimuli such as temperature, light, ultrasound and magnetic field, pH value, redox potential (glutathione), and enzyme. The multi-stimuli responsive DDS is more promising than the single stimuli-responsive DDS in cancer therapy, and it extensively increases drug release and accumulation in the targeted cancer cells, resulting in better tumor cell ablation. In this regard, a handful of multi-stimuli responsive DDS is in clinical trials for further approval. A comprehensive review is crucial for addressing the existing knowledge about multi-stimuli responsive DDS, and hence, we summarized the emerging strategies in tailored ligand functionalized stimuli-responsive nanocarriers as the DDS for cancer therapies.

Більше джерел

Дисертації з теми "Multi-stimuli response":

Peng, Tao. "Permeability of responsive polymer-grafted porous membranes, temperature, pH and multi-stimuli response." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0020/NQ49832.pdf.

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Katsumi, Shiho. "Multi-Stimuli Responsive β-Diketonate Derivatives, from Molecules to Self-Assemblies". Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASF004.

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Les molécules fluorescentes multiréactives peuvent ajuster leurs propriétés de fluorescence en réponse à des stimuli externes tels que des changements de température, de pression et d'environnement chimique. Cette capacité d'adaptation pourrait orienter efficacement le développement des technologies de capteurs, d'affichage et d'imagerie, offrant ainsi de nombreuses applications. Le mécanofluorochromisme (MFC) est une propriété fascinante des systèmes multiréactifs, où les matériaux subissent des changements fluorescents sous l'effet de contraintes mécaniques telles que la compression, le cisaillement et la friction. Les complexes difluorure de bore à ligand dicétone (DFB) attirent l'attention pour leurs caractéristiques photophysiques uniques, présentant non seulement un MFC mais aussi un polymorphisme et une fluorescence intense à l'état solide et en solution. Ce travail vise à explorer des méthodologies innovantes pour concevoir et synthétiser des matériaux DFB multi-réactifs et leurs composés précurseurs. L'accent est mis sur l'étude des caractéristiques photophysiques de ces matériaux et de leur réactivité à divers stimuli. En outre, les mécanismes sous-jacents du MFC sont étudiés. Tout d'abord, un nouveau DFB multiréactif et multicolore est discuté. La synthèse de l'amino-méthoxy-DFB (DFB-NH₂), impliquant l'introduction d'une amine primaire dans le cycle phényle par réarrangement de Curtius, a été entreprise. Grâce au groupe NH₂, la molécule présente un transfert de charge intramoléculaire (ICT) en solution et à l'état cristallin. Une structure de type quinoïde et une structure typique de dimère de type H tête-queue sont observées à l'état cristallin. Le cristal à faible émission rouge foncé présente une émission décalée vers le bleu après un frottement mécanique, ce qui constitue un comportement MFC original. Le composé déposé sur une feuille de papier présente également un MFC significatif. En outre, une réactivité acide/base caractéristique est observée en solution, dans les films polymères dopés et les échantillons de poudre. Deuxièmement, le système multiréactif est inséré dans une molécule symétrique en C₃. Un nouveau composé β-dicétone C₃-symétrique, BTA-D3, et son homologue monomère, D, ont été synthétisés avec succès. Notamment, l'émission induite par l'agrégation (AIE) est observée dans BTA-D3 contrairement à D. En outre, BTA-D3 présente des caractéristiques de fluorescence dépendantes du polymorphe, formant des fibres 1D avec une émission jaune dans le système THF/eau, tout en formant des feuilles 2D avec une émission bleue. En outre, les propriétés de transfert d'énergie intramoléculaire sont démontrées par BTA-D3, ce qui le distingue de D. Troisièmement, la migration d'énergie dans le gel, la formation d'assemblages, les effets mécaniques et la complexation du bore du BTA-D3 ont été explorés. Ces expériences ont permis de caractériser les propriétés de gélification et la fluorescence, révélant leur dépendance à la morphologie moléculaire. L'analyse de l'anisotropie dans le gel donne un aperçu de la migration de l'énergie à l'intérieur des molécules et entre elles, mettant en évidence des structures cruciales pour un auto-assemblage efficace. La structure unique contribue à diverses propriétés stimuli-réceptives, telles que l'induction chirale par des solvants chiraux et le MFC. Notamment, la boration de BTA-D3 donne une molécule très luminescente avec un déplacement marqué de la fluorescente vers le bleu par MFC. Ces résultats contribuent à une meilleure compréhension des molécules avec une symétrie C₃ et donnent un aperçu des stratégies de contrôle de l'assemblage moléculaire afin d'obtenir diverses colorations de fluorescence dans les matériaux moléculaires. L'ensemble de la thèse vise à fournir des lignes directrices pratiques et des idées pour le développement de nouveaux matériaux luminescents, contribuant ainsi à des avancées dans le domaine avec des applications potentielles
Multi-responsive fluorescent molecules can adjust their fluorescence properties in response to external stimuli such as changes in temperature, pressure, and chemical environment. This adaptability could efficiently direct the development of sensors, displays, and imaging technologies, providing various applications in the future. Mechanofluorochromism (MFC) is a fascinating property in multi-responsive systems, where materials undergo fluorescent changes under mechanical stress like compression, shear force, and friction. Difluoroboron β-diketonate (DFB) compounds draw attention for unique photophysical traits, featuring not only MFC but also polymorphism and intense fluorescence in both solid and solution. This research aims to explore innovative methodologies for designing and synthesizing multi-responsive DFB materials and their precursor compounds. Emphasis is placed on investigating these materials' photophysical characteristics and responsiveness to diverse stimuli. Additionally, the underlying mechanisms of MFC are studied. To achieve these objectives, a comprehensive approach is employed, integrating fluorescence spectroscopy, various microscopic techniques, anisotropic experiments, theoretical calculations, and other relevant methodologies.In the first topic of this thesis, a novel multi-responsive and multicolor DFB is discussed. The synthesis of amino-methoxy-DFB (DFB-NH₂), involving the introduction of a primary amine into the phenyl ring through Curtius rearrangement, was undertaken. Thanks to the NH₂ group, the molecule exhibits intramolecular charge transfer (ICT) in solution and in the crystalline phase. A quinoid-like structure and a typical head-to-tail H-type dimer structure are observed in the crystal state. The single crystal with dark-red weak emission demonstrates a blue-shifted emission after mechanical smearing, which constitutes an original MFC behavior. The drop-casted sample on a paper sheet also demonstrates significant MFC. Additionally, characteristic acid-/base-responsivity is observed in the solution phase, polymer-dispersed films, and powder samples.In the second topic of this thesis, the multi-responsive system is delved into a C₃-symmetrical molecule. A novel C₃-symmetrical β-diketone compound, BTA-D3, and its monomeric counterpart, D, are successfully synthesized. Notably, Aggregation-induced emission (AIE) is observed in BTA-D3 contrary to D. Additionally, BTA-D3 displays polymorph-dependent fluorescence characteristics, forming 1D fibers with yellow emission in the THF/water system, while forming 2D sheets with blue emission. In addition, intramolecular energy transfer properties are demonstrated by BTA-D3, distinguishing it from D.In the third topic of this thesis, energy migration in gel, assembly formations, mechanical effects, and boron complexation of BTA-D3 were explored. Through these experiments, the gelation properties and fluorescence are characterized, revealing their dependence on molecular morphology. Anisotropy analysis in gel offers insights into energy migration within and between molecules, highlighting crucial structures for efficient self-assembly. The unique structure contributes to diverse stimuli-responsive properties, such as chiral induction by chiral solvents and MFC. Notably, boronation of BTA-D3 results in a highly luminescent molecule with a distinctive blue-shift in MFC. These findings contribute to an enriched comprehension of C₃-symmetrical molecules and offer insights into strategies for controlling molecular alignment to achieve diverse fluorescence coloration in molecular materials. The whole thesis seeks to provide practical guidelines and insights for developing new luminescent materials, contributing to advancements in the field with potential applications

Michal, Brian. "Multi-Functional Stimuli-Responsive Polymers." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1459440396.

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Kaufmann, Martin. "Lipid Bilayers Supported by Multi-Stimuli Responsive Polymers." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-106231.

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Artificial lipid bilayers formed on solid surface supports are widespread model systems to study physical, chemical, as well as biological aspects of cell membranes and fundamental interfacial interactions. The approach to use a thin polymer film representing a cushion for lipid bilayers prevents incorporated membrane proteins from pinning to the support and mimics the native environment of a lipid bilayer in certain aspects of the extracellular matrix and intracellular structures. A key component for cell anchorage to extracellular fibronectin is the transmembrane adhesion receptor alpha(5)beta(1) integrin. Its transport dynamics and clustering behavior plays a major role in the assembly of focal adhesions, which mediate mechanical forces and biochemical signals of cells with their surrounding. The system investigated herein is envisioned to use extrinsically controlled stimuli-responsive polymer cushions to tune the frictional drag between polymer cushion and mobile membranes with incorporated integrins to actively regulate lipid membrane characteristics. To attain this goal, a temperature- and pH-responsive polymer based on poly(N-isopropylacrylamide) copolymers containing varying amounts of carboxyl-group-terminated comonomers at different aliphatic spacer lengths (PNIPAAm-co-carboxyAAM) was surface-grafted to a poly(glycidyl methacrylate) anchorage layer. The swelling transitions were characterized using atomic force microscopy, ellipsometry and quartz crystal microbalance with dissipation monitoring (QCM-D) and found to be tunable over a wide range of temperature and pH. In agreement with the behavior of the polymers in solution, longer alkyl spacers decreased the phase transition temperature T(P) and higher contents of carboxylic acid terminated comonomers increased T(P) at alkaline conditions and decreased T(P) at acidic conditions. Remarkably, the point where the degree of carboxyl group deprotonation balances the T(P)-lowering effect of the alkyl spacer was distinctive for each alkyl spacer length. These findings illustrate how the local and global balance of hydrophilic and hydrophobic interactions along the copolymer chain allows to adjust the swelling transition to temperatures below, comparable, or above those observed for PNIPAAm homopolymers. Additionally, it could be shown that surface-grafting leads to a decrease in T(P) for PNIPAAm homopolymers (7°C) and copolymers (5°C - 10°C). The main reason is the increase in local polymer concentration of the swollen film constrained by dense surface anchorage in comparison to the behavior of dilute free chains in solution. In accordance with the Flory-Huggins theory, T(P) decreases with increasing concentration up to the critical concentration. Biological functionalization of the PNIPAAm-co-carboxyAAm thin films was demonstrated for the cell adhesion ligand peptide cRGD via carbodiimide chemistry to mimic extracellular binding sites for the cell adhesion receptors integrin. The outcome of QCM-D measurements of cRGD-functionalized surfaces showed a maintained stimuli-responsiveness with slight reduction in T(P). A drying/rehydration procedure of a 9:1 lipid mixture of the cationic lipid dioleoyl-trimethylammoniumpropane (DOTAP) and the zwitterionic dioleoyl-phosphatidylcholine (DOPC) was utilized to form lipid bilayer membranes on PNIPAAm-co-carboxyAAM cushions. Fluorescence recovery after photobleaching (FRAP) revealed that lipid mobility was distinctively higher (6.3 - 9.6) µm2 s-1 in comparison to solid glass support ((3.0 - 5.9) µm2 s-1). In contradiction to the initial expectations, modulation of temperature and pH led to poor variations in lipid mobility that did not correlate with the PNIPAAm cushion swelling state. The results suggested a weak coupling of the lipid bilayer with PNIPAAm polymer cushions that can be slightly tuned by electrostatic interactions. The transmembrane adhesion receptor alpha(5)beta(1) integrin was reconstituted into liposomes consisting of DOPC/sphingomyelin/cholesterol 2:2:1 for the formation of polymer cushioned bilayers. PNIPAAm- co-carboxyAAM and maleic acid (MA) copolymers were used as cushions, both with the option for cRGD functionalization. On the MA copolymer cushions, fusion of proteoliposomes resulted in supported bilayers with mobile lipids as confirmed by FRAP. However, incorporated integrins were immobile. In an attempt to explain this observation, the medium-sized cytoplasmic integrin domain was accounted to hamper the movement by steric interactions with the underlying polymer chains in conjunction with electrostatic interactions of the cationic cytoplasmic domain with the oppositely charged MA copolymer. On the PNIPAAm-co-carboxyAAM cushion only a drying/rehydration procedure lead to bilayer formation. However, again the integrins were immobile, presumably due to the harsh treatment during preparation. Nevertheless, the results of the investigated set of PNIPAAm copolymer films suggest their application as temperature- and pH-responsive switchable layers to control interfacial phenomena in bio-systems at different physiological conditions. The PNIPAAm-co-carboxyAAm cushioned bilayer system represents a promising step towards extrinsically controlled membrane – substrate interactions.

Gernhardt, Marvin. "Multi-material microstructures with novel stimuli-responsive properties." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/210195/1/Marvin_Gernhardt_Thesis.pdf.

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This thesis presents the development of two novel materials that undergo drastic changes when exposed to a certain trigger. One of them becomes harder and stiffer when exposed to visible light of a certain wavelength and one of them degrades when exposed to a certain enzyme. The properties of the materials were investigated thoroughly. The advanced 3D printing technique direct laser writing was used to fabricate microscopic structures from both materials. Such microstructures possessing highly adaptable properties could be used as scaffold materials for cells in order to study their development as a response to the triggered changes.

Cresswell, Philip Thomas. "Multi-component stimuli-responsive polymer brushes grafted from flat surfaces." Thesis, University of Bristol, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.633147.

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Grafting polymer brushes from surfaces is an effective method of surface modification. Importantly, such coatings are robust due to covalent bonding, establishing a chemically and mechanically stable interface not relying solely on weak physical bonding (e . g. van del' Waals forces) as alternative coating methods do. Polymer brushes have been shown to mediate effective lubrication, among other applications. In this work, stainless steel is the substrate of interest and a novel system of reagents specifically designed for this material has been applied to produce various polymer brush structures by surface initiated atom transfer radical polymerisation (SI-ATRP). For friction reduction in an aqueous environment, a multi-component hierarchical brush system, incorporating an underlying hydrophobic layer and a hydrophilic block on the outer periphery was proposed. The first layer of brushes, closest to the metals surface, was exploited as a barrier to drive water away from the solid interface, hence minimising corrosion of the metal, with the facile wetting of the second block giving a hydration layer at the interface to promote lubrication in the presence of water. Additionally, the hydrocarbon brush chosen as the outer layer in this system is known to be thermoresponsive, as chains collapse and become more hydrophobic at elevated temperatures. A co-polymer structure was employed and allowed the critical temperature of the brush to be tuned over a range of temperatures. This tuneable thermal response was intended to give switchable surface friction. Furthermore, use of an industrially relevant material in these investigations should potentially lead to a more straightforward utilisation in real world applications.

Cheng, Holden. "Auditory-nerve fiber responses to amplitude modulated tones and multi-tonal stimuli." Thesis, Massachusetts Institute of Technology, 2005. http://hdl.handle.net/1721.1/33844.

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Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2005.
Includes bibliographical references (leaves 35-36).
In normal-hearing ears, sound waves are amplified within the cochlea and a small fraction of the sound energy travels backward out into the ear canal, producing sounds known as "otoacoustic emissions" (OAE) that can be measured with a sensitive microphone. One class of OAE, called "stimulus-frequency-otoacoustic-emissions" (SFOAEs), has been hypothesized to be produced by a process known as "coherent reflection filtering" (CRF). The CRF theory provides a prediction between the SFOAE group delay and the group delays of tone responses on the basilar membrane within the cochlea. Using single and multiple-tone stimuli, we collected data from the firing patterns of single auditory-nerve-fibers (ANFs) from which basilar-membrane tone-response group delays can be calculated for both high and low best-frequency (BF) positions along the basilar membrane. These calculated basilar-membrane group delays were compared to published SFOAE group delays. Our results suggest that group delays calculated from the tip, the lower-frequency tail, or the above-BF region of ANF tuning curves do not match the CRF theory prediction. In obtaining the data to the test the CRF theory, we used two methods for obtaining ANF group delays at frequencies above BF: a previously published method and a simpler new method based on the same principle.
(cont.) Surprisingly, the two methods produced different results. Control measurements suggest that the previously published method does not do what it was expected to do.
by Holden Cheng.
S.M.

Nagelberg, Sara(Sara Nicole). "Dynamic and stimuli-responsive multi-phase emulsion droplets for optical components." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/127708.

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This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2020
Cataloged from student-submitted PDF of thesis.
Includes bibliographical references (pages 136-143).
Dynamic micro-optical components have revolutionized imaging, sensing, and display technologies. Multi-phase emulsions are micro-scale droplets formed from multiple immiscible material components suspended in a fluid medium. An interesting aspect of these droplets is that by tailoring the chemistry of the surrounding medium it is possible to control the droplet morphology or to render the droplets responsive to stimuli in the environment, including light, heat, specific molecules, or even bacteria. This thesis explores the optical characteristics of multi-phase droplets, including their refractive, emissive, and reflective properties. This work focuses predominantly on bi-phase droplets formed from two immiscible oils in water, which form double emulsions or Janus droplets. As tunable refractive components, these droplets form dynamic compound micro-lenses with adjustable focal length that is continuously variable from converging lenses to diverging lenses.
Macroscopically these refractive droplets can appear nearly transparent or strongly scattering, depending on their configurations. When a fluorescent dye is dispersed within the higher refractive index phase, a portion of the light emitted will undergo total internal reflection. This results in a strong morphology-dependent angular emission profile, which can be used in molecular sensing for chemicals or pathogens. In reflection, the droplets produce striking iridescent colors. This is due to the interference light being totally internally reflected at the internal interface along distinct optical paths, leading to color. These optical characteristics are analyzed both experimentally and theoretically. Finite Difference Time Domain simulations were used to model wave-optical effects and phenomena that could be treated using geometrical optics were calculated using a custom-built ray tracing algorithm.
Additionally, a theoretical model was developed to explain the iridescent colors, under a geometric approximation that takes into account interference effects. Experimentally the droplets were characterized using several different custom-built microscope setups. Beyond the optical characteristics, we used these setups to investigate the effects of thermal Marangoni flows within the droplets, which cause the droplets to re-orient towards a heat source. This work sets the foundation of understanding the refractive, reflective, and emissive properties of multi-phase droplets, which could form the basis of dynamically controllable or stimuli-responsive micro-scale optical components.
by Sara Nagelberg.
Ph. D.
Ph.D. Massachusetts Institute of Technology, Department of Mechanical Engineering

Snyder, Savannah R. "PROBING STRUCTURE-PROPERTY RELATIONSHIPS OF STIMULI-RESPONSIVE POLYMERS BY MULTI-DIMENSIONAL MASS SPECTROMETRY." University of Akron / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=akron1597353164970207.

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Zhu, Yanan. "Conception, synthèse et caractérisation d'un nouveau matériau multi-stimuli-responsive à base de spiropyranne." Mémoire, Université de Sherbrooke, 2016. http://hdl.handle.net/11143/8802.

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Ce mémoire de maîtrise porte sur la conception et la synthèse de monomères polymérisables en vue d’obtenir des macromolécules sensibles à plusieurs stimulations externes : 1) la lumière, 2) le pH (ou le CO[indice inférieur 2]) et 3) l’oxydo-réduction.

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Книги з теми "Multi-stimuli response":

Peng, Tao. Permeability of responsive polymer -- grafted porous membranes: Temperature, pH and multi-stimuli response. 2000.

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Serences, John T., and Sabine Kastner. A Multi-level Account of Selective Attention. Edited by Anna C. (Kia) Nobre and Sabine Kastner. Oxford University Press, 2014. http://dx.doi.org/10.1093/oxfordhb/9780199675111.013.022.

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To achieve behavioural goals, relevant sensory stimuli must be processed more quickly and reliably than irrelevant distracters. The ability to prioritize relevant over irrelevant stimuli is usually referred to as selective information processing, or selective attention. Over the last 50–60 years, there has been an ongoing debate about the point along the sensory–response processing stream at which selective attention operates: are relevant and irrelevant inputs segregated early in processing based on low-level featural differences, or does this segregation occur late in processing after the meaning of each stimulus has been computed? As with nearly all dichotomies in psychology, the emerging consensus is that neither extreme is correct. Instead, depending on task demands, the mechanisms of selective attention can flexibly operate on the quality of low-level sensory representations as well as on later stages of semantic analysis and decision-making.

Частини книг з теми "Multi-stimuli response":

Chu, Liang-Yin. "Dual-/Multi-Stimuli-Responsive Smart Membranes." In Advanced Topics in Science and Technology in China, 241–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-18114-6_11.

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Ge, Yan, Ping Lv, Christoph A. Schalley, and Zhenhui Qi. "Chapter 3. Multi-stimuli Responsive Materials." In Smart Materials Series, 47–95. 2nd ed. Cambridge: Royal Society of Chemistry, 2022. http://dx.doi.org/10.1039/9781839166136-00047.

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Poornima Vijayan, P., Jesiya Susan George, and R. V. Revathy. "Self-healing Epoxy Resin with Multi-Stimuli-Responsive Behavior." In Engineering Materials, 161–74. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-6038-3_6.

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Wiktorowicz, Szymon, Heikki Tenhu, and Vladimir Aseyev. "Multi-stimuli-responsive Polymers Based on Calix[4]arenes and Dibenzo-18-crown-6-ethers." In Temperature-Responsive Polymers, 145–74. Chichester, UK: John Wiley & Sons Ltd, 2018. http://dx.doi.org/10.1002/9781119157830.ch6.

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Nagelberg, Sara. "Introduction." In Dynamic and Stimuli-Responsive Multi-Phase Emulsion Droplets for Optical Components, 1–11. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53460-8_1.

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Nagelberg, Sara. "Multi-Phase Droplets as Dynamic Compound Micro-Lenses." In Dynamic and Stimuli-Responsive Multi-Phase Emulsion Droplets for Optical Components, 13–31. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53460-8_2.

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Nagelberg, Sara. "Emissive Bi-Phase Droplets as Pathogen Sensors." In Dynamic and Stimuli-Responsive Multi-Phase Emulsion Droplets for Optical Components, 33–43. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53460-8_3.

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Nagelberg, Sara. "Structural Color from Interference of Light Undergoing Total Internal Reflection at Concave Interfaces." In Dynamic and Stimuli-Responsive Multi-Phase Emulsion Droplets for Optical Components, 45–69. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53460-8_4.

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Nagelberg, Sara. "Thermal Actuation of Bi-Phase Droplets." In Dynamic and Stimuli-Responsive Multi-Phase Emulsion Droplets for Optical Components, 71–82. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53460-8_5.

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Nagelberg, Sara. "Summary and Outlook." In Dynamic and Stimuli-Responsive Multi-Phase Emulsion Droplets for Optical Components, 83–84. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53460-8_6.

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Тези доповідей конференцій з теми "Multi-stimuli response":

Olivari, Mario, Frank Nieuwenhuizen, Joost Venrooij, Heinrich Bülthoff, and Lorenzo Pollini. "Multi-loop Pilot Behavior Identification in Response to Simultaneous Visual and Haptic Stimuli." In AIAA Modeling and Simulation Technologies Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 2012. http://dx.doi.org/10.2514/6.2012-4795.

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Swathi, C. M., and K. H. Thippeswamy. "Prediction of Neural Response to Visual Stimuli of FMRI data Using Multi-Voxel Pattern Analysis." In Second International Conference on Signal Processing, Image Processing and VLSI. Singapore: Research Publishing Services, 2015. http://dx.doi.org/10.3850/978-981-09-6200-5_d-24.

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Kliger, Libi, and Galit Yovel. "Category-selectivity together with a Normalization Model Predicts the Response to Multi-category Stimuli along the Category-Selective Cortex." In 2019 Conference on Cognitive Computational Neuroscience. Brentwood, Tennessee, USA: Cognitive Computational Neuroscience, 2019. http://dx.doi.org/10.32470/ccn.2019.1196-0.

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Kim, Hyeonyu, Devin Neal, and H. Harry Asada. "Towards the Development of Optogenetically-Controlled Skeletal Muscle Actuators." In ASME 2013 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/dscc2013-4062.

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Engineered skeletal muscle tissue has the potential to be used as dual use actuator and stress-bearing material providing numerous degrees of freedom and with significant active stress generation. To exploit the potential features, however, technologies must be established to generate mature muscle strips that can be controlled with high fidelity. Here, we present a method for creating mature 3-D skeletal muscle tissues that contract in response to optical activation stimuli. The muscle strips are fascicle-like, consisting of several mm-long multi-nucleate muscle cells bundled together. We have found that applying a tension to the fascicle-like muscle tissue promotes maturation of the muscle. The fascicle-like muscle tissue is controlled with high spatiotemporal resolution based on optogenetic coding. The mouse myoblasts C2C12 were transfected with Channelrhodopsin-2 to enable light (∼470 nm) to control muscle contraction. The 3D muscle tissue not only twitches in response to an impulse light beam, but also exhibits a type of tetanus, a prolonged contraction of continuous stimuli, for the first time. In the following, the materials and culturing method used for 3D muscle generation is presented, followed by experimental results of muscle constructs and optogenetic control of the 3D muscle tissue.

Sarkar, Daipayan, Ankur Jain, and A. Haji-Sheikh. "Analytical Temperature Distribution in a Multi-Layer Tissue Structure in the Presence of a Tumor." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-63275.

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Analytical study of bioheat transfer is of significant importance for a number of biomedical applications including cryopreservation of tissue and thermal therapy for cancer. A sound fundamental understanding of thermal behavior of tissue in response to an externally applied stimulus helps design effective therapies and protocols. This paper derives an analytical solution in a multi-layer two-dimensional structure with arbitrary, space-dependent heat generation occurring in each layer. This geometry effectively models multiple layers of skin, with heat generation due to cancerous cells in the basal layer. The Pennes bioheat transfer equation is solved for the multi-layer analytically, wherein the temperature in each layer is explicitly a function of space and the thermo-physical properties of the layer. The resulting analytical temperature profile agrees well with finite-element simulations and is also in good agreement with a previously published experimental study. Results derived in this work illustrate the effect of the presence of cancerous cells on the thermal profile of the skin. Further, the model helps to understand the effect of external cooling and heating stimuli.

Phamduy, Paul, Miguel Vazquez, Alessandro Rizzo, and Maurizio Porfiri. "Miniature Underwater Robotic Fish for Animal-Robot Interactions." In ASME 2016 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/dscc2016-9857.

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Research in animal behavior has benefited from the availability of robots able to elicit controllable, customizable, and versatile stimuli in behavioral studies. For example, biologically-inspired robotic fish can be designed to mimic the morphophysiology of predators and conspecifics to study fear response and sociality. However, size is a critical limitation of the existing arrays of robotic fish. Here, we present the design of a miniature robotic fish for future animal-robot interaction studies featuring a novel application of multi-material three-dimensional (3D) printing and utilizing a solenoid for actuation. The use of multi-material printing enables a skeletal design of only two parts, while retaining the complete functionality of larger prototypes enclosing requisite electronics and incorporating an active joint for propulsion. Parametric tests are conducted to test the swimming speed of the robotic fish and a compact dynamic model with two degrees of freedom to elucidate swimming of the robotic fish is presented.

Lin Li, J. S. Choi, J. T. Francis, J. C. Sanchez, and J. C. Principe. "Decoding stimuli from multi-source neural responses." In 2012 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2012. http://dx.doi.org/10.1109/embc.2012.6346183.

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Kaneko, Tatsuo, Takashi Miyazaki, Kanji Yamaoka, Yuichi Katayama, Atsushi Matsuda, Jianping Gong, and Yoshihito Osada. "Shape memory gels with multi-stimuli-responses." In 1999 Symposium on Smart Structures and Materials, edited by Yoseph Bar-Cohen. SPIE, 1999. http://dx.doi.org/10.1117/12.349678.

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Orosz, Ga´bor, Jeff Moehlis, and Francesco Bullo. "Delayed Car-Following Dynamics for Human and Robotic Drivers." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-48829.

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A general class of car-following models is analyzed where the longitudinal acceleration of a vehicle is determined by a nonlinear function of the distance to the vehicle in front, their velocity difference, and the vehicle’s own velocity. The driver’s response to these stimuli includes the driver reaction time that appears as a time delay in governing differential equations. The linear stability of the uniform flow is analyzed for human-driven and computer-controlled (robotic) vehicles. It is shown that the stability conditions are equivalent when considering ring-road and platoon configurations. It is proven that time delays result in novel high-frequency oscillations that manifest themselves as short-wavelength traveling waves. The theoretical results are illustrated using an optimal velocity model where the nonlinear behavior is also revealed by numerical simulations. The results may lead to better understanding of multi-vehicle dynamics and allow one to design cooperative autonomous cruise control algorithms.

Zhang, Wei, Anil Erol, Saad Ahmed, Sarah Masters, Paris von Lockette, Zoubeida Ounaies, and Mary Frecker. "Finite Element Analysis of Electroactive and Magnetoactive Coupled Behaviors in Multi-Field Origami Structures." In ASME 2017 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/smasis2017-3850.

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Active origami designs, which incorporate smart materials such as electroactive polymers (EAPs) and magnetoactive elastomers (MAEs) into mechanical structures, have shown good promise in engineering applications. In this study, finite element analysis (FEA) models are developed using COMSOL Multiphysics software for two configurations that incorporate a combination of active and passive material layers, namely: 1) a single-notch unimorph folding configuration actuated using only external electric field and 2) a bimorph configuration which is actuated using both electric and magnetic (i.e. multifield) stimuli. Constitutive relations are developed for both electrostrictive and magnetoactive materials to model the coupled behaviors directly. Shell elements are adopted for their capacity of modeling thin films, reduction of computational cost and ability to model the intrinsic coupled behaviors in the active materials under consideration. A microstructure-based constitutive model for electromechanical coupling is introduced to capture the nonlinearity of the EAP’s relaxor ferroelectric response; the electrostrictive coefficients are then used as input in the constitutive modeling of the coupled behavior. The magnetization of the MAE is measured by experiment and then used to calculate magnetic torque under specified external magnetic field. The objective of the study is to verify the effectiveness of the constitutive models to simulate multi-field coupled behaviors of the active origami configurations. Through quantitative comparisons, simulation results show good agreement with experimental data, which is a good validation of the shell models. By investigating the impact of material selection, location, and geometric parameters, FEA can be used in design, reducing trial-and-error iterations in experiments.